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Conserved domains on  [gi|1717126514|ref|WP_144317717|]
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1-acyl-sn-glycerol-3-phosphate acyltransferase [Corynebacterium sanguinis]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 11415180)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid; 1-acyl-sn-glycerol-3-phosphate acyltransferase, for example, converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position by utilizing either acyl-CoA or acyl-ACP as the fatty acyl donor;

CATH:  1.10.1200.50
EC:  2.3.1.-
Gene Ontology:  GO:0008654|GO:0016746
PubMed:  18718904|18931347
SCOP:  4003349

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 25-231 1.33e-56

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


:

Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 180.98  E-value: 1.33e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  25 RDPFYHNVIRVIKTVFRAQGTVAVSHGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGA 104
Cdd:COG0204     9 RRFRYRLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLA----ALPRPVRFVAKKELFKIPLLGW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 105 MMRGMRHVPVDR---AAGADSIDSAVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRIWT 181
Cdd:COG0204    85 LLRALGAIPVDRskrRAALRALRQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALP 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1717126514 182 KELPRRLGRthtpVIIRYGAPVSLEGTP----EEVTARLKLAVQELLDANRAEY 231
Cdd:COG0204   165 KGFLPRPGK----VTVRIGPPIDPSDLEgedrRELAERLRAAIEALLAELRAEA 214
 
Name Accession Description Interval E-value
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 25-231 1.33e-56

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 180.98  E-value: 1.33e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  25 RDPFYHNVIRVIKTVFRAQGTVAVSHGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGA 104
Cdd:COG0204     9 RRFRYRLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLA----ALPRPVRFVAKKELFKIPLLGW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 105 MMRGMRHVPVDR---AAGADSIDSAVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRIWT 181
Cdd:COG0204    85 LLRALGAIPVDRskrRAALRALRQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALP 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1717126514 182 KELPRRLGRthtpVIIRYGAPVSLEGTP----EEVTARLKLAVQELLDANRAEY 231
Cdd:COG0204   165 KGFLPRPGK----VTVRIGPPIDPSDLEgedrRELAERLRAAIEALLAELRAEA 214
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 50-219 1.96e-48

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 158.97  E-value: 1.96e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDSA 126
Cdd:cd07989    15 EGLENLPPKGPVIIVANHQSYLDPLVLGA----ALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRgngRSAREALREA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 127 VDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRIWTKELPRRLGRThtpVIIRYGAPVSLE 206
Cdd:cd07989    91 IEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR---VTVRIGEPIPPE 167

                         170
                  ....*....|...
gi 1717126514 207 GTPEEVTARLKLA 219
Cdd:cd07989   168 GLELAEEDRKELR 180
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 50-174 9.71e-37

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 127.39  E-value: 9.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIPAEGGALIAANHTGWLDFIF-TGMGPHiaGRRLVRFMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDS 125
Cdd:pfam01553   5 HGLENLPRGGPAIVVANHQSYLDVLLlSLALYK--RGRPLVFVAKKELFDIPLVGWLMRLLGCIFIDRknrKDAAGTLEY 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1717126514 126 AVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIW 174
Cdd:pfam01553  83 LVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 61-176 3.31e-33

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 117.84  E-value: 3.31e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514   61 ALIAANHTGWLDFIFTGMGPHIAGRRlVRFMAKKEVFSAPVIGAMMRGMRHVPVDRAAGA---DSIDSAVDWIKKGSLVG 137
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKLGR-VRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRkarAALREAVELLKEGEWLL 79

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1717126514  138 IFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGS 176
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIRGT 118
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 50-223 9.06e-29

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 115.41  E-value: 9.06e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514   50 HGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGAMMRGMRHVPVDRAAGADSIDSAVDW 129
Cdd:PRK08633   432 EGRENIPAKGGALLLGNHVSWIDWALLQA----ASPRPIRFVMERSIYEKWYLKWFFKLFGVIPISSGGSKESLEFIRKA 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  130 IKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAI---WGSQ--RIWTKELPRRLGRTHTPVIIRYGAPVS 204
Cdd:PRK08633   508 LDDGEVVCIFPEGAITRNGQLNEFKRGFELIVKGTDVPIIPFYIrglWGSIfsRASGKFLWRWPTRIPYPVTVAFGKPMP 587

