|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
1-444 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 867.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 1 MEMPLRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEE 80
Cdd:PRK05595 1 MDAPIRSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 81 CGGISYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSDFEPM 160
Cdd:PRK05595 81 AGGVTYITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDVEKVIDSAEKKIFDISEKRTTSDFEPL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 161 NTVLERGFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEM 240
Cdd:PRK05595 161 SNVLERGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 241 SKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYL 320
Cdd:PRK05595 241 SKEQLAYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHGIDMILIDYL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 321 QLMSGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYN 400
Cdd:PRK05595 321 QLMSGGKGSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYN 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1668483510 401 KETEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKFARLDIIHQE 444
Cdd:PRK05595 401 KETEDKNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNLDVIHQE 444
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
8-439 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 740.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 8 LPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGISYI 87
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 88 SEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSDFEPMNTVLERG 167
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 168 FLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAY 247
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQLVM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 248 KLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLQLMSGSS 327
Cdd:TIGR00665 241 RMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSGSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 328 GSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETEDKN 407
Cdd:TIGR00665 321 RSENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPDSEDKG 400
|
410 420 430
....*....|....*....|....*....|..
gi 1668483510 408 VAECIIAKQRNGPTGTVKLGWLGQYSKFARLD 439
Cdd:TIGR00665 401 IAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
11-439 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 730.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 11 NIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGISYISEI 90
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 91 SNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSDFEPMNTVLERGFLE 170
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 171 IERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAYKLL 250
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMRLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 251 CAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLQLMSGSSGSE 330
Cdd:COG0305 241 SSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGRSE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 331 SRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETEDKNVAE 410
Cdd:COG0305 321 NRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSEDKGIAE 400
|
410 420
....*....|....*....|....*....
gi 1668483510 411 CIIAKQRNGPTGTVKLGWLGQYSKFARLD 439
Cdd:COG0305 401 IIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
3-444 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 647.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 3 MPLRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECG 82
Cdd:PRK05748 5 AALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDLEEVG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 83 GISYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSDFEPMNT 162
Cdd:PRK05748 85 GLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFKNIKD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 163 VLERGFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSK 242
Cdd:PRK05748 165 VLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSLEMGA 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 243 EQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEH-GIDLIVIDYLQ 321
Cdd:PRK05748 245 ESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLILIDYLQ 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 322 LMSGS-SGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYN 400
Cdd:PRK05748 325 LIQGSgRSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRDDYYD 404
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1668483510 401 KETEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKFARLDIIHQE 444
Cdd:PRK05748 405 EETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
183-436 |
0e+00 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 505.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 183 GVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAYKLLCAEANVDMLKLR 262
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 263 TGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLQLMSGSSGSESRQQEVSEISRS 342
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSGGSRGENRQQEISEISRS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 343 IKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKEtEDKNVAECIIAKQRNGPTG 422
Cdd:pfam03796 161 LKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK-EPEGKAEIIIAKQRNGPTG 239
|
250
....*....|....
gi 1668483510 423 TVKLGWLGQYSKFA 436
Cdd:pfam03796 240 TVKLAFLGEYTRFE 253
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
6-391 |
9.03e-165 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 486.56 E-value: 9.03e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 6 RSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGIS 85
Cdd:PRK07773 22 RQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIGGAP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 86 YISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSDFEPMNTVLE 165
Cdd:PRK07773 102 YLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYAEGADVAEVVDRAQAEIYDVTDRRLSEDFVALEDLLQ 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 166 RGFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQL 245
Cdd:PRK07773 182 PTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRLAVAIFSLEMSKEQL 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 246 AYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLQLMSG 325
Cdd:PRK07773 262 VMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRLRQEANLGLIVVDYLQLMTS 341
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1668483510 326 SSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVM 391
Cdd:PRK07773 342 GKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGDTLILR 407
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
4-438 |
1.78e-163 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 469.40 E-value: 1.78e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 4 PLRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGG 83
Cdd:PRK08760 29 QLRVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPFDAVTLGEWFESQGKLEQVGD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 84 ISYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSG-AVENVIDLAERRIFNIAEN--RTTSDFEPM 160
Cdd:PRK08760 109 GAYLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQPEGrESIELLASAEKAVFKIAEAgaRGRTDFVAM 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 161 NTVLERGFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEM 240
Cdd:PRK08760 189 PGALKDAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFALNIAEYAAIKSKKGVAVFSMEM 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 241 SKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYL 320
Cdd:PRK08760 269 SASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVLRSKCRRLKREHDLGLIVIDYL 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 321 QLMSGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYN 400
Cdd:PRK08760 349 QLMSVPGNSENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRESGAIEQDADMIVFIYRDDYYN 428
|
410 420 430
....*....|....*....|....*....|....*....
