NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1847772001|ref|WP_172633559|]
View 

helix-turn-helix domain-containing protein [Coriobacterium glomerans]

Protein Classification

HTH_ARAC and Glyco_hydro_1 domain-containing protein( domain architecture ID 12204110)

HTH_ARAC and Glyco_hydro_1 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
XynB super family cl42385
Beta-xylosidase [Carbohydrate transport and metabolism];
174-602 2.85e-37

Beta-xylosidase [Carbohydrate transport and metabolism];


The actual alignment was detected with superfamily member COG3664:

Pssm-ID: 442881  Cd Length: 490  Bit Score: 145.06  E-value: 2.85e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 174 FKYGRMWGLFgpealCD-------LEKGE--YaNFGTLDEALDAVIEVGLIPWIVIG---KC--SDPERLYECE-N---- 234
Cdd:COG3664    64 FRYIRFHGLF-----HDdmgvyreDADGNpvY-NFTYVDKIFDFLLELGMKPFVELGfmpEAlaSGPQTVFWWKgNvtpp 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 235 ---KAWQHALSSFLSHVLDRYGKQLIVRWRIEmV---------FEGDPSSpQFDIYrdrlAFTRKRIKDIDQAMLIGGAg 302
Cdd:COG3664   138 kdyAKWADLVRAFVRHLIDRYGIDEVRSWYFE-VwnepnlsgfWKGTQEE-YFKLY----DYTARAVKSVDPRLRVGGP- 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 303 fqqlSDEGKLSERIKS-IAYL------LDFVSLKVFPysgsSEVGEQRHPMRIVETgvFIESVQRVRAAMM-HAGVSVPI 374
Cdd:COG3664   211 ----ATAGGAAAWLPDfLEHCakngvpVDFVSTHAYG----TDPGFDGQLSMNPDA--VLRDVEKVRKLIAaSAFPNLPL 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 375 YVTEWSNTISTEDLINDTLFKGCFIIKTCIEAIDSVAGMGYWLASDWYSAEQRSGSLLTGGPGLITKDRIPKPALSAFGF 454
Cdd:COG3664   281 HITEWNTSYTPRDPYHDTAFYAAYIAKSLKRAGDLADSMSYWTFSDIFEEAGPPTQPFHGGFGLLNTNGIKKPVYHAFRM 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 455 LAELTERKLIFKSEDCLICQRE-GDSSILGFNYVQPEKtyylkdessfqpgevlslfKEEKKRCSFLLTHLRNGAYEIRT 533
Cdd:COG3664   361 LNRLGGERLAVGDDDAVATRDDdGRVAVLVWNYHDDDP-------------------AGPARTVELTLTGLPAGKYRLTV 421

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847772001 534 YSCDARYGSIFNQWATLGFAKHLRRSDIEYLKNNSNMHMELEERMITDGVCRIDRLAGANEFFLINLRY 602
Cdd:COG3664   422 YRVDEEHGNAYAAWLEMGSPQQPTREQIAELKAAAELQTSPEVVVVADGKLTLDLTLPRNSVVLIELTP 490
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
8-91 1.22e-24

helix_turn_helix, arabinose operon control protein;


:

Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 97.62  E-value: 1.22e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001    8 RLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTP 87
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 1847772001   88 SEYR 91
Cdd:smart00342  81 SEYR 84
 
Name Accession Description Interval E-value
XynB COG3664
Beta-xylosidase [Carbohydrate transport and metabolism];
174-602 2.85e-37

Beta-xylosidase [Carbohydrate transport and metabolism];


