|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
25-442 |
0e+00 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 528.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 25 VIPASQHNLRRERISKNAVNVVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSATPEQVRATFRNARLIGRRFKLVH 104
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 105 VHFGREIIEVATFRASHaddaetglaqgdeKSRQSESGRLLRDNVYGSFEDDAQRRDFTINALYYDVSSGHIHDYANGMH 184
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGH-------------KSSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGME 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 185 DIRERQIRLIGDPQQRYQEDPVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPAARLFDESLKLLMSGQGVKTFDL 264
Cdd:TIGR01942 148 DLKNRRLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRM 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 265 LHYYYLFEPLFPATEEAIEQNPDYSLALIRQALAN-TDDRIREGRPVTPAFLFAALLWPALAPRIKALEDQGVPTIPAQQ 343
Cdd:TIGR01942 228 LCGYQLLEPLFPSVAYALRESPKFESAFTVQALVNdTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQGVMPYPAVF 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 344 QAAQDLITEQCQHIAIPKRFSVPLREIWDMQPRLERRSGRRADQLLEHPRFRAAYDFLLLRESAGEDTEGLGRWWTRYQE 423
Cdd:TIGR01942 308 DAIRDFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVCGRENAVLGEWWTPYQL 387
|
410
....*....|....*....
gi 1740874730 424 VGEDQRRKMIAElGDKATG 442
Cdd:TIGR01942 388 ASEEERTEMTRS-AARHEG 405
|
|
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
3-438 |
1.19e-166 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 477.71 E-value: 1.19e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 3 RKLLKKLPTPFGRAAHRRTTpSVIPASQHNLRRERISKNAVNVVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSAT 82
Cdd:PRK11623 17 RKVLSREESEAEQAVARPQM-TVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNAT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 83 PEQVRATFRNARLIGRRFKLVHVHFGREIIEVATFRASHADDAETglaqgDEKSRQSESGRLLRDNVYGSFEDDAQRRDF 162
Cdd:PRK11623 96 PEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESD-----RNTSQRGQNGMLLRDNIFGSIEEDAQRRDF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 163 TINALYYDVSSGHIHDYANGMHDIRERQIRLIGDPQQRYQEDPVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPA 242
Cdd:PRK11623 171 TINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLNDIPP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 243 ARLFDESLKLLMSGQGVKTFDLLHYYYLFEPLFPATEEAIEQNPDYSLA-LIRQALANTDDRIREGRPVTPAFLFAALLW 321
Cdd:PRK11623 251 ARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMErIIEQVLKNTDTRIHNDMRVNPAFLFAAMFW 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 322 -PALAPRIKALEDQGVPTIPAQQQAAQDLITEQCQHIAIPKRFSVPLREIWDMQPRLERRSGRRADQLLEHPRFRAAYDF 400
Cdd:PRK11623 331 yPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDL 410
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1740874730 401 LLLRESAGEDTE--GLGRWWTRYQEVGEDQRRKMIAELGD 438
Cdd:PRK11623 411 LALRAEVENNAElqRLAQWWGEFQVSAPPQQKGMLNELDD 450
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
37-423 |
2.68e-116 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 346.42 E-value: 2.68e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 37 RISKNAVNVVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSATPEQVRATFR---NARLIGRRFKLVHVHFGREIIE 113
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 114 VATFRASHADdaetglaqgdeksrqsESGRLlRDNVYG-SFEDDAQRRDFTINALYYDVSSGHIHDYANGMHDIRERQIR 192
Cdd:COG0617 81 VATARTERYY----------------GDGRR-PFVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 193 LIGDPQQRYQEDPVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPAARLFDESLKLLMSGQGVKTFDLLHYYYLFE 272
Cdd:COG0617 144 TVGDPEERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 273 PLfpateeaieqnpdyslalirqalantddriregrpvtpAFLFAALLWPALAPRIKAledQGVPTIPAQQQAAQDLITE 352
Cdd:COG0617 224 VL--------------------------------------ALRLAALLHDLGKPATRE---DGLPTFHGHEEAGAELAEA 262
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1740874730 353 QCQHIAIPKRFSVPLREIWDMQPRLERRSGRRAD---QLLEHpRFRAAYDFLLLRESAGEDTEGLGRWWTRYQE 423
Cdd:COG0617 263 LLKRLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQERLAELLEA 335
|
|
| PolyA_pol_arg_C |
pfam12626 |
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is ... |
334-440 |
1.11e-49 |
|
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is arginine-rich and is necessary for full functioning of the enzyme.
