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Conserved domains on  [gi|1830370012|ref|WP_168184335|]
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RNA polymerase sigma factor [Muribaculum gordoncarteri]

Protein Classification

RNA polymerase sigma factor( domain architecture ID 11446377)

RNA polymerase sigma factor plays a role in bacterial signal transduction and is regulated by anti-sigma factors. May belong to the ECF-type subfamily. Generally, sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

CATH:  1.10.1740.10
Gene Ontology:  GO:0016987|GO:0006352|GO:0003677
PubMed:  28575802
SCOP:  4003741

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
5-155 3.56e-34

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


:

Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 118.17  E-value: 3.56e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLD-IALENDEAD 83
Cdd:COG1595    26 YRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRELLDeLAEELPDEA 105
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1830370012  84 DDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:COG1595   106 ADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLREALEE 177
 
Name Accession Description Interval E-value
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
5-155 3.56e-34

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 118.17  E-value: 3.56e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLD-IALENDEAD 83
Cdd:COG1595    26 YRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRELLDeLAEELPDEA 105
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1830370012  84 DDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:COG1595   106 ADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLREALEE 177
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
1-153 8.59e-29

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 103.58  E-value: 8.59e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   1 MILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALEND 80
Cdd:TIGR02937   6 LYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFKAWLFRIARNLILDYLRRKRRLRRELDLLEELL 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  81 EADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELY 153
Cdd:TIGR02937  86 DSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
2-155 2.15e-24

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 92.73  E-value: 2.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   2 ILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIAL---E 78
Cdd:PRK11924   19 FRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKGSARTWLLTIARNVCYDLLRRRRREKAVLSDDAlepE 98
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1830370012  79 NDEADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:PRK11924   99 FAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLRECLEA 175
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
96-149 1.09e-09

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 51.30  E-value: 1.09e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1830370012  96 LEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQL 149
Cdd:pfam08281   1 LEALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
96-150 4.07e-09

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 49.80  E-value: 4.07e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1830370012  96 LEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
5-155 3.56e-34

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 118.17  E-value: 3.56e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLD-IALENDEAD 83
Cdd:COG1595    26 YRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRELLDeLAEELPDEA 105
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1830370012  84 DDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:COG1595   106 ADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLREALEE 177
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
1-153 8.59e-29

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 103.58  E-value: 8.59e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   1 MILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALEND 80
Cdd:TIGR02937   6 LYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFKAWLFRIARNLILDYLRRKRRLRRELDLLEELL 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  81 EADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELY 153
Cdd:TIGR02937  86 DSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
2-155 2.15e-24

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 92.73  E-value: 2.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   2 ILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIAL---E 78
Cdd:PRK11924   19 FRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKGSARTWLLTIARNVCYDLLRRRRREKAVLSDDAlepE 98
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1830370012  79 NDEADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:PRK11924   99 FAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLRECLEA 175
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
5-151 1.09e-19

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 80.30  E-value: 1.09e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEA-- 82
Cdd:TIGR02985  10 YYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETLEISESIKAYLFTIVKNRCLNYLRHKQVEEKYQEELAEIEERel 89
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  83 -DDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:TIGR02985  90 sEADPEEELEAKELEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITKALKFLRK 159
SigE-fam_strep TIGR02983
RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors ...
5-152 4.78e-19

RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.


Pssm-ID: 132028 [Multi-domain]  Cd Length: 162  Bit Score: 78.59  E-value: 4.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQcidmTRTRYRRNEPLDIALEN--DEA 82
Cdd:TIGR02983  15 RYPRLLRTAYLLTGDPHEAEDLVQEALVRTYVRWDRIRDPDAPDAYVRRVLVNL----ARSRWRRRRLLELPTRElpDAA 90
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  83 DDDLVKRIDQRDTLekvTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:TIGR02983  91 APDPAPDVALRAAL---ARALRRLPARQRAVVVLRYYEDLSEAQVAEALGISVGTVKSRLSRALARLREL 157
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
5-152 5.12e-15

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 68.53  E-value: 5.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREeleGIQSAKGFCMTTIKR----QCIDmtRTRYRRNEPLDIALEND 80
Cdd:PRK05602   29 KLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAP---SWRPGEARFDTWLHRvvlnLCYD--RLRRRREVPVEDAPDVP 103
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1830370012  81 EADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK05602  104 DPAPGPDAGLEARQRARRVEQALAALPERQREAIVLQYYQGLSNIEAAAVMDISVDALESLLARGRRALRAQ 175
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
5-151 8.60e-13