Pssm-ID: 442881  Cd Length: 490  Bit Score: 145.06  E-value: 2.85e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 174 FKYGRMWGLFgpealCD-------LEKGE--YaNFGTLDEALDAVIEVGLIPWIVIG---KC--SDPERLYECE-N---- 234
Cdd:COG3664    64 FRYIRFHGLF-----HDdmgvyreDADGNpvY-NFTYVDKIFDFLLELGMKPFVELGfmpEAlaSGPQTVFWWKgNvtpp 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 235 ---KAWQHALSSFLSHVLDRYGKQLIVRWRIEmV---------FEGDPSSpQFDIYrdrlAFTRKRIKDIDQAMLIGGAg 302
Cdd:COG3664   138 kdyAKWADLVRAFVRHLIDRYGIDEVRSWYFE-VwnepnlsgfWKGTQEE-YFKLY----DYTARAVKSVDPRLRVGGP- 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 303 fqqlSDEGKLSERIKS-IAYL------LDFVSLKVFPysgsSEVGEQRHPMRIVETgvFIESVQRVRAAMM-HAGVSVPI 374
Cdd:COG3664   211 ----ATAGGAAAWLPDfLEHCakngvpVDFVSTHAYG----TDPGFDGQLSMNPDA--VLRDVEKVRKLIAaSAFPNLPL 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 375 YVTEWSNTISTEDLINDTLFKGCFIIKTCIEAIDSVAGMGYWLASDWYSAEQRSGSLLTGGPGLITKDRIPKPALSAFGF 454
Cdd:COG3664   281 HITEWNTSYTPRDPYHDTAFYAAYIAKSLKRAGDLADSMSYWTFSDIFEEAGPPTQPFHGGFGLLNTNGIKKPVYHAFRM 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 455 LAELTERKLIFKSEDCLICQRE-GDSSILGFNYVQPEKtyylkdessfqpgevlslfKEEKKRCSFLLTHLRNGAYEIRT 533
Cdd:COG3664   361 LNRLGGERLAVGDDDAVATRDDdGRVAVLVWNYHDDDP-------------------AGPARTVELTLTGLPAGKYRLTV 421

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847772001 534 YSCDARYGSIFNQWATLGFAKHLRRSDIEYLKNNSNMHMELEERMITDGVCRIDRLAGANEFFLINLRY 602
Cdd:COG3664   422 YRVDEEHGNAYAAWLEMGSPQQPTREQIAELKAAAELQTSPEVVVVADGKLTLDLTLPRNSVVLIELTP 490
Glyco_hydro_39 pfam01229
Glycosyl hydrolases family 39;
130-469 1.41e-27

Glycosyl hydrolases family 39;


Pssm-ID: 426141  Cd Length: 472  Bit Score: 116.17  E-value: 1.41e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 130 RIDMAMTGDPLKPIWTELlnIGSVRELLH--GHIKRQIAFIQGQIAFKYGRMWGLfgpeaLCDL--------EKGEYANF 199
Cdd:pfam01229   4 KVDAARDLRKLTPFWRSC--VGFCPPLPAlqADWDQQLNLAYPHIGFEYVRGHGW-----LLDDitayresvDQGLFYNF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 200 GTLDEALDAVIEVGLIPWIVIGKCS-----------------DPERLYEcenkAWQHALSSFLSHVLDRYGKQLIVRWRI 262
Cdd:pfam01229  77 THIDRILDLLLENGLLPFFELGFMPkrlasgtptvffwegnfTPPKQYE----EWKNLVSLLARHYIGRYGLDEVSKWNF 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 263 EMVFEgdPSSPQFDI-------YRDRLAFTRKRIKDIDQAMLIGGAG--FQQLSDEgkLSERIKSIAYLLDFVSLKVFPY 333
Cdd:pfam01229 153 ETWNE--PNLKDFDWvdmteqeYFNLYKACAEAIKEVSPNLKVGGPAdsFDPWIRS--LLEFCYNGNVPLDFISLHAYSK 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 334 SG---SSEVGEQRHPmriveTGVFIESVQRVRAAMMHAGvSVPIYVTEWSNTISTEDLINDTLFKGCFIIKTCIEAIDSV 410
Cdd:pfam01229 229 KGagsSILILEEEMA-----SEYMLNEVKQVRELIPEFP-DLPVYNTEANPSWSPPQPWHDDPTYAAYVVKVIAQHQDLP 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1847772001 411 AGMGYWLASDWYSAEQRSGSLLTGGPGLITKDRIPKPALSAFGFLAELTERKLIFKSED 469
Cdd:pfam01229 303 DANSYWTFRDVFEENDNAFLSFHGGFGLNNTHPIPKPVLTAFKLLALLDGEQLWAEVSD 361
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
8-91 1.22e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 97.62  E-value: 1.22e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001    8 RLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTP 87
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 1847772001   88 SEYR 91
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
7-93 4.95e-23