                          170
                   ....*....|....*....
gi 1717126514  205 LEGTPEEVtarlKLAVQEL 223
Cdd:PRK08633   588 AHSTAHEV----KQAVFEL 602
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 51-173 2.95e-27

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 102.42  E-value: 2.95e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  51 GLEHIPAEGGALIAANHTGWLDFIFTG--MGPHIAgrrlvrFMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDS 125
Cdd:TIGR00530   8 GPENLPAKSPVLVVANHQSNLDPLTLSaaFPPPIV------FIAKKELKWIPFFGIMLWLTGAIFIDReniRAIATALKA 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1717126514 126 AVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAI 173
Cdd:TIGR00530  82 AIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVL 129
 
Name Accession Description Interval E-value
PlsC COG0204
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ...
 25-231 1.33e-56

1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 439974 [Multi-domain]  Cd Length: 215  Bit Score: 180.98  E-value: 1.33e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  25 RDPFYHNVIRVIKTVFRAQGTVAVSHGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGA 104
Cdd:COG0204     9 RRFRYRLVRLWARLLLRLLGVRVRVEGLENLPADGPVLIVANHQSWLDILLLLA----ALPRPVRFVAKKELFKIPLLGW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 105 MMRGMRHVPVDR---AAGADSIDSAVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRIWT 181
Cdd:COG0204    85 LLRALGAIPVDRskrRAALRALRQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEAGVPIVPVAIDGTERALP 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1717126514 182 KELPRRLGRthtpVIIRYGAPVSLEGTP----EEVTARLKLAVQELLDANRAEY 231
Cdd:COG0204   165 KGFLPRPGK----VTVRIGPPIDPSDLEgedrRELAERLRAAIEALLAELRAEA 214
LPLAT_AGPAT-like cd07989
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ...
 50-219 1.96e-48

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.


Pssm-ID: 153251 [Multi-domain]  Cd Length: 184  Bit Score: 158.97  E-value: 1.96e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDSA 126
Cdd:cd07989    15 EGLENLPPKGPVIIVANHQSYLDPLVLGA----ALPRPIRFVAKKELFKIPFLGWLLRLLGAIPIDRgngRSAREALREA 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 127 VDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRIWTKELPRRLGRThtpVIIRYGAPVSLE 206
Cdd:cd07989    91 IEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEAGVPIVPVAISGTWGSLPKGKKLPRPGR---VTVRIGEPIPPE 167

                         170
                  ....*....|...
gi 1717126514 207 GTPEEVTARLKLA 219
Cdd:cd07989   168 GLELAEEDRKELR 180
Acyltransferase pfam01553
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ...
 50-174 9.71e-37

Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.


Pssm-ID: 366704 [Multi-domain]  Cd Length: 131  Bit Score: 127.39  E-value: 9.71e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIPAEGGALIAANHTGWLDFIF-TGMGPHiaGRRLVRFMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDS 125
Cdd:pfam01553   5 HGLENLPRGGPAIVVANHQSYLDVLLlSLALYK--RGRPLVFVAKKELFDIPLVGWLMRLLGCIFIDRknrKDAAGTLEY 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1717126514 126 AVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIW 174
Cdd:pfam01553  83 LVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEAGVPIVPVAIS 131
PlsC smart00563
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ...
 61-176 3.31e-33

Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.


Pssm-ID: 214724 [Multi-domain]  Cd Length: 118  Bit Score: 117.84  E-value: 3.31e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514   61 ALIAANHTGWLDFIFTGMGPHIAGRRlVRFMAKKEVFSAPVIGAMMRGMRHVPVDRAAGA---DSIDSAVDWIKKGSLVG 137
Cdd:smart00563   1 ALVVANHQSFLDPLVLSALLPRKLGR-VRFVAKKELFYVPLLGWLLRLLGAIFIDRSNGRkarAALREAVELLKEGEWLL 79

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1717126514  138 IFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGS 176
Cdd:smart00563  80 IFPEGTRSRPGKLLPFKKGAARLALEAGVPIVPVAIRGT 118
PRK08633 PRK08633
2-acyl-glycerophospho-ethanolamine acyltransferase; Validated
 50-223 9.06e-29

