|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
4-882 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1291.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 4 LSSAEVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRT----NDIENVG 79
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTggkhNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 80 HTARHHTLFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVYPNDDQAKDIWLHKVGLPKDHLYE--EPDN 157
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLT--EVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRlgKKDN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 158 FWDIGE-GPSGPDSEIFYDRGEEFndPDEAENYPGGENERYLEIWNLVFSQFNHLPgltdNKDYPELPTKNIDTGMGLER 236
Cdd:COG0013 160 FWEMGDtGPCGPCSEIFYDRGPEY--GGGPPGSPGEDGDRYIEIWNLVFMQFNRDE----DGTLTPLPKKNIDTGMGLER 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 237 VVSVFQHAKTNFETDLFLPLIHKTEDISGQfKYGEDDTKDISFKVIADHIRAVTFAIGDGALPSNEGRGYIIRRLLRRAV 316
Cdd:COG0013 234 IAAVLQGVHSNYETDLFRPLIEAAAELTGV-KYGADEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRRILRRAV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 317 LHGRKLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKKG-IIDGAIA 395
Cdd:COG0013 313 RHGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKAAGGkVLSGEDA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 396 FKLYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSARSNKASMGVQNEL--LTGLKTPSQYVGWSELTVEqT 473
Cdd:COG0013 393 FKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDGVWreLLEEGGPTEFVGYDTLEAE-A 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 474 ELVNLIVDNKLVEEANAGQ-VQAIFAKTPFYAEMGGQVADLGMIydESGQAVAKVTDVQNAPNGQHLHTLSIIA-PLFVG 551
Cdd:COG0013 472 KVLALVKDGELVDSAKAGEeVEVVLDRTPFYAESGGQVGDTGTI--EGDGGVFEVTDTQKPPGGLIVHIGKVEEgELKVG 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 552 KQYKLDVDRPYHVAVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRYDFTYNGAVPSEKLQEVEDIINQKIIDNLP 631
Cdd:COG0013 550 DTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLP 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 632 ISWIETDIESAKKLGAVAVFTEKYGEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRIEAVTGSGAMA 711
Cdd:COG0013 630 VETREMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALE 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 712 LFKLHDSWLAKAAEQVKAPqLSEINDKISGLQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIATEMAVESMD 791
Cdd:COG0013 710 YLREQEALLKELAELLKAP-PEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAK 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 792 VLRSTADTWKQSTPSDVLVLAANLGEKVNLLVAVAPEAVKKGIKAGDLVKSIAPAIGGGGGGRPDMAQAGGKNPAGIADA 871
Cdd:COG0013 789 DLRDLADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKLDEA 868
|
890
....*....|.
gi 1751980632 872 FKQAADWLQEK 882
Cdd:COG0013 869 LAAVKEWLAEK 879
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-862 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 911.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 8 EVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRTNDIENVGHTARHHTL 87
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRLNDLENVGRTARHHTL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 88 FEMMGNFSIGDYFKEEAIPWAWELLTSPewFGMDPDKLYVTVYPNDDQAKDIWLhKVGLPKDHLYE--EPDNFWDIGEGP 165
Cdd:TIGR00344 81 FEMLGNFSFGDYFKEEAIAFAWELLTEV--LGLDKERLYVTVYEDDEEAYKIWE-KIGIPADRIIKcdAKDNFWDMGDGP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 166 SGPDSEIFYDRgeefnDPDEaENYPGGENERYLEIWNLVFSQFNHLPgltdNKDYPELPTKNIDTGMGLERVVSVFQHAK 245
Cdd:TIGR00344 158 CGPCTEIYYDF-----VGGK-PGEPLEENDRYLEVWNLVFMQFNRDP----DGNYTPLPKKNIDTGMGLERFVAVLQGVP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 246 TNFETDLFLPLIHKTEDISG----QFKYGEDDTKDI----SFKVIADHIRAVTFAIGDGALPSNEGRGYIIRRLLRRAVL 317
Cdd:TIGR00344 228 TNYDTDIFLPLIEKIEEITGvkydSNNAGIMDEKRVedlrSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLIRRALR 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 318 HGRKLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKkgIIDGAIAFK 397
Cdd:TIGR00344 308 HGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKK--ELDGEDAFK 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 398 LYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSArsnkASMGVQNELLTGLKTPSQYVGWSELTVEqTELVN 477
Cdd:TIGR00344 386 LYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQN----SQFQEQEIALVNVYPATEFLGYDDLEFE-AKVIG 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 478 LIVDNKLVEEANAGQ-VQAIFAKTPFYAEMGGQVADLGMIYDEsgQAVAKVTDVQNaPNGQHLHTLSI-IAPLFVGKQYK 555
Cdd:TIGR00344 461 LFDDGYLVEQALAGQsVYVILDQTPFYAESGGQIGDTGYLIAN--DGKFRVVDVQK-PNGVVFHFGEVeGGSLKVGDKVI 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 556 LDVDRPYHVAVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRYDFTYNGAVPSEKLQEVEDIINQKIIDNLPISWI 635
Cdd:TIGR00344 538 AVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVI 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 636 ETDIESAKKLGAVAVFTEKY--GEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRIEAVTGSGAMALF 713
Cdd:TIGR00344 618 FMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYL 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 714 KLHDSWLAKAAEQVKAPqLSEINDKISGLQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIATEMAVESMDVL 793
Cdd:TIGR00344 698 NEQEDKLKELADILKVT-PNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSL 776
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1751980632 794 RSTADTWKQSTPSDVLVLAANLGEKVNLLVAVAPEAVKKGIKAGDLVKSIAPAIGGGGGGRPDMAQAGG 862
Cdd:TIGR00344 777 KTMADRLKSKLGSAIYVLASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
1-875 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 789.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 1 MKELSSAEVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENH-----RITNAQKSIRT--- 72
Cdd:PLN02900 8 EKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPlrklpRATNTQKCIRAggk 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 73 -NDIENVGHTARHHTLFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVY------PNDDQAKDIWLhKVg 145
Cdd:PLN02900 88 hNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLT--KVYGLPADRLYATYFggdekqAPDDEARAIWL-DY- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 146 LPKDHL--YEEPDNFWDIGE-GPSGPDSEIFYDR-GEEfnDPDEAENypgGENERYLEIWNLVFSQFNHlpglTDNKDYP 221
Cdd:PLN02900 164 LPEERVlpFGCKDNFWEMGDtGPCGPCSEIHYDRiGER--DAADLVN---NDDPRFIEIWNLVFIQFNR----EADGSLK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 222 ELPTKNIDTGMGLERVVSVFQHAKTNFETDLFLPLIHKTEDISGQFKYG------EDDTKDISFKVIADHIRAVTFAIGD 295
Cdd:PLN02900 235 PLPAKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAgkvgaeDDDRVDMAYRVVADHIRTLSFAIAD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 296 GALPSNEGRGYIIRRLLRRAVLHGR-KLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLS 374
Cdd:PLN02900 315 GVVPSNEGRGYVLRRLLRRAVRYGRlLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 375 LLDDVIEQAKSKKG-IIDGAIAFKLYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSARsnKASMGVQNEL- 452
Cdd:PLN02900 395 KFKKALAAAKANGGpVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAH--LKAGGGAIELa 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 453 --------LTGLKTPSQYVGWSELTVEQTELVNLIVDNKLVEEANAG-QVQAIFAKTPFYAEMGGQVADLGMIYDESGQA 523
Cdd:PLN02900 473 aeatswlqKQGVAATDDFLKYDWLSDHEAVVKAILTGGGFVESVSEGdEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 524 VaKVTDVQNApNGQHLHTLSIIA-PLFVGKQYKLDVDRPYHVAVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRY 602
