|
Name |
Accession |
Description |
Interval |
E-value |
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
260-578 |
1.90e-87 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 275.52 E-value: 1.90e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 260 LSRVQGPDGSAEYLWESLPLAGEGWTLHLLRKPQVAADGRNAALGAAAVWLSLVFAALFISQRLRLARLRQRSREELKRQ 339
Cdd:COG4191 36 LLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 340 VEERTR---ELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLETVRLLL-DNGRPAEARQALEPLEQMLTRMA 415
Cdd:COG4191 116 ITELERaeeELRELQEQLVQSEKLAALGELAAGIAHEINNPLAAILGNAELLRRRLeDEPDPEELREALERILEGAERAA 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 416 ALTSHLKTFARNSPMGlRERLDLATVVDQALHLLETRIRSEEVEVALYLARPAW-VRGDAIRLEQVLINLLRNALDAMAD 494
Cdd:COG4191 196 EIVRSLRAFSRRDEEE-REPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPpVLGDPGQLEQVLLNLLINAIDAMEE 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 495 KRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVHEVGGQLQAEN-LSGGARL 573
Cdd:COG4191 275 GEGGRITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFTTKPVGKGTGLGLSISYGIVEKHGGRIEVESePGGGTTF 354
|
....*
gi 1852262400 574 SLTLP 578
Cdd:COG4191 355 TITLP 359
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
354-584 |
2.70e-53 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 187.48 E-value: 2.70e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 354 LVQSAKLAALGQMSAAMAHEINQPLTTQRMQLETVRLLLDNGRPAEA---RQALEPLEQMLTRMAALTSHLKTFARnSPM 430
Cdd:COG5000 192 LLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDRedlERALDTIIRQVDRLKRIVDEFLDFAR-LPE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 431 GLRERLDLATVVDQALHLLETRIRSEEVEVALYLARPA-WVRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQ 509
Cdd:COG5000 271 PQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLpEVLADRDQLEQVLINLLKNAIEAIEEG--GEIEVSTRREDG 348
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1852262400 510 RWRLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYGIVHEVGGQLQAEN-LSGGARLSLTLPQDLEPA 584
Cdd:COG5000 349 RVRIEVSDNGPGIPEEVLERIFEPFFTTKP--KGTGLGLAIVKKIVEEHGGTIELESrPGGGTTFTIRLPLAEEAE 422
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
254-578 |
8.47e-49 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 172.40 E-value: 8.47e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 254 FAANSTLSRVQGPDGSAEYLWESLPLAGEGWTLHLLRKPQVAADGRNAALGAAAVWLSLVFAALFISQRLRLARLRQRSR 333
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 334 EELKRQVEERTRELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLEtvrlLLDNGRPAEARQALEPLEQMLTR 413
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLE----LLLEELDEEQREYLETILRSADR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 414 MAALTSHLKTFAR--NSPMGL-RERLDLATVVDQALHLLETRIRSEEVEVALYLA-RPAWVRGDAIRLEQVLINLLRNAL 489
Cdd:COG0642 157 LLRLINDLLDLSRleAGKLELePEPVDLAELLEEVVELFRPLAEEKGIELELDLPdDLPTVRGDPDRLRQVLLNLLSNAI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 490 DAMADKryKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPV--GEGLGLGLAISYGIVHEVGGQLQAEN- 566
Cdd:COG0642 237 KYTPEG--GTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSrrGGGTGLGLAIVKRIVELHGGTIEVESe 314
|
330
....*....|..
gi 1852262400 567 LSGGARLSLTLP 578
Cdd:COG0642 315 PGKGTTFTVTLP 326
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
340-578 |
1.67e-44 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 161.94 E-value: 1.67e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 340 VEERTRELRTAQEgLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLEtvrLLLDNGRPAEARQALEPLEQMLTRMAALTS 419
Cdd:COG3852 113 LRDITERKRLERE-LRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQ---LLERELPDDELREYTQLIIEEADRLNNLVD 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 420 HLKTFARNSPMgLRERLDLATVVDQALHLLETRIRSEeVEVAL-YLARPAWVRGDAIRLEQVLINLLRNALDAMADKryK 498
Cdd:COG3852 189 RLLSFSRPRPP-EREPVNLHEVLERVLELLRAEAPKN-IRIVRdYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEG--G 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 499 RLEIRIEADGQRW----------RLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYGIVHEVGGQLQAENLS 568
Cdd:COG3852 265 TITIRTRVERQVTlgglrprlyvRIEVIDNGPGIPEEILDRIFEPFFTTKE--KGTGLGLAIVQKIVEQHGGTIEVESEP 342
|
250
....*....|.
gi 1852262400 569 G-GARLSLTLP 578
Cdd:COG3852 343 GkGTTFRIYLP 353
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
334-578 |
1.73e-43 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 164.47 E-value: 1.73e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 334 EELKRQVEERTR---ELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLETVRLLLDNGRPAEARQALEPLEQM 410
Cdd:COG4192 401 QELETEIEERKRiekNLRQTQDELIQAAKMAVVGQTMTSLAHELNQPLNAMSMYLFSAKKALEQENYAQLPTSLDKIEGL 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 411 LTRMAALTSHLKTFARNSPMGLRErLDLATVVDQALHLLETRIRSEEVEvaLYLARPAWVRGDAIRLEQVLINLLRNALD 490
Cdd:COG4192 481 IERMDKIIKSLRQFSRKSDTPLQP-VDLRQVIEQAWELVESRAKPQQIT--LHIPDDLMVQGDQVLLEQVLVNLLVNALD 557
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 491 AMADKryKRLEIRIEADGQRWRLSVLDSGGGIAEADlaKVFDPFFTTKPVgeGLGLGLAISYGIVHEVGGQLQ-AENLSG 569
Cdd:COG4192 558 AVATQ--PQISVDLLSNAENLRVAISDNGNGWPLVD--KLFTPFTTTKEV--GLGLGLSICRSIMQQFGGDLYlASTLER 631
|
....*....
gi 1852262400 570 GARLSLTLP 578
Cdd:COG4192 632 GAMVILEFN 640
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
346-578 |
4.16e-42 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 151.60 E-value: 4.16e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 346 ELRTAQEGLVQSAKLaaLGQMSAAMAHEINQPLTTQRMQLEtvrLLLDNGR--PAEARQALEPLEQMLTRMAALTSHLKT 423
Cdd:COG2205 1 ELEEALEELEELERL--KSEFLANVSHELRTPLTSILGAAE---LLLDEEDlsPEERRELLEIIRESAERLLRLIEDLLD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 424 FARNSPMGL---RERLDLATVVDQALHLLETRIRSEEVEVALYL-ARPAWVRGDAIRLEQVLINLLRNALDAMADKryKR 499
Cdd:COG2205 76 LSRLESGKLsleLEPVDLAELLEEAVEELRPLAEEKGIRLELDLpPELPLVYADPELLEQVLANLLDNAIKYSPPG--GT 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 500 LEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVG--EGLGLGLAISYGIVHEVGGQLQAEN-LSGGARLSLT 576
Cdd:COG2205 154 ITISARREGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRgeGGTGLGLAIVKRIVEAHGGTIWVESePGGGTTFTVT 233
|
..