2-acyl-glycerophospho-ethanolamine acyltransferase; Validated


Pssm-ID: 236315 [Multi-domain]  Cd Length: 1146  Bit Score: 115.41  E-value: 9.06e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514   50 HGLEHIPAEGGALIAANHTGWLDFIFTGMgphiAGRRLVRFMAKKEVFSAPVIGAMMRGMRHVPVDRAAGADSIDSAVDW 129
Cdd:PRK08633   432 EGRENIPAKGGALLLGNHVSWIDWALLQA----ASPRPIRFVMERSIYEKWYLKWFFKLFGVIPISSGGSKESLEFIRKA 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  130 IKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAI---WGSQ--RIWTKELPRRLGRTHTPVIIRYGAPVS 204
Cdd:PRK08633   508 LDDGEVVCIFPEGAITRNGQLNEFKRGFELIVKGTDVPIIPFYIrglWGSIfsRASGKFLWRWPTRIPYPVTVAFGKPMP 587

                          170
                   ....*....|....*....
gi 1717126514  205 LEGTPEEVtarlKLAVQEL 223
Cdd:PRK08633   588 AHSTAHEV----KQAVFEL 602
AGP_acyltrn TIGR00530
1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous ...
 51-173 2.95e-27

1-acyl-sn-glycerol-3-phosphate acyltransferases; This model describes the core homologous region of a collection of related proteins, several of which are known to act as 1-acyl-sn-glycerol-3-phosphate acyltransferases (EC 2.3.1.51). Proteins scoring above the trusted cutoff are likely to have the same general activity. However, there is variation among characterized members as to whether the acyl group can be donated by acyl carrier protein or coenzyme A, and in the length and saturation of the donated acyl group. 1-acyl-sn-glycerol-3-phosphate acyltransferase is also called 1-AGP acyltransferase, lysophosphatidic acid acyltransferase, and LPA acyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 129621 [Multi-domain]  Cd Length: 130  Bit Score: 102.42  E-value: 2.95e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  51 GLEHIPAEGGALIAANHTGWLDFIFTG--MGPHIAgrrlvrFMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDS 125
Cdd:TIGR00530   8 GPENLPAKSPVLVVANHQSNLDPLTLSaaFPPPIV------FIAKKELKWIPFFGIMLWLTGAIFIDReniRAIATALKA 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1717126514 126 AVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAI 173
Cdd:TIGR00530  82 AIEVLKQGRSIGVFPEGTRSRGRDILPFKKGAFHIAIKAGVPILPVVL 129
LPLAT_ABO13168-like cd07988
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 52-179 3.14e-18

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.


Pssm-ID: 153250 [Multi-domain]  Cd Length: 163  Bit Score: 79.57  E-value: 3.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  52 LEHIPAEGGA--LIAANHTGWLDFIFtGMGPHIAGRRLVRFMAKKEVFSAPViGAMMRGMRHVPVDRAAGADSIDSAVDW 129
Cdd:cd07988    12 IEGEPPNKPKfvVIGAPHTSNWDFVL-GLLAAFALGLKISFLGKHSLFKPPL-GPFMRWLGGIPVDRSRAGGLVEQVVEE 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1717126514 130 IKKGS--LVGIFPEGTISRAfelSDFKTGAARIAQRADAPLIPCAI-WGSQRI 179
Cdd:cd07988    90 FRRREefVLAIAPEGTRSKV---DKWKTGFYHIARGAGVPILLVYLdYKRKTV 139
LPLAT_ACT14924-like cd07986
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 50-220 1.61e-17

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Pectobacterium carotovorum subsp. carotovorum PC1 locus ACT14924 putative acyltransferase, and similar proteins.