Pssm-ID: 463647 [Multi-domain] Cd Length: 116 Bit Score: 165.07 E-value: 1.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 334 QGVPTIPAQQQAAQDLITEQCQHIAIPKRFSVPLREIWDMQPRLERRSGRRADQLLEHPRFRAAYDFLLLRESAGEDTEG 413
Cdd:pfam12626 1 QGLPPYDALQLAADEVLDEQCQRVAIPRRFTAPMREIWLLQPRLEKRQGKRPFRLLEHPRFRAAYDFLLLRAESGEVLQE 80
|
90 100
....*....|....*....|....*..
gi 1740874730 414 LGRWWTRYQEVGEDQRRKMIAELGDKA 440
Cdd:pfam12626 81 LAEWWTRFQEADEAEREAMIAELGADA 107
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
39-188 |
4.03e-35 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 127.32 E-value: 4.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 39 SKNAVNVVERLQQA-GYQAFVVGGCVRDSLLDMTPKDFDVATSA-TPEQVRATFR--NARLIGR--RFKLVHVHFGREII 112
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1740874730 113 EVATFRashaddaetglaqgdeKSRQSESGRLLRDNVYGSfEDDAQRRDFTINALYYDVSSGHIHDYANGMHDIRE 188
Cdd:cd05398 81 DVATLR----------------TETYTDPGRRPPVVGFTI-EEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
25-442 |
0e+00 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 528.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 25 VIPASQHNLRRERISKNAVNVVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSATPEQVRATFRNARLIGRRFKLVH 104
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 105 VHFGREIIEVATFRASHaddaetglaqgdeKSRQSESGRLLRDNVYGSFEDDAQRRDFTINALYYDVSSGHIHDYANGMH 184
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGH-------------KSSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGME 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 185 DIRERQIRLIGDPQQRYQEDPVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPAARLFDESLKLLMSGQGVKTFDL 264
Cdd:TIGR01942 148 DLKNRRLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRM 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 265 LHYYYLFEPLFPATEEAIEQNPDYSLALIRQALAN-TDDRIREGRPVTPAFLFAALLWPALAPRIKALEDQGVPTIPAQQ 343
Cdd:TIGR01942 228 LCGYQLLEPLFPSVAYALRESPKFESAFTVQALVNdTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQGVMPYPAVF 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 344 QAAQDLITEQCQHIAIPKRFSVPLREIWDMQPRLERRSGRRADQLLEHPRFRAAYDFLLLRESAGEDTEGLGRWWTRYQE 423
Cdd:TIGR01942 308 DAIRDFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVCGRENAVLGEWWTPYQL 387
|
410
....*....|....*....
