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Conserved domains on  [gi|1822192341|ref|WP_165784196|]
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MULTISPECIES: iron ABC transporter permease [unclassified Klebsiella]

Protein Classification

ABC transporter permease( domain architecture ID 11439550)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
41-520 1.46e-86

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 276.66  E-value: 1.46e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  41 GFVVAVGLDTGWPTIKALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQS 120
Cdd:COG1178    29 LALLLRAFTDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVA 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 121 YAWVSA------------------VPSLHGLSAGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVV 182
Cdd:COG1178   109 LAWIALfgpngllntllralfglePPDIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVT 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 183 LPQLRLAICGGALLVALHLLAEYGLYVMI--RFDTFTTAIYDQFQSTFSGPAANMLAGVLALCCLAILLLESASRGKARY 260
Cdd:COG1178   189 LPLLRPAIAAGALLVFLLCLADFGTPLVLggGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRRY 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 261 ARIGaGAAREQKRLVLGKGAAVGAQLLLLLLVMLAMgVPLLVLCRWLWLGGIDN----------WLHADLWHSLRQTLLL 330
Cdd:COG1178   269 ATVG-GRARRPRRVKLGRWRWLALALCLLLVLLGLL-LPLLALLLWSLTKALDDnltldnyrfvLLDPSLLRALLNSLLL 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 331 GVGGALLTTTCAIPIAWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTIHYA-RPVYQTEVTLFLAYLLMFMPRA 409
Cdd:COG1178   347 ALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLpLLLYGTLAILVLAYVVRFLPFA 426

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 410 LINLRAGIAQAPVELENVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLLSPLGTRTLSTGFWALTS 489
Cdd:COG1178   427 LRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQLAS 506

                         490       500       510
                  ....*....|....*....|....*....|.
gi 1822192341 490 EIDYVAAAPYALLMIVISLPLTAVLYMQSKK 520
Cdd:COG1178   507 SGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
 
Name Accession Description Interval E-value
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
41-520 1.46e-86

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 276.66  E-value: 1.46e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  41 GFVVAVGLDTGWPTIKALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQS 120
Cdd:COG1178    29 LALLLRAFTDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVA 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 121 YAWVSA------------------VPSLHGLSAGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVV 182
Cdd:COG1178   109 LAWIALfgpngllntllralfglePPDIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVT 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 183 LPQLRLAICGGALLVALHLLAEYGLYVMI--RFDTFTTAIYDQFQSTFSGPAANMLAGVLALCCLAILLLESASRGKARY 260
Cdd:COG1178   189 LPLLRPAIAAGALLVFLLCLADFGTPLVLggGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRRY 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 261 ARIGaGAAREQKRLVLGKGAAVGAQLLLLLLVMLAMgVPLLVLCRWLWLGGIDN----------WLHADLWHSLRQTLLL 330
Cdd:COG1178   269 ATVG-GRARRPRRVKLGRWRWLALALCLLLVLLGLL-LPLLALLLWSLTKALDDnltldnyrfvLLDPSLLRALLNSLLL 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 331 GVGGALLTTTCAIPIAWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTIHYA-RPVYQTEVTLFLAYLLMFMPRA 409
Cdd:COG1178   347 ALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLpLLLYGTLAILVLAYVVRFLPFA 426

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 410 LINLRAGIAQAPVELENVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLLSPLGTRTLSTGFWALTS 489
Cdd:COG1178   427 LRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQLAS 506

                         490       500       510
                  ....*....|....*....|....*....|.
gi 1822192341 490 EIDYVAAAPYALLMIVISLPLTAVLYMQSKK 520
Cdd:COG1178   507 SGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 68-239 2.91e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.46  E-value: 2.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  68 LSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWVSAVPSL-------HGLSAGVFLS 140
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLlgwgilpGLGLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 141 VLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGALLVALHLLAEYGLYVMIRFDTFTTAI 220
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170
                  ....*....|....*....
gi 1822192341 221 YDQFQSTFSGPAANMLAGV 239
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAA 179
cysT CHL00187
sulfate transport protein; Provisional
 71-211 4.00e-10