Cdd:PLN02900 553 V-EVSDVQKA-GGFVLHIGTVTEgSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 603 DFTYNGAVPSEKLQEVEDIINQKIIDNLPISWIETDIESAKKL-GAVAVFTEKYGEKVRVVSIGD-YNAEFDGGTHANST 680
Cdd:PLN02900 631 DFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRInGLRAVFGEKYPDPVRVVSVGGvYSMELCGGTHVSNT 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 681 AELGMFKIVGEQGTGAGVRRIEAVTGSGAMALFKLHDSWLAKAAEQVK-----------------------APQLSEIND 737
Cdd:PLN02900 711 AEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKvegsdlekkvaslksrvdaavipAAKKEEIRA 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 738 KISGLQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIAT-EMAVESmDVLRSTADTW--KQSTPSDVLVLAAN 814
Cdd:PLN02900 791 RVSALQKELRAAQKEAAALRAKLAVAKATELASKALSAGKSVLVARlDVGVDA-AALKEAAEKViaKLGDPAAVVLSSDE 869
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1751980632 815 LGEKVNLLVAVAPEAVKKGIKAGDLVKSIAPAIGGGGGGRPDMAQAGGKNPAGIADAFKQA 875
Cdd:PLN02900 870 EKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKA 930
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-562 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 669.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 8 EVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVV-PENHRITNAQKSIRTNDIENVGHTARHHT 86
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAkPPYNRATNSQKCIRAGDLENVGRTGRHHT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 87 LFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVYPNDDQAKDIWLHKVGLPKDHL--YEEPDNFWDIGE- 163
Cdd:pfam01411 81 FFEMLGNFSFGDYFKEEAIEYAWELLT--KELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERIlrFGDKDNFWEMGDt 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 164 GPSGPDSEIFYDRGEEFNDPDEAENyPGGENERYLEIWNLVFSQFNHlpglTDNKDYPELPTKNIDTGMGLERVVSVFQH 243
Cdd:pfam01411 159 GPCGPCSEIDYDRGEEIGGWDSGGT-PTADDDRFLEIWNLVFMQFNR----ENDGTLKPLPKKSIDTGMGLERLVAVLQD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 244 AKTNFETDLFLPLIHKTEDISGQfKYGEDDTKDISFKVIADHIRAVTFAIGDGALPSNEGRGYIIRRLLRRAVLHGRKLG 323
Cdd:pfam01411 234 VRSNYDTDVFIPVIELIEEISGA-RYYTVDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRILRRAVRHAKKLG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 324 ISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKKGIIDGAIAFKLYDTYG 403
Cdd:pfam01411 313 LKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKGKKTLPGEDAFKLYDTYG 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 404 FPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSARSNKASMgVQNELLTGLKTPSQYVGWSELTVEqTELVNLIVDNK 483
Cdd:pfam01411 393 FPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGEK-LDVSALKELPATTEFLGYDDLESE-AKILALPKDGE 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 484 LVEEANAGQ-VQAIFAKTPFYAEMGGQVADLGMIYDESGqaVAKVTDVQnAPNGQHLHTLSIIAPLF-VGKQYKLDVDRP 561
Cdd:pfam01411 471 FVAEVLAGQeGGVILDRTPFYAESGGQIGDTGYIIGDGG--EFRVTDVQ-KYGGVVVHKGKLESGKLkVGDKVIAVIDED 547
|
.
gi 1751980632 562 Y 562
Cdd:pfam01411 548 R 548
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-243 |
7.46e-111 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 339.34 E-value: 7.46e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 6 SAEVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRTNDIENVGHTARHH 85
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDNVGKTGRHH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 86 TLFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVYPNDDQAKDIWLHKVGLPKDHLYE--EPDNFWDIG- 162
Cdd:cd00673 81 TFFEMLGNFSFGDYFKEEAIAFAWELLT--EVLGLPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERigFKDNFWEMGg 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 163 EGPSGPDSEIFYDRGEEFNdpdeAENYPGGENERYLEIWNLVFSQFNHlpglTDNKDYPELPTKNIDTGMGLERVVSVFQ 242
Cdd:cd00673 159 NGPCGPCSEIFYDRGEERD----AASLPNEDDDRYLEIWNLVFMQYNR----DADGTYRPLPKKIVDTGMGLERLVWVLQ 230
|
.
