|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
152-455 |
1.37e-53 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 183.46 E-value: 1.37e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 152 FIGALADLYGRALSAQENERINAELERANQHLEErVVERTRTLEKTLSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTP 231
Cdd:COG4191 78 LLLLLGLLLLLLLEALLLLLLAALDAEENAELEE-LERDITELERAEEELRELQEQLVQSEKLAALGELAAGIAHEINNP 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 232 IGIAVTANSSAKDKLSEvdkliqsnTLTKAALIESINHLNEcfkisftNLERAAKLISDFKQTAvDQSSLDLLETNIKDY 311
Cdd:COG4191 157 LAAILGNAELLRRRLED--------EPDPEELREALERILE-------GAERAAEIVRSLRAFS-RRDEEEREPVDLNEL 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 312 LENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLVNNSCvHGFVGRQDNQINISVNIDEAQGVylLCYKD 390
Cdd:COG4191 221 IDEALELLRPRLKARGIEVELDLPPDLPPVLGdPGQLEQVLLNLLINAI-DAMEEGEGGRITISTRREGDYVV--ISVRD 297
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1675083294 391 NGHGMDTETLHKVFEPFFTTKRgsggsglGMS-------IVYNLATQaLQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:COG4191 298 NGPGIPPEVLERIFEPFFTTKP-------VGKgtglglsISYGIVEK-HGGRIEVESEPGGGTTFTITLPLA 361
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
152-454 |
2.63e-25 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 105.76 E-value: 2.63e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 152 FIGALADLYGRALSAQENERINAELERANQHLEERVVERTRTLEKTLSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTP 231
Cdd:COG0642 45 LLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTP 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 232 IGIAVTANSSAKDKLSEVDKliqsntltkaALIESINHlnecfkisftNLERAAKLISDFKQTA---VDQSSLDLLETNI 308
Cdd:COG0642 125 LTAIRGYLELLLEELDEEQR----------EYLETILR----------SADRLLRLINDLLDLSrleAGKLELEPEPVDL 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 309 KDYLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLVNNSCVHGFVGRQdnqinISVNIDEAQGVYLLC 387
Cdd:COG0642 185 AELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGdPDRLRQVLLNLLSNAIKYTPEGGT-----VTVSVRREGDRVRIS 259
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1675083294 388 YKDNGHGMDTETLHKVFEPFFTTKRgsggsGLGMS-------IVYNLAtQALQGEVSAASSPSNGMTVNFKLPI 454
Cdd:COG0642 260 VEDTGPGIPPEDLERIFEPFFRTDP-----SRRGGgtglglaIVKRIV-ELHGGTIEVESEPGKGTTFTVTLPL 327
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
129-454 |
1.97e-22 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 98.88 E-value: 1.97e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 129 KMIGIFCCEHIGseRHWTEDECSFigALADLYGRALSAQENERINAELERANQHLEERVVERTRTLEKTLSELTEmqekL 208
Cdd:COG5000 121 RLLGIPLEELIG--KPLEELLPEL--DLAELLREALERGWQEEIELTRDGRRTLLVRASPLRDDGYVIVFDDITE----L 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 209 IEAEKMASLGNLVAGIAHEVNTPIG-IAVTAnSSAKDKLSEVdkliqsntltkaaLIESINHLNECFKISFTNLERAAKL 287
Cdd:COG5000 193 LRAERLAAWGELARRIAHEIKNPLTpIQLSA-ERLRRKLADK-------------LEEDREDLERALDTIIRQVDRLKRI 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 288 ISDFKQTAVdQSSLDLLETNIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLVNNScvhgfvgR 366
Cdd:COG5000 259 VDEFLDFAR-LPEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLAdRDQLEQVLINLLKNA-------I 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 367 Q--DNQINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTKRgsggsglgmsIVYNLAtQALQGEVSAASSPSN 444
Cdd:COG5000 331 EaiEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFTTKPkgtg--lglaIVKKIV-EEHGGTIELESRPGG 407
|
330
....*....|
gi 1675083294 445 GMTVNFKLPI 454
Cdd:COG5000 408 GTTFTIRLPL 417
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
193-455 |
8.09e-22 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 96.39 E-value: 8.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 193 TLEKTLSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPIGIavtanssakdkLSEVDKLIQSNTLTKaaliesinHLNE 272
Cdd:COG5807 123 TVYRDITKRKEAEDKLLRSEKLSVAGELAAGIAHEIRNPLTS-----------IKGFLQLLQESREDS--------EREE 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 273 CFKISFTNLERAAKLISDFKQTAVDQSSlDLLETNIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQII 351
Cdd:COG5807 184 YFNIIISEIDRINTIITELLVLSKPKKF-NFKKLNLNDVLEDVIALLSTEAILKNISIKYDLADDEPVINGdKNQLKQVF 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 352 MNLVNNScVHGFvgRQDNQINISVNiDEAQGVYLlCYKDNGHGMDTETLHKVFEPFFTTKrgSGGSGLGMSIVYNLAtQA 431
Cdd:COG5807 263 INLIKNA-IEAM--ETGGNITIKTY-VEGDFVVI-SVKDEGIGIPEEVLEKIGEPFFTTK--EEGTGLGLSICKKII-EE 334
|
250 260
....*....|....*....|....
gi 1675083294 432 LQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:COG5807 335 HNGTIEVESKPGKGTTFTIYLPLY 358
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
198-455 |
8.21e-22 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 96.45 E-value: 8.21e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 198 LSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPIGiAVTANSSakdklsevdkLIQSNtLTKAALIESINHLNEcfkis 277
Cdd:COG3852 116 ITERKRLERELRRAEKLAAVGELAAGLAHEIRNPLT-GIRGAAQ----------LLERE-LPDDELREYTQLIIE----- 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 278 ftNLERAAKLISDFKQTAvDQSSLDLLETNIKDYLENILhSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLVN 356
Cdd:COG3852 179 --EADRLNNLVDRLLSFS-RPRPPEREPVNLHEVLERVL-ELLRAEAPKNIRIVRDYDPSLPEVLGdPDQLIQVLLNLVR 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 357 NSC------------------VHGFVGRQDNQINISVnideaqgvyllcyKDNGHGMDTETLHKVFEPFFTTKrgsggsg 418
Cdd:COG3852 255 NAAeampeggtitirtrverqVTLGGLRPRLYVRIEV-------------IDNGPGIPEEILDRIFEPFFTTK------- 314
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1675083294 419 lgMS-------IVYNLATQaLQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:COG3852 315 --EKgtglglaIVQKIVEQ-HGGTIEVESEPGKGTTFRIYLPLE 355
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
200-454 |
9.36e-22 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 93.82 E-value: 9.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 200 ELTEMQEKLIEAEKMASlgNLVAGIAHEVNTPIGIAVTANSSAKDKLSEVDKLIQSntltkaaLIESINHlnecfkisft 279
Cdd:COG2205 1 ELEEALEELEELERLKS--EFLANVSHELRTPLTSILGAAELLLDEEDLSPEERRE-------LLEIIRE---------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 280 NLERAAKLISDFKQTAVDQS---SLDLLETNIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLV 355
Cdd:COG2205 62 SAERLLRLIEDLLDLSRLESgklSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYAdPELLEQVLANLL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 356 NNSCVHGfvgrqDNQINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGM--SIVYNLAtQALQ 433
Cdd:COG2205 142 DNAIKYS-----PPGGTITISARREGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRGEGGTGLglAIVKRIV-EAHG 215
|
250 260
....*....|....*....|.
gi 1675083294 434 GEVSAASSPSNGMTVNFKLPI 454
Cdd:COG2205 216 GTIWVESEPGGGTTFTVTLPL 236
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
196-411 |
4.44e-20 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 92.49 E-value: 4.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 196 KTLSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPigiavtanssakdkLSEVDKLIQsntLTKAALIESinhlNECFK 275
Cdd:COG5805 266 RDITEKKEAEELMARSEKLSIAGQLAAGIAHEIRNP--------------LTSIKGFLQ---LLQPGIEDK----EEYFD 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 276 ISFTNLERAAKLISDFKQTAVDQSsLDLLETNIKdyleNILHSLMPLTRS----HNVSVNVNCVD-DFELITVPGALSQI 350
Cdd:COG5805 325 IMLSELDRIESIISEFLALAKPQA-VNKEKENIN----ELIQDVVTLLETeailHNIQIRLELLDeDPFIYCDENQIKQV 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1675083294 351 IMNLVNNScvhgfVGRQDNQINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTK 411
Cdd:COG5805 400 FINLIKNA-----IEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTK 455
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
203-411 |
1.19e-18 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 87.62 E-value: 1.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 203 EMQEKLIEAEKMASLGNLVAGIAHEVNTPIgiavtanSSAKDKLsevdKLIQSNTLTKAALIESInhlnecfKISFTNLE 282
Cdd:COG5806 187 LLRKELQRAEKLEVVSELAASIAHEVRNPL-------TVVRGFI----QLLQEPELSDEKRKQYI-------RIALEELD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 283 RAAKLISDFKQTAVDQSslDLLET-NIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITVPGALSQIIMNLVNN---S 358
Cdd:COG5806 249 RAEAIITDYLTFAKPQP--EKLEKiDVSEELEHVIDVLSPYANMNNVEIQTELEPGLYIEGDRQKLQQCLINIIKNgieA 326
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1675083294 359 CVHGFVgrqdnqINISVNIDEAQgvYLLCYKDNGHGMDTETLHKVFEPFFTTK 411
Cdd:COG5806 327 MPNGGT------LTIDVSIDKNK--VIISIKDTGVGMTKEQLERLGEPYFSTK 371
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
152-455 |
2.66e-15 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 77.29 E-value: 2.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 152 FIGALADLYGRALSAQENERINAELERANQHLEERVVERTRTLEKTLSELTEMQEKLIEAEKMASlgNLVAGIAHEVNTP 231
Cdd:COG5002 102 LILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRR--EFVANVSHELRTP 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 232 I----GIAVTANSSAKDKLSEVDKLIQsntltkaaliesinhlnecfkISFTNLERAAKLISDFKQTA-VDQSSLDLL-- 304
Cdd:COG5002 180 LtsirGYLELLLDGAADDPEERREYLE---------------------IILEEAERLSRLVNDLLDLSrLESGELKLEke 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 305 ETNIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLVNNSCVHGfvgrqDNQINISVNIDEAQGV 383
Cdd:COG5002 239 PVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGdPDRLEQVLTNLLDNAIKYT-----PEGGTITVSLREEDDQ 313
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1675083294 384 YLLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGM----SIVYNLAtQALQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:COG5002 314 VRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTglglAIVKHIV-EAHGGRIWVESEPGKGTTFTITLPLA 388
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
196-455 |
8.11e-15 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 76.55 E-value: 8.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 196 KTLSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPI----GIAVTANSSAKDKLSEvdklIQSNTLTKAalIESINHLN 271
Cdd:PRK11360 369 SDLTERKRLQRRVARQERLAALGELVAGVAHEIRNPLtairGYVQIWRQQTSDPPSQ----EYLSVVLRE--VDRLNKVI 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 272 EcfkisftnleraaKLIsDF---KQTAVDQSSLDLLetnIKDYLENILHSlmpltrSHNVSVNVNCVDDFELITV---PG 345
Cdd:PRK11360 443 D-------------QLL-EFsrpRESQWQPVSLNAL---VEEVLQLFQTA------GVQARVDFETELDNELPPIwadPE 499
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 346 ALSQIIMNLVNNScVHGFVGRQDNQINISVNIDEAQGVYLlcyKDNGHGMDTETLHKVFEPFFTTKRGSG--GSGLGMSI 423
Cdd:PRK11360 500 LLKQVLLNILINA-VQAISARGKIRIRTWQYSDGQVAVSI---EDNGCGIDPELLKKIFDPFFTTKAKGTglGLALSQRI 575
|
250 260 270
....*....|....*....|....*....|..
gi 1675083294 424 VynlatQALQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:PRK11360 576 I-----NAHGGDIEVESEPGVGTTFTLYLPIN 602
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
344-455 |
9.37e-14 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 67.29 E-value: 9.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 344 PGALSQIIMNLVNNSCVHGFVGrqdnqINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLG--- 420
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTPEG-----GRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTglg 77
|
90 100 110
....*....|....*....|....*....|....*
gi 1675083294 421 MSIVYNLAtQALQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:smart00387 78 LSIVKKLV-ELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
203-455 |
1.73e-13 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 72.09 E-value: 1.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 203 EMQEKL---IEAEKMASLGNLVAGIAHEVNTPigiavtanssakdkLSEVDKLIQSNTLTKAALIEsinhlNECFKISFT 279
Cdd:COG5808 224 TLLERViqeINTQKLELIGTFAASTAHEIRNP--------------LTSIKGFIQLLQEKYPELED-----QKYFDIIQE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 280 NLERAAKLISDF----KQTAVDQSSLDLletniKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNL 354
Cdd:COG5808 285 EIQRINQIVSEFlvlgKPTAKKLELDDL-----NELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCdKDRIKQVLLNL 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 355 VNNSCVhgfVGRQDNQINISVNIDEAQGVylLCYKDNGHGMDTETLHKVFEPFFTTKrgSGGSGLGMSIVYNLAtQALQG 434
Cdd:COG5808 360 IKNAIE---AMKEGGKLTISIENDDEKAV--IEVIDNGEGIPEDIIDEIFEPFVTTK--EGGTGLGLSVCKRIV-EMHGG 431
|
250 260
....*....|....*....|.
gi 1675083294 435 EVSAASSPSNGMTVNFKLPIK 455
Cdd:COG5808 432 EIDIESEEGKGTTFTIRLPLK 452
|
|
| GAF |
COG2203 |
GAF domain [Signal transduction mechanisms]; |
2-217 |
2.30e-13 |
|
GAF domain [Signal transduction mechanisms];
Pssm-ID: 441805 [Multi-domain] Cd Length: 712 Bit Score: 72.15 E-value: 2.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 2 RQQLVQLLYGVS--ISSDLDsgnVELAERLILNAVLDGLEIGRAGIWLLNKENTAIECRLLLDRENGKEIQmlvLPRDAY 79
Cdd:COG2203 188 ELERLALLNEISqaLRSALD---LEELLQRILELAGELLGADRGAILLVDEDGGELELVAAPGLPEEELGR---LPLGEG 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 80 PdYFKALDTQRTITAVDAHTDPATYEFSESYLTPLNIGAMLDAPIRYKGKMIGIFCCEHiGSERHWTEDECSFIGALADL 159
Cdd:COG2203 262 L-AGRALRTGEPVVVNDASTDPRFAPSLRELLLALGIRSLLCVPLLVDGRLIGVLALYS-KEPRAFTEEDLELLEALADQ 339
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1675083294 160 YGRALsaqENERINAELERANQHLEERVVERTRTLEKTLSELTEMQEKLIEAEKMASL 217
Cdd:COG2203 340 AAIAI---ERARLYEALEAALAALLQELALLRLLLDLELTLLRLRQLLLELLLALLLL 394
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
198-456 |
2.05e-12 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 68.85 E-value: 2.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 198 LSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPIgiavtanSSAKDKLsevdKLIQSNTLTKAALIesinhlnecFKIS 277
Cdd:COG5809 251 ITERKKLEELLRKSEKLSVVGELAAGIAHEIRNPL-------TSLKGFI----QLLKDTIDEEQKTY---------LDIM 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 278 FTNLERAAKLISDF----KQTAVDQSsldllETNIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELIT-VPGALSQIIM 352
Cdd:COG5809 311 LSELDRIESIISEFlvlaKPQAIKYE-----PKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDILgDENQLKQVFI 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 353 NLVNNScvhgfVGRQDNQINISVNI-DEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTKrgSGGSGLGMSIVYNLATQa 431
Cdd:COG5809 386 NLLKNA-----IEAMPEGGNITIETkAEDDDKVVISVTDEGCGIPEERLKKLGEPFYTTK--EKGTGLGLMVSYKIIEE- 457
|
250 260
....*....|....*....|....*
gi 1675083294 432 LQGEVSAASSPSNGMTVNFKLPIKL 456
Cdd:COG5809 458 HGGKITVESEVGKGTTFSITLPIKL 482
|
|
| GAF |
pfam01590 |
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl ... |
28-164 |
5.67e-12 |
|
GAF domain; This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54. This domain can bind biliverdine and phycocyanobilin (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 460259 [Multi-domain] Cd Length: 133 Bit Score: 62.88 E-value: 5.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 28 RLILNAVLDGLEIGRAGIWLLNKENtaiecrlLLDRENGKEIQMLVLPRDAYPDYFKALDTQRTITAVDAHTDPAtYEFS 107
Cdd:pfam01590 7 QTILEELRELLGADRCALYLPDADG-------LEYLPPGARWLKAAGLEIPPGTGVTVLRTGRPLVVPDAAGDPR-FLDP 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1675083294 108 ESYLTPLNIGAMLDAPIRYKGKMIGIFCCEHigSERHWTEDECSFIGALADLYGRAL 164
Cdd:pfam01590 79 LLLLRNFGIRSLLAVPIIDDGELLGVLVLHH--PRPPFTEEELELLEVLADQVAIAL 133
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
185-455 |
1.07e-11 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 66.35 E-value: 1.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 185 ERVVERTRTLEKtlseltEMQEKlieaEKMASLGNLVAGIAHEVNTPI----GIAVTANSSAKDKlSEVDKLIQsntltk 260
Cdd:PRK10364 215 RRYLRSRQLLQD------EMKRK----EKLVALGHLAAGVAHEIRNPLssikGLAKYFAERAPAG-GEAHQLAQ------ 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 261 aALIESINHLNecfkisftnleraaKLISDFKQTaVDQSSLDLLETNIKDYLENILHSLMPLTRSHNVSVNVNCVDDFEL 340
Cdd:PRK10364 278 -VMAKEADRLN--------------RVVSELLEL-VKPTHLALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 341 ITV-PGALSQIIMNLVNNScVHGfVGRQDNqinISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTKrgSGGSGL 419
Cdd:PRK10364 342 IQAdPDRLTQVLLNLYLNA-IQA-IGQHGV---ISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK--AEGTGL 414
|
250 260 270
....*....|....*....|....*....|....*.
gi 1675083294 420 GMSIVYNLATQAlQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:PRK10364 415 GLAVVHNIVEQH-GGTIQVASQEGKGATFTLWLPVN 449
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-454 |
3.96e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 59.74 E-value: 3.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 344 PGALSQIIMNLVNNScVHGFVGRqdNQINISVNIDEAQgvYLLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGMSI 423
Cdd:cd16943 1 PSQLNQVLLNLLVNA-AQAMEGR--GRITIRTWAHVDQ--VLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSL 75
|
90 100 110
....*....|....*....|....*....|.
gi 1675083294 424 VYNLaTQALQGEVSAASSPSNGMTVNFKLPI 454
Cdd:cd16943 76 SYRI-IQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
174-411 |
1.16e-10 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 63.55 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 174 AELERANQHLEERVVERTRTLEktlsELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPIGIAVTANSSAKdklsevDKLI 253
Cdd:COG4192 394 DQAIEKTQELETEIEERKRIEK----NLRQTQDELIQAAKMAVVGQTMTSLAHELNQPLNAMSMYLFSAK------KALE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 254 QSNTLTKAALIESINHLnecfkisftnLERAAKLISDFKQTAvDQSSLDLLETNIKDYLENILhsLMPLTRSHNVSVNVN 333
Cdd:COG4192 464 QENYAQLPTSLDKIEGL----------IERMDKIIKSLRQFS-RKSDTPLQPVDLRQVIEQAW--ELVESRAKPQQITLH 530
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1675083294 334 CVDDFELITVPGALSQIIMNLVNNSCvhgfvGRQDNQINISVNIDEAQGVYLLCYKDNGHGMDteTLHKVFEPFFTTK 411
Cdd:COG4192 531 IPDDLMVQGDQVLLEQVLVNLLVNAL-----DAVATQPQISVDLLSNAENLRVAISDNGNGWP--LVDKLFTPFTTTK 601
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
342-455 |
1.75e-10 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 57.76 E-value: 1.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 342 TVPGALSQIIMNLVNNSCVHGFVGRQdnqinISVNIDEAQGVYLLCyKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGM 421
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGE-----ITVTLSEGGELTLTV-EDNGIGIPPEDLPRIFEPFSTADKRGGGGTGLG 74
|
90 100 110
....*....|....*....|....*....|....
gi 1675083294 422 SIVYNLATQALQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:pfam02518 75 LSIVRKLVELLGGTITVESEPGGGTTVTLTLPLA 108
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
188-454 |
6.18e-10 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 61.62 E-value: 6.18e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 188 VERTRtLEktlSELTEMQEKLIEAEKMASLGNLVAGIAHEVNTPIGiAVTANSS-AKDKLSevdkliqsntlTKAALIES 266
Cdd:PRK13837 425 IERRR-LE---TERDALERRLEHARRLEAVGTLASGIAHNFNNILG-AILGYAEmALNKLA-----------RHSRAARY 488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 267 INHLnecfkISFTNLeraAKLIsdfkqtaVDQSsLDL---LETNIKDY-LENILHSLMPLTR-SHNVSVNVNCVDDFELI 341
Cdd:PRK13837 489 IDEI-----ISAGAR---ARLI-------IDQI-LAFgrkGERNTKPFdLSELVTEIAPLLRvSLPPGVELDFDQDQEPA 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 342 TV---PGALSQIIMNLVNNSC--------VHGFVGRQDN--QINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFF 408
Cdd:PRK13837 553 VVegnPAELQQVLMNLCSNAAqamdgagrVDISLSRAKLraPKVLSHGVLPPGRYVLLRVSDTGAGIDEAVLPHIFEPFF 632
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1675083294 409 TTKRGSGGSglgmsivyNLAT-----QALQGEVSAASSPSNGMTVNFKLPI 454
Cdd:PRK13837 633 TTRAGGTGL--------GLATvhgivSAHAGYIDVQSTVGRGTRFDVYLPP 675
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
385-453 |
4.74e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 53.92 E-value: 4.74e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1675083294 385 LLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGMSIVYNLATQaLQGEVSAASSPSNGMTVNFKLP 453
Cdd:cd16919 49 CLEVSDTGSGMPAEVLRRAFEPFFTTKEVGKGTGLGLSMVYGFVKQ-SGGHLRIYSEPGVGTTVRIYLP 116
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
183-454 |
3.12e-08 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 56.19 E-value: 3.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 183 LEERVVERTRTLEktlseltemqekliEAEKMASLGNL-----VAGIAHEVNTPIGIAVTANSsakdklsevdkLIQSNT 257
Cdd:PRK15347 373 LENKVAERTQALA--------------EAKQRAEQANKrksehLTTISHEIRTPLNGVLGALE-----------LLQNTP 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 258 LTkaalIESINHLNECFKISFTNLERAAKLIsDFKQTAVDQSSLDLLETNIKDYLENILHSLMplTRSHNVSVNVNCV-- 335
Cdd:PRK15347 428 LT----AEQMDLADTARQCTLSLLAIINNLL-DFSRIESGQMTLSLEETALLPLLDQAMLTIQ--GPAQSKSLTLRTFvg 500
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 336 DDF--ELITVPGALSQIIMNLVNNSCV---HG----FVGRQDNQINISVNideaqgvyllcykDNGHGMDTETLHKVFEP 406
Cdd:PRK15347 501 AHVplYLHLDSLRLRQILVNLLGNAVKfteTGgirlRVKRHEQQLCFTVE-------------DTGCGIDIQQQQQIFTP 567
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1675083294 407 FFTTKRGSGGSGLGMSIVYNLAtQALQGEVSAASSPSNGMTVNFKLPI 454
Cdd:PRK15347 568 FYQADTHSQGTGLGLTIASSLA-KMMGGELTLFSTPGVGSCFSLVLPL 614
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
175-457 |
4.22e-08 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 54.99 E-value: 4.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 175 ELERANQ-----HLEERV-------VERtrtLEKTLSELTEMQEKLIeaekmASLGNLVAGIAHEVNTPIG-----IAVT 237
Cdd:PRK10604 166 KLEAAAQrlgdgHLAERIhfdegssLER---LGVAFNQMADNINALI-----ASKKQLIDGIAHELRTPLVrlryrLEMS 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 238 ANSSAKDKLS---EVDKLiqsntltkAALIESInhlnecfkISFTNLERAaklisdfkqtavdQSSLDLLETNIKDYLEN 314
Cdd:PRK10604 238 DNLSAAESQAlnrDIGQL--------EALIEEL--------LTYARLDRP-------------QNELHLSEPDLPAWLST 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 315 ILHSLMPLTRSHNVSVNVNCVDDFelitvpGALSQIIM-----NLVNNSCVHGfvgrqDNQINISVNIDEAQgvYLLCYK 389
Cdd:PRK10604 289 HLADIQAVTPEKTVRLDTPHQGDY------GALDMRLMervldNLLNNALRYA-----HSRVRVSLLLDGNQ--ACLIVE 355
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1675083294 390 DNGHGMDTETLHKVFEPFF----TTKRGSGGSGLGMSIVYNLAtQALQGEVSAASSPSNGMTVNFKLPIKLA 457
Cdd:PRK10604 356 DDGPGIPPEERERVFEPFVrldpSRDRATGGCGLGLAIVHSIA-LAMGGSVNCDESELGGARFSFSWPVWHN 426
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
23-455 |
4.44e-08 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 55.18 E-value: 4.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 23 VELAERLILNAVLDGLEIGRAGIWLLNKENTAIECRLLLDRENGKEIQMLVLPRDAYPDYFKALDTQRTITAVDAHTDPA 102
Cdd:COG4251 104 LALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLL 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 103 TYEFSESYLTPLNIGAMLDAPIRYKGKMIGIFCCEHIGSERHWTEDECSFIGALADLYGRALSAQENERINAELERANQH 182
Cdd:COG4251 184 LLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEE 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 183 LEERVVERTRTLEKTLSELTE--------MQEKLIeaeKMASLGNLVAgiahevntpigiavtanSSAKDKLSE-VDKLI 253
Cdd:COG4251 264 LEEELEERTAELERSNEELEQfayvashdLREPLR---KISGFSQLLE-----------------EDYGDKLDEeGREYL 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 254 QsnTLTKAAliesinhlnecfkisftnlERAAKLISDFKQTA-VDQSSLDLLETNIKDYLENILHSLMPLTRSHNVSVNV 332
Cdd:COG4251 324 E--RIRDAA-------------------ERMQALIDDLLAYSrVGRQELEFEPVDLNELLEEVLEDLEPRIEERGAEIEV 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 333 NcvddfELITV---PGALSQIIMNLVNNSCVHGfvgRQDNQINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFT 409
Cdd:COG4251 383 G-----PLPTVrgdPTLLRQVFQNLISNAIKYS---RPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQR 454
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1675083294 410 TKRGSGgsglgmsivYN-----LAT-----QALQGEVSAASSPSNGMTVNFKLPIK 455
Cdd:COG4251 455 LHSRDE---------YEgtgigLAIvkkivERHGGRIWVESEPGEGATFYFTLPKA 501
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-452 |
5.31e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 50.53 E-value: 5.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 347 LSQIIMNLVNNS--CVHGFvgrQDNQINISVNIDEAQGVylLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGMSIV 424
Cdd:cd16976 1 IQQVLMNLLQNAldAMGKV---ENPRIRIAARRLGGRLV--LVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGLSIS 75
|
90 100
....*....|....*....|....*...
