|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
1-362 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 692.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 1 MNQtIFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQ 80
Cdd:PRK05355 1 MMR-VYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 81 FAMVPLNLMRGHGKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFD 160
Cdd:PRK05355 80 FAMVPMNLLGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASSEDDGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 161 FIPDLGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTP 240
Cdd:PRK05355 160 ELPDTGDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 241 PTFAIYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESrGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSH 320
Cdd:PRK05355 240 PTFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSS-DFYRNPVAPEDRSRMNVPFTLADEELDKKFLAEAKAA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1815881133 321 GLIQLKGHRSVGGMRASIYNAMPEAGVQILADYLRDFARQHG 362
Cdd:PRK05355 319 GLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERRHG 360
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
5-361 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 653.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 5 IFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMV 84
Cdd:COG1932 3 VYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 85 PLNLMRGHGKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPD 164
Cdd:COG1932 83 PMNLLRGGKKADYLVTGEWSKKAIKEAKKYGEVNVVASSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHELPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 165 LGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFA 244
Cdd:COG1932 163 VGDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPPTFA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 245 IYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESrGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQ 324
Cdd:COG1932 243 IYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDAS-DFYTNPVDPEDRSRMNVTFDLADEELDAAFLAEAKAAGLVG 321
|
330 340 350
....*....|....*....|....*....|....*..
gi 1815881133 325 LKGHRSVGGMRASIYNAMPEAGVQILADYLRDFARQH 361
Cdd:COG1932 322 LKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
6-359 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 584.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 6 FNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMVP 85
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 86 LNLMRGHGKASYVQTGIWSKKAIAEARRF-TAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPD 164
Cdd:cd00611 81 LNLLGDKGTADYVVTGAWSAKAAKEAKRYgGVVVIVAAKEEGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEVPD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 165 LGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFA 244
Cdd:cd00611 161 TGGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTFA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 245 IYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESRGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQ 324
Cdd:cd00611 241 IYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRLGKEELEKEFLKEAEAAGMIG 320
|
330 340 350
....*....|....*....|....*....|....*
gi 1815881133 325 LKGHRSVGGMRASIYNAMPEAGVQILADYLRDFAR 359
Cdd:cd00611 321 LKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
13-361 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 562.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 13 AVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMVPLNLMRGH 92
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNLLAEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 93 GKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPDLGDIPLVS 172
Cdd:TIGR01364 81 KVADYIVTGAWSKKAAKEAKKYGVVNVVASGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPLVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 173 DASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFAIYVAGLVF 252
Cdd:TIGR01364 161 DMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGLVF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 253 KWLKQLGGLERMAEINARKARLLYDAIDESRGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQLKGHRSVG 332
Cdd:TIGR01364 241 KWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGNEELEKRFLKEAEERGLVSLKGHRSVG 320
|
330 340
....*....|....*....|....*....
gi 1815881133 333 GMRASIYNAMPEAGVQILADYLRDFARQH 361
Cdd:TIGR01364 321 GMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
5-350 |
9.24e-63 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 204.79 E-value: 9.24e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 5 IFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSvmEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGaTLQFAMV 84
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGT-TEAINLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 85 PLNLMRGHGK---ASYVQTGIWS-KKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFD 160
Cdd:pfam00266 78 ALSLGRSLKPgdeIVITEMEHHAnLVPWQELAKRTGARVRVLPLDEDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 161 fIPDLGDIP------LVSDASSHILSKPTDVSRFG--LIYAGAQKNIGPAGLTLVIVRDDLLGHAPA-------NTATML 225
Cdd:pfam00266 158 -VPEIGKLAhqygalVLVDAAQAIGHRPIDVQKLGvdFLAFSGHKLYGPTGIGVLYGRRDLLEKMPPllggggmIETVSL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 226 DYAVYAKEESM--HNTPPTFAIYVAGLVFKWLkQLGGLERMAEINARKARLLYDAIDESRGFYANPVEtRNRSRMNVPFT 303
Cdd:pfam00266 237 QESTFADAPWKfeAGTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPE-RRASIISFNFK 314
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1815881133 304 LADAAMDEAFLkgaRSHGLIQLKGHRSV----------GGMRASIYNAMPEAGVQIL 350
Cdd:pfam00266 315 GVHPHDVATLL---DESGIAVRSGHHCAqplmvrlglgGTVRASFYIYNTQEDVDRL 368
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05355 |
PRK05355 |
3-phosphoserine/phosphohydroxythreonine transaminase; |
1-362 |
0e+00 |
|
3-phosphoserine/phosphohydroxythreonine transaminase;
Pssm-ID: 235428 Cd Length: 360 Bit Score: 692.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 1 MNQtIFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQ 80
Cdd:PRK05355 1 MMR-VYNFSAGPAMLPEEVLEQAQQELLDWNGSGMSVMEISHRSKEFEAVAEEAEADLRELLNIPDNYKVLFLQGGASLQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 81 FAMVPLNLMRGHGKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFD 160
Cdd:PRK05355 80 FAMVPMNLLGGGKKADYVDTGSWSKKAIKEAKKYGEVNVAASSEDDGFTYIPPLDEWQLSDDAAYVHYTSNETIDGTEFH 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 161 FIPDLGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTP 240
Cdd:PRK05355 160 ELPDTGDVPLVADMSSDILSRPIDVSKFGLIYAGAQKNIGPAGLTIVIVREDLLGRALPSIPSMLDYKTHADNDSMYNTP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 241 PTFAIYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESrGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSH 320
Cdd:PRK05355 240 PTFAIYLAGLVFKWLKEQGGVAAMEKRNQEKAALLYDAIDSS-DFYRNPVAPEDRSRMNVPFTLADEELDKKFLAEAKAA 318
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1815881133 321 GLIQLKGHRSVGGMRASIYNAMPEAGVQILADYLRDFARQHG 362
Cdd:PRK05355 319 GLVGLKGHRSVGGMRASIYNAMPLEGVQALVDFMKEFERRHG 360
|
|
| SerC |
COG1932 |
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and ... |
5-361 |
0e+00 |
|
Phosphoserine aminotransferase [Coenzyme transport and metabolism, Amino acid transport and metabolism]; Phosphoserine aminotransferase is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 441535 Cd Length: 358 Bit Score: 653.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 5 IFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMV 84
Cdd:COG1932 3 VYNFSAGPAKLPEEVLEQAQAELLDWNGSGMSVMEMSHRSKPFKAIVEEAEADLRELLGIPDGYEVLFLQGGATAQFAMV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 85 PLNLMRGHGKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPD 164
Cdd:COG1932 83 PMNLLRGGKKADYLVTGEWSKKAIKEAKKYGEVNVVASSEDDNFGYIPKPEEWQLSPDADYVHYTSNETITGVEFHELPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 165 LGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFA 244
Cdd:COG1932 163 VGDVPLVADMSSDILSRPVDVSKFGLIYAGAQKNIGPAGLTVVIVRPDLLGRAERAIPSMLDYKTHADNDSMYNTPPTFA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 245 IYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESrGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQ 324
Cdd:COG1932 243 IYLAGLVLKWLKEQGGLAAMEKRNAEKAALLYDWIDAS-DFYTNPVDPEDRSRMNVTFDLADEELDAAFLAEAKAAGLVG 321
|
330 340 350
....*....|....*....|....*....|....*..
gi 1815881133 325 LKGHRSVGGMRASIYNAMPEAGVQILADYLRDFARQH 361
Cdd:COG1932 322 LKGHRSVGGMRASIYNAMPLEGVEALVDFMDEFERRH 358
|
|
| PSAT_like |
cd00611 |
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP) ... |
6-359 |
0e+00 |
|
Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as a dimer and catalyzes the conversion of phosphohydroxypyruvate to phosphoserine.
Pssm-ID: 99736 [Multi-domain] Cd Length: 355 Bit Score: 584.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 6 FNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMVP 85
Cdd:cd00611 1 INFSAGPAALPEEVLEQAQKELLDFNGLGMSVMEMSHRSKDFEAIVNEAESDLRELLNIPDNYKVLFLQGGATGQFAAVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 86 LNLMRGHGKASYVQTGIWSKKAIAEARRF-TAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPD 164
Cdd:cd00611 81 LNLLGDKGTADYVVTGAWSAKAAKEAKRYgGVVVIVAAKEEGKYTKIPDVETWDLAPDAAYVHYCSNETIHGVEFDEVPD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 165 LGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFA 244
Cdd:cd00611 161 TGGVPLVADMSSNILSRPIDVSKFGVIYAGAQKNLGPAGVTVVIVRKDLLGKARKITPSMLNYKTHADNNSLYNTPPTFA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 245 IYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESRGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQ 324
Cdd:cd00611 241 IYMMGLVLKWLKEQGGVEAMEKRNRQKAQLLYDTIDNSNGFYRGPVDKRARSRMNVPFRLGKEELEKEFLKEAEAAGMIG 320
|
330 340 350
....*....|....*....|....*....|....*
gi 1815881133 325 LKGHRSVGGMRASIYNAMPEAGVQILADYLRDFAR 359
Cdd:cd00611 321 LKGHRSVGGIRASIYNALSLEGVQALADFMKEFQK 355
|
|
| serC_1 |
TIGR01364 |
phosphoserine aminotransferase; This model represents the common form of the phosphoserine ... |
13-361 |
0e+00 |
|
phosphoserine aminotransferase; This model represents the common form of the phosphoserine aminotransferase SerC. The phosphoserine aminotransferase of the archaeon Methanosarcina barkeri and putative phosphoserine aminotransferase of Mycobacterium tuberculosis are represented by separate models. All are members of the class V aminotransferases (pfam00266). [Amino acid biosynthesis, Serine family]
Pssm-ID: 130431 Cd Length: 349 Bit Score: 562.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 13 AVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMVPLNLMRGH 92
Cdd:TIGR01364 1 AALPEEVLEQAQKELLNFNGTGMSVMEISHRSKEFEAVANEAESDLRELLNIPDNYEVLFLQGGATGQFAAVPLNLLAEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 93 GKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPDLGDIPLVS 172
Cdd:TIGR01364 81 KVADYIVTGAWSKKAAKEAKKYGVVNVVASGKEGNYTKIPDPSTWEISEDAAYVHYCANETIHGVEFRELPDVKNAPLVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 173 DASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFAIYVAGLVF 252
Cdd:TIGR01364 161 DMSSNILSRPIDVSKFGLIYAGAQKNIGPAGLTVVIVRKDLLGRASRITPSMLNYKIHAENDSMYNTPPTFAIYVSGLVF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 253 KWLKQLGGLERMAEINARKARLLYDAIDESRGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQLKGHRSVG 332
Cdd:TIGR01364 241 KWLKEQGGVKAIEKRNQAKAQLLYDTIDNSNGFYRNPVDPRNRSRMNVVFTLGNEELEKRFLKEAEERGLVSLKGHRSVG 320
|
330 340
....*....|....*....|....*....
gi 1815881133 333 GMRASIYNAMPEAGVQILADYLRDFARQH 361
Cdd:TIGR01364 321 GMRASIYNAMPLEGVQALVDFMKEFQKKH 349
|
|
| PLN02452 |
PLN02452 |
phosphoserine transaminase |
5-361 |
0e+00 |
|
phosphoserine transaminase
Pssm-ID: 178071 Cd Length: 365 Bit Score: 538.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 5 IFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMV 84
Cdd:PLN02452 8 VFNFSAGPATLPANVLAKAQAELYNWEGSGMSVMEMSHRGKEFLSIIQKAEADLRELLDIPDNYEVLFLQGGASTQFAAI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 85 PLNLMRGHGKASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPD 164
Cdd:PLN02452 88 PLNLCKPGDKADFVVTGSWSKKAAKEAKKYCKTNVIASGKDEKYTKIPSVSEWELTPDAKFVHICANETIHGVEFKDYPD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 165 LGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFA 244
Cdd:PLN02452 168 VGNVPLVADMSSNFLSKPVDVSKYGVIYAGAQKNVGPSGVTIVIIRKDLIGNARPITPGMLDYKIHAENDSLYNTPPCFG 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 245 IYVAGLVFKWLKQLGGLERMAEINARKARLLYDAIDESRGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQ 324
Cdd:PLN02452 248 IYMCGLVFEDLLAQGGLKAMEKRNIRKADLLYDAIDESNGFYVCPVEKSVRSLMNVPFTLGGSELEAEFVKEAAKAGMVQ 327
|
330 340 350
....*....|....*....|....*....|....*..
gi 1815881133 325 LKGHRSVGGMRASIYNAMPEAGVQILADYLRDFARQH 361
Cdd:PLN02452 328 LKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQAKH 364
|
|
| PRK12462 |
PRK12462 |
phosphoserine aminotransferase; Provisional |
7-362 |
4.25e-141 |
|
phosphoserine aminotransferase; Provisional
Pssm-ID: 183540 Cd Length: 364 Bit Score: 404.58 E-value: 4.25e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 7 NFSAGPAVLPHVVLEQVQAELLDWHGSGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMVPL 86
Cdd:PRK12462 7 NFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAEADLRDLLGIPDEYGVVFLQGGSSLQFSMIPM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 87 NLMRGHGK-ASYVQTGIWSKKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFDFIPDL 165
Cdd:PRK12462 87 NFSRPGAAaPEYVTTGYWSRKAIGEASRVAAMRVVWDGAASGYRTLPSLAELDWDARAPFRHYVSNETVEGLQFPDAAGL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 166 GDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIGPAGLTLVIVRDDLLGHAPANTATMLDYAVYAKEESMHNTPPTFAI 245
Cdd:PRK12462 167 PDSPLIADMSSDFMSRPFDVEAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNTPPVFAI 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 246 YVAGLVFKWLK-QLGGLERMAEINARKARLLYDAIDESRGFYANPVETRNRSRMNVPFTLADAAMDEAFLKGARSHGLIQ 324
Cdd:PRK12462 247 YVMALVLRWIRdEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQSTEAGFCG 326
|
330 340 350
....*....|....*....|....*....|....*...
