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Conserved domains on  [gi|1717219873|ref|WP_144398601|]
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type IV pilus twitching motility protein PilT [Criibacterium bergeronii]

Protein Classification

type IV pilus twitching motility protein PilT( domain architecture ID 10006640)

type IV pilus twitching motility protein PilT is a hexameric ATPase that drives pilus retraction, which provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility

CATH:  3.30.450.90
Gene Ontology:  GO:0005524|GO:0043107
PubMed:  12142488
SCOP:  4004005

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
 1-342 0e+00

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


:

Pssm-ID: 442056  Cd Length: 342  Bit Score: 534.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   1 MITLDELLELSVKKNASDIFISVGIKPSLKINGEIYSIYDEIIKPIDSETLVREMykLNPEKFLKFKEKGEDDFSISRAG 80
Cdd:COG2805     2 AMDLDELLKLAVEQGASDLHLTVGSPPMLRIDGELVPLDDPPLTPEDLEALLKEI--LTEEQRERLEEEGELDFSYSLPG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  81 VGRFRVSTYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILT 160
Cdd:COG2805    80 LGRFRVNIFRQRGGVAAVLRLIPSEIPTLEELGLPPVLKELAELPRGLVLVTGPTGSGKSTTLAAMIDYINETRAKHIIT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 161 LEDPIEYLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTV 240
Cdd:COG2805   160 IEDPIEFVHKHKKSLINQREVGRDTPSFANALRAALREDPDVILVGEMRDLETIEAALTAAETGHLVFATLHTNSAAQTI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 241 DRIIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISM 319
Cdd:COG2805   240 DRIIDVFPPEEQAQIRSQLAESLRGVISQRLLPRADGGgRVAAREILVNTPAVRNLIREGKTHQIPSLIQTGKKLGMQTM 319

                         330       340
                  ....*....|....*....|...
gi 1717219873 320 DKYISNLYNYGTITRETAIKYAS 342
Cdd:COG2805   320 DQSLAELVKEGLITEETALAYAS 342
 
Name Accession Description Interval E-value
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
 1-342 0e+00

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


Pssm-ID: 442056  Cd Length: 342  Bit Score: 534.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   1 MITLDELLELSVKKNASDIFISVGIKPSLKINGEIYSIYDEIIKPIDSETLVREMykLNPEKFLKFKEKGEDDFSISRAG 80
Cdd:COG2805     2 AMDLDELLKLAVEQGASDLHLTVGSPPMLRIDGELVPLDDPPLTPEDLEALLKEI--LTEEQRERLEEEGELDFSYSLPG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  81 VGRFRVSTYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILT 160
Cdd:COG2805    80 LGRFRVNIFRQRGGVAAVLRLIPSEIPTLEELGLPPVLKELAELPRGLVLVTGPTGSGKSTTLAAMIDYINETRAKHIIT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 161 LEDPIEYLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTV 240
Cdd:COG2805   160 IEDPIEFVHKHKKSLINQREVGRDTPSFANALRAALREDPDVILVGEMRDLETIEAALTAAETGHLVFATLHTNSAAQTI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 241 DRIIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISM 319
Cdd:COG2805   240 DRIIDVFPPEEQAQIRSQLAESLRGVISQRLLPRADGGgRVAAREILVNTPAVRNLIREGKTHQIPSLIQTGKKLGMQTM 319

                         330       340
                  ....*....|....*....|...
gi 1717219873 320 DKYISNLYNYGTITRETAIKYAS 342
Cdd:COG2805   320 DQSLAELVKEGLITEETALAYAS 342
pilT_fam TIGR01420
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ...
 3-345 1.30e-154

pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]


