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Conserved domains on  [gi|1844671921|ref|WP_171493771|]
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stealth conserved region 3 domain-containing protein, partial [Acinetobacter seifertii]

Protein Classification

stealth conserved region 3 domain-containing protein( domain architecture ID 11246925)

stealth conserved region 3 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Stealth_CR3 pfam17102
Stealth protein CR3, conserved region 3; Stealth_CR3 is the third of several highly conserved ...
73-109 3.71e-06

Stealth protein CR3, conserved region 3; Stealth_CR3 is the third of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. The domain is found in tandem with CR1, CR2 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system.


:

Pssm-ID: 465347  Cd Length: 49  Bit Score: 42.12  E-value: 3.71e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1844671921  73 HLPQPFLKSVFEEVWEKEENYLREVSSHRFRRPLDVN 109
Cdd:pfam17102   2 HTPHPLRRSVLEEIEERFPEEFARTASHRFRSPDDLS 38
 
Name Accession Description Interval E-value
Stealth_CR3 pfam17102
Stealth protein CR3, conserved region 3; Stealth_CR3 is the third of several highly conserved ...
73-109 3.71e-06

Stealth protein CR3, conserved region 3; Stealth_CR3 is the third of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. The domain is found in tandem with CR1, CR2 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system.


Pssm-ID: 465347  Cd Length: 49  Bit Score: 42.12  E-value: 3.71e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1844671921  73 HLPQPFLKSVFEEVWEKEENYLREVSSHRFRRPLDVN 109
Cdd:pfam17102   2 HTPHPLRRSVLEEIEERFPEEFARTASHRFRSPDDLS 38
 
Name Accession Description Interval E-value
Stealth_CR3 pfam17102
Stealth protein CR3, conserved region 3; Stealth_CR3 is the third of several highly conserved ...
73-109 3.71e-06

Stealth protein CR3, conserved region 3; Stealth_CR3 is the third of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. The domain is found in tandem with CR1, CR2 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system.


Pssm-ID: 465347  Cd Length: 49  Bit Score: 42.12  E-value: 3.71e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1844671921  73 HLPQPFLKSVFEEVWEKEENYLREVSSHRFRRPLDVN 109
Cdd:pfam17102   2 HTPHPLRRSVLEEIEERFPEEFARTASHRFRSPDDLS 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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