Pssm-ID: 153248 [Multi-domain]  Cd Length: 210  Bit Score: 78.83  E-value: 1.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIPAEGGALIAANH-TGWLDFIFTGmgpHIAG--RRLVRFMAKKEVFSAPvigAMMRGMrhVPVD-------RAAG 119
Cdd:cd07986    13 SGLENIPKDGPVVIVANHpFGILDGLILA---DLLGsvRPDVRILANQLLSKIP---ELRDLF--IPVDplegraaLAKN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 120 ADSIDSAVDWIKKGSLVGIFPEGTISRAFEL------SDFKTGAARIAQRADAPLIPCAIWG------------SQRIWT 181
Cdd:cd07986    85 RESLREALRHLKNGGALIIFPAGRVSTASPPfgrvsdRPWNPFVARLARKAKAPVVPVYFSGrnsrlfylagliHPTLRT 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1717126514 182 KELPRRLGR-THTPVIIRYGAPVSLE-----GTPEEVTARLKLAV 220
Cdd:cd07986   165 LLLPRELLNkRGKTIRIRVGRPIPPEelarfEDAEELADFLRLHT 209
PLN02901 PLN02901
1-acyl-sn-glycerol-3-phosphate acyltransferase
 51-179 2.04e-17

1-acyl-sn-glycerol-3-phosphate acyltransferase


Pssm-ID: 215488 [Multi-domain]  Cd Length: 214  Bit Score: 78.62  E-value: 2.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  51 GLEHIPA-EGGALIAANHTGWLDfIFTGMgpHIagRRLVRFMAKKEVFSAPVIGAMMRGMRHVPV---DRAAGADSIDSA 126
Cdd:PLN02901   41 GLENLPSpDEPAVYVSNHQSFLD-IYTLF--HL--GRPFKFISKTSIFLIPIIGWAMYMTGHIPLkrmDRRSQLECLKRC 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1717126514 127 VDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRI 179
Cdd:PLN02901  116 MELLKKGASVFFFPEGTRSKDGKLAAFKKGAFSVAAKTGVPVVPITLVGTGKI 168
LPLAT_MGAT-like cd07987
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; ...
 36-229 2.41e-17

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.


Pssm-ID: 153249 [Multi-domain]  Cd Length: 212  Bit Score: 78.48  E-value: 2.41e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  36 IKTVFRaqgtVAVSHGLEHIPAEGGALIAANHTGWL-DFIFTGMGPHIAGR-RLVRFMAKKEVFSAPVIGAMMRGMRHVP 113
Cdd:cd07987     1 HRKYFR----VYEVRGLENIPDEGPALLVHPHGGLPiDGALLAAAFLLLFPgRLPRALADHFLFPLPGLRDLLRRLGAVP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 114 VDRaagadsiDSAVDWIKKGSLVGIFPEGtISRAFELSD--------FKTGAARIAQRADAPLIPCAIWGSQRIWT---- 181
Cdd:cd07987    77 GSR-------ENCVRLLREGELVLIFPGG-AREALKSKReeyyllwkKRKGFARLALRAGAPIVPVFTFGEEELFRvlgd 148

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1717126514 182 ------KELPRRLG-RTHTPVIIRYGAPVSLEGT---------PEEVTARLKLAVQELLDANRA 229
Cdd:cd07987   149 pdgpvgKRLFRLLPlPRRLPLYPVFGEPIVVPRPpipdppdedVEELHQKYIAALRELIEKHKK 212
LPLAT cd06551
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 50-225 2.88e-15

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


Pssm-ID: 153244 [Multi-domain]  Cd Length: 187  Bit Score: 72.06  E-value: 2.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIPAEGGALIAANHTGWLDFiftgmgphiagrrLVRFMAKKEVFSAPVIGAMMR-GMRHVPVDRAAGADSIDS--- 125
Cdd:cd06551    17 KGPPPPPGGGPVLFVSNHSSWWDG-------------LILFLLLERGLRRDVYGLMDEeLLERYPFFTRLGAFSVDRdsp 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 126 ---------AVDWIKK-GSLVGIFPEGTISRAFE-LSDFKTGAARIAQRADAPLIPCAIWGsqriwTKELPRRLGrthtP 194
Cdd:cd06551    84 rsaakslkyVARLLSKpGSVVWIFPEGTRTRRDKrPLQFKPGVAHLAEKAGVPIVPVALRY-----TFELFEQFP----E 154

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1717126514 195 VIIRYGAPVSLEGT--PEEVTARLKLAVQELLD 225
Cdd:cd06551   155 IFVRIGPPIPYAETalGEELAAELANRLTRLLD 187
LPLAT_AAK14816-like cd07992
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ...
 34-232 2.25e-14

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.


Pssm-ID: 153254 [Multi-domain]  Cd Length: 203  Bit Score: 69.98  E-value: 2.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  34 RVIKTVFRaqgTVAVShGLEHIPAEGGALIAANHTGWLDFIFTGMGPHiagRRLVRFMAKKEVFSAPVIGAMMRGMRHVP 113
Cdd:cd07992     7 VILRIYFR---RITVV-GRENVPKDGPVIFLGNHPNALIDPLLLAATL---RRPVRFLAKADLFKNPLIGWLLESFGAIP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 114 VDRA-----AGADSIDSA------VDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRA------DAPLIPCAIWGS 176
Cdd:cd07992    80 VYRPkdlarGGIGKISNAavfdavGEALKAGGAIGIFPEGGSHDRPRLLPLKAGAARMALEAleagqkDVKIVPVGLNYE 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717126514 177 QriwtKELPRRlgrthtPVIIRYGAPVSLEGTPEEVTARlkLAVQELLDANRAEYE 232
Cdd:cd07992   160 D----KSRFRS------RVLVEFGKPISVSAFEEAEASR--DVEKKLINQLEAELE 203
PRK06814 PRK06814
acyl-[ACP]--phospholipid O-acyltransferase;
34-210 3.18e-13

acyl-[ACP]--phospholipid O-acyltransferase;


Pssm-ID: 235865 [Multi-domain]  Cd Length: 1140  Bit Score: 69.61  E-value: 3.18e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514   34 RVIKTVFRAQGTVAVsHGLEHIPAEGG-ALIAANHTGWLDfiftgmGPHIAG--RRLVRFMAKKEVFSAPVIGAMMRGMR 110
Cdd:PRK06814   429 DIFSILFRAFYRVEV-KGLENLQKAGKkAVIAANHVSFLD------GPLLAAylPEEPTFAIDTDIAKAWWVKPFLKLAK 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  111 HVPVDrAAGADSIDSAVDWIKKGSLVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQRIWTKELPRRLGR 190
Cdd:PRK06814   502 ALPVD-PTNPMATRTLIKEVQKGEKLVIFPEGRITVTGSLMKIYDGPGMIADKAGAMVVPVRIDGLQFTHFSRLKNQVRR 580

                          170       180
                   ....*....|....*....|.
gi 1717126514  191 THTP-VIIRYGAPVSLEGTPE 210
Cdd:PRK06814   581 KWFPkVTVTILPPVKLAVDPE 601
LPLAT_LPCAT1-like cd07991
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; ...
 36-157 8.03e-12

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.


Pssm-ID: 153253 [Multi-domain]  Cd Length: 211  Bit Score: 63.01  E-value: 8.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  36 IKTVFRAQGTVAVS-HGLEHiPAEGGALIAANHTGWLD-FIFTGMGPHIagrrlvrFMAKKEVFSAPVIGAMMRGMRHVP 113
Cdd:cd07991     1 ARVLLFAFGFYVIKvHGKPD-PPEAPRIIVANHTSFIDpLILFSDLFPS-------IVAKKELGKLPFIGTILRALGCIF 72

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1717126514 114 VDR------AAGADSIDSAVDWIKKGSLVgIFPEGTISRAFELSDFKTGA 157
Cdd:cd07991    73 VDRsepkdrKKVVEEIKERATDPNWPPIL-IFPEGTTTNGKALIMFKKGA 121
LPLAT_LCLAT1-like cd07990
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; ...
 48-143 3.64e-10

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as Lysocardiolipin acyltransferase 1 (LCLAT1) or 1-acyl-sn-glycerol-3-phosphate acyltransferase and similar proteins.


Pssm-ID: 153252 [Multi-domain]  Cd Length: 193  Bit Score: 58.02  E-value: 3.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  48 VSHGLEHIPAEGGALIAANHTGWLDFIF-------TGMGPHIagrrlvRFMAKKEVFSAPVIGAMMRGMRHVPVDRAAGA 120
Cdd:cd07990    13 VVYGDEPKLPKERALIISNHRSEVDWLVlwmladrFGRLGRL------KIVLKDSLKYPPLGGWGWQLGEFIFLKRKWEK 86

                          90       100
                  ....*....|....*....|....*....
gi 1717126514 121 D--SIDSAVDWIKK----GSLVgIFPEGT 143
Cdd:cd07990    87 DekTIKRQLKRLKDspepFWLL-IFPEGT 114
COG3176 COG3176
Putative hemolysin [General function prediction only];
39-223 2.59e-09

Putative hemolysin [General function prediction only];


Pssm-ID: 442409  Cd Length: 270  Bit Score: 56.59  E-value: 2.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  39 VFRAQG-TVAVSHG-LEHIPAEGGALIAANH-TGWLDFIftgMGPHIAG--RRLVRFMAK------KEVFSAPVIgammr 107
Cdd:COG3176    49 VFEELGaRLEVPEGdLDRIDADGHLLVVANHpLGILDGL---ALLKLVGtvRPDYRILANdlalriPGGFYSELE----- 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 108 gmrhVPVDRAAgADSIDSAVDWIKKGSLVGIFPEGTISRAFELSD--FKTGAARIAQRADAPLIPCAIWG---------- 175
Cdd:COG3176   121 ----FPVDPFN-LETLKAARRHLLEGGRSCVFPAGRVSGARRVIDllWSGLAAKLARKAGAPVVPVYFDGrnsglfylfg 195

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717126514 176 --SQRIWTKELPRR-LGRTHTPVIIRYGAP-----VSLEGTPEEVTARLKLAVQEL 223
Cdd:COG3176   196 siHPTLRTAALPRElLRKRGHLIELRVGRPippleLDLDLDPAELPPLLRGYTYAL 251
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 50-231 2.40e-04

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 41.05  E-value: 2.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  50 HGLEHIP---AEG-GALIAANHTGWLDFIFTGMGphIAGRRLVrFMAKKevFSAPVIGAMMRGMR----HVPVDRAAGAD 121
Cdd:cd07984     7 EGLEHLEaalAKGkGVILLTAHFGNWELAGLALA--LLGYPVT-VVYRP--LKNPLLDRLITRGRerfgARLIPRGGGLR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 122 SIdsaVDWIKKGSLVGIFP------EGTISRAF--ELSDFKTGAARIAQRADAPLIPCAIwgsqriwtkelpRRLGRTHT 193
Cdd:cd07984    82 EL---IRALKKGEIVGILPdqdpgrKGGVFVPFfgRPAATPTGPARLALKTGAPVVPAFA------------YRLPGGGY 146

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1717126514 194 PVIIRYGAPVSLEGTPEEVTARLKLAVQELLDANRAEY 231
Cdd:cd07984   147 RIEFEPPLENPPSEDVEEDTQRLNDALEAAIREHPEQW 184
LPLAT_DUF374-like cd07983
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; ...
 126-226 6.01e-04

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are the uncharacterized DUF374 phospholipid/glycerol acyltransferases and similar proteins.


Pssm-ID: 153245 [Multi-domain]  Cd Length: 189  Bit Score: 39.89  E-value: 6.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 126 AVDWIKKGSLVGIFPE---GTISRAfelsdfKTGAARIAQRADAPLIPCAIWGSQRI----WTK-ELPRRLGRthtpVII 197
Cdd:cd07983    90 MLRALKDGYNIAITPDgprGPRYKV------KPGVILLARKSGAPIVPVAIAASRAWrlksWDRfIIPKPFSR----VVI 159

                          90       100
                  ....*....|....*....|....*....
gi 1717126514 198 RYGAPVSLEgtPEEVTARLKLAVQELLDA 226
Cdd:cd07983   160 VFGEPIHVP--PDADEEELEEYRLELEAA 186
PRK15018 PRK15018
1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional
 59-234 7.24e-04

1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional


Pssm-ID: 184979  Cd Length: 245  Bit Score: 40.00  E-value: 7.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  59 GGALIAANHTGWLDFIftgMGPHIAGRRLVRfMAKKEVFSAPVIGAMMRGMRHVPVDR---AAGADSIDSAVDWIKKGSL 135
Cdd:PRK15018   65 GNAIYIANHQNNYDMV---TASNIVQPPTVT-VGKKSLLWIPFFGQLYWLTGNLLIDRnnrTKAHGTIAEVVNHFKKRRI 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 136 -VGIFPEGTISRAFELSDFKTGAARIAQRADAPLIP-CAIWGSQRIwtkelprRLGRTHTPVIIRYGAPvslegtPEEVT 213
Cdd:PRK15018  141 sIWMFPEGTRSRGRGLLPFKTGAFHAAIAAGVPIIPvCVSTTSNKI-------NLNRLHNGLVIVEMLP------PIDVS 207