Pssm-ID: 273613  Cd Length: 343  Bit Score: 437.91  E-value: 1.30e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   3 TLDELLELSVKKNASDIFISVGIKPSLKINGEIYSIYDEIIKPIDSETLVREMykLNPEKFLKFKEKGEDDFSISRAGVG 82
Cdd:TIGR01420   1 SLEEILREAVKLGASDIHLTAGAPPAMRIDGDLVRIEFEPLTPEDTQKLAREI--LSEKQREEFEENGELDFSFSLPGVG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  83 RFRVSTYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILTLE 162
Cdd:TIGR01420  79 RFRVNAFYQRGGVALVLRLIPSKIPTFEELGLPPVLRELAERPRGLILVTGPTGSGKSTTLASMIDYINKNKAYHIITIE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 163 DPIEYLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDR 242
Cdd:TIGR01420 159 DPIEYVHTNKRSLINQREVGEDTLSFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTLHTNSAAQTIER 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 243 IIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISMDK 321
Cdd:TIGR01420 239 IIDVFPAEEQEQIRTQLAESLVAIISQRLLPKADGGgRVLAVEILINTPAVRNLIREGKTHQIKSLIQTGQQLGMQTFDQ 318

                         330       340
                  ....*....|....*....|....
gi 1717219873 322 YISNLYNYGTITRETAIKYASNAE 345
Cdd:TIGR01420 319 HLAQLYKKGLITLEDALEAAPSPH 342
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
 107-327 2.19e-128

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 366.48  E-value: 2.19e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 107 LDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILTLEDPIEYLFKHDKAIVDQREIGIDTK 186
Cdd:cd01131     2 PTFEELGLPPVLKDLALKPRGLVLVTGPTGSGKSTTLAAMIDYINETRSKHIITIEDPIEFVHKHKKSLINQREVGRDTE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 187 SYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDRIIDVFPPEQQQQVRIQLSTVLRAV 266
Cdd:cd01131    82 SFAAALRAALREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIIDVFPPEQQEQVRIQLASSLRGV 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717219873 267 ISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISMDKYISNLY 327
Cdd:cd01131   162 ISQRLLPKKDGGgRVAAFEILINTPAIRNLIREGKTHQIPSLIQTGARDGMQTMDQSLYELY 223
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
 83-273 4.96e-42

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 147.43  E-value: 4.96e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  83 RFRVSTYIQRGSVAAVLRVLPF--GDLDFEEY----NIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINkTRSC 156
Cdd:pfam00437  81 RVRVSTLPTAGGEKLVIRLLDPsnVALSLDELgmtgAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELN-TRDE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 157 HILTLEDPIEYLFKHDKAIVDQREIGIDtksYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSA 236
Cdd:pfam00437 160 NIVTVEDPVEIQLEGINQVQLNARAGVT---FADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSA 236

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1717219873 237 SKTVDRIID-VFPPEqqqqvriQLSTVLRAVISQQLLP 273
Cdd:pfam00437 237 AGALTRLQDmGVPPF-------ELASSLLLVIAQRLVR 267
PRK10436 PRK10436
hypothetical protein; Provisional
 4-319 1.27e-30

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 121.19  E-value: 1.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   4 LDELLELSVKKNASDIFI---SVGIKPSLKING---EIYSIYDEIIKPIDSETLVreMYKLN-PEKFLKfkEKGEddFSI 76
Cdd:PRK10436   88 INQTLQSALQKRASDIHFepaQNHYRIRLRIDGvlhPLPDPSPELGAALTARLKV--LGNLDiAERRLP--QDGQ--FTV 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  77 SRAGVG-RFRVSTYIQRGSVAAVLRVLPFGD--LDFEEYNIPASIVD--ISTYN--KGLVIVTGATGTGKSTTLATIINM 149
Cdd:PRK10436  162 ELAGNAySFRIATLPCRGGEKVVLRLLQQVQqaLDLETLGMTPAQLAqfRQALQqpQGLILVTGPTGSGKTVTLYSALQT 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 150 INKTRScHILTLEDPIEylfkhdkaI----VDQREI----GIDtksYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAA 221
Cdd:PRK10436  242 LNTAQI-NICSVEDPVE--------IplagINQTQIhpkaGLT---FQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAA 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 222 ETGHLVLSTLHTTSASKTVDRIidvfppeQQQQV-RIQLSTVLRAVISQQLL------------------PTVDQK---- 278
Cdd:PRK10436  310 QTGHLVLSTLHTNSTSETLVRL-------QQMGIaRWMLASALKLVIAQRLVrklcphcrqqasepihlpPNIWPGplph 382

