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Conserved domains on  [gi|1783482540|ref|WP_156411964|]
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efflux RND transporter permease subunit, partial [Legionella bozemanae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ACR_tran super family cl47191
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 2-76 2.18e-33

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


The actual alignment was detected with superfamily member TIGR00914:

Pssm-ID: 481531 [Multi-domain]  Cd Length: 1051  Bit Score: 119.87  E-value: 2.18e-33
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1783482540    2 LARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPPSKDSERHFIPLSEVA 76
Cdd:TIGR00914  736 AARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDARKQFIPLSDVA 810
 
Name Accession Description Interval E-value
2A0601 TIGR00914
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ...
 2-76 2.18e-33

heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 129992 [Multi-domain]  Cd Length: 1051  Bit Score: 119.87  E-value: 2.18e-33
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1783482540    2 LARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPPSKDSERHFIPLSEVA 76
Cdd:TIGR00914  736 AARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDARKQFIPLSDVA 810
CusA COG3696
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
2-77 1.51e-25

Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];


Pssm-ID: 442911 [Multi-domain]  Cd Length: 1031  Bit Score: 97.41  E-value: 1.51e-25
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1783482540    2 LARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPpskdsERHFIPLSEVAK 77
Cdd:COG3696    727 AARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTP-----SGAQVPLSQVAD 797
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 1-77 7.41e-17

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 72.71  E-value: 7.41e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1783482540    1 TLARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPPSKdserhFIPLSEVAK 77
Cdd:pfam00873  724 KAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGK-----MIPLSAFAK 795
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
1-77 2.80e-05

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 40.00  E-value: 2.80e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1783482540    1 TLARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVplpPSKDSERhfIPLSEVAK 77
Cdd:NF033617   712 KAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYV---RSNDGKL--VPLSTLAK 783
 
Name Accession Description Interval E-value
2A0601 TIGR00914
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ...
 2-76 2.18e-33

heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 129992 [Multi-domain]  Cd Length: 1051  Bit Score: 119.87  E-value: 2.18e-33
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1783482540    2 LARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPPSKDSERHFIPLSEVA 76
Cdd:TIGR00914  736 AARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDARKQFIPLSDVA 810
CusA COG3696
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
2-77 1.51e-25

Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];


Pssm-ID: 442911 [Multi-domain]  Cd Length: 1031  Bit Score: 97.41  E-value: 1.51e-25
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1783482540    2 LARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPpskdsERHFIPLSEVAK 77
Cdd:COG3696    727 AARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTP-----SGAQVPLSQVAD 797
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
 1-77 7.41e-17

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 72.71  E-value: 7.41e-17
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1783482540    1 TLARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPPSKdserhFIPLSEVAK 77
Cdd:pfam00873  724 KAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGK-----MIPLSAFAK 795
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
3-77 7.63e-12

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 58.58  E-value: 7.63e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1783482540    3 ARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVPLPpskdsERHFIPLSEVAK 77
Cdd:COG0841    715 AALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTP-----DGEMVPLSSVAT 784
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
1-77 2.80e-05

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 40.00  E-value: 2.80e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1783482540    1 TLARYGLQVGAVQDAIVIATGGKKGGELFEGDKRFDIVVRLPESFRADPDVLREVFVplpPSKDSERhfIPLSEVAK 77
Cdd:NF033617   712 KAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYV---RSNDGKL--VPLSTLAK 783
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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