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 98.70  E-value: 4.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   7 ERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMT 86
Cdd:COG2207   167 LLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVT 246


                  ....*..
gi 1847772001  87 PSEYRAK 93
Cdd:COG2207   247 PSEYRKR 253
HTH_18 pfam12833
Helix-turn-helix domain;
14-93 5.79e-22

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 89.96  E-value: 5.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001  14 VANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQ-SSMSIARVATECGYTNLSSFNTACNRLLGMTPSEYRA 92
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEdTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 1847772001  93 K 93
Cdd:pfam12833  81 R 81
PRK10371 PRK10371
transcriptional regulator MelR;
3-91 2.58e-11

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 64.84  E-value: 2.58e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   3 AHYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRL 82
Cdd:PRK10371  202 ENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTFGKY 281


                  ....*....
gi 1847772001  83 LGMTPSEYR 91
Cdd:PRK10371  282 VGMSPQQYR 290
 
Name Accession Description Interval E-value
XynB COG3664
Beta-xylosidase [Carbohydrate transport and metabolism];
174-602 2.85e-37

Beta-xylosidase [Carbohydrate transport and metabolism];


Pssm-ID: 442881  Cd Length: 490  Bit Score: 145.06  E-value: 2.85e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 174 FKYGRMWGLFgpealCD-------LEKGE--YaNFGTLDEALDAVIEVGLIPWIVIG---KC--SDPERLYECE-N---- 234
Cdd:COG3664    64 FRYIRFHGLF-----HDdmgvyreDADGNpvY-NFTYVDKIFDFLLELGMKPFVELGfmpEAlaSGPQTVFWWKgNvtpp 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 235 ---KAWQHALSSFLSHVLDRYGKQLIVRWRIEmV---------FEGDPSSpQFDIYrdrlAFTRKRIKDIDQAMLIGGAg 302
Cdd:COG3664   138 kdyAKWADLVRAFVRHLIDRYGIDEVRSWYFE-VwnepnlsgfWKGTQEE-YFKLY----DYTARAVKSVDPRLRVGGP- 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 303 fqqlSDEGKLSERIKS-IAYL------LDFVSLKVFPysgsSEVGEQRHPMRIVETgvFIESVQRVRAAMM-HAGVSVPI 374
Cdd:COG3664   211 ----ATAGGAAAWLPDfLEHCakngvpVDFVSTHAYG----TDPGFDGQLSMNPDA--VLRDVEKVRKLIAaSAFPNLPL 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 375 YVTEWSNTISTEDLINDTLFKGCFIIKTCIEAIDSVAGMGYWLASDWYSAEQRSGSLLTGGPGLITKDRIPKPALSAFGF 454
Cdd:COG3664   281 HITEWNTSYTPRDPYHDTAFYAAYIAKSLKRAGDLADSMSYWTFSDIFEEAGPPTQPFHGGFGLLNTNGIKKPVYHAFRM 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 455 LAELTERKLIFKSEDCLICQRE-GDSSILGFNYVQPEKtyylkdessfqpgevlslfKEEKKRCSFLLTHLRNGAYEIRT 533
Cdd:COG3664   361 LNRLGGERLAVGDDDAVATRDDdGRVAVLVWNYHDDDP-------------------AGPARTVELTLTGLPAGKYRLTV 421

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847772001 534 YSCDARYGSIFNQWATLGFAKHLRRSDIEYLKNNSNMHMELEERMITDGVCRIDRLAGANEFFLINLRY 602
Cdd:COG3664   422 YRVDEEHGNAYAAWLEMGSPQQPTREQIAELKAAAELQTSPEVVVVADGKLTLDLTLPRNSVVLIELTP 490
Glyco_hydro_39 pfam01229
Glycosyl hydrolases family 39;
130-469 1.41e-27