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717219873 279 ---------------RIAAFEVMYVNTAIKNLIRDSkiPQIDAMIQTGASEGMISM 319
Cdd:PRK10436  383 wqavgcehcyhgyygRTALFEVLPITPVLQQAIASN--ASPEELETHARQQGMTTL 436
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 129-208 2.59e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 38.12  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  129 VIVTGATGTGKSTTLATIINMINKT-RSCHILTLEDPIE--YLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFL 205
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPgGGVIYIDGEDILEevLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLIL 84


                   ...
gi 1717219873  206 GEM 208
Cdd:smart00382  85 DEI 87
 
Name Accession Description Interval E-value
PilT COG2805
Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular ...
 1-342 0e+00

Type IV pilus assembly protein PilT, pilus retraction ATPase [Cell motility, Extracellular structures];


Pssm-ID: 442056  Cd Length: 342  Bit Score: 534.29  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   1 MITLDELLELSVKKNASDIFISVGIKPSLKINGEIYSIYDEIIKPIDSETLVREMykLNPEKFLKFKEKGEDDFSISRAG 80
Cdd:COG2805     2 AMDLDELLKLAVEQGASDLHLTVGSPPMLRIDGELVPLDDPPLTPEDLEALLKEI--LTEEQRERLEEEGELDFSYSLPG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  81 VGRFRVSTYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILT 160
Cdd:COG2805    80 LGRFRVNIFRQRGGVAAVLRLIPSEIPTLEELGLPPVLKELAELPRGLVLVTGPTGSGKSTTLAAMIDYINETRAKHIIT 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 161 LEDPIEYLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTV 240
Cdd:COG2805   160 IEDPIEFVHKHKKSLINQREVGRDTPSFANALRAALREDPDVILVGEMRDLETIEAALTAAETGHLVFATLHTNSAAQTI 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 241 DRIIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISM 319
Cdd:COG2805   240 DRIIDVFPPEEQAQIRSQLAESLRGVISQRLLPRADGGgRVAAREILVNTPAVRNLIREGKTHQIPSLIQTGKKLGMQTM 319

                         330       340
                  ....*....|....*....|...
gi 1717219873 320 DKYISNLYNYGTITRETAIKYAS 342
Cdd:COG2805   320 DQSLAELVKEGLITEETALAYAS 342
pilT_fam TIGR01420
pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to ...
 3-345 1.30e-154

pilus retraction protein PilT; This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility]


Pssm-ID: 273613  Cd Length: 343  Bit Score: 437.91  E-value: 1.30e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   3 TLDELLELSVKKNASDIFISVGIKPSLKINGEIYSIYDEIIKPIDSETLVREMykLNPEKFLKFKEKGEDDFSISRAGVG 82
Cdd:TIGR01420   1 SLEEILREAVKLGASDIHLTAGAPPAMRIDGDLVRIEFEPLTPEDTQKLAREI--LSEKQREEFEENGELDFSFSLPGVG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  83 RFRVSTYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILTLE 162
Cdd:TIGR01420  79 RFRVNAFYQRGGVALVLRLIPSKIPTFEELGLPPVLRELAERPRGLILVTGPTGSGKSTTLASMIDYINKNKAYHIITIE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 163 DPIEYLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDR 242
Cdd:TIGR01420 159 DPIEYVHTNKRSLINQREVGEDTLSFANALRAALREDPDVILIGEMRDLETVELALTAAETGHLVFGTLHTNSAAQTIER 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 243 IIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISMDK 321
Cdd:TIGR01420 239 IIDVFPAEEQEQIRTQLAESLVAIISQRLLPKADGGgRVLAVEILINTPAVRNLIREGKTHQIKSLIQTGQQLGMQTFDQ 318

                         330       340
                  ....*....|....*....|....
gi 1717219873 322 YISNLYNYGTITRETAIKYASNAE 345
Cdd:TIGR01420 319 HLAQLYKKGLITLEDALEAAPSPH 342
PilU COG5008
Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];
3-341 1.93e-145

Type IV pilus assembly protein, ATPase PilU [Cell motility, Extracellular structures];


