|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-787 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1651.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 1 MQEYVLWYQELGMQDVPRVGGKNASLGEMISNLANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 81 KVGAEIRQWIIDTPFQPNLDQAIRDAYSQLhGDASQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVF 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKL-SAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 161 ASLFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDKAASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVH 240
Cdd:PRK06464 162 ASLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 241 KPTLANGKPAVVRRNIGSKAIQMIYSADESHGkqVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKD 320
Cdd:PRK06464 242 KPTLKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKD 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 321 GNDGKLYIVQARPETVRSNEDANVMERFQLNGTSTVVAEGRAIGHKIGSGTVRVLDSIDEMDKVQQGDILVTDMTDPDWE 400
Cdd:PRK06464 320 GDDGKLYIVQARPETVKSRKEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWE 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 401 PIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVSCAEGDTGYIYEGILDYEVLTSRVDEMPEL 480
Cdd:PRK06464 400 PVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPET 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 481 PMKVMMNVGNPDRAFDFARLPHAGVGLARVEFVINRMIGVHPKALLNFDAQSDELKAEISEMMAGYESPVEFYISKLVEG 560
Cdd:PRK06464 480 PTKIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 561 IATLGCAFAPERVIVRMSDFKSNEYANLVGGQQYEPEEENPMIGFRGAARYISEDFRDCFALECEAIKRVRNEMGMTNIE 640
Cdd:PRK06464 560 IATVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 641 IMIPFVRTLEEGKRVIELLEEHGLKRGENGLKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHL 720
Cdd:PRK06464 640 VMIPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHL 719
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1675102822 721 FDERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDHEDFAAWLVEQGIDSVSLNPDTVLETWLYLAK 787
Cdd:PRK06464 720 FDERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAE 786
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-787 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1327.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 4 YVLWYQELGMQDVPRVGGKNASLGEMISNLANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLAKVG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 84 AEIRQWIIDTPFQPNLDQAIRDAYSQL-HGDASQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVFAS 162
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLsEDYGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 163 LFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDKAASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVHKP 242
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 243 TLANGKPAVVRRNIGSKAIQMIYSADEShGKQVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKDGN 322
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVYDPDGG-GVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 323 DGKLYIVQARPETVRSNE-DANVMERFQLNGTSTVVAEGRAIGHKIGSGTVRVLDSIDEMDKVQQGDILVTDMTDPDWEP 401
Cdd:TIGR01418 320 DGEIFIVQARPETVQSRKkKENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 402 IMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVSCAEGDTGYIYEGILDYEVLTSRVDEMPELP 481
Cdd:TIGR01418 400 AMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 482 MKVMMNVGNPDRAFDFARLPHAGVGLARVEFVINRMIGVHPKALLNFDAQSDELKAEISEMMAGyeSPVEFYISKLVEGI 561
Cdd:TIGR01418 480 TKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 562 ATLGCAFAPERVIVRMSDFKSNEYANLVGGQQYEPEEENPMIGFRGAARYISEDFRDCFALECEAIKRVRNEMGMTNIEI 641
Cdd:TIGR01418 558 AKVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 642 MIPFVRTLEEGKRVIELLEEHGLKRGENGLKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHLF 721
Cdd:TIGR01418 638 MIPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLF 717
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1675102822 722 DERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDHEDFAAWLVEQGIDSVSLNPDTVLETWLYLAK 787
Cdd:TIGR01418 718 DERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-460 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 676.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 1 MQEYVLWYQELGMQDVPRVGGKNASLGEMIsnlaNAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMT----RLGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 81 KVGAEIRQWIIDTPFQPNLDQAIRDAYSQLHGDASQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVF 160
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKFGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 161 ASLFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDKAASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVH 240
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 241 KPTlangkpaVVRRNIGSKAIQMIYSADeshgkqVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKD 320