Glycosyl hydrolases family 39;


Pssm-ID: 426141  Cd Length: 472  Bit Score: 116.17  E-value: 1.41e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 130 RIDMAMTGDPLKPIWTELlnIGSVRELLH--GHIKRQIAFIQGQIAFKYGRMWGLfgpeaLCDL--------EKGEYANF 199
Cdd:pfam01229   4 KVDAARDLRKLTPFWRSC--VGFCPPLPAlqADWDQQLNLAYPHIGFEYVRGHGW-----LLDDitayresvDQGLFYNF 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 200 GTLDEALDAVIEVGLIPWIVIGKCS-----------------DPERLYEcenkAWQHALSSFLSHVLDRYGKQLIVRWRI 262
Cdd:pfam01229  77 THIDRILDLLLENGLLPFFELGFMPkrlasgtptvffwegnfTPPKQYE----EWKNLVSLLARHYIGRYGLDEVSKWNF 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 263 EMVFEgdPSSPQFDI-------YRDRLAFTRKRIKDIDQAMLIGGAG--FQQLSDEgkLSERIKSIAYLLDFVSLKVFPY 333
Cdd:pfam01229 153 ETWNE--PNLKDFDWvdmteqeYFNLYKACAEAIKEVSPNLKVGGPAdsFDPWIRS--LLEFCYNGNVPLDFISLHAYSK 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001 334 SG---SSEVGEQRHPmriveTGVFIESVQRVRAAMMHAGvSVPIYVTEWSNTISTEDLINDTLFKGCFIIKTCIEAIDSV 410
Cdd:pfam01229 229 KGagsSILILEEEMA-----SEYMLNEVKQVRELIPEFP-DLPVYNTEANPSWSPPQPWHDDPTYAAYVVKVIAQHQDLP 302

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1847772001 411 AGMGYWLASDWYSAEQRSGSLLTGGPGLITKDRIPKPALSAFGFLAELTERKLIFKSED 469
Cdd:pfam01229 303 DANSYWTFRDVFEENDNAFLSFHGGFGLNNTHPIPKPVLTAFKLLALLDGEQLWAEVSD 361
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
8-91 1.22e-24

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 97.62  E-value: 1.22e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001    8 RLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTP 87
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 1847772001   88 SEYR 91
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
7-93 4.95e-23

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 98.70  E-value: 4.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   7 ERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMT 86
Cdd:COG2207   167 LLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRAFKKRFGVT 246


                  ....*..
gi 1847772001  87 PSEYRAK 93
Cdd:COG2207   247 PSEYRKR 253
HTH_18 pfam12833
Helix-turn-helix domain;
14-93 5.79e-22

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 89.96  E-value: 5.79e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001  14 VANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQ-SSMSIARVATECGYTNLSSFNTACNRLLGMTPSEYRA 92
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLLEdTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80


                  .
gi 1847772001  93 K 93
Cdd:pfam12833  81 R 81
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 1-93 9.69e-20

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 90.22  E-value: 9.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   1 MGAHYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACN 80
Cdd:COG4977   219 MEANLEEPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGSASHFRRAFR 298

                          90
                  ....*....|...
gi 1847772001  81 RLLGMTPSEYRAK 93
Cdd:COG4977   299 RRFGVSPSAYRRR 311
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 3-100 7.85e-18

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 85.49  E-value: 7.85e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   3 AHYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLtQSSMSIARVATECGYTNLSSFNTACNRL 82
Cdd:COG2169    95 AGAEDRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLL-QTGLSVTDAAYAAGFGSLSRFYEAFKKL 173

                          90
                  ....*....|....*...
gi 1847772001  83 LGMTPSEYRAKTSITAIA 100
Cdd:COG2169   174 LGMTPSAYRRGGAGAAIR 191
PRK10371 PRK10371
transcriptional regulator MelR;
3-91 2.58e-11

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 64.84  E-value: 2.58e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   3 AHYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRL 82
Cdd:PRK10371  202 ENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTFGKY 281