gi 1852262400 577 LP 578
Cdd:COG2205 234 LP 235
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
350-578 |
6.25e-39 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 146.47 E-value: 6.25e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 350 AQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLEtvrlLLDNGRPAEARQA-LEPLEQMLTRMAALTSHLKTFARNS 428
Cdd:COG5807 134 AEDKLLRSEKLSVAGELAAGIAHEIRNPLTSIKGFLQ----LLQESREDSEREEyFNIIISEIDRINTIITELLVLSKPK 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 429 pMGLRERLDLATVVDQALHLLETRIRSEEVEVALYLARPAW-VRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEAD 507
Cdd:COG5807 210 -KFNFKKLNLNDVLEDVIALLSTEAILKNISIKYDLADDEPvINGDKNQLKQVFINLIKNAIEAMETG--GNITIKTYVE 286
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1852262400 508 GQRWRLSVLDSGGGIAEADLAKVFDPFFTTKpvGEGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:COG5807 287 GDFVVISVKDEGIGIPEEVLEKIGEPFFTTK--EEGTGLGLSICKKIIEEHNGTIEVESKPGkGTTFTIYLP 356
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-577 |
5.74e-37 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 132.58 E-value: 5.74e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVH 556
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|..
gi 1852262400 557 EVGGQLQ-AENLSGGARLSLTL 577
Cdd:cd16976 81 EHGGRLSvANEEGAGARFTFDL 102
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
365-578 |
4.22e-36 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 139.30 E-value: 4.22e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 365 QMSAAMAHEINQPLTTQRMQLETvrlLLDNGR--PAEARQALEPLEQMLTRMAALTSHLKTFAR--NSPMGLR-ERLDLA 439
Cdd:COG5002 167 EFVANVSHELRTPLTSIRGYLEL---LLDGAAddPEERREYLEIILEEAERLSRLVNDLLDLSRleSGELKLEkEPVDLA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 440 TVVDQALHLLETRIRSEEVEVALYL-ARPAWVRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDS 518
Cdd:COG5002 244 ELLEEVVEELRPLAEEKGIELELDLpEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEG--GTITVSLREEDDQVRISVRDT 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1852262400 519 GGGIAEADLAKVFDPFFTTKPV----GEGLGLGLAISYGIVHEVGGQLQAEN-LSGGARLSLTLP 578
Cdd:COG5002 322 GIGIPEEDLPRIFERFYRVDKSrsreTGGTGLGLAIVKHIVEAHGGRIWVESePGKGTTFTITLP 386
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
346-578 |
3.73e-32 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 131.24 E-value: 3.73e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 346 ELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRmqlETVRLLLDNGRPAEARQALEPLEQMLTRMAALTSHLKTFA 425
Cdd:PRK11360 373 ERKRLQRRVARQERLAALGELVAGVAHEIRNPLTAIR---GYVQIWRQQTSDPPSQEYLSVVLREVDRLNKVIDQLLEFS 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 426 RNSPMGLrERLDLATVVDQALHLLETRIRSEEVEVALYLAR---PAWVrgDAIRLEQVLINLLRNALDAMADKRYKRLEI 502
Cdd:PRK11360 450 RPRESQW-QPVSLNALVEEVLQLFQTAGVQARVDFETELDNelpPIWA--DPELLKQVLLNILINAVQAISARGKIRIRT 526
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1852262400 503 RIEADGQRWrLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:PRK11360 527 WQYSDGQVA-VSIEDNGCGIDPELLKKIFDPFFTTKA--KGTGLGLALSQRIINAHGGDIEVESEPGvGTTFTLYLP 600
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
346-578 |
1.03e-31 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 128.55 E-value: 1.03e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 346 ELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLEtvrLLLDNGRpAEARQALEPLEQMLTRMAALTSHLKTFA 425
Cdd:COG5809 253 ERKKLEELLRKSEKLSVVGELAAGIAHEIRNPLTSLKGFIQ---LLKDTID-EEQKTYLDIMLSELDRIESIISEFLVLA 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 426 RNSpMGLRERLDLATVVDQALHLLETRIRSEEVEVALYLARP-AWVRGDAIRLEQVLINLLRNALDAMADKRYKRLEIRI 504
Cdd:COG5809 329 KPQ-AIKYEPKDLNTLIEEVIPLLQPQALLKNVQIELELEDDiPDILGDENQLKQVFINLLKNAIEAMPEGGNITIETKA 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1852262400 505 EADGQRwRLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:COG5809 408 EDDDKV-VISVTDEGCGIPEERLKKLGEPFYTTKE--KGTGLGLMVSYKIIEEHGGKITVESEVGkGTTFSITLP 479
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
310-578 |
1.06e-31 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 127.29 E-value: 1.06e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 310 LSLVFAALFIsqrlrlarlrqrsrEELKRQVEERTRelrtaqegLVQSAKLAALGQMSAAMAHEINQPLTTQR--MQlet 387
Cdd:COG5806 170 LAMLIAVYLI--------------ENLIENILLRKE--------LQRAEKLEVVSELAASIAHEVRNPLTVVRgfIQ--- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 388 vrLLLDNGRPAEARQ-----ALEPLEqmltRMAALTSHLKTFARNSPmGLRERLDLATVVDQALHLLETRIRSEEVEVAL 462
Cdd:COG5806 225 --LLQEPELSDEKRKqyiriALEELD----RAEAIITDYLTFAKPQP-EKLEKIDVSEELEHVIDVLSPYANMNNVEIQT 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 463 YLARPAWVRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKpvGE 542
Cdd:COG5806 298 ELEPGLYIEGDRQKLQQCLINIIKNGIEAMPNG--GTLTIDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFSTK--EK 373
|
250 260 270
....*....|....*....|....*....|....*..
gi 1852262400 543 GLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:COG5806 374 GTGLGTMVSYRIIEAMNGTIRVESEVGkGTTFTITLP 410
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
346-578 |
3.22e-31 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 127.16 E-value: 3.22e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 346 ELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTT-----QRMQLEtvrllldngrPAEARQALEPLEQMLTRMAALTSH 420
Cdd:COG5805 270 EKKEAEELMARSEKLSIAGQLAAGIAHEIRNPLTSikgflQLLQPG----------IEDKEEYFDIMLSELDRIESIISE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 421 LKTFARNSPMGlRERLDLATVVDQALHLLETRIRSEEVEVAL-YLARPAWVRGDAIRLEQVLINLLRNALDAMADKryKR 499
Cdd:COG5805 340 FLALAKPQAVN-KEKENINELIQDVVTLLETEAILHNIQIRLeLLDEDPFIYCDENQIKQVFINLIKNAIEAMPNG--GT 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 500 LEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYGIVHEVGGQLQAE-NLSGGARLSLTLP 578
Cdd:COG5805 417 ITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTTKE--KGTGLGLMVSYKIIENHNGTIDIDsKVGKGTTFTITLP 494
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
74-578 |
3.36e-31 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 127.21 E-value: 3.36e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 74 ELIDALRGPVSETVQGALNRKLERINGAANSSTLELLDRTGLAVAASNWRLPSTYVGSNYGFRPYFKQTRSQGTGRFYAV 153
Cdd:COG4251 5 ALLLLLLLLLLLLLLLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 154 GVTSGVPGYFLASAVNDEHGRFLGAMVVKLEFPELEREWRQGSDILLVSDARGITFIANQDGWRYRELQPLSGADRAELA 233
Cdd:COG4251 85 LLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 234 ETRQYDKQPLVPLHHQVLTRFAANSTLSRVQGPDGSAEYLWESLPLAGEGwtlHLLRKPQVAADGRNAALGAAAVWLSLV 313
Cdd:COG4251 165 ALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLE---AELLLSLGGGLGLLLLLLLLLVLLLLL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 314 FAALFISQRLRLARLRQRSREELKRQVEERTRELRTAQEglvqsaklaALGQMSAAMAHEINQPLTTQRMQLETVRLLLD 393
Cdd:COG4251 242 ILLLLLLILVLELLELRLELEELEEELEERTAELERSNE---------ELEQFAYVASHDLREPLRKISGFSQLLEEDYG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 394 NGRPAEARQALEPLEQMLTRMAALTSHLKTFARNSPMGLR-ERLDLATVVDQALHLLETRIRSEEVEVALylARPAWVRG 472
Cdd:COG4251 313 DKLDEEGREYLERIRDAAERMQALIDDLLAYSRVGRQELEfEPVDLNELLEEVLEDLEPRIEERGAEIEV--GPLPTVRG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALDAMADKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFT--TKPVGEGLGLGLAI 550
Cdd:COG4251 391 DPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRlhSRDEYEGTGIGLAI 470
|
490 500
....*....|....*....|....*....