gi 1740874730 424 VGEDQRRKMIAElGDKATG 442
Cdd:TIGR01942 388 ASEEERTEMTRS-AARHEG 405
|
|
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
3-438 |
1.19e-166 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 477.71 E-value: 1.19e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 3 RKLLKKLPTPFGRAAHRRTTpSVIPASQHNLRRERISKNAVNVVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSAT 82
Cdd:PRK11623 17 RKVLSREESEAEQAVARPQM-TVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNAT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 83 PEQVRATFRNARLIGRRFKLVHVHFGREIIEVATFRASHADDAETglaqgDEKSRQSESGRLLRDNVYGSFEDDAQRRDF 162
Cdd:PRK11623 96 PEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESD-----RNTSQRGQNGMLLRDNIFGSIEEDAQRRDF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 163 TINALYYDVSSGHIHDYANGMHDIRERQIRLIGDPQQRYQEDPVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPA 242
Cdd:PRK11623 171 TINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLNDIPP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 243 ARLFDESLKLLMSGQGVKTFDLLHYYYLFEPLFPATEEAIEQNPDYSLA-LIRQALANTDDRIREGRPVTPAFLFAALLW 321
Cdd:PRK11623 251 ARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMErIIEQVLKNTDTRIHNDMRVNPAFLFAAMFW 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 322 -PALAPRIKALEDQGVPTIPAQQQAAQDLITEQCQHIAIPKRFSVPLREIWDMQPRLERRSGRRADQLLEHPRFRAAYDF 400
Cdd:PRK11623 331 yPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDL 410
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1740874730 401 LLLRESAGEDTE--GLGRWWTRYQEVGEDQRRKMIAELGD 438
Cdd:PRK11623 411 LALRAEVENNAElqRLAQWWGEFQVSAPPQQKGMLNELDD 450
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
37-423 |
2.68e-116 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 346.42 E-value: 2.68e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 37 RISKNAVNVVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSATPEQVRATFR---NARLIGRRFKLVHVHFGREIIE 113
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 114 VATFRASHADdaetglaqgdeksrqsESGRLlRDNVYG-SFEDDAQRRDFTINALYYDVSSGHIHDYANGMHDIRERQIR 192
Cdd:COG0617 81 VATARTERYY----------------GDGRR-PFVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 193 LIGDPQQRYQEDPVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPAARLFDESLKLLMSGQGVKTFDLLHYYYLFE 272
Cdd:COG0617 144 TVGDPEERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLE 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 273 PLfpateeaieqnpdyslalirqalantddriregrpvtpAFLFAALLWPALAPRIKAledQGVPTIPAQQQAAQDLITE 352
Cdd:COG0617 224 VL--------------------------------------ALRLAALLHDLGKPATRE---DGLPTFHGHEEAGAELAEA 262
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1740874730 353 QCQHIAIPKRFSVPLREIWDMQPRLERRSGRRAD---QLLEHpRFRAAYDFLLLRESAGEDTEGLGRWWTRYQE 423
Cdd:COG0617 263 LLKRLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQERLAELLEA 335
|
|
| PRK13299 |
PRK13299 |
tRNA CCA-pyrophosphorylase; Provisional |
45-298 |
3.35e-53 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237339 [Multi-domain] Cd Length: 394 Bit Score: 183.12 E-value: 3.35e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 45 VVERLQQAGYQAFVVGGCVRDSLLDMTPKDFDVATSATPEQVRATFRNARLIGRRFKLVHVHFGREIIEVATFRAshadd 124
Cdd:PRK13299 12 ILEKIKEAGFEAYFVGGSVRDYLLGRPIHDVDIATSAYPEEVKAIFPRTVDVGIEHGTVLVLENGEEYEVTTFRT----- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 125 aETGLaqgdEKSRQSESGRLLRdnvygSFEDDAQRRDFTINALYYDVSsGHIHDYANGMHDIRERQIRLIGDPQQRYQED 204
Cdd:PRK13299 87 -ESEY----VDYRRPSEVTFVR-----SLEEDLKRRDFTINAIAMDEN-GEIIDLFDGLEDLKNRLIRAVGNAEERFQED 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 205 PVRMLRAVRFAAKLDFEIEQHSAAPIPDMADLLFDIPAARLFDESLKLLMsGQGVKT-FDLLH----YYYLfePLFPATE 279
Cdd:PRK13299 156 ALRMMRAVRFASQLGFDLETETFEAMKTQAPLLEKISVERIFVEFEKLLL-GPFWRKgLKLLIetglYNYL--PGLKGKE 232
|
250 260
....*....|....*....|..
gi 1740874730 280 EAIE---QNPDYSLALIRQALA 298
Cdd:PRK13299 233 ENLLkltQLLWFSFETSEQAWA 254
|
|
| PolyA_pol_arg_C |
pfam12626 |
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is ... |
334-440 |
1.11e-49 |
|
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is arginine-rich and is necessary for full functioning of the enzyme.
Pssm-ID: 463647 [Multi-domain] Cd Length: 116 Bit Score: 165.07 E-value: 1.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 334 QGVPTIPAQQQAAQDLITEQCQHIAIPKRFSVPLREIWDMQPRLERRSGRRADQLLEHPRFRAAYDFLLLRESAGEDTEG 413
Cdd:pfam12626 1 QGLPPYDALQLAADEVLDEQCQRVAIPRRFTAPMREIWLLQPRLEKRQGKRPFRLLEHPRFRAAYDFLLLRAESGEVLQE 80
|
90 100
....*....|....*....|....*..
gi 1740874730 414 LGRWWTRYQEVGEDQRRKMIAELGDKA 440
Cdd:pfam12626 81 LAEWWTRFQEADEAEREAMIAELGADA 107
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
56-192 |
1.22e-41 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 144.34 E-value: 1.22e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 56 AFVVGGCVRDSLLDMTPKDFDVATSATPEQVRATFRNARLI----GRRFKLVHVHFGREIIEVATFRASHADDaetglaq 131
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFDES------- 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1740874730 132 gdeksrqseSGRLLRDNVY-GSFEDDAQRRDFTINALYYDVSSGHIHDYANGMHDIRERQIR 192
Cdd:pfam01743 74 ---------DFRNPRSEEYtGTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
39-188 |
4.03e-35 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 127.32 E-value: 4.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 39 SKNAVNVVERLQQA-GYQAFVVGGCVRDSLLDMTPKDFDVATSA-TPEQVRATFR--NARLIGR--RFKLVHVHFGREII 112
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1740874730 113 EVATFRashaddaetglaqgdeKSRQSESGRLLRDNVYGSfEDDAQRRDFTINALYYDVSSGHIHDYANGMHDIRE 188
Cdd:cd05398 81 DVATLR----------------TETYTDPGRRPPVVGFTI-EEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| PRK13298 |
PRK13298 |
tRNA CCA-pyrophosphorylase; Provisional |
57-218 |
2.43e-17 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237338 [Multi-domain] Cd Length: 417 Bit Score: 83.63 E-value: 2.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 57 FVVGGCVRDSLLDMTPKDFD-VATSATPEQVRAtfRNARLIGRRFKlVHVHfgreiievatfRASHAddaETGLAQGDEK 135
Cdd:PRK13298 4 YLVGGAVRDSLLNLPVKDKDwVVVGGTPKILLS--INFQQVGKDFP-VFLH-----------PETHE---EYALARTERK 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 136 SRQSESGRLLRDNVYGSFEDDAQRRDFTINALYYDvSSGHIHDYANGMHDIRERQIRLIgdpQQRYQEDPVRMLRAVRFA 215
Cdd:PRK13298 67 SGVGYTGFITDTSSDVTLEEDLIRRDLTINAIAQD-ENGNYIDPFQGKKDIQLRLLRHV---SESFIEDPLRVLRVARFA 142
|
...
gi 1740874730 216 AKL 218
Cdd:PRK13298 143 ALL 145
|
|
| PolyA_pol_RNAbd |
pfam12627 |
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA ... |
219-282 |
9.24e-17 |
|
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA and SrmB binding motifs on polymerase A.
