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Conserved domains on  [gi|1655481556|ref|WP_137773380|]
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cell division protein SepF [Citricoccus sp. SGAir0253]

Protein Classification

cell division protein SepF( domain architecture ID 10004532)

cell division protein SepF assembles into large protein rings which bundle FtsZ protofilaments that assemble into a Z ring, which acts as a scaffold for cell division proteins; SepF also anchors the Z ring to the cell membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SepF COG1799
Cell division protein SepF/YlmF, interacts with FtsZ [Cell cycle control, cell division, ...
 2-192 7.19e-54

Cell division protein SepF/YlmF, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 441404 [Multi-domain]  Cd Length: 142  Bit Score: 168.10  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556   2 AGALKKTMIYLGLADgDEHYEEdqraveprrhdrpeqdepagahdrgeredraeawEDEAREERPQPSRvapavpaEREY 81
Cdd:COG1799     1 MGLFDKLKNFFGLED-EEEYEE----------------------------------YEEPEEEEPAPAK-------PAKK 38

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556  82 RAPVTPIKRAAQSreeasaVRQITTVHPRSYNDAKVIGESFRSGIPVIMNVTDMSESDAKRLVDFSAGLVFGLHGSIERV 161
Cdd:COG1799    39 KANVVPLHSATSS------QSKIVVVEPRSYEDAQEIADHLRNGKPVIVNLERMDDDQAKRIVDFLSGLVYALDGSIQKV 112

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1655481556 162 TNKVFLLTPSNVQVLGEDTSGAEDQShFFNQ 192
Cdd:COG1799   113 GNKIFLLTPSNVEVSGEIKEELAEKG-FFNW 142
 
Name Accession Description Interval E-value
SepF COG1799
Cell division protein SepF/YlmF, interacts with FtsZ [Cell cycle control, cell division, ...
 2-192 7.19e-54

Cell division protein SepF/YlmF, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441404 [Multi-domain]  Cd Length: 142  Bit Score: 168.10  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556   2 AGALKKTMIYLGLADgDEHYEEdqraveprrhdrpeqdepagahdrgeredraeawEDEAREERPQPSRvapavpaEREY 81
Cdd:COG1799     1 MGLFDKLKNFFGLED-EEEYEE----------------------------------YEEPEEEEPAPAK-------PAKK 38

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556  82 RAPVTPIKRAAQSreeasaVRQITTVHPRSYNDAKVIGESFRSGIPVIMNVTDMSESDAKRLVDFSAGLVFGLHGSIERV 161
Cdd:COG1799    39 KANVVPLHSATSS------QSKIVVVEPRSYEDAQEIADHLRNGKPVIVNLERMDDDQAKRIVDFLSGLVYALDGSIQKV 112

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1655481556 162 TNKVFLLTPSNVQVLGEDTSGAEDQShFFNQ 192
Cdd:COG1799   113 GNKIFLLTPSNVEVSGEIKEELAEKG-FFNW 142
SepF pfam04472
Cell division protein SepF; SepF accumulates at the cell division site in an FtsZ-dependent ...
 104-175 5.63e-30

Cell division protein SepF; SepF accumulates at the cell division site in an FtsZ-dependent manner and is required for proper septum formation. Mutants are viable but the formation of the septum is much slower and occurs with a very abnormal morphology. This family also includes archaeal related proteins of unknown function.


Pssm-ID: 461323  Cd Length: 72  Bit Score: 105.19  E-value: 5.63e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1655481556 104 ITTVHPRSYNDAKVIGESFRSGIPVIMNVTDMSESDAKRLVDFSAGLVFGLHGSIERVTNKVFLLTPSNVQV 175
Cdd:pfam04472   1 VVVVEPRSFEDAQEIADALKNGKIVILNLEGLDKEDAQRIVDFLSGAVYALDGDIQRVGNKIFLLTPSNVDI 72
ALDH_PhdK-like cd07107
Nocardioides 2-carboxybenzaldehyde dehydrogenase, PhdK-like; Nocardioides sp. strain ...
 71-157 1.29e-03

Nocardioides 2-carboxybenzaldehyde dehydrogenase, PhdK-like; Nocardioides sp. strain KP72-carboxybenzaldehyde dehydrogenase (PhdK), an enzyme involved in phenanthrene degradation, and other similar sequences, are present in this CD.