gi 1675083294 425 YNLAtQALQGEVSAASSPSNGMTVNFKL 452
Cdd:cd16976 76 YGIV-EEHGGRLSVANEEGAGARFTFDL 102
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
176-457 |
8.73e-08 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 54.53 E-value: 8.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 176 LERANQHLEERVVERTRTLEKTLselTEMQEKLIEAEKMA-SLGNLVAGIAHEVNTPI-GIAVTANSSAKDKLSEVDK-L 252
Cdd:PRK11466 405 LNRHREQLAAQVKARTAELQELV---IEHRQARAEAEKASqAKSAFLAAMSHEIRTPLyGILGTAQLLADNPALNAQRdD 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 253 IQSNTLTKAALIESINHLnecfkISFTNLERAAKLIS----DFKQTAVDQSSLDLLETNIKDylenilhslMPLTRSHNV 328
Cdd:PRK11466 482 LRAITDSGESLLTILNDI-----LDYSAIEAGGKNVSvsdePFEPRPLLESTLQLMSGRVKG---------RPIRLATDI 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 329 SVNVNCVddfeLITVPGALSQIIMNLVNNSCvhGFVGRqdNQINISVNIDEAQgvYLLCYKDNGHGMDTETLHKVFEPFF 408
Cdd:PRK11466 548 ADDLPTA----LMGDPRRIRQVITNLLSNAL--RFTDE--GSIVLRSRTDGEQ--WLVEVEDSGCGIDPAKLAEIFQPFV 617
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1675083294 409 TTKRGSGGSGLGMSIVYNLAtQALQGEVSAASSPSNGMTVNFKLPIKLA 457
Cdd:PRK11466 618 QVSGKRGGTGLGLTISSRLA-QAMGGELSATSTPEVGSCFCLRLPLRVA 665
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
300-396 |
9.04e-08 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 54.14 E-value: 9.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 300 SLDLLETNIKDYLENILHSLMPLTRSHNVSVNVNcVDDFEL---ITVPGALsqiIMN-LVNNSCVHGFVGRQDNQINISV 375
Cdd:COG3920 353 SEDWEGVDLRDYLRELLEPLRDSYGGRGIRIELD-GPDVELpadAAVPLGL---ILNeLVTNALKHAFLSGEGGRIRVSW 428
|
90 100
....*....|....*....|.
gi 1675083294 376 NIDEaqGVYLLCYKDNGHGMD 396
Cdd:COG3920 429 RRED--GRLRLTVSDNGVGLP 447
|
|
| GAF |
smart00065 |
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these ... |
30-181 |
1.09e-07 |
|
Domain present in phytochromes and cGMP-specific phosphodiesterases; Mutations within these domains in PDE6B result in autosomal recessive inheritance of retinitis pigmentosa.
Pssm-ID: 214500 [Multi-domain] Cd Length: 149 Bit Score: 50.84 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 30 ILNAVLD----GLEIGRAGIWLLN-KENTAIECRLLLDrengkeiQMLVLPRDAYPDYF----KALDTQRTITAVDAHTD 100
Cdd:smart00065 5 LLQTILEelrqLLGADRVLIYLVDeNDRGELVLVAADG-------LTLPTLGIRFPLDEglagRVAETGRPLNIPDVEAD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 101 P-ATYEFSESYLtplNIGAMLDAPIRYKGKMIGIFCCEHIGSERHWTEDECSFIGALADLYGRALSaqeneriNAELERA 179
Cdd:smart00065 78 PlFAEDLLGRYQ---GVRSFLAVPLVADGELVGVLALHNKKSPRPFTEEDEELLQALANQLAIALA-------NAQLYEE 147
|
..
gi 1675083294 180 NQ 181
Cdd:smart00065 148 LR 149
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
282-411 |
9.28e-06 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 47.54 E-value: 9.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 282 ERAAKLISdfKQTAVDQSSLDLLETNIKD-YLENILHSLMPLTRSHNVSVNVNCVDDFELITV-PGALSQIIMNLVNNSc 359
Cdd:COG3290 217 DEALEYID--EISEELQELIDSLLSRIGNpVLAALLLGKAARARERGIDLTIDIDSDLPDLPLsDTDLVTILGNLLDNA- 293
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1675083294 360 VHGFVGRQDNQINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTK 411
Cdd:COG3290 294 IEAVEKLPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTK 345
|
|
| PtsP |
COG3605 |
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms]; |
96-189 |
1.28e-05 |
|
Signal transduction protein containing GAF and PtsI domains [Signal transduction mechanisms];
Pssm-ID: 442824 [Multi-domain] Cd Length: 188 Bit Score: 45.66 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 96 DAHTDPATYEFSESYLTPLNigAMLDAPIRYKGKMIGIFCCEHIgSERHWTEDECSFIGALADLYGRALsaqENERINAE 175
Cdd:COG3605 90 DAASHPRFKYFPETGEEGFR--SFLGVPIIRRGRVLGVLVVQSR-EPREFTEEEVEFLVTLAAQLAEAI---ANAELLGE 163
|
90
....*....|....
gi 1675083294 176 LERANQHLEERVVE 189
Cdd:COG3605 164 LRAALAELSLAREE 177
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-453 |
1.67e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 43.54 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 347 LSQIIMNLVNN---SCVHGfvGRQDNQINISVNIDEAQGVyLLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGS--GLGM 421
Cdd:cd16920 1 IQQVLINLVRNgieAMSEG--GCERRELTIRTSPADDRAV-TISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMglSICR 77
|
90 100 110
....*....|....*....|....*....|..
gi 1675083294 422 SIVynlatQALQGEVSAASSPSNGMTVNFKLP 453
Cdd:cd16920 78 SII-----EAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-453 |
4.16e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 42.41 E-value: 4.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 343 VPGALSQIimnLVNNSCVHGFVGRQDNQiNISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSglgms 422
Cdd:cd16957 1 VPPFALQV---LVENAIRHAFPKRKENN-EVRVVVKKDQHKVHVSVSDNGQGIPEERLDLLGKTTVTSEKGTGTA----- 71
|
90 100 110
....*....|....*....|....*....|....*.
gi 1675083294 423 iVYNLATQ--ALQGEVSA---ASSPSNGMTVNFKLP 453
Cdd:cd16957 72 -LENLNRRliGLFGSEAClhiESEVHGGTEVWFVIP 106
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
149-456 |
4.92e-05 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 45.88 E-value: 4.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 149 ECSFIGALADLYGRALSAQENERINAELERANQHLEERVVERTRTL------EKTL-----SELTEMQEKL--IEAEKMA 215
Cdd:PRK09959 625 DSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLcnlpasDHAVyicgwQDITETRDLIhaLEVERNK 704
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 216 SL------GNLVAGIAHEVNTPIgiavtanSSAKDKLsevdKLIQSNTLTKAALIESINhlnecfkISFTNLERAAKLIS 289
Cdd:PRK09959 705 AInatvakSQFLATMSHEIRTPI-------SSIMGFL----ELLSGSGLSKEQRVEAIS-------LAYATGQSLLGLIG 766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 290 ---DFKQTAVDQSSLDLLETNIKDYLENILHSLMPLTRSHNVSVNVNCV-DDFELITV-PGALSQIIMNLVNNSCvhGFV 364
Cdd:PRK09959 767 eilDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTfPDHYLVKIdPQAFKQVLSNLLSNAL--KFT 844
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 365 GRQDNQINIS-VNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTK--RGSGGSGLGMSIVYNLaTQALQGEVSAASS 441
Cdd:PRK09959 845 TEGAVKITTSlGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSagRQQTGSGLGLMICKEL-IKNMQGDLSLESH 923
|
330
....*....|....*
gi 1675083294 442 PSNGMTVNFKLPIKL 456
Cdd:PRK09959 924 PGIGTTFTITIPVEI 938
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-409 |
1.23e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 41.12 E-value: 1.23e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1675083294 346 ALSQIIMNLVNNSCVHGfvgrqdnqiNISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFFT 409
Cdd:cd16948 9 IIGQIVSNALKYSKQGG---------KIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFT 63
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-451 |
1.37e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 40.91 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 346 ALSQIIMNLVNNSCVHGfvgRQDNQINISVNIDEAQGVYLLCykDNGHGMDTETLHKVFEPFF---TTKRGSGGSGLGMS 422
Cdd:cd16975 4 LLSRALINIISNACQYA---PEGGTVSISIYDEEEYLYFEIW--DNGHGFSEQDLKKALELFYrddTSRRSGGHYGMGLY 78
|
90 100
....*....|....*....|....*....
gi 1675083294 423 IVYNLATQaLQGEVSAASSPSNGMTVNFK 451
Cdd:cd16975 79 IAKNLVEK-HGGSLIIENSQKGGAEVTVK 106
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
256-412 |
1.92e-04 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 43.47 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 256 NTLtkaaliESINHLnecfkISFTNLERAAKLISD----FKQTAVDQSSLDLLE---TNIKDYLEnilhsLMPLTRSHNV 328
Cdd:COG2972 258 NTL------NSIRWL-----AELEDPEEAEEMLEAlsklLRYSLSKGDELVTLEeelELIKSYLE-----IQKLRFGDRL 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 329 SVNVNCVDDFELITVPgalSQIIMNLVNNSCVHGFvGRQDNQINISVNIDEAQGVYLLCYKDNGHGMDTETLHKVFEPFF 408
Cdd:COG2972 322 EVEIEIDEELLDLLIP---KLILQPLVENAIEHGI-EPKEGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELS 397
|
....