                         170       180
                  ....*....|....*....|.
gi 1717126514 214 ARLKLAVQELLDANRAEYEEK 234
Cdd:PRK15018  208 QYGKDQVRELAAHCRSIMEQK 228
PRK08043 PRK08043
bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase;
62-177 8.47e-04

bifunctional acyl-ACP--phospholipid O-acyltransferase/long-chain-fatty-acid--ACP ligase;


Pssm-ID: 181207 [Multi-domain]  Cd Length: 718  Bit Score: 40.85  E-value: 8.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  62 LIAANHTGWLDfiftgmgphiaGRRLVRFMAKKEVF---SAPVIGAMMRGMR----HVPVDrAAGADSIDSAVDWIKKGS 134
Cdd:PRK08043   31 LITPNHVSFLD-----------GILLALFLPVRPVFavyTSISQQWYMRWLKpyidFVPLD-PTKPMAIKHLVRLVEQGR 98

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1717126514 135 LVGIFPEGTISRAFELSDFKTGAARIAQRADAPLIPCAIWGSQ 177
Cdd:PRK08043   99 PVVIFPEGRITVTGSLMKIYDGAGFVAAKSGATVIPVRIEGAE 141
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
18-231 2.06e-03

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 38.87  E-value: 2.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  18 PVHEEAKRDPF----YHNVIRVIKTVFRAQgTVAVSH--------GLEHI----PAEGGALIAANHTGWLDFIFTGMGPH 81
Cdd:pfam03279  64 PEMSEAEREQIidksFASVGRAIVETGRVW-FWPDSRiakrfeviGLEHIkealAQGRGAILVGPHFGNWDLGGRVLGQQ 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  82 IAGRRLVRFMAKKEVFSAPVIGAMMR-GMRHVPVDraagaDSIDSAVDWIKKGSLVGIFPEGTISRAFELS-DF------ 153
Cdd:pfam03279 143 YPGMAVYRPNLKNPLLDWLQTSGRERfGGRMLPRQ-----NGIKGLIKALRKGEVVWYLPDQDLGRKDSVFvPFfgvpaa 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 154 -KTGAARIAQRADAPLIPCAIWgsqriwtkelprRLGRTHTPVIIRYgAPV--SLEGTPEEVTARLKLAVQELLDANRAE 230
Cdd:pfam03279 218 tTTGPAKLALKTKAAVIPVFPI------------RNGDGSGYTVIVH-PALdlTITDDVEQIAQAMNQIVEKFIMPAPEQ 284


                  .
gi 1717126514 231 Y 231
Cdd:pfam03279 285 Y 285
PTZ00261 PTZ00261
acyltransferase; Provisional
 53-234 2.63e-03

acyltransferase; Provisional


Pssm-ID: 240337  Cd Length: 355  Bit Score: 38.72  E-value: 2.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514  53 EHIPAEGGALIAaNHTGWLD-FIFTGMGPHiagRRLV--RFMAKKEVFSAPVIGAMMRGMRHVPVDRAAGADS------- 122
Cdd:PTZ00261  124 DDISRHGCAYVG-NHTSFWDvYAFIGLTPF---RHLLntRTLMKSSLRKIPIFGGVFDRVGHFPVHFKSDSDGnfevdke 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717126514 123 ----IDSAVDW-IKKGSLVGIFPEGTISRAFE-LSDFKTG--AARIAQRADAPLIPCAiwGSQRIWtkelPRR--LGRTH 192
Cdd:PTZ00261  200 kqaqVQQAIDAhLRLGGSLAFFPEGAINKHPQvLQTFRYGtfATIIKHRMEVYYMVSV--GSEKTW----PWWmmIGGLP 273

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1717126514 193 TPVIIRYGA-PVSLEG-TPEEVTARLKLAVQELLDANRAEYEEK 234
Cdd:PTZ00261  274 ADMHIRIGAyPIDYDRdSSKDVAVGLQQRMQKVRDEIAAEVAAA 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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