Pssm-ID: 463648 [Multi-domain] Cd Length: 64 Bit Score: 74.44 E-value: 9.24e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1740874730 219 DFEIEQHSAAPIPDMADLLFDIPAARLFDESLKLLMSGQGVKTFDLLHYYYLFEPLFPATEEAI 282
Cdd:pfam12627 1 GFTIEPETREAIRKLAPLLKKISPERIFEELLKLLLSGHPERGLELLRETGLLEYLFPELAAAL 64
|
|
| cca |
PRK10885 |
multifunctional CCA addition/repair protein; |
55-222 |
1.25e-14 |
|
multifunctional CCA addition/repair protein;
Pssm-ID: 182810 [Multi-domain] Cd Length: 409 Bit Score: 75.28 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 55 QAFVVGGCVRDSLLDMTPKDFD-VATSATPEQVRAtfRNARLIGRRFKL-VHVHFGREiievatfrasHAddaetgLAQG 132
Cdd:PRK10885 2 KIYLVGGAVRDALLGLPVKDRDwVVVGATPEEMLA--QGYQQVGKDFPVfLHPKTHEE----------YA------LART 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 133 DEKSRQSesgrllrdnvYGSF----------EDDAQRRDFTINALYYDvSSGHIHDYANGMHDIRERQIRLIGDPqqrYQ 202
Cdd:PRK10885 64 ERKSGRG----------YTGFtcyaapdvtlEEDLIRRDLTINAMAQD-DDGELIDPYGGQRDLEARLLRHVSPA---FA 129
|
170 180
....*....|....*....|...
gi 1740874730 203 EDPVRMLRAVRFAAK---LDFEI 222
Cdd:PRK10885 130 EDPLRVLRVARFAARfahLGFRI 152
|
|
| PRK13297 |
PRK13297 |
tRNA CCA-pyrophosphorylase; Provisional |
52-222 |
3.65e-14 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 139469 [Multi-domain] Cd Length: 364 Bit Score: 73.49 E-value: 3.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 52 AGYQAFVVGGCVRDSLLDMTPKDFD-VATSATPEQVratfrnARligRRFKLVHVHFgreiievATFRASHADDaETGLA 130
Cdd:PRK13297 10 AGLQVYIVGGAVRDALLGLPAGDRDwVVVGATPEDM------AR---RGFIPVGGDF-------PVFLHPRTKE-EYALA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 131 QGDEKSRQSESGRLLRDNVYGSFEDDAQRRDFTINALYyDVSSGHIHDYANGMHDIRERQIRLIGDPqqrYQEDPVRMLR 210
Cdd:PRK13297 73 RTERKSGRGYKGFTFYTGADVTLEQDLQRRDLTVNAIA-RTPQGELVDPLDGVADVRARVLRHVGEA---FAEDPVRILR 148
|
170
....*....|...
gi 1740874730 211 AVRFAAKL-DFEI 222
Cdd:PRK13297 149 LGRFAARFgDFSI 161
|
|
| PRK13296 |
PRK13296 |
CCA tRNA nucleotidyltransferase; |
57-218 |
1.18e-12 |
|
CCA tRNA nucleotidyltransferase;
Pssm-ID: 106256 [Multi-domain] Cd Length: 360 Bit Score: 68.86 E-value: 1.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 57 FVVGGCVRDSLLDMTPKDFD-VATSATPEQ-VRATFRNarlIGRRFKlVHVHfgreiievatfrasHADDAETGLAQGDE 134
Cdd:PRK13296 4 YLVGGAVRDMLLGITPKDKDwVVVGATEDEmLANGFIK---IAANFP-VFIH--------------PQTKQEYALARSEK 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1740874730 135 KSRQSESGRLLRDNVYGSFEDDAQRRDFTINALYYDvSSGHIHDYANGMHDIRERQIRligDPQQRYQEDPVRMLRAVRF 214
Cdd:PRK13296 66 KTASGYHGFEVNFSKYITLEDDLKRRDLTINSIAID-QNNKVIDPFNGQADLQNRILR---HTSIAFIEDPLRVVRLARF 141
|
....
gi 1740874730 215 AAKL 218
Cdd:PRK13296 142 KAQL 145
|
|
| |