                  ....*....
gi 1847772001  83 LGMTPSEYR 91
Cdd:PRK10371  282 VGMSPQQYR 290
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
1-95 1.05e-07

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 53.82  E-value: 1.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   1 MGAHYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACN 80
Cdd:PRK10572  192 ISDHLASEFDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFK 271

                          90
                  ....*....|....*
gi 1847772001  81 RLLGMTPSEYRAKTS 95
Cdd:PRK10572  272 KCTGASPSEFRARCE 286
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 10-95 1.52e-07

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 53.01  E-value: 1.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001  10 TLNLVANRFYLDPAYLSRLIRREtGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTPSE 89
Cdd:PRK09978  160 TLARIASELLMSPSLLKKKLREE-ETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTE 238


                  ....*.
gi 1847772001  90 YRAKTS 95
Cdd:PRK09978  239 YQERSA 244
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
25-91 4.91e-07

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 52.03  E-value: 4.91e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1847772001  25 LSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTPSEYR 91
Cdd:PRK13500  239 LRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWR 305
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
25-91 1.17e-06

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 50.44  E-value: 1.17e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1847772001  25 LSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTPSEYR 91
Cdd:PRK13502  209 LRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCGFEDSNYFSVVFTRETGMTPSQWR 275
ftrA PRK09393
transcriptional activator FtrA; Provisional
 1-93 1.76e-06

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 50.35  E-value: 1.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   1 MGAHYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACN 80
Cdd:PRK09393  227 MRAHLAEPHTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEESLRHHFR 306

                          90
                  ....*....|...
gi 1847772001  81 RLLGMTPSEYRAK 93
Cdd:PRK09393  307 RRAATSPAAYRKR 319
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
25-93 2.02e-06

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 49.90  E-value: 2.02e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847772001  25 LSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTPSEYRAK 93
Cdd:PRK13501  209 LKQLFRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQR 277
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
4-91 5.72e-06

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 48.52  E-value: 5.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   4 HYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLL 83
Cdd:PRK13503  183 HFAEEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGDSNHFSTLFRREF 262


                  ....*...
gi 1847772001  84 GMTPSEYR 91
Cdd:PRK13503  263 SWSPRDIR 270
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 54-91 2.93e-04

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 38.67  E-value: 2.93e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1847772001  54 TQSSMSIARVATECGYtNLSSFNTACNRLLGMTPSEYR 91
Cdd:pfam00165   5 LSTNLTIADIADELGF-SRSYFSRLFKKYTGVTPSQYR 41
PRK15435 PRK15435
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;
9-111 4.69e-04

bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;


Pssm-ID: 185333 [Multi-domain]  Cd Length: 353  Bit Score: 42.86  E-value: 4.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   9 LTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSsMSIARVATECGYTNLSSFNTACNRLLGMTPS 88
Cdd:PRK15435  100 VTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLREALAKG-ESVTTSILNAGFPDSSSYYRKADETLGMTAK 178

                          90       100       110
                  ....*....|....*....|....*....|
gi 1847772001  89 EYR---AKTSITAIAKDVSAGE----ESHR 111
Cdd:PRK15435  179 QFRhggENLAVRYALADCELGRclvaESER 208
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 8-92 1.00e-03

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 41.59  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   8 RLTLNLVANRFYLDPAYLSRLIRRETgINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLLGMTP 87
Cdd:PRK15186  197 KWALKDISDSLYMSCSTLKRKLKQEN-TSFSEVYLNARMNKATKLLRNSEYNITRVAYMCGYDSASYFTCVFKKHFKTTP 275


                  ....*
gi 1847772001  88 SEYRA 92
Cdd:PRK15186  276 SEFLA 280
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
4-91 5.66e-03

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 36.83  E-value: 5.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1847772001   4 HYRERLTLNLVANRFYLDPAYLSRLIRRETGINFKAHLTQMRIECAKRFLTQSSMSIARVATECGYTNLSSFNTACNRLL 83
Cdd:PRK10219   17 HIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQF 96


                  ....*...
gi 1847772001  84 GMTPSEYR 91
Cdd:PRK10219   97 DRTPSDYR 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH