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Conserved domains on  [gi|1757329025|ref|WP_151045925|]
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BCCT family transporter [Comamonas kerstersii]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
9-512 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 657.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025   9 TTAARKPRMTFAPAVVLPSLLVLGALLVLCGFYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRL 88
Cdd:COG1292     3 DKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  89 GPDDAKPEFSFASWTAMLFAAGMGIGLMYFGVGEPLQHYLNPPTQ-EAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVL 167
Cdd:COG1292    83 GGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLAL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 168 AYFGFRYNLPLTMRSGLYPLLQKRINGPIGHSVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVV 247
Cdd:COG1292   163 AYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTV-QIIIIAV 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 248 VVGLAGLSAASGLDKGVKRLSEVNLLITFALLGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEvakDDGWFGG 327
Cdd:COG1292   242 ITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYG---DTGWLGG 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 328 WTILYWAWWISWSPFVGMFIARISRGRTVREFIVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFR 407
Cdd:COG1292   319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAGVEAALFA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 408 FFEYLPLAKAVSWIAVLLITLFFVTSADSGAYVVDAIASRGHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVT 487
Cdd:COG1292   399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIIT 478
                         490       500
                  ....*....|....*....|....*
gi 1757329025 488 ALPVAAIMVLLCIGLWRGMKADLAH 512
Cdd:COG1292   479 ALPFSFVLLLMCVSLVKALREDPRR 503
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
9-512 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 657.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025   9 TTAARKPRMTFAPAVVLPSLLVLGALLVLCGFYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRL 88
Cdd:COG1292     3 DKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  89 GPDDAKPEFSFASWTAMLFAAGMGIGLMYFGVGEPLQHYLNPPTQ-EAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVL 167
Cdd:COG1292    83 GGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLAL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 168 AYFGFRYNLPLTMRSGLYPLLQKRINGPIGHSVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVV 247
Cdd:COG1292   163 AYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTV-QIIIIAV 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 248 VVGLAGLSAASGLDKGVKRLSEVNLLITFALLGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEvakDDGWFGG 327
Cdd:COG1292   242 ITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYG---DTGWLGG 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 328 WTILYWAWWISWSPFVGMFIARISRGRTVREFIVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFR 407
Cdd:COG1292   319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAGVEAALFA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 408 FFEYLPLAKAVSWIAVLLITLFFVTSADSGAYVVDAIASRGHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVT 487
Cdd:COG1292   399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIIT 478
                         490       500
                  ....*....|....*....|....*
gi 1757329025 488 ALPVAAIMVLLCIGLWRGMKADLAH 512
Cdd:COG1292   479 ALPFSFVLLLMCVSLVKALREDPRR 503
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
40-509 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 596.06  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  40 FYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRLGPDDAKPEFSFASWTAMLFAAGMGIGLMYFG 119
Cdd:pfam02028  18 IFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSWFAMLFAAGMGIGLVFWG 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 120 VGEPLQHYLN-PPTQEAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSGLYPLLQKRINGPIGH 198
Cdd:pfam02028  98 VAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLISSALYPLLGDRIDGPIGK 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 199 SVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFAL 278
Cdd:pfam02028 178 AIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTT-QLAIIAIITALFTISAVSGLDKGIKRLSNLNMYLAVAL 256
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 279 LGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEvaKDDGWFGGWTILYWAWWISWSPFVGMFIARISRGRTVRE 358
Cdd:pfam02028 257 LLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFG--DTGGWLGGWTIFYWAWWIAWAPFVGMFIARISRGRTIRE 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 359 FIVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADSGA 438
