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Conserved domains on  [gi|1847917945|ref|WP_172643395|]
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transposase, partial [Mycobacterium tuberculosis]

Protein Classification

transposase( domain architecture ID 706256)

transposase binds to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0032196|GO:0004803

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Transposase_mut super family cl27632
Transposase, Mutator family;
1-78 1.20e-27

Transposase, Mutator family;


The actual alignment was detected with superfamily member pfam00872:

Pssm-ID: 474953  Cd Length: 380  Bit Score: 102.07  E-value: 1.20e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847917945   1 MTSSH-LIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDTRAATIDVA 78
Cdd:pfam00872   1 MTETHlLLDSEALQAIIELQGKDDLLRTLLKTVMNALLEAELTEHLGAARYERTEERSNQRNGSYSRTFITRAGTLELR 79
 
Name Accession Description Interval E-value
Transposase_mut pfam00872
Transposase, Mutator family;
1-78 1.20e-27

Transposase, Mutator family;


Pssm-ID: 307151  Cd Length: 380  Bit Score: 102.07  E-value: 1.20e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847917945   1 MTSSH-LIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDTRAATIDVA 78
Cdd:pfam00872   1 MTETHlLLDSEALQAIIELQGKDDLLRTLLKTVMNALLEAELTEHLGAARYERTEERSNQRNGSYSRTFITRAGTLELR 79
IS285 COG3328
Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];
10-78 5.45e-16

Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];


Pssm-ID: 442557  Cd Length: 400  Bit Score: 70.23  E-value: 5.45e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1847917945  10 EQLLADQLAQAS--PDLLRGLLSTFIAALMGAEADALCGAGYRERSD-ERSNQRNGYRHRDFDTRAATIDVA 78
Cdd:COG3328     9 EELLSELLEGDDlfDDLLRELLKELLEQALEAELDAHLGAEKYERTGgERGNSRNGYRERTVKTRVGELELR 80
transpos_IS256 NF033543
IS256 family transposase; Members of this family belong to the branch of the IS256-like family ...
 1-78 5.78e-16

IS256 family transposase; Members of this family belong to the branch of the IS256-like family of transposases that includes the founding member. It excludes the IS1249 group.


Pssm-ID: 468074 [Multi-domain]  Cd Length: 406  Bit Score: 70.33  E-value: 5.78e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847917945   1 MTSSHLIDTEQLLADQLAQASP-DLLRGLLSTFIAALMGAEADALCGAGYRERSDeRSNQRNGYRHRDFDTRAATIDVA 78
Cdd:NF033543    4 TAVDELLDEALLGLKALEDLTDdELLRELLKALLEQLLEAELTAHLGAEKYERTG-RGNVRNGYYPRTVLTRGGPVELR 81
 
Name Accession Description Interval E-value
Transposase_mut pfam00872
Transposase, Mutator family;
1-78 1.20e-27

Transposase, Mutator family;


Pssm-ID: 307151  Cd Length: 380  Bit Score: 102.07  E-value: 1.20e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847917945   1 MTSSH-LIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDTRAATIDVA 78
Cdd:pfam00872   1 MTETHlLLDSEALQAIIELQGKDDLLRTLLKTVMNALLEAELTEHLGAARYERTEERSNQRNGSYSRTFITRAGTLELR 79
IS285 COG3328
Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];
10-78 5.45e-16

Transposase (or an inactivated derivative) [Mobilome: prophages, transposons];


Pssm-ID: 442557  Cd Length: 400  Bit Score: 70.23  E-value: 5.45e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1847917945  10 EQLLADQLAQAS--PDLLRGLLSTFIAALMGAEADALCGAGYRERSD-ERSNQRNGYRHRDFDTRAATIDVA 78
Cdd:COG3328     9 EELLSELLEGDDlfDDLLRELLKELLEQALEAELDAHLGAEKYERTGgERGNSRNGYRERTVKTRVGELELR 80
transpos_IS256 NF033543
IS256 family transposase; Members of this family belong to the branch of the IS256-like family ...
 1-78 5.78e-16

IS256 family transposase; Members of this family belong to the branch of the IS256-like family of transposases that includes the founding member. It excludes the IS1249 group.


Pssm-ID: 468074 [Multi-domain]  Cd Length: 406  Bit Score: 70.33  E-value: 5.78e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1847917945   1 MTSSHLIDTEQLLADQLAQASP-DLLRGLLSTFIAALMGAEADALCGAGYRERSDeRSNQRNGYRHRDFDTRAATIDVA 78
Cdd:NF033543    4 TAVDELLDEALLGLKALEDLTDdELLRELLKALLEQLLEAELTAHLGAEKYERTG-RGNVRNGYYPRTVLTRGGPVELR 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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