Pssm-ID: 143425 [Multi-domain]  Cd Length: 456  Bit Score: 38.90  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556  71 VAPAVPAEREYRApVTPIKRAAQSREEASAVRQittvHPRSYndakVIGESFRSGIPVIMNVTDMSEsdAKRLVDFSAGL 150
Cdd:cd07107    25 VAAARAAFPEWRA-TTPLERARMLRELATRLRE----HAEEL----ALIDALDCGNPVSAMLGDVMV--AAALLDYFAGL 93


                  ....*..
gi 1655481556 151 VFGLHGS 157
Cdd:cd07107    94 VTELKGE 100
 
Name Accession Description Interval E-value
SepF COG1799
Cell division protein SepF/YlmF, interacts with FtsZ [Cell cycle control, cell division, ...
 2-192 7.19e-54

Cell division protein SepF/YlmF, interacts with FtsZ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441404 [Multi-domain]  Cd Length: 142  Bit Score: 168.10  E-value: 7.19e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556   2 AGALKKTMIYLGLADgDEHYEEdqraveprrhdrpeqdepagahdrgeredraeawEDEAREERPQPSRvapavpaEREY 81
Cdd:COG1799     1 MGLFDKLKNFFGLED-EEEYEE----------------------------------YEEPEEEEPAPAK-------PAKK 38

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556  82 RAPVTPIKRAAQSreeasaVRQITTVHPRSYNDAKVIGESFRSGIPVIMNVTDMSESDAKRLVDFSAGLVFGLHGSIERV 161
Cdd:COG1799    39 KANVVPLHSATSS------QSKIVVVEPRSYEDAQEIADHLRNGKPVIVNLERMDDDQAKRIVDFLSGLVYALDGSIQKV 112

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1655481556 162 TNKVFLLTPSNVQVLGEDTSGAEDQShFFNQ 192
Cdd:COG1799   113 GNKIFLLTPSNVEVSGEIKEELAEKG-FFNW 142
SepF pfam04472
Cell division protein SepF; SepF accumulates at the cell division site in an FtsZ-dependent ...
 104-175 5.63e-30

Cell division protein SepF; SepF accumulates at the cell division site in an FtsZ-dependent manner and is required for proper septum formation. Mutants are viable but the formation of the septum is much slower and occurs with a very abnormal morphology. This family also includes archaeal related proteins of unknown function.


Pssm-ID: 461323  Cd Length: 72  Bit Score: 105.19  E-value: 5.63e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1655481556 104 ITTVHPRSYNDAKVIGESFRSGIPVIMNVTDMSESDAKRLVDFSAGLVFGLHGSIERVTNKVFLLTPSNVQV 175
Cdd:pfam04472   1 VVVVEPRSFEDAQEIADALKNGKIVILNLEGLDKEDAQRIVDFLSGAVYALDGDIQRVGNKIFLLTPSNVDI 72
ALDH_PhdK-like cd07107
Nocardioides 2-carboxybenzaldehyde dehydrogenase, PhdK-like; Nocardioides sp. strain ...
 71-157 1.29e-03

Nocardioides 2-carboxybenzaldehyde dehydrogenase, PhdK-like; Nocardioides sp. strain KP72-carboxybenzaldehyde dehydrogenase (PhdK), an enzyme involved in phenanthrene degradation, and other similar sequences, are present in this CD.


Pssm-ID: 143425 [Multi-domain]  Cd Length: 456  Bit Score: 38.90  E-value: 1.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1655481556  71 VAPAVPAEREYRApVTPIKRAAQSREEASAVRQittvHPRSYndakVIGESFRSGIPVIMNVTDMSEsdAKRLVDFSAGL 150
Cdd:cd07107    25 VAAARAAFPEWRA-TTPLERARMLRELATRLRE----HAEEL----ALIDALDCGNPVSAMLGDVMV--AAALLDYFAGL 93


                  ....*..
gi 1655481556 151 VFGLHGS 157
Cdd:cd07107    94 VTELKGE 100
RMI1_N pfam08585
RecQ mediated genome instability protein; RMI1_N is an N-terminal family of eukaryotic ...
 141-177 2.84e-03

RecQ mediated genome instability protein; RMI1_N is an N-terminal family of eukaryotic proteins. The domain probably carries an oligo-nucleotide-binding domain or OB-fold, and forms a stable complex with Bloom syndrome protein BLM and DNA topoisomerase 3-alpha.


Pssm-ID: 462527  Cd Length: 194  Bit Score: 37.25  E-value: 2.84e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1655481556 141 KRLVDFSAGLVFG----LHGSIeRVTNKVFLLTPSNVQVLG 177
Cdd:pfam08585 141 KPIPGLSLKLPPGtkllLKGNV-VVRRGVLLLTPENVKVLG 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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