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 60.03  E-value: 4.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  71 TLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYA---------WVSAVPSLHGLS-----AG 136
Cdd:CHL00187   60 TLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTSVAGLTlatvygdngWIGHLLSHLGIQivftkLG 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1822192341 137 VFLSVL-AYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGALLVALHLLAEYGLYVMI 211
Cdd:CHL00187  140 VLLAMIfVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVII 215
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 346-521 4.07e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 59.23  E-value: 4.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 346 AWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTIHYArpVYQTEVTLFLAYLLMFMPRALINLRAGIAQAPVELE 425
Cdd:pfam00528   6 IIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI--LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 426 NVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLL---SPLGTRTLSTGFWALTSEIDYVAAApYALL 502
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswPGLGLLLIEAILGYDYPEIQGPVLA-AALI 162

                         170
                  ....*....|....*....
gi 1822192341 503 MIVISLPLTAVLYMQSKKM 521
Cdd:pfam00528 163 LLLLNLLVDILQRLLDPRV 181
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 90-184 5.02e-09

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 58.54  E-value: 5.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  90 AWLTERTALAG--RQLWSALAVAPLAIPAFVQSYAWV----SAVPSLHGLSAGVFLSVLA----YYPFIYMPVAAVLRRL 159
Cdd:TIGR03262 356 AYLIEKTRGFGllRGVLRFLAILPMAVPGLVLGLGYIfffnAPTNPLNGLYGTMALLVLCtvvhFYTVSHLTAVTALKQI 435

                          90       100
                  ....*....|....*....|....*
gi 1822192341 160 DPTLEDVAASLGTPPWKVFFRVVLP 184
Cdd:TIGR03262 436 DSEFEAVSASLKVPFYKTFLRVTLP 460
 
Name Accession Description Interval E-value
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
41-520 1.46e-86

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 276.66  E-value: 1.46e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  41 GFVVAVGLDTGWPTIKALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQS 120
Cdd:COG1178    29 LALLLRAFTDGLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVA 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 121 YAWVSA------------------VPSLHGLSAGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVV 182
Cdd:COG1178   109 LAWIALfgpngllntllralfglePPDIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVT 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 183 LPQLRLAICGGALLVALHLLAEYGLYVMI--RFDTFTTAIYDQFQSTFSGPAANMLAGVLALCCLAILLLESASRGKARY 260
Cdd:COG1178   189 LPLLRPAIAAGALLVFLLCLADFGTPLVLggGYTTLTTAIYQAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRRY 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 261 ARIGaGAAREQKRLVLGKGAAVGAQLLLLLLVMLAMgVPLLVLCRWLWLGGIDN----------WLHADLWHSLRQTLLL 330
Cdd:COG1178   269 ATVG-GRARRPRRVKLGRWRWLALALCLLLVLLGLL-LPLLALLLWSLTKALDDnltldnyrfvLLDPSLLRALLNSLLL 346

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 331 GVGGALLTTTCAIPIAWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTIHYA-RPVYQTEVTLFLAYLLMFMPRA 409
Cdd:COG1178   347 ALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLpLLLYGTLAILVLAYVVRFLPFA 426

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 410 LINLRAGIAQAPVELENVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLLSPLGTRTLSTGFWALTS 489
Cdd:COG1178   427 LRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQLAS 506

                         490       500       510
                  ....*....|....*....|....*....|.
gi 1822192341 490 EIDYVAAAPYALLMIVISLPLTAVLYMQSKK 520
Cdd:COG1178   507 SGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 61-193 2.03e-18

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 85.16  E-value: 2.03e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  61 RPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWVSAVPSLhGLSAGVFLS 140
Cdd:COG1177    56 DPRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSAL-GLSGGLWGL 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1822192341 141 VLAY----YPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGG 193
Cdd:COG1177   135 ILAHvvftLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAG 191
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 56-237 1.40e-14

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 74.03  E-value: 1.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  56 KALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWV----------- 124
Cdd:COG1176    57 ARLFTDPLYLKVLLRTLWIALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIvllgrngllns 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 125 ---------SAVPSLHGLSAGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGAL 195
Cdd:COG1176   137 lllalglidEPLRLLYTEFAVVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSL 216

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1822192341 196 LVALHLLAEYGLYVMI---RFDTFTTAIYDQFQSTFSGPAANMLA 237
Cdd:COG1176   217 LVFIPALGAFVTPALLgggKVLMIGNLIYQQFLSALNWPLAAALA 261
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 43-211 4.02e-14

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 72.48  E-value: 4.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  43 VVAVGLDTGWPTIKALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSAL---------AVAPLA 113
Cdd:COG0555    31 LVLKAAGLGWAEFWAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALvdlpfalptAVAGIA 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 114 IPAFVQSYAWVSAVPSLHGLS-----AGVFLS-VLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLR 187
Cdd:COG0555   111 LLLLFGPNGWLGQLLAPLGIKvaftpLGIVLAqTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLL 190

                         170       180
                  ....*....|....*....|....
gi 1822192341 188 LAICGGALLVALHLLAEYGLYVMI 211
Cdd:COG0555   191 PALLTGFALAFARALGEFGAVIFI 214
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 68-239 2.91e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.46  E-value: 2.91e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  68 LSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWVSAVPSL-------HGLSAGVFLS 140
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLlgwgilpGLGLPALILA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 141 VLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGALLVALHLLAEYGLYVMIRFDTFTTAI 220
Cdd:cd06261    81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                         170
                  ....*....|....*....
gi 1822192341 221 YDQFQSTFSGPAANMLAGV 239
Cdd:cd06261   161 TGLLLIFAILFPGDLGVAA 179
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 318-520 3.00e-13

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 69.76  E-value: 3.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 318 ADLWHSLRQTLLLGVGGALLTTTCAIPIAWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTihYARPVYQTEVTL 397
Cdd:COG1177    57 PRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLF--SALGLSGGLWGL 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 398 FLAYLLMFMPRALINLRAGIAQAPVELENVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLLSPLGT 477
Cdd:COG1177   135 ILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGV 214

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1822192341 478 RTLSTGFW-ALTSEIDYVAAApYALLMIVISLPLTAVLYMQSKK 520
Cdd:COG1177   215 TTLPVYIYsMIRRGISPEINA-LSTLLILLSLLLLLLAERLRRR 257
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 338-508 1.52e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 60.37  E-value: 1.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 338 TTTCAIPIAWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTIHYARPVYQTEVTLF--LAYLLMFMPRALINLRA 415
Cdd:cd06261    15 ALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPalILALLLIAPFARLIRRA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 416 GIAQAPVELENVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLLSPLGTRTLSTG---FWALTSEID 492
Cdd:cd06261    95 ALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGlllIFAILFPGD 174

                         170
                  ....*....|....*.
gi 1822192341 493 YVAAAPYALLMIVISL 508
Cdd:cd06261   175 LGVAAAVALILLLLSL 190
cysT CHL00187
sulfate transport protein; Provisional
 71-211 4.00e-10

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 60.03  E-value: 4.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  71 TLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYA---------WVSAVPSLHGLS-----AG 136
Cdd:CHL00187   60 TLSMALIAALINGFFGLLIAWVLVRYNFPGKRLLDAAVDLPFALPTSVAGLTlatvygdngWIGHLLSHLGIQivftkLG 139

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1822192341 137 VFLSVL-AYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGALLVALHLLAEYGLYVMI 211
Cdd:CHL00187  140 VLLAMIfVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVII 215
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 346-521 4.07e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 59.23  E-value: 4.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 346 AWLGVRYPRPLFRLLEGCNYITSSLPGIVTALALVTVTIHYArpVYQTEVTLFLAYLLMFMPRALINLRAGIAQAPVELE 425
Cdd:pfam00528   6 IIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI--LGHGILPAIILALLGWAGYARLIRRAALRSLPSDLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 426 NVARSLGRSPARALWSITMRLAAPGAAAGAALVFLGVSNELTATLLL---SPLGTRTLSTGFWALTSEIDYVAAApYALL 502
Cdd:pfam00528  84 EAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswPGLGLLLIEAILGYDYPEIQGPVLA-AALI 162

                         170
                  ....*....|....*....
gi 1822192341 503 MIVISLPLTAVLYMQSKKM 521
Cdd:pfam00528 163 LLLLNLLVDILQRLLDPRV 181
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 298-508 7.53e-10

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 59.76  E-value: 7.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 298 VPLLVLCRWLWLGGIDNWLHA----DLWHSLRQTLLLGVGGALLTTTCAIPIAWLGVRYPRPLFRLLEGCNYITSSLPGI 373
Cdd:COG0555    26 LPLAALVLKAAGLGWAEFWAVltspRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTA 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 374 VTALALVTVtihYARP-------------VYQTEVTLFLAYLLMFMPRALINLRAGIAQAPVELENVARSLGRSPARALW 440
Cdd:COG0555   106 VAGIALLLL---FGPNgwlgqllaplgikVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFR 182

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1822192341 441 SITMRLAAPGAAAGAALVFLGVSNELTATLLLS---PLGTRTLSTGFWALTSEIDYVAAAPYALLMIVISL 508
Cdd:COG0555   183 RVILPLLLPALLTGFALAFARALGEFGAVIFIAgnlPMKTEILPLLIYLKLEEGDYAGATAIALVLLLISF 253
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 90-184 5.02e-09

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 58.54  E-value: 5.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  90 AWLTERTALAG--RQLWSALAVAPLAIPAFVQSYAWV----SAVPSLHGLSAGVFLSVLA----YYPFIYMPVAAVLRRL 159
Cdd:TIGR03262 356 AYLIEKTRGFGllRGVLRFLAILPMAVPGLVLGLGYIfffnAPTNPLNGLYGTMALLVLCtvvhFYTVSHLTAVTALKQI 435

                          90       100
                  ....*....|....*....|....*
gi 1822192341 160 DPTLEDVAASLGTPPWKVFFRVVLP 184
Cdd:TIGR03262 436 DSEFEAVSASLKVPFYKTFLRVTLP 460
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
 62-191 2.11e-08

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 56.80  E-value: 2.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  62 PRVGELLSNTLWLTVLAVPISIVLgvTLAWL--TERTALAGRQLWSALAVAPLAIP--AFVQS-YAWVSAVPSLHGLSAG 136
Cdd:COG4135   352 PGLLEPLGNTLLLALASALIALVL--VLACLeaEARRGRRPGRRALWLLYLPLLVPqiAFLFGlQVLLLRLGLDGTWLAV 429

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1822192341 137 VFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAIC 191
Cdd:COG4135   430 IWAHLVFVLPYVFLSLAGPWRALDPRYAQVAASLGASPWRVFWRVKLPLLLRPIL 484
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 46-239 2.03e-07

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 52.70  E-value: 2.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  46 VGLDTGWPTIKALVFRprvgELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWV- 124
Cdd:PRK15050   57 LGLATYRAVLGSPDFR----GALLTTLQIAFASTAGCLVLGVLLALVLAFVPFPGASLVGRFIDTFVAFPSFLITLAFTf 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 125 ---------SAVPSLHGLSA----------GVFLSVLAYY-PFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLP 184
Cdd:PRK15050  133 lygsagsvnIALQRLFGLEAppldflyspgGVILAEITFYtPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILP 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1822192341 185 QLRLAICGGALLVALHLLAEYGLYVMI---RFDTFTTAIYDQFQSTFSGPAANMLAGV 239
Cdd:PRK15050  213 EAWPALAAGGSLCLLLTLNEFGIVLFTgakDVVTLPVLIYSKAIVDFDYPTACAIAVV 270
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 55-190 3.50e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 52.76  E-value: 3.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  55 IKALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWVS--------- 125
Cdd:TIGR03262  43 FAEYFATPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYlfgnqgllk 122

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1822192341 126 ---AVPSLHGLSAGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAI 190
Cdd:TIGR03262 123 gllGGFSIYGFWGIVIGEVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAKYGL 190
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
68-187 3.85e-07

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 51.67  E-value: 3.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  68 LSNTLWLTVLAVPISIVLGVTLAWLTERtALAGRQLWSALAVAPLAIPAFVQSYAW----------VSAVPSLHGLSAGV 137
Cdd:COG1175    78 LGNTLLFTVVSVPLQLVLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWkwlfnpdyglLNALLGALGLEPIN 156

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1822192341 138 FLS-------------VLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLR 187
Cdd:COG1175   157 WLGdpslalpaviivtVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLR 219
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 52-185 6.46e-07

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 50.53  E-value: 6.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  52 WPTIKALVFRPRVGELLSNTLWLTVLAVPISIVLGVTLAWLTERTALAGRQLW---------SALAVAPLAIpafvqsyA 122
Cdd:COG0600    47 LAALVELLASGELWEHLLASLLRVLLGFALAALLGVPLGLLLGLSRLLRRLLDpllvflrpiPPLALAPLLI-------L 119