gi 1751980632 243 H 243
Cdd:cd00673 231 G 231
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
659-701 |
1.19e-14 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 68.56 E-value: 1.19e-14
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1751980632 659 VRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRI 701
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
4-882 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1291.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 4 LSSAEVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRT----NDIENVG 79
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKPPYPRATTSQKCVRTggkhNDLENVG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 80 HTARHHTLFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVYPNDDQAKDIWLHKVGLPKDHLYE--EPDN 157
Cdd:COG0013 82 YTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLT--EVLGLPKERLWVTVYEDDDEAYDIWKKEIGVPEERIIRlgKKDN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 158 FWDIGE-GPSGPDSEIFYDRGEEFndPDEAENYPGGENERYLEIWNLVFSQFNHLPgltdNKDYPELPTKNIDTGMGLER 236
Cdd:COG0013 160 FWEMGDtGPCGPCSEIFYDRGPEY--GGGPPGSPGEDGDRYIEIWNLVFMQFNRDE----DGTLTPLPKKNIDTGMGLER 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 237 VVSVFQHAKTNFETDLFLPLIHKTEDISGQfKYGEDDTKDISFKVIADHIRAVTFAIGDGALPSNEGRGYIIRRLLRRAV 316
Cdd:COG0013 234 IAAVLQGVHSNYETDLFRPLIEAAAELTGV-KYGADEEDDVSLRVIADHIRAVAFLIADGVLPSNEGRGYVLRRILRRAV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 317 LHGRKLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKKG-IIDGAIA 395
Cdd:COG0013 313 RHGRLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKLKAAGGkVLSGEDA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 396 FKLYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSARSNKASMGVQNEL--LTGLKTPSQYVGWSELTVEqT 473
Cdd:COG0013 393 FKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAMEEQRERARAAAKFSGDAAVDGVWreLLEEGGPTEFVGYDTLEAE-A 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 474 ELVNLIVDNKLVEEANAGQ-VQAIFAKTPFYAEMGGQVADLGMIydESGQAVAKVTDVQNAPNGQHLHTLSIIA-PLFVG 551
Cdd:COG0013 472 KVLALVKDGELVDSAKAGEeVEVVLDRTPFYAESGGQVGDTGTI--EGDGGVFEVTDTQKPPGGLIVHIGKVEEgELKVG 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 552 KQYKLDVDRPYHVAVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRYDFTYNGAVPSEKLQEVEDIINQKIIDNLP 631
Cdd:COG0013 550 DTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLP 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 632 ISWIETDIESAKKLGAVAVFTEKYGEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRIEAVTGSGAMA 711
Cdd:COG0013 630 VETREMPLDEAKALGAMALFGEKYGDEVRVVSIGDFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALE 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 712 LFKLHDSWLAKAAEQVKAPqLSEINDKISGLQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIATEMAVESMD 791
Cdd:COG0013 710 YLREQEALLKELAELLKAP-PEELPERVEALLEELKELEKELEQLKAKLASAAADDLLAQAEEIGGVKVLAARVEGVDAK 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 792 VLRSTADTWKQSTPSDVLVLAANLGEKVNLLVAVAPEAVKKGIKAGDLVKSIAPAIGGGGGGRPDMAQAGGKNPAGIADA 871
Cdd:COG0013 789 DLRDLADDLKDKLGSGVVVLASVADGKVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKLDEA 868
|
890
....*....|.
gi 1751980632 872 FKQAADWLQEK 882
Cdd:COG0013 869 LAAVKEWLAEK 879
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-862 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 911.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 8 EVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRTNDIENVGHTARHHTL 87
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSNRLTNAQPCIRLNDLENVGRTARHHTL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 88 FEMMGNFSIGDYFKEEAIPWAWELLTSPewFGMDPDKLYVTVYPNDDQAKDIWLhKVGLPKDHLYE--EPDNFWDIGEGP 165
Cdd:TIGR00344 81 FEMLGNFSFGDYFKEEAIAFAWELLTEV--LGLDKERLYVTVYEDDEEAYKIWE-KIGIPADRIIKcdAKDNFWDMGDGP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 166 SGPDSEIFYDRgeefnDPDEaENYPGGENERYLEIWNLVFSQFNHLPgltdNKDYPELPTKNIDTGMGLERVVSVFQHAK 245
Cdd:TIGR00344 158 CGPCTEIYYDF-----VGGK-PGEPLEENDRYLEVWNLVFMQFNRDP----DGNYTPLPKKNIDTGMGLERFVAVLQGVP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 246 TNFETDLFLPLIHKTEDISG----QFKYGEDDTKDI----SFKVIADHIRAVTFAIGDGALPSNEGRGYIIRRLLRRAVL 317
Cdd:TIGR00344 228 TNYDTDIFLPLIEKIEEITGvkydSNNAGIMDEKRVedlrSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRRLIRRALR 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 318 HGRKLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKkgIIDGAIAFK 397
Cdd:TIGR00344 308 HGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGKK--ELDGEDAFK 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 398 LYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSArsnkASMGVQNELLTGLKTPSQYVGWSELTVEqTELVN 477
Cdd:TIGR00344 386 LYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQN----SQFQEQEIALVNVYPATEFLGYDDLEFE-AKVIG 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 478 LIVDNKLVEEANAGQ-VQAIFAKTPFYAEMGGQVADLGMIYDEsgQAVAKVTDVQNaPNGQHLHTLSI-IAPLFVGKQYK 555
Cdd:TIGR00344 461 LFDDGYLVEQALAGQsVYVILDQTPFYAESGGQIGDTGYLIAN--DGKFRVVDVQK-PNGVVFHFGEVeGGSLKVGDKVI 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 556 LDVDRPYHVAVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRYDFTYNGAVPSEKLQEVEDIINQKIIDNLPISWI 635
Cdd:TIGR00344 538 AVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTREELEEIEDLANEQILANIPIKVI 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 636 ETDIESAKKLGAVAVFTEKY--GEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRIEAVTGSGAMALF 713
Cdd:TIGR00344 618 FMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGDFSVELCGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYL 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 714 KLHDSWLAKAAEQVKAPqLSEINDKISGLQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIATEMAVESMDVL 793
Cdd:TIGR00344 698 NEQEDKLKELADILKVT-PNELPKKVERFFEEWKALQKELESLKLKIADQKIDELKDKAETINGVKVLVEVVDAKDMKSL 776
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1751980632 794 RSTADTWKQSTPSDVLVLAANLGEKVNLLVAVAPEAVKKGIKAGDLVKSIAPAIGGGGGGRPDMAQAGG 862
Cdd:TIGR00344 777 KTMADRLKSKLGSAIYVLASFAEGKVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
1-875 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 789.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 1 MKELSSAEVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENH-----RITNAQKSIRT--- 72
Cdd:PLN02900 8 EKEWPGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPlrklpRATNTQKCIRAggk 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 73 -NDIENVGHTARHHTLFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVY------PNDDQAKDIWLhKVg 145
Cdd:PLN02900 88 hNDLDDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLT--KVYGLPADRLYATYFggdekqAPDDEARAIWL-DY- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 146 LPKDHL--YEEPDNFWDIGE-GPSGPDSEIFYDR-GEEfnDPDEAENypgGENERYLEIWNLVFSQFNHlpglTDNKDYP 221
Cdd:PLN02900 164 LPEERVlpFGCKDNFWEMGDtGPCGPCSEIHYDRiGER--DAADLVN---NDDPRFIEIWNLVFIQFNR----EADGSLK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 222 ELPTKNIDTGMGLERVVSVFQHAKTNFETDLFLPLIHKTEDISGQFKYG------EDDTKDISFKVIADHIRAVTFAIGD 295
