|
Name |
Accession |
Description |
Interval |
E-value |
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
115-464 |
6.62e-83 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 261.03 E-value: 6.62e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 115 ISTVTRYSSTLGKDTIYTAVLLDSGNVLRLSEERASFVSVFKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLNQIDVA 194
Cdd:COG5002 51 LLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 195 SPLENETYEEMRPLLSRVEAQQRQLmeqnRELARAENIRREFSANVSHEMKTPLQVISGYAELLAGGKIPQKD-AERFAR 273
Cdd:COG5002 131 LGRLSLRLSALLLGLLLLAAVERDI----TELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADDPEeRREYLE 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 274 IILTESANMTDLINDVLVLSRIDDPVMEnAGKEEVELLSLSHEIVTRFLPLAEKQSVSIR--CLGSSVVVDGNKSLLDQL 351
Cdd:COG5002 207 IILEEAERLSRLVNDLLDLSRLESGELK-LEKEPVDLAELLEEVVEELRPLAEEKGIELEldLPEDPLLVLGDPDRLEQV 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 352 VSNLLSNALKYSDPDGEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAI 431
Cdd:COG5002 286 LTNLLDNAIKYTPEGGTITVSL--------REEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAI 357
|
330 340 350
....*....|....*....|....*....|...
gi 1823255651 432 AKHAAVFHNGTISVESSVGRGSVFTVRIPTEHE 464
Cdd:COG5002 358 VKHIVEAHGGRIWVESEPGKGTTFTITLPLARE 390
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
218-464 |
1.23e-71 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 226.71 E-value: 1.23e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 218 QLMEQNRELARAENIRREFSANVSHEMKTPLQVISGYAELLA-GGKIPQKDAERFARIILTESANMTDLINDVLVLSRID 296
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLdEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 297 DPVMENAgKEEVELLSLSHEIVTRFLPLAEKQ--SVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVg 374
Cdd:COG2205 81 SGKLSLE-LEPVDLAELLEEAVEELRPLAEEKgiRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISA- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 375 ksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKesGGTGLGLAIAKHAAVFHNGTISVESSVGRGSV 454
Cdd:COG2205 159 -------RREGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRGE--GGTGLGLAIVKRIVEAHGGTIWVESEPGGGTT 229
|
250
....*....|
gi 1823255651 455 FTVRIPTEHE 464
Cdd:COG2205 230 FTVTLPLAES 239
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
130-462 |
4.66e-70 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 225.56 E-value: 4.66e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 130 IYTAVLLDSGNVLRLSEERASFVSVFKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLNQIDVASPLENETYEEMRPLL 209
Cdd:COG0642 7 LLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 210 SRVEAQQRQLMEQNRELARAENIRREFSANVSHEMKTPLQVISGYAELLAGGkiPQKDAERFARIILTESANMTDLINDV 289
Cdd:COG0642 87 LLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEE--LDEEQREYLETILRSADRLLRLINDL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 290 LVLSRIDDPVMENAgKEEVELLSLSHEIVTRFLPLAEKQSVSIR--CLGSSVVVDGNKSLLDQLVSNLLSNALKYSDPDG 367
Cdd:COG0642 165 LDLSRLEAGKLELE-PEPVDLAELLEEVVELFRPLAEEKGIELEldLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 368 EVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRskESGGTGLGLAIAKHAAVFHNGTISVES 447
Cdd:COG0642 244 TVTVSV--------RREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSR--RGGGTGLGLAIVKRIVELHGGTIEVES 313
|
330
....*....|....*
gi 1823255651 448 SVGRGSVFTVRIPTE 462
Cdd:COG0642 314 EPGKGTTFTVTLPLA 328
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
225-459 |
7.49e-60 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 198.97 E-value: 7.49e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 225 ELARAENIRREFSANVSHEMKTPLQVISGYAE-LLAGGKIPQKDAERFARIILTESANMTDLINDVLVLSRIDDPVmENA 303
Cdd:TIGR02966 106 RLRRLEQMRRDFVANVSHELRTPLTVLRGYLEtLADGPDEDPEEWNRALEIMLEQSQRMQSLVEDLLTLSRLESAA-SPL 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 304 GKEEVELLSLSHEIVTRFLPLAEKQSVSIRC-LGSSVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVlvgksiappDS 382
Cdd:TIGR02966 185 EDEPVDMPALLDHLRDEAEALSQGKNHQITFeIDGGVDVLGDEDELRSAFSNLVSNAIKYTPEGGTITV---------RW 255
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1823255651 383 EGTP-MAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRI 459
Cdd:TIGR02966 256 RRDGgGAEFSVTDTGIGIAPEHLPRLTERFYRVDKSRSRDTGGTGLGLAIVKHVLSRHHARLEIESELGKGSTFSFIF 333
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
30-464 |
2.32e-49 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 176.13 E-value: 2.32e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 30 IFMALFYLVYEHDEEQRVATIAESAAAFLEDKDTQDSVRILEGQLGQDIRYTLVDPQGNVVFDSGGNVDENHADRPEILE 109
Cdd:COG4251 79 ALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 110 AREKGISTVTRYSSTLGKDTIYTAVLLDSGNVLRLSEERASFVSVFKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLN 189
Cdd:COG4251 159 LLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 190 QIDVASPLENETYEEMRPLLSRVEAQQRQLMEQNRELARAENIRREFSANVSHEMKTPLQVISGYAELL---AGGKIPQk 266
Cdd:COG4251 239 LLLILLLLLLILVLELLELRLELEELEEELEERTAELERSNEELEQFAYVASHDLREPLRKISGFSQLLeedYGDKLDE- 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 267 DAERFARIILTESANMTDLINDVLVLSRIDDPVMEnagKEEVELLSLSHEIVTRFLPLAEKQSVSIRcLGSSVVVDGNKS 346
Cdd:COG4251 318 EGREYLERIRDAAERMQALIDDLLAYSRVGRQELE---FEPVDLNELLEEVLEDLEPRIEERGAEIE-VGPLPTVRGDPT 393
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 347 LLDQLVSNLLSNALKYSDPDGEVVVLVGKSIAPPDSEgtpmayIRVRDNGCGIPLEEQHKIFERFYRVDksRSKESGGTG 426
Cdd:COG4251 394 LLRQVFQNLISNAIKYSRPGEPPRIEIGAEREGGEWV------FSVRDNGIGIDPEYAEKIFEIFQRLH--SRDEYEGTG 465
|
410 420 430
....*....|....*....|....*....|....*...
gi 1823255651 427 LGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTEHE 464
Cdd:COG4251 466 IGLAIVKKIVERHGGRIWVESEPGEGATFYFTLPKAPA 503
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
188-460 |
8.21e-43 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 156.71 E-value: 8.21e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 188 LNQIDVASPLE----NETYEEMR--P-------LLSRVEAQQRQLmeqnrelaraENIRREFSANVSHEMKTPLQVISGY 254
Cdd:PRK11006 156 LKTRDFSRPLTlvlnNGRHLEIRvmPytegqllMVARDVTQMHQL----------EGARRNFFANVSHELRTPLTVLQGY 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 255 AELL----AGGKIPQKdaerfARIILTESAN-MTDLINDVLVLSRI------------DDPVMenagkeeveLLSLSHEI 317
Cdd:PRK11006 226 LEMMqdqpLEGALREK-----ALHTMREQTQrMEGLVKQLLTLSKIeaaptidlnekvDVPMM---------LRVLEREA 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 318 VTrflpLAEKQSVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVGKSiappdSEGtpmAYIRVRDNGC 397
Cdd:PRK11006 292 QT----LSQGKHTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRV-----PQG---AEFSVEDNGP 359
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1823255651 398 GIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK11006 360 GIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
208-464 |
9.69e-43 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 156.83 E-value: 9.69e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 208 LLSRVEAQQRQLMEQNRElarAENIRREFSANVSHEMKTPLQVISGYAELLAGgKIPQKDAERFARIILTESANMTDLIN 287
Cdd:COG5808 219 LLKRKTLLERVIQEINTQ---KLELIGTFAASTAHEIRNPLTSIKGFIQLLQE-KYPELEDQKYFDIIQEEIQRINQIVS 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 288 DVLVLSRiddpvMENAGKEEVELLSLSHEIVTRFLPLAEKQ--SVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDP 365
Cdd:COG5808 295 EFLVLGK-----PTAKKLELDDLNELIEEILSIIDSEANLKniRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 366 DGEVVVLVGksiapPDSEgtpMAYIRVRDNGCGIPLEEQHKIFERFYrvdksRSKEsGGTGLGLAIAKHAAVFHNGTISV 445
Cdd:COG5808 370 GGKLTISIE-----NDDE---KAVIEVIDNGEGIPEDIIDEIFEPFV-----TTKE-GGTGLGLSVCKRIVEMHGGEIDI 435
|
250
....*....|....*....