gi 1852262400 551 SYGIVHEVGGQLQAE-NLSGGARLSLTLP 578
Cdd:COG4251 471 VKKIVERHGGRIWVEsEPGEGATFYFTLP 499
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
1.25e-29 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 112.52 E-value: 1.25e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVH 556
Cdd:cd16943 4 LNQVLLNLLVNAAQAMEGR--GRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSLSYRIIQ 81
|
90 100
....*....|....*....|...
gi 1852262400 557 EVGGQLQAENLSG-GARLSLTLP 578
Cdd:cd16943 82 KHGGTIRVASVPGgGTRFTIILP 104
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
472-578 |
7.89e-29 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 110.43 E-value: 7.89e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 472 GDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKP---VGEGLGLGL 548
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEG--GRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKrsrKIGGTGLGL 78
|
90 100 110
....*....|....*....|....*....|.
gi 1852262400 549 AISYGIVHEVGGQLQAEN-LSGGARLSLTLP 578
Cdd:smart00387 79 SIVKKLVELHGGEISVESePGGGTTFTITLP 109
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
336-578 |
6.79e-28 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 118.13 E-value: 6.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 336 LKRQVEERTR---ELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLET----VRLLLD------NGRPAEARQ 402
Cdd:NF038348 297 LEQEKDEQRRlihELEETHVQLLQSEKLASIGQLAAGVAHEINNPIGFVSANLNTlkgwVHSLLDviaaqeAATPAHAAQ 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 403 ALEPLEQM-----------------------LTRMAALTSHLKTFARNSPmGLRERLDLATVVDQALHLLETRIRSEEVE 459
Cdd:NF038348 377 TRAPLAAAgrdadldyvrgdimtlidesidgAMRVRRIVQDLRDFSRPSG-DEWSFADLHAGLESTLNVVHNELKYKADV 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 460 VALYLARPAwVRGDAIRLEQVLINLLRNAldAMADKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKP 539
Cdd:NF038348 456 VREYGDLPL-VECNAAQLNQVFMNLLVNA--AQAIPGRGTITIRTTCDGDHASIAISDTGKGIPPDVMGRIFDPFFTTKP 532
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1852262400 540 VGEGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:NF038348 533 VGQGTGLGLSISHGIVEHHRGRIDVASEPGrGSTFTITLP 572
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
348-580 |
7.05e-28 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 117.85 E-value: 7.05e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 348 RTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLETVRLLLDNGRPAEAR--QALEPLEQMLTRMAALTSHLKTFA 425
Cdd:PRK13557 148 RDAEDALRQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDADRGRmaRSVENIRAAAERAATLTQQLLAFA 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 426 RNSPmgLRER-LDLATVVDQALHLLEtRIRSEEVEVALYLARPAW-VRGDAIRLEQVLINLLRNALDAMADKRykRLEIR 503
Cdd:PRK13557 228 RKQR--LEGRvLNLNGLVSGMGELAE-RTLGDAVTIETDLAPDLWnCRIDPTQAEVALLNVLINARDAMPEGG--RVTIR 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 504 IE---------------ADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVHEVGGQLQAENLS 568
Cdd:PRK13557 303 TRnveiededlamyhglPPGRYVSIAVTDTGSGMPPEILARVMDPFFTTKEEGKGTGLGLSMVYGFAKQSGGAVRIYSEV 382
|
250
....*....|...
gi 1852262400 569 G-GARLSLTLPQD 580
Cdd:PRK13557 383 GeGTTVRLYFPAS 395
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
342-582 |
1.82e-26 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 112.57 E-value: 1.82e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 342 ERTRELRTA-QEGLVQSAKLAALGQMSAAMAHEINQPLTT---------QRMQLETvrllldngrpaEARQALEPLEQML 411
Cdd:PRK10364 215 RRYLRSRQLlQDEMKRKEKLVALGHLAAGVAHEIRNPLSSikglakyfaERAPAGG-----------EAHQLAQVMAKEA 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 412 TRMAALTSHLKTFARNSPMGLRErLDLATVVDQALHLLETRIRSEEVEVALYLAR--PAwVRGDAIRLEQVLINLLRNAL 489
Cdd:PRK10364 284 DRLNRVVSELLELVKPTHLALQA-VDLNDLINHSLQLVSQDANSREIQLRFTANDtlPE-IQADPDRLTQVLLNLYLNAI 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 490 DAMAdkRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKpvGEGLGLGLAISYGIVHEVGGQLQAENLSG 569
Cdd:PRK10364 362 QAIG--QHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTK--AEGTGLGLAVVHNIVEQHGGTIQVASQEG 437
|
250
....*....|....
gi 1852262400 570 -GARLSLTLPQDLE 582
Cdd:PRK10364 438 kGATFTLWLPVNIT 451
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
6.95e-26 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 102.09 E-value: 6.95e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKRYKR--LEIRIEADGQRW-RLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYG 553
Cdd:cd16920 1 IQQVLINLVRNGIEAMSEGGCERreLTIRTSPADDRAvTISVKDTGPGIAEEVAGQLFDPFYTTKS--EGLGMGLSICRS 78
|
90 100
....*....|....*....|....*.
gi 1852262400 554 IVHEVGGQLQAE-NLSGGARLSLTLP 578
Cdd:cd16920 79 IIEAHGGRLSVEsPAGGGATFQFTLP 104
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
348-578 |
2.14e-24 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 106.37 E-value: 2.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 348 RTAQEGLVQ---SAKLAALGQMSAAMAHEINQPLTTQRmqlETVRLLLDNGRPAEARQALEPLEQMLTRMAALTSHLKTF 424
Cdd:COG5808 223 KTLLERVIQeinTQKLELIGTFAASTAHEIRNPLTSIK---GFIQLLQEKYPELEDQKYFDIIQEEIQRINQIVSEFLVL 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 425 ARNSPMGLrERLDLATVVDQALHLLETRIRSEEVEVALY-LARPAWVRGDAIRLEQVLINLLRNALDAMADKryKRLEIR 503
Cdd:COG5808 300 GKPTAKKL-ELDDLNELIEEILSIIDSEANLKNIRVEKQsLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKEG--GKLTIS 376
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1852262400 504 IEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKpvGEGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:COG5808 377 IENDDEKAVIEVIDNGEGIPEDIIDEIFEPFVTTK--EGGTGLGLSVCKRIVEMHGGEIDIESEEGkGTTFTIRLP 450
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
472-578 |
4.90e-24 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 97.05 E-value: 4.90e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 472 GDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGqRWRLSVLDSGGGIAEADLAKVFDPFFTT-KPVGEGLGLGLAI 550
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKA--GEITVTLSEGG-ELTLTVEDNGIGIPPEDLPRIFEPFSTAdKRGGGGTGLGLSI 77
|
90 100
....*....|....*....|....*....
