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Conserved domains on  [gi|1827661092|ref|WP_167388816|]
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DUF2726 domain-containing protein [Aeromonas lusitana]

Protein Classification

DUF2726 domain-containing protein( domain architecture ID 10566842)

DUF2726 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2726 pfam10881
Protein of unknown function (DUF2726); This bacterial family of proteins has no known function.
 35-160 2.62e-56

Protein of unknown function (DUF2726); This bacterial family of proteins has no known function.


:

Pssm-ID: 431528  Cd Length: 126  Bit Score: 177.51  E-value: 2.62e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1827661092  35 QETLFSPAERSFLGVLDLAVGDKARVFAKVRVADVLTPEARMGKSKWQQAFNKISAKHFDYLLCHPADLSFLCAVELDDS 114
Cdd:pfam10881   1 RRPLFSPAERAFFHALKKAVGDRYEIFAKVSLSDILSVTKGPGRSNWQRAFNRISAKRFDFLLCDKADLTPVLAIELDGA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1827661092 115 SHRHQKRKARDLFLKEACDSAGLPLLQIPASSHYQVEELREQLLPL 160
Cdd:pfam10881  81 SHYDAKAQKRDAFKNAACESAGIPLLRLSASKSYDVSELRRQIAAL 126
YrdD super family cl33943
DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination ...
 249-283 3.64e-08

DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination and repair];


The actual alignment was detected with superfamily member COG0551:

Pssm-ID: 440317 [Multi-domain]  Cd Length: 695  Bit Score: 54.49  E-value: 3.64e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1827661092 249 CPRCDAPLVEREAKKGphvgRLFLACSRFPECRYA 283
Cdd:COG0551   631 CPKCGKKLVLRKSKKG----KVFYGCSNYPKCKFT 661
 
Name Accession Description Interval E-value
DUF2726 pfam10881
Protein of unknown function (DUF2726); This bacterial family of proteins has no known function.
 35-160 2.62e-56

Protein of unknown function (DUF2726); This bacterial family of proteins has no known function.


Pssm-ID: 431528  Cd Length: 126  Bit Score: 177.51  E-value: 2.62e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1827661092  35 QETLFSPAERSFLGVLDLAVGDKARVFAKVRVADVLTPEARMGKSKWQQAFNKISAKHFDYLLCHPADLSFLCAVELDDS 114
Cdd:pfam10881   1 RRPLFSPAERAFFHALKKAVGDRYEIFAKVSLSDILSVTKGPGRSNWQRAFNRISAKRFDFLLCDKADLTPVLAIELDGA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1827661092 115 SHRHQKRKARDLFLKEACDSAGLPLLQIPASSHYQVEELREQLLPL 160
Cdd:pfam10881  81 SHYDAKAQKRDAFKNAACESAGIPLLRLSASKSYDVSELRRQIAAL 126
YrdD COG0551
DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination ...
 249-283 3.64e-08

DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination and repair];


Pssm-ID: 440317 [Multi-domain]  Cd Length: 695  Bit Score: 54.49  E-value: 3.64e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1827661092 249 CPRCDAPLVEREAKKGphvgRLFLACSRFPECRYA 283
Cdd:COG0551   631 CPKCGKKLVLRKSKKG----KVFYGCSNYPKCKFT 661
zf-C4_Topoisom pfam01396
Topoisomerase DNA binding C4 zinc finger;
249-286 2.82e-07

Topoisomerase DNA binding C4 zinc finger;


Pssm-ID: 307520 [Multi-domain]  Cd Length: 39  Bit Score: 46.10  E-value: 2.82e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1827661092 249 CPRCDAPLVEREAKKGphvgrLFLACSRFPECRYAAPH 286
Cdd:pfam01396   4 CPKCGGDLVLKRGRFG-----KFVGCSNYPECRFTRPL 36
PRK06599 PRK06599
DNA topoisomerase I; Validated
 242-285 9.99e-04

DNA topoisomerase I; Validated


Pssm-ID: 235840 [Multi-domain]  Cd Length: 675  Bit Score: 40.61  E-value: 9.99e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1827661092 242 APAALPHCPRCDAPLVereAKKGPHvGRlFLACSRFPECRYAAP 285
Cdd:PRK06599  633 EIVEEEKCPKCGGPLV---LKKGRY-GK-FLACSGYPECKHIKP 671
 
Name Accession Description Interval E-value
DUF2726 pfam10881
Protein of unknown function (DUF2726); This bacterial family of proteins has no known function.
 35-160 2.62e-56

Protein of unknown function (DUF2726); This bacterial family of proteins has no known function.


Pssm-ID: 431528  Cd Length: 126  Bit Score: 177.51  E-value: 2.62e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1827661092  35 QETLFSPAERSFLGVLDLAVGDKARVFAKVRVADVLTPEARMGKSKWQQAFNKISAKHFDYLLCHPADLSFLCAVELDDS 114
Cdd:pfam10881   1 RRPLFSPAERAFFHALKKAVGDRYEIFAKVSLSDILSVTKGPGRSNWQRAFNRISAKRFDFLLCDKADLTPVLAIELDGA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1827661092 115 SHRHQKRKARDLFLKEACDSAGLPLLQIPASSHYQVEELREQLLPL 160
Cdd:pfam10881  81 SHYDAKAQKRDAFKNAACESAGIPLLRLSASKSYDVSELRRQIAAL 126
YrdD COG0551
DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination ...
 249-283 3.64e-08

DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination and repair];


Pssm-ID: 440317 [Multi-domain]  Cd Length: 695  Bit Score: 54.49  E-value: 3.64e-08
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1827661092 249 CPRCDAPLVEREAKKGphvgRLFLACSRFPECRYA 283
Cdd:COG0551   631 CPKCGKKLVLRKSKKG----KVFYGCSNYPKCKFT 661
YrdD COG0551
DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination ...
 249-285 1.07e-07

DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination and repair];


Pssm-ID: 440317 [Multi-domain]  Cd Length: 695  Bit Score: 52.94  E-value: 1.07e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1827661092 249 CPRCDAPLVEREAKKGPhvgrlFLACSRFPECRYAAP 285
Cdd:COG0551   589 CPKCGKPLVIKKGRYGK-----FLGCSNYPECKYTKP 620
zf-C4_Topoisom pfam01396
Topoisomerase DNA binding C4 zinc finger;
249-286 2.82e-07

Topoisomerase DNA binding C4 zinc finger;


Pssm-ID: 307520 [Multi-domain]  Cd Length: 39  Bit Score: 46.10  E-value: 2.82e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1827661092 249 CPRCDAPLVEREAKKGphvgrLFLACSRFPECRYAAPH 286
Cdd:pfam01396   4 CPKCGGDLVLKRGRFG-----KFVGCSNYPECRFTRPL 36
PRK06599 PRK06599
DNA topoisomerase I; Validated
 242-285 9.99e-04

DNA topoisomerase I; Validated


Pssm-ID: 235840 [Multi-domain]  Cd Length: 675  Bit Score: 40.61  E-value: 9.99e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1827661092 242 APAALPHCPRCDAPLVereAKKGPHvGRlFLACSRFPECRYAAP 285
Cdd:PRK06599  633 EIVEEEKCPKCGGPLV---LKKGRY-GK-FLACSGYPECKHIKP 671
PRK06599 PRK06599
DNA topoisomerase I; Validated
 249-282 6.50e-03

DNA topoisomerase I; Validated


Pssm-ID: 235840 [Multi-domain]  Cd Length: 675  Bit Score: 37.92  E-value: 6.50e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1827661092 249 CPRC-DAPLVEREAKKGPhvgrlFLACSRFPECRY 282
Cdd:PRK06599  588 CPKCgGGPLVLKLGKNGK-----FLGCSGYPECKY 617
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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