gi 1823255651 446 ESSVGRGSVFTVRIPTEHE 464
Cdd:COG5808 436 ESEEGKGTTFTIRLPLKKE 454
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
194-464 |
4.20e-42 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 153.08 E-value: 4.20e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 194 ASPLENETYEEMRPLLSRVEAQQRQLMEQNRELARAENIRrEFSANVSHEMKTPLQVISGYAELLAGgKIPQKDAERFAR 273
Cdd:COG3852 97 VSPLRDAEGEGGVLLVLRDITERKRLERELRRAEKLAAVG-ELAAGLAHEIRNPLTGIRGAAQLLER-ELPDDELREYTQ 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 274 IILTESANMTDLINDVLVLSRIDDPVMEnagkeEVELlslsHEIVTRFLPLAE---KQSVSIRC-LGSSV-VVDGNKSLL 348
Cdd:COG3852 175 LIIEEADRLNNLVDRLLSFSRPRPPERE-----PVNL----HEVLERVLELLRaeaPKNIRIVRdYDPSLpEVLGDPDQL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 349 DQLVSNLLSNALKYSDPDGEVVV--LVGKSIAPPDSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKEsGGTG 426
Cdd:COG3852 246 IQVLLNLVRNAAEAMPEGGTITIrtRVERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFT-----TKE-KGTG 319
|
250 260 270
....*....|....*....|....*....|....*...
gi 1823255651 427 LGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTEHE 464
Cdd:COG3852 320 LGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLPLEQA 357
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
141-461 |
7.55e-40 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 149.22 E-value: 7.55e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 141 VLRLSEERASFVSVFKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLNQI-DVASPLENETYEEMrPLLSRVEAqqrql 219
Cdd:PRK11100 163 VLSVGKPNSSMAPFIKRSERRILWAGALLLGIALLIGAGVVWWLNRSIRRLtRYADAVTEGKPVPL-PKLGSSEL----- 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 220 meqnRELARA-ENIRRE---------FSANVSHEMKTPLQVISGYAELLAGGkIPQKDAERFARIILTESANMTDLINDV 289
Cdd:PRK11100 237 ----RELAQAlESMRVKlegkayveqYVQTLTHELKSPLAAIRGAAELLQED-PPPEDRARFTGNILTQSARLQQLIDRL 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 290 LVLSRIddpvmEN----AGKEEVELLSLSHEIVTRFLPLAEKQSVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDP 365
Cdd:PRK11100 312 LELARL-----EQrqelEVLEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 366 DGEVVVLVGKsiappDSEGtpmAYIRVRDNGCGIPLEEQHKIFERFY---RVDKSRSkesgGTGLGLAIAKHAAVFHNGT 442
Cdd:PRK11100 387 GGTITLSAEV-----DGEQ---VALSVEDQGPGIPDYALPRIFERFYslpRPANGRK----STGLGLAFVREVARLHGGE 454
|
330
....*....|....*....
gi 1823255651 443 ISVESSVGRGSVFTVRIPT 461
Cdd:PRK11100 455 VTLRNRPEGGVLATLTLPR 473
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
142-460 |
5.37e-38 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 141.86 E-value: 5.37e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 142 LRLSEERASFVSVFKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLNQIDVASPLENETYEEMRPLLSRVEAQQRQLME 221
Cdd:COG4191 49 LLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAEEELRE 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 222 QNRELARAEnirR-----EFSANVSHEMKTPLQVISGYAELL---AGGKIPQKDAERFARIILTESANMTDLINDVLVLS 293
Cdd:COG4191 129 LQEQLVQSE---KlaalgELAAGIAHEINNPLAAILGNAELLrrrLEDEPDPEELREALERILEGAERAAEIVRSLRAFS 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 294 RIDDPVMEnagkeEVELlslsHEIVTRFLPLAE----KQSVSIRC-LGSSV-VVDGNKSLLDQLVSNLLSNALkysD--- 364
Cdd:COG4191 206 RRDEEERE-----PVDL----NELIDEALELLRprlkARGIEVELdLPPDLpPVLGDPGQLEQVLLNLLINAI---Dame 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 365 --PDGEVVVlvgkSIAPPDsegtPMAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKESG-GTGLGLAIAKHAAVFHNG 441
Cdd:COG4191 274 egEGGRITI----STRREG----DYVVISVRDNGPGIPPEVLERIFEPFFT-----TKPVGkGTGLGLSISYGIVEKHGG 340
|
330
....*....|....*....
gi 1823255651 442 TISVESSVGRGSVFTVRIP 460
Cdd:COG4191 341 RIEVESEPGGGTTFTITLP 359
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
143-465 |
1.88e-37 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 141.64 E-value: 1.88e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 143 RLSEERASFVSVFKSTEPALIVALAAAFVLSV--ALSRLLTHRTVAPLNQIDVASPLENETYEEMRPLLSRVEAQQRQLM 220
Cdd:COG5000 84 ELEERRRYLETILENLPAGVIVLDADGRITLAnpAAERLLGIPLEELIGKPLEELLPELDLAELLREALERGWQEEIELT 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 221 EQNR-----------------------ELARAEniR----REFSANVSHEMKTPLQVISGYAELLA---GGKIP--QKDA 268
Cdd:COG5000 164 RDGRrtllvrasplrddgyvivfdditELLRAE--RlaawGELARRIAHEIKNPLTPIQLSAERLRrklADKLEedREDL 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 269 ERFARIILTESANMTDLINDVLVLSRIDDPVMEnagkeEVELLSLSHEIVTRFLPLAEKQSVSIR--CLGSSVVVDGNKS 346
Cdd:COG5000 242 ERALDTIIRQVDRLKRIVDEFLDFARLPEPQLE-----PVDLNELLREVLALYEPALKEKDIRLEldLDPDLPEVLADRD 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 347 LLDQLVSNLLSNALKYSDPDGEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGTG 426
Cdd:COG5000 317 QLEQVLINLLKNAIEAIEEGGEIEVST--------RREDGRVRIEVSDNGPGIPEEVLERIFEPFF------TTKPKGTG 382
|
330 340 350
....*....|....*....|....*....|....*....
gi 1823255651 427 LGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTEHEG 465
Cdd:COG5000 383 LGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPLAEEA 421
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
7-460 |
9.48e-37 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 140.60 E-value: 9.48e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 7 RLSTTLfRSVFVYSIAILLCFSGIFMALFYLVYEHDEEQR---VATIAESAAAFLEDKDTQDS-----VRILEGQLG--Q 76
Cdd:TIGR01386 1 PRSLTL-RLALLFAAVTALVFALSGFMLYSSLERHFEERDreeLQGKLEQVRRFLRDPADLDEdikrlQEKIDDLLVghS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 77 DIRYTLVDPQGNVVFDSGGN---VDENHADRPeiLEAREKGISTVTRYSSTLGKDtiytAVLLDSGNVLRL----SEERA 149
Cdd:TIGR01386 80 DLALSILNPDGRLLFERAQGaalVPAVAANDA--LLELDQADAKMTHYRSILRSV----AALPGGKGRKPVqitvALDIN 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 150 SFVSVFKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLNQidVASPLENETYEEM--RPLLSRVEAQQRQLM-EQNREL 226
Cdd:TIGR01386 154 AHTHLLDALRKWLILIAVLLVLLTALLGWWITRLGLEPLRR--LSAVAARISPESLdqRLDPSRAPAELRELAqSFNAML 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 227 ARAENIRR---EFSANVSHEMKTPLQVISGYAELLAGgkiPQKDAERFARII---LTESANMTDLINDVLVLSRIDDPVM 300
Cdd:TIGR01386 232 GRLEDAFQrlsQFSADLAHELRTPLTNLLGQTQVALS---QPRTGEEYREVLesnLEELERLSRMVSDMLFLARADNGQL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 301 EnAGKEEVELLSLSHEIVTRFLPLAEKQSVSIRCLGSSVVVdGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVGksiapp 380
Cdd:TIGR01386 309 A-LERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEGLVR-GDPQMFRRAISNLLSNALRHTPDGGTITVRIE------ 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 381 dsEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRgSVFTVRIP 460
Cdd:TIGR01386 381 --RRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRASAESPDGK-TRFILRFP 457
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
348-459 |
5.24e-36 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 128.49 E-value: 5.24e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRskESGGTGL 427
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISL--------RQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSR--EGGGTGL 70
|
90 100 110
....*....|....*....|....*....|..
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRI 459
Cdd:cd00075 71 GLAIVRRIVEAHGGRITVESEPGGGTTFTVTL 102
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
343-460 |
4.96e-35 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 126.22 E-value: 4.96e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 343 GNKSLLDQLVSNLLSNALKYSDPDGEVVVLVGKSIAppdsegtpMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKeS 422
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGD--------HVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRK-I 71
|
90 100 110
....*....|....*....|....*....|....*...
gi 1823255651 423 GGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:smart00387 72 GGTGLGLSIVKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
348-460 |
1.64e-34 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 124.91 E-value: 1.64e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSdPDGEVVVLVGKSiapPDSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGL 427
Cdd:cd16922 1 LRQILLNLLGNAIKFT-EEGEVTLRVSLE---EEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGL 76
|
90 100 110
....*....|....*....|....*....|...
