NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1740152963|ref|WP_149049686|]
View 

MucBP domain-containing protein [Listeria monocytogenes]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Big_3 pfam07523
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
477-542 1.43e-23

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


:

Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 94.29  E-value: 1.43e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1740152963 477 KAHDSTIYVGDKWSAEDNFDSAVNSVGAA-VSFDDVEVEGTVDTTKAGVYPVTYSFAGESVTINVTV 542
Cdd:pfam07523   1 QPHKTTYYVGDSWDAEDNFVSATYKDGDAeVPFDDVEVSGTVDSTKAGEYTVTYTYKGVSATFTVTV 67
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
408-470 1.85e-19

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


:

Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 82.39  E-value: 1.85e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1740152963 408 TVKYVDENGNEITTSDTLTGKLDDSYQAKAKEIAGFTLDNSKLPA--NASGVFETNPQTVTYVYQ 470
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKEIPGYTLVETPGNAtgNATGTFTEEPQTVTYVYT 65
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
334-400 5.48e-17

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


:

Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 75.46  E-value: 5.48e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1740152963 334 TVNYVDEAGAEIHEPQTVSGNVGDDYDVTTPEfelsIDKYELDTEQMPTNG--IGTLSSEAQTVTYVYK 400
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKE----IPGYTLVETPGNATGnaTGTFTEEPQTVTYVYT 65
PLN00113 super family cl33413
leucine-rich repeat receptor-like protein kinase; Provisional
87-179 3.05e-15

leucine-rich repeat receptor-like protein kinase; Provisional


The actual alignment was detected with superfamily member PLN00113:

Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.51  E-value: 3.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  87 DLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLGNISEIA-- 164
Cdd:PLN00113  186 NLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQyl 265
                          90
                  ....*....|....*.
gi 1740152963 165 -LQNNRLVGQIPLSLY 179
Cdd:PLN00113  266 fLYQNKLSGPIPPSIF 281
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-196 9.28e-11

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 9.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963   4 AFLCLSAVVLSLNFVWVNPLSGLASKIETTKLKSTMDTNQQVNLKNNATDIVTSEDLGGQTWLINEVNRQLAPKKVGVDL 83
Cdd:COG4886    11 KLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  84 TFDDLAKIKIISLSNksltgevPPEIKNLVSLEKLLLYSNKLSgEIPAELGELTNLSELRLDYNQFT--GKILDGLGNIS 161
Cdd:COG4886    91 DLGDLTNLTELDLSG-------NEELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTdlPEPLGNLTNLK 162
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1740152963 162 EIALQNNRLvGQIPLSLyENRTGENEVNVSGNQVT 196
Cdd:COG4886   163 SLDLSNNQL-TDLPEEL-GNLTNLKELDLSNNQIT 195
 
Name Accession Description Interval E-value
Big_3 pfam07523
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
477-542 1.43e-23

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 94.29  E-value: 1.43e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1740152963 477 KAHDSTIYVGDKWSAEDNFDSAVNSVGAA-VSFDDVEVEGTVDTTKAGVYPVTYSFAGESVTINVTV 542
Cdd:pfam07523   1 QPHKTTYYVGDSWDAEDNFVSATYKDGDAeVPFDDVEVSGTVDSTKAGEYTVTYTYKGVSATFTVTV 67
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
408-470 1.85e-19

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 82.39  E-value: 1.85e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1740152963 408 TVKYVDENGNEITTSDTLTGKLDDSYQAKAKEIAGFTLDNSKLPA--NASGVFETNPQTVTYVYQ 470
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKEIPGYTLVETPGNAtgNATGTFTEEPQTVTYVYT 65
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
334-400 5.48e-17

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 75.46  E-value: 5.48e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1740152963 334 TVNYVDEAGAEIHEPQTVSGNVGDDYDVTTPEfelsIDKYELDTEQMPTNG--IGTLSSEAQTVTYVYK 400
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKE----IPGYTLVETPGNATGnaTGTFTEEPQTVTYVYT 65
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
87-179 3.05e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.51  E-value: 3.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  87 DLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLGNISEIA-- 164
Cdd:PLN00113  186 NLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQyl 265
                          90
                  ....*....|....*.
gi 1740152963 165 -LQNNRLVGQIPLSLY 179
Cdd:PLN00113  266 fLYQNKLSGPIPPSIF 281
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-196 1.96e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 69.58  E-value: 1.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  85 FDDLAKIKIISLSNKSLTgEVPPEIKNLVSLEKLLLYSNKLSgEIPAELGELTNLSELRLDYNQFT--GKILDGLGNISE 162
Cdd:COG4886   155 LGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTdlPEPLANLTNLET 232
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1740152963 163 IALQNNRLVgQIPlSLyENRTGENEVNVSGNQVT 196
Cdd:COG4886   233 LDLSNNQLT-DLP-EL-GNLTNLEELDLSNNQLT 263
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-196 9.28e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 9.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963   4 AFLCLSAVVLSLNFVWVNPLSGLASKIETTKLKSTMDTNQQVNLKNNATDIVTSEDLGGQTWLINEVNRQLAPKKVGVDL 83
Cdd:COG4886    11 KLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  84 TFDDLAKIKIISLSNksltgevPPEIKNLVSLEKLLLYSNKLSgEIPAELGELTNLSELRLDYNQFT--GKILDGLGNIS 161
Cdd:COG4886    91 DLGDLTNLTELDLSG-------NEELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTdlPEPLGNLTNLK 162
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1740152963 162 EIALQNNRLvGQIPLSLyENRTGENEVNVSGNQVT 196
Cdd:COG4886   163 SLDLSNNQL-TDLPEEL-GNLTNLKELDLSNNQIT 195
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
88-170 1.53e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.54  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  88 LAKIKIISLSNKSLTgevppEIKNL---VSLEKLLLYSNKLSgEIPAeLGELTNLSELRLDYNQFTgKI--LDGLGNISE 162
Cdd:cd21340     1 LKRITHLYLNDKNIT-----KIDNLslcKNLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNNQIE-KIenLENLVNLKK 72

                  ....*...
gi 1740152963 163 IALQNNRL 170
Cdd:cd21340    73 LYLGGNRI 80
LRR_8 pfam13855
Leucine rich repeat;
90-149 4.47e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 4.47e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1740152963  90 KIKIISLSNKSLTGeVPPEI-KNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQF 149
Cdd:pfam13855   2 NLRSLDLSNNRLTS-LDDGAfKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
Big_3 pfam07523
Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like ...
477-542 1.43e-23

Bacterial Ig-like domain (group 3); This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.


Pssm-ID: 400072 [Multi-domain]  Cd Length: 67  Bit Score: 94.29  E-value: 1.43e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1740152963 477 KAHDSTIYVGDKWSAEDNFDSAVNSVGAA-VSFDDVEVEGTVDTTKAGVYPVTYSFAGESVTINVTV 542
Cdd:pfam07523   1 QPHKTTYYVGDSWDAEDNFVSATYKDGDAeVPFDDVEVSGTVDSTKAGEYTVTYTYKGVSATFTVTV 67
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
408-470 1.85e-19

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 82.39  E-value: 1.85e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1740152963 408 TVKYVDENGNEITTSDTLTGKLDDSYQAKAKEIAGFTLDNSKLPA--NASGVFETNPQTVTYVYQ 470
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKEIPGYTLVETPGNAtgNATGTFTEEPQTVTYVYT 65
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
334-400 5.48e-17

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 75.46  E-value: 5.48e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1740152963 334 TVNYVDEAGAEIHEPQTVSGNVGDDYDVTTPEfelsIDKYELDTEQMPTNG--IGTLSSEAQTVTYVYK 400
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKE----IPGYTLVETPGNATGnaTGTFTEEPQTVTYVYT 65
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
87-179 3.05e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.51  E-value: 3.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  87 DLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLGNISEIA-- 164
Cdd:PLN00113  186 NLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQyl 265
                          90
                  ....*....|....*.
gi 1740152963 165 -LQNNRLVGQIPLSLY 179
Cdd:PLN00113  266 fLYQNKLSGPIPPSIF 281
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
89-178 2.58e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 76.81  E-value: 2.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  89 AKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKI---LDGLGNISEIAL 165
Cdd:PLN00113  164 SSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIpyeIGGLTSLNHLDL 243
                          90
                  ....*....|...
gi 1740152963 166 QNNRLVGQIPLSL 178
Cdd:PLN00113  244 VYNNLTGPIPSSL 256
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
88-178 3.64e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 76.04  E-value: 3.64e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  88 LAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGL---GNISEIA 164
Cdd:PLN00113  307 LQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLcssGNLFKLI 386
                          90
                  ....*....|....
gi 1740152963 165 LQNNRLVGQIPLSL 178
Cdd:PLN00113  387 LFSNSLEGEIPKSL 400
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-196 1.96e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 69.58  E-value: 1.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  85 FDDLAKIKIISLSNKSLTgEVPPEIKNLVSLEKLLLYSNKLSgEIPAELGELTNLSELRLDYNQFT--GKILDGLGNISE 162
Cdd:COG4886   155 LGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTdlPEPLANLTNLET 232
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1740152963 163 IALQNNRLVgQIPlSLyENRTGENEVNVSGNQVT 196
Cdd:COG4886   233 LDLSNNQLT-DLP-EL-GNLTNLEELDLSNNQLT 263
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
81-175 5.62e-12