gi 1815881133 325 LKGHRSVGGMRASIYNAMPEAGVQILADYLRDFARQHG 362
Cdd:PRK12462 327 LSGHRSIGGIRASLYNAVSEQAVSRLCAFLKDFAIRHA 364
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
5-350 |
9.24e-63 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 204.79 E-value: 9.24e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 5 IFNFSAGPAVLPHVVLEQVQAELLDWHGSGMSvmEMSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGaTLQFAMV 84
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVHR--GVHTLGKEATQAYEEAREKVAEFINAPSNDEIIFTSGT-TEAINLV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 85 PLNLMRGHGK---ASYVQTGIWS-KKAIAEARRFTAVEIAASNEDRYASYVPMQADWQVSPDTAYVHITGNETIGGVEFD 160
Cdd:pfam00266 78 ALSLGRSLKPgdeIVITEMEHHAnLVPWQELAKRTGARVRVLPLDEDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 161 fIPDLGDIP------LVSDASSHILSKPTDVSRFG--LIYAGAQKNIGPAGLTLVIVRDDLLGHAPA-------NTATML 225
Cdd:pfam00266 158 -VPEIGKLAhqygalVLVDAAQAIGHRPIDVQKLGvdFLAFSGHKLYGPTGIGVLYGRRDLLEKMPPllggggmIETVSL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 226 DYAVYAKEESM--HNTPPTFAIYVAGLVFKWLkQLGGLERMAEINARKARLLYDAIDESRGFYANPVEtRNRSRMNVPFT 303
Cdd:pfam00266 237 QESTFADAPWKfeAGTPNIAGIIGLGAALEYL-SEIGLEAIEKHEHELAQYLYERLLSLPGIRLYGPE-RRASIISFNFK 314
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1815881133 304 LADAAMDEAFLkgaRSHGLIQLKGHRSV----------GGMRASIYNAMPEAGVQIL 350
Cdd:pfam00266 315 GVHPHDVATLL---DESGIAVRSGHHCAqplmvrlglgGTVRASFYIYNTQEDVDRL 368
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
8-327 |
5.45e-12 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 66.16 E-value: 5.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 8 FSAGPAVLPHVVLEqvqaelldwhgsGMSVMEMSHRGPEFMKIAAEAEQDLRDLLDiPANYKILFLQGGATLQFAMVPLN 87
Cdd:cd06451 3 LIPGPSNVPPRVLK------------AMNRPMLGHRSPEFLALMDEILEGLRYVFQ-TENGLTFLLSGSGTGAMEAALSN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 88 LMRGHGKASYVQTGIWSKKAIAEARRFTA-VEIaasnedryasyvpMQADW--QVSPDT----------AYVHITGNETI 154
Cdd:cd06451 70 LLEPGDKVLVGVNGVFGDRWADMAERYGAdVDV-------------VEKPWgeAVSPEEiaealeqhdiKAVTLTHNETS 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 155 GGVEFDfIPDLG------DIPLVSDASSHILSKPTDVSRFGL--IYAGAQKNIG-PAGLTLVIVRDDLLGHAPANTAT-- 223
Cdd:cd06451 137 TGVLNP-LEGIGalakkhDALLIVDAVSSLGGEPFRMDEWGVdvAYTGSQKALGaPPGLGPIAFSERALERIKKKTKPkg 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 224 ----MLDYAVYAKEESM-HNTPPTFAIY----VAGLVFKwlkqlGGLERMAEINARKARLLYDAIDEsRGF--YANPvet 292
Cdd:cd06451 216 fyfdLLLLLKYWGEGYSyPHTPPVNLLYalreALDLILE-----EGLENRWARHRRLAKALREGLEA-LGLklLAKP--- 286
|
330 340 350
....*....|....*....|....*....|....*
gi 1815881133 293 RNRSRMNVPFTLADAAMDEAFLKGARSHGLIQLKG 327
Cdd:cd06451 287 ELRSPTVTAVLVPEGVDGDEVVRRLMKRYNIEIAG 321
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
51-210 |
4.94e-11 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 60.86 E-value: 4.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 51 AAEAEQDLRDLLDiPANYKILFlQGGATLQFAMVPLNLMRGHGKASYVQTGIWSKKAIAEARR-FTAVEIAASNEDRYAS 129
Cdd:cd01494 2 LEELEEKLARLLQ-PGNDKAVF-VPSGTGANEAALLALLGPGDEVIVDANGHGSRYWVAAELAgAKPVPVPVDDAGYGGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 130 YVPMQADWQVSPDTAYVHITGNETIGGV-----EFDFIPDLGDIPLVSDASSHILSKPT-----DVSRFGLIYAGAQKNI 199
Cdd:cd01494 80 DVAILEELKAKPNVALIVITPNTTSGGVlvplkEIRKIAKEYGILLLVDAASAGGASPApgvliPEGGADVVTFSLHKNL 159
|
170
....*....|.