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16922 77 GLAISKKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
216-462 |
3.09e-34 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 133.95 E-value: 3.09e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 216 QRQLMEQNRELARAeNIRREFSANVSHEMKTPLQVISGYAELLAGGKipQKDAERFARIILTESANMTDLINDVLVLSRI 295
Cdd:COG5809 254 RKKLEELLRKSEKL-SVVGELAAGIAHEIRNPLTSLKGFIQLLKDTI--DEEQKTYLDIMLSELDRIESIISEFLVLAKP 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 296 DdpvmenAGK-EEVELLSLSHEIVTRFLPLAEKQSVSIRCLGSSVVVD--GNKSLLDQLVSNLLSNALKYSDPDGEVVVl 372
Cdd:COG5809 331 Q------AIKyEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDIPDilGDENQLKQVFINLLKNAIEAMPEGGNITI- 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 373 vgkSIAPPDSEGTpmaYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRG 452
Cdd:COG5809 404 ---ETKAEDDDKV---VISVTDEGCGIPEERLKKLGEPFY------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKG 471
|
250
....*....|
gi 1823255651 453 SVFTVRIPTE 462
Cdd:COG5809 472 TTFSITLPIK 481
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
14-460 |
1.05e-33 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 132.59 E-value: 1.05e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 14 RSVFVYSIAILLCFSGIFMALFYLVYEHDEEQRVATIAESAAAF---LEDKDTQDSVRI--LEGQLG--QDIRYTLVDPQ 86
Cdd:PRK09835 15 RLTFFISLATIAAFFAFTWIMIHSVKVHFAEQDINDLKQISATLervLNHPDETQARRLmtLEDIVAgySNVLISLADSH 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 87 GNVVFDSGGNVDENH----ADRPEILEAREKGISTVTRYSSTL--GKDTIYTAVLLDSGNVLRLSEERASFVSV------ 154
Cdd:PRK09835 95 GKTVYHSPGAPDLREfvrdAIPDKDARGGEVFLWSGPTPMMPGhgHGHMEHSNWRMIALPVGPLVDGKPIYTLLialsid 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 155 -----FKSTEPALIVALAAAFVLSVALSRLLTHRTVAPLNqiDVASPLENETYEEMRPLL--SRVEAQQRQL-MEQNREL 226
Cdd:PRK09835 175 fhlhyINDLKNKLIMTASVISLLIVFIVLLAVHKGHAPIR--SVSRQIQNITSKDLDVRLdpQTVPIELEQLvLSFNHMI 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 227 ARAENI---RREFSANVSHEMKTPLQVISGYAELLAGGKIPQKDAERFARIILTESANMTDLINDVLVLSRIDDpvmeNA 303
Cdd:PRK09835 253 ERIEDVftrQSNFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADN----NQ 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 304 GKEEVELLSLSHEIVTRF---LPLAEKQSVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSdPDGEVVVLvgkSIapp 380
Cdd:PRK09835 329 LIPEKKMLDLADEVGKVFdffEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYT-PAGEAITV---RC--- 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 381 dSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVgRGSVFTVRIP 460
Cdd:PRK09835 402 -QEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDA-RGTRFVISLP 479
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
192-461 |
1.37e-32 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 126.82 E-value: 1.37e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 192 DVASPLENETYEEMRPLLSRVEAQQRQLMEQnrELARAE--NIRREFSANVSHEMKTPLQVISGYAELLAGgKIPQKDAE 269
Cdd:COG5807 106 EIIYPIYYKDGVILGLITVYRDITKRKEAED--KLLRSEklSVAGELAAGIAHEIRNPLTSIKGFLQLLQE-SREDSERE 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 270 RFARIILTESANMTDLINDVLVLSRiddPVMENagKEEVELLSLSHEIVTRFLPLAEKQSVSIR--CLGSSVVVDGNKSL 347
Cdd:COG5807 183 EYFNIIISEIDRINTIITELLVLSK---PKKFN--FKKLNLNDVLEDVIALLSTEAILKNISIKydLADDEPVINGDKNQ 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVvvlvgkSIAPPDSEGTpmAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKESGgTGL 427
Cdd:COG5807 258 LKQVFINLIKNAIEAMETGGNI------TIKTYVEGDF--VVISVKDEGIGIPEEVLEKIGEPFFT-----TKEEG-TGL 323
|
250 260 270
....*....|....*....|....*....|....
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPT 461
Cdd:COG5807 324 GLSICKKIIEEHNGTIEVESKPGKGTTFTIYLPL 357
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
210-464 |
2.68e-32 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 128.21 E-value: 2.68e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 210 SRVEAQQR----QLMEQNRELARA----ENIRREFSANVSHEMKTPLQVISGYAELLAGGkIPQKDAERFARIiLTESAN 281
Cdd:PRK10549 209 TRVTPTSRdelgRLAQDFNQLASTleknEQMRRDFMADISHELRTPLAVLRGELEAIQDG-VRKFTPESVASL-QAEVGT 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 282 MTDLINDVLVLSriddpvMENAG-----KEEVELLSLSHEIVTRFLPLAEKQSVSIRC-LGSSVVVDGNKSLLDQLVSNL 355
Cdd:PRK10549 287 LTKLVDDLHQLS------LSDEGalayrKTPVDLVPLLEVAGGAFRERFASRGLTLQLsLPDSATVFGDPDRLMQLFNNL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 356 LSNALKYSDPDGEVVVLVGKSiappdsegTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHA 435
Cdd:PRK10549 361 LENSLRYTDSGGSLHISAEQR--------DKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNI 432
|
250 260
....*....|....*....|....*....
gi 1823255651 436 AVFHNGTISVESSVGRGSVFTVRIPTEHE 464
Cdd:PRK10549 433 VEAHNGRIIAAHSPFGGVSITVELPLERD 461
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
218-460 |
1.02e-29 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 121.38 E-value: 1.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 218 QLMEQNRELARAE--NIRREFSANVSHEMKTPLQVISGYAELLAGGKIPQKDaerFARIILTESANMTDLINDVLVLSRI 295
Cdd:COG5805 270 EKKEAEELMARSEklSIAGQLAAGIAHEIRNPLTSIKGFLQLLQPGIEDKEE---YFDIMLSELDRIESIISEFLALAKP 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 296 DdpvmeNAGKEEVELLSLSHEIVTRFLPLAEKQSVSIRCLGSSVV--VDGNKSLLDQLVSNLLSNALKySDPDGEVVVLv 373
Cdd:COG5805 347 Q-----AVNKEKENINELIQDVVTLLETEAILHNIQIRLELLDEDpfIYCDENQIKQVFINLIKNAIE-AMPNGGTITI- 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 374 gkSIAPPDSEgtpmAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKESGgTGLGLAIAKHAAVFHNGTISVESSVGRGS 453
Cdd:COG5805 420 --HTEEEDNS----VIIRVIDEGIGIPEERLKKLGEPFFT-----TKEKG-TGLGLMVSYKIIENHNGTIDIDSKVGKGT 487
|
....*..
gi 1823255651 454 VFTVRIP 460
Cdd:COG5805 488 TFTITLP 494
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
343-463 |
1.09e-29 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 111.69 E-value: 1.09e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 343 GNKSLLDQLVSNLLSNALKYSDPDGEVVVlvgkSIAPPDsegtpMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSkes 422
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITV----TLSEGG-----ELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGG--- 68
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1823255651 423 GGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTEH 463
Cdd:pfam02518 69 GGTGLGLSIVRKLVELLGGTITVESEPGGGTTVTLTLPLAQ 109
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
236-460 |
1.13e-28 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 119.69 E-value: 1.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 236 FSANVSHEMKTPLQVISGYAELLAGGKIPQkDAERFARIILTESANMTDLINDVLVLSRIDDPVMENAGKE----EVell 311
Cdd:PRK10841 450 FLATVSHELRTPLYGIIGNLDLLQTKELPK-GVDRLVTAMNNSSSLLLKIISDILDFSKIESEQLKIEPREfsprEV--- 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 312 sLSHeIVTRFLPLAEKQSVSIRCLGSS---VVVDGNKSLLDQLVSNLLSNALKYSDpDGEVVVLVGksiappdSEGTPMa 388
Cdd:PRK10841 526 -INH-ITANYLPLVVKKRLGLYCFIEPdvpVALNGDPMRLQQVISNLLSNAIKFTD-TGCIVLHVR-------VDGDYL- 594
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1823255651 389 YIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK10841 595 SFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIP 666
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
215-465 |
1.60e-28 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 118.53 E-value: 1.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 215 QQRQLMEQnreLARAENIRR--EFSANVSHEMKTPLQVISGYAELLAGgKIPQKDAERFARIILTESANMTDLINDVLVL 292
Cdd:PRK11360 373 ERKRLQRR---VARQERLAAlgELVAGVAHEIRNPLTAIRGYVQIWRQ-QTSDPPSQEYLSVVLREVDRLNKVIDQLLEF 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 293 SRIDDPVMEnagkeEVELLSLSHEIVTRFLPLAEKQSVSIRCLGSS----VVVDGNksLLDQLVSNLLSNALKYSDPDGE 368
Cdd:PRK11360 449 SRPRESQWQ-----PVSLNALVEEVLQLFQTAGVQARVDFETELDNelppIWADPE--LLKQVLLNILINAVQAISARGK 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 369 VVVLVGKsiappdsEGTPMAYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGTGLGLAIAKHAAVFHNGTISVESS 448
Cdd:PRK11360 522 IRIRTWQ-------YSDGQVAVSIEDNGCGIDPELLKKIFDPFF------TTKAKGTGLGLALSQRIINAHGGDIEVESE 588
|
250
....*....|....*..