gi 1852262400 551 SYGIVHEVGGQLQAEN-LSGGARLSLTLP 578
Cdd:pfam02518 78 VRKLVELLGGTITVESePGGGTTVTLTLP 106
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
369-578 |
3.56e-22 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 99.92 E-value: 3.56e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 369 AMAHEINQPLTTQRMQLEtvrlLLDNGRPAEARQAL--------EPLEQMLTRMAALTShLKTfaRNSPMGlRERLDLAT 440
Cdd:PRK11100 262 TLTHELKSPLAAIRGAAE----LLQEDPPPEDRARFtgniltqsARLQQLIDRLLELAR-LEQ--RQELEV-LEPVALAA 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 441 VVDQALHLLETRIRSEEVEVALyLARPAWVRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSGG 520
Cdd:PRK11100 334 LLEELVEAREAQAAAKGITLRL-RPDDARVLGDPFLLRQALGNLLDNAIDFSPEG--GTITLSAEVDGEQVALSVEDQGP 410
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1852262400 521 GIAEADLAKVFDPFFTT-KPVGE--GLGLGLAisygIVHEV----GGQLQAENL-SGGARLSLTLP 578
Cdd:PRK11100 411 GIPDYALPRIFERFYSLpRPANGrkSTGLGLA----FVREVarlhGGEVTLRNRpEGGVLATLTLP 472
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
477-578 |
2.98e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 89.36 E-value: 2.98e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKryKRLEIRIEAD---------------GQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVG 541
Cdd:cd16919 1 LELAILNLAVNARDAMPEG--GRLTIETSNQrvdadyalnyrdlipGNYVCLEVSDTGSGMPAEVLRRAFEPFFTTKEVG 78
|
90 100 110
....*....|....*....|....*....|....*...
gi 1852262400 542 EGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:cd16919 79 KGTGLGLSMVYGFVKQSGGHLRIYSEPGvGTTVRIYLP 116
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
368-583 |
2.36e-20 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 95.49 E-value: 2.36e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 368 AAMAHEINQPLTTQRMQLETVRLLLDNGRPAEARQALEPLEQML--TRmaaLTSHLKTFARNSPMGL---RERLDLATVV 442
Cdd:PRK10490 669 AALSHDLRTPLTVLFGQAEILTLDLASEGSPHARQASEIRQQVLntTR---LVNNLLDMARIQSGGFnlrKEWLTLEEVV 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 443 DQALHLLETRIRSEEVEVALylarPA---WVRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSG 519
Cdd:PRK10490 746 GSALQMLEPGLSGHPINLSL----PEpltLIHVDGPLFERVLINLLENAVKYAGAQ--AEIGIDAHVEGERLQLDVWDNG 819
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1852262400 520 GGIAEADLAKVFDPFftTKPVGE----GLGLGLAISYGIVHEVGGQLQAEN-LSGGARLSLTLPQDLEP 583
Cdd:PRK10490 820 PGIPPGQEQLIFDKF--ARGNKEsaipGVGLGLAICRAIVEVHGGTIWAENrPEGGACFRVTLPLETPP 886
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
334-578 |
2.48e-20 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 95.36 E-value: 2.48e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 334 EELKRQVEERTRELRT---------AQEGLVQSAKLAALgqmsAAMAHEINQPLTTQrmqLETVRLLLDNGRPAEARQAL 404
Cdd:PRK11466 410 EQLAAQVKARTAELQElviehrqarAEAEKASQAKSAFL----AAMSHEIRTPLYGI---LGTAQLLADNPALNAQRDDL 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 405 EPL----EQMLTRMAALTSHLKTFARNSPMGLR-ERLDLATVVDQALHLLETRIRSEEVEVALYLAR--PAWVRGDAIRL 477
Cdd:PRK11466 483 RAItdsgESLLTILNDILDYSAIEAGGKNVSVSdEPFEPRPLLESTLQLMSGRVKGRPIRLATDIADdlPTALMGDPRRI 562
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 478 EQVLINLLRNALdAMADKRYKRLeiRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVHE 557
Cdd:PRK11466 563 RQVITNLLSNAL-RFTDEGSIVL--RSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRGGTGLGLTISSRLAQA 639
|
250 260
....*....|....*....|..
gi 1852262400 558 VGGQLQAENLSG-GARLSLTLP 578
Cdd:PRK11466 640 MGGELSATSTPEvGSCFCLRLP 661
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
358-578 |
3.10e-19 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 90.43 E-value: 3.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 358 AKLAALGQMSAAMAHEINQPLTTQRMQLEtvrlLLDNGRPAEaRQALEpleQMLTRMAALTSHLKTFARNSpmglRERLD 437
Cdd:PRK10604 207 ALIASKKQLIDGIAHELRTPLVRLRYRLE----MSDNLSAAE-SQALN---RDIGQLEALIEELLTYARLD----RPQNE 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 438 LATVVDQALHLLETRI---RSEEVEVALYLARPA---WVRGDAIRLEQVLINLLRNALdamadkRY--KRLEIRIEADGQ 509
Cdd:PRK10604 275 LHLSEPDLPAWLSTHLadiQAVTPEKTVRLDTPHqgdYGALDMRLMERVLDNLLNNAL------RYahSRVRVSLLLDGN 348
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1852262400 510 RWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGE----GLGLGLAISYGIVHEVGGQLQAENLS-GGARLSLTLP 578
Cdd:PRK10604 349 QACLIVEDDGPGIPPEERERVFEPFVRLDPSRDratgGCGLGLAIVHSIALAMGGSVNCDESElGGARFSFSWP 422
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
337-582 |
1.54e-18 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 87.98 E-value: 1.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 337 KRQVEERTRELrTAQEGLVQSAKlaalgqmsaAMAHEINQplttqrmQLETVRLLLDNGRPAEARQALEpleQMLTRMAA 416
Cdd:COG3290 173 RTELERLEEEL-EGVKELAEALR---------AQRHDFRN-------HLHTISGLLQLGEYDEALEYID---EISEELQE 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 417 LTSHLKTFARNspmglrerldlaTVVDqALhLLETRIRSEEVEVALYLARPAWVRGDAIR---LEQVLINLLRNALDAMA 493
Cdd:COG3290 233 LIDSLLSRIGN------------PVLA-AL-LLGKAARARERGIDLTIDIDSDLPDLPLSdtdLVTILGNLLDNAIEAVE 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 494 --DKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPvGEGLGLGLAISYGIVHEVGGQLQAENLSG-G 570
Cdd:COG3290 299 klPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFSTKL-GEGRGLGLALVKQIVEKYGGTIEVESEEGeG 377
|
250
....*....|..
gi 1852262400 571 ARLSLTLPQDLE 582
Cdd:COG3290 378 TVFTVRLPKEGE 389
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
338-578 |
5.26e-18 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 87.81 E-value: 5.26e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 338 RQVEERTRELrtaQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLETVRLLLDNGRPAeaRQALEPLEQMLTRMAAL 417
Cdd:PRK13837 428 RRLETERDAL---ERRLEHARRLEAVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRA--ARYIDEIISAGARARLI 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 418 TSHLKTFARNSPmGLRERLDLATVVDQALHLLETRIrSEEVEVAL-YLARPAWVRGDAIRLEQVLINLLRNALDAMAD-- 494
Cdd:PRK13837 503 IDQILAFGRKGE-RNTKPFDLSELVTEIAPLLRVSL-PPGVELDFdQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGag 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 495 -----------KRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGLGLAISYGIVHEVGGQLQ 563
Cdd:PRK13837 581 rvdislsraklRAPKVLSHGVLPPGRYVLLRVSDTGAGIDEAVLPHIFEPFFTTRA--GGTGLGLATVHGIVSAHAGYID 658
|
250
....*....|....*.
