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Conserved domains on  [gi|1705116580|ref|WP_142484616|]
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phosphopyruvate hydratase [Klebsiella pneumoniae]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-428 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 815.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   1 MSfEIESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDAL 80
Cdd:COG0148     1 MS-RIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  81 QGYDVRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARWq 160
Cdd:COG0148    80 IGMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADN- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 161 GADFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIV 240
Cdd:COG0148   159 NVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIA 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 241 ICMDPASSEFYADGKYTLRTENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTN 320
Cdd:COG0148   239 LALDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 321 VKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERI 400
Cdd:COG0148   319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398

                         410       420
                  ....*....|....*....|....*...
gi 1705116580 401 EKYNQLMRIEDELGDAAIFAGKTAFKKR 428
Cdd:COG0148   399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-428 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 815.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   1 MSfEIESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDAL 80
Cdd:COG0148     1 MS-RIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  81 QGYDVRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARWq 160
Cdd:COG0148    80 IGMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADN- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 161 GADFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIV 240
Cdd:COG0148   159 NVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIA 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 241 ICMDPASSEFYADGKYTLRTENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTN 320
Cdd:COG0148   239 LALDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 321 VKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERI 400
Cdd:COG0148   319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398

                         410       420
                  ....*....|....*....|....*...
gi 1705116580 401 EKYNQLMRIEDELGDAAIFAGKTAFKKR 428
Cdd:COG0148   399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
eno PRK00077
enolase; Provisional
 3-428 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 760.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   3 FEIESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQG 82
Cdd:PRK00077    2 SKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  83 YDVRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARwQGA 162
Cdd:PRK00077   82 LDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHAD-NNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 163 DFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIVIC 242
Cdd:PRK00077  161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 243 MDPASSEFYADGKYTLRTENtqLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTNVK 322
Cdd:PRK00077  241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 323 YIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERIEK 402
Cdd:PRK00077  319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398

                         410       420
                  ....*....|....*....|....*.
gi 1705116580 403 YNQLMRIEDELGDAAIFAGKTAFKKR 428
Cdd:PRK00077  399 YNQLLRIEEELGDAARYAGKKAFKNL 424
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 7-412 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 694.61  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   7 SIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQGYDVR 86
Cdd:cd03313     1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  87 SQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARWqGADFQE 166
Cdd:cd03313    81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGN-KLDFQE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 167 FMIAPWGASSVREAIRWGSEVYQALRQVLLEKG--LSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIVICMD 244
Cdd:cd03313   160 FMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALD 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 245 PASSEFYADGKYTLRT-ENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTNVKY 323
Cdd:cd03313   240 VAASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 324 IQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERIEKY 403
Cdd:cd03313   320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399


                  ....*....
gi 1705116580 404 NQLMRIEDE 412
Cdd:cd03313   400 NQLLRIEEE 408
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 5-427 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 655.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   5 IESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQGYD 84
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  85 VRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARwQGADF 164
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHAD-NNLDF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 165 QEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIVICMD 244
Cdd:TIGR01060 160 QEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALD 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 245 PASSEFY--ADGKYTLRTENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTNVK 322
Cdd:TIGR01060 240 CAASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTE 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 323 YIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERIEK 402
Cdd:TIGR01060 320 ILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 399

                         410       420
                  ....*....|....*....|....*
gi 1705116580 403 YNQLMRIEDELGDAAIFAGKTAFKK 427
Cdd:TIGR01060 400 YNQLLRIEEELGDSARYAGKNSFYR 424
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
143-427 1.49e-136

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 393.38  E-value: 1.49e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 143 LPVPCMNIINGGVHARwQGADFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKG--LSTGVGDEGGFAPAVSSNRQP 220
Cdd:pfam00113   4 LPVPMMNVINGGSHAG-NNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 221 LELIVEAISKAGYRPgeDIVICMDPASSEFYA--DGKYTLRTENTQ------LSAEEMTRYYEQLVNDFPIVLIEDGLAE 292
Cdd:pfam00113  83 LDLIVEAIEKAGYKG--KIKIAMDVASSEFYNkkDGKYDLDFKGEKsdkskkLTSAQLADLYEELVKKYPIVSIEDPFDE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 293 DDWAGWKILHAALGGKVELVGDDIFVTNVKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGET 372
Cdd:pfam00113 161 DDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGET 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1705116580 373 VDSFIADMTVGLRAGHLKTGAPSRGERIEKYNQLMRIEDELGDAAIFAGKTAFKK 427
Cdd:pfam00113 241 EDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKP 295
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-428 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 815.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   1 MSfEIESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDAL 80
Cdd:COG0148     1 MS-RIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  81 QGYDVRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARWq 160
Cdd:COG0148    80 IGMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNAKTLPVPMMNIINGGAHADN- 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 161 GADFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIV 240
Cdd:COG0148   159 NVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGEDIA 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 241 ICMDPASSEFYADGKYTLRTENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTN 320
Cdd:COG0148   239 LALDVAASEFYKDGKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDLFVTN 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 321 VKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERI 400
Cdd:COG0148   319 PKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSRSERV 398

                         410       420
                  ....*....|....*....|....*...
gi 1705116580 401 EKYNQLMRIEDELGDAAIFAGKTAFKKR 428
Cdd:COG0148   399 AKYNQLLRIEEELGDAARYAGRSAFKRL 426
eno PRK00077
enolase; Provisional
 3-428 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 760.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   3 FEIESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQG 82
Cdd:PRK00077    2 SKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALIG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  83 YDVRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARwQGA 162
Cdd:PRK00077   82 LDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYLGGPNAKVLPVPMMNIINGGAHAD-NNV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 163 DFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIVIC 242
Cdd:PRK00077  161 DIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGEDIALA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 243 MDPASSEFYADGKYTLRTENtqLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTNVK 322
Cdd:PRK00077  241 LDCAASEFYKDGKYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDLFVTNTK 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 323 YIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERIEK 402
Cdd:PRK00077  319 RLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 398

                         410       420
                  ....*....|....*....|....*.
gi 1705116580 403 YNQLMRIEDELGDAAIFAGKTAFKKR 428
Cdd:PRK00077  399 YNQLLRIEEELGDAARYAGKKAFKNL 424
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 7-412 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 694.61  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   7 SIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQGYDVR 86
Cdd:cd03313     1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  87 SQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARWqGADFQE 166
Cdd:cd03313    81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAAYVLPVPMFNVINGGAHAGN-KLDFQE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 167 FMIAPWGASSVREAIRWGSEVYQALRQVLLEKG--LSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIVICMD 244
Cdd:cd03313   160 FMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAIALD 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 245 PASSEFYADGKYTLRT-ENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTNVKY 323
Cdd:cd03313   240 VAASEFYDEGKYVYDSdEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVTNPER 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 324 IQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERIEKY 403
Cdd:cd03313   320 LKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSERTAKY 399


                  ....*....
gi 1705116580 404 NQLMRIEDE 412
Cdd:cd03313   400 NQLLRIEEE 408
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 5-427 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 655.20  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   5 IESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQGYD 84
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  85 VRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGGVHARwQGADF 164
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNAYVLPVPMMNIINGGAHAD-NNLDF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 165 QEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKGLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRPGEDIVICMD 244
Cdd:TIGR01060 160 QEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVALALD 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 245 PASSEFY--ADGKYTLRTENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFVTNVK 322
Cdd:TIGR01060 240 CAASEFYdeEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVTNTE 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 323 YIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGHLKTGAPSRGERIEK 402
Cdd:TIGR01060 320 ILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSERIAK 399

                         410       420
                  ....*....|....*....|....*
gi 1705116580 403 YNQLMRIEDELGDAAIFAGKTAFKK 427
Cdd:TIGR01060 400 YNQLLRIEEELGDSARYAGKNSFYR 424
PTZ00081 PTZ00081
enolase; Provisional
 5-423 0e+00

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 571.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   5 IESIIAREILDSRGNPTVEVEVTSKDGsMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQGYD 84
Cdd:PTZ00081    4 IKSIKAREILDSRGNPTVEVDLTTEKG-VFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALIGKD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  85 VRSQKEIDNCLI-TLDGTEN-----KGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGAN-----LLPVPCMNIING 153
Cdd:PTZ00081   83 VTDQKKLDKLMVeQLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKptdkfVLPVPCFNVING 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 154 GVHARWQGAdFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEK-GLS-TGVGDEGGFAPAVSSNRQPLELIVEAISKA 231
Cdd:PTZ00081  163 GKHAGNKLA-FQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIKKA 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 232 GYRpGEdIVICMDPASSEFYADGK--YTL------RTENTQLSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHA 303
Cdd:PTZ00081  242 GYE-GK-VKICMDVAASEFYDKEKkvYDLdfknpnNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKLTA 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 304 ALGGKVELVGDDIFVTNVKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVG 383
Cdd:PTZ00081  320 AIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLVVG 399

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 1705116580 384 LRAGHLKTGAPSRGERIEKYNQLMRIEDELGDAAIFAGKT 423
Cdd:PTZ00081  400 LGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAGEN 439
PLN00191 PLN00191
enolase
 1-427 0e+00

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 538.14  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   1 MSFEIESIIAREILDSRGNPTVEVEVTSKDGsMARASVPSGASTGSREAIEHRDGDKtRFGGKGVQDAVRSINTEINDAL 80
Cdd:PLN00191   24 VMATITKVKARQIIDSRGNPTVEVDLHTSKG-MFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPAL 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  81 QGYDVRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRY---LGGVGANLLPVPCMNIINGGVHA 157
Cdd:PLN00191  102 IGMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHiadLAGNKKLVLPVPAFNVINGGSHA 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 158 RWQGAdFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEK--GLSTGVGDEGGFAPAVSSNRQPLELIVEAISKAGYRp 235
Cdd:PLN00191  182 GNKLA-MQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT- 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 236 gEDIVICMDPASSEFY-ADGKYTL--RTENTQ----LSAEEMTRYYEQLVNDFPIVLIEDGLAEDDWAGWKILHAalGGK 308
Cdd:PLN00191  260 -GKIKIGMDVAASEFYtKDKKYDLdfKEENNDgsnkKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTS--LED 336

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 309 VELVGDDIFVTNVKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVDSFIADMTVGLRAGH 388
Cdd:PLN00191  337 VQIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQ 416

                         410       420       430
                  ....*....|....*....|....*....|....*....
gi 1705116580 389 LKTGAPSRGERIEKYNQLMRIEDELGDAAIFAGKtAFKK 427
Cdd:PLN00191  417 IKTGAPCRSERLAKYNQLLRIEEELGDEAVYAGE-NFRK 454
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
143-427 1.49e-136

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 393.38  E-value: 1.49e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 143 LPVPCMNIINGGVHARwQGADFQEFMIAPWGASSVREAIRWGSEVYQALRQVLLEKG--LSTGVGDEGGFAPAVSSNRQP 220
Cdd:pfam00113   4 LPVPMMNVINGGSHAG-NNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYgqSATNVGDEGGFAPNLQSNKEA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 221 LELIVEAISKAGYRPgeDIVICMDPASSEFYA--DGKYTLRTENTQ------LSAEEMTRYYEQLVNDFPIVLIEDGLAE 292
Cdd:pfam00113  83 LDLIVEAIEKAGYKG--KIKIAMDVASSEFYNkkDGKYDLDFKGEKsdkskkLTSAQLADLYEELVKKYPIVSIEDPFDE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 293 DDWAGWKILHAALGGKVELVGDDIFVTNVKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGET 372
Cdd:pfam00113 161 DDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGET 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1705116580 373 VDSFIADMTVGLRAGHLKTGAPSRGERIEKYNQLMRIEDELGDAAIFAGKTAFKK 427
Cdd:pfam00113 241 EDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKP 295
Enolase_N pfam03952
Enolase, N-terminal domain;
5-135 1.07e-79

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 241.90  E-value: 1.07e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   5 IESIIAREILDSRGNPTVEVEVTSKDGSMARASVPSGASTGSREAIEHRDGDKTRFGGKGVQDAVRSINTEINDALQGYD 84
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1705116580  85 VRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYL 135
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
PRK08350 PRK08350
hypothetical protein; Provisional
 5-262 5.20e-14

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 72.92  E-value: 5.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   5 IESIIAREILDSRGNPTVEVEVTSKDGsMARASVPSGASTGSREAIEHRdgdktrfggkgvqdAVRSINTEINDALQGYD 84
Cdd:PRK08350    4 IENIIGRVAVLRGGKYSVEVDVITDSG-FGRFAAPIDENPSLYIAEAHR--------------AVSEVDEIIGPELIGFD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  85 VRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGVGANLLPVPCMNIINGgvharwqgaDF 164
Cdd:PRK08350   69 ASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYIGGTFTTELPVPILEFAED---------EN 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 165 QEFMIAPWGASSVREAIRWGSEVYQALRQVLLEkGLSTG---VGDEGGFAPAVS-SNRQPLEL-----IVEAISKAGYRP 235
Cdd:PRK08350  140 FEYYVLVRDLMEITDVVDAVNKILENSKEVSLE-GLSKAsekAGDELGLEVALGiAQKREMETekvlnLVEDNNIAYIKP 218

                         250       260
                  ....*....|....*....|....*....
gi 1705116580 236 --GEDIVICMDPASSEFYADGKYTLRTEN 262
Cdd:PRK08350  219 igDEELFLELIAGTHGVFIDGEYLFRTRN 247
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 216-374 5.35e-12

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 65.04  E-value: 5.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 216 SNRQPLELIVEAIskagyrpGEDIVICMDPASSefyadgkytlrtentqLSAEEMTRYYEQLvNDFPIVLIEDGLAEDDW 295
Cdd:cd00308    79 GSIERVRAVREAF-------GPDARLAVDANGA----------------WTPKEAIRLIRAL-EKYGLAWIEEPCAPDDL 134

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1705116580 296 AGWKILHAALGgkVELVGDDIFVTnVKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQDNNWGTFISHRSGETVD 374
Cdd:cd00308   135 EGYAALRRRTG--IPIAADESVTT-VDDALEALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLESSIG 210
PTZ00378 PTZ00378
hypothetical protein; Provisional
 4-413 1.45e-09

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 59.89  E-value: 1.45e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580   4 EIESIIAREILDSRGNPTVEVEVtskdgsmaRASVPSGASTGSREAIEHRDGDktrfggkGVQDAVRSINTEINDALQ-- 81
Cdd:PTZ00378   50 EIRALVHNEVLSPAGETVLRFTL--------ELLNGMEVSSGALLSPSHGERD-------GEADATLDPAEYTTEALQns 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580  82 --------GYdvRSQKEIDNCLITLDGTENKGRLGANAILGVSLAVSRLAAQLSSTPLYRYLGGV-----GANLLPVPCM 148
Cdd:PTZ00378  115 yfprllqlGA--RDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRALfgsltSVETFSMPQL 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 149 NIINGGVHARwqgADfqefmiAPWGASSVR--EAIRWGS---EVYQALRQV--LLEKGLSTGVGDEGGFAPAVSSN-RQP 220
Cdd:PTZ00378  193 CITFFGPGNP---ST------ARLALKSVLfsPVMPSGTvlrERMQKIFAAfhHFCQSHNSSVRSDGSLHWDGFANlTDA 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 221 LELIVEAISKAGYRPGEDIVICMDPASS------EFYADGK------------YTLRTENTQLSAEEMTRYY-EQL--VN 279
Cdd:PTZ00378  264 VKLATEALRAVQLTPGTDVCLGLRMAASttrvpaTAVADGGawkeakddcevlYSLFPGEPDVTGDQLSEYVrEQLqaVP 343

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1705116580 280 DFpIVLIEDGLAEDDWAGWKILHAALGGKVELVGDDIFV-TNVKYIQRGIDENLANAALIKLNQIGTLSETIEAIQLCQD 358
Cdd:PTZ00378  344 DI-VVYVEDTHCDEDTFGLQRLQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGE 422

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1705116580 359 NNwGTFISHRSGETVD--SFIADMTVGLRAGHLKTGAPSRGERIEKYNQLMRIEDEL 413
Cdd:PTZ00378  423 DE-GRAVTVLVQTLAGnaATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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