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Conserved domains on  [gi|1634511812|ref|WP_137087804|]
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MULTISPECIES: carbohydrate ABC transporter permease [Rhizobium/Agrobacterium group]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 9-349 6.32e-98

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 291.23  E-value: 6.32e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812   9 TRTRRPGRIGLTDILSWVWLIGGTLAVLIPVVWAAMSSLKPEAEITRFPPSLLPRaavqvevqgydkplslwkapidgme 88
Cdd:COG0395     2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPS------------------------- 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812  89 remamvrriglkaqmvdpanpgppvsvdtreispvqklTIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAA 168
Cdd:COG0395    57 --------------------------------------EFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAA 98

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 169 FALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTVA--TPTGVFLLRQYMLTIPDELIEAA 246
Cdd:COG0395    99 YALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEAA 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 247 RVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLQVGLNAFQGEFSVQWHYILAMTFLSLA 326
Cdd:COG0395   179 RIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATL 258

                         330       340
                  ....*....|....*....|...
gi 1634511812 327 PVTVVFLFLQRYITTGIAGTGMK 349
Cdd:COG0395   259 PVLILFLFLQRYFVRGLTAGAVK 281
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 9-349 6.32e-98

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 291.23  E-value: 6.32e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812   9 TRTRRPGRIGLTDILSWVWLIGGTLAVLIPVVWAAMSSLKPEAEITRFPPSLLPRaavqvevqgydkplslwkapidgme 88
Cdd:COG0395     2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPS------------------------- 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812  89 remamvrriglkaqmvdpanpgppvsvdtreispvqklTIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAA 168
Cdd:COG0395    57 --------------------------------------EFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAA 98

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 169 FALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTVA--TPTGVFLLRQYMLTIPDELIEAA 246
Cdd:COG0395    99 YALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEAA 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 247 RVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLQVGLNAFQGEFSVQWHYILAMTFLSLA 326
Cdd:COG0395   179 RIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATL 258

                         330       340
                  ....*....|....*....|...
gi 1634511812 327 PVTVVFLFLQRYITTGIAGTGMK 349
Cdd:COG0395   259 PVLILFLFLQRYFVRGLTAGAVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
142-343 1.65e-37

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 135.63  E-value: 1.65e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 142 FLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPT 221
Cdd:PRK10973   73 FGRMLLNSFVMAFSITVGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPL 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 222 VATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLQV 301
Cdd:PRK10973  153 MASATATFLFRQFFMTLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVA 232

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1634511812 302 GLNAF--QGEFSVQWHYILAMTFLSLAPVTVVFLFLQRYITTGI 343
Cdd:PRK10973  233 GIKGMiaTGEGTTEWNQVMAAMLLTLIPPVVIVLAMQRAFVRGL 276
ABC_arch_GlcU NF040932
glucose ABC transporter permease GlcU;
140-349 8.63e-31

glucose ABC transporter permease GlcU;


Pssm-ID: 468865  Cd Length: 272  Bit Score: 117.80  E-value: 8.63e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 140 FSFLTFLKNSVFVTFVATVLTLIVNAMAAFA---LSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWG 216
Cdd:NF040932   56 SGLAPPLINSLIVVIPVALISTFLGAMGAYFfyrLSERHSILSDFLFSLIALATFIPYQATLVPLTRLEVSLGLFNTYWG 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 217 VIIPTVA--TPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSR 294
Cdd:NF040932  136 LIFALLIfyIPTAALLMSIFIPVLPKYLIEAARIDGASDWTIFWKVVLPLTVPGFISTLIFIFIESWNNFFIPLVLTTTP 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1634511812 295 ENFTLQVGLNAFQGEFSVQWHYILAMTFLSLAPVTVVFLFLQRYITTGIA--GTGMK 349
Cdd:NF040932  216 SMRLIPVAVRSYTGGYGTLYNESFAAAVIASIVPLLIFIFLGRYFIRGLAalGGGGK 272
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 146-328 1.41e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 82.33  E-value: 1.41e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 146 LKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTVA-- 223
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALIla 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 224 ----TPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTL 299
Cdd:cd06261    81 llliAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180
                  ....*....|....*....|....*....
gi 1634511812 300 QVGLNAFQGEFSVQWHYILAMTFLSLAPV 328
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 164-339 6.14e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.47  E-value: 6.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 164 NAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTV--ATPTGVFLLRQYMLTIPDE 241
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALlgWAGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 242 LIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLqvGLNAFQGEFSVQWHYILAMT 321
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLL--LIEAILGYDYPEIQGPVLAA 159

                         170
                  ....*....|....*...
gi 1634511812 322 FLSLAPVTVVFLFLQRYI 339
Cdd:pfam00528 160 ALILLLLNLLVDILQRLL 177
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 9-349 6.32e-98

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 291.23  E-value: 6.32e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812   9 TRTRRPGRIGLTDILSWVWLIGGTLAVLIPVVWAAMSSLKPEAEITRFPPSLLPRaavqvevqgydkplslwkapidgme 88
Cdd:COG0395     2 SATARRRRRRLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPS------------------------- 56

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812  89 remamvrriglkaqmvdpanpgppvsvdtreispvqklTIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAA 168
Cdd:COG0395    57 --------------------------------------EFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAA 98

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 169 FALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTVA--TPTGVFLLRQYMLTIPDELIEAA 246
Cdd:COG0395    99 YALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRELEEAA 178

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 247 RVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLQVGLNAFQGEFSVQWHYILAMTFLSLA 326
Cdd:COG0395   179 RIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATL 258

                         330       340
                  ....*....|....*....|...
gi 1634511812 327 PVTVVFLFLQRYITTGIAGTGMK 349
Cdd:COG0395   259 PVLILFLFLQRYFVRGLTAGAVK 281
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 127-349 1.11e-58

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 190.75  E-value: 1.11e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 127 TIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIV 206
Cdd:COG3833    56 NFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLS 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 207 GVGLVDNLWGVIIPTVAT--PTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDF 284
Cdd:COG3833   136 ALGLLNTLLGLILVYLGGaiPFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDF 215

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1634511812 285 LWPLIVLSSRENFTLQVGLNAF-QGEFSVQWHYILAMTFLSLAPVTVVFLFLQRYITTGIAGTGMK 349
Cdd:COG3833   216 ILASVLLRSPENYTLAVGLYSFvSDQRNTNWGVFAAGAVLVAIPIVILFLFLQRYLVSGLTAGGVK 281
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
142-343 1.65e-37

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 135.63  E-value: 1.65e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 142 FLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPT 221
Cdd:PRK10973   73 FGRMLLNSFVMAFSITVGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPL 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 222 VATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLQV 301
Cdd:PRK10973  153 MASATATFLFRQFFMTLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVA 232

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1634511812 302 GLNAF--QGEFSVQWHYILAMTFLSLAPVTVVFLFLQRYITTGI 343
Cdd:PRK10973  233 GIKGMiaTGEGTTEWNQVMAAMLLTLIPPVVIVLAMQRAFVRGL 276
ABC_arch_GlcU NF040932
glucose ABC transporter permease GlcU;
140-349 8.63e-31

glucose ABC transporter permease GlcU;


Pssm-ID: 468865  Cd Length: 272  Bit Score: 117.80  E-value: 8.63e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 140 FSFLTFLKNSVFVTFVATVLTLIVNAMAAFA---LSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWG 216
Cdd:NF040932   56 SGLAPPLINSLIVVIPVALISTFLGAMGAYFfyrLSERHSILSDFLFSLIALATFIPYQATLVPLTRLEVSLGLFNTYWG 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 217 VIIPTVA--TPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSR 294
Cdd:NF040932  136 LIFALLIfyIPTAALLMSIFIPVLPKYLIEAARIDGASDWTIFWKVVLPLTVPGFISTLIFIFIESWNNFFIPLVLTTTP 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1634511812 295 ENFTLQVGLNAFQGEFSVQWHYILAMTFLSLAPVTVVFLFLQRYITTGIA--GTGMK 349
Cdd:NF040932  216 SMRLIPVAVRSYTGGYGTLYNESFAAAVIASIVPLLIFIFLGRYFIRGLAalGGGGK 272
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 130-339 4.20e-23

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 96.72  E-value: 4.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 130 TENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVG 209
Cdd:COG1177    47 LRWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALG 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 210 LVDNLWGVIIP--TVATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWP 287
Cdd:COG1177   127 LSGGLWGLILAhvVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVIT 206