Cdd:pfam02028 335 FILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADAVEAGPPAALFALLEQLPLGTILSVLALLLIIIFFVTSADSGT 414
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1757329025 439 YVVDAIASRGHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKAD 509
Cdd:pfam02028 415 LVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISLFKALREE 485
PRK09928 PRK09928
choline transport protein BetT; Provisional
40-684 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 558.93  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  40 FYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRLGPDDAKPEFSFASWTAMLFAAGMGIGLMYFG 119
Cdd:PRK09928   36 LFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFS 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 120 VGEPLQHYLNPPTQEAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSGLYPLLQKRINGPIGHS 199
Cdd:PRK09928  116 VAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHS 195
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 200 VDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFALL 279
Cdd:PRK09928  196 VDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAA-QAALIALSVIIATISVTSGVNKGIRVLSELNVLLALGLI 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 280 GFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEVAKDdgWFGGWTILYWAWWISWSPFVGMFIARISRGRTVREF 359
Cdd:PRK09928  275 LFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTE--WMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQF 352
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 360 IVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADSGAY 439
Cdd:PRK09928  353 VLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGAL 432
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 440 VVDAIASR---GHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKAD---LAHA 513
Cdd:PRK09928  433 VLGNFTSKlkdINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEdyrRASA 512
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 514 GQDLAPATSFWTGQ-HWRKRLEQIVRQPTEADVNRFLKVSVLPAMQEVVAEMRKQGVDARVQdDTAVTEGADAGSVRLIV 592
Cdd:PRK09928  513 NRDTAPRLVGLQDRlNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQELRLRGAYVELN-ELPPEEDERLGHLDLLV 591
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 593 PITGLRDFVYGVRPVTRRLPGFMLTEVTDDEANVRRHvvepiTFFEDGREGYDVQYLRQEELIADILRNYERYLSLMADQ 672
Cdd:PRK09928  592 HLGDEQNFVYQIWPQRYSVPGFTYRARSGKSTYYRLE-----TFLLEGSQGNDLMDYSKEQVINDILDQYERHLNFLHLH 666
                         650
                  ....*....|..
gi 1757329025 673 RtvllnRAPGHT 684
Cdd:PRK09928  667 R-----EAPGNS 673
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
62-509 3.70e-167

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 486.86  E-value: 3.70e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  62 WFYTVAVTGFLVFLVLIAWSRYGDIRLGPDDAKPEFSFASWTAMLFAAGMGIGLMYFGVGEPLQHYLNPPTQEAGTP-AA 140
Cdd:TIGR00842   2 WAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTStTA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 141 AREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSGLYPLLQKRINGPIGHSVDAFALVGTIAGLATTLGYGA 220
Cdd:TIGR00842  82 QEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 221 LQLAAGLNLVtGWDTGTTAFRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFALLGFVLLCGPTVFLLQAFSENIG 300
Cdd:TIGR00842 162 PQINAGLSAL-FGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 301 NYLSSLVGMSLRTFTYEvaKDDGWFGGWTILYWAWWISWSPFVGMFIARISRGRTVREFIVGVLFIPTAFNLLWMTVFGN 380
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDD--GKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGN 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 381 GAIWIDTHVAQGAL-SATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADSGAYVVDAIASRG---HPQSPVWQ 456
Cdd:TIGR00842 319 SALLLQQNGGFINGpFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWV 398
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1757329025 457 RLFWAAVLG-MTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKAD 509
Cdd:TIGR00842 399 RVFWAVAIGlIALVLLFSGGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
9-512 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 657.22  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025   9 TTAARKPRMTFAPAVVLPSLLVLGALLVLCGFYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRL 88
Cdd:COG1292     3 DKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  89 GPDDAKPEFSFASWTAMLFAAGMGIGLMYFGVGEPLQHYLNPPTQ-EAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVL 167
Cdd:COG1292    83 GGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLAL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 168 AYFGFRYNLPLTMRSGLYPLLQKRINGPIGHSVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVV 247
Cdd:COG1292   163 AYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTV-QIIIIAV 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 248 VVGLAGLSAASGLDKGVKRLSEVNLLITFALLGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEvakDDGWFGG 327
Cdd:COG1292   242 ITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYG---DTGWLGG 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 328 WTILYWAWWISWSPFVGMFIARISRGRTVREFIVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFR 407
Cdd:COG1292   319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAGVEAALFA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 408 FFEYLPLAKAVSWIAVLLITLFFVTSADSGAYVVDAIASRGHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVT 487
Cdd:COG1292   399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIIT 478
                         490       500
                  ....*....|....*....|....*
gi 1757329025 488 ALPVAAIMVLLCIGLWRGMKADLAH 512
Cdd:COG1292   479 ALPFSFVLLLMCVSLVKALREDPRR 503
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
40-509 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 596.06  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  40 FYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRLGPDDAKPEFSFASWTAMLFAAGMGIGLMYFG 119
Cdd:pfam02028  18 IFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSWFAMLFAAGMGIGLVFWG 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 120 VGEPLQHYLN-PPTQEAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSGLYPLLQKRINGPIGH 198
Cdd:pfam02028  98 VAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLISSALYPLLGDRIDGPIGK 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 199 SVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFAL 278
Cdd:pfam02028 178 AIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTT-QLAIIAIITALFTISAVSGLDKGIKRLSNLNMYLAVAL 256
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 279 LGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEvaKDDGWFGGWTILYWAWWISWSPFVGMFIARISRGRTVRE 358
Cdd:pfam02028 257 LLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFG--DTGGWLGGWTIFYWAWWIAWAPFVGMFIARISRGRTIRE 334
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 359 FIVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADSGA 438
Cdd:pfam02028 335 FILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADAVEAGPPAALFALLEQLPLGTILSVLALLLIIIFFVTSADSGT 414
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1757329025 439 YVVDAIASRGHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKAD 509
Cdd:pfam02028 415 LVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISLFKALREE 485
PRK09928 PRK09928
choline transport protein BetT; Provisional
40-684 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 558.93  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  40 FYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRLGPDDAKPEFSFASWTAMLFAAGMGIGLMYFG 119
Cdd:PRK09928   36 LFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFS 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 120 VGEPLQHYLNPPTQEAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSGLYPLLQKRINGPIGHS 199
Cdd:PRK09928  116 VAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHS 195
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 200 VDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTGTTAfRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFALL 279
Cdd:PRK09928  196 VDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAA-QAALIALSVIIATISVTSGVNKGIRVLSELNVLLALGLI 274
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 280 GFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYEVAKDdgWFGGWTILYWAWWISWSPFVGMFIARISRGRTVREF 359
Cdd:PRK09928  275 LFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTE--WMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQF 352
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 360 IVGVLFIPTAFNLLWMTVFGNGAIWIDTHVAQGALSATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADSGAY 439
Cdd:PRK09928  353 VLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGAL 432
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 440 VVDAIASR---GHPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKAD---LAHA 513
Cdd:PRK09928  433 VLGNFTSKlkdINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEdyrRASA 512
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 514 GQDLAPATSFWTGQ-HWRKRLEQIVRQPTEADVNRFLKVSVLPAMQEVVAEMRKQGVDARVQdDTAVTEGADAGSVRLIV 592
Cdd:PRK09928  513 NRDTAPRLVGLQDRlNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQELRLRGAYVELN-ELPPEEDERLGHLDLLV 591
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 593 PITGLRDFVYGVRPVTRRLPGFMLTEVTDDEANVRRHvvepiTFFEDGREGYDVQYLRQEELIADILRNYERYLSLMADQ 672
Cdd:PRK09928  592 HLGDEQNFVYQIWPQRYSVPGFTYRARSGKSTYYRLE-----TFLLEGSQGNDLMDYSKEQVINDILDQYERHLNFLHLH 666
                         650
                  ....*....|..
gi 1757329025 673 RtvllnRAPGHT 684
Cdd:PRK09928  667 R-----EAPGNS 673
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
62-509 3.70e-167

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 486.86  E-value: 3.70e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  62 WFYTVAVTGFLVFLVLIAWSRYGDIRLGPDDAKPEFSFASWTAMLFAAGMGIGLMYFGVGEPLQHYLNPPTQEAGTP-AA 140
Cdd:TIGR00842   2 WAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTStTA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 141 AREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSGLYPLLQKRINGPIGHSVDAFALVGTIAGLATTLGYGA 220
Cdd:TIGR00842  82 QEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLGA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 221 LQLAAGLNLVtGWDTGTTAFRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFALLGFVLLCGPTVFLLQAFSENIG 300
Cdd:TIGR00842 162 PQINAGLSAL-FGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 301 NYLSSLVGMSLRTFTYEvaKDDGWFGGWTILYWAWWISWSPFVGMFIARISRGRTVREFIVGVLFIPTAFNLLWMTVFGN 380
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDD--GKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGN 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 381 GAIWIDTHVAQGAL-SATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADSGAYVVDAIASRG---HPQSPVWQ 456
Cdd:TIGR00842 319 SALLLQQNGGFINGpFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWV 398
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1757329025 457 RLFWAAVLG-MTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKAD 509
Cdd:TIGR00842 399 RVFWAVAIGlIALVLLFSGGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09950 PRK09950
putative transporter; Provisional
40-512 1.56e-62

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 216.58  E-value: 1.56e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  40 FYPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRLGpdDAKPEFSFASWTAMLFAAGMGIGLMYFG 119
Cdd:PRK09950   29 LFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLG--EGKPEYSTLSWLFMFICAGLGSSTLYWG 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 120 VGEPLQHYLNPPTQEAG-TPAAAREALTSTFFHWGFQAWAIYGVMGLVLAY-FGFRYNLPLTMRSGLYPLLQKRINGPIG 197
Cdd:PRK09950  107 VMEWAYYYQTPGLNIAPrSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFHVRKNKGLSLSGIIAAITGVKPQGPWG 186
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 198 HSVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTgTTAFRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFA 277
Cdd:PRK09950  187 RLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPN-NFTVQAFVILLSGVIFCLSSYIGIDNGLQRLSKMVGWGAFL 265
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 278 LLGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTftyeVAKDDGWFG-GWTILYWAWWISWSPFVGMFIARISRGRTV 356
Cdd:PRK09950  266 FALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFT----DPMGDGSFTrNWTVFYWLWWISYTPGVAMFVTRVSRGRKI 341
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 357 REFIVGVLFIPTAFNLLWMTVFGNGAI--WIDTHVAQGALSATASNvDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSA 434
Cdd:PRK09950  342 KEVIWGLILGSSVGCWFFFGVLESYAIhqFINGVINVPQILNTLGG-ETAVQQLLSSLPAGKLFLAAYLGIMIIFLASHM 420
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 435 DSGAYVVDAIASRG--HPQSPVWQ-RLFWAAVLGMTAV-VLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMKADL 510
Cdd:PRK09950  421 DAVAYTMAATSTRNlrEGDDPDRGlRLFWCVVITLIPLsILFTGASLDTMKTTVVLTALPFLVILLIKVYGFIRWLKQDY 500

                  ..
gi 1757329025 511 AH 512
Cdd:PRK09950  501 AD 502
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
41-507 2.03e-59

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 208.05  E-value: 2.03e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025  41 YPQRADQLFGSAQAWVVTNFDWFYTVAVTGFLVFLVLIAWSRYGDIRLGpdDAKPEFSFASWTAMLFAAGMGIGLMYFGV 120
Cdd:PRK03356   32 DLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLG--DEKPEFSTASWIFMMFASCTSAAVLFWGS 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 121 GEPLQHYLNPPTQ-EAGTPAAAREALTSTFFHWGFQAWAIYGVMGLVLAYFGFRYNLPLTMRSG-LYPLL-QKRINGPIG 197
Cdd:PRK03356  110 IEIYYYISTPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFVRKMDVIRPSStLVPLVgEKHAKGLFG 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 198 HSVDAFALVGTIAGLATTLGYGALQLAAGLNLVTGWDTgTTAFRIAVIVVVVGLAGLSAASGLDKGVKRLSEVNLLITFA 277
Cdd:PRK03356  190 TIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPH-TLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFL 268
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 278 LLGFVLLCGPTVFLLQAFSENIGNYLSSLVGMSLRTFTYevaKDDGWFGGWTILYWAWWISWSPFVGMFIARISRGRTVR 357
Cdd:PRK03356  269 MLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPI---GKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVR 345
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1757329025 358 EFIVGVLFIPTAFNLLWMTVFGNGAIW-IDTHVAQGALSATASNVDALLFRFFEYLPLAKAVSWIAVLLITLFFVTSADS 436
Cdd:PRK03356  346 ELCFGMVLGLTASTWILWTVLGSNTLLlMDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLINA 425
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1757329025 437 GAYVVDAIASRG---HPQSPVWQRLFWAAVLGMTAVVLLLAGGLKALQAMTLVTALPVAAIMVLLCIGLWRGMK 507
Cdd:PRK03356  426 CSYTLAMSTCREvrdGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAK 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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