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Conserved domains on  [gi|1780291898|ref|WP_155647884|]
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helix-turn-helix domain-containing protein, partial [Vibrio sp. CUB2]

Protein Classification

transposase( domain architecture ID 706766)

IS30 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  24499397|30454069

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Tra8 super family cl28582
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
1-73 1.09e-18

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG2826:

Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 77.23  E-value: 1.09e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1780291898   1 MRYTHLTENERYMISALRKQGISTAKIAKQLGRHKATIYREIERNSRynrhfkRYSYQAWRAQQMARNRLSRS 73
Cdd:COG2826     2 RSYKHLTLEEREEIEALLKAGLSVREIARRLGRSPSTISRELKRNSG------RRGYRAEGAQRLAEDRRRRP 68
 
Name Accession Description Interval E-value
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
1-73 1.09e-18

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 77.23  E-value: 1.09e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1780291898   1 MRYTHLTENERYMISALRKQGISTAKIAKQLGRHKATIYREIERNSRynrhfkRYSYQAWRAQQMARNRLSRS 73
Cdd:COG2826     2 RSYKHLTLEEREEIEALLKAGLSVREIARRLGRSPSTISRELKRNSG------RRGYRAEGAQRLAEDRRRRP 68
HTH_38 pfam13936
Helix-turn-helix domain; This helix-turn-helix domain is often found in transferases and is ...
 2-45 9.75e-09

Helix-turn-helix domain; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433591 [Multi-domain]  Cd Length: 44  Bit Score: 45.97  E-value: 9.75e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 1780291898  2 RYTHLTENERYMISALRKQGISTAKIAKQLGRHKATIYREIERN 45
Cdd:pfam13936  1 KGKHLSLEEREEIARLLAEGLSLREIARRLGRSPSTISRELRRN 44
transpos_IS630 NF033545
IS630 family transposase;
10-44 1.60e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 34.92  E-value: 1.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1780291898  10 ERYMISALRKQGISTAKIAKQLGRHKATIYREIER 44
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKR 35
 
Name Accession Description Interval E-value
Tra8 COG2826
Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];
1-73 1.09e-18

Transposase and inactivated derivatives, IS30 family [Mobilome: prophages, transposons];


Pssm-ID: 442074 [Multi-domain]  Cd Length: 325  Bit Score: 77.23  E-value: 1.09e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1780291898   1 MRYTHLTENERYMISALRKQGISTAKIAKQLGRHKATIYREIERNSRynrhfkRYSYQAWRAQQMARNRLSRS 73
Cdd:COG2826     2 RSYKHLTLEEREEIEALLKAGLSVREIARRLGRSPSTISRELKRNSG------RRGYRAEGAQRLAEDRRRRP 68
HTH_38 pfam13936
Helix-turn-helix domain; This helix-turn-helix domain is often found in transferases and is ...
 2-45 9.75e-09

Helix-turn-helix domain; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433591 [Multi-domain]  Cd Length: 44  Bit Score: 45.97  E-value: 9.75e-09
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 1780291898  2 RYTHLTENERYMISALRKQGISTAKIAKQLGRHKATIYREIERN 45
Cdd:pfam13936  1 KGKHLSLEEREEIARLLAEGLSLREIARRLGRSPSTISRELRRN 44
transpos_IS630 NF033545
IS630 family transposase;
10-44 1.60e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 34.92  E-value: 1.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1780291898  10 ERYMISALRKQGISTAKIAKQLGRHKATIYREIER 44
Cdd:NF033545    1 RRARILLLAAEGLSITEIAERLGVSRSTVYRWLKR 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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