gi 1668483510 401 KE-TEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKFARL 438
Cdd:PRK08760 429 KEnSPDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNL 467
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
9-438 |
1.65e-160 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 461.39 E-value: 1.65e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 9 PHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGISYIS 88
Cdd:PRK06904 24 PHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGGFAYLA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 89 EISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSG-AVENVIDLAERRIFNIAENRTTSDFEPMNTV--LE 165
Cdd:PRK06904 104 ELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYSPKGqDIKDILDEAERDVFSIAEKRTTANEGPQNVInlLE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 166 RGFLEIERLF---NNKGeITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSK 242
Cdd:PRK06904 184 NTIDKIENLAatpTNNG-VTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLEMPA 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 243 EQLAYKLLCAEANVDMLKLRTG-DLEDKDWENIAKASGPLA-AANIYIDDTAGVSVMEMRSKCRRLKLEHG-IDLIVIDY 319
Cdd:PRK06904 263 EQIMMRMLASLSRVDQTKIRTGqNLDQQDWAKISSTVGMFKqKPNLYIDDSSGLTPTELRSRARRVYRENGgLSLIMVDY 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 320 LQLMSGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYY 399
Cdd:PRK06904 343 LQLMRAPGFEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQDADLIMFIYRDEVY 422
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1668483510 400 NKETED-KNVAECIIAKQRNGPTGTVKLGWLGQYSKFARL 438
Cdd:PRK06904 423 NETTEDnKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNL 462
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
5-435 |
7.55e-159 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 456.68 E-value: 7.55e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 5 LRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGI 84
Cdd:PRK07004 12 LKVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 85 SYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGA-VENVIDLAERRIFNIAEN--RTTSDFEPMN 161
Cdd:PRK07004 92 AYLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFNPQGKeVRQLLDEAESKVFSIAEEgaRGTQGFLEIG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 162 TVLERGFLEIERLFN--NKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLE 239
Cdd:PRK07004 172 PLLTQVVERIDTLYHtaNPSDVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGLPVAVFSME 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 240 MSKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHG-IDLIVID 318
Cdd:PRK07004 252 MPGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLARQCGkLGLIIID 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 319 YLQLMSGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEY 398
Cdd:PRK07004 332 YLQLMSGSSQGENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEV 411
|
410 420 430
....*....|....*....|....*....|....*..
gi 1668483510 399 YNKETEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKF 435
Cdd:PRK07004 412 YNPDSPDKGTAEIIIGKQRNGPIGPVRLTFLGQYTKF 448
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
183-435 |
1.94e-158 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 447.73 E-value: 1.94e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 183 GVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAYKLLCAEANVDMLKLR 262
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 263 TGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHG-IDLIVIDYLQLMSGSSGSESRQQEVSEISR 341
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGgLGLIVIDYLQLIRGSKRAENRQQEVAEISR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 342 SIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETEDKNVAECIIAKQRNGPT 421
Cdd:cd00984 161 SLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGPT 240
|
250
....*....|....
gi 1668483510 422 GTVKLGWLGQYSKF 435
Cdd:cd00984 241 GTVYLAFNPEYTRF 254
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
2-445 |
2.27e-157 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 454.34 E-value: 2.27e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 2 EMPLRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEEC 81
Cdd:PRK09165 15 EPEIRELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLENDEALGEL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 82 GGISYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVE--NVIDLAERRIFNIAEN-RTTSDFE 158
Cdd:PRK09165 95 GGVQYLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVApqEQIEDAEQKLYELAETgRYEGGFQ 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 159 PMNTVLERGFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAA---LRG------ 229
Cdd:PRK09165 175 SFGTAITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAFNAAkayRREaqpdgs 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 230 -----GKSVAIFSLEMSKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCR 304
Cdd:PRK09165 255 kkavnGGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTPALSISQLRARAR 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 305 RLKLEHGIDLIVIDYLQLMSGSSG--SESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGS 382
Cdd:PRK09165 335 RLKRQHGLDLLVVDYLQLIRGSSKrsSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKRPQLSDLRESGS 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 383 IEQDADVVMFLYRDEYY--NKETEDK---------------NVAECIIAKQRNGPTGTVKLGWLGQYSKFARLDIIHQEQ 445
Cdd:PRK09165 415 IEQDADVVMFVYREEYYlkRKEPREGtpkheewqekmekvhNKAEVIIAKQRHGPTGTVKLAFESEFTRFGDLADRSQLP 494
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
5-435 |
2.97e-154 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 445.61 E-value: 2.97e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 5 LRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGI 84
Cdd:PRK08006 24 LKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGF 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 85 SYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSG-AVENVIDLAERRIFNIAENRTTSDFEP--MN 161
Cdd:PRK08006 104 AYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDPQGrTSEDLLDLAESRVFQIAESRANKDEGPknIA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 162 TVLERGFLEIERLFNNKGE-ITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEM 240
Cdd:PRK08006 184 DILDATVARIEQLFQQPHDgVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLEM 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 241 SKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAA-NIYIDDTAGVSVMEMRSKCRRLKLEH-GIDLIVID 318
Cdd:PRK08006 264 PGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGILLEKrNMYIDDSSGLTPTEVRSRARRIFREHgGLSLIMID 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 319 YLQLMSGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEY 398
Cdd:PRK08006 344 YLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEV 423
|
410 420 430
....*....|....*....|....*....|....*..
gi 1668483510 399 YNKETEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKF 435
Cdd:PRK08006 424 YHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRF 460
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
11-428 |
2.09e-153 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 441.46 E-value: 2.09e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 11 NIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGISYISEI 90
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 91 SNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESY-KNSGAVENVIDLAERRIFNIaeNRTTS---DFEPMNTVLER 166
Cdd:TIGR03600 81 SNNTPSAANISSYARIVREKAKERKLIAACQRIITLACsPDGGTAEQKVEEAQAALLAL--TMSDGqedGFVTFGEVLED 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 167 GFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLA 246
Cdd:TIGR03600 159 VVRDLDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMSAEQLG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 247 YKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEH-GIDLIVIDYLQLMSG 325
Cdd:TIGR03600 239 ERLLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKKgGLDLIVVDYIQLMAP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 326 SSGSeSRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETED 405
Cdd:TIGR03600 319 ARGR-DRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYYDAREPP 397
|
410 420
....*....|....*....|...
gi 1668483510 406 KNVAECIIAKQRNGPTGTVKLGW 428
Cdd:TIGR03600 398 AGIAELILAKNRHGPTGTVELLF 420
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
9-435 |
2.82e-153 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 442.89 E-value: 2.82e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 9 PHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGISYIS 88
Cdd:PRK08840 21 PHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFAYLA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 89 EISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSG-AVENVIDLAERRIFNIAENRTTSDFEPMN--TVLE 165
Cdd:PRK08840 101 DLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGYDPQGrTSEDLLDMAESKVFAIAEARTSENEGPQNvdSILE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 166 RGFLEIERLFNNKGE-ITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQ 244
Cdd:PRK08840 181 KTLERIELLYKTPQDgVTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVLIFSLEMPAEQ 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 245 LAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLA-AANIYIDDTAGVSVMEMRSKCRRLKLEH-GIDLIVIDYLQL 322
Cdd:PRK08840 261 LMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILMeKKNMYIDDSSGLTPTEVRSRARRIAREHgGLSMIMVDYLQL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 323 MSGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKE 402
Cdd:PRK08840 341 MRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYNPD 420
|
410 420 430
....*....|....*....|....*....|...
gi 1668483510 403 TEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKF 435
Cdd:PRK08840 421 SPLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRF 453
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
6-435 |
2.38e-148 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 431.96 E-value: 2.38e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 6 RSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGIS 85
Cdd:PRK05636 68 RQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDLERVGGAP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 86 YISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNS-GA-VENVIDLAERRIFNIAENRTTSDFEPMNTV 163
Cdd:PRK05636 148 YLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEGDeGAeIDSVIDRAQQEVFAVSQKNQSEDYAVLADI 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 164 LERGFLEIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKE 243
Cdd:PRK05636 228 LDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNKASVIFSLEMSKS 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 244 QLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLQLM 323
Cdd:PRK05636 308 EIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRSKARRLKQKHDLKLIVVDYLQLM 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 324 SGSSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKET 403
Cdd:PRK05636 388 SSGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDKDD 467
|
410 420 430
....*....|....*....|....*....|..
gi 1668483510 404 EDKNVAECIIAKQRNGPTGTVKLGWLGQYSKF 435
Cdd:PRK05636 468 ERAGEADIILAKHRGGPIDTVQVAHQLHYSRF 499
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
10-435 |
9.85e-138 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 403.62 E-value: 9.85e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 10 HNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEEcggiSYISE 89
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKIDE----EILLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 90 ISnSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSDFEPMNTVLERGFL 169
Cdd:PRK08506 81 IL-ATNPIDNIEAYVEEIKEKSIKRELLSLANTIPEQAVEEDQKSSDILDEVERELYSITNGSNSEDFKDSKEVIESTME 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 170 EIERL--FNNKgEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQyAALRGGKSVAIFSLEMSKEQLAY 247
Cdd:PRK08506 160 HIKKQkrLGNK-DIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMAL-KALNQDKGVAFFSLEMPAEQLML 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 248 KLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEH-GIDLIVIDYLQLMSGS 326
Cdd:PRK08506 238 RMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKSQHpEIGLAVIDYLQLMSGS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 327 SGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYnKETEDK 406
Cdd:PRK08506 318 GNFKDRHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDVY-KEREEK 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1668483510 407 N-----------------------VAECIIAKQRNGPTGTVKLGWLGQYSKF 435
Cdd:PRK08506 397 EkekkakkegkeerrihfqnksieEAEIIIGKNRNGPTGTVKLRFQKEFTRF 448
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
4-436 |
9.49e-121 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 360.31 E-value: 9.49e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 4 PLRSLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGG 83
Cdd:PRK06321 12 QLLSPPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 84 ISYISEISNSVPTTANLTSHVKIVKDKSILRKLIQSSTEIIEESYKNSGAVENVIDLAERRIFNIAENRTTSD------- 156
Cdd:PRK06321 92 PSYLITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEKKALEEPKDVATALDEAQNLLFKISQTTNLAQyvlvadk 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 157 FEPMNTVLERGFL----EIERLF------NNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAA 226
Cdd:PRK06321 172 LKGLTSSKDKPFLlqlqERQEAFqqsaqgDSSPMISGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNIAENFC 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 227 LRGGKSVAIFSLEMSKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRL 306
Cdd:PRK06321 252 FQNRLPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVNEMQEHTLLIDDQPGLKITDLRARARRM 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 307 KLEHGIDLIVIDYLQLMSGSS---GSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSI 383
Cdd:PRK06321 332 KESYDIQFLIIDYLQLLSGSGnlrNSESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESGSI 411
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 1668483510 384 EQDADVVMFLYRDEYYnkETEDK-NVAECIIAKQRNGPTGTVKLGWLGQYSKFA 436
Cdd:PRK06321 412 EQDSDLVMFLLRREYY--DPNDKpGTAELIVAKNRHGSIGSVPLVFEKEFARFR 463
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
11-438 |
2.75e-104 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 316.51 E-value: 2.75e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 11 NIEAEQAVIGSMFIDKAAIAEATetLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASgNLEECGGISYISEI 90
Cdd:PRK06749 5 NVEAEKTVLGSLLLDGELIKECR--LTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRVDPN-FLKGIGGMEYFIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 91 SNSVPTTANLTSHVKIVKDKSILRK---LIQSSTEIIEESYKNSGAVENVIDLAErrifnIAENRTTSDFEPMNTVLERg 167
Cdd:PRK06749 82 MDGVPTTSNFSYYEGLVRGAWKMYQagvLGHKMGERLIAEKSEKIIGETITALCE-----LEEKDCVCEFDLKDALVDL- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 168 fleIERLFNNKGEITGVPTGFPELDGKTSGFQRGDMILIAARPSMGKTTFALNIAQYAAlRGGKSVAIFSLEMSKEQLAY 247
Cdd:PRK06749 156 ---YEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAA-KSGAAVGLFSLEMSSKQLLK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 248 KLLCAEANVDMLKLRTGD--LEDKDWENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGID--LIVIDYLQLM 323
Cdd:PRK06749 232 RMASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKkiLIIVDYLQLI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 324 SGSSGSE-SRQQEVSEISRSIKALAKEMKCPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKE 402
Cdd:PRK06749 312 TGDPKHKgNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKE 391
|
410 420 430
....*....|....*....|....*....|....*.
gi 1668483510 403 TEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKFARL 438
Cdd:PRK06749 392 TMQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRFVEG 427
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
7-109 |
9.24e-38 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 132.75 E-value: 9.24e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 7 SLPHNIEAEQAVIGSMFIDKAAIAEATETLNAEDFYKDHHKVLFGAIYHLFQQDTPVDMITLIEHLRASGNLEECGGISY 86
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 1668483510 87 ISEISNSVPTTANLTSHVKIVKD 109
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
204-428 |
1.57e-25 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 103.80 E-value: 1.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 204 ILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASgPLAA 283
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKHLGKPEPLELPRDDITEEEEDDAFDN-ELGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 284 ANIYI-DDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLQ-LMSGSSGSESRqQEVSEISRSIKALAKEMKCPVIALSQLS 361
Cdd:cd19483 80 GRFFLyDHFGSLDWDNLKEKIRYMVKVLGCKVIVLDHLTiLVSGLDSSDER-KELDEIMTELAALVKELGVTIILVSHLR 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1668483510 362 RaPEQRADH----RPMLSDLRESGSIEQDADVVMFLYRDEYYNKETEdKNVAECIIAKQRNGP-TGTVKLGW 428
Cdd:cd19483 159 R-PGGGKGHeeggEVSESDLRGSSAIAQLSDYVIGLERNKQADDPVE-RNTTRVRVLKNRFTGeTGIAGTLY 228
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
382-438 |
9.79e-22 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 98.28 E-value: 9.79e-22
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1668483510 382 SIEQDADVVMFLYRDEYYNKETEDKNVAECIIAKQRNGPTGTVKLGWLGQYSKFARL 438
Cdd:PRK07773 827 SIEQDADVVILLYRPDYYDRDDPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANL 883
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
184-401 |
6.21e-15 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 73.80 E-value: 6.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 184 VPTGFPELDGKTS-GFQRGDMILIAARPSMGKTTFALNIAqYAALRGGKSVAIFSLEMSKEQLAykllcaeANVDMLKLR 262
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFL-AEGLRRGEKGLYVSFEESPEQLL-------RRAESLGLD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 263 TGDLEDKDweniakasgplaaaNIYIDDTA----GVSVMEMRSKCRRLKLEHGIDLIVID----YLQLMsgssgseSRQQ 334
Cdd:COG0467 74 LEEYIESG--------------LLRIIDLSpeelGLDLEELLARLREAVEEFGAKRVVIDslsgLLLAL-------PDPE 132
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1668483510 335 EVSEISRSIKALAKEMKCPVIALSQLsrapeqradhrPMLSDLRESGSIEQDADVVMFLYRDEYYNK 401
Cdd:COG0467 133 RLREFLHRLLRYLKKRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILLRYVELGGE 188
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
201-378 |
3.85e-13 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 68.91 E-value: 3.85e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 201 GDMILIAARPSMGKTTFALNIAqYAALRGGKSVAIFSLEMSKEQLAYKlLCA-----EANVDMLKLRTGDledkdwenia 275
Cdd:PRK05973 64 GDLVLLGARPGHGKTLLGLELA-VEAMKSGRTGVFFTLEYTEQDVRDR-LRAlgadrAQFADLFEFDTSD---------- 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 276 kasgplAAANIYIddtagvsvmemrskCRRLKLEHGIDLIVIDYLQLMsgssgSESRQQ-EVSEISRSIKALAKEMKCPV 354
Cdd:PRK05973 132 ------AICADYI--------------IARLASAPRGTLVVIDYLQLL-----DQRREKpDLSVQVRALKSFARERGLII 186
|
170 180
....*....|....*....|....
gi 1668483510 355 IALSQLSRAPEQRADHRPMLSDLR 378
Cdd:PRK05973 187 VFISQIDRSFDPSAKPLPDIRDVR 210
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
197-419 |
1.55e-11 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 65.85 E-value: 1.55e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 197 GFQRGDMILIAARPSMGKTTFALNIAQyAALRGGKSVAIFSLEMSKEQLAYKLLCAEANVDMLKLRtgDLEDKDWENI-- 274
Cdd:PHA02542 186 GAERKTLNVLLAGVNVGKSLGLCSLAA-DYLQQGYNVLYISMEMAEEVIAKRIDANLLDVSLDDID--DLSKAEYKAKme 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 275 ---AKASGPLAaanIYIDDTAGVSVMEMRSKCRRLKLEHGI--DLIVIDYLQLMSGS---SGSESRQQEVSEISRSIKAL 346
Cdd:PHA02542 263 klrSKTQGKLI---IKQYPTGGAHAGHFRALLNELKLKKNFkpDVIIVDYLGICASSrlrVSSENSYTYVKAIAEELRGL 339
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1668483510 347 AKEMKCPVIALSQLSRAPEQRADhrPMLSDLRESGSIEQDADVVMFLYRDEyynkETEDKNVAECIIAKQRNG 419
Cdd:PHA02542 340 AVEHDVVVWTAAQTTRSGWDSSD--VDMSDTAESAGLPATADFMLAVIETE----ELAQMGQQLVKQLKSRYG 406
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
200-426 |
1.11e-10 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 62.61 E-value: 1.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 200 RGDMILIAARPSMGKTTFALNIAqYAALRGGK---------SVAIFSLEMSKEQLA--YKLLCA---------EANVDML 259
Cdd:COG3598 12 EGGVTLLAGPPGTGKSFLALQLA-AAVAAGGPwlgrrvppgKVLYLAAEDDRGELRrrLKALGAdlglpfadlDGRLRLL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 260 KLRTGDLEDKDWENIAKAsgplaaaniyIDdtagvsvmemrskcrrlklEHGIDLIVIDYLQLMSGssGSESRQQEVSEI 339
Cdd:COG3598 91 SLAGDLDDTDDLEALERA----------IE-------------------EEGPDLVVIDPLARVFG--GDENDAEEMRAF 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 340 SRSIKALAKEMKCPVIAL-----SQLSRAPEQRAdhrpmlsdlRESGSIEQDADVVMFLYRDeyynketEDKNVAECIIA 414
Cdd:COG3598 140 LNPLDRLAERTGAAVLLVhhtgkGGAGKDSGDRA---------RGSSALRGAARSVLVLSRE-------KGEDLRVLTRA 203
|
250
....*....|..