Cdd:PLN02900 235 PLPAKHVDTGMGLERLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAgkvgaeDDDRVDMAYRVVADHIRTLSFAIAD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 296 GALPSNEGRGYIIRRLLRRAVLHGR-KLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLS 374
Cdd:PLN02900 315 GVVPSNEGRGYVLRRLLRRAVRYGRlLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 375 LLDDVIEQAKSKKG-IIDGAIAFKLYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSARsnKASMGVQNEL- 452
Cdd:PLN02900 395 KFKKALAAAKANGGpVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRAAH--LKAGGGAIELa 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 453 --------LTGLKTPSQYVGWSELTVEQTELVNLIVDNKLVEEANAG-QVQAIFAKTPFYAEMGGQVADLGMIYDESGQA 523
Cdd:PLN02900 473 aeatswlqKQGVAATDDFLKYDWLSDHEAVVKAILTGGGFVESVSEGdEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 524 VaKVTDVQNApNGQHLHTLSIIA-PLFVGKQYKLDVDRPYHVAVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRY 602
Cdd:PLN02900 553 V-EVSDVQKA-GGFVLHIGTVTEgSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRF 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 603 DFTYNGAVPSEKLQEVEDIINQKIIDNLPISWIETDIESAKKL-GAVAVFTEKYGEKVRVVSIGD-YNAEFDGGTHANST 680
Cdd:PLN02900 631 DFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRInGLRAVFGEKYPDPVRVVSVGGvYSMELCGGTHVSNT 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 681 AELGMFKIVGEQGTGAGVRRIEAVTGSGAMALFKLHDSWLAKAAEQVK-----------------------APQLSEIND 737
Cdd:PLN02900 711 AEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLERELDSALKvegsdlekkvaslksrvdaavipAAKKEEIRA 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 738 KISGLQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIAT-EMAVESmDVLRSTADTW--KQSTPSDVLVLAAN 814
Cdd:PLN02900 791 RVSALQKELRAAQKEAAALRAKLAVAKATELASKALSAGKSVLVARlDVGVDA-AALKEAAEKViaKLGDPAAVVLSSDE 869
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1751980632 815 LGEKVNLLVAVAPEAVKKGIKAGDLVKSIAPAIGGGGGGRPDMAQAGGKNPAGIADAFKQA 875
Cdd:PLN02900 870 EKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKA 930
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-562 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 669.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 8 EVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVV-PENHRITNAQKSIRTNDIENVGHTARHHT 86
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVAkPPYNRATNSQKCIRAGDLENVGRTGRHHT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 87 LFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVYPNDDQAKDIWLHKVGLPKDHL--YEEPDNFWDIGE- 163
Cdd:pfam01411 81 FFEMLGNFSFGDYFKEEAIEYAWELLT--KELGLPPERLYVTVFEWDDEAGPIWEKIVGGPEERIlrFGDKDNFWEMGDt 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 164 GPSGPDSEIFYDRGEEFNDPDEAENyPGGENERYLEIWNLVFSQFNHlpglTDNKDYPELPTKNIDTGMGLERVVSVFQH 243
Cdd:pfam01411 159 GPCGPCSEIDYDRGEEIGGWDSGGT-PTADDDRFLEIWNLVFMQFNR----ENDGTLKPLPKKSIDTGMGLERLVAVLQD 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 244 AKTNFETDLFLPLIHKTEDISGQfKYGEDDTKDISFKVIADHIRAVTFAIGDGALPSNEGRGYIIRRLLRRAVLHGRKLG 323
Cdd:pfam01411 234 VRSNYDTDVFIPVIELIEEISGA-RYYTVDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVLRRILRRAVRHAKKLG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 324 ISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKKGIIDGAIAFKLYDTYG 403
Cdd:pfam01411 313 LKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKGKKTLPGEDAFKLYDTYG 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 404 FPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSARSNKASMgVQNELLTGLKTPSQYVGWSELTVEqTELVNLIVDNK 483
Cdd:pfam01411 393 FPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEKGEK-LDVSALKELPATTEFLGYDDLESE-AKILALPKDGE 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 484 LVEEANAGQ-VQAIFAKTPFYAEMGGQVADLGMIYDESGqaVAKVTDVQnAPNGQHLHTLSIIAPLF-VGKQYKLDVDRP 561
Cdd:pfam01411 471 FVAEVLAGQeGGVILDRTPFYAESGGQIGDTGYIIGDGG--EFRVTDVQ-KYGGVVVHKGKLESGKLkVGDKVIAVIDED 547
|
.