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 63.44  E-value: 8.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKreeLEGIQSAKGFcMTTIKRQCIDMTRTRYRRNEPLDIALENDEA-- 82
Cdd:PRK11922   39 HNRRLYRTARAILRNDAEAEDVVQEAYLRAFRA---LGTFRGDASL-STWLSRIVLNEALGRLRRRRRLVNLAEMVMAst 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  83 ------------DDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:PRK11922  115 iaggertpladpAEDPERAAARREIRALLERAIDALPDAFRAVFVLRVVEELSVEETAQALGLPEETVKTRLHRARRLLR 194

                  .
gi 1830370012 151 E 151
Cdd:PRK11922  195 E 195
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
4-151 1.15e-12

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 63.79  E-value: 1.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   4 PHYEEMYRVAYIILEDRHDAFDAVQEAVVKLwtKREELEGIQSAKGFCMTTIKRQCIDMTRT-RYRRN------------ 70
Cdd:PRK09636   12 PLRPHLLSVAYRMLGSVADAEDIVQEAWLRW--NNADRAQIRDPRAWLTRVVTRLCLDRLRSaRHRREtyvgpwlpepvv 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  71 EPLDIALENDEADDDLvkridqRDTLEKVtqlMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:PRK09636   90 EELDDPLEAVVAAEDL------SLALMLA---LERLSPLERAAFLLHDVFGVPFDEIASTLGRSPAACRQLASRARKHVR 160

                  .
gi 1830370012 151 E 151
Cdd:PRK09636  161 A 161
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
5-152 1.68e-11

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 59.87  E-value: 1.68e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELE-GIQSAKGFCMTTIKRQCIDMTRTRyrRNEPLDIALENDEAD 83
Cdd:PRK12538   72 HIDRAYAIALRIVGNRADAEDVVQDTMLKVWTHRGRWQhGRAKFSTWLYRVVSNRCIDLRRKP--RTENVDAVPEVADGK 149
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1830370012  84 DDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK12538  150 PDAVSVIERNELSDLLEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMDTTVAAVESLLKRGRQQLRDL 218
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
5-156 2.92e-11

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 58.57  E-value: 2.92e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCID-MTRTRYRRNEPLDialENDEAD 83
Cdd:PRK09643   36 HHRRLWAVARRTSGTREDAADALQDAMLSAHRAAGSFRGDAAVSSWLHRIVVNACLDrLRRAKARPTVPLD---DVYPVA 112
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  84 DDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKHL 156
Cdd:PRK09643  113 QLERDPTARVETALAVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTVKSRCARGRARLAELLGYL 185
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
5-156 5.10e-11

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 57.65  E-value: 5.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWtkREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEADD 84
Cdd:PRK09639   12 YYPDVVQQIFYIVKDRTQAEDLAQEVFLRLY--RSDFKGIENEKGWLIKSARNVAYNYLRSEKRRRARILGEFQWQEVDN 89
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1830370012  85 DLVKRID--QRDTLEKVTQLMDTLPAIQREALRLRaYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKHL 156
Cdd:PRK09639   90 EPSPEEIwiRKEEITKVQEVLAKMTERDRTVLLLR-FSGYSYKEIAEALGIKESSVGTTLARAKKKFRKIYEQM 162
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
8-154 9.18e-11

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 57.06  E-value: 9.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   8 EMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRN-EPLDIALENDEADDDL 86
Cdd:PRK09415   28 EVLQLVYSYVKNKEVAEDLTQEIFVKCYKSLHTYKGKSSLKTWLYRIAINHCKDYLKSWHNKKvIVTEDIFTYMESQKES 107
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  87 VKR--IDQRDTLEKVTQLMDtLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK09415  108 VEEevIQNAEDERLASAVMS-LPIKYREVIYLFYYEELSIKEIAEVTGVNENTVKTRLKKAKELLKKGLE 176
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
7-152 2.93e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 55.83  E-value: 2.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   7 EEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEG--IQSAKGFCMTTIKRQCIDMTRTRYRRNEPLD-IALENDEAD 83
Cdd:PRK12542   20 QKVYYVAYSILNNIQQAEDAVQETFITLYKNLEKLHSlnTQELKRYILRVAKNKAIDSYRKNKRHETFLEeYERESIEAV 99
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  84 DDLVKRIDQRDTLE-KVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK12542  100 DENIEEWEKRKMSEvQIDTLLKELNESNRQVFKYKVFYNLTYQEISSVMGITEANVRKQFERARKRVQNM 169
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
21-153 3.82e-10