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 69.11  E-value: 5.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  81 VDLTFDDLAKIKIISLSNKSLTGEVPPEI---KNLVSLEkllLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGL 157
Cdd:PLN00113  491 VPRKLGSLSELMQLKLSENKLSGEIPDELsscKKLVSLD---LSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNL 567
                          90       100
                  ....*....|....*....|.
gi 1740152963 158 GNIS---EIALQNNRLVGQIP 175
Cdd:PLN00113  568 GNVEslvQVNISHNHLHGSLP 588
PLN03150 PLN03150
hypothetical protein; Provisional
80-178 5.66e-12

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 68.69  E-value: 5.66e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  80 GVDLTFDDLAK---IKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDG 156
Cdd:PLN03150  406 GADCQFDSTKGkwfIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPES 485
                          90       100
                  ....*....|....*....|....*
gi 1740152963 157 LGNISE---IALQNNRLVGQIPLSL 178
Cdd:PLN03150  486 LGQLTSlriLNLNGNSLSGRVPAAL 510
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
4-196 9.28e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.18  E-value: 9.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963   4 AFLCLSAVVLSLNFVWVNPLSGLASKIETTKLKSTMDTNQQVNLKNNATDIVTSEDLGGQTWLINEVNRQLAPKKVGVDL 83
Cdd:COG4886    11 KLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  84 TFDDLAKIKIISLSNksltgevPPEIKNLVSLEKLLLYSNKLSgEIPAELGELTNLSELRLDYNQFT--GKILDGLGNIS 161
Cdd:COG4886    91 DLGDLTNLTELDLSG-------NEELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQLTdlPEPLGNLTNLK 162
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1740152963 162 EIALQNNRLvGQIPLSLyENRTGENEVNVSGNQVT 196
Cdd:COG4886   163 SLDLSNNQL-TDLPEEL-GNLTNLKELDLSNNQIT 195
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
67-185 1.04e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 64.87  E-value: 1.04e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  67 INEVNRQLAPKKVgvDLTFDDLAKIKIISLSNKSLTGEVPPeiKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDY 146
Cdd:PLN00113   98 INLSNNQLSGPIP--DDIFTTSSSLRYLNLSNNNFTGSIPR--GSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGG 173
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1740152963 147 NQFTGKILDGLGNISEI---ALQNNRLVGQIPLSL------------YENRTGE 185
Cdd:PLN00113  174 NVLVGKIPNSLTNLTSLeflTLASNQLVGQIPRELgqmkslkwiylgYNNLSGE 227
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
84-178 1.36e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 64.48  E-value: 1.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  84 TFDDLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLGNISE- 162
Cdd:PLN00113  255 SLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRl 334
                          90
                  ....*....|....*...
gi 1740152963 163 --IALQNNRLVGQIPLSL 178
Cdd:PLN00113  335 qvLQLWSNKFSGEIPKNL 352
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
90-193 1.87e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 64.10  E-value: 1.87e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  90 KIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLGN---ISEIALQ 166
Cdd:PLN00113  476 RLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEmpvLSQLDLS 555
                          90       100
                  ....*....|....*....|....*..
gi 1740152963 167 NNRLVGQIPLSLyENRTGENEVNVSGN 193
Cdd:PLN00113  556 QNQLSGEIPKNL-GNVESLVQVNISHN 581
PLN03150 PLN03150
hypothetical protein; Provisional
88-158 3.28e-10