Pssm-ID: 444032  Cd Length: 370  Bit Score: 415.65  E-value: 1.93e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   3 TLDELLELSVKKNASDIFISVGIKPSLKINGEIYSIYDEIIKPIDSETLVREMykLNPEKFLKFKEKGEDDFSISRAGVG 82
Cdd:COG5008     2 DLEDLLKLMVEKKASDLFITAGAPPSIKIDGKLTPLSQQPLTPEQVRELAYSI--MNEEQREEFERTKECNFAISLPGVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  83 RFRVSTYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILTLE 162
Cdd:COG5008    80 RFRVNAFRQRGSVGMVLRRIETEIPTLDELGLPPVLKDLIMEKRGLVLFVGATGSGKSTTLAAMIDHRNENSSGHILTIE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 163 DPIEYLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDR 242
Cdd:COG5008   160 DPIEFVHKHKKSIVTQREVGVDTESYEVALKNALRQAPDVILIGEIRDRETMEHAIAFAETGHLCLATLHANNANQALDR 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 243 IIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQKRIAAFEVMyVNTA-IKNLIRDSKIPQI-DAMIQTGAsEGMISMD 320
Cdd:COG5008   240 IINFFPEERRPQLLMDLSLNLRAIVSQRLVPTKDGGRVAAVEVL-LNTPlIADLIRKGEIHEIkEAMEKSRE-LGMQTFD 317

                         330       340
                  ....*....|....*....|.
gi 1717219873 321 KYISNLYNYGTITRETAIKYA 341
Cdd:COG5008   318 QALFRLYEAGKISYEEALRNA 338
PilT cd01131
Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein ...
 107-327 2.19e-128

Pilus retraction ATPase PilT; Pilus retraction ATPase PilT is a nucleotide-binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism known as twitching motility.


Pssm-ID: 410875 [Multi-domain]  Cd Length: 223  Bit Score: 366.48  E-value: 2.19e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 107 LDFEEYNIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINKTRSCHILTLEDPIEYLFKHDKAIVDQREIGIDTK 186
Cdd:cd01131     2 PTFEELGLPPVLKDLALKPRGLVLVTGPTGSGKSTTLAAMIDYINETRSKHIITIEDPIEFVHKHKKSLINQREVGRDTE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 187 SYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDRIIDVFPPEQQQQVRIQLSTVLRAV 266
Cdd:cd01131    82 SFAAALRAALREDPDVILVGEMRDLETIELALTAAETGHLVFSTLHTNSAAQTIDRIIDVFPPEQQEQVRIQLASSLRGV 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1717219873 267 ISQQLLPTVDQK-RIAAFEVMYVNTAIKNLIRDSKIPQIDAMIQTGASEGMISMDKYISNLY 327
Cdd:cd01131   162 ISQRLLPKKDGGgRVAAFEILINTPAIRNLIREGKTHQIPSLIQTGARDGMQTMDQSLYELY 223
DotB_TraJ cd19516
dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of ...
 127-284 6.32e-55

dot/icm secretion system protein DotB-like; Defect in organelle trafficking (Dot)B is part of the type IVb secretion (T4bS) system, also known as the dot/icm system, and is the main energy supplier of the secretion system. It is an ATPase, similar to the VirB11 component of the T4aS systems. This family also includes Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ encoded on the tra (transfer) operon.


Pssm-ID: 410924 [Multi-domain]  Cd Length: 179  Bit Score: 177.95  E-value: 6.32e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 127 GLVIVTGATGTGKSTTLATIIN--MINKTRSCHILTLEDPIEYLF---KHDKAIVDQREIGIDTKSYVSALRSALRQAPD 201
Cdd:cd19516    12 GLVYVAGATGSGKSTLLAAIYRyiLENDPPDRKIITYEDPIEFVYdgiKSKHSIIVQSQIPRHFKSFAKAVREALRRKPS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 202 VIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDRIIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQKRIA 281
Cdd:cd19516    92 LIGVGELRDQETISAAVEASLTGHPVYSTVHTKSVAETIRRLISLFPPEERDAAAYDLLSTLRFIIVQRLVRTTDGKRVA 171


                  ...
gi 1717219873 282 AFE 284
Cdd:cd19516   172 VRE 174
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
 127-289 1.74e-50