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 56.87  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  21 HDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEADDDLVKRID--------- 91
Cdd:PRK08241   44 HDAEDAVQETLLRAWRGYDRFEGRSSLRTWLYRIATNVCLDALEGRARRPLPTDLGAPAADPVDELVERPEvpwlepypd 123
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1830370012  92 ---------------QRDT--LEKVTQLMDtLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELY 153
Cdd:PRK08241  124 alldpaaadpaarvvARESvrLAFVAALQH-LPPRQRAVLILRDVLGWSAAEVAELLDTSVAAVNSALQRARATLAERG 201
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
96-149 1.09e-09

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 51.30  E-value: 1.09e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1830370012  96 LEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQL 149
Cdd:pfam08281   1 LEALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
10-152 1.30e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 54.51  E-value: 1.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  10 YRVAYIILEDRHDAFDAVQEAVVKLW-TKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEADDDLVK 88
Cdd:PRK12524   40 LAVATRVLGDRAEAEDVTQEAMLRLWrIAPDWRQGEARVSTWLYRVVCNLCTDRLRRRRRASVDLDDAPEPADAAPGAEE 119
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1830370012  89 RIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK12524  120 ALIEGDRMRALDAALAALPERQRQAVVLRHIEGLSNPEIAEVMEIGVEAVESLTARGKRALAAL 183
PRK12517 PRK12517
RNA polymerase sigma factor; Provisional
6-152 1.37e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 183569 [Multi-domain]  Cd Length: 188  Bit Score: 53.92  E-value: 1.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   6 YEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQcidmTRTRYRRNEPLDIALENDEADDD 85
Cdd:PRK12517   33 HADIYRYAYWLCKDKHIAEDLVQETFLRAWRSLDSLKDEKAAKAWLITILRRE----NARRFERKQFDLVDIEDDSIEDD 108
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1830370012  86 LVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK12517  109 ASHSSEEEMEQEWLRRQIAKLDPEYREPLLLQVIGGFSGEEIAEILDLNKNTVMTRLFRARNQLKEA 175
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
8-154 2.16e-09

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 53.34  E-value: 2.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   8 EMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEgIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEADDdLV 87
Cdd:PRK09644   13 DVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDYD-NQKVKPWLFKVAYHTFIDFVRKEKKVSFVGTDEIEAIQAES-TE 90
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1830370012  88 KRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK09644   91 EYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLKALLK 157
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
7-156 2.71e-09

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 53.16  E-value: 2.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   7 EEMYRVAYIILEDRHDAFDAVQEAVVKLWTKreeLEGIQSAKGFCmTTIKRQCIDMTRTRYRRNEP---LDIALENDE-- 81
Cdd:PRK09641   29 DKIYQLCYRMLGNRHEAEDAAQEAFIRAYVN---IDSYDINRKFS-TWLYRIATNLTIDRLRKRKPdyyLDAEVAGTEgl 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  82 -------ADDDLVK-RIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELY 153
Cdd:PRK09641  105 tmysqlaADDALPEeQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISEILDLPVGTVKTRIHRGREALRKQL 184

                  ...
gi 1830370012 154 KHL 156
Cdd:PRK09641  185 RHL 187
PRK12516 PRK12516
RNA polymerase sigma factor; Provisional
11-154 3.35e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 183568 [Multi-domain]  Cd Length: 187  Bit Score: 53.05  E-value: 3.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  11 RVAYIILEDRHD-AFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALEndeadDDLVKR 89
Cdd:PRK12516   24 RAFAVSLIGRHDrADDLVQDTIMKAWAKQDHFEVGTNMKAWLFTILRNEFYSQMRKRGREVQDTDGMFT-----EQLAVH 98
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1830370012  90 IDQRDTL--EKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK12516   99 PSQYGTLdlQDFRAALDQLPDDQREAIILVGASGFAYEEAAEICGCAVGTIKSRVNRARQRLQEILQ 165
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
96-150 4.07e-09

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 49.80  E-value: 4.07e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1830370012  96 LEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
10-157 4.93e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 52.76  E-value: 4.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  10 YRVAYIILEDRHDAFDAVQEAVVKLWTKreelEGIQSAKG----FCMTTIKRQCIDMTRTRYRRNEPLD---IALENDEA 82
Cdd:PRK12519   43 YGLALKILGNSQEAEDLTQEIFLSLWRK----SSYDPKRGslssYLLTLTRSRAIDRLRSRRSRQRLLErwqQELLGEAS 118
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1830370012  83 DDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDntrTLLSRARR---QLKELYKHLI 157
Cdd:PRK12519  119 EDTPLEQASLAERSQRVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLG---TVKARARQgllKLRELLQDLL 193
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
16-151 6.68e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 52.13  E-value: 6.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  16 ILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQ-CIDMTRTRYRRNEPLDIALENDEADDDLVKRIDQRD 94
Cdd:PRK12514   39 VLKDRSEAEEALQDVYVKIWTKADRFAVSGLSPMTWLITIARNhAIDRLRARKAVAVDIDEAHDLADPSPGPEAEVIAGD 118
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1830370012  95 TLEKVTQLMDTLPAIQREALRlRAYSD-CSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:PRK12514  119 EGQRIDACLEELEKDRAAAVR-RAYLEgLSYKELAERHDVPLNTMRTWLRRSLLKLRE 175
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
5-136 1.12e-08

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 51.31  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLwTKREELEGIQSAKGFCMTTIKRQCIDMTR-TRYRRNEPLDiALENDE-- 81
Cdd:PRK12527    4 YYRELVRFLSARLGNRQAAEDVAHDAYLRV-LERSSSAQIEHPRAFLYRTALNLVVDRHRrHRVRQAEPLE-VLDEEErl 81
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1830370012  82 ADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTD 136
Cdd:PRK12527   82 HSPSPQTRLDLGQRLALLQRALAELPPACRDSFLLRKLEGLSHQQIAEHLGISRS 136
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
5-151 3.06e-08

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 51.12  E-value: 3.06e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLwtKREELEGIQSAKGFCMTTIKRQCIDMTRT-RYRRNEPLDIALENDEad 83
Cdd:PRK09635   14 HRAYLVDLAFRMVGDIGVAEDMVQEAFSRL--LRAPVGDIDDERGWLIVVTSRLCLDHIKSaSTRRERPQDIAAWHDG-- 89
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1830370012  84 DDLVKRIDQRD--TLEK-----VTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:PRK09635   90 DASVSSVDPADrvTLDDevrlaLLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINE 164
PRK09047 PRK09047
RNA polymerase factor sigma-70; Validated
17-156 3.83e-08

RNA polymerase factor sigma-70; Validated


Pssm-ID: 236367 [Multi-domain]  Cd Length: 161  Bit Score: 49.58  E-value: 3.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  17 LEDRHDAFDAVQEAVVKLWTKReeleGIQSAKGFCMT--TIKRQCI-DMTRTRYRRNEP----LDIALENDEADDDLVKR 89
Cdd:PRK09047    1 VRDDDAALDIVQDAMIKLAEKY----GDRPAAEWPPLfqRILQNRIhDWFRRQKVRNTWvslfSSFSDDDDDDDFDPLET 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  90 ID--------------QRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:PRK09047   77 LDsadegaespadkleRAQVLQLIEEAIQKLPARQREAFLLRYWEDMDVAETAAAMGCSEGSVKTHCSRATHALAKALEA 156

                  .
gi 1830370012 156 L 156
Cdd:PRK09047  157 K 157
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
2-151 5.72e-08

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 49.24  E-value: 5.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   2 ILPHYEEMYRvAYI--ILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRtRYRRneplDIALEN 79
Cdd:TIGR02989   6 LLTRHERALR-AFVrsLVADRDDVDDVLQETFVVAWRKFDQFDPGTNFVAWARGIARNKVLNYRR-KLGR----DRLVFD 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1830370012  80 DEADDDLVKRID------QRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:TIGR02989  80 DDLLEALAAEAEpteaerLSDDRQALEGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYKALQRIRVSLRE 157
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
18-152 1.05e-07