gi 1751980632 562 Y 562
Cdd:pfam01411 548 R 548
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
8-707 |
0e+00 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 537.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 8 EVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRTNDIENVGhTARHHTL 87
Cdd:PRK01584 5 ELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGTRLVDVQKCLRTGDIDEVG-DLSHLTF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 88 FEMMGNFSIGDYFKEEAIPWAWELLTSPEWFGMDPDKLYVTVY------PNDDQAKDIWlHKVGLPKDHLYEEP--DNFW 159
Cdd:PRK01584 84 FEMLGNWSLGAYFKEESIKYSFEFLTSPDYLNIPKDKLYVTVFegdeeiPRDEETASVW-ESLGIPKDRIFYLSreHNWW 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 160 D-IGE-GPSGPDSEIFYDRGEefnDPDEAENYPGGENERYLEIWNLVFSQFNHLPgltdNKDYPELPTKNIDTGMGLERV 237
Cdd:PRK01584 163 GpVGEtGPCGPDTEIFVDTGK---PKCSVNCRPTCSCGKYFEIWNNVFMQYNKDE----DGNYEELKRKCVDTGMGIERT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 238 VSVFQHAKTNFETDLFLPLIHKTEDISGQfKYGEDDTKDISFKVIADHIRAVTFAIGD--GALPSNEGRGYIIRRLLRRA 315
Cdd:PRK01584 236 IAFLQGKSSVYDTEAFTPIIKRIEKISGK-IYGQNEEDDRSIRIIADHIRAACFILGDpfVVLPSNVGQGYVLRRLIRRS 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 316 VLHGRKLGISQVFLKDLVPVVGEIMISYYPEIAKNADYIASIVEAEEIRFNKTLTDGLSLLDDVIEQAKSKKgIIDGAIA 395
Cdd:PRK01584 315 IRHAKKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFIKLIPNLGSSK-IIPGDIA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 396 FKLYDTYGFPYELTEEYATDEGLKVDRDGFDEQMKAQQERARSarsnkasmgvqnelltglktpsqyvgwseltveqtel 475
Cdd:PRK01584 394 FKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSKK------------------------------------- 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 476 vnlivdnklveeanagqvqaifaktpfyaemGGQVADLGMIYDESGQavakvtdvqnapngqhlhtlsiiaplfvgkqyk 555
Cdd:PRK01584 437 -------------------------------GADKVFKGGLADHSYE--------------------------------- 452
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 556 ldvdrpyhvaVSKNHTATHLLDQTLRNVLGEHTTQAGSLVTAEGLRYDFTYNGAVPSEKLQEVEDIINQKIIDNLPISWI 635
Cdd:PRK01584 453 ----------TTKLHTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVKKE 522
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1751980632 636 ETDIESAKKLGAVAVFTEKYGEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRIEAVTGS 707
Cdd:PRK01584 523 VMSLEEAREKGAMALFGEKYEDIVKVYEIDGFSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAILID 594
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-243 |
7.46e-111 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 339.34 E-value: 7.46e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 6 SAEVRSLFLRFFESKGHKIEPSQSLIPQNDPTLLWINSGVATLKKYFDGSVVPENHRITNAQKSIRTNDIENVGHTARHH 85
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPANRLVNSQKCIRAGDIDNVGKTGRHH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 86 TLFEMMGNFSIGDYFKEEAIPWAWELLTspEWFGMDPDKLYVTVYPNDDQAKDIWLHKVGLPKDHLYE--EPDNFWDIG- 162
Cdd:cd00673 81 TFFEMLGNFSFGDYFKEEAIAFAWELLT--EVLGLPKDRLYVSVFEGDDEEEAIWWWKIGLPGIRIERigFKDNFWEMGg 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 163 EGPSGPDSEIFYDRGEEFNdpdeAENYPGGENERYLEIWNLVFSQFNHlpglTDNKDYPELPTKNIDTGMGLERVVSVFQ 242
Cdd:cd00673 159 NGPCGPCSEIFYDRGEERD----AASLPNEDDDRYLEIWNLVFMQYNR----DADGTYRPLPKKIVDTGMGLERLVWVLQ 230
|
.
gi 1751980632 243 H 243
Cdd:cd00673 231 G 231
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
496-702 |
1.10e-25 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 106.43 E-value: 1.10e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 496 IFAKTPFYAEMGGQVADLGMIYDESGQAvaKVTDVQnAPNGQHLHTLSIIAPLFVGKQYKLDVDRPYHVAVSKNHTATHL 575
Cdd:COG2872 29 VLDRTAFYPTGGGQPGDTGTLVWDGKEI--RVVDVR-KEDGEIVHVLEGAPLPEVGDEVTGEIDWERRYRHMRLHTALHL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 576 LDQTLRNVLGEHTTqaGSLVTAEGLRYDFTYNGAvPSEKLQEVEDIINQKIIDNLPISWIETDIESAKKLGAV----AVF 651
Cdd:COG2872 106 LSAVVYREYGAPVT--GGQIGEDRARIDFDLPEF-DEEDLEEIEAEANELIAADLPVRIYWITREELEAIPGLvrtmSVL 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1751980632 652 TEKYGEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRIE 702
Cdd:COG2872 183 PPPGVGRVRIVEIGGVDLQPCGGTHVANTGEIGRIKITKIEKKGKGNRRVY 233
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
659-701 |
1.19e-14 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 68.56 E-value: 1.19e-14
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1751980632 659 VRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRI 701
Cdd:smart00863 1 VRVVSIGDFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
659-701 |
5.42e-13 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 63.62 E-value: 5.42e-13
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 1751980632 659 VRVVSIGDYNAEFDGGTHANSTAELGMFKIVGEQGTGAGVRRI 701
Cdd:pfam07973 1 VRVVSIGDFDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
742-879 |
4.78e-12 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 64.39 E-value: 4.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 742 LQTALKEAERQAASLEQKLANQEADAAFANPQKINNYTLIATEMAVE-SMDVLRSTADTWKQSTPSDVLVLAANL-GEKV 819
Cdd:pfam02272 4 LNEELKELEKELEELKEALALLKAKELLEKAEEINGVKVLVAEVGEGwDAGALGIAADRLKKKLGDPVIVLVAKEdGDKV 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 820 NLLVAVAPeavKKGIKAGDLVKSIAPAIGGGGGGRpDMAQAGGKNPAGIADAFKQAADWL 879
Cdd:pfam02272 84 KVSARSSK---DKGVDAGELLKEVAAILGGGGGGH-DLAAGAGIDAEKLDEALELLEEAI 139
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
491-690 |
4.87e-10 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 60.48 E-value: 4.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 491 GQVQAIFAKTPFYAEMGGQVADLGMIYDESGQAVAKVTDVQNApNGQHLH-------TLSIIAPLFVGKQYKLDVDRPYH 563
Cdd:PLN02961 1 GRIALVLDRTIFHPQGGGQPSDTGRIVISGGDTKFSVQDVRRK-DGVVYHygvfegsNPESASPFEAGDEVTVTVDESRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751980632 564 VAVSKNHTATHLLDQTLRNVlgehttQAGSLVTAEGlrYDF------TYNGAVPSE----KLQEVEDIINQKIIDNLPIS 633
Cdd:PLN02961 80 KLHSRLHSAGHLLDVCMARV------GLGPLEPGKG--YHFpdgpfvEYKGKIPQGeldsKQDELEAEANELIAEGGKVS 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1751980632 634 WIETDIESAKKL--GAVAVFTEKyGEKVRVVSIGDYNAEFDGGTHANSTAELGMFKIVG 690
Cdd:PLN02961 152 AAVLPYDEAAELcgGSLPDYIAK-DSTPRIVKIGDSPGCPCGGTHVADVSEITSVKVTQ 209
|
|
| |