gi 1852262400 564 AENLSG-GARLSLTLP 578
Cdd:PRK13837 659 VQSTVGrGTRFDVYLP 674
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
335-583 |
2.65e-17 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 85.85 E-value: 2.65e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 335 ELKRQVEERTRELRTAQeglvQSAKLAALGQMS--AAMAHEINQPLTTQRMQLEtvrlLLDNGR-PAEARQALEPLEQML 411
Cdd:PRK15347 372 TLENKVAERTQALAEAK----QRAEQANKRKSEhlTTISHEIRTPLNGVLGALE----LLQNTPlTAEQMDLADTARQCT 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 412 TRMAALTSHLKTFAR--NSPMGLR-ERLDLATVVDQALHLLETRIRSEEV--------EVALYLARpawvrgDAIRLEQV 480
Cdd:PRK15347 444 LSLLAIINNLLDFSRieSGQMTLSlEETALLPLLDQAMLTIQGPAQSKSLtlrtfvgaHVPLYLHL------DSLRLRQI 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 481 LINLLRNALDAMADKRykrLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVHEVGG 560
Cdd:PRK15347 518 LVNLLGNAVKFTETGG---IRLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADTHSQGTGLGLTIASSLAKMMGG 594
|
250 260
....*....|....*....|....*
gi 1852262400 561 QLQAENLSG-GARLSLTLP-QDLEP 583
Cdd:PRK15347 595 ELTLFSTPGvGSCFSLVLPlNEYAP 619
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
477-578 |
2.05e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 75.22 E-value: 2.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALdamadKRYKRLEIRI-------EADGQRWRLSVLDSGGGIAEADLAKVFDPFF-----TTKPVGeGL 544
Cdd:cd16922 1 LRQILLNLLGNAI-----KFTEEGEVTLrvsleeeEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSqadssTTRKYG-GT 74
|
90 100 110
....*....|....*....|....*....|....*
gi 1852262400 545 GLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:cd16922 75 GLGLAISKKLVELMGGDISVESEPGqGSTFTFTLP 109
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
473-578 |
1.27e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 72.96 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALDAMADKRYKRLEIRIEA-DGQRWRLS--VLDSGGGIAEADLAKVFDPFFTTKPVGegLGLGLA 549
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRPSDVGEVRIRVeADQDGRIVliVCDNGKGFPREMRHRATEPYVTTRPKG--TGLGLA 78
|
90 100 110
....*....|....*....|....*....|
gi 1852262400 550 ISYGIVHEVGGQLQAENL-SGGARLSLTLP 578
Cdd:cd16944 79 IVKKIMEEHGGRISLSNReAGGACIRIILP 108
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
3.53e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 71.59 E-value: 3.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALdamadkRYKR--LEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPV----GEGLGLGLAI 550
Cdd:cd16949 1 LARALENVLRNAL------RYSPskILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSArdreSGGTGLGLAI 74
|
90 100
....*....|....*....|....*....
gi 1852262400 551 SYGIVHEVGGQLQAENLS-GGARLSLTLP 578
Cdd:cd16949 75 AERAIEQHGGKIKASNRKpGGLRVRIWLP 103
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
367-579 |
3.70e-15 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 78.28 E-value: 3.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 367 SAAMAHEINQPLTTQRMQLETVrlLLDNGRPAEARQALEPLEQMLTRMAALTSHLKTFARNSPMGL---RERLDLATVVD 443
Cdd:PRK09835 266 SADIAHEIRTPITNLITQTEIA--LSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLipeKKMLDLADEVG 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 444 QALHLLETRirSEEVEVALYL-ARPAWVRGDAIRLEQVLINLLRNALdamadkRY----KRLEIRIEADGQRWRLSVLDS 518
Cdd:PRK09835 344 KVFDFFEAW--AEERGVELRFvGDPCQVAGDPLMLRRAISNLLSNAL------RYtpagEAITVRCQEVDHQVQLVVENP 415
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1852262400 519 GGGIAEADLAKVFDPFFTTKPV----GEGLGLGLAISYGIVHEVGGQLQAENLSGGARLSLTLPQ 579
Cdd:PRK09835 416 GTPIAPEHLPRLFDRFYRVDPSrqrkGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLPR 480
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
483-578 |
6.07e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 70.78 E-value: 6.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 483 NLLRNALDAMADKRY--KRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEgLGLGLAISYGIVHEVGG 560
Cdd:cd16915 7 NLIDNALDALAATGApnKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGVSTKGQGE-RGIGLALVRQSVERLGG 85
|
90
....*....|....*....
gi 1852262400 561 QLQAEN-LSGGARLSLTLP 578
Cdd:cd16915 86 SITVESePGGGTTFSIRIP 104
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
365-585 |
2.40e-14 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 75.44 E-value: 2.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 365 QMSAA-MA---HEINQPLTTQRMQLETvrlLLDNGRPAEArqalEPLEQMLTRMAALTS-----HLKTFARNSPMGLR-E 434
Cdd:PRK10549 238 QMRRDfMAdisHELRTPLAVLRGELEA---IQDGVRKFTP----ESVASLQAEVGTLTKlvddlHQLSLSDEGALAYRkT 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 435 RLDLATVVDQALHLLETRIRSEEVEVALYLARPAWVRGDAIRLEQVLINLLRNALdamadkRYK----RLEIRIEADGQR 510
Cdd:PRK10549 311 PVDLVPLLEVAGGAFRERFASRGLTLQLSLPDSATVFGDPDRLMQLFNNLLENSL------RYTdsggSLHISAEQRDKT 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 511 WRLSVLDSGGGIAEADLAKVFDPFFTTKP----VGEGLGLGLAISYGIVHEVGGQLQAENLS-GGARLSLTLPQDLEPAC 585
Cdd:PRK10549 385 LRLTFADSAPGVSDEQLQKLFERFYRTEGsrnrASGGSGLGLAICLNIVEAHNGRIIAAHSPfGGVSITVELPLERDLQR 464
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
473-578 |
3.33e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 69.03 E-value: 3.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALdamadkRYK----RLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFF-----TTKPVGeG 543
Cdd:cd16946 1 DRDRLQQLFVNLLENSL------RYTdtggKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYrvessRNRASG-G 73
|
90 100 110
....*....|....*....|....*....|....*.
gi 1852262400 544 LGLGLAISYGIVHEVGGQLQAENLS-GGARLSLTLP 578
Cdd:cd16946 74 SGLGLAICHNIALAHGGTISAEHSPlGGLRLVLTLP 109
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
6.36e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 68.20 E-value: 6.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADK--------RYKRlEIRIEADGQRW--RLSVLDSGGGIAEADLAKVFDPFFTTKPvgEGLGL 546
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSggeiilrtRTQR-QVTLGHPRHRLalRVSVIDNGPGIPPDLQDTIFYPMVSGRE--NGTGL 77
|
90 100 110
....*....|....*....|....*....|..
gi 1852262400 547 GLAISYGIVHEVGGQLQAENLSGGARLSLTLP 578
Cdd:cd16918 78 GLAIAQNIVSQHGGVIECDSQPGHTVFSVSLP 109
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
2.07e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 66.30 E-value: 2.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALdamadkRY--KRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGE----GLGLGLAI 550
Cdd:cd16939 1 MARALDNLLRNAL------RYahRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDratgGFGLGLAI 74
|
90 100
....*....|....*....|....*....
gi 1852262400 551 SYGIVHEVGGQLQAENLS-GGARLSLTLP 578
Cdd:cd16939 75 VHRVALWHGGHVECDDSElGGACFRLTWP 103
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
3.24e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 65.81 E-value: 3.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVG--EGLGLGLAISYGI 554
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSREeyEGTGVGLAIVRKI 80
|
90 100
....*....|....*....|....*
gi 1852262400 555 VHEVGGQLQAEN-LSGGARLSLTLP 578
Cdd:cd16921 81 IERHGGRIWLESePGEGTTFYFTLP 105
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
1.40e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 64.13 E-value: 1.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKRyKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGL----GLGLAISY 552
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDT-GRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFgqhsGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|.
gi 1852262400 553 GIVHEVGGQLQAENLS-----GGARLSLTLP 578
Cdd:cd16953 80 QIIEAHGGISVAENHNqpgqvIGARFTVQLP 110
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-575 |
5.11e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 62.47 E-value: 5.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALdamadkRYKRLEIRI--EADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPV--GEGLGLGLAISY 552
Cdd:cd16950 1 LKRVLSNLVDNAL------RYGGGWVEVssDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNArgTSGTGLGLAIVQ 74
|
90 100
....*....|....*....|....*.