Cdd:COG0574 237 KPT-------ILERTLGSKAIKMVYDGG------TVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAID 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 321 gnDGKLYIVQARPETVRSN--------------EDANVMERFQLN--GTSTVVAEGRAIGHKIGSGTVRVLDSIDEMDKV 384
Cdd:COG0574 304 --DGKLYILQTRPITVLEGlitkeallrvdpaqLDQLLHPRFDPKakEEGEVLAKGLPASPGAASGKVVFIADEAELARF 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1675102822 385 QQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVscaEGDTGYI 460
Cdd:COG0574 382 QEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
16-351 |
2.29e-162 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 473.23 E-value: 2.29e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 16 VPRVGGKNASLGEMisnLANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLAKVGAEIRQWIIDTPF 95
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 96 QPNLDQAIRDAYSQL---HGDAsqDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVFASLFNDRAISYR 172
Cdd:pfam01326 78 PEELEEAIREAYEELgkkFGDE--PLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 173 VHQGYDHRGVALSAGIQRMVRSDkaASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVHKPTLangkpAVV 252
Cdd:pfam01326 156 REKGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTL-----EIL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 253 RRNIGSKAIQMIYSADESHgkqVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKDGNDGKLYIVQAR 332
Cdd:pfam01326 229 RRTIGEKEIKMVYDEGGEG---TKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQAR 305
|
330 340
....*....|....*....|
gi 1675102822 333 PETVRSNE-DANVMERFQLN 351
Cdd:pfam01326 306 PETVWSEAmEKIAAEILEEG 325
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06464 |
PRK06464 |
phosphoenolpyruvate synthase; Validated |
1-787 |
0e+00 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235809 [Multi-domain] Cd Length: 795 Bit Score: 1651.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 1 MQEYVLWYQELGMQDVPRVGGKNASLGEMISNLANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLA 80
Cdd:PRK06464 3 MMKYVLWFEELGMEDVPLVGGKNASLGEMISNLSGAGVPVPPGFATTAEAYRYFLEQTGLNEKIYELLDGLDVDDVDALA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 81 KVGAEIRQWIIDTPFQPNLDQAIRDAYSQLhGDASQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVF 160
Cdd:PRK06464 83 KAGAQIRQLIIDTPFPPDLEQEIREAYAKL-SAGYGEASVAVRSSATAEDLPDASFAGQQETFLNVRGIDDVLEAVKECF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 161 ASLFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDKAASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVH 240
Cdd:PRK06464 162 ASLFTDRAISYRVHQGFDHFKVALSAGVQKMVRSDLAASGVMFTLDTESGFRDVVFITASWGLGEMVVQGAVNPDEFYVH 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 241 KPTLANGKPAVVRRNIGSKAIQMIYSADESHGkqVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKD 320
Cdd:PRK06464 242 KPTLKAGKPAIVRRTLGSKKIKMVYDDGGEHG--VKTVDVPEEERNRFSLTDEEVLELAKQAVIIEKHYGRPMDIEWAKD 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 321 GNDGKLYIVQARPETVRSNEDANVMERFQLNGTSTVVAEGRAIGHKIGSGTVRVLDSIDEMDKVQQGDILVTDMTDPDWE 400
Cdd:PRK06464 320 GDDGKLYIVQARPETVKSRKEANVLERYKLKGQGKVLVEGRAIGPGIGSGKVRVILDISEMDKVQPGDVLVTDMTDPDWE 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 401 PIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVSCAEGDTGYIYEGILDYEVLTSRVDEMPEL 480
Cdd:PRK06464 400 PVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGTGNATEVLKDGQEVTVSCAEGDTGYVYEGLLEFEVEEVSLEEMPET 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 481 PMKVMMNVGNPDRAFDFARLPHAGVGLARVEFVINRMIGVHPKALLNFDAQSDELKAEISEMMAGYESPVEFYISKLVEG 560
Cdd:PRK06464 480 PTKIMMNVGNPERAFDFAALPNDGVGLARLEFIINNMIGVHPLALLEFDQQDADLKAEIEELTAGYASPEEFYVDKLAEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 561 IATLGCAFAPERVIVRMSDFKSNEYANLVGGQQYEPEEENPMIGFRGAARYISEDFRDCFALECEAIKRVRNEMGMTNIE 640
Cdd:PRK06464 560 IATVAAAFYPKPVIVRLSDFKSNEYANLIGGERYEPEEENPMLGFRGASRYLSESFREAFALECEAIKRVREEMGLTNVE 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 641 IMIPFVRTLEEGKRVIELLEEHGLKRGENGLKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHL 720
Cdd:PRK06464 640 VMIPFVRTVEEAEKVIELLAENGLKRGENGLKVIMMCEIPSNALLAEEFLEYFDGFSIGSNDLTQLTLGLDRDSGLVAHL 719
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1675102822 721 FDERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDHEDFAAWLVEQGIDSVSLNPDTVLETWLYLAK 787
Cdd:PRK06464 720 FDERNPAVKKLISMAIKAAKKAGKYVGICGQAPSDHPDFAEWLVEEGIDSISLNPDAVVDTWLAVAE 786
|
|
| PEP_synth |
TIGR01418 |
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member ... |
4-787 |
0e+00 |
|
phosphoenolpyruvate synthase; Also called pyruvate,water dikinase and PEP synthase. The member from Methanococcus jannaschii contains a large intein. This enzyme generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process. The enzyme shows extensive homology to other enzymes that use PEP as substrate or product. This enzyme may provide PEP for gluconeogenesis, for PTS-type carbohydrate transport systems, or for other processes. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273612 [Multi-domain] Cd Length: 786 Bit Score: 1327.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 4 YVLWYQELGMQDVPRVGGKNASLGEMISNLANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLAKVG 83
Cdd:TIGR01418 1 LILWLEEVRKDDVPLVGGKNASLGEMIQNLSPAGVPVPPGFVVTAEAYRYFLEENGIAQKIRDLLEELDVEDVDALAAAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 84 AEIRQWIIDTPFQPNLDQAIRDAYSQL-HGDASQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVFAS 162
Cdd:TIGR01418 81 AEIRELILNTPFPPDLEEAIREAYDKLsEDYGKEEADVAVRSSATAEDLPDASFAGQQETYLNVTGEEEVLEHVKKCWAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 163 LFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDKAASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVHKP 242
Cdd:TIGR01418 161 LFTDRAISYRVSQGFDHEKVAIAVGVQKMVRSDLGSSGVMFTIDTETGFKDAVFIESAWGLGEAVVGGAVTPDEYVVFKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 243 TLANGKPAVVRRNIGSKAIQMIYSADEShGKQVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKDGN 322
Cdd:TIGR01418 241 TLEQGKKAILERTLGSKKIKMVYDPDGG-GVETKIVEVPEEERDAFSLSDEEILELAKLAVLIEKHYGRPMDIEWAKDGF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 323 DGKLYIVQARPETVRSNE-DANVMERFQLNGTSTVVAEGRAIGHKIGSGTVRVLDSIDEMDKVQQGDILVTDMTDPDWEP 401
Cdd:TIGR01418 320 DGEIFIVQARPETVQSRKkKENVEERYELKGKGKVLVTGRAAGPGIASGKVKVIFDLKEMDKFEEGDILVTDMTDPDWEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 402 IMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVSCAEGDTGYIYEGILDYEVLTSRVDEMPELP 481
Cdd:TIGR01418 400 AMKRASAIVTNEGGMTCHAAIVARELGIPAVVGTGDATKTLKDGMEVTVDCAEGDTGYVYAGKLEHEVKEVELSNMPVTA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 482 MKVMMNVGNPDRAFDFARLPHAGVGLARVEFVINRMIGVHPKALLNFDAQSDELKAEISEMMAGyeSPVEFYISKLVEGI 561
Cdd:TIGR01418 480 TKIYMNVGNPEVAFRFAALPNDGVGLARIEFIILNWIGKHPLALIDDDDLESVEKNEIEELMAG--NPRDFFVDKLAEGI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 562 ATLGCAFAPERVIVRMSDFKSNEYANLVGGQQYEPEEENPMIGFRGAARYISEDFRDCFALECEAIKRVRNEMGMTNIEI 641
Cdd:TIGR01418 558 AKVAAAFYPKPVIVRTSDFKSNEYRNLIGGEEYEPDEENPMLGWRGASRYYSESYEEAFRLECRAIKRVREEMGLTNVEV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 642 MIPFVRTLEEGKRVIELLEEHGLKRGENGLKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHLF 721
Cdd:TIGR01418 638 MIPFVRTPEEGKRALEIMAEEGLRRGKNGLEVYVMCEVPSNALLADEFAKEFDGFSIGSNDLTQLTLGVDRDSGLVAHLF 717
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1675102822 722 DERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDHEDFAAWLVEQGIDSVSLNPDTVLETWLYLAK 787
Cdd:TIGR01418 718 DERNPAVLRLIEMAIKAAKEHGKKVGICGQAPSDYPEVVEFLVEEGIDSISLNPDAVLRTRLQVAE 783
|
|
| PpsA |
COG0574 |
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and ... |
1-460 |
0e+00 |
|
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase [Carbohydrate transport and metabolism]; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase is part of the Pathway/BioSystem: Gluconeogenesis
Pssm-ID: 440339 [Multi-domain] Cd Length: 455 Bit Score: 676.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 1 MQEYVLWYQELGMQDVPRVGGKNASLGEMIsnlaNAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLA 80
Cdd:COG0574 1 MTKYVYWFAEGGADDVDLVGGKGANLGEMT----RLGLPVPPGFTITTEAYRRFLEENGLEEEIRELLADLDVDDVDALA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 81 KVGAEIRQWIIDTPFQPNLDQAIRDAYSQLHGDASQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVF 160
Cdd:COG0574 77 EASAEIRELILEAPLPEELEEEILAAYAKLEEKFGEDLLVAVRSSATAEDLPDASFAGQMDTVLNVNGNEQLLEAIKAVF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 161 ASLFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDKAASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVH 240
Cdd:COG0574 157 ASLFTDRAIAYRRHNGIDHDDVGTAVNVQAMVFGNMSASGVMFTRDPSTGEKDVVYIEALNGLGEDVVAGIVTPDPYYVD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 241 KPTlangkpaVVRRNIGSKAIQMIYSADeshgkqVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKD 320
Cdd:COG0574 237 KPT-------ILERTLGSKAIKMVYDGG------TVEVPVPPEERNRPSLTDEEYLELARIALRLEKHYGDPQDIEWAID 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 321 gnDGKLYIVQARPETVRSN--------------EDANVMERFQLN--GTSTVVAEGRAIGHKIGSGTVRVLDSIDEMDKV 384
Cdd:COG0574 304 --DGKLYILQTRPITVLEGlitkeallrvdpaqLDQLLHPRFDPKakEEGEVLAKGLPASPGAASGKVVFIADEAELARF 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1675102822 385 QQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVscaEGDTGYI 460
Cdd:COG0574 382 QEGVILVRDETDPDDVPGMKAAAGIVTERGGMTSHAAIVARELGIPAVVGCGDATRVLKDGDEITV---DGTTGEV 454
|
|
| PPDK_N |
pfam01326 |
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible ... |
16-351 |
2.29e-162 |
|
Pyruvate phosphate dikinase, AMP/ATP-binding domain; This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP). The N-terminal domain has been shown to be the AMP/ATP-binding domain.
Pssm-ID: 426201 [Multi-domain] Cd Length: 326 Bit Score: 473.23 E-value: 2.29e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 16 VPRVGGKNASLGEMisnLANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLAKVGAEIRQWIIDTPF 95
Cdd:pfam01326 1 VNLVGGKGANLGEM---LNDAGIPVPPGFAITADAYREFLEENGLREKIDELLKDLDVDDVDELREASKEIRQLILSAPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 96 QPNLDQAIRDAYSQL---HGDAsqDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVFASLFNDRAISYR 172
Cdd:pfam01326 78 PEELEEAIREAYEELgkkFGDE--PLPVAVRSSATAEDLPDASFAGQQDTYLNVGGNDEVLEAIKAVFASLFNDRAIAYR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 173 VHQGYDHRGVALSAGIQRMVRSDkaASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVHKPTLangkpAVV 252
Cdd:pfam01326 156 REKGIDHEDVALAVGVQRMVRSD--ASGVMFSRDPETGFRDEVLINASWGLGEAVVQGRVTPDEFYVFKPTL-----EIL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 253 RRNIGSKAIQMIYSADESHgkqVEIVDVDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKDGNDGKLYIVQAR 332
Cdd:pfam01326 229 RRTIGEKEIKMVYDEGGEG---TKEVEVPEEKRERFSLSDEEVLELARIAKKIEKHYGTPMDIEWAIDGRDGKLYILQAR 305
|
330 340
....*....|....*....|
gi 1675102822 333 PETVRSNE-DANVMERFQLN 351
Cdd:pfam01326 306 PETVWSEAmEKIAAEILEEG 325
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
1-335 |
2.48e-102 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 335.32 E-value: 2.48e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 1 MQEYVLWYQELGMQDVPRVGGKNASLGEMisnlANAGVQVPGGFATTADAFNEFLEQSGLNSKIHDILDTLDVDDVNTLA 80
Cdd:PRK06241 1 MSSYVLDFQEIDKTQLPLVGGKGANLGEL----SRAGIPVPEGFCVTTEAYKKFLEQNEEFDALLDQLSALKLEDREQIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 81 KVGAEIRQWIIDTPFQPNLDQAIRDAYSQLhgdaSQDVSFAVRSSATAEDMPDASFAGQQETFLNVRGIDAVMTAIKHVF 160
Cdd:PRK06241 77 EISAKIREVIEAIEIPEDIVEAIAAALSKF----GEDHAYAVRSSATAEDLPTASFAGQQDTYLNVIGKDAILQHIRKCW 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 161 ASLFNDRAISYRVHQGYDHRGVALSAGIQRMVRSDkaASGVMFSIDTESGFEDVVFVTSSYGLGEMVVQGAVNPDEFYVH 240
Cdd:PRK06241 153 ASLFTERAVIYRIQNGFDHRKVYMSVVVQKMVFPE--ASGIMFTADPVTGNRKVLSIDASFGLGEALVSGLVSADTYKVR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 241 KPTlangkpaVVRRNIGSKAIqMIYSADESHGKQVEIvdvDSSLSNKFSITDAEVQELAKQAVIIEKHYGRPMDIEWAKD 320
Cdd:PRK06241 231 EGK-------IIDKTIATKKL-AIYALKEGGTETKEI---EPEQQKSQTLTDEQILELARLGRKIEAHFGCPQDIEWCLA 299
|
330
....*....|....*
gi 1675102822 321 gnDGKLYIVQARPET 335
Cdd:PRK06241 300 --DGTFYILQSRPIT 312
|
|
| PEP-utilizers_C |
pfam02896 |
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at ... |
483-787 |
2.85e-64 |
|
PEP-utilizing enzyme, PEP-binding domain; This entry represents a TIM barrel domain found at the C terminus of a number of PEP (phosphoenolpyruvate)-utilizing proteins. In PPDK (Pyruvate phosphate dikinase) this C-terminal domain has been shown to be a PEP-binding domain.
Pssm-ID: 397163 [Multi-domain] Cd Length: 292 Bit Score: 216.40 E-value: 2.85e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 483 KVMMNVGNPDRAFDFARLPHAGVGLARVEFVINrmigvhpkallnfdaQSDELKAEIsemmagyespvefyisKLVEGIA 562
Cdd:pfam02896 21 KVAANIGTPDDAEAALANGAEGIGLYRTEFLFM---------------DRDELPTED----------------EQFEAYK 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 563 TLGCAFAPERVIVRMSDFKSNEYanLVGGqqYEPEEENPMIGFRGAARYISEdfRDCFALECEAIKRVRNEMgmtNIEIM 642
Cdd:pfam02896 70 GVLEAMNGRPVTVRTLDIGGDKE--LPYL--EEPEEMNPFLGWRGIRIGLDR--PELFRTQLRAILRASAFG---NLRIM 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 643 IPFVRTLEEGKRVIELLEEHGLKRGEN-----GLKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLI 717
Cdd:pfam02896 141 FPMVASVEELREAKAIIEEVKEELDAEvgfdkDIKVGIMIEVPSAALLADQLAKEVDFFSIGTNDLTQYTLAVDRDNERV 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 718 AHLFDERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDhEDFAAWLVEQGIDSVSLNPDTVLETWLYLAK 787
Cdd:pfam02896 221 AYLYDPLHPAVLRLIKEVIRAAHRHGKWVGICGEMAGD-PSAVPLLVGLGLDEFSMSPDSVPRARALLAQ 289
|
|
| PtsA |
COG1080 |
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate ... |
404-781 |
4.47e-50 |
|
Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism];
Pssm-ID: 440698 [Multi-domain] Cd Length: 571 Bit Score: 185.28 E-value: 4.47e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 404 KRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVscaEGDTGYIY----EGILD--------YEVLT 471
Cdd:COG1080 173 SRVAGFVTDLGGRTSHTAILARSLGIPAVVGLGDALLLVKDGDLVIV---DGDAGVVIvnpdEETLAeyrerqaeYAAER 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 472 SRVDEMPELP--------MKVMMNVGNPDRAfDFARLPHA-GVGLARVEFV-INRmigvhpKALLNFDAQsdelkaeise 541
Cdd:COG1080 250 AELARLRDLPavtldgvrVELAANIGLPEDA-AAALENGAeGVGLFRTEFLfMDR------DDLPTEEEQ---------- 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 542 mmagyespVEFYiSKLVEgiatlgcAFAPERVIVRMSDF---KSNEYANLvggqqyePEEENPMIGFRgAARYiSEDFRD 618
Cdd:COG1080 313 --------FEAY-RAVAE-------AMGGRPVTIRTLDIggdKPLPYLPL-------PKEENPFLGLR-AIRL-CLDRPE 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 619 CFALECEAIKRVRNEmgmTNIEIMIPFVRTLEEGKRVIELLEEH-------GLKRGENgLKVIMMCELPSNALLADEFLE 691
Cdd:COG1080 368 LFRTQLRAILRASAH---GNLRIMFPMISSVEELRQAKALLEEAkaelraeGIPFDED-IPVGIMIEVPAAALIADQLAK 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 692 YFDGFSIGSNDLTQLTLGLDRDSGLIAHLFDERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDhEDFAAWLVEQGIDSV 771
Cdd:COG1080 444 EVDFFSIGTNDLIQYTLAVDRGNEKVAYLYDPLHPAVLRLIKMVIDAAHKAGKPVGVCGEMAGD-PLATPLLLGLGLDEL 522
|
410
....*....|
gi 1675102822 772 SLNPDTVLET 781
Cdd:COG1080 523 SMSPSSIPAV 532
|
|
| PTS_I_fam |
TIGR01417 |
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of ... |
361-787 |
1.01e-42 |
|
phosphoenolpyruvate-protein phosphotransferase; This model recognizes a distinct clade of phophoenolpyruvate (PEP)-dependent enzymes. Most members are known or deduced to function as the phosphoenolpyruvate-protein phosphotransferase (or enzyme I) of PTS sugar transport systems. However, some species with both a member of this family and a homolog of the phosphocarrier protein HPr lack a IIC component able to serve as a permease. An HPr homolog designated NPr has been implicated in the regulation of nitrogen assimilation, which demonstrates that not all phosphotransferase system components are associated directly with PTS transport.
Pssm-ID: 273611 [Multi-domain] Cd Length: 565 Bit Score: 163.81 E-value: 1.01e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 361 RAIGHKIGSgtvrvldSIDEMDKVQQGDILVT-DMTDPDWEPI-MKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNA 438
Cdd:TIGR01417 135 RLLGHLLGV-------KISDLSEIQDEVILVAeDLTPSETAQLnLKYVKGFLTDAGGKTSHTAIMARSLEIPAIVGTKSV 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 439 TDLIKAGQDVTVSCAEGDTGY--IYEGILDYEVLTSRV-DEMPELPMK--------------VMMNVGNPDRAFDFARLP 501
Cdd:TIGR01417 208 TSQVKNGDTVIIDGVKGIVIFnpSSETIDKYEAKQEAVsSEKAELAKLkdkpaitldghqveLAANIGTVDDVEGAERNG 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 502 HAGVGLARVEFVINRmigvhpkallnfdaqSDELKAEiSEMMAGYESPVEFYISKLVegiatlgcafapervIVRMSDF- 580
Cdd:TIGR01417 288 GEGIGLFRTEFLYMS---------------RDQLPTE-EEQFAAYKTVLEAMESDAV---------------IVRTLDIg 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 581 --KSNEYANLvggqqyePEEENPMIGFRgAARyISEDFRDCFALECEAIKRVRNEmgmTNIEIMIPFVRTLEEGKRVIEL 658
Cdd:TIGR01417 337 gdKELPYLNF-------PKEENPFLGYR-AIR-LALEREEILRTQLRAILRASAY---GKLRIMFPMVATVEEIRAVKQE 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 659 LEEHGLKRGENG------LKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHLFDERNPAIKKLL 732
Cdd:TIGR01417 405 LEEEKQELNDEGkafdenIEVGVMIEIPSAALIADHLAKEVDFFSIGTNDLTQYTLAVDRGNDLISNLYQPYNPAVLRLI 484
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1675102822 733 SMAIQTAKAKGKYVGICGQGPSDHEdFAAWLVEQGIDSVSLNPDTVLETWLYLAK 787
Cdd:TIGR01417 485 KLVIDAAKAEGIWVGMCGEMAGDER-AIPLLLGLGLRELSMSASSILRIKMIIRK 538
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
354-464 |
1.17e-34 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 134.64 E-value: 1.17e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 354 STVVAEGRAIGHKIGSGTVRVLDSIDE-MDKVQQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAV 432
Cdd:COG3848 209 GDVLAKGQGIGRGSVTGKAVVARSAEEaLEKFEEGDILVVPSTDAEFVPAIEKAAGIITEEGGLTSHAAIVGLELGIPVI 288
|
90 100 110
....*....|....*....|....*....|..