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 165.74  E-value: 1.74e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 127 GLVIVTGATGTGKSTTLATIINMINKTRsCHILTLEDPIEYlfKHDKAIVDQ--REIGIDtksYVSALRSALRQAPDVIF 204
Cdd:cd01129    12 GLILVTGPTGSGKTTTLYAMLRELNGPE-RNIITIEDPVEY--QIPGINQSQvnEKIGLT---FADALRAILRQDPDIIM 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 205 LGEMRDFETMSIAMTAAETGHLVLSTLHTTSASKTVDRIIDVF-PPEqqqqvriQLSTVLRAVISQQLLptvdqKRIAAF 283
Cdd:cd01129    86 VGEIRDAETAEIAIRAALTGHLVLSTLHTNDALGAITRLLDMGiEPF-------LLASALRGVIAQRLV-----GRTAIA 153


                  ....*.
gi 1717219873 284 EVMYVN 289
Cdd:cd01129   154 EVLVLD 159
PulE COG2804
Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell ...
 84-319 7.62e-49

Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB [Cell motility, Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442055 [Multi-domain]  Cd Length: 561  Bit Score: 172.30  E-value: 7.62e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  84 FRVSTYIQRGSVAAVLRVL-------PFGDLDFEEYNIpASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINkTRSC 156
Cdd:COG2804   265 LRVSTLPTVYGEKVVLRILdksaallDLEQLGFSPDQL-ERLRRLIRRPHGIILVTGPTGSGKTTTLYAALNELN-TPER 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 157 HILTLEDPIEYLFKHdkaiVDQ----REIGIDtksYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLH 232
Cdd:COG2804   343 NIITVEDPVEYQLPG----INQvqvnPKIGLT---FASALRSILRQDPDVIMVGEIRDLETAEIAVQAALTGHLVLSTLH 415

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 233 TTSASKTVDRIIDV-FPPEqqqqvriQLSTVLRAVISQQLL------------PTVDQK--------------------- 278
Cdd:COG2804   416 TNDAPSAITRLLDMgVEPF-------LLASSLLGVLAQRLVrrlcphckepyePDPEELerlglppeelapltfyrgvgc 488

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1717219873 279 ----------RIAAFEVMYVNTAIKNLIRDSKipQIDAMIQTGASEGMISM 319
Cdd:COG2804   489 ehcngtgykgRTGIYELLVIDDELRELIAEGA--SAAELREAARKEGMRTL 537
T2SSE pfam00437
Type II/IV secretion system protein; This family contains components of both the Type II ...
 83-273 4.96e-42

Type II/IV secretion system protein; This family contains components of both the Type II protein secretion system (T2SS), including Type 4 pilus (T4P), and Type IV protein secretion system (T4SS) from Gram-negative bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection. The cytoplasmic T2S E ATPase is a Zn-containing protein thought to provide the mechanical force for the secretion process. T2S-E contains Walker A and B motifs, that are essential for secretion and ATPase activity. ATPase PulE and XcpR from Klebsiella oxytoca and Pseudomonas aeruginosa respectively are required for protein secretion via the T2SS. ATPase PilB is required for T4P extension.


Pssm-ID: 425681 [Multi-domain]  Cd Length: 269  Bit Score: 147.43  E-value: 4.96e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  83 RFRVSTYIQRGSVAAVLRVLPF--GDLDFEEY----NIPASIVDISTYNKGLVIVTGATGTGKSTTLATIINMINkTRSC 156
Cdd:pfam00437  81 RVRVSTLPTAGGEKLVIRLLDPsnVALSLDELgmtgAQDEALLEFLRQPRGNILVTGPTGSGKTTTLYAALGELN-TRDE 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 157 HILTLEDPIEYLFKHDKAIVDQREIGIDtksYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAAETGHLVLSTLHTTSA 236
Cdd:pfam00437 160 NIVTVEDPVEIQLEGINQVQLNARAGVT---FADLLRAILRQDPDRIMVGEIRDLETAEIALQAANTGHLVLSTLHTNSA 236

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1717219873 237 SKTVDRIID-VFPPEqqqqvriQLSTVLRAVISQQLLP 273
Cdd:pfam00437 237 AGALTRLQDmGVPPF-------ELASSLLLVIAQRLVR 267
plasmid_TraJ TIGR02525
plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated ...
 2-308 2.20e-41

plasmid transfer ATPase TraJ; Members of this protein family are predicted ATPases associated with plasmid transfer loci in bacteria. This family is most similar to the DotB ATPase of a type-IV secretion-like system of obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii (TIGR02524). [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 131577 [Multi-domain]  Cd Length: 372  Bit Score: 148.41  E-value: 2.20e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   2 ITLDELLELSV---KKNASDIFISVGIKPSLKINGE--IYSIYdeiikPIDSETLVREMYKL-NPE------------KF 63
Cdd:TIGR02525   7 LTADTLRRFFVhcsRHEVSDIHLQGGSPIVVERHGRqvPASSF-----PLDNLELERLVDEVfGPEikptvksgapvdRA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  64 LKFKEKGEDDFSISRAGVGRFRV-----STYIQRGSVAAVLRVLPFGDLDFEEYNIPASIVDISTYNKGLVIVTGATGTG 138
Cdd:TIGR02525  82 IQLRGDENGRYGLGRGERVRFRCnfiqaTIGKLETAISLTLRVIPSDIPDLKQMGIEPDLFNSLLPAAGLGLICGETGSG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 139 KSTTLATIINMINKT-RSCHILTLEDPIEYLF--KHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRDFETMS 215
Cdd:TIGR02525 162 KSTLAASIYQHCGETyPDRKIVTYEDPIEYILgsPDDLLPPAQSQIGRDVDSFANGIRLALRRAPKIIGVGEIRDLETFQ 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 216 IAMTAAETGHLVLSTLHTTSASKTVDRIIDVFPPEQQQQVRIQLSTVLRAVISQQLLPTVDQKRIAAFEVMYVNTAIKNL 295
Cdd:TIGR02525 242 AAVLAGQSGHFCLGTLHVKSPGEAISRCLQMYPPEMREAAAFDLLSILQYIIVQRLLRTTDGKRQAVREYIVFDDSLRRK 321

                         330
                  ....*....|....*..
gi 1717219873 296 IRDSKIPQ----IDAMI 308
Cdd:TIGR02525 322 LYDVDYSKwgryIDDIL 338
PRK10436 PRK10436
hypothetical protein; Provisional
 4-319 1.27e-30

hypothetical protein; Provisional


Pssm-ID: 236694  Cd Length: 462  Bit Score: 121.19  E-value: 1.27e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873   4 LDELLELSVKKNASDIFI---SVGIKPSLKING---EIYSIYDEIIKPIDSETLVreMYKLN-PEKFLKfkEKGEddFSI 76
Cdd:PRK10436   88 INQTLQSALQKRASDIHFepaQNHYRIRLRIDGvlhPLPDPSPELGAALTARLKV--LGNLDiAERRLP--QDGQ--FTV 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  77 SRAGVG-RFRVSTYIQRGSVAAVLRVLPFGD--LDFEEYNIPASIVD--ISTYN--KGLVIVTGATGTGKSTTLATIINM 149
Cdd:PRK10436  162 ELAGNAySFRIATLPCRGGEKVVLRLLQQVQqaLDLETLGMTPAQLAqfRQALQqpQGLILVTGPTGSGKTVTLYSALQT 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 150 INKTRScHILTLEDPIEylfkhdkaI----VDQREI----GIDtksYVSALRSALRQAPDVIFLGEMRDFETMSIAMTAA 221
Cdd:PRK10436  242 LNTAQI-NICSVEDPVE--------IplagINQTQIhpkaGLT---FQRVLRALLRQDPDVIMVGEIRDGETAEIAIKAA 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 222 ETGHLVLSTLHTTSASKTVDRIidvfppeQQQQV-RIQLSTVLRAVISQQLL------------------PTVDQK---- 278
Cdd:PRK10436  310 QTGHLVLSTLHTNSTSETLVRL-------QQMGIaRWMLASALKLVIAQRLVrklcphcrqqasepihlpPNIWPGplph 382

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1717219873 279 ---------------RIAAFEVMYVNTAIKNLIRDSkiPQIDAMIQTGASEGMISM 319
Cdd:PRK10436  383 wqavgcehcyhgyygRTALFEVLPITPVLQQAIASN--ASPEELETHARQQGMTTL 436
type_II_IV_secretion_ATPases cd19477
type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP ...
 127-245 1.14e-23

type II/type IV hexameric secretion ATPases; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410885 [Multi-domain]  Cd Length: 168  Bit Score: 95.92  E-value: 1.14e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 127 GLVIVTGATGTGKSTTLATIINMINKTRscHILTLEDPIEYLFKHDKAIvDQREIGiDTKSYVSALRSALRQAPDVIFLG 206
Cdd:cd19477    11 KNVIVCGGTGSGKTTYIKSILEFIPKEE--RIISIEDTEEIVFKHHKNY-TQLFFG-GNITSADCLKSCLRQRPDRIILG 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1717219873 207 EMRDfETMSIAMTAAETGH-LVLSTLHTTSASKTVDRIID 245
Cdd:cd19477    87 ELRS-SEAYDFYNVLCSGHkGTLTTLHAGSSEEAFIRLAN 125
VirB11-like_ATPase cd01130
Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, ...
 129-244 4.72e-17

Type IV secretory pathway component VirB11-like; Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir (virulence) proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the bacterial Ti (tumor-inducing)-plasmid into plant cells. The pilus is a fibrous cell surface organelle, which mediates adhesion between bacteria during conjugative transfer or between bacteria and host eukaryotic cells during infection. VirB11-related ATPases include Sulfolobus acidocaldarius FlaI, which plays key roles in archaellum (archaeal flagellum) assembly and motility functions, and the pilus assembly proteins CpaF/TadA and TrbB. This alignment contains the C-terminal domain, which is the ATPase.


Pssm-ID: 410874 [Multi-domain]  Cd Length: 177  Bit Score: 77.97  E-value: 4.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 129 VIVTGATGTGKSTTLATIINMINKTRscHILTLEDPIEYLFKHD---KAIVDQREIGIDTKSYVSALRSALRQAPDVIFL 205
Cdd:cd01130    15 ILISGGTGSGKTTLLNALLSFIPPDE--RIVTIEDTRELQLPHPnvvHLLTRPGGGEKGEVTMADLLKAALRMRPDRIIV 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1717219873 206 GEMRDFETMSiAMTAAETGHL-VLSTLHTTSASKTVDRII 244
Cdd:cd01130    93 GEVRGGEAYD-MLQAMNTGHPgSITTIHANSAEDAIDRLA 131
VirB11 COG0630
Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell ...
 125-245 1.14e-12

Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase ArlI/FlaI [Cell motility, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440395 [Multi-domain]  Cd Length: 462  Bit Score: 68.57  E-value: 1.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 125 NKGLVIVTGATGTGKSTTLATIINMINKTRSchILTLEDPIEYLFKHDKAIvdQ---REIGIDTKSYVS---ALRSALRQ 198
Cdd:COG0630   289 NGKSVLVAGGTASGKTTLLNALLSFIPPDAK--IVTIEDTRELNLPHENWI--SlvtRESFGGEEGDVTmfdLLKAALRQ 364

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1717219873 199 APDVIFLGEMRDFEtMSIAMTAAETGHLVLSTLHTTSASKTVDRIID 245
Cdd:COG0630   365 RPDYIVVGEVRGEE-AYTLFQAMATGHGVLSTFHADSVESAINRLTS 410
CpaF COG4962
Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and ...
 129-243 1.74e-11

Pilus assembly protein, ATPase of CpaF family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443988 [Multi-domain]  Cd Length: 386  Bit Score: 64.80  E-value: 1.74e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 129 VIVTGATGTGKSTTLATIINMINKTRscHILTLEDPIEYLFKHD--------------KAIVDQREIgidtksyvsaLRS 194
Cdd:COG4962   185 ILVSGGTGSGKTTLLNALSGFIPPDE--RIVTIEDAAELQLQHPhvvrletrppnvegAGEVTLRDL----------VRN 252

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1717219873 195 ALRQAPDVIFLGEMRDFE--TMSIAMTaaeTGHL-VLSTLHTTSASKTVDRI 243
Cdd:COG4962   253 ALRMRPDRIIVGEVRGAEalDMLQAMN---TGHDgSMSTLHANSARDALARL 301
PRK13894 PRK13894
conjugal transfer ATPase TrbB; Provisional
 74-243 4.87e-08

conjugal transfer ATPase TrbB; Provisional


Pssm-ID: 184377  Cd Length: 319  Bit Score: 53.98  E-value: 4.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  74 FSISRAGVGRFRVSTYIQRGSVAAVLRvlpfgdldfeeynipASIVD-ISTYNKGLVIvtGATGTGKSTTLATIIN-MIn 151
Cdd:PRK13894  112 FAIRKKAVAIFTLDQYVERGIMTAAQR---------------EAIIAaVRAHRNILVI--GGTGSGKTTLVNAIINeMV- 173