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1634511812 288 LIVLSSRENfTLQVGL-NAFQGEFSvqwHYILAMTFLSLAPVTVVFLFLQRYI 339
Cdd:COG1177   207 LFLAGPGVT-TLPVYIySMIRRGIS---PEINALSTLLILLSLLLLLLAERLR 255
malG PRK10998
maltose ABC transporter permease MalG;
140-349 2.87e-20

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 89.38  E-value: 2.87e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 140 FSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGL------VDN 213
Cdd:PRK10998   79 FPVLLWLWNSVKVAGITAIGIVALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQyipfigLNT 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 214 LWGVIIPTVA-TPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLS 292
Cdd:PRK10998  159 HGGVIFAYLGgIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLR 238

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1634511812 293 SRENFTLQVGLNAFQGEFSVQWHYILAMTFLSLAPVTVVFLFLQRYITTGIAGTGMK 349
Cdd:PRK10998  239 DVNSYTLAVGMQQYLNPQNYLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 146-328 1.41e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 82.33  E-value: 1.41e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 146 LKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTVA-- 223
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALIla 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 224 ----TPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTL 299
Cdd:cd06261    81 llliAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170       180
                  ....*....|....*....|....*....
gi 1634511812 300 QVGLNAFQGEFSVQWHYILAMTFLSLAPV 328
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
131-284 5.22e-15

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 74.40  E-value: 5.22e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 131 ENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKyRFRGEKAIFVLIISTLMIPLTVV------------- 197
Cdd:COG1175    63 DNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVValiwkwlfnpdyg 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 198 MVPAYLVIVGVGLVD-------NLWGVIIPTV--ATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPA 268
Cdd:COG1175   142 LLNALLGALGLEPINwlgdpslALPAVIIVTVwkGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPT 221

                         170
                  ....*....|....*.
gi 1634511812 269 LAVLAIFSVLWRWNDF 284
Cdd:COG1175   222 ILFVLVLSTIGALQVF 237
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
126-274 1.32e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 74.43  E-value: 1.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 126 LTIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPlTVVMVPAYLVI 205
Cdd:COG1178    36 FTDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALP-PYVVALAWIAL 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 206 VG-VGLVDNLW----GVIIPTVATPTGV-------------FLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAP 267
Cdd:COG1178   115 FGpNGLLNTLLralfGLEPPDIYGLGGIilvlvlfnypyvyLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRP 194


                  ....*..
gi 1634511812 268 ALAVLAI 274
Cdd:COG1178   195 AIAAGAL 201
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 164-339 6.14e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 63.47  E-value: 6.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 164 NAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIPTV--ATPTGVFLLRQYMLTIPDE 241
Cdd:pfam00528   2 IPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALlgWAGYARLIRRAALRSLPSD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 242 LIEAARVDAASEFRIFWRIILPLTAPALAVLAIFSVLWRWNDFLWPLIVLSSRENFTLqvGLNAFQGEFSVQWHYILAMT 321
Cdd:pfam00528  82 LVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLL--LIEAILGYDYPEIQGPVLAA 159

                         170
                  ....*....|....*...
gi 1634511812 322 FLSLAPVTVVFLFLQRYI 339
Cdd:pfam00528 160 ALILLLLNLLVDILQRLL 177
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
120-276 1.53e-11

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.18  E-value: 1.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 120 ISPVQKLTIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVV-- 197
Cdd:COG1178   314 LTKALDDNLTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLgl 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 198 -MVPAYLVIVGVGLVDNLWGVIIPTV--ATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALAVLAI 274
Cdd:COG1178   394 gLLLLFNRPLPLLLYGTLAILVLAYVvrFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAAL 473


                  ..
gi 1634511812 275 FS 276
Cdd:COG1178   474 LV 475
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 131-270 2.14e-11

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 63.62  E-value: 2.14e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 131 ENFTDPLTRFSfltfLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLI-----ISTLMIPLTVVM------- 198
Cdd:COG0555    45 AVLTSPRVLAA----LKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVdlpfaLPTAVAGIALLLlfgpngw 120

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1634511812 199 VPAYLVIVGVGLVDNLWGVIIP--TVATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALA 270
Cdd:COG0555   121 LGQLLAPLGIKVAFTPLGIVLAqtFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALL 194
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 113-275 2.48e-11

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 63.63  E-value: 2.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 113 VSVDTREISPVQKLTIATENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMI 192
Cdd:COG1176    36 YSFTTRDPYGGVVPGFTLENYARLFTDPLYLKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWT 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 193 PLtVVMVPAYLVI-----------VGVGLVD-------NLWGVIIPTVAT--PTGVFLLRQYMLTIPDELIEAARVDAAS 252
Cdd:COG1176   116 SF-LVRTYAWIVLlgrngllnsllLALGLIDeplrllyTEFAVVIGLVYVylPFMVLPLYAALEKIDPSLLEAARDLGAS 194

                         170       180
                  ....*....|....*....|...
gi 1634511812 253 EFRIFWRIILPLTAPALAVLAIF 275
Cdd:COG1176   195 PWQTFRRVILPLSLPGIIAGSLL 217
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 141-273 2.67e-11

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 62.37  E-value: 2.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 141 SFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVpaYLVIV-------------- 206
Cdd:COG4149     4 EDWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGF--YLLLLfgrngplgqlleel 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1634511812 207 -GVGLVDNLWGVIIPT--VATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPAL---AVLA 273
Cdd:COG4149    82 fGISLVFTWTGAVLASvvVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGIlagAVLA 154
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 148-270 1.28e-10

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 61.15  E-value: 1.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 148 NSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLIISTLMIPLTVVMVPAYLVIVGVGLVDNLWGVIIP--TVATP 225
Cdd:PRK09500   61 HSLTMAVFSATFATLIGSLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFAhiTFCLP 140

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1634511812 226 TGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPALA 270
Cdd:PRK09500  141 FVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVA 185
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 130-284 8.43e-04

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 40.76  E-value: 8.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 130 TENFTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAI-----FVLIISTLMIPLTVVMV----- 199
Cdd:PRK15050   59 LATYRAVLGSPDFRGALLTTLQIAFASTAGCLVLGVLLALVLAFVPFPGASLVgrfidTFVAFPSFLITLAFTFLygsag 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 200 -----PAYLVIVGVGLVDNL---WGVIIP--TVATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPAL 269
Cdd:PRK15050  139 svniaLQRLFGLEAPPLDFLyspGGVILAeiTFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPAL 218

                         170
                  ....*....|....*
gi 1634511812 270 AVLAIFSVLWRWNDF 284
Cdd:PRK15050  219 AAGGSLCLLLTLNEF 233
cysT CHL00187
sulfate transport protein; Provisional
 149-269 9.82e-04

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 40.00  E-value: 9.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 149 SVFVTFVATVLTLIVNAMAAFALSKYRFRGEKAIFVLI-----ISTLMIPLTVVMVPA-------YLVIVGVGLVDNLWG 216
Cdd:CHL00187   60 TLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVdlpfaLPTSVAGLTLATVYGdngwighLLSHLGIQIVFTKLG 139

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1634511812 217 VIIP--TVATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPAL 269
Cdd:CHL00187  140 VLLAmiFVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPAL 194
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 133-269 4.18e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.21  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 133 FTDPLTRFSFLTFLKNSVFVTFVATVLTLIVNAMAAFALSKYRFrGEKAIFVLIISTLMIPLtVVMVPAYLVIVGVGLVD 212
Cdd:COG0600    50 LVELLASGELWEHLLASLLRVLLGFALAALLGVPLGLLLGLSRL-LRRLLDPLLVFLRPIPP-LALAPLLILWFGIGEAS 127

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1634511812 213 NLWGVIIptVATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPAL 269
Cdd:COG0600   128 KIFVIFL--GAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYI 182
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
192-269 6.83e-03

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 37.41  E-value: 6.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634511812 192 IPLTVVMVPAYLVIVGVGLvdNLWGVIIP-TV-ATPTGVFLLRQYMLTIPDELIEAARVDAASEFRIFWRIILPLTAPAL 269
Cdd:PRK10782   69 IILLVWMIPFTRVIVGTSI--GLQAAIVPlTVgAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGL 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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