gi 1823255651 449 VGRGSVFTVRIPTEHEG 465
Cdd:PRK11360 589 PGVGTTFTLYLPINPQG 605
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
162-460 |
3.09e-27 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 115.51 E-value: 3.09e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 162 LIVALAAAFVLSVALSRLLtHRTVA-PL-NQIDVASPLENETYEEMRP----------------LLSRVEAQQRQL---- 219
Cdd:PRK15347 299 LPFALLILVLLTSVLFLLL-RRYLAkPLwRFVDIINKTGPAALEPRLPenrldelgsiakaynqLLDTLNEQYDTLenkv 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 220 MEQNRELARAE------NIRR-EFSANVSHEMKTPLQVISGYAELLAGGKIPQKDAeRFARIILTESANMTDLINDVLVL 292
Cdd:PRK15347 378 AERTQALAEAKqraeqaNKRKsEHLTTISHEIRTPLNGVLGALELLQNTPLTAEQM-DLADTARQCTLSLLAIINNLLDF 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 293 SRIDDPVMEnAGKEEVELLSLSHE-IVTRFLPlAEKQSVSIRCL-GSSV----VVDGNKslLDQLVSNLLSNALKYSdPD 366
Cdd:PRK15347 457 SRIESGQMT-LSLEETALLPLLDQaMLTIQGP-AQSKSLTLRTFvGAHVplylHLDSLR--LRQILVNLLGNAVKFT-ET 531
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 367 GEVVVLVGKSiappdsegTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDksrsKESGGTGLGLAIAKHAAVFHNGTISVE 446
Cdd:PRK15347 532 GGIRLRVKRH--------EQQLCFTVEDTGCGIDIQQQQQIFTPFYQAD----THSQGTGLGLTIASSLAKMMGGELTLF 599
|
330
....*....|....
gi 1823255651 447 SSVGRGSVFTVRIP 460
Cdd:PRK15347 600 STPGVGSCFSLVLP 613
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
1.36e-25 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 100.35 E-value: 1.36e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVVVLVGKsiappDSEGtpmAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGL 427
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQ-----EESG---ARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGL 72
|
90 100 110
....*....|....*....|....*....|...
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16952 73 GLAIVKHVMSRHDARLLIASELGKGSRFTCLFP 105
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-461 |
1.88e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 97.01 E-value: 1.88e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDgevvVLVGKSIappDSEGTpmaYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGL 427
Cdd:cd16949 1 LARALENVLRNALRYSPSK----ILLDISQ---DGDQW---TITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGL 70
|
90 100 110
....*....|....*....|....*....|....
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPT 461
Cdd:cd16949 71 GLAIAERAIEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
229-463 |
7.05e-24 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 103.53 E-value: 7.05e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 229 AENI------RREFSANVSHEMKTPLQVISGYAELLAGgkipQKDAERFAriILTESANMTDLINDVLVLSRIDDPvmEN 302
Cdd:PRK10604 202 ADNInaliasKKQLIDGIAHELRTPLVRLRYRLEMSDN----LSAAESQA--LNRDIGQLEALIEELLTYARLDRP--QN 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 303 AGK-EEVELLSLSHEIVTRFLPLAEKQSVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVGKSiappd 381
Cdd:PRK10604 274 ELHlSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYAHSRVRVSLLLDGN----- 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 382 segtpMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPT 461
Cdd:PRK10604 349 -----QACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPV 423
|
..
gi 1823255651 462 EH 463
Cdd:PRK10604 424 WH 425
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
338-458 |
7.77e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 95.94 E-value: 7.77e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 338 SVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVgksiappdsEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKS 417
Cdd:cd16940 4 DIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKL---------SADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQ 74
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1823255651 418 RSKesgGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVR 458
Cdd:cd16940 75 NYG---GSGLGLSIVKRIVELHGGQIFLGNAQGGGLEAWVR 112
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
240-465 |
1.77e-23 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 102.70 E-value: 1.77e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 240 VSHEMKTPL---QVisgyAELLAGGKipQKDAERFARIiLTESANMTDLINDVLVLSR----------------IDDPVM 300
Cdd:PRK09470 250 ISHELRTPLtrlQL----ATALLRRR--QGESKELERI-ETEAQRLDSMINDLLVLSRnqqknhleretfkansLWSEVL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 301 ENAgKEEVELLSLSHEIVTrflPLAEkqsvsirclgssVVVDGNKSLLDQLVSNLLSNALKYSDpdGEVVVLVgkSIapp 380
Cdd:PRK09470 323 EDA-KFEAEQMGKSLTVSA---PPGP------------WPINGNPNALASALENIVRNALRYSH--TKIEVAF--SV--- 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 381 DSEGTpmaYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK09470 380 DKDGL---TITVDDDGPGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLP 456
|
....*
gi 1823255651 461 TEHEG 465
Cdd:PRK09470 457 LYKRS 461
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
215-464 |
2.66e-23 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 101.08 E-value: 2.66e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 215 QQRQLMEQNRELARAENIRREFSANvSHEMKTPLQVISGYAELlagGKIpqKDAERFARIILTESANMTDLIndvlvLSR 294
Cdd:COG3290 172 DRTELERLEEELEGVKELAEALRAQ-RHDFRNHLHTISGLLQL---GEY--DEALEYIDEISEELQELIDSL-----LSR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 295 IDDPVMeNAgkeevellslsheIVTRFLPLAEKQSVSIRCLGSSVVVDGNKSLLD--QLVSNLLSNAL----KYSDPDGE 368
Cdd:COG3290 241 IGNPVL-AA-------------LLLGKAARARERGIDLTIDIDSDLPDLPLSDTDlvTILGNLLDNAIeaveKLPEEERR 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 369 VVVLVGksiappDSEGtpMAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKESGGTGLGLAIAKHAAVFHNGTISVESS 448
Cdd:COG3290 307 VELSIR------DDGD--ELVIEVEDSGPGIPEELLEKIFERGFS-----TKLGEGRGLGLALVKQIVEKYGGTIEVESE 373
|
250
....*....|....*.
gi 1823255651 449 VGRGSVFTVRIPTEHE 464
Cdd:COG3290 374 EGEGTVFTVRLPKEGE 389
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
3.17e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 94.07 E-value: 3.17e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVVVLVGKsiappdsegTPMAY-IRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTG 426
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQ---------TPQEVrLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSG 75
|
90 100 110
....*....|....*....|....*....|....
gi 1823255651 427 LGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16946 76 LGLAICHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
3.87e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 93.55 E-value: 3.87e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVVVLVGKSIAPpdseGTPMAYirVRDNGCGIPLEEQHKIFERFYRVDkSRSkESGGTGL 427
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVG----EEWTFY--VRDNGIGIDPEYAEKVFGIFQRLH-SRE-EYEGTGV 72
|
90 100 110
....*....|....*....|....*....|...
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16921 73 GLAIVRKIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
348-460 |
5.75e-23 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 93.33 E-value: 5.75e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVVVLVGKSiappdseGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGL 427
Cdd:cd16925 5 YERVVLNLLSNAFKFTPDGGRIRCILEKF-------RLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGL 77
|
90 100 110
....*....|....*....|....*....|...
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16925 78 GLSIVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
204-462 |
2.15e-21 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 97.88 E-value: 2.15e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 204 EMRPLLSRVEaqqrqlMEQNRELaRAENIRREFSANVSHEMKTPLQVISGYAELLAGGKIPQKDAERFARIILTESANMT 283
Cdd:PRK09959 690 ETRDLIHALE------VERNKAI-NATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLL 762
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 284 DLINDVLVLSRIDDPVMEnAGKEEVELLSLSHEIVTRFLPLAEKQSVSIRCLGS---SVVVDGNKSLLDQLVSNLLSNAL 360
Cdd:PRK09959 763 GLIGEILDVDKIESGNYQ-LQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTfpdHYLVKIDPQAFKQVLSNLLSNAL 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 361 KYSDpdgEVVVLVGKSIAPPDsEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKEsgGTGLGLAIAKHAAVFHN 440
Cdd:PRK09959 842 KFTT---EGAVKITTSLGHID-DNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQ 915
|
250 260
....*....|....*....|..