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 152 ktrschiltLEDPIEYLFkhdkAIVDQREIGIDTKSYV-----------SALRSALRQAPDVIFLGEMRDFETMSIAMtA 220
Cdd:PRK13894  174 ---------IQDPTERVF----IIEDTGEIQCAAENYVqyhtsidvnmtALLKTTLRMRPDRILVGEVRGPEALDLLM-A 239

                         170       180
                  ....*....|....*....|....
gi 1717219873 221 AETGHL-VLSTLHTTSASKTVDRI 243
Cdd:PRK13894  240 WNTGHEgGAATLHANNAKAGLDRL 263
PRK13851 PRK13851
type IV secretion system protein VirB11; Provisional
 96-210 8.26e-08

type IV secretion system protein VirB11; Provisional


Pssm-ID: 172375  Cd Length: 344  Bit Score: 53.36  E-value: 8.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  96 AAVLRVLPFGDLdfeEYNIPASIVDISTynkglVIVTGATGTGKSTTLATIINMInkTRSCHILTLEDPIEYLFKHD--- 172
Cdd:PRK13851  140 EAILRHYDNGDL---EAFLHACVVGRLT-----MLLCGPTGSGKTTMSKTLISAI--PPQERLITIEDTLELVIPHEnhv 209

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1717219873 173 KAIVDQREIGIDTKSYVSALRSALRQAPDVIFLGEMRD 210
Cdd:PRK13851  210 RLLYSKNGAGLGAVTAEHLLQASLRMRPDRILLGEMRD 247
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 129-208 2.59e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 38.12  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873  129 VIVTGATGTGKSTTLATIINMINKT-RSCHILTLEDPIE--YLFKHDKAIVDQREIGIDTKSYVSALRSALRQAPDVIFL 205
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPgGGVIYIDGEDILEevLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLIL 84


                   ...
gi 1717219873  206 GEM 208
Cdd:smart00382  85 DEI 87
PRK13900 PRK13900
type IV secretion system ATPase VirB11; Provisional
 125-294 3.65e-03

type IV secretion system ATPase VirB11; Provisional


Pssm-ID: 184381  Cd Length: 332  Bit Score: 38.97  E-value: 3.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 125 NKGLVIVTGATGTGKSTTLATIINMINKTRscHILTLEDPIE-YLFKHDKAIVDQREIGIDTKSYVSA---LRSALRQAP 200
Cdd:PRK13900  159 SKKNIIISGGTSTGKTTFTNAALREIPAIE--RLITVEDAREiVLSNHPNRVHLLASKGGQGRAKVTTqdlIEACLRLRP 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 201 DVIFLGEMRDFETMSIaMTAAETGHL-VLSTLHTTSASKTVDRIIDV-------FPPEqqqQVRIQLSTVLRAVIsqQLL 272
Cdd:PRK13900  237 DRIIVGELRGAEAFSF-LRAINTGHPgSISTLHADSPAMAIEQLKLMvmqaglgMPPD---QIKKYILNVVDIVV--QLK 310

                         170       180
                  ....*....|....*....|..
gi 1717219873 273 PTVDQKRIAAfEVMYVNTAIKN 294
Cdd:PRK13900  311 RGSGGKRYVS-EIYFTKNKNKN 331
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
128-211 8.59e-03

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 37.20  E-value: 8.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1717219873 128 LVIVTGATGTGKsTTLAT--IINMINKTRSCHILTLEDPIEYLFKhdkaivDQREIGIDTKSYVSALRSALRQAPDVIFL 205
Cdd:COG0467    22 STLLSGPPGTGK-TTLALqfLAEGLRRGEKGLYVSFEESPEQLLR------RAESLGLDLEEYIESGLLRIIDLSPEELG 94


                  ....*.
gi 1717219873 206 GEMRDF 211
Cdd:COG0467    95 LDLEEL 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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