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 62.91  E-value: 3.28e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1740152963  88 LAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLG 158
Cdd:PLN03150  441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
76-178 1.26e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 61.40  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  76 PKKVGvdltfdDLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKI-- 153
Cdd:PLN00113  229 PYEIG------GLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIpe 302
                          90       100
                  ....*....|....*....|....*.
gi 1740152963 154 -LDGLGNISEIALQNNRLVGQIPLSL 178
Cdd:PLN00113  303 lVIQLQNLEILHLFSNNFTGKIPVAL 328
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
87-174 1.62e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.94  E-value: 1.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  87 DLAK---IKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDG---LGNI 160
Cdd:PLN00113  351 NLGKhnnLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGELPSEftkLPLV 430
                          90
                  ....*....|....
gi 1740152963 161 SEIALQNNRLVGQI 174
Cdd:PLN00113  431 YFLDISNNNLQGRI 444
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
85-228 3.33e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 56.78  E-value: 3.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  85 FDDLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGElTNLSELRLDYNQFTGKILDGLGNISEIA 164
Cdd:PLN00113  424 FTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGS-KRLENLDLSRNQFSGAVPRKLGSLSELM 502
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1740152963 165 ---LQNNRLVGQIP--LSLYENRTgenEVNVSGNQVT--INSKQSEPSVYSAYTFvypsSTPEYSGHIKAN 228
Cdd:PLN00113  503 qlkLSENKLSGEIPdeLSSCKKLV---SLDLSHNQLSgqIPASFSEMPVLSQLDL----SQNQLSGEIPKN 566
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
83-178 1.04e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 55.24  E-value: 1.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  83 LTFDDLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELT-NLSELRLDYNQFTGKILDG-LGNI 160
Cdd:PLN00113   63 ITCNNSSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPRGsIPNL 142
                          90
                  ....*....|....*...
gi 1740152963 161 SEIALQNNRLVGQIPLSL 178
Cdd:PLN00113  143 ETLDLSNNMLSGEIPNDI 160
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
88-175 1.17e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.69  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  88 LAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQFTGKILDGLG---NISEIA 164
Cdd:PLN00113  331 LPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEGEIPKSLGacrSLRRVR 410
                          90
                  ....*....|.
gi 1740152963 165 LQNNRLVGQIP 175
Cdd:PLN00113  411 LQDNSFSGELP 421
PLN03150 PLN03150
hypothetical protein; Provisional
80-134 3.43e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.12  E-value: 3.43e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1740152963  80 GVDLTFDDLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNKLSGEIPAELG 134
Cdd:PLN03150  457 NIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALG 511
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
21-196 8.65e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 45.31  E-value: 8.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  21 NPLSGLASKIETTKLKSTMDTNQQVNLKNNATDIVTSEDLGGQTWLINEVNRQLAPKKVGVDLTFDDLAKIKIISLSNKS 100
Cdd:COG4886     4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963 101 LTGEVPPEIKNLVSLEKLLLYSNKlsgeipaELGELTNLSELRLDYNQFT--GKILDGLGNISEIALQNNRLvGQIPLSL 178
Cdd:COG4886    84 LLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTdlPEELANLTNLKELDLSNNQL-TDLPEPL 155
                         170
                  ....*....|....*...
gi 1740152963 179 yENRTGENEVNVSGNQVT 196
Cdd:COG4886   156 -GNLTNLKSLDLSNNQLT 172
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
88-170 1.53e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.54  E-value: 1.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  88 LAKIKIISLSNKSLTgevppEIKNL---VSLEKLLLYSNKLSgEIPAeLGELTNLSELRLDYNQFTgKI--LDGLGNISE 162
Cdd:cd21340     1 LKRITHLYLNDKNIT-----KIDNLslcKNLKVLYLYDNKIT-KIEN-LEFLTNLTHLYLQNNQIE-KIenLENLVNLKK 72

                  ....*...
gi 1740152963 163 IALQNNRL 170
Cdd:cd21340    73 LYLGGNRI 80
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
509-543 1.63e-03

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 37.53  E-value: 1.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1740152963 509 DDVEVEGTVDTTKAGVYPVTYS---FAGESVTINVTVK 543
Cdd:pfam16403  33 DKVKVTGSVDTSKPGTYTLTYTvtdSDGNSATVTRTVT 70
LRR_8 pfam13855
Leucine rich repeat;
90-149 4.47e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 4.47e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1740152963  90 KIKIISLSNKSLTGeVPPEI-KNLVSLEKLLLYSNKLSGEIPAELGELTNLSELRLDYNQF 149
Cdd:pfam13855   2 NLRSLDLSNNRLTS-LDDGAfKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
45-196 8.17e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.15  E-value: 8.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740152963  45 VNLKNNATDIVTSEDLGGQTWLINEVNRQLAPKKVGVDLTFDDLAKIKIISLSNKSLTGEVPPEIKNLVSLEKLLLYSNK 124
Cdd:COG4886     1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1740152963 125 LSGE---IPAELGELTNLSELRLDYNQFtgkiLDGLGNISEIALQNNRLVgQIPLSLYENrTGENEVNVSGNQVT 196
Cdd:COG4886    81 LLSLlllGLTDLGDLTNLTELDLSGNEE----LSNLTNLESLDLSGNQLT-DLPEELANL-TNLKELDLSNNQLT 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH