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Conserved domains on  [gi|1706365840|ref|WP_142781002|]
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MULTISPECIES: glycosyltransferase family 2 protein [Rhizobium/Agrobacterium group]

Protein Classification

glycosyltransferase family 2 protein( domain architecture ID 11421525)

glycosyltransferase family 2 protein catalyzes the transfer of saccharide moieties from a donor to an acceptor to form glycosidic bonds

CAZY:  GT2
EC:  2.4.-.-
Gene Ontology:  GO:0016757
PubMed:  16037492|18518825

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 8-211 8.59e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 94.00  E-value: 8.59e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   8 ICVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSA 86
Cdd:COG0463     4 VSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVvDDGSTDGTAEILRELAAKDPRIRVIRLERNRGKGAARNAGLAAARG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  87 PLISILDADDFFFRGRFAAMLA---DDDWDLVADNiAFIQQSVPGASSMQPARFEPQARFLSLTEFVEGNIsrpgverge 163
Cdd:COG0463    84 DYIAFLDADDQLDPEKLEELVAaleEGPADLVYGS-RLIREGESDLRRLGSRLFNLVRLLTNLPDSTSGFR--------- 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1706365840 164 tgflkpVIRRAFLdkHALRYDDglRLGEDYELyVRALAAGARYKVIRH 211
Cdd:COG0463   154 ------LFRREVL--EELGFDE--GFLEDTEL-LRALRHGFRIAEVPV 190
 
Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 8-211 8.59e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 94.00  E-value: 8.59e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   8 ICVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSA 86
Cdd:COG0463     4 VSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVvDDGSTDGTAEILRELAAKDPRIRVIRLERNRGKGAARNAGLAAARG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  87 PLISILDADDFFFRGRFAAMLA---DDDWDLVADNiAFIQQSVPGASSMQPARFEPQARFLSLTEFVEGNIsrpgverge 163
Cdd:COG0463    84 DYIAFLDADDQLDPEKLEELVAaleEGPADLVYGS-RLIREGESDLRRLGSRLFNLVRLLTNLPDSTSGFR--------- 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1706365840 164 tgflkpVIRRAFLdkHALRYDDglRLGEDYELyVRALAAGARYKVIRH 211
Cdd:COG0463   154 ------LFRREVL--EELGFDE--GFLEDTEL-LRALRHGFRIAEVPV 190
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 9-175 1.90e-19

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 83.98  E-value: 1.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   9 CVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSAP 87
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVvDDGSTDGTVEIAEEYAKKDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  88 LISILDADDFFFRGRFAAMLAdddwDLVADNIAFIQQSVPGASSMQPARFEPQARFLSLTEFVEGNISRPGVERGETGFL 167
Cdd:pfam00535  81 YIAFLDADDEVPPDWLEKLVE----ALEEDGADVVVGSRYVIFGETGEYRRASRITLSRLPFFLGLRLLGLNLPFLIGGF 156


                  ....*...
gi 1706365840 168 KPVIRRAF 175
Cdd:pfam00535 157 ALYRREAL 164
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 10-117 6.29e-15

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 71.00  E-value: 6.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  10 VIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSAPL 88
Cdd:cd00761     1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVvDDGSTDGTLEILEEYAKKDPRVIRVINEENQGLAAARNAGLKAARGEY 80

                          90       100
                  ....*....|....*....|....*....
gi 1706365840  89 ISILDADDFFFRGRFAAMLADDDWDLVAD 117
Cdd:cd00761    81 ILFLDADDLLLPDWLERLVAELLADPEAD 109
EPS_HpsE NF038302
hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;
40-148 3.51e-05

hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;


Pssm-ID: 439602 [Multi-domain]  Cd Length: 307  Bit Score: 44.78  E-value: 3.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  40 IDDGSTDTTSDVAH---AADDGTGRLRVVrFEVNRGPSAARNHAISISSAPLISILDADDfffrgrfaamLADDDWdlVA 116
Cdd:NF038302   39 VDNNSTDNTAQVVQeyqKNWPSPYPLRYC-FEPQQGAAFARQRAIQEAKGELIGFLDDDN----------LPAPNW--VA 105

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1706365840 117 DNIAFIQQSvP--GASSMQ---------PARFEPQARFLSLTE 148
Cdd:NF038302  106 AAYAFGQEH-PqaGAYGSQihgdfevepPENFERIAPFLAITE 147
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 1-231 3.58e-05

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 45.04  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   1 MVSGSQPICVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEvNRGPSAARNH 79
Cdd:PRK10073    1 MMNSTPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIvNDGSTDNSVEIAKHYAENYPHVRLLHQA-NAGVSVARNT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  80 AISISSAPLISILDADDFFFRG---RFAAMLADDDWDLVADNIAFI-------QQSVP-----------GASSMQPA--- 135
Cdd:PRK10073   80 GLAVATGKYVAFPDADDVVYPTmyeTLMTMALEDDLDVAQCNADWCfrdtgetWQSIPsdrlrstgvlsGPDWLRMAlss 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840 136 RfepqaRFLSLTefvegnisrpgvergetgFLKpVIRRAFLDKHALRYDDGLRlGEDYELYVRALAAGARYKVIRHCGYG 215
Cdd:PRK10073  160 R-----RWTHVV------------------WLG-VYRRDFIVKNNIKFEPGLH-HQDIPWTTEVMFNALRVRYTEQSLYK 214

                         250
                  ....*....|....*.
gi 1706365840 216 AIVRGNSLSGRHRTED 231
Cdd:PRK10073  215 YYLHDTSVSRLPRQGN 230
 
Name Accession Description Interval E-value
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 8-211 8.59e-23

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 94.00  E-value: 8.59e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   8 ICVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSA 86
Cdd:COG0463     4 VSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVvDDGSTDGTAEILRELAAKDPRIRVIRLERNRGKGAARNAGLAAARG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  87 PLISILDADDFFFRGRFAAMLA---DDDWDLVADNiAFIQQSVPGASSMQPARFEPQARFLSLTEFVEGNIsrpgverge 163
Cdd:COG0463    84 DYIAFLDADDQLDPEKLEELVAaleEGPADLVYGS-RLIREGESDLRRLGSRLFNLVRLLTNLPDSTSGFR--------- 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1706365840 164 tgflkpVIRRAFLdkHALRYDDglRLGEDYELyVRALAAGARYKVIRH 211
Cdd:COG0463   154 ------LFRREVL--EELGFDE--GFLEDTEL-LRALRHGFRIAEVPV 190
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 9-175 1.90e-19

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 83.98  E-value: 1.90e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   9 CVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSAP 87
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVvDDGSTDGTVEIAEEYAKKDPRVRVIRLPENRGKAGARNAGLRAATGD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  88 LISILDADDFFFRGRFAAMLAdddwDLVADNIAFIQQSVPGASSMQPARFEPQARFLSLTEFVEGNISRPGVERGETGFL 167
Cdd:pfam00535  81 YIAFLDADDEVPPDWLEKLVE----ALEEDGADVVVGSRYVIFGETGEYRRASRITLSRLPFFLGLRLLGLNLPFLIGGF 156


                  ....*...
gi 1706365840 168 KPVIRRAF 175
Cdd:pfam00535 157 ALYRREAL 164
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 7-121 3.23e-16

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 77.86  E-value: 3.23e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   7 PICVIIAAKNASETIDIAIRSALVEPEVGEVVVI---DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISI 83
Cdd:COG1215    30 RVSVIIPAYNEEAVIEETLRSLLAQDYPKEKLEVivvDDGSTDETAEIARELAAEYPRVRVIERPENGGKAAALNAGLKA 109

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1706365840  84 SSAPLISILDADDFFFRGRFAAM---LADDDWDLVADNIAF 121
Cdd:COG1215   110 ARGDIVVFLDADTVLDPDWLRRLvaaFADPGVGASGANLAF 150
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 10-117 6.29e-15

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 71.00  E-value: 6.29e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  10 VIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSAPL 88
Cdd:cd00761     1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVvDDGSTDGTLEILEEYAKKDPRVIRVINEENQGLAAARNAGLKAARGEY 80

                          90       100
                  ....*....|....*....|....*....
gi 1706365840  89 ISILDADDFFFRGRFAAMLADDDWDLVAD 117
Cdd:cd00761    81 ILFLDADDLLLPDWLERLVAELLADPEAD 109
DPM_DPG-synthase_like cd04179
DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the ...
 10-115 1.71e-10

DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133022 [Multi-domain]  Cd Length: 185  Bit Score: 59.12  E-value: 1.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  10 VIIAAKNASETIDIAIRSALVEPEVGEVVVI---DDGSTDTTSDVAHAADDGTGRLRVVRFEVNRGPSAARNHAISISSA 86
Cdd:cd04179     1 VVIPAYNEEENIPELVERLLAVLEEGYDYEIivvDDGSTDGTAEIARELAARVPRVRVIRLSRNFGKGAAVRAGFKAARG 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1706365840  87 PLISILDAD---DFFFRGRFAAMLADDDWDLV 115
Cdd:cd04179    81 DIVVTMDADlqhPPEDIPKLLEKLLEGGADVV 112
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 10-95 8.02e-10

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 57.24  E-value: 8.02e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  10 VIIAAKNASETIDIAIRSALVEPEVGEV-VVIDDGSTDTTSDVA-HAADDGTGRLRVVRFEVNRGPSAARNHAISISSAP 87
Cdd:cd06423     1 IIVPAYNEEAVIERTIESLLALDYPKLEvIVVDDGSTDDTLEILeELAALYIRRVLVVRDKENGGKAGALNAGLRHAKGD 80


                  ....*...
gi 1706365840  88 LISILDAD 95
Cdd:cd06423    81 IVVVLDAD 88
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
8-108 1.92e-09

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 56.54  E-value: 1.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   8 ICVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGtgRLRVVRFEVNRGPSAARNHAISISSA 86
Cdd:COG1216     5 VSVVIPTYNRPELLRRCLESLLAQTYPPFEVIVvDNGSTDGTAELLAALAFP--RVRVIRNPENLGFAAARNLGLRAAGG 82

                          90       100
                  ....*....|....*....|..
gi 1706365840  87 PLISILDADDFFFRGRFAAMLA 108
Cdd:COG1216    83 DYLLFLDDDTVVEPDWLERLLA 104
GT_2_WfgS_like cd06433
WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella ...
 10-211 1.72e-07

WfgS and WfeV are involved in O-antigen biosynthesis; Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133055 [Multi-domain]  Cd Length: 202  Bit Score: 51.01  E-value: 1.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  10 VIIAAKNASETIDIAIRSALVepevg-evvvIDDGSTDTTSDVAHAADDgtgrlRVVRF--EVNRGPSAARNHAISISSA 86
Cdd:cd06433     2 IITPTYNQAETLEETIDSVLSqtypnieyivIDGGSTDGTVDIIKKYED-----KITYWisEPDKGIYDAMNKGIALATG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  87 PLISILDADDFFFRGRFAAMLAD----DDWDLVADNIAFIQQSVPGassmqpARFEPQARFLSLTEFVEGNISRPGVerg 162
Cdd:cd06433    77 DIIGFLNSDDTLLPGALLAVVAAfaehPEVDVVYGDVLLVDENGRV------IGRRRPPPFLDKFLLYGMPICHQAT--- 147

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1706365840 163 etgflkpVIRRAFLDKHALrYDDGLRLGEDYELYVRALAAGARYKVIRH 211
Cdd:cd06433   148 -------FFRRSLFEKYGG-FDESYRIAADYDLLLRLLLAGKIFKYLPE 188
DPG_synthase cd04188
DPG_synthase is involved in protein N-linked glycosylation; UDP-glucose:dolichyl-phosphate ...
 10-95 1.11e-06

DPG_synthase is involved in protein N-linked glycosylation; UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate.


Pssm-ID: 133031 [Multi-domain]  Cd Length: 211  Bit Score: 48.72  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  10 VIIAAKNASETIDIAIRSALVEPEVGEVVV-----IDDGSTDTTSDVAHA-ADDGTGRLRVVRFEVNRGPSAARNHAISI 83
Cdd:cd04188     1 VVIPAYNEEKRLPPTLEEAVEYLEERPSFSyeiivVDDGSKDGTAEVARKlARKNPALIRVLTLPKNRGKGGAVRAGMLA 80

                          90
                  ....*....|..
gi 1706365840  84 SSAPLISILDAD 95
Cdd:cd04188    81 ARGDYILFADAD 92
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 7-116 2.55e-05

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 44.88  E-value: 2.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   7 PICVIIAAKNASETIDIAIRSALVEPEVGEVVVI---DDGSTDTTSDVAHAADDgtGRLRVVRFEVNRGPSAARNHAISI 83
Cdd:cd06439    30 TVTIIIPAYNEEAVIEAKLENLLALDYPRDRLEIivvSDGSTDGTAEIAREYAD--KGVKLLRFPERRGKAAALNRALAL 107

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1706365840  84 SSAPLISILDADDFFFRG---RFAAMLADDDWDLVA 116
Cdd:cd06439   108 ATGEIVVFTDANALLDPDalrLLVRHFADPSVGAVS 143
EPS_HpsE NF038302
hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;
40-148 3.51e-05

hormogonium polysaccharide biosynthesis glycosyltransferase HpsE;


Pssm-ID: 439602 [Multi-domain]  Cd Length: 307  Bit Score: 44.78  E-value: 3.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  40 IDDGSTDTTSDVAH---AADDGTGRLRVVrFEVNRGPSAARNHAISISSAPLISILDADDfffrgrfaamLADDDWdlVA 116
Cdd:NF038302   39 VDNNSTDNTAQVVQeyqKNWPSPYPLRYC-FEPQQGAAFARQRAIQEAKGELIGFLDDDN----------LPAPNW--VA 105

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1706365840 117 DNIAFIQQSvP--GASSMQ---------PARFEPQARFLSLTE 148
Cdd:NF038302  106 AAYAFGQEH-PqaGAYGSQihgdfevepPENFERIAPFLAITE 147
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 1-231 3.58e-05

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 45.04  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   1 MVSGSQPICVIIAAKNASETIDIAIRSALVEPEVGEVVVI-DDGSTDTTSDVAHAADDGTGRLRVVRFEvNRGPSAARNH 79
Cdd:PRK10073    1 MMNSTPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIvNDGSTDNSVEIAKHYAENYPHVRLLHQA-NAGVSVARNT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  80 AISISSAPLISILDADDFFFRG---RFAAMLADDDWDLVADNIAFI-------QQSVP-----------GASSMQPA--- 135
Cdd:PRK10073   80 GLAVATGKYVAFPDADDVVYPTmyeTLMTMALEDDLDVAQCNADWCfrdtgetWQSIPsdrlrstgvlsGPDWLRMAlss 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840 136 RfepqaRFLSLTefvegnisrpgvergetgFLKpVIRRAFLDKHALRYDDGLRlGEDYELYVRALAAGARYKVIRHCGYG 215
Cdd:PRK10073  160 R-----RWTHVV------------------WLG-VYRRDFIVKNNIKFEPGLH-HQDIPWTTEVMFNALRVRYTEQSLYK 214

                         250
                  ....*....|....*.
gi 1706365840 216 AIVRGNSLSGRHRTED 231
Cdd:PRK10073  215 YYLHDTSVSRLPRQGN 230
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 40-96 1.16e-04

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 42.58  E-value: 1.16e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  40 IDDGSTDT-TSDV--AHAADDGtgRLRVVRFEVNRGPSAARNHAISISSAPLISILDADD 96
Cdd:cd04184    37 ADDASTDPeVKRVlkKYAAQDP--RIKVVFREENGGISAATNSALELATGEFVALLDHDD 94
Beta4Glucosyltransferase cd02511
UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of ...
 7-98 3.48e-04

UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.


Pssm-ID: 133005 [Multi-domain]  Cd Length: 229  Bit Score: 41.51  E-value: 3.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   7 PICVIIAAKNASETIDIAIRSAlvepeVGEVVVI---DDGSTDTTSDVAHAADDgtgrlRVVRFEvNRGPSAARNHAISI 83
Cdd:cd02511     1 TLSVVIITKNEERNIERCLESV-----KWAVDEIivvDSGSTDRTVEIAKEYGA-----KVYQRW-WDGFGAQRNFALEL 69

                          90
                  ....*....|....*
gi 1706365840  84 SSAPLISILDADDFF 98
Cdd:cd02511    70 ATNDWVLSLDADERL 84
GT2_AmsE_like cd04195
GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a ...
 62-205 4.87e-04

GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133038 [Multi-domain]  Cd Length: 201  Bit Score: 40.76  E-value: 4.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  62 LRVVRFEVNRGPSAARNHAISISSAPLISILDADDFFFRGRFA----AMLADDDWDLVADNIA-FIQQSVPGASSMQPar 136
Cdd:cd04195    57 LKVVPLEKNRGLGKALNEGLKHCTYDWVARMDTDDISLPDRFEkqldFIEKNPEIDIVGGGVLeFDSDGNDIGKRRLP-- 134

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1706365840 137 fePQARflSLTEFVegnisrpgveRGETGFLKPVIrrAFLDKHALR---YDDgLRLGEDYELYVRALAAGAR 205
Cdd:cd04195   135 --TSHD--DILKFA----------RRRSPFNHPTV--MFRKSKVLAvggYQD-LPLVEDYALWARMLANGAR 189
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 41-206 1.33e-03

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 39.54  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  41 DDGSTDTTSDVAHA-ADDGTGRLRVVRFEVNRGPsaARN--HAISISSAPLISILDADDFFFRGR----FAAMLADDDWD 113
Cdd:cd04196    34 DDGSTDGTVEIIKEyIDKDPFIIILIRNGKNLGV--ARNfeSLLQAADGDYVFFCDQDDIWLPDKlerlLKAFLKDDKPL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840 114 LVADNIAFIQQ--SVPGASSMQPARFEPQARFLSLteFVEGNIsrpgvergeTGFLKpVIRRAFLDkHALRYDDGLRLGE 191
Cdd:cd04196   112 LVYSDLELVDEngNPIGESFFEYQKIKPGTSFNNL--LFQNVV---------TGCTM-AFNRELLE-LALPFPDADVIMH 178

                         170
                  ....*....|....*
gi 1706365840 192 DYELYVRALAAGARY 206
Cdd:cd04196   179 DWWLALLASAFGKVV 193
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 8-205 2.35e-03

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 38.75  E-value: 2.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840   8 ICVIIAAKNASETIDIAIRSALVEPEVGEVVVI---DDGSTDTTSDVAHaadDGTGRLRVVRFEVN--RGPSAARNHAIS 82
Cdd:cd02525     2 VSIIIPVRNEEKYIEELLESLLNQSYPKDLIEIivvDGGSTDGTREIVQ---EYAAKDPRIRLIDNpkRIQSAGLNIGIR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1706365840  83 ISSAPLISILDA----DDFFFRGRFAAMLADDdwdlvADNIAFIQQSVPGASsmqparFEPQARFLSLTEFVEGNISRPG 158
Cdd:cd02525    79 NSRGDIIIRVDAhavyPKDYILELVEALKRTG-----ADNVGGPMETIGESK------FQKAIAVAQSSPLGSGGSAYRG 147

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1706365840 159 VeRGETGFLKPV----IRRAFLDKHALrYDDGLRLGEDYELYVRALAAGAR 205
Cdd:cd02525   148 G-AVKIGYVDTVhhgaYRREVFEKVGG-FDESLVRNEDAELNYRLRKAGYK 196
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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