gi 1823255651 441 GTISVESSVGRGSVFTVRIPTE 462
Cdd:PRK09959 916 GDLSLESHPGIGTTFTITIPVE 937
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
211-463 |
3.46e-21 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 96.67 E-value: 3.46e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 211 RVEAQQRQLmeqNRELARAEniRRE----FSANVSHEMKTPLQVISGYAELLAGGKIPQKDAERFARIILTESANMTDLI 286
Cdd:PRK13837 429 RLETERDAL---ERRLEHAR--RLEavgtLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGARARLII 503
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 287 NDVLVLSRIDDPVMEnagkeEVELLSLSHEIVTRF-LPLAEKQSVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDP 365
Cdd:PRK13837 504 DQILAFGRKGERNTK-----PFDLSELVTEIAPLLrVSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDG 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 366 DGEVVVLVGKSIAP-PD--SEGTPM----AYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGTGLGLAIAKHAAVF 438
Cdd:PRK13837 579 AGRVDISLSRAKLRaPKvlSHGVLPpgryVLLRVSDTGAGIDEAVLPHIFEPFF------TTRAGGTGLGLATVHGIVSA 652
|
250 260
....*....|....*....|....*
gi 1823255651 439 HNGTISVESSVGRGSVFTVRIPTEH 463
Cdd:PRK13837 653 HAGYIDVQSTVGRGTRFDVYLPPSS 677
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
210-463 |
4.82e-21 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 96.51 E-value: 4.82e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 210 SRVEAQQRQLMEQNRELARAENIRRE---FSANVSHEMKTPLQVISGYAELLAGGkiPQKDAER-FARIILTESANMTDL 285
Cdd:PRK11466 418 ARTAELQELVIEHRQARAEAEKASQAksaFLAAMSHEIRTPLYGILGTAQLLADN--PALNAQRdDLRAITDSGESLLTI 495
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 286 INDVLVLSRI----------DDP-----VMENA-----GKEEVELLSLSHEIVTRfLPLAekqsvsirclgssvvVDGNK 345
Cdd:PRK11466 496 LNDILDYSAIeaggknvsvsDEPfeprpLLESTlqlmsGRVKGRPIRLATDIADD-LPTA---------------LMGDP 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 346 SLLDQLVSNLLSNALKYSDpDGEVVVLVGksiappdSEGTPMaYIRVRDNGCGIPLEEQHKIFERFYRVDKSRskesGGT 425
Cdd:PRK11466 560 RRIRQVITNLLSNALRFTD-EGSIVLRSR-------TDGEQW-LVEVEDSGCGIDPAKLAEIFQPFVQVSGKR----GGT 626
|
250 260 270
....*....|....*....|....*....|....*...
gi 1823255651 426 GLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTEH 463
Cdd:PRK11466 627 GLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRV 664
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
193-462 |
1.13e-20 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 95.49 E-value: 1.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 193 VASPLEnetyeemRPLLSRVEAQQRqlMEQNRElaraeNIRREFSANVSHEMKTPLQVISGYAELL------AGGK-IPQ 265
Cdd:PRK10490 638 IANALE-------RLTLTASEEQAR--LASERE-----QLRNALLAALSHDLRTPLTVLFGQAEILtldlasEGSPhARQ 703
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 266 kdaerfARIILTESANMTDLINDVLVLSRIddpvmENAGKE-EVELLSLsHEIVTRFL----PLAEKQSVSIRCLGSSVV 340
Cdd:PRK10490 704 ------ASEIRQQVLNTTRLVNNLLDMARI-----QSGGFNlRKEWLTL-EEVVGSALqmlePGLSGHPINLSLPEPLTL 771
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 341 VDGNKSLLDQLVSNLLSNALKYSDPDGEvvvlvgksIAPPDSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDksrsK 420
Cdd:PRK10490 772 IHVDGPLFERVLINLLENAVKYAGAQAE--------IGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARGN----K 839
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1823255651 421 ESG--GTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTE 462
Cdd:PRK10490 840 ESAipGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLPLE 883
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-460 |
2.43e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 85.94 E-value: 2.43e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 346 SLLDQLVSNLLSNALKYSDPDGEVVVLVGKSIAppdsegtpMAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKESG-G 424
Cdd:cd16943 2 SQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVD--------QVLIEVEDTGSGIDPEILGRIFDPFFT-----TKPVGeG 68
|
90 100 110
....*....|....*....|....*....|....*.
gi 1823255651 425 TGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16943 69 TGLGLSLSYRIIQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
220-460 |
4.13e-20 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 93.76 E-value: 4.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 220 ME-QNREL----ARAEN---IRREFSANVSHEMKTPLQ-VIsGYAELLAggKIP----QKD----AERFARIILTesanm 282
Cdd:PRK11107 272 MEiQNVELdlakKRAQEaarIKSEFLANMSHELRTPLNgVI-GFTRQTL--KTPltptQRDylqtIERSANNLLA----- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 283 tdLINDVLVLSRIDdpvmenAGKEEVE-----LLSLSHEIVTRFLPLA-EKQsvsircLGSSVVVD--------GNKSLL 348
Cdd:PRK11107 344 --IINDILDFSKLE------AGKLVLEnipfsLRETLDEVVTLLAHSAhEKG------LELTLNIDpdvpdnviGDPLRL 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 349 DQLVSNLLSNALKYSDpDGEVVVLVGKsiapPDSEGTPMAY-IRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGL 427
Cdd:PRK11107 410 QQIITNLVGNAIKFTE-SGNIDILVEL----RALSNTKVQLeVQIRDTGIGISERQQSQLFQAFRQADASISRRHGGTGL 484
|
250 260 270
....*....|....*....|....*....|...
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK11107 485 GLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
230-460 |
1.89e-19 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 91.54 E-value: 1.89e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 230 ENIRRE---FSANVSHEMKTPLQVISGYAELLAGGKIpqkDAER-----------------FARII------------LT 277
Cdd:PRK11091 277 EKASRDkttFISTISHELRTPLNGIVGLSRILLDTEL---TAEQrkylktihvsaitlgniFNDIIdmdkmerrklqlDN 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 278 ESANMTDLINDVLVLSRIddpVMENAGkeevelLSLSHEivtRFLPLAEKqsvsirclgssVVVDGNKslLDQLVSNLLS 357
Cdd:PRK11091 354 QPIDFTDFLADLENLSGL---QAEQKG------LRFDLE---PLLPLPHK-----------VITDGTR--LRQILWNLIS 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 358 NALKYSdPDGEVVVLVGksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRV-DKSRSKESGGTGLGLAIAKHAA 436
Cdd:PRK11091 409 NAVKFT-QQGGVTVRVR-------YEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVkDSHGGKPATGTGIGLAVSKRLA 480
|
250 260
....*....|....*....|....
gi 1823255651 437 VFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK11091 481 QAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-460 |
1.77e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 80.51 E-value: 1.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 353 SNLLSNALKYSDPDGEVVVLVGKSiappdsegTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRskESGGTGLGLAIA 432
Cdd:cd16923 6 SNLLSNAIKYSPENTRIYITSFLT--------DDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSR--NTEGAGLGLSIA 75
|
90 100
....*....|....*....|....*...
gi 1823255651 433 KHAAVFHNGTISVESSvGRGSVFTVRIP 460
Cdd:cd16923 76 KAIIELHGGSASAEYD-DNHDLFKVRLP 102
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-459 |
9.02e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 79.09 E-value: 9.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 343 GNKSLLDQLVSNLLSNALKYSDpDGEvvvLVGKSIappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKES 422
Cdd:cd16947 16 ANTEALQRILKNLISNAIKYGS-DGK---FLGMTL----REDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSAK 87
|
90 100 110
....*....|....*....|....*....|....*..
gi 1823255651 423 GGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRI 459
Cdd:cd16947 88 QGNGLGLTITKRLAESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
179-458 |
1.80e-17 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 84.32 E-value: 1.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 179 LLTHRTVAPLNQI---------DVASPLENETY-EEMRPLlsrVEAQQrQLMEQNRELARAEnirREFSANVSHEMKTPL 248
Cdd:PRK10337 180 VLLGRELAPLKKLalalrmrdpDSETPLNATGVpSEVRPL---VEALN-QLFARTHAMMVRE---RRFTSDAAHELRSPL 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 249 QVISGYAELlagGKIPQKDAERFARIILTESANM---TDLINDVLVLSRIDDpvMEN-AGKEEVELLSLSHEIVTRFLPL 324
Cdd:PRK10337 253 AALKVQTEV---AQLSDDDPQARKKALLQLHAGIdraTRLVDQLLTLSRLDS--LDNlQDVAEIPLEDLLQSAVMDIYHT 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 325 AEKQSVSIRCL--GSSVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVGKSiappdsegtpmaYIRVRDNGCGIPLE 402
Cdd:PRK10337 328 AQQAGIDVRLTlnAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNAR------------NFTVRDNGPGVTPE 395
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 1823255651 403 EQHKIFERFYRvdkSRSKESGGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVR 458
Cdd:PRK10337 396 ALARIGERFYR---PPGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVS 448
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
8.37e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 75.93 E-value: 8.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPDGEVVVLVGKSiappdsegtpMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESGGTGL 427
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGG----------RLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGL 70
|
90 100 110
....*....|....*....|....*....|...