gi 1675083294 409 TTKR 412
Cdd:COG2972 398 SKGE 401
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-411 |
3.64e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 39.83 E-value: 3.64e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1675083294 346 ALSQIIMNLVNNScVHGFVGRQDNQINISVNI-DEAQGVYLLCYKDNGHGMDTETLHKVFEPFFTTK 411
Cdd:cd16944 4 QISQVLTNILKNA-AEAIEGRPSDVGEVRIRVeADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTR 69
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-453 |
6.19e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 39.23 E-value: 6.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 347 LSQIIMNLVNNSCVHGfvgRQDNQINISVNIDEAQgvylLCYKDNGHGMDTETLHKVFEPFFTTKRGSGGSGLGMSIVYN 426
Cdd:cd16949 1 LARALENVLRNALRYS---PSKILLDISQDGDQWT----ITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLA 73
|
90 100 110
....*....|....*....|....*....|
gi 1675083294 427 LATQALQ---GEVSAASSPSNGMTVNFKLP 453
Cdd:cd16949 74 IAERAIEqhgGKIKASNRKPGGLRVRIWLP 103
|
|
| GAF_2 |
pfam13185 |
GAF domain; The GAF domain is named after some of the proteins it is found in, including ... |
84-164 |
9.82e-04 |
|
GAF domain; The GAF domain is named after some of the proteins it is found in, including cGMP-specific phosphodiesterases, adenylyl cyclases and FhlA. It is also found in guanylyl cyclases and phytochromes. The structure of a GAF domain shows that the domain shares a similar fold with the PAS domain. This domain can bind O2, CO and NO (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 433019 [Multi-domain] Cd Length: 137 Bit Score: 39.37 E-value: 9.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 84 KALDTQRTITAVDAHTDPAtyeFSESYLTPLNIGAMLDAPIRYKGKMIGIFCCEHiGSERHWTEDECSFIGALADLYGRA 163
Cdd:pfam13185 60 EALRTGRPVIVNDLAADPA---KKGLPAGHAGLRSFLSVPLVSGGRVVGVLALGS-NRPGAFDEEDLELLELLAEQAAIA 135
|
.
gi 1675083294 164 L 164
Cdd:pfam13185 136 I 136
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
390-454 |
1.32e-03 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 41.19 E-value: 1.32e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1675083294 390 DNGHGMDTETLHKVFEPFFTTKRGSGGSGLGMSIVYNLATQAlQGEVSAASSPSNGMTVNFKLPI 454
Cdd:PRK13557 331 DTGSGMPPEILARVMDPFFTTKEEGKGTGLGLSMVYGFAKQS-GGAVRIYSEVGEGTTVRLYFPA 394
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
347-453 |
2.50e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 37.47 E-value: 2.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 347 LSQIIMNLVNNScV----HGFVGrqdnqINISVNIDEAQGVYL-LCYKDNGHGMDTETLHKVFEPFF----TTKRGSGGS 417
Cdd:cd16922 1 LRQILLNLLGNA-IkfteEGEVT-----LRVSLEEEEEDGVQLrFSVEDTGIGIPEEQQARLFEPFSqadsSTTRKYGGT 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 1675083294 418 GLGMSIVYNLAtQALQGEVSAASSPSNGMTVNFKLP 453
Cdd:cd16922 75 GLGLAISKKLV-ELMGGDISVESEPGQGSTFTFTLP 109
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
286-454 |
3.63e-03 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 39.62 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 286 KLISDFKQTAV-DQSSLDLLET--NIKDYLENILHSLMPLTRSHNVSVNVNCVDDFELITVPGALSQIIMNLVNNSCVHG 362
Cdd:PRK10549 289 KLVDDLHQLSLsDEGALAYRKTpvDLVPLLEVAGGAFRERFASRGLTLQLSLPDSATVFGDPDRLMQLFNNLLENSLRYT 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 363 FVGrqdNQINISVNIDEAQgvYLLCYKDNGHGMDTETLHKVFEPFFTTK----RGSGGSGLGMSIVYNLaTQALQGEVSA 438
Cdd:PRK10549 369 DSG---GSLHISAEQRDKT--LRLTFADSAPGVSDEQLQKLFERFYRTEgsrnRASGGSGLGLAICLNI-VEAHNGRIIA 442
|
170
....*....|....*.
gi 1675083294 439 ASSPSNGMTVNFKLPI 454
Cdd:PRK10549 443 AHSPFGGVSITVELPL 458
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-453 |
9.05e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 35.90 E-value: 9.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675083294 344 PGALSQIIMNLVNNSCVHGFVGrqdNQINISVNiDEAQGVYLLcYKDNGHGMDTETLHKVFEPFFTT----KRGSGGSGL 419
Cdd:cd16946 2 RDRLQQLFVNLLENSLRYTDTG---GKLRIRAA-QTPQEVRLD-VEDSAPGVSDDQLARLFERFYRVessrNRASGGSGL 76
|
90 100 110
....*....|....*....|....*....|....
gi 1675083294 420 GMSIVYNLAtQALQGEVSAASSPSNGMTVNFKLP 453
Cdd:cd16946 77 GLAICHNIA-LAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| |