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 48.83  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  18 EDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIAL-ENDEADDDLVKRIDQrdTL 96
Cdd:PRK09637   23 SNEADVDDLLQEVLIKTHSNLHSLKDGSSIKSWLYQIANNTIIDFYRKKNRSEELPDDLLfEDEEREENAKKELAP--CL 100
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1830370012  97 EKvtqLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK09637  101 RP---FIDALPEKYAEALRLTELEGLSQKEIAEKLGLSLSGAKSRVQRGRVKLKEL 153
PRK12511 PRK12511
RNA polymerase sigma factor; Provisional
11-151 1.89e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237123 [Multi-domain]  Cd Length: 182  Bit Score: 48.24  E-value: 1.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  11 RVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDmtRTRYRRNEPLDIALENDEADDDLVKRI 90
Cdd:PRK12511   19 RYARSLTRDSAEAEDLVHDALVRALERRASFRSGGNLRTWLMSILHNAFID--ELRRRRVEARRADELAVLADASLPAAQ 96
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1830370012  91 DQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:PRK12511   97 EHAVRLAQIRDAFFDLPEEQRAALHLVAIEGLSYQEAAAVLGIPIGTLMSRIGRARAALRA 157
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
19-151 3.19e-07

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 47.49  E-value: 3.19e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  19 DRHDAFDAVQEAVVKLWTKREELEGIQSAKGFcMTTIKRQC-IDMTRTRYRRNEPLDIALENDEA--DDDLVKRIDQRDT 95
Cdd:PRK09652   33 DPADAEDLVQETFIKAYRALHSFRGGAAFYTW-LYRIARNTaINYLRKQGRRPPASDVDAEEAEDfdLADALRDISTPEN 111
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  96 L-------EKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:PRK09652  112 EllsaeleQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIGTVRSRIFRAREALRA 174
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
5-154 5.04e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 47.03  E-value: 5.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGiQSAKGFCMTTIKRqCIDMTRTRYRRNEPLD---IALENDE 81
Cdd:PRK12515   31 HHVRVYRFGLRLVRDEQTAEDLVSEVFLDVWRQAGQFEG-RSQVSTWLLSIAR-FKALSALRRRKHEEIDdeaAAAIEDG 108
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  82 ADDDLVKrIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK12515  109 ADTPEVA-LQKSDTSAALRACLAKLSPAHREIIDLVYYHEKSVEEVGEIVGIPESTVKTRMFYARKKLAELLK 180
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
12-151 5.97e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 46.69  E-value: 5.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  12 VAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQ-SAKGFCMTTIKRQCIDMTRTRYRrneplDIALENDEADD--DLVK 88
Cdd:PRK12537   39 VARRIVRDRALAEDIVHDAFIKIWTGAASFDPARgSARGWIYSVTRHLALNVLRDTRR-----EVVLDDDAEETaqTLHE 113
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1830370012  89 RIDQRDTLEKVTQLMDTLPAIQ--REALRLRAYSD-CSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:PRK12537  114 IIDDFDLWANSGKIHRCLEQLEpaRRNCILHAYVDgCSHAEIAQRLGAPLGTVKAWIKRSLKALRE 179
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
11-154 6.53e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 46.41  E-value: 6.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  11 RVAYIILEDRHD-AFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLD-IALENDEADDDLVK 88
Cdd:PRK12547   20 RAFAVSLSSKHDkAEDLVQDTLMKAWAKQDSFEMGTNLKAWLFTILRNEFYSQMRKRGREVQDSDgVFTARVAVHPAQYG 99
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1830370012  89 RIDqrdtLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK12547  100 SLD----LQDFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELLK 161
PRK12544 PRK12544
RNA polymerase factor sigma-70;
7-151 1.11e-06

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 46.33  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   7 EEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIaLENDEADDDL 86
Cdd:PRK12544   29 KQMIKFATLQLSDLHLAEDAVQEALIGALKNADSFAGRAAFKTWVFAILKNKIIDLLRQKKRHVSASSL-LRDEEEEEDF 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  87 VKRID-----QRDTLEKVTQL-----------------MDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSR 144
Cdd:PRK12544  108 EELFDesghwQKDERPQAWGNpeesleqeqfwrifeacLDGLPAKYARVFMMREFIELETNEICHAVDLSVSNLNVLLYR 187

                  ....*..
gi 1830370012 145 ARRQLKE 151
Cdd:PRK12544  188 ARLRLRE 194
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
1-154 2.68e-06

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 44.93  E-value: 2.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   1 MILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRT-RYRRNEPLDIALEN 79
Cdd:PRK09640   31 LMRRYQRTLFNVCARYLGNDRDADDVCQEVMLKVLYGLKNFEGKSKFKTWLYSITYNECITQYRKeRRKRRLMDALSLDP 110
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1830370012  80 -DEADDDLVKRIDQRDTLEKvtqLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK09640  111 lEEASEEKAPKPEERGGLDR---WLVHVNPIDREILVLRFVAELEFQEIADIMHMGLSATKMRYKRALDKLREKFA 183
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
25-156 2.70e-06

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 44.90  E-value: 2.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  25 DAVQEAVVKLWTKREELEGIQ-SAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEADDDLVKRIDQRDTLE--KVTQ 101
Cdd:PRK13919   52 DVVQEVFIRVWKKAKEFDPRRgSARAWLLALAHHAAVDHVRRRAARPQPLEPDEREPEAFDLPGPGLDEEGHLDrtRLGR 131
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1830370012 102 LMDTLPAIQREALRLRAYSDCSVKEISELLGITTDntrTLLSRARRQLKELYKHL 156
Cdd:PRK13919  132 ALKALSPEERRVIEVLYYQGYTHREAAQLLGLPLG---TLKTRARRALSRLKEVL 183
PRK12520 PRK12520
RNA polymerase sigma factor; Provisional
5-151 3.17e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 237126 [Multi-domain]  Cd Length: 191  Bit Score: 44.72  E-value: 3.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRT--RYRRNEPL-DIALENDE 81
Cdd:PRK12520   11 LRPHLLRFARLQLRDPALAEDAVSETLLAVLEHPERFAGQSSLKTYLVGILKHKIIDAIRSgrREVRLSLDdADEQSDDD 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  82 ADDDLVKR-----------------IDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSR 144
Cdd:PRK12520   91 LFDALFAAdghyreppsdwgdpdaaLSRREFFEVLQACVDRLPPRTGRVFMMREWLELETEEICQELQITATNAWVLLYR 170

                  ....*..
gi 1830370012 145 ARRQLKE 151
Cdd:PRK12520  171 ARMRLRE 177
PRK12545 PRK12545
RNA polymerase factor sigma-70;
8-150 5.35e-06

RNA polymerase factor sigma-70;


Pssm-ID: 183584 [Multi-domain]  Cd Length: 201  Bit Score: 44.56  E-value: 5.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   8 EMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYR--RNEPLDIALENDEA-DD 84
Cdd:PRK12545   20 DLLRFARLQLRDADAAEDAVQEALAAAWSQAGRFAGQSAHKTWVFGILRNKLIDTLRARQRtvNLSALDAELDGEALlDR 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  85 DLVKR-------------------IDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRA 145
Cdd:PRK12545  100 ELFKDnghwaahakprpwpkpetiLQQQQFWTLFETCLDHLPEQIGRVFMMREFLDFEIDDICTELTLTANHCSVLLYRA 179

                  ....*
gi 1830370012 146 RRQLK 150
Cdd:PRK12545  180 RTRLR 184
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
5-150 7.23e-06

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 43.53  E-value: 7.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   5 HYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGI-QSAKGFCMTTIKRQCIDMTRT-RYRRNEPLDIALENDE- 81
Cdd:PRK09645   18 HAAPLWRYALRLTGDRARAEDVVQETLLRAWQHPEVLADTgRSARAWLFTVARNLVIDERRSaRARPVEGGDDVLGVPEq 97
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  82 -ADDDLVKRIDQRDtlekVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:PRK09645   98 sAPDEVDRALDRLL----VADALAQLSPEHRAVLVRSYYRGWSTAQIAADLGIPEGTVKSRLHYALRALR 163
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
102-151 8.07e-06

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 40.87  E-value: 8.07e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1830370012 102 LMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:pfam04545   1 ALASLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK12533 PRK12533
RNA polymerase sigma factor; Provisional
1-152 8.36e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 237129 [Multi-domain]  Cd Length: 216  Bit Score: 43.95  E-value: 8.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   1 MILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGiQSAKGFCMTTIKRQCIdmtrTRYRRNEPLDIALEND 80
Cdd:PRK12533   23 LVLPHLDAAYNLARWLCGNASDADDVVQEACMRALRFFDSFRG-DNARPWLLAIVRHTWY----SEWRRRANAHEVAAPD 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  81 EADDD----------------LVKRIDQRdtleKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSR 144
Cdd:PRK12533   98 TLDDAdslddwqpagedplalLLRAEDVR----LVNAALAKLPVEYREVLVLRELEDMSYREIAAIADVPVGTVMSRLAR 173