gi 1852262400 553 GIVHEVGGQLQAENLSGG---ARLSL 575
Cdd:cd16950 75 RISDAHGGSLTLANRAGGglcARIEL 100
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
365-582 |
5.30e-12 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 67.69 E-value: 5.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 365 QMSAAMAHEINQPLTTQRMQLEtvrlLLDNGRPAEArqalEPLEQMLTRMAALTSHLKTFAR---NSPMGLRERLDLATV 441
Cdd:PRK10755 139 LFTADVAHELRTPLAGIRLHLE----LLEKQHHIDV----APLIARLDQMMHTVEQLLQLARagqSFSSGHYQTVKLLED 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 442 VDQALH-----LLETR---IRSEEVEVALYlarpawVRGDAIRLEQVLINLLRNAldamadKRYK----RLEIRIEADGQ 509
Cdd:PRK10755 211 VILPSQdelseMLEQRqqtLLLPESAADIT------VQGDATLLRLLLRNLVENA------HRYSpegsTITIKLSQEDG 278
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1852262400 510 RWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGLGLAISYGIVHEVGGQLQAENLS--GGARLSLTLPQDLE 582
Cdd:PRK10755 279 GAVLAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQerSGTRAWVWLPKAQN 353
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
433-578 |
1.27e-11 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 66.86 E-value: 1.27e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 433 RERLDLATVVDQALHLlETRiRSEEVEVALYL-ARPAWVRGDAIRleQVLINLLRNALdamadkRYKRLEIRIEA--DGQ 509
Cdd:PRK09467 291 MEMADLNALLGEVIAA-ESG-YEREIETALQPgPIEVPMNPIAIK--RALANLVVNAA------RYGNGWIKVSSgtEGK 360
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1852262400 510 RWRLSVLDSGGGIAEADLAKVFDPFFT--TKPVGEGLGLGLAISYGIVHEVGGQLQAENLS-GGARLSLTLP 578
Cdd:PRK09467 361 RAWFQVEDDGPGIPPEQLKHLFQPFTRgdSARGSSGTGLGLAIVKRIVDQHNGKVELGNSEeGGLSARAWLP 432
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
473-577 |
6.51e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 59.40 E-value: 6.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALDAMADkrYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEG---LGLGLA 549
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPE--GGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGqksTGLGLA 78
|
90 100
....*....|....*....|....*...
gi 1852262400 550 ISYGIVHEVGGQLQAENLSGGARLSLTL 577
Cdd:cd16945 79 FVQEVAQLHGGRITLRNRPDGVLAFLTL 106
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
464-572 |
3.27e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 57.80 E-value: 3.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 464 LARPAWVRGDAIRLEQVLINLLRNALdamadkRYK----RLEIRIEADGQRwRLSVLDSGGGIAEADLAKVFDPFFTTKP 539
Cdd:cd16940 1 SAADIQVQGDALLLFLLLRNLVDNAV------RYSpqgsRVEIKLSADDGA-VIRVEDNGPGIDEEELEALFERFYRSDG 73
|
90 100 110
....*....|....*....|....*....|....
gi 1852262400 540 V-GEGLGLGLAISYGIVHEVGGQLQAENLSGGAR 572
Cdd:cd16940 74 QnYGGSGLGLSIVKRIVELHGGQIFLGNAQGGGL 107
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
7.71e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 56.53 E-value: 7.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNAldamadKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTK---PVGEGLGLGLAISYG 553
Cdd:cd16948 10 IGQIVSNALKYS------KQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGEngrNFQESTGMGLYLVKK 83
|
90 100
....*....|....*....|....*.
gi 1852262400 554 IVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:cd16948 84 LCDKLGHKIDVESEVGeGTTFTITFP 109
|
|
| dCache_1 |
pfam02743 |
Cache domain; Double cache domain 1 covers the last three strands from the membrane distal ... |
35-215 |
1.19e-09 |
|
Cache domain; Double cache domain 1 covers the last three strands from the membrane distal PAS-like domain, the first two strands of the membrane proximal domain, and the connecting elements between the two domains. This domain when present in chemoreceptors recognize several signals such as proteinogenic amino acids, GABA, Histamine and polyamines, decanoic acid, Autoinducer-2, purine derivatives, quaternary amines, citrate and taurine, among others. When associated with histidine kinases, it recognizes C3/C4-dicarboxylic acids, Spermine, guanosine and Autoinducer-2 (Mantilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1 https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 460673 [Multi-domain] Cd Length: 237 Bit Score: 58.89 E-value: 1.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 35 QAMENDAQRAHQQLG-LYANTLHTLIDRYRALPAVLALDPELIDALrgpvSETVQGALNRKLERINGAANSSTLELLDRT 113
Cdd:pfam02743 1 KAIKEQAEEQLLSLAkQLAENIESYLDSLEEILELLASNPDLQDLL----SAPAEEELAKLESLLRSNPGISSIYLVDAD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 114 GLAVAASNWrlPSTYVGSNYGFRPYFKQTRSQGTGRFY-----AVGVTSGVPGYFLASAVNDEHGRFLGAMVVKLEFPEL 188
Cdd:pfam02743 77 GRVLASSDE--SPSYPGLDVSERPWYKEALKGGGGIIWvfsspYPSSESGEPVLTIARPIYDDDGEVIGVLVADLDLDTL 154
|
170 180
....*....|....*....|....*..
gi 1852262400 189 EREWRQgsdilLVSDARGITFIANQDG 215
Cdd:pfam02743 155 QELLSQ-----IKLGEGGYVFIVDSDG 176
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
467-550 |
3.62e-09 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 59.60 E-value: 3.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 467 PAWVRGDAIRLEQVLINLLRNA----------LDAMADKRYkrLEIRIEadgqrwrlsvlDSGGGIAEADLAKVFDPFFT 536
Cdd:PRK10841 553 PVALNGDPMRLQQVISNLLSNAikftdtgcivLHVRVDGDY--LSFRVR-----------DTGVGIPAKEVVRLFDPFFQ 619
|
90 100
....*....|....*....|.
