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Conserved domains on  [gi|1692764217|ref|WP_139896850|]
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MULTISPECIES: carbohydrate ABC transporter permease [Enterococcus]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
5-271 6.62e-101

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 295.85  E-value: 6.62e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   5 QWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT 84
Cdd:COG0395    14 RILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  85 SSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAF--NAFGVFLLKQYYSSIPDS 162
Cdd:COG0395    94 SSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRE 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 163 LCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAAS 242
Cdd:COG0395   174 LEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAA 253
                         250       260
                  ....*....|....*....|....*....
gi 1692764217 243 VVSVLPVAFIFLAMQKYFVEGIASSGMKE 271
Cdd:COG0395   254 VIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
5-271 6.62e-101

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 295.85  E-value: 6.62e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   5 QWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT 84
Cdd:COG0395    14 RILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  85 SSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAF--NAFGVFLLKQYYSSIPDS 162
Cdd:COG0395    94 SSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRE 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 163 LCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAAS 242
Cdd:COG0395   174 LEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAA 253
                         250       260
                  ....*....|....*....|....*....
gi 1692764217 243 VVSVLPVAFIFLAMQKYFVEGIASSGMKE 271
Cdd:COG0395   254 VIATLPVLILFLFLQRYFVRGLTAGAVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
11-267 3.98e-30

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 114.06  E-value: 3.98e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  11 LLIVLALLTIIPFLWMVSASFKANNEVFTIPIQWIPKTWHLENYLVIWSR------IPLVTFFKNTAFLSVVITLIQLFT 84
Cdd:PRK10973   15 MLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVNgvgnnsAPFGRMLLNSFVMAFSITVGKITV 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  85 SSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNAFGVFLLKQYYSSIPDSLC 164
Cdd:PRK10973   95 SMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELV 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 165 ESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDA--EYALIMAAS 242
Cdd:PRK10973  175 EAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEGttEWNQVMAAM 254
                         250       260
                  ....*....|....*....|....*
gi 1692764217 243 VVSVLPVAFIFLAMQKYFVEGIASS 267
Cdd:PRK10973  255 LLTLIPPVVIVLAMQRAFVRGLVDS 279
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
67-249 1.69e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 1.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  67 FKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVG-----LTYTLWTLVLL 141
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgilPGLGLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 142 QAFN-AFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTI 220
Cdd:cd06261    81 LLLIaPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                         170       180
                  ....*....|....*....|....*....
gi 1692764217 221 QLGLKMFIGLFDAEYALIMAASVVSVLPV 249
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
94-261 6.84e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.15  E-value: 6.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  94 KLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNAFGVFLL--KQYYSSIPDSLCESARIDG 171
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLirRAALRSLPSDLVEAARALG 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 172 LSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGP-FIYLSSTENKTIQLGLkmfIGLFDAEYALIMAASVVSVLPVA 250
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLeFLGSWPGLGLLLIEAI---LGYDYPEIQGPVLAAALILLLLN 167
                         170
                  ....*....|.
gi 1692764217 251 FIFLAMQKYFV 261
Cdd:pfam00528 168 LLVDILQRLLD 178
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
5-271 6.62e-101

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 295.85  E-value: 6.62e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   5 QWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT 84
Cdd:COG0395    14 RILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  85 SSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAF--NAFGVFLLKQYYSSIPDS 162
Cdd:COG0395    94 SSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAfgLPFGIFLLRQFFRSIPRE 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 163 LCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAAS 242
Cdd:COG0395   174 LEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASFQGQYGTDWGLLMAAA 253
                         250       260
                  ....*....|....*....|....*....
gi 1692764217 243 VVSVLPVAFIFLAMQKYFVEGIASSGMKE 271
Cdd:COG0395   254 VIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
6-271 7.06e-62

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 196.53  E-value: 7.06e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   6 WLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIqwIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTS 85
Cdd:COG3833    16 GLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSL--IPENFTLENYKKLFTETPFLRWFLNSLIVAVVTAIISVFLA 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  86 SFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNA--FGVFLLKQYYSSIPDSL 163
Cdd:COG3833    94 ALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAipFNTWLMKGYFDTIPKEL 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 164 CESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLGLKMFI-GLFDAEYALIMAAS 242
Cdd:COG3833   174 DEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVsDQRNTNWGVFAAGA 253
                         250       260
                  ....*....|....*....|....*....
gi 1692764217 243 VVSVLPVAFIFLAMQKYFVEGIASSGMKE 271
Cdd:COG3833   254 VLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
11-267 3.98e-30

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 114.06  E-value: 3.98e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  11 LLIVLALLTIIPFLWMVSASFKANNEVFTIPIQWIPKTWHLENYLVIWSR------IPLVTFFKNTAFLSVVITLIQLFT 84
Cdd:PRK10973   15 MLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVNgvgnnsAPFGRMLLNSFVMAFSITVGKITV 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  85 SSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNAFGVFLLKQYYSSIPDSLC 164
Cdd:PRK10973   95 SMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELV 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 165 ESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDA--EYALIMAAS 242
Cdd:PRK10973  175 EAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEGttEWNQVMAAM 254
                         250       260
                  ....*....|....*....|....*
gi 1692764217 243 VVSVLPVAFIFLAMQKYFVEGIASS 267
Cdd:PRK10973  255 LLTLIPPVVIVLAMQRAFVRGLVDS 279
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
6-259 4.94e-19

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 84.01  E-value: 4.94e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   6 WLGMILLIVLALLtIIPFLWMVSASFkANNEVFTIPiqwiPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTS 85
Cdd:COG1177     8 LLRLFLALVLLFL-YLPILVLVLYSF-NDSWFLTFP----PEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLATVLG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  86 SFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNA--FGVFLLKQYYSSIPDSL 163
Cdd:COG1177    82 TPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTlpFVVLVVLARLQGFDPSL 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 164 CESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIyLSSTENKTiqLGLKMFIGLFDAEYALIMAASV 243
Cdd:COG1177   162 EEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLF-LAGPGVTT--LPVYIYSMIRRGISPEINALST 238
                         250
                  ....*....|....*.
gi 1692764217 244 VSVLPVAFIFLAMQKY 259
Cdd:COG1177   239 LLILLSLLLLLLAERL 254
malG PRK10998
maltose ABC transporter permease MalG;
6-270 2.17e-17

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 79.75  E-value: 2.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   6 WLGMILLIVLALLTIIPFLWMVSASFKANNevfTIPIQWIPKTWHLENY-------------LVIWSRIPLVTFFKNTAF 72
Cdd:PRK10998   14 FATHLLLLGFIALIMFPLLMVIAISLREGN---FATGSLIPEQISWEHWklalgfsvehadgRVTPPPFPVLLWLWNSVK 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  73 LSVVITLIQLFTSSFAAYGFSKLNFKGRDIL---------FLAYIGTIAVPWQSYMIPQFIMMrkVGLTYTLWTLVLLQA 143
Cdd:PRK10998   91 VAGITAIGIVALSTTCAYAFARMRFKGKATLlkgmlifqmFPAVLSLVALYALFDRLGQYIPF--IGLNTHGGVIFAYLG 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 144 FNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTIQLG 223
Cdd:PRK10998  169 GIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVG 248
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1692764217 224 LKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMK 270
Cdd:PRK10998  249 MQQYLNPQNYLWGDFAAAAVLSAIPITVVFLLAQRWLVGGLTAGGVK 295
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-259 4.58e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 68.65  E-value: 4.58e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   6 WLGMILLIVLALLTIIPFLWMVSASFkannevftipiqwipkTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTS 85
Cdd:COG1178    11 LLLLLLALLLALLVLLPLLALLLRAF----------------TDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLG 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  86 SFAAYGFSKLNFKGRDILFLAYIGTIAVP-------WQSYMIP----QFIMMRKVGLT----YTLWTLVLLQAFNAFGV- 149
Cdd:COG1178    75 VPLAWLLARTDFPGRRLLRWLLLLPLALPpyvvalaWIALFGPngllNTLLRALFGLEppdiYGLGGIILVLVLFNYPYv 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 150 -FLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYlsSTENKTIQLGL-KMF 227
Cdd:COG1178   155 yLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL--GGGYTTLTTAIyQAW 232
                         250       260       270
                  ....*....|....*....|....*....|..
gi 1692764217 228 IGLFDAEYAliMAASVVSVLPVAFIFLAMQKY 259
Cdd:COG1178   233 LGDFDLGAA--AALALVLLLLVLLLLLLERRL 262
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
6-260 1.05e-12

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 66.32  E-value: 1.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   6 WLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIqwipkTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTS 85
Cdd:COG1176    13 LLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVP-----GFTLENYARLFTDPLYLKVLLRTLWIALLTTLICLLLG 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  86 SFAAYGFSKLNFKGRDILFLAYIgtiaVP-WQSYMIPQFIMM--------------------RKVGLTYTLW--TLVLLQ 142
Cdd:COG1176    88 YPIAYFLARAPPRWRNLLLLLVI----LPfWTSFLVRTYAWIvllgrngllnslllalglidEPLRLLYTEFavVIGLVY 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 143 AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIyLSSTENKTI-Q 221
Cdd:COG1176   164 VYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPAL-LGGGKVLMIgN 242
                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1692764217 222 LGLKMFIGLFDaeYALIMAASVVSVLPVAFIFLAMQKYF 260
Cdd:COG1176   243 LIYQQFLSALN--WPLAAALAVVLLLIVLLVLLLYLRLL 279
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
12-210 1.58e-12

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 65.93  E-value: 1.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  12 LIVLALLTIIPFLWMVSASFkANNEVFTIPIQWIPktwhLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYG 91
Cdd:COG1175    28 LLLLLVFVLYPLLYTLYLSF-TDWNLLGPPPEFVG----LDNYARLFTDPRFWNALGNTLLFTVVSVPLQLVLGLLLALL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  92 FSKlNFKGRDILFLAYIGTIAVP-------WQSYMIPQF----IMMRKVGLT---------YTLWTLVLLQAFNAFG-VF 150
Cdd:COG1175   103 LNR-KLRGRGFFRTLFFLPWVISpvvvaliWKWLFNPDYgllnALLGALGLEpinwlgdpsLALPAVIIVTVWKGTGfNM 181
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1692764217 151 LLkqYYS---SIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFI 210
Cdd:COG1175   182 LI--FLAglqSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDLVYV 242
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-258 3.63e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 65.95  E-value: 3.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   5 QWLGMILLIVLALLTII-PFLWMVSASFKAnnevftipiqWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLF 83
Cdd:COG1178   287 RWLALALCLLLVLLGLLlPLLALLLWSLTK----------ALDDNLTLDNYRFVLLDPSLLRALLNSLLLALLAALLAVL 356
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  84 TSSFAAYGFSKLNFKGRDIL-FLAYIG------TIAVpwqSYMIPqFIMMRKVGLTYTLWTLVLLQA--FNAFGVFLLKQ 154
Cdd:COG1178   357 LALLLAYLVRRRRGRLARLLdRLAMLPyavpgiVLGL---GLLLL-FNRPLPLLLYGTLAILVLAYVvrFLPFALRSLEA 432
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 155 YYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYmGPFIYLSSTENKTiqLGLKMFIGLFDAE 234
Cdd:COG1178   433 ALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKEL-SATLLLRPPGFET--LAVLIYQLASSGR 509
                         250       260
                  ....*....|....*....|....
gi 1692764217 235 YALIMAASVVSVLPVAFIFLAMQK 258
Cdd:COG1178   510 YGEAAALALLLVLVSLLPVLLLER 533
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
67-249 1.69e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.53  E-value: 1.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  67 FKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVG-----LTYTLWTLVLL 141
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgilPGLGLPALILA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 142 QAFN-AFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENKTI 220
Cdd:cd06261    81 LLLIaPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160
                         170       180
                  ....*....|....*....|....*....
gi 1692764217 221 QLGLKMFIGLFDAEYALIMAASVVSVLPV 249
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
94-261 6.84e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 51.15  E-value: 6.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  94 KLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNAFGVFLL--KQYYSSIPDSLCESARIDG 171
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLirRAALRSLPSDLVEAARALG 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217 172 LSEWEIYRKIILPLTKPAIASLTIITFVNTWNDYMGP-FIYLSSTENKTIQLGLkmfIGLFDAEYALIMAASVVSVLPVA 250
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLeFLGSWPGLGLLLIEAI---LGYDYPEIQGPVLAAALILLLLN 167
                         170
                  ....*....|.
gi 1692764217 251 FIFLAMQKYFV 261
Cdd:pfam00528 168 LLVDILQRLLD 178
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
3-198 1.21e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 42.43  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   3 FIQWLGmILLIVLALLTIIPFLWMVSASFKANNEVFtipiqwipktWHlenylVIWSriPLVTF-FKNTAFLSVVITLIQ 81
Cdd:COG0555     9 FGLTLG-LTLLYLSLIVLLPLAALVLKAAGLGWAEF----------WA-----VLTS--PRVLAaLKLSLGTALIAALIN 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  82 LFTSSFAAYGFSKLNFKGRDIL------------FLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLLQAFNA--F 147
Cdd:COG0555    71 LVFGLPLAWVLVRYRFPGKRLVdalvdlpfalptAVAGIALLLLFGPNGWLGQLLAPLGIKVAFTPLGIVLAQTFVSlpF 150
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1692764217 148 GVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITF 198
Cdd:COG0555   151 VVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAF 201
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
6-192 2.23e-04

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 41.51  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217   6 WLGMILLIVLALLTIIPFLWMVSASFKANNevftIPIQWIPKTWHLenYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTS 85
Cdd:PRK09500    4 LLRGGFMTLVYAYLYIPIIILIVNSFNSSR----FGINWKGFTTKW--YELLFNNDSLLQAAQHSLTMAVFSATFATLIG 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1692764217  86 SFAAYGFSKLNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWTLVLlqAFNAFGV-FLLKQYYSSIPD--- 161
Cdd:PRK09500   78 SLTAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLF--AHITFCLpFVVVTVYSRLKGfdv 155
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1692764217 162 SLCESARIDGLSEWEIYRKIILPLTKPAIAS 192
Cdd:PRK09500  156 RMLEAAKDLGASEFTILRKIILPLALPAVAA 186
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
133-205 3.70e-03

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 38.06  E-value: 3.70e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1692764217 133 YTLWTLVLLQA--FNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVNTWNDY 205
Cdd:PRK15050  159 YSPGGVILAEItfYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEF 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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