                  ....*...
gi 1830370012 145 ARRQLKEL 152
Cdd:PRK12533  174 ARRRLAAL 181
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
1-69 1.22e-05

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 41.03  E-value: 1.22e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1830370012   1 MILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQ--SAKGFCMTTIKRQCIDMTRTRYRR 69
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERgvSFSTWLYTIIRNAIIDYLRKQRRT 71
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
6-151 1.45e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 42.80  E-value: 1.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   6 YEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRnepLDIaLENDEADDD 85
Cdd:PRK12543   17 IQEVYKTVHFLVEDKQDVDDVVNEIYIQLWESLRKYDSNRPFRFWLIGLVIKQIHSWRRKRWRR---FRI-FEKAEEQRK 92
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1830370012  86 LVKRIDQRDTLEKVT-----QLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKE 151
Cdd:PRK12543   93 PVSIDFSEDVLSKESnqeliELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVKSRIHAALKKLRQ 163
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
1-151 3.01e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 42.16  E-value: 3.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   1 MILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFcMTTIkrqCIDMTRTRYRRNEP-LDIALE- 78
Cdd:PRK12522    8 LIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKW-ITTI---CVRTFYDFYRKKKRwKDRILDl 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  79 ---------NDEADDDLVKRIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQL 149
Cdd:PRK12522   84 fhkedggeiEFADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKQM 163

                  ..
gi 1830370012 150 KE 151
Cdd:PRK12522  164 RE 165
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
23-150 6.49e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 41.07  E-value: 6.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  23 AFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQ-CIDMTRTRYRRNEPL--DIALENDEADDDLVKRID-QRDTL-E 97
Cdd:PRK12531   54 AMEMVQETMSTVWQKAHLFDGQKSALSTWIYTIIRNlCFDLLRKQKGKDLHIhaDDIWPSDYYPPDLVDHYSpEQDMLkE 133
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  98 KVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:PRK12531  134 QVMKFLDRLPKAQRDVLQAVYLEELPHQQVAEMFDIPLGTVKSRLRLAVEKLR 186
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
8-150 7.92e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 40.90  E-value: 7.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   8 EMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDEA---DD 84
Cdd:PRK12530   19 QMLKFATLQLKDADLAEDVVQEALVSAYKNADSFKGQSALKTWIFAILKNKIIDLIRYRKRFVNESELIEEDSPNsffDE 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  85 DLVKRID--QRDTLEKVTQL-------------MDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQL 149
Cdd:PRK12530   99 KGHWKPEyyEPSEWQEVENTvykeefwlifeacLNHLPAQQARVFMMREYLELSSEQICQECDISTSNLHVLLYRARLQL 178

                  .
gi 1830370012 150 K 150
Cdd:PRK12530  179 Q 179
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
19-152 8.72e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 40.83  E-value: 8.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  19 DRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTR-TRYRRNEPLDIALE------NDEADDDLVKRID 91
Cdd:PRK12513   49 DRALAEDIFQETWLRVIRARAQYQPRARFRTWLYQIARNLLIDHWRrHGARQAPSLDADEQlhaladDGAAPEQQLSLFR 128
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1830370012  92 QRDTLEKVtqlMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK12513  129 DRRRLQAA---LETLPDEQREVFLLREHGDLELEEIAELTGVPEETVKSRLRYALQKLREL 186
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
8-151 1.23e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 40.30  E-value: 1.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   8 EMYRVAYIILEDRHD-AFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALEN--DEADD 84
Cdd:PRK12532   17 LLLHFARLQLPDHPDlAEDLVQETLLSAYSAGDSFQGRALVNSWLFAILKNKIIDALRQIGRQRKVFTLLDDEllDEAFE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  85 DLVKR-------------IDQRDTLE-----KVTQL-MDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRA 145
Cdd:PRK12532   97 SHFSQnghwtpegqpqhwNTPEKSLNnnefqKILQScLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRA 176

                  ....*.
gi 1830370012 146 RRQLKE 151
Cdd:PRK12532  177 RESLRQ 182
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
2-152 1.83e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 39.82  E-value: 1.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   2 ILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNEPLDIALENDE 81
Cdd:PRK12546   13 LVEHLPALRAFAISLTRNVAVADDLVQDTIVKAWTNFDKFQEGTNLRAWLFTILRNTFYSDRRKHKREVPDPEGVHAASL 92
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1830370012  82 AdddlVKRI-DQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKEL 152
Cdd:PRK12546   93 A----VKPAhDGRLAMSDFRAAFAQLPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRARARLAEL 160
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
73-156 4.33e-04