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1822192341 123 WVSAvpslhGLSAGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQ 185
Cdd:COG0600   120 WFGI-----GEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPA 177
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
72-206 1.56e-06

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 49.75  E-value: 1.56e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  72 LWLTVL----AVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPA---------FVQSYAWVSAVPSLHGLS---- 134
Cdd:PRK11602   66 IWLTVLialiAVPVNLVFGILLAWLVTRFNFPGRQLLLTLLDIPFAVSPvvaglvyllFYGSNGPLGGWLDEHNLQlmfs 145

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1822192341 135 --AGVFLSVLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGALLVALHLLAEYG 206
Cdd:PRK11602  146 wpGMVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFG 219
modB PRK09421
molybdate ABC transporter permease subunit;
67-184 1.25e-05

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 46.45  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  67 LLSntLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYA-----------------WVSAVPS 129
Cdd:PRK09421   12 LLS--LKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVTGYLllismgrrgfigqwlyeWFGISFA 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1822192341 130 LHGLSAGVFLSVLAYyPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLP 184
Cdd:PRK09421   90 FSWRGAALAAAVMAF-PLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLP 143
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
71-239 2.76e-05

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 45.90  E-value: 2.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  71 TLWLTVLAVPISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQ--SYAWVSAVPSLHGLSAGVFLSVLAY---- 144
Cdd:PRK10971   63 TLLSAFVASIFNAVFGLLMAWILTRYRFPGRTLLDALMDLPFALPTAVAglTLASLFSVNGWYGEWLAKFDIKVTYtwlg 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341 145 ---------YPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGGALLVALHLLAEYGLYVMI---- 211
Cdd:PRK10971  143 iavamaftsIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIagni 222

                         170       180       190
                  ....*....|....*....|....*....|
gi 1822192341 212 --RFDTFTTAIYDQFQStFSGPAANMLAGV 239
Cdd:PRK10971  223 awKTEVTSLMIFVRLQE-FDYPAASAIASV 251
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 62-190 4.83e-04

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 41.60  E-value: 4.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  62 PRVGELLSNTLWLTVLAVPISIVLGVTLAWLtertALAGRQLWSALAVAPL----AIPAFVQSYAWVSAVPSLhGLSAGV 137
Cdd:COG0765    13 PLLLEGLLVTLLLTVLAIVLGLVLGLLLALA----RLSPNPVLRWLATAYVeffrGTPLLVQLFFIYFGLPLL-GIDLSP 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1822192341 138 FLSVL--------AYypfiympVAAVLR----RLDPTLEDVAASLGTPPWKVFFRVVLPQ-LRLAI 190
Cdd:COG0765    88 FVAAVialtlnsaAY-------LAEIVRagiqSVPKGQWEAARALGLSRWQTMRRIILPQaLRIIL 146
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 81-193 2.68e-03

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 40.08  E-value: 2.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  81 ISIVLGVTLAWLTERTALAGRQLWSALAVAPLAIPAFVQSYAWVSAVPS--------------------LHGLSAGVFLS 140
Cdd:PRK10683  112 CCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNngvlnnfllwlgvidqpltiLHTNLAVYIGI 191

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1822192341 141 VLAYYPFIYMPVAAVLRRLDPTLEDVAASLGTPPWKVFFRVVLPQLRLAICGG 193
Cdd:PRK10683  192 VYAYLPFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAG 244
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 82-190 2.71e-03

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 38.82  E-value: 2.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822192341  82 SIVLGVTLAWLTERTAlagRQLWSALAVAPLAIPAFVQSYAWVSAVPSL---HGLSAGVFLSVLAYYPFIYMPVAAVLRR 158
Cdd:pfam00528   1 GIPLGIIAALRRGRRL---DRLLRPLIDLLQALPSFVLAILLVVIAILSilgHGILPAIILALLGWAGYARLIRRAALRS 77

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1822192341 159 LDPTLEDVAASLGTPPWKVFFRVVLPQLRLAI 190
Cdd:pfam00528  78 LPSDLVEAARALGASRWQIFRKIILPNALPPI 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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