gi 1675102822 433 VGCGNATDLIKAGQDVTVscaEGDTGYIYEGI 464
Cdd:COG3848 289 VGAEGATEILKDGQVVTV---DAERGVVYRGA 317
|
|
| PEP-utilizers |
pfam00391 |
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain ... |
383-455 |
8.48e-33 |
|
PEP-utilizing enzyme, mobile domain; This domain is a "swivelling" beta/beta/alpha domain which is thought to be mobile in all proteins known to contain it.
Pssm-ID: 459796 [Multi-domain] Cd Length: 73 Bit Score: 120.98 E-value: 8.48e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1675102822 383 KVQQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVSCAEG 455
Cdd:pfam00391 1 KLPEGVILVAPDTTPSDTAGLDKAAGIVTERGGMTSHAAIVARELGIPAVVGVGDATILLKEGDLVTVDGSTG 73
|
|
| PRK11177 |
PRK11177 |
phosphoenolpyruvate-protein phosphotransferase PtsI; |
367-773 |
4.97e-32 |
|
phosphoenolpyruvate-protein phosphotransferase PtsI;
Pssm-ID: 183017 [Multi-domain] Cd Length: 575 Bit Score: 132.06 E-value: 4.97e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 367 IGSgtvRVLDSIDEMDKVQQGDI-----LV-TDMTDPDWEPI-MKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNAT 439
Cdd:PRK11177 133 IGK---RLLKNILGLKIIDLSAIqeeviLVaADLTPSETAQLnLKKVLGFITDIGGRTSHTSIMARSLELPAIVGTGNIT 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 440 DLIKAGqDVTVSCAEGDTGYI--YEGILD--------YEVLTSRVDEMPELP--------MKVMMNVGNPdRAFDFARLP 501
Cdd:PRK11177 210 KQVKNG-DYLILDAVNNQIYVnpTNEVIEelkavqeqYASEKAELAKLKDLPaitldghqVEVCANIGTV-RDVEGAERN 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 502 HA-GVGLARVEFV-INRmigvhpkallnfdaqsDELKAEiSEMMAGYESPVEfyisklvegiatlgcAFAPERVIVRMSD 579
Cdd:PRK11177 288 GAeGVGLYRTEFLfMDR----------------DALPTE-EEQFQAYKAVAE---------------AMGSQAVIVRTMD 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 580 F---KSNEYANLvggqqyePEEENPMIGFRgAARyISEDFRDCFALECEAIKRVRnemGMTNIEIMIPFVRTLEEG---K 653
Cdd:PRK11177 336 IggdKELPYMNL-------PKEENPFLGWR-AIR-IAMDRKEILHDQLRAILRAS---AFGKLRIMFPMIISVEEVrelK 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 654 RVIELLE----EHGLKRGENgLKVIMMCELPSNALLADEFLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHLFDERNPAIK 729
Cdd:PRK11177 404 AEIEILKqelrDEGKAFDES-IEIGVMVETPAAAVIARHLAKEVDFFSIGTNDLTQYTLAVDRGNELISHLYNPMSPSVL 482
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 1675102822 730 KLLSMAIQTAKAKGKYVGICGQGPSDhEDFAAWLVEQGIDSVSL 773
Cdd:PRK11177 483 NLIKQVIDASHAEGKWTGMCGELAGD-ERATLLLLGMGLDEFSM 525
|
|
| PRK05878 |
PRK05878 |
pyruvate phosphate dikinase; Provisional |
12-480 |
7.77e-27 |
|
pyruvate phosphate dikinase; Provisional
Pssm-ID: 235635 [Multi-domain] Cd Length: 530 Bit Score: 115.61 E-value: 7.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 12 GMQDVPR--VGGKNASLGEMISNlanaGVQVPGGFATTADAFNEFLEQSGlnSKIHDILDTLdVDDVNTLAKV------- 82
Cdd:PRK05878 14 GGANQPRelLGGKGHGIDMMRRL----GLPVPPAFCITTEVCVRYLADPG--STIDAIWDDV-LDRMRWLEAEtgrtfgr 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 83 -----------GAEIRQ-WIIDTPfqpnLDQAIRDAYSQLHGDASQDVSFAV----RSSATAEDMPDASFAGQQETFLNV 146