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 39.04  E-value: 4.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  73 LDIALENDEADDDLVK------RIDQRDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTdntrtllSRAR 146
Cdd:COG1191   148 LDEPLEDGDDLLDLLEsgdpeeELEHEELREALAEAIEQLPERERLVLSLYYFEELTLKEIAEVLGVSE-------SRVS 220
                          90
                  ....*....|
gi 1830370012 147 RQLKELYKHL 156
Cdd:COG1191   221 RLHKKALARL 230
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
16-152 1.32e-03

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 37.34  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  16 ILEDRHDAFDAVQEAVVKLWTKREELEGIQ-SAKGFCMTTIKRQCIDMTR------TRYRRNEPLDIALENDEADDDLVK 88
Cdd:PRK09646   50 VLRDPGYSEETTQEVYLEVWRTASRFDPARgSALAWLLTLAHRRAVDRVRseqaasQREVRYGARNVDPAFDQVAEEVEA 129
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1830370012  89 RIDQrdtlEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGIttdNTRTLLSRARRQLKEL 152
Cdd:PRK09646  130 RLER----ERVRDCLDALTDTQRESVTLAYYGGLTYREVAERLAV---PLGTVKTRMRDGLIRL 186
PRK06704 PRK06704
RNA polymerase subunit sigma-70;
2-150 4.05e-03

RNA polymerase subunit sigma-70;


Pssm-ID: 180663 [Multi-domain]  Cd Length: 228  Bit Score: 36.16  E-value: 4.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012   2 ILPHYEEMYRVAYIILEDRHDAFDAVQEAVVKLWTKREElegiqsaKGFCMTTI----KRQCIDMTRTRyRRNEPLDIAL 77
Cdd:PRK06704   23 LIEQYGELKRYCTFLTKNKWDGEDLAQETVCKVLQKYSN-------KDICMTLVykiaRNRWLDQIKSK-SVHEKIRDQI 94
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1830370012  78 ENDEADDDLVkridqrDTLEKVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLK 150
Cdd:PRK06704   95 TFEEPHEKIA------DLHEMVGKVLSSLNVQQSAILLLKDVFQYSIADIAKVCSVSEGAVKASLFRSRNRLK 161
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
22-154 4.41e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 35.83  E-value: 4.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  22 DAFDAVQEAVVKLWTKREELEGIQSAKGFCMTTIKRQCIDMTRTRYRRNE-PLDIALENDEADDdlvkridQRDTLE--K 98
Cdd:PRK12512   52 QAEDIVQEILLAVHLKRHTWDPGAPFAPWLFAIARNKLIDALRRRGRRVFvDIDDFAETLPAEP-------ATETLPagD 124
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1830370012  99 VTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYK 154
Cdd:PRK12512  125 VGRHLETLPPRQRDVVQSISVEGASIKETAAKLSMSEGAVRVALHRGLAALAAKFR 180
PRK09191 PRK09191
two-component response regulator; Provisional
80-149 5.11e-03

two-component response regulator; Provisional


Pssm-ID: 236402 [Multi-domain]  Cd Length: 261  Bit Score: 35.98  E-value: 5.11e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  80 DEADDDLVKRIDQRdtlekvtqlMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQL 149
Cdd:PRK09191   72 PEPGSPFEARAERR---------LAGLTPLPRQAFLLTALEGFSVEEAAEILGVDPAEAEALLDDARAEI 132
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
17-155 9.93e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 34.69  E-value: 9.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1830370012  17 LEDRHDAFDAVQEAVVKLWTKREELEGiqsaKGFCMTTIKR----QCIDMTRTRYRRNEPLDIALENDEA----DDDLVK 88
Cdd:PRK12518   31 LCGRELLDDLVQEVFLRVWKGLPKLRN----PAYFSTWLYRitwnVATDARRQFAQRPSRIQDDSLNDQPsrpsDTPDLM 106
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1830370012  89 RIDQRDTlekVTQLMDTLPAIQREALRLRAYSDCSVKEISELLGITTDNTRTLLSRARRQLKELYKH 155
Cdd:PRK12518  107 QLHYQDL---VQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPVGTVKSRLFYARRQLRKFLQQ 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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