gi 1668483510 415 KQRNGPTGTVKL 426
Cdd:COG3598 204 KSNYGPEIALRW 215
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
200-365 |
2.38e-09 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 56.62 E-value: 2.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 200 RGDMILIAARPSMGKTTFALNIAqyAALRGGKSVaiFSLEMSKEQLAYKLLCAEANVDMLKLR----TGDLEDKDWENIA 275
Cdd:pfam13481 32 AGGLGLLAGAPGTGKTTLALDLA--AAVATGKPW--LGGPRVPEQGKVLYVSAEGPADELRRRlraaGADLDLPARLLFL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 276 KASGPLaaaNIYIDDTAGVSVME-MRSKCRRLKLEHGIDLIVIDYLQLMSGssGSESRQQEVSEISRSIKALAKEMKCPV 354
Cdd:pfam13481 108 SLVESL---PLFFLDRGGPLLDAdVDALEAALEEVEDPDLVVIDPLARALG--GDENSNSDVGRLVKALDRLARRTGATV 182
|
170
....*....|.
gi 1668483510 355 IALSQLSRAPE 365
Cdd:pfam13481 183 LLVHHVGKDGA 193
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
184-397 |
5.99e-07 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 49.95 E-value: 5.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 184 VPTGFPELD----GktsGFQRGDMILIAARPSMGKTTFALNIAqYAALRGGKSVAIFSLEMSKEQLAYKllCAEANVDml 259
Cdd:cd01124 1 VKTGIPGLDellgG---GIPKGSVTLLTGGPGTGKTLFGLQFL-YAGAKNGEPGLFFTFEESPERLLRN--AKSFGWD-- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 260 klrtgdledkdwENIAKASGPLAAANIYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLqlmSGSSGSESRQQEVSEI 339
Cdd:cd01124 73 ------------FDEMEDEGKLIIVDAPPTEAGRFSLDELLSRILSIIKSFKAKRVVIDSL---SGLRRAKEDQMRARRI 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1668483510 340 SRSIKALAKEMKCPVIALSQLsrapeqradHRPMLSDLRESGSIEQDADVVMFLYRDE 397
Cdd:cd01124 138 VIALLNELRAAGVTTIFTSEM---------RSFLSSESAGGGDVSFIVDGVILLRYVE 186
|
|
| KaiC_C |
cd19484 |
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ... |
184-245 |
1.04e-06 |
|
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410892 [Multi-domain] Cd Length: 218 Bit Score: 49.25 E-value: 1.04e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1668483510 184 VPTGFPELDG--KTSGFQRGDMILIAARPSMGKTTFALNIAQyAALRGGKSVAIFSLEMSKEQL 245
Cdd:cd19484 1 ISTGIPRLDAmlGGGGFFRGSSILVSGATGTGKTLLAASFAD-AACRRGERCLYFAFEESPAQL 63
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
184-355 |
1.36e-06 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 49.45 E-value: 1.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 184 VPTGFPELD----GktsGFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIfSLEMSKEQLAYKllcaeanVDML 259
Cdd:cd01121 64 ISTGIGELDrvlgG---GLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYV-SGEESLSQIKLR-------AERL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 260 KLRTGDLE---DKDWENIakasgpLAAANiyiddtagvsvmemrskcrrlklEHGIDLIVID-----YLQLMSGSSGSES 331
Cdd:cd01121 133 GLGSDNLYllaETNLEAI------LAEIE-----------------------ELKPSLVVIDsiqtvYSPELTSSPGSVS 183
|
170 180
....*....|....*....|....
gi 1668483510 332 rqqEVSEISRSIKALAKEMKCPVI 355
Cdd:cd01121 184 ---QVRECAAELLRLAKETGIPVF 204
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
184-245 |
1.02e-05 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 47.57 E-value: 1.02e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1668483510 184 VPTGFPELD---GKtsGFQRGDMILIAARPSMGKTTFALNIAQyAALRGGKSVAIFSLEMSKEQL 245
Cdd:PRK09302 255 ISSGVPDLDemlGG--GFFRGSIILVSGATGTGKTLLASKFAE-AACRRGERCLLFAFEESRAQL 316
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
201-360 |
2.55e-05 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 44.65 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 201 GDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIfslemskeqlaykllCAEANVDMLKLRTGDLEDK-DWENIAKASG 279
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWI---------------DTEGAFPPSRLVQILEASPsSELELAEALS 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 280 PLAAANIYIDDTAGVSVMemrSKCRRLKLEHGIDLIVID---------YLQLMSGSSGSESRQQEVSEISRSIKALAKEM 350
Cdd:cd01393 66 RLLYFRPPDTLAHLLALD---SLPESLFPPPNTSLVVVDsvsalfrkaFPRGGDGDSSSSLRARLLSQLARALQKLAAQF 142
|
170
....*....|
gi 1668483510 351 KCPVIALSQL 360
Cdd:cd01393 143 NLAVVVTNQV 152
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
184-361 |
5.75e-05 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 44.16 E-value: 5.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 184 VPTGFPELDGKTS-GFQRGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAYkllcaeaNVDMLKLR 262
Cdd:pfam06745 1 VKTGIPGLDEILKgGFPEGRVVLITGGPGTGKTIFGLQFLYNGALKYGEPGVFVTLEEPPEDLRE-------NARSFGWD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 263 TGDLEDKDWENIAKASGPLAAaniYIDDTAGVSVMEMRSKCRRLKLEHGIDLIVIDYLqlmsGSSGSESRQQEVSEISRS 342
Cdd:pfam06745 74 LEKLEEEGKLAIIDASTSGIG---IAEVEDRFDLEELIERLREAIREIGAKRVVIDSI----TTLFYLLKPAVAREILRR 146
|
170
....*....|....*....
gi 1668483510 343 IKALAKEMKCPVIALSQLS 361
Cdd:pfam06745 147 LKRVLKGLGVTAIFTSEKP 165
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
204-384 |
1.50e-04 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 41.33 E-value: 1.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 204 ILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLaykllcaeanvdmlklrtgdledkdweniakasgplaa 283
Cdd:cd01120 1 ILITGPPGSGKTTLLLQFAEQALLSDEPVIFISFLDTILEAI-------------------------------------- 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 284 aniyiddtagvsvmemrskcRRLKLEHGIDLIVIDYLQLMSGSSGSEsRQQEVSEISRSIKALAKEMKCPVIALSQLSRA 363
Cdd:cd01120 43 --------------------EDLIEEKKLDIIIIDSLSSLARASQGD-RSSELLEDLAKLLRAARNTGITVIATIHSDKF 101
|
170 180
....*....|....*....|.
gi 1668483510 364 PEqraDHRPMLSDLRESGSIE 384
Cdd:cd01120 102 DI---DRGGSSNDERLLKSLR 119
|
|
| DDXDc_reverse_gyrase |
cd17924 |
DDXD-box helicase domain of reverse gyrase; Reverse gyrase modifies the topological state of ... |
200-249 |
7.33e-04 |
|
DDXD-box helicase domain of reverse gyrase; Reverse gyrase modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. Reverse gyrase belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350682 [Multi-domain] Cd Length: 189 Bit Score: 40.39 E-value: 7.33e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1668483510 200 RGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIFSLEMSKEQLAYKL 249
Cdd:cd17924 31 RGKSFAIIAPTGVGKTTFGLATSLYLASKGKRSYLIFPTKSLVKQAYERL 80
|
|
| Twinkle_C |
cd01122 |
C-terminal domain of Twinkle; Twinkle ( T7 gp4-like protein with intramitochondrial nucleoid ... |
170-329 |
1.23e-03 |
|
C-terminal domain of Twinkle; Twinkle ( T7 gp4-like protein with intramitochondrial nucleoid localization, also known as C10orf2, PEO1, SCA8, ATXN8, IOSCA, PEOA3 or SANDO) is a homohexameric DNA helicases which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. Mutations in the human gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. This group also contains viral GP4-like and related bacterial helicases.
Pssm-ID: 410867 Cd Length: 266 Bit Score: 40.30 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 170 EIERLFNNKGEITGVP-TGFPELDGKTSGFQRGDMILIAARPSMGKTTFalnIAQYA---------ALRGgksvaifSLE 239
Cdd:cd01122 11 LVYEELLNSEQVAGVQwKRFPSLNKLLKGHRRGELTIFTGPTGSGKTTF---LSEYSldlcmqgvnTLWG-------SFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 240 MSKEQLAYKLLCAEANVDMLKLRTgdledkDWENIAKA--SGPLAAANIY----IDDTagVSVMEmrskcrRLKLEHGID 313
Cdd:cd01122 81 IKNVRLAKTMLTQFAGKNLEDNLR------EFDEWADKfeLLPMYFMKFHgstdIDEV--LDAME------HAVYVYDIQ 146
|
170
....*....|....*.
gi 1668483510 314 LIVIDYLQLMSGSSGS 329
Cdd:cd01122 147 HIVIDNLQFMMGTQAS 162
|
|
| KaiC-like_C |
cd19487 |
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
184-245 |
1.54e-03 |
|
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410895 [Multi-domain] Cd Length: 219 Bit Score: 39.98 E-value: 1.54e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1668483510 184 VPTGFPELD----GktsGFQRGDMILIAARPSMGKTTFALNIAQYAALRgGKSVAIFSLEMSKEQL 245
Cdd:cd19487 1 VSSGVPELDellgG---GLERGTSTLLIGPAGVGKSTLALQFAKAAAAR-GERSVLFSFDESIGTL 62
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
200-368 |
3.64e-03 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 37.74 E-value: 3.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 200 RGDMILIAARPSMGKTTFALNIAQYAALRGGKSVAIfSLEMSKEQLAYKLLCAEanvdmlklrtgdledkdweniakasg 279
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYI-DGEDILEEVLDQLLLII-------------------------- 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 280 plaaanIYIDDTAGVSVMEMRSKCRRLKlEHGIDLIVIDYLQLMSGSSGSESRQQEvsEISRSIKALAKEMKCPVIALSQ 359
Cdd:smart00382 54 ------VGGKKASGSGELRLRLALALAR-KLKPDVLILDEITSLLDAEQEALLLLL--EELRLLLLLKSEKNLTVILTTN 124
|
....*....
gi 1668483510 360 LSRAPEQRA 368
Cdd:smart00382 125 DEKDLGPAL 133
|
|
| ParA |
COG1192 |
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein ... |
213-318 |
4.57e-03 |
|
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ [Cell cycle control, cell division, chromosome partitioning, Cell motility];
Pssm-ID: 440805 [Multi-domain] Cd Length: 253 Bit Score: 38.69 E-value: 4.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 213 GKTTFALNIAQYAALRGGKSVAI---------FSLEMSKEQL---AYKLLCAEANVDMLKLRTgdledkDWEN--IAKAS 278
Cdd:COG1192 14 GKTTTAVNLAAALARRGKRVLLIdldpqgnltSGLGLDPDDLdptLYDLLLDDAPLEDAIVPT------EIPGldLIPAN 87
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1668483510 279 GPLAAANIYIddtagVSVMEMRSKCRRL--KLEHGIDLIVID 318
Cdd:COG1192 88 IDLAGAEIEL-----VSRPGRELRLKRAlaPLADDYDYILID 124
|
|
| RepA_RSF1010_like |
cd01125 |
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family ... |
205-417 |
5.50e-03 |
|
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family includes the homo-hexameric replicative helicase RepA encoded by plasmid RSF1010. RSF1010 is found in most Gram-negative bacteria and some Gram-positive bacteria . The RepA protein of Plasmid RSF1010 is a 5'-3' DNA helicase which can utilize ATP, dATP, GTP and dGTP (and CTP and dCTP to a lesser extent).
Pssm-ID: 410870 Cd Length: 238 Bit Score: 38.13 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 205 LIAARPSMGKTTFALNIAqyAALRGGKSVAIFSlemSKEQLAYKLLCAEANVDMLKLRTGDLEDKDWENIAKASGPLAAA 284
Cdd:cd01125 5 MLVGPPGSGKSFLALDLA--VAVATGRDWLGER---RVKQGRVVYLAAEDPRDGLRRRLKAIGAHLGDEDAALAENLVIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1668483510 285 NIYIDDtagVSVMEMRSKCRRLKLEH-GIDLIVIDYLQLMSGsSGSESRQQEVSEISRSIKALAKEMKCPVIALSQLSRA 363
Cdd:cd01125 80 NLRGKP---VSIDAEAPELERIIEELeGVRLIIIDTLARVLH-GGDENDAADMGAFVAGLDRIARETGAAVLLVHHTGKD 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1668483510 364 PEqradhRPMLSDLRESGSIEQDADVVMFLYRDEyynkETEDKNVAECIIAKQR 417
Cdd:cd01125 156 AA-----GDSQQAARGSSALRGAADAEINLSKMD----ATEAEKVGLDKDLRRR 200
|
|
| |