Cdd:PRK05878 87 gprpllvsvrsGAAQSMpGMMDTI----LNLGINDAVEQALAAEGGDPDFAAdtrrRFTEMYRRIVGSGSPPPDDPYEQL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 147 RGidavmtAIKHVFASLFNDRAISYRVHQGYDHR-GVALSagIQRMV---RSDKAASGVMFSIDTESGfEDVVFVT-SSY 221
Cdd:PRK05878 163 RA------AIEAVFASWNSPRAVAYRRHHGLDDDgGTAVV--VQAMVfgnLDANSGTGVLFSRNPITG-ANEPFGEwLPG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 222 GLGEMVVQGAVNPDefyvHKPTLANGKPAVVRrnigskaiqmiysadeshgkqveivdvdsslsnkfsitdaevqELAKQ 301
Cdd:PRK05878 234 GQGEDVVSGLVDVA----PITALRDEQPAVYD-------------------------------------------ELMAA 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 302 AVIIEKHYGRPMDIEWAKDgnDGKLYIVQARP------------------------ETVR--SNEDANVMERFQLNGT-- 353
Cdd:PRK05878 267 ARTLERLGRDVQDIEFTVE--SGKLWLLQTRSakrsaqaavrlalqlhdegliddaEALRrvTPTHVETLLRPSLQPEar 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 354 --STVVAEGRAIGHKIGSGTVrVLDSIDEMDKVQQGD--ILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGI 429
Cdd:PRK05878 345 laAPLLAKGLPACPGVVSGTA-YTDVDEALDAADRGEpvILVRDHTRPDDVHGMLAAQGIVTEVGGATSHAAVVSRELGR 423
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 1675102822 430 PAVVGCGNATDLIKAGQDVTVscaEGDTGYIYEGILdyEVLTSRVDEMPEL 480
Cdd:PRK05878 424 VAVVGCGAGVAAALAGKEITV---DGYEGEVRQGVL--ALSAWSESDTPEL 469
|
|
| PRK08296 |
PRK08296 |
hypothetical protein; Provisional |
333-466 |
1.23e-26 |
|
hypothetical protein; Provisional
Pssm-ID: 181362 Cd Length: 603 Bit Score: 115.52 E-value: 1.23e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 333 PETVR---SNEDANVMErfqLNGT--STVVAEGRAighkigsgtvRVLDSIDEMDKVQQGDILVTDMTDPDWEPIMKRAA 407
Cdd:PRK08296 483 TERVQdwlGLEDGAEGE---LKGFaaSPGVVEGPA----------RVIRSADELSEVQEGEILVCPVTSPSWAPIFAKIK 549
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1675102822 408 AIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTVscaEGDTGYIYegILD 466
Cdd:PRK08296 550 ATVTDIGGVMSHAAIVCREYGLPAVVGTGNATKRIKTGQRLRV---DGTKGVVT--ILD 603
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
354-463 |
4.19e-25 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 110.79 E-value: 4.19e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 354 STVVAEGRAIGHKIGSGTVRVLDSIDEMDKVQQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVV 433
Cdd:PRK06354 479 GAVVAKGQGIGRKSVSGKARVAKTAAEVAKVNEGDILVTPSTDADMIPAIEKAAAIITEEGGLTSHAAVVGLRLGIPVIV 558
|
90 100 110
....*....|....*....|....*....|
gi 1675102822 434 GCGNATDLIKAGQDVTVSCAEGDtgyIYEG 463
Cdd:PRK06354 559 GVKNATSLIKDGQIITVDAARGV---VYSG 585
|
|
| PRK06241 |
PRK06241 |
phosphoenolpyruvate synthase; Validated |
357-460 |
7.82e-23 |
|
phosphoenolpyruvate synthase; Validated
Pssm-ID: 235751 [Multi-domain] Cd Length: 871 Bit Score: 104.59 E-value: 7.82e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 357 VAEGRAighkigsgtvRVLDSIdEMDKVQQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCG 436
Cdd:PRK06241 777 VVEGRA----------RVILNP-EDADLEKGDILVTAFTDPGWTPLFVSIKGLVTEVGGLMTHGAVIAREYGIPAVVGVE 845
|
90 100
....*....|....*....|....
gi 1675102822 437 NATDLIKAGQDVTVscaEGDTGYI 460
Cdd:PRK06241 846 NATKLIKDGQRIRV---DGTEGYV 866
|
|
| PRK11061 |
PRK11061 |
phosphoenolpyruvate--protein phosphotransferase; |
404-778 |
9.33e-22 |
|
phosphoenolpyruvate--protein phosphotransferase;
Pssm-ID: 182937 [Multi-domain] Cd Length: 748 Bit Score: 100.84 E-value: 9.33e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 404 KRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQDVTvscaEGDTGYI-----------YEGILDYE-VLT 471
Cdd:PRK11061 341 DRLAGVVVRDGAANSHAAILVRALGIPTVMGADIQPSLLHQRLLIV----DGYRGELlvdpepvllqeYQRLISEEiELS 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 472 SRVDEMPELP--------MKVMMNVG-NPDRAFDFARLPHaGVGLARVEFVInrmigvhpkaLLNFDAQSDElkaeisEM 542
Cdd:PRK11061 417 RLAEDDVNLPaqlksgerIKVMLNAGlSAEHEEKLGSRVD-GVGLYRTEIPF----------MLQSGFPSEE------EQ 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 543 MAGYESPVEFYISKlvegiatlgcafapeRVIVRMSDfksneyanlVGGQQ---YEP-EEENPMIGFRGAAryISEDFRD 618
Cdd:PRK11061 480 VAQYQGMLQMFPDK---------------PVTLRTLD---------IGADKqlpYMPiSEENPCLGWRGIR--ITLDQPE 533
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 619 CFALECEAIKRVRNEMGmtNIEIMIPFVRTLEE---GKRVI-----ELLEEHG--LKRGENGlkviMMCELPSNALLADE 688
Cdd:PRK11061 534 IFLIQVRAMLRANAATG--NLSILLPMVTSIDEvdeARRLIdragrEVEEMLGyeIPKPRIG----IMIEVPSMVFMLPH 607
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 689 FLEYFDGFSIGSNDLTQLTLGLDRDSGLIAHLFDERNPAIKKLLSMAIQTAKAKGKYVGICGQGPSDHEDfAAWLVEQGI 768
Cdd:PRK11061 608 LASRVDFISVGTNDLTQYLLAVDRNNTRVASLYDSLHPAMLRALKMIADEAEQHGLPVSLCGEMAGDPMG-ALLLIGLGY 686
|
410
....*....|
gi 1675102822 769 DSVSLNPDTV 778
Cdd:PRK11061 687 RHLSMNGRSV 696
|
|
| PRK05865 |
PRK05865 |
sugar epimerase family protein; |
370-460 |
2.93e-10 |
|
sugar epimerase family protein;
Pssm-ID: 235630 [Multi-domain] Cd Length: 854 Bit Score: 63.91 E-value: 2.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 370 GTVRVL--DSIDEMdkvQQGDILVTDMTDPDWEPIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCGNATDLIKAGQD 447
Cdd:PRK05865 748 GRVRIVrpETIDDL---QPGEILVAEVTDVGYTAAFCYAAAVVTELGGPMSHAAVVAREFGFPCVVDAQGATRFLPPGAL 824
|
90
....*....|...
gi 1675102822 448 VTVscaEGDTGYI 460
Cdd:PRK05865 825 VEV---DGATGEI 834
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
121-342 |
4.24e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 60.00 E-value: 4.24e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 121 AVRSSATAEDMPDASFAGQQETFLNVRG--IDAVMTAIKHVFASLfndraisyrvhqGYDHRGVALsagIQRMVRsDKAA 198
Cdd:PRK05849 59 IVRSSSRSEDSSSSSNAGAFLSILNVNAdsKDQLLKAIEKVIASY------------GTSKDDEIL---VQPMLE-DIVL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1675102822 199 SGVMFSIDTESGFEDVVfvtssyglgemvvqgaVNPDEfyvhkptlaNGKPAVVRRNIGSKAIQMIYSADESHGKQVEIv 278
Cdd:PRK05849 123 SGVAMSRDPESGAPYYV----------------INYDE---------SGSTDSVTSGSGGSATTVYHYRDALVFKPPRL- 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1675102822 279 dvdsslsnkfsitdAEVQELAKQaviIEKHYGR-PMDIEWAKDGNdGKLYIVQARPETVRSNEDA 342
Cdd:PRK05849 177 --------------KKLIELIRE---LEALFGCdFLDIEFAIDEK-EELYILQVRPITVPEKWNA 223
|
|
| PRK05849 |
PRK05849 |
hypothetical protein; Provisional |
363-436 |
7.84e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 235623 [Multi-domain] Cd Length: 783 Bit Score: 49.60 E-value: 7.84e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1675102822 363 IGHKIGSGTVRVLDSIDEMDkvQQGDILVTDMTDP--DWePIMKRAAAIVTNRGGRTCHAAIIARELGIPAVVGCG 436
Cdd:PRK05849 686 ITQKRVEATVADLDNDNDDD--LEGKIVCIENADPgyDW-LFTKGIAGLITCYGGANSHMAIRAAELGLPAVIGVG 758
|
|
| PRK11377 |
PRK11377 |
dihydroxyacetone kinase subunit M; Provisional |
413-455 |
2.57e-04 |
|
dihydroxyacetone kinase subunit M; Provisional
Pssm-ID: 183108 [Multi-domain] Cd Length: 473 Bit Score: 44.36 E-value: 2.57e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1675102822 413 RGGRTC-HAAIIARELGIPAVVGCGNATDLIKAGQDVTVSCAEG 455
Cdd:PRK11377 424 SAGSPLsHSAIIARELGIGWICQQGEKLYAIQPEETLTLDVKTQ 467
|
|
| |