gi 1823255651 428 GLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16939 71 GLAIVHRVALWHGGHVECDDSELGGACFRLTWP 103
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
198-460 |
9.34e-17 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 81.54 E-value: 9.34e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 198 ENETyeemrpLLSRVEAQQRQLmeqnrelaraenirrefsANVSHEMKTPLQVISGYAELLAGGKIPQKDAERFARII-L 276
Cdd:PRK09303 140 ENET------LLEQLKFKDRVL------------------AMLAHDLRTPLTAASLALETLELGQIDEDTELKPALIEqL 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 277 TESAN-----MTDLINDVLVLSR-IDDPVMENAgkEEVELLSLSHEIVTRFLPLAEKQSVSIRclgSSVVVD-----GNK 345
Cdd:PRK09303 196 QDQARrqleeIERLITDLLEVGRtRWEALRFNP--QKLDLGSLCQEVILELEKRWLAKSLEIQ---TDIPSDlpsvyADQ 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 346 SLLDQLVSNLLSNALKYSDPDGEVVVLVGKSIappdsegTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKEsgGT 425
Cdd:PRK09303 271 ERIRQVLLNLLDNAIKYTPEGGTITLSMLHRT-------TQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDEGTE--GY 341
|
250 260 270
....*....|....*....|....*....|....*
gi 1823255651 426 GLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK09303 342 GIGLSVCRRIVRVHYGQIWVDSEPGQGSCFHFTLP 376
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
214-460 |
5.20e-16 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 79.83 E-value: 5.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 214 AQQRQLMEqnRELARAENIRR--EFSANVSHEMKTPLQVISGYAELLAGGKIPQKDAERFARIILTESANMTDLINDVLV 291
Cdd:PRK10364 218 LRSRQLLQ--DEMKRKEKLVAlgHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLE 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 292 LSRIDD----PVMENAgkeevellslsheIVTRFLPL----AEKQSVSIRCLGSSVV----VDGNKslLDQLVSNLLSNA 359
Cdd:PRK10364 296 LVKPTHlalqAVDLND-------------LINHSLQLvsqdANSREIQLRFTANDTLpeiqADPDR--LTQVLLNLYLNA 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 360 LKYSDPDGEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGTGLGLAIAKHAAVFH 439
Cdd:PRK10364 361 IQAIGQHGVISVTA--------SESGAGVKISVTDSGKGIAADQLEAIFTPYF------TTKAEGTGLGLAVVHNIVEQH 426
|
250 260
....*....|....*....|.
gi 1823255651 440 NGTISVESSVGRGSVFTVRIP 460
Cdd:PRK10364 427 GGTIQVASQEGKGATFTLWLP 447
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
161-452 |
1.27e-15 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 78.09 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 161 ALIVALAAAFVLSVALSRLLTHRTVAPLNQIDvaSPLENETYEEMRPL-----LSRVEAQQRQLmeqNRELARAEN-IRR 234
Cdd:PRK10755 62 SLLVPSLVMVSLTLLICFQAVRWITRPLAELQ--KELEARTADNLTPIaihssTLEIEAVTSAL---NQLVSRLTStLDQ 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 235 E--FSANVSHEMKTPLQVISGYAELLAGGKIPQKDAeRFARIiltesANMTDLINDVLVLSRiddpvmenAGKEEV---- 308
Cdd:PRK10755 137 ErlFTADVAHELRTPLAGIRLHLELLEKQHHIDVAP-LIARL-----DQMMHTVEQLLQLAR--------AGQSFSsghy 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 309 ELLSLSHEIVtrfLPLAEK---------QSVSIRCLGSSVVVDGNKSLLDQLVSNLLSNALKYSDPDGEVVVLVgksiap 379
Cdd:PRK10755 203 QTVKLLEDVI---LPSQDElsemleqrqQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKL------ 273
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1823255651 380 pdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDkSRskeSGGTGLGLAIAKHAAVFHNGTISVESSVGRG 452
Cdd:PRK10755 274 --SQEDGGAVLAVEDEGPGIDESKCGELSKAFVRMD-SR---YGGIGLGLSIVSRITQLHHGQFFLQNRQERS 340
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
230-294 |
2.51e-15 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 70.32 E-value: 2.51e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1823255651 230 ENIRREFSANVSHEMKTPLQVISGYAELLAGGKIPQKDAERFARIILTESANMTDLINDVLVLSR 294
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
4.76e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 70.56 E-value: 4.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDpdGEVVVlvgksiappDSEGTPM-AYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSkeSGGTG 426
Cdd:cd16950 1 LKRVLSNLVDNALRYGG--GWVEV---------SSDGEGNrTRIQVLDNGPGIAPEEVDELFQPFYRGDNARG--TSGTG 67
|
90 100 110
....*....|....*....|....*....|....
gi 1823255651 427 LGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16950 68 LGLAIVQRISDAHGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-460 |
1.86e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 69.24 E-value: 1.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 352 VSNLLSNALKYSDPDGEVVVLVGKSIAPPDSEgtpmAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKESGGTGLGLAI 431
Cdd:cd16915 5 VGNLIDNALDALAATGAPNKQVEVFLRDEGDD----LVIEVRDTGPGIAPELRDKVFERGVS-----TKGQGERGIGLAL 75
|
90 100
....*....|....*....|....*....
gi 1823255651 432 AKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16915 76 VRQSVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
233-298 |
2.09e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 67.62 E-value: 2.09e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1823255651 233 RREFSANVSHEMKTPLQVISGYAELLAGGKIPQkDAERFARIILTESANMTDLINDVLVLSRIDDP 298
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGYLELLRDEKLDE-EQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
233-298 |
2.13e-14 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 67.59 E-value: 2.13e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1823255651 233 RREFSANVSHEMKTPLQVISGYAELLAGGKIPQKDAErFARIILTESANMTDLINDVLVLSRIDDP 298
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGYLELLLDTELSEEQRE-YLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
230-462 |
8.95e-14 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 73.02 E-value: 8.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 230 ENIRREFSANVSHEMKTPLQVISGYAEL-------LAGGKIpqKDAERFARII-------------LTESANMTDLINDV 289
Cdd:PRK09467 226 EDDRTLLMAGVSHDLRTPLTRIRLATEMmseedgyLAESIN--KDIEECNAIIeqfidylrtgqemPMEMADLNALLGEV 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 290 lVLSriddpvmENAGKEEVElLSLSHEIVTrflplAEKQSVSIRclgssvvvdgnkslldQLVSNLLSNALKYSdpDGEV 369
Cdd:PRK09467 304 -IAA-------ESGYEREIE-TALQPGPIE-----VPMNPIAIK----------------RALANLVVNAARYG--NGWI 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 370 VVLVGKSiappdsegTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSkeSGGTGLGLAIAKHAAVFHNGTISVESSV 449
Cdd:PRK09467 352 KVSSGTE--------GKRAWFQVEDDGPGIPPEQLKHLFQPFTRGDSARG--SSGTGLGLAIVKRIVDQHNGKVELGNSE 421
|
250
....*....|...
gi 1823255651 450 GRGSVFTVRIPTE 462
Cdd:PRK09467 422 EGGLSARAWLPLT 434
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-445 |
6.13e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 64.79 E-value: 6.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 347 LLDQLVSNLLSNALKYSDPDGEVVVLVGKsiappDSEGtpmAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKESgGTG 426
Cdd:cd16945 4 LLRQAINNLLDNAIDFSPEGGLIALQLEA-----DTEG---IELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQK-STG 74
|
90
....*....|....*....
gi 1823255651 427 LGLAIAKHAAVFHNGTISV 445
Cdd:cd16945 75 LGLAFVQEVAQLHGGRITL 93
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
1.04e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 64.52 E-value: 1.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDPD-GEVVVLVGksiappdsEGTPMAYIRVRDNGCGIPLEEQHKIFERFYrVDKSRSKESG-GT 425
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDtGRITVSAM--------PTGKMVTISVEDEGPGIPQEKLESIFDRFY-TERPANEAFGqHS 71
|
90 100 110
....*....|....*....|....*....|....*....
gi 1823255651 426 GLGLAIAKHAAVFHNGTISVES----SVGRGSVFTVRIP 460
Cdd:cd16953 72 GLGLSISRQIIEAHGGISVAENhnqpGQVIGARFTVQLP 110
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-460 |
7.95e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 61.92 E-value: 7.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 352 VSNLLSNALKYSDPDGEVVVLVGKsiappDSEGTpmaYIRVRDNGCGIPLEEQHKIFERFYRVDKSRsKESGGTGLGLAI 431
Cdd:cd16948 10 IGQIVSNALKYSKQGGKIEIYSET-----NEQGV---VLSIKDFGIGIPEEDLPRVFDKGFTGENGR-NFQESTGMGLYL 80
|
90 100
....*....|....*....|....*....
gi 1823255651 432 AKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16948 81 VKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
194-460 |
8.22e-12 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 66.26 E-value: 8.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 194 ASPL-ENETYEEMRPLlsrveAQQRQL-MEQN--------RELARAenirrefsanVSHEMKTPLQVISGYAELLAGGkI 263
Cdd:PRK11073 96 AQRLpEGMILLEMAPM-----DNQRRLsQEQLqhaqqvaaRDLVRG----------LAHEIKNPLGGLRGAAQLLSKA-L 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 264 PQKDAERFARIILTESANMTDLINDVLVLSRIDDPVMENAgkeevellslsHEIVTRFlplaeKQSVSIRCLGSSVVV-D 342
Cdd:PRK11073 160 PDPALTEYTKVIIEQADRLRNLVDRLLGPQRPGTHVTESI-----------HKVAERV-----VQLVSLELPDNVRLIrD 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 343 GNKSL---------LDQLVSNLLSNALKYSDPDGEVVVLVGKSIAPPDSEGTP---MAYIRVRDNGCGIPLEEQHKIFer 410
Cdd:PRK11073 224 YDPSLpelahdpdqIEQVLLNIVRNALQALGPEGGTITLRTRTAFQLTLHGERyrlAARIDIEDNGPGIPPHLQDTLF-- 301
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1823255651 411 fYRVDKSRSkesGGTGLGLAIAKHAAVFHNGTISVESSVGRgSVFTVRIP 460
Cdd:PRK11073 302 -YPMVSGRE---GGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLP 346
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-459 |
2.51e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 60.17 E-value: 2.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 344 NKSLLDQLVSNLLSNALKYSDPDGEVVVLVGKsiappDSEgtpMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSKeSG 423
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYD-----EEE---YLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRS-GG 71
|
90 100 110
....*....|....*....|....*....|....*.
gi 1823255651 424 GTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRI 459
Cdd:cd16975 72 HYGMGLYIAKNLVEKHGGSLIIENSQKGGAEVTVKI 107
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
2.64e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 60.10 E-value: 2.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSD--PDGEVVVLVGKSIAPPDsegtpMAYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGT 425
Cdd:cd16920 1 IQQVLINLVRNGIEAMSegGCERRELTIRTSPADDR-----AVTISVKDTGPGIAEEVAGQLFDPFY------TTKSEGL 69
|
90 100 110
....*....|....*....|....*....|....*
gi 1823255651 426 GLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16920 70 GMGLSICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-460 |
4.31e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 59.72 E-value: 4.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNALKYSDP-DGEVVvlvgksIAPPDSEGTPMAYIRVR--------DNGCGIPLEEQHKIFERFYrvdksr 418
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGsGGEII------LRTRTQRQVTLGHPRHRlalrvsviDNGPGIPPDLQDTIFYPMV------ 68
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1823255651 419 SKESGGTGLGLAIAKHAAVFHNGTISVESSVGRgSVFTVRIP 460
Cdd:cd16918 69 SGRENGTGLGLAIAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-459 |
6.60e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 59.95 E-value: 6.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 343 GNKSLLDQLVSNLLSNALKYSDPDGEVVVlvgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSkes 422
Cdd:cd16954 33 GERNDLMELLGNLLDNACKWCLEFVEVTA----------RQTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQRP--- 99
|
90 100 110
....*....|....*....|....*....|....*..
gi 1823255651 423 gGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRI 459
Cdd:cd16954 100 -GQGLGLAIAKEIVEQYGGELSLSDSPLGGARFEVVF 135
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
240-459 |
1.73e-09 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 59.68 E-value: 1.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 240 VSHEMKTPLQVISGYAELLAGG-KIPQKDAERFARI---ILTESANMTDLINDVLVLSRiddpvmenagKEEVE--LLSL 313
Cdd:PRK13557 170 IAHDFNNLLQVMSGYLDVIQAAlSHPDADRGRMARSvenIRAAAERAATLTQQLLAFAR----------KQRLEgrVLNL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 314 ShEIVTRFLPLAEkqsvsiRCLGSSVVVDgnKSLLDQL-------------VSNLLSNAlKYSDPDGEVVVLV--GKSIA 378
Cdd:PRK13557 240 N-GLVSGMGELAE------RTLGDAVTIE--TDLAPDLwncridptqaevaLLNVLINA-RDAMPEGGRVTIRtrNVEIE 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 379 PPDSEG----TPMAY--IRVRDNGCGIPLEEQHKIFERFYrvdksRSKESG-GTGLGLAIAKHAAVFHNGTISVESSVGR 451
Cdd:PRK13557 310 DEDLAMyhglPPGRYvsIAVTDTGSGMPPEILARVMDPFF-----TTKEEGkGTGLGLSMVYGFAKQSGGAVRIYSEVGE 384
|
....*...
gi 1823255651 452 GSvfTVRI 459
Cdd:PRK13557 385 GT--TVRL 390
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
348-457 |
7.15e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 53.23 E-value: 7.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 348 LDQLVSNLLSNAL----KYSDP--DGEVVVLVGKsiappdsegtpmAYIRVRDNGCGIPLEEQHKIFERFYRvdksrSKE 421
Cdd:cd16976 1 IQQVLMNLLQNALdamgKVENPriRIAARRLGGR------------LVLVVRDNGPGIAEEHLSRVFDPFFT-----TKP 63
|
90 100 110
....*....|....*....|....*....|....*..
gi 1823255651 422 SG-GTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTV 457
Cdd:cd16976 64 VGkGTGLGLSISYGIVEEHGGRLSVANEEGAGARFTF 100
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
354-460 |
1.19e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 57.23 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 354 NLLSNALKYSD--PDGEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQHKIFERFYrvdksrSKESGGTGLGLAI 431
Cdd:PRK11086 440 NLIENALEAVGgeEGGEISVSL--------HYRNGWLHCEVSDDGPGIAPDEIDAIFDKGY------STKGSNRGVGLYL 505
|
90 100
....*....|....*....|....*....
gi 1823255651 432 AKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:PRK11086 506 VKQSVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
10-463 |
5.97e-08 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 54.91 E-value: 5.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 10 TTLFRSVFVYSIAILLCFSGIFMALFYLVYEHDEEQRVATIAESAAAFLEDKDTQDSVRILEGQLGQDIRYTLVDPQGNV 89
Cdd:COG3920 70 ALAAAVGAAAALLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAEL 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 90 VFDSGGNVDENHADRPEILEAREKGISTVTRYSSTLGKDTIYTAVLLDSGNVLRL--SEERASFVSVFKSTEPALIVALA 167
Cdd:COG3920 150 AVALAELAAALLLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLalELLLALLLLLLLLLALLLVLLAA 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 168 AAFVLSVALSRLLTHRTVAPLNQIDVASPLENETYEEMRPLLSRVEAQQRQLMEQNRELARAENIRREFSANVSHEMKTP 247
Cdd:COG3920 230 LLRLRAAVLEELERRRRARGLGRLLLLLLLLLLLLRALLLLAAGIRLVITERKRAEEELEASLEEKELLLRELHHRVKNN 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 248 LQVISGYAELLAGgKIPQKDAERFARiiltesanmtDLINDVLVLSRIDDPVMENAGKEEVELLSLSHEIVTRFLPLAEK 327
Cdd:COG3920 310 LQVVSSLLRLQAR-RADDPEAREALE----------ESQNRIQALALVHELLYQSEDWEGVDLRDYLRELLEPLRDSYGG 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 328 QSVSIRCLGSSVVVDGNKSL-LDQLVSNLLSNALKY---SDPDGEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEe 403
Cdd:COG3920 379 RGIRIELDGPDVELPADAAVpLGLILNELVTNALKHaflSGEGGRIRVSW--------RREDGRLRLTVSDNGVGLPED- 449
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 404 qhkiferfyrVDKSRSKesggtGLGLAIAKHAAVFHNGTISVESSvgRGSVFTVRIPTEH 463
Cdd:COG3920 450 ----------VDPPARK-----GLGLRLIRALVRQLGGTLELDRP--EGTRVRITFPLAE 492
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-460 |
9.06e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 50.23 E-value: 9.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 344 NKSLLDQLVSNLLSNALK----YSDPDGEVVVLVgksiappDSEGTPMAYIRVRDNGCGIPLEEQHKIFERfYRVDKSRs 419
Cdd:cd16944 1 DTTQISQVLTNILKNAAEaiegRPSDVGEVRIRV-------EADQDGRIVLIVCDNGKGFPREMRHRATEP-YVTTRPK- 71
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1823255651 420 kesgGTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16944 72 ----GTGLGLAIVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
213-454 |
9.54e-08 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 54.31 E-value: 9.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 213 EAQQRQLMEQNRELARAENIRREFSANV-------SHEMKTPLQVISGYAeLLAGGKIPQKDAERFARIILTES---ANM 282
Cdd:COG4192 406 EIEERKRIEKNLRQTQDELIQAAKMAVVgqtmtslAHELNQPLNAMSMYL-FSAKKALEQENYAQLPTSLDKIEgliERM 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 283 TDLINDVLVLSRiddpvmenagKEEVELLSLS-HEIVTRFLPLAEKQSVSIRC---LGSSVVVDGNKSLLDQLVSNLLSN 358
Cdd:COG4192 485 DKIIKSLRQFSR----------KSDTPLQPVDlRQVIEQAWELVESRAKPQQItlhIPDDLMVQGDQVLLEQVLVNLLVN 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 359 ALKYSDPDGEVVVLVGKSiappdsegTPMAYIRVRDNGCGIPLEEqhKIFERFYrvdksrSKESGGTGLGLAIAKHAAVF 438
Cdd:COG4192 555 ALDAVATQPQISVDLLSN--------AENLRVAISDNGNGWPLVD--KLFTPFT------TTKEVGLGLGLSICRSIMQQ 618
|
250
....*....|....*.
gi 1823255651 439 HNGTISVESSVGRGSV 454
Cdd:COG4192 619 FGGDLYLASTLERGAM 634
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
351-463 |
9.94e-07 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 50.99 E-value: 9.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 351 LVSNLLSNALKYS--DPDGEVVVLVGKSiappdSEGTPMAyIRVRDNGCGIPLEEQHKIFERFYrvdKSRSKESGGTGLG 428
Cdd:PRK15053 436 IVGNLLDNAFEASlrSDEGNKIVELFLS-----DEGDDVV-IEVADQGCGVPESLRDKIFEQGV---STRADEPGEHGIG 506
|
90 100 110
....*....|....*....|....*....|....*
gi 1823255651 429 LAIAKHAAVFHNGTISVESSVGRGSVFTVRIPTEH 463
Cdd:PRK15053 507 LYLIASYVTRCGGVITLEDNDPCGTLFSIFIPKVK 541
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
161-464 |
3.27e-06 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 49.25 E-value: 3.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 161 ALIVALAAAFVLSVALSRLLTHRTVAPLNQIDVA---------SPLENETYEEMRPL---LSRVEAQQRQLMEQNRELAR 228
Cdd:COG2972 158 LILLIILLLLLLALLLSYLLSRSITRPIKRLKKAmkkvekgdlVRLEVSGNDEIGILarsFNEMVERIKELIEEVYELEL 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 229 AEN----------IRREFSANVshemktpLQVISGYAEllaggkipQKDAERFARIILtesaNMTDLINDVLVLSRIDDP 298
Cdd:COG2972 238 EKKeaelkalqaqINPHFLFNT-------LNSIRWLAE--------LEDPEEAEEMLE----ALSKLLRYSLSKGDELVT 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 299 VmenagKEEVELLS--LSHEIVtRFlplAEKQSVSIRClgssvvvdgNKSLLDQLV-----SNLLSNALKY----SDPDG 367
Cdd:COG2972 299 L-----EEELELIKsyLEIQKL-RF---GDRLEVEIEI---------DEELLDLLIpklilQPLVENAIEHgiepKEGGG 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 368 EVVVLVGKsiappdsEGTpMAYIRVRDNGCGIPLEEQHKIFERFyrvdksrSKESGGTGLGLAIAKHAAVFHNG---TIS 444
Cdd:COG2972 361 TIRISIRK-------EGD-RLVITVEDNGVGMPEEKLEKLLEEL-------SSKGEGRGIGLRNVRERLKLYYGeeyGLE 425
|
330 340
....*....|....*....|
gi 1823255651 445 VESSVGRGSVFTVRIPTEHE 464
Cdd:COG2972 426 IESEPGEGTTVTIRIPLEEE 445
|
|
| sCache_like |
pfam16736 |
Single Cache-like; This entry represents the N-terminal Cache-like domain of the alkaline ... |
39-146 |
3.28e-06 |
|
Single Cache-like; This entry represents the N-terminal Cache-like domain of the alkaline phosphatase synthesis sensor protein PhoR. It covers part of the PAS-like fold that share a central five-stranded beta- sheet of identical topology to other PAS domains.
Pssm-ID: 407005 Cd Length: 114 Bit Score: 45.84 E-value: 3.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 39 YEHDEEQRVATIAESAAAFLEDKDTQDSV--RILEgQLGQ--DIRYTLVDPQGNVVFDSGGNVD--ENHADRPEILEARE 112
Cdd:pfam16736 1 YVEKLEERMEKEAKLLASLLENENLDAAQnkTVLE-EASEklDARITIIDADGKVLYDTGGETEdaEHEAIIQELLSGEE 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 1823255651 113 KGistVTRYSSTLGKDTIYTAV-LLDSGNV---LRLSE 146
Cdd:pfam16736 80 LQ---EVRVITTDEDDLLYYAVpIQKEGEQegyILLSS 114
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
354-448 |
6.39e-06 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 48.48 E-value: 6.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 354 NLLSNALKYSDPDGEVVVLVGKSiappdsegtpMAYIRVRDNGCGIPLEEQHKIFERFYRVDKSRSkesgGTGLGLAIAK 433
Cdd:PRK10815 385 NVLDNACKYCLEFVEISARQTDE----------HLHIVVEDDGPGIPESKRELIFDRGQRADTLRP----GQGLGLSVAR 450
|
90
....*....|....*
gi 1823255651 434 HAAVFHNGTISVESS 448
Cdd:PRK10815 451 EITEQYEGKISAGDS 465
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
390-460 |
1.26e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 44.29 E-value: 1.26e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1823255651 390 IRVRDNGCGIPLEEQHKIFERFYrvdksRSKESG-GTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16919 50 LEVSDTGSGMPAEVLRRAFEPFF-----TTKEVGkGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
211-464 |
7.47e-05 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 44.22 E-value: 7.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 211 RVEAQQRQLMEQNRELARAEnIRREFSA----NVSHEmktpLQVISGYAELLAggKIPQKDAERFARIIltesANMTDLI 286
Cdd:COG4585 33 ERAAELERELAARAEEAREE-ERRRIARelhdGVGQS----LSAIKLQLEAAR--RLLDADPEAAREEL----EEIRELA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 287 NDVL-----VLSRIDDPVMENAGkeevellsLSHEIVTRFLPLAEKQSVSIRclgssVVVDGNKSLLDQLVSN------- 354
Cdd:COG4585 102 REALaelrrLVRGLRPPALDDLG--------LAAALEELAERLLRAAGIRVE-----LDVDGDPDRLPPEVELalyrivq 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 355 -LLSNALKYSDPDgEVVVLVgksiappdSEGTPMAYIRVRDNGCGIPLEEQhkiferfyrvdksrskesGGTGLGLAIAK 433
Cdd:COG4585 169 eALTNALKHAGAT-RVTVTL--------EVDDGELTLTVRDDGVGFDPEAA------------------PGGGLGLRGMR 221
|
250 260 270
....*....|....*....|....*....|.
gi 1823255651 434 HAAVFHNGTISVESSVGRGSVFTVRIPTEHE 464
Cdd:COG4585 222 ERAEALGGTLTIGSAPGGGTRVRATLPLAAA 252
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
424-460 |
4.86e-04 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 41.03 E-value: 4.86e-04
10 20 30
....*....|....*....|....*....|....*..
gi 1823255651 424 GTGLGLAIAKHAAVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16916 142 GRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HATPase_LytS-like |
cd16957 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-460 |
6.25e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis LytS and Staphylococcus aureus LytS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis LytS, a HK of the two-component system (TCS) LytS-LytR needed for growth on pyruvate, and Staphylococcus aureus LytS-LytR TCS involved in the adaptation of S. aureus to cationic antimicrobial peptides. Proteins having this HATPase domain also contain a histidine kinase domain (His-kinase), and a GAF sensor domain; most contain a DUF3816 domain.
Pssm-ID: 340433 [Multi-domain] Cd Length: 106 Bit Score: 39.33 E-value: 6.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 347 LLDQLVSNLLSNALKYSDPDGEVVVLVGKSiappdsegTPMAYIRVRDNGCGIPLEEQHKIFErfyrvdKSRSKESG-GT 425
Cdd:cd16957 5 ALQVLVENAIRHAFPKRKENNEVRVVVKKD--------QHKVHVSVSDNGQGIPEERLDLLGK------TTVTSEKGtGT 70
|
90 100 110
....*....|....*....|....*....|....*.
gi 1823255651 426 GLGLAIAKHAAVF-HNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16957 71 ALENLNRRLIGLFgSEACLHIESEVHGGTEVWFVIP 106
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-460 |
1.03e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 37.92 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 356 LSNALKYSDPDGEVVVLvgksiappdSEGTPMAYIRVRDNGCGIPLEeqhkiferfyrvdksrsKESGGTGLGLAIAKHA 435
Cdd:cd16917 9 LTNALKHAGASRVRVTL---------SYTADELTLTVVDDGVGFDGP-----------------APPGGGGFGLLGMRER 62
|
90 100
....*....|....*....|....*
gi 1823255651 436 AVFHNGTISVESSVGRGSVFTVRIP 460
Cdd:cd16917 63 AELLGGTLTIGSRPGGGTRVTARLP 87
|
|
| HATPase_RsbT-like |
cd16934 |
Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine ... |
352-459 |
2.68e-03 |
|
Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.
Pssm-ID: 340411 [Multi-domain] Cd Length: 117 Bit Score: 37.73 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 352 VSNLLSNALKYSDpDGEVVVlvgKSIAPPDSEGTPMAyirVRDNGCGIPleeqhkiferfyRVDKSRS---KESGGTGLG 428
Cdd:cd16934 30 VTELARNLLKHAG-GGQVLL---EVVAEGGRVALEIL---AVDQGPGIA------------DVDEALRdgfSTGGGLGLG 90
|
90 100 110
....*....|....*....|....*....|.
gi 1823255651 429 LAIAKHAAvfhnGTISVESSVGRGSVFTVRI 459
Cdd:cd16934 91 LGGVRRLA----DEFDLHSAPGRGTVVVARK 117
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
351-465 |
5.25e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 39.27 E-value: 5.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1823255651 351 LVSNLLSNALKYSDPDGEvvvlVGKSIAPPDSEGTPMAYIRVRDNGCGIPLEEQHkiferfyrvdksRSKESGGTGLGLA 430
Cdd:PRK13560 715 IISELLSNALKHAFPDGA----AGNIKVEIREQGDGMVNLCVADDGIGLPAGFDF------------RAAETLGLQLVCA 778
|
90 100 110
....*....|....*....|....*....|....*
gi 1823255651 431 IAKHAavfhNGTISVESSvgRGSVFTVRIPTEHEG 465
Cdd:PRK13560 779 LVKQL----DGEIALDSR--GGARFNIRFPMSPAG 807
|
|
| |
