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Conserved domains on  [gi|1823463830|ref|WP_166457452|]
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MULTISPECIES: tetratricopeptide repeat protein [unclassified Micromonospora]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 10635815)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
97-123 3.92e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


:

Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.19  E-value: 3.92e-03
                           10        20
                   ....*....|....*....|....*..
gi 1823463830   97 PSLHLNLAECHRKLGELDQARDHLRRA 123
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKA 27
 
Name Accession Description Interval E-value
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
97-123 3.92e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.19  E-value: 3.92e-03
                           10        20
                   ....*....|....*....|....*..
gi 1823463830   97 PSLHLNLAECHRKLGELDQARDHLRRA 123
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKA 27
TPR_1 pfam00515
Tetratricopeptide repeat;
97-123 9.11e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 32.39  E-value: 9.11e-03
                          10        20
                  ....*....|....*....|....*..
gi 1823463830  97 PSLHLNLAECHRKLGELDQARDHLRRA 123
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKA 27
 
Name Accession Description Interval E-value
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
97-123 3.92e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 33.19  E-value: 3.92e-03
                           10        20
                   ....*....|....*....|....*..
gi 1823463830   97 PSLHLNLAECHRKLGELDQARDHLRRA 123
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKA 27
TPR_1 pfam00515
Tetratricopeptide repeat;
97-123 9.11e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 32.39  E-value: 9.11e-03
                          10        20
                  ....*....|....*....|....*..
gi 1823463830  97 PSLHLNLAECHRKLGELDQARDHLRRA 123
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKA 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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