gi 1852262400 537 tkpVG-------EGLGLGLAI 550
Cdd:PRK10841 620 ---VGtgvqrnfQGTGLGLAI 637
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
372-578 |
5.85e-09 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 58.41 E-value: 5.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 372 HEINQPLTtqRMQLETVRLLLDNGRPAE-ARQALEP--LEQM------LTRMAaLTSHLktfarnspmgLRERLDLAT-- 440
Cdd:PRK09470 252 HELRTPLT--RLQLATALLRRRQGESKElERIETEAqrLDSMindllvLSRNQ-QKNHL----------ERETFKANSlw 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 441 --VVDQALHLLETRIRSEEVEVALylaRPAWVRGDAIRLEQVLINLLRNALdamadkRY--KRLEIRIEADGQRWRLSVL 516
Cdd:PRK09470 319 seVLEDAKFEAEQMGKSLTVSAPP---GPWPINGNPNALASALENIVRNAL------RYshTKIEVAFSVDKDGLTITVD 389
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1852262400 517 DSGGGIAEADLAKVFDPFFTtkpVGE-------GLGLGLAISYGIVHEVGGQLQAENlS--GGARLSLTLP 578
Cdd:PRK09470 390 DDGPGVPEEEREQIFRPFYR---VDEardresgGTGLGLAIVENAIQQHRGWVKAED-SplGGLRLTIWLP 456
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
466-566 |
5.87e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 54.44 E-value: 5.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 466 RPAWVRGDAIRLEQVLINLLRNALDAMADKRYkrLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVG---- 541
Cdd:cd16947 10 RPIYANANTEALQRILKNLISNAIKYGSDGKF--LGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRnsak 87
|
90 100
....*....|....*....|....*
gi 1852262400 542 EGLGLGLAISYGIVHEVGGQLQAEN 566
Cdd:cd16947 88 QGNGLGLTITKRLAESMGGSIYVNS 112
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
360-426 |
7.81e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 52.21 E-value: 7.81e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1852262400 360 LAALGQMSAAMAHEINQPLTTQRMQLETvrLLLDNGRPAEARQALEPLEQMLTRMAALTSHLKTFAR 426
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALEL--LEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PDC1_DGC_like |
cd12914 |
first PDC (PhoQ/DcuS/CitA) domain of diguanylate-cyclase and similar domains; Members of this ... |
59-181 |
9.11e-09 |
|
first PDC (PhoQ/DcuS/CitA) domain of diguanylate-cyclase and similar domains; Members of this subfamily display varying domain architectures but all contain double PDC (PhoQ/DcuS/CitA) sensor domains. This model represents the first PDC domain of Diguanylate-cyclases (DGCs), Histidine kinases (HKs), and other similar domains. Many members of this subfamily contain a C-terminal DGC (also called GGDEF) domain. DGCs regulate the turnover of cyclic diguanosine monophosphate. HK receptors are part of two-component systems (TCS) in bacteria that play a critical role for sensing and adapting to environmental changes. Typically, HK receptors contain an extracellular sensing domain flanked by two transmembrane helices, an intracellular dimerization histidine phosphorylation domain (DHp), and a C-terminal kinase domain, with many variations on this theme. In the case of HKs, signals detected by the sensor domain are transmitted through DHp to the kinase domain, resulting in the phosphorylation of a conserved histidine residue in DHp; phosphotransfer to a conserved aspartate in its cognate response regulator (RR) follows, which leads to the activation of genes for downstream cellular responses.
Pssm-ID: 350339 Cd Length: 123 Bit Score: 53.93 E-value: 9.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 59 IDRYRALPAVLALDPElIDALRGPVSETVQGALNRKLERINGAANsstLELLDRTGLAVAASNwrlPSTYVGSNYGFRPY 138
Cdd:cd12914 1 LDEADLLLRSLADDLE-ARGAASADPAALQALLRRLLARLPEVRS---IFVVDADGRVVASSG---PGPAPGLDVSDRDY 73
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1852262400 139 FKQTRSQGTGRF---YAVGVTSGVPGYFLASAVNDEHGRFLGAMVV 181
Cdd:cd12914 74 FQAARAGGGGLFisePVISRVTGKPVIPLSRPIRDADGRFAGVVVA 119
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
473-575 |
1.05e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 53.23 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALDAMADKRYkrLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPV---GEGLGLGLA 549
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGT--VSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSrrsGGHYGMGLY 78
|
90 100
....*....|....*....|....*..
gi 1852262400 550 ISYGIVHEVGGQLQAEN-LSGGARLSL 575
Cdd:cd16975 79 IAKNLVEKHGGSLIIENsQKGGAEVTV 105
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
427-561 |
3.26e-08 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 56.78 E-value: 3.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 427 NSPMGLRErldlatVVDQALHLLETRIRSEEVEVALYLAR--PAWVRGDAIRLEQVLINLLRNALdamadkryK------ 498
Cdd:PRK11107 363 NIPFSLRE------TLDEVVTLLAHSAHEKGLELTLNIDPdvPDNVIGDPLRLQQIITNLVGNAI--------Kftesgn 428
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1852262400 499 ---RLEIRIEADGQ-RWRLSVLDSGGGIAEADLAKVFDPF-----FTTKPVGeGLGLGLAISYGIVHEVGGQ 561
Cdd:PRK11107 429 idiLVELRALSNTKvQLEVQIRDTGIGISERQQSQLFQAFrqadaSISRRHG-GTGLGLVITQKLVNEMGGD 499
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
371-570 |
5.21e-08 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 55.43 E-value: 5.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 371 AHEINQPLTTQRMQLETVRLLLDNgrPAEARQALEPLEQMLTRMAALTSHLKTFAR----NSPMGLRERlDLATVVDQAL 446
Cdd:PRK10337 245 AHELRSPLAALKVQTEVAQLSDDD--PQARKKALLQLHAGIDRATRLVDQLLTLSRldslDNLQDVAEI-PLEDLLQSAV 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 447 HLLETRIRSEEVEVALYL-ARPAWVRGDAIRLEQVLINLLRNALdamadkRYK----RLEIRIEADgqrwRLSVLDSGGG 521
Cdd:PRK10337 322 MDIYHTAQQAGIDVRLTLnAHPVIRTGQPLLLSLLVRNLLDNAI------RYSpqgsVVDVTLNAR----NFTVRDNGPG 391
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1852262400 522 IAEADLAKVFDPFFttKPVGE---GLGLGLAISYGIVHEVGGQLQAENLSGG 570
Cdd:PRK10337 392 VTPEALARIGERFY--RPPGQeatGSGLGLSIVRRIAKLHGMNVSFGNAPEG 441
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
362-426 |
7.92e-08 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 49.52 E-value: 7.92e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1852262400 362 ALGQMSAAMAHEINQPLTTQRMQLEtvrLLLDNGRPAEARQALEPLEQMLTRMAALTSHLKTFAR 426
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLE---LLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
480-580 |
8.43e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 54.92 E-value: 8.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 480 VLINLLRNALDAMADKRYKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKpvGEGLGLGLAISYGIVHEVG 559
Cdd:PRK11086 437 ILGNLIENALEAVGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKGYSTK--GSNRGVGLYLVKQSVENLG 514
|
90 100
....*....|....*....|..
gi 1852262400 560 GQLQAENLSG-GARLSLTLPQD 580
Cdd:PRK11086 515 GSIAVESEPGvGTQFFVQIPWD 536
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
467-578 |
8.85e-08 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 55.33 E-value: 8.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 467 PAWVRGDAIRLEQVLINLLRNALdamadKRYKRLEI--RIEAD-GQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEG 543
Cdd:PRK11091 389 PHKVITDGTRLRQILWNLISNAV-----KFTQQGGVtvRVRYEeGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDSHGG 463
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1852262400 544 L-----GLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLP 578
Cdd:PRK11091 464 KpatgtGIGLAVSKRLAQAMGGDITVTSEEGkGSCFTLTIH 504
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
347-578 |
1.11e-07 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 54.19 E-value: 1.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 347 LRTAQEGLvqSAKLAALGQMSAAMAHEINQPLTTQRMQLETVRLLLDNGRPAEARQALEPLEQMLTR----MAALTSHLK 422
Cdd:PRK09303 137 LRQENETL--LEQLKFKDRVLAMLAHDLRTPLTAASLALETLELGQIDEDTELKPALIEQLQDQARRqleeIERLITDLL 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 423 TFARNSPMGLR---ERLDLATVVDQALHLLETRIRSEEVEVALYLAR--PAwVRGDAIRLEQVLINLLRNALdamadkRY 497
Cdd:PRK09303 215 EVGRTRWEALRfnpQKLDLGSLCQEVILELEKRWLAKSLEIQTDIPSdlPS-VYADQERIRQVLLNLLDNAI------KY 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 498 --KRLEIRIEA---DGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVG--EGLGLGLAISYGIVHEVGGQLQAE-NLSG 569
Cdd:PRK09303 288 tpEGGTITLSMlhrTTQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDEgtEGYGIGLSVCRRIVRVHYGQIWVDsEPGQ 367
|
....*....
gi 1852262400 570 GARLSLTLP 578
Cdd:PRK09303 368 GSCFHFTLP 376
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
362-426 |
4.03e-07 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 47.18 E-value: 4.03e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1852262400 362 ALGQMSAAMAHEINQPLTTQRMQLEtvrLLLDNGRPAEARQALEPLEQMLTRMAALTSHLKTFAR 426
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLE---LLLDTELSEEQREYLETILREAERLLRLINDLLDLSR 62
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
473-578 |
6.41e-07 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 48.26 E-value: 6.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALDAMADKryKRLEIRIEA-DGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGE----GLGLG 547
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDG--GRIRCILEKfRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTrahgGTGLG 78
|
90 100 110
....*....|....*....|....*....|..
gi 1852262400 548 LAISYGIVHEVGGQLQAENLS-GGARLSLTLP 578
Cdd:cd16925 79 LSIVKEFVELHGGTVTVSDAPgGGALFQVELP 110
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
362-581 |
2.22e-06 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 50.89 E-value: 2.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 362 ALGQMSAAMAHEINQPLTTQRMQLEtvrLLLDNGRPAEARQALEPL-----EQMLTRMAALTSHLKTFARNSPMGlRERL 436
Cdd:PRK09959 711 AKSQFLATMSHEIRTPISSIMGFLE---LLSGSGLSKEQRVEAISLayatgQSLLGLIGEILDVDKIESGNYQLQ-PQWV 786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 437 DLATVVDQALHLLETRIRSEEVEVALYLARPA--WVRGDAIRLEQVLINLLRNALDAMADKRYKRLE--IRIEADGQRWR 512
Cdd:PRK09959 787 DIPTLVQNTCHSFGAIAASKSIALSCSSTFPDhyLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTslGHIDDNHAVIK 866
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1852262400 513 LSVLDSGGGIAEADLAKVFDPFFTTKPVGE--GLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLPQDL 581
Cdd:PRK09959 867 MTIMDSGSGLSQEEQQQLFKRYSQTSAGRQqtGSGLGLMICKELIKNMQGDLSLESHPGiGTTFTITIPVEI 938
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
477-578 |
2.56e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 46.23 E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 477 LEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFF--TTKPVGEGLGLGLAISYGI 554
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPEN--TRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYrgDNSRNTEGAGLGLSIAKAI 78
|
90 100
....*....|....*....|....
gi 1852262400 555 VHEVGGQLQAENLSGGARLSLTLP 578
Cdd:cd16923 79 IELHGGSASAEYDDNHDLFKVRLP 102
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
473-578 |
1.49e-05 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 47.38 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 473 DAIRLEQVLINLLRNALDAMADKRYK-----RLEIRIEADGQRWRLS----VLDSGGGIAEADLAKVFDPFFTTKPvgEG 543
Cdd:PRK11073 234 DPDQIEQVLLNIVRNALQALGPEGGTitlrtRTAFQLTLHGERYRLAaridIEDNGPGIPPHLQDTLFYPMVSGRE--GG 311
|
90 100 110
....*....|....*....|....*....|....*
gi 1852262400 544 LGLGLAISYGIVHEVGGQLQAENLSGGARLSLTLP 578
Cdd:PRK11073 312 TGLGLSIARNLIDQHSGKIEFTSWPGHTEFSVYLP 346
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
368-581 |
5.48e-05 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 45.77 E-value: 5.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 368 AAMAHEINQPLTTQRMQLEtvrLLLDNGRPAEARQ-ALEPLEQMLTRMAALTSHLKTFAR--NSPMglrerLDLATVVD- 443
Cdd:PRK11006 209 ANVSHELRTPLTVLQGYLE---MMQDQPLEGALREkALHTMREQTQRMEGLVKQLLTLSKieAAPT-----IDLNEKVDv 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 444 -QALHLL--ETRIRSEEVEVALYLARPAW-VRGDAIRLEQVLINLLRNALDAMADKryKRLEIRIEADGQRWRLSVLDSG 519
Cdd:PRK11006 281 pMMLRVLerEAQTLSQGKHTITFEVDNSLkVFGNEDQLRSAISNLVYNAVNHTPEG--THITVRWQRVPQGAEFSVEDNG 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1852262400 520 GGIAEADLAKVFDPFF-----TTKPVGeGLGLGLAISYGIVHEVGGQLQAENLSG-GARLSLTLPQDL 581
Cdd:PRK11006 359 PGIAPEHIPRLTERFYrvdkaRSRQTG-GSGLGLAIVKHALSHHDSRLEIESEVGkGTRFSFVLPERL 425
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
469-577 |
3.27e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 41.08 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 469 WVRGDairLEQVLINLLRNALdamadkRY--KRLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPFFTTKPVGEGLGL 546
Cdd:cd16954 33 GERND---LMELLGNLLDNAC------KWclEFVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQRPGQGL 103
|
90 100 110
....*....|....*....|....*....|..
gi 1852262400 547 GLAISYGIVHEVGGQLQAEN-LSGGARLSLTL 577
Cdd:cd16954 104 GLAIAKEIVEQYGGELSLSDsPLGGARFEVVF 135
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
499-578 |
1.69e-03 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 41.16 E-value: 1.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 499 RLEIRIEADGQRWRLSVLDSGGGIAEADLAKVFDPfFTTKPVGEGLGLG-----LAISYGivheVGGQLQAENLSG-GAR 572
Cdd:COG2972 361 TIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEE-LSSKGEGRGIGLRnvrerLKLYYG----EEYGLEIESEPGeGTT 435
|
....*.
gi 1852262400 573 LSLTLP 578
Cdd:COG2972 436 VTIRIP 441
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
95-578 |
9.58e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 38.73 E-value: 9.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 95 LERINGAANSSTLELLDRTGLAVAASNWRLPSTYVGSNYGFRPYFKQTRSQGTGRFYAVGVTSGVPGYFLASAVNDEHGR 174
Cdd:COG3920 5 LLLLLLLALAALLLLAALLLLAAALLLALLALLLLALLLLALLLASALLALLALSAAALAAALAVALAAAVGAAAALLAL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 175 FLGAMVVKLEFPELEREWRQGSDILLVSDARGITFIANQDGWRYRELQPLSGADRAELAETRQYDKQPLVPLHHQVLTRF 254
Cdd:COG3920 85 LVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAALLLLA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 255 AANSTLSRVQGPDGSAEYLWESLPLAGEGWTLHLLRKPQVAADGRNAALGAAAVWLSLVFAALFISQRLRLARLRQRSRE 334
Cdd:COG3920 165 EELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEELERR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 335 ELKRQVEERTRELRTAQEGLVQSAKLAALGQMSAAMAHEINQPLTTQRMQLET-------------------VRLLLDNG 395
Cdd:COG3920 245 RRARGLGRLLLLLLLLLLLLRALLLLAAGIRLVITERKRAEEELEASLEEKELllrelhhrvknnlqvvsslLRLQARRA 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 396 RPAEARQALEPLEQmltRMAAL-TSHLKTFARNSpmglRERLDLATVVDQALHLLETRIRSEEVEVALylarpawvRGDA 474
Cdd:COG3920 325 DDPEAREALEESQN---RIQALaLVHELLYQSED----WEGVDLRDYLRELLEPLRDSYGGRGIRIEL--------DGPD 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1852262400 475 IRLEQ-------VLIN-LLRNALD-AMADKRYKRLEIRIEADGQRWRLSVLDSGGGIAEAdlakvfdpffTTKPVGEGLG 545
Cdd:COG3920 390 VELPAdaavplgLILNeLVTNALKhAFLSGEGGRIRVSWRREDGRLRLTVSDNGVGLPED----------VDPPARKGLG 459
|
490 500 510
....*....|....*....|....*....|...
gi 1852262400 546 LGLAisYGIVHEVGGQLQAENlSGGARLSLTLP 578
Cdd:COG3920 460 LRLI--RALVRQLGGTLELDR-PEGTRVRITFP 489
|
|
| |