gi 1815881133 200 GPAGLTLVIVR 210
Cdd:cd01494 160 GGEGGGVVIVK 170
|
|
| PRK03080 |
PRK03080 |
phosphoserine transaminase; |
7-317 |
2.11e-08 |
|
phosphoserine transaminase;
Pssm-ID: 235103 Cd Length: 378 Bit Score: 55.19 E-value: 2.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 7 NFSAGP-AVLPHVVLEQVQAELLdwhGSgmsvmemSHRGPEFMKIAAEAEQDLRDLLDIPANYKILFLQGGATLQFAMVP 85
Cdd:PRK03080 15 RFSSGPcKKRPGWQLEALADALL---GR-------SHRQKPVKALLKRVIEGTRELLSLPEGYEVGIVPGSDTGAWEMAL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 86 LNLMRGHGkasyVQTGIW----SK--KAIAEARRFTAVEIAASNedrYASYV-PMQADWqvSPDTAYVHitgNETIGGVE 158
Cdd:PRK03080 85 WSLLGARR----VDHLAWesfgSKwaTDVVKQLKLEDPRVLEAD---YGSLPdLSAVDF--DRDVVFTW---NGTTTGVR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 159 ---FDFIPDLGDIPLVSDASSHILSKPTDVSRFGLIYAGAQKNIG-PAGLTLVIVR----DDLLGHAPA---------NT 221
Cdd:PRK03080 153 vpvARWIGADREGLTICDATSAAFALPLDWSKLDVYTFSWQKVLGgEGGHGMAILSpravERLESYTPArpipkffrlTK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 222 ATMLDYAVYakEESMHNTPP--TFAIYVAGLvfKWLKQLGGLERMAEINARKARLLYDAIDESRgfYANPVETRNRSRMN 299
Cdd:PRK03080 233 GGKAIENSF--KGQTINTPSmlTVEDYLDQL--DWANSIGGLDALIARTAANASVLYDWAEKTP--WATPLVADPATRSN 306
|
330
....*....|....*...
gi 1815881133 300 VPFTLADAAMDEAFLKGA 317
Cdd:PRK03080 307 TSVTLDFVDAQAAVDAAA 324
|
|
| PucG |
COG0075 |
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ... |
11-246 |
2.12e-08 |
|
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439845 [Multi-domain] Cd Length: 376 Bit Score: 55.10 E-value: 2.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 11 GPAVLPHVVLEQvqaelldwhgsgMSVMEMSHRGPEFMKIAAEAEQDLRDLLDipANYKILFLQGGATLQFAMVPLNLMR 90
Cdd:COG0075 7 GPTPVPPRVLRA------------MARPMIGHRDPEFVELMDEVRELLKKVFG--TENDVVILTGSGTGAMEAALANLVS 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 91 GHGKASYVQTGIWSK--KAIAEARRFTAVEIAAS-----NEDRYASYVpmQADwqvsPDTAYVHITGNETIGGVEFDfIP 163
Cdd:COG0075 73 PGDKVLVLVNGAFGErwAEIAERYGAEVVVLEVPwgeavDPEEVEEAL--AAD----PDIKAVAVVHNETSTGVLNP-LE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1815881133 164 DLG------DIPLVSDASSHILSKPTDVSRFGL--IYAGAQKNI-GPAGLTLVIVRDDLLGHAPANTAT-----MLDYAV 229
Cdd:COG0075 146 EIGalakehGALLIVDAVSSLGGVPLDMDEWGIdvVVSGSQKCLmLPPGLAFVAVSERALEAIEARKLPsyyldLKLWLK 225
|
250
....*....|....*..
gi 1815881133 230 YAKEESMHNTPPTFAIY 246
Cdd:COG0075 226 YWEKGQTPYTPPVSLLY 242
|
|
| |
