NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1697803351|ref|WP_141281224|]
View 

cytochrome c biogenesis protein ResB [Paenarthrobacter aurescens]

Protein Classification

cytochrome c biogenesis protein ResB( domain architecture ID 10003552)

cytochrome c biogenesis protein ResB (also called CcsB and Ccs1) is essential for the biogenesis of c-type cytochromes, and may be required at the heme attachment step

Gene Ontology:  GO:0017004|GO:0016020
PubMed:  9395519

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
ResB COG1333
Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational ...
34-542 0e+00

Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440944  Cd Length: 479  Bit Score: 576.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  34 PALGFKGMLRWAWTQLTSMRTALFLLLLLAVGAVPGSLFPQRPANPVTVTDWIKNN-PTTGPFLDALQMFDVYSSAWFSA 112
Cdd:COG1333     3 PALGLRGWLRWAWRQLTSMRTALFLLLLLAVAAIPGTLLPQRSPDPAGVTQYLADYgPTLGPILDRLGLFDVYSSWWFSA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 113 IYILLFISLIGCVTPRAIAHYKAMKSQPPRTPKR-LSRLPEYGTLAVPADAGipasKAIADAAGLLKKRGYRVEVRDVDG 191
Cdd:COG1333    83 IYLLLFISLIGCSIPRLPPHWKALRAQPPRTPRRfLKRLPHHAELTVDASPD----EVLERAAALLRKRGYRVREREDDG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 192 AlPSLGAERGFLKEVGNLVFHTSLIGVLVSVAIGGLYGYSGQRILVEGDTFVnTLVGYDQftpgtnFQSSWLQPYSMQLD 271
Cdd:COG1333   159 G-VSVSAEKGYLRELGNLVFHLSLLGILIGVALGSLFGYRGQVIVVEGETFA-TLVGYDS------FDGDQLLPFSVRLD 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 272 KFQATFDRGespgkaGQPIDYTAEVTTKETKDSAGKKEILKVNDPVSLGGTSLYLTGNGYAPMVTVRDGEGNVSFEGPVI 351
Cdd:COG1333   231 DFTVEYYDN------GQPKDFQSDVTVTEGGGGEVKEATIRVNHPLRYDGYRVYQSGYGYAPSVTVRDKDGGVVFGGPVP 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 352 AKVQGDnyyssvVIKVPD-AKPDQLGFVgFFLPTAFSGENGTSFSASPELFNPQLSLNSFYGDLGLDKGVPqnvfeldvk 430
Cdd:COG1333   305 FLPQDS------SIKVPDnGLPEQLGLE-FFLPTAALDGDGVPTSKSPDPNNPALVLKVYRGDLGLDTGVP--------- 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 431 nlkplnardlaaGGITLTPGATVDLPDGKGSITFD--GVKKYIGVDIHHNPGQLYALIFGFLAVAGLVMSLYINRRRVWV 508
Cdd:COG1333   369 ------------ARSFLAPGQTVELPDGLGTITFDgfGVKRFTGLQVSKDPGQPLVLLGAILLLLGLILSLYVRRRRVWV 436
                         490       500       510
                  ....*....|....*....|....*....|....
gi 1697803351 509 RTGTHADGRTMVEYGLLARGEDHRLAGEAAALRE 542
Cdd:COG1333   437 RVTPDGDGGTVVEVAGLARKNDAGLEKEFDRLAA 470
 
Name Accession Description Interval E-value
ResB COG1333
Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational ...
34-542 0e+00

Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440944  Cd Length: 479  Bit Score: 576.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  34 PALGFKGMLRWAWTQLTSMRTALFLLLLLAVGAVPGSLFPQRPANPVTVTDWIKNN-PTTGPFLDALQMFDVYSSAWFSA 112
Cdd:COG1333     3 PALGLRGWLRWAWRQLTSMRTALFLLLLLAVAAIPGTLLPQRSPDPAGVTQYLADYgPTLGPILDRLGLFDVYSSWWFSA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 113 IYILLFISLIGCVTPRAIAHYKAMKSQPPRTPKR-LSRLPEYGTLAVPADAGipasKAIADAAGLLKKRGYRVEVRDVDG 191
Cdd:COG1333    83 IYLLLFISLIGCSIPRLPPHWKALRAQPPRTPRRfLKRLPHHAELTVDASPD----EVLERAAALLRKRGYRVREREDDG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 192 AlPSLGAERGFLKEVGNLVFHTSLIGVLVSVAIGGLYGYSGQRILVEGDTFVnTLVGYDQftpgtnFQSSWLQPYSMQLD 271
Cdd:COG1333   159 G-VSVSAEKGYLRELGNLVFHLSLLGILIGVALGSLFGYRGQVIVVEGETFA-TLVGYDS------FDGDQLLPFSVRLD 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 272 KFQATFDRGespgkaGQPIDYTAEVTTKETKDSAGKKEILKVNDPVSLGGTSLYLTGNGYAPMVTVRDGEGNVSFEGPVI 351
Cdd:COG1333   231 DFTVEYYDN------GQPKDFQSDVTVTEGGGGEVKEATIRVNHPLRYDGYRVYQSGYGYAPSVTVRDKDGGVVFGGPVP 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 352 AKVQGDnyyssvVIKVPD-AKPDQLGFVgFFLPTAFSGENGTSFSASPELFNPQLSLNSFYGDLGLDKGVPqnvfeldvk 430
Cdd:COG1333   305 FLPQDS------SIKVPDnGLPEQLGLE-FFLPTAALDGDGVPTSKSPDPNNPALVLKVYRGDLGLDTGVP--------- 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 431 nlkplnardlaaGGITLTPGATVDLPDGKGSITFD--GVKKYIGVDIHHNPGQLYALIFGFLAVAGLVMSLYINRRRVWV 508
Cdd:COG1333   369 ------------ARSFLAPGQTVELPDGLGTITFDgfGVKRFTGLQVSKDPGQPLVLLGAILLLLGLILSLYVRRRRVWV 436
                         490       500       510
                  ....*....|....*....|....*....|....
gi 1697803351 509 RTGTHADGRTMVEYGLLARGEDHRLAGEAAALRE 542
Cdd:COG1333   437 RVTPDGDGGTVVEVAGLARKNDAGLEKEFDRLAA 470
ResB pfam05140
ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. ...
52-536 9.13e-156

ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.


Pssm-ID: 428331  Cd Length: 445  Bit Score: 453.21  E-value: 9.13e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  52 MRTALFLLLLLAVGAVPGSLFPQRPANPVTVTDWIKNNPTTGPFLDALQMFDVYSSAWFSAIYILLFISLIGCVTPRAIA 131
Cdd:pfam05140   1 MRTALVLLFLLAIASIPGTVLPQRQPSLNYVAQYIADGPFWAPWFDRLGLFDVYSSWWFLAIYLLLFVSLVGCILPRLPP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 132 HYKAMKSQ-PPRTPKRLSRLPEYGTLAVPAdagiPASKAIADAAGLLKKRGYRVEVRDVDGalpSLGAERGFLKEVGNLV 210
Cdd:pfam05140  81 HLRALRSQrPPRAPRRLKRLPHHAEFEVAD----APEEAAERAAALLKRRGYRVRVEEGGG---SLAAEKGYLRRLGNLV 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 211 FHTSLIGVLVSVAIGGLYGYSGQRILVEGDTFVNTLVGydQFTPGTNFQSSwlqPYSMQLDKFQATFDRGespgkaGQPI 290
Cdd:pfam05140 154 FHLALLVILVGGLLGSLFGYRGNVIVPEGQGFCNTFLA--SFRDGALVDPL---PFSVRLDKFTVEYYDT------GQPK 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 291 DYTAEVTTKETKDSAGKKEILKVNDPVSLGGTSLYLTGNGYAPMVTVRDGEGNVsFEGPViakVQGDNYYSSVVIKVpda 370
Cdd:pfam05140 223 SFESDVTVTDGGKGEVREATIRVNHPLRYDGVRVYQSSYGPAPVFTVRDPDGEV-RTGPV---PQDGNFTSSGVRKP--- 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 371 kpdQLGFVGFFLPTAFSGENgtSFSASPELFNPQLSLNSFYGDLGLDKGVPQNVFELDVKNLKPLNARDLAAGGITLTPg 450
Cdd:pfam05140 296 ---QLAFQGLFLPTAALGEG--FLSLFPALNDPALALDAYRGDLGLDAGGPQSVYSLDTTLFELGQLNADRYGAPYLLP- 369
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 451 atvdLPDgkgsitFDgVKKYIGVDIHHNPGQLYALIFGFLAVAGLVMSLYINRRRVWVRTgTHADGRTMVEYGLLARGED 530
Cdd:pfam05140 370 ----LDD------FD-VKQFSGLQVSRDPGQPLVLVGAVLLVLGLFLSLYVRHRRVWVRV-TPGDGGTVVEVAGLARKNW 437

                  ....*.
gi 1697803351 531 HRLAGE 536
Cdd:pfam05140 438 AGFGEE 443
ccs1 CHL00177
c-type cytochrome biogenensis protein; Validated
87-242 1.58e-04

c-type cytochrome biogenensis protein; Validated


Pssm-ID: 214387 [Multi-domain]  Cd Length: 426  Bit Score: 44.25  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  87 KNNPTTGPFL-----DALQMF---DVYSSAWFSAIYILLFISLIGCVTPRAIAHYK-AMKSQPPRTPKRLSRLPEYGTLa 157
Cdd:CHL00177   45 NNYPLSNPIFgflswKIILKLgldHIYKTWWFLSLLLLFGLSLLLCTLLQQLPSLKiARRWQFYTNKNQFKKLQISTNL- 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 158 vpadagipASKAIADAAGLLKKRGYRVEVRDvdgalPSLGAERGFLKEVGNLVFHTSLIGVLVSVAIGGLYGYSGQRILV 237
Cdd:CHL00177  124 --------KKFSLSKLAYKLKSKNYSIFQQG-----NKIYAYKGLIGRIAPIIVHFSMILILIGSILGALSGFTAQEIIP 190

                  ....*
gi 1697803351 238 EGDTF 242
Cdd:CHL00177  191 KTEIF 195
 
Name Accession Description Interval E-value
ResB COG1333
Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational ...
34-542 0e+00

Cytochrome c biogenesis protein ResB [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440944  Cd Length: 479  Bit Score: 576.44  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  34 PALGFKGMLRWAWTQLTSMRTALFLLLLLAVGAVPGSLFPQRPANPVTVTDWIKNN-PTTGPFLDALQMFDVYSSAWFSA 112
Cdd:COG1333     3 PALGLRGWLRWAWRQLTSMRTALFLLLLLAVAAIPGTLLPQRSPDPAGVTQYLADYgPTLGPILDRLGLFDVYSSWWFSA 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 113 IYILLFISLIGCVTPRAIAHYKAMKSQPPRTPKR-LSRLPEYGTLAVPADAGipasKAIADAAGLLKKRGYRVEVRDVDG 191
Cdd:COG1333    83 IYLLLFISLIGCSIPRLPPHWKALRAQPPRTPRRfLKRLPHHAELTVDASPD----EVLERAAALLRKRGYRVREREDDG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 192 AlPSLGAERGFLKEVGNLVFHTSLIGVLVSVAIGGLYGYSGQRILVEGDTFVnTLVGYDQftpgtnFQSSWLQPYSMQLD 271
Cdd:COG1333   159 G-VSVSAEKGYLRELGNLVFHLSLLGILIGVALGSLFGYRGQVIVVEGETFA-TLVGYDS------FDGDQLLPFSVRLD 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 272 KFQATFDRGespgkaGQPIDYTAEVTTKETKDSAGKKEILKVNDPVSLGGTSLYLTGNGYAPMVTVRDGEGNVSFEGPVI 351
Cdd:COG1333   231 DFTVEYYDN------GQPKDFQSDVTVTEGGGGEVKEATIRVNHPLRYDGYRVYQSGYGYAPSVTVRDKDGGVVFGGPVP 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 352 AKVQGDnyyssvVIKVPD-AKPDQLGFVgFFLPTAFSGENGTSFSASPELFNPQLSLNSFYGDLGLDKGVPqnvfeldvk 430
Cdd:COG1333   305 FLPQDS------SIKVPDnGLPEQLGLE-FFLPTAALDGDGVPTSKSPDPNNPALVLKVYRGDLGLDTGVP--------- 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 431 nlkplnardlaaGGITLTPGATVDLPDGKGSITFD--GVKKYIGVDIHHNPGQLYALIFGFLAVAGLVMSLYINRRRVWV 508
Cdd:COG1333   369 ------------ARSFLAPGQTVELPDGLGTITFDgfGVKRFTGLQVSKDPGQPLVLLGAILLLLGLILSLYVRRRRVWV 436
                         490       500       510
                  ....*....|....*....|....*....|....
gi 1697803351 509 RTGTHADGRTMVEYGLLARGEDHRLAGEAAALRE 542
Cdd:COG1333   437 RVTPDGDGGTVVEVAGLARKNDAGLEKEFDRLAA 470
ResB pfam05140
ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. ...
52-536 9.13e-156

ResB-like family; This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.


Pssm-ID: 428331  Cd Length: 445  Bit Score: 453.21  E-value: 9.13e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  52 MRTALFLLLLLAVGAVPGSLFPQRPANPVTVTDWIKNNPTTGPFLDALQMFDVYSSAWFSAIYILLFISLIGCVTPRAIA 131
Cdd:pfam05140   1 MRTALVLLFLLAIASIPGTVLPQRQPSLNYVAQYIADGPFWAPWFDRLGLFDVYSSWWFLAIYLLLFVSLVGCILPRLPP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 132 HYKAMKSQ-PPRTPKRLSRLPEYGTLAVPAdagiPASKAIADAAGLLKKRGYRVEVRDVDGalpSLGAERGFLKEVGNLV 210
Cdd:pfam05140  81 HLRALRSQrPPRAPRRLKRLPHHAEFEVAD----APEEAAERAAALLKRRGYRVRVEEGGG---SLAAEKGYLRRLGNLV 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 211 FHTSLIGVLVSVAIGGLYGYSGQRILVEGDTFVNTLVGydQFTPGTNFQSSwlqPYSMQLDKFQATFDRGespgkaGQPI 290
Cdd:pfam05140 154 FHLALLVILVGGLLGSLFGYRGNVIVPEGQGFCNTFLA--SFRDGALVDPL---PFSVRLDKFTVEYYDT------GQPK 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 291 DYTAEVTTKETKDSAGKKEILKVNDPVSLGGTSLYLTGNGYAPMVTVRDGEGNVsFEGPViakVQGDNYYSSVVIKVpda 370
Cdd:pfam05140 223 SFESDVTVTDGGKGEVREATIRVNHPLRYDGVRVYQSSYGPAPVFTVRDPDGEV-RTGPV---PQDGNFTSSGVRKP--- 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 371 kpdQLGFVGFFLPTAFSGENgtSFSASPELFNPQLSLNSFYGDLGLDKGVPQNVFELDVKNLKPLNARDLAAGGITLTPg 450
Cdd:pfam05140 296 ---QLAFQGLFLPTAALGEG--FLSLFPALNDPALALDAYRGDLGLDAGGPQSVYSLDTTLFELGQLNADRYGAPYLLP- 369
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 451 atvdLPDgkgsitFDgVKKYIGVDIHHNPGQLYALIFGFLAVAGLVMSLYINRRRVWVRTgTHADGRTMVEYGLLARGED 530
Cdd:pfam05140 370 ----LDD------FD-VKQFSGLQVSRDPGQPLVLVGAVLLVLGLFLSLYVRHRRVWVRV-TPGDGGTVVEVAGLARKNW 437

                  ....*.
gi 1697803351 531 HRLAGE 536
Cdd:pfam05140 438 AGFGEE 443
ccs1 CHL00177
c-type cytochrome biogenensis protein; Validated
87-242 1.58e-04

c-type cytochrome biogenensis protein; Validated


Pssm-ID: 214387 [Multi-domain]  Cd Length: 426  Bit Score: 44.25  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351  87 KNNPTTGPFL-----DALQMF---DVYSSAWFSAIYILLFISLIGCVTPRAIAHYK-AMKSQPPRTPKRLSRLPEYGTLa 157
Cdd:CHL00177   45 NNYPLSNPIFgflswKIILKLgldHIYKTWWFLSLLLLFGLSLLLCTLLQQLPSLKiARRWQFYTNKNQFKKLQISTNL- 123
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1697803351 158 vpadagipASKAIADAAGLLKKRGYRVEVRDvdgalPSLGAERGFLKEVGNLVFHTSLIGVLVSVAIGGLYGYSGQRILV 237
Cdd:CHL00177  124 --------KKFSLSKLAYKLKSKNYSIFQQG-----NKIYAYKGLIGRIAPIIVHFSMILILIGSILGALSGFTAQEIIP 190

                  ....*
gi 1697803351 238 EGDTF 242
Cdd:CHL00177  191 KTEIF 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH