NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1860023047|ref|WP_175501720|]
View 

MULTISPECIES: ABC transporter permease [Enterobacterales]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-307 3.06e-98

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 291.97  E-value: 3.06e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIKFqnpDLGLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDF 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALL---GPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  81 GYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSF 160
Cdd:COG0601    78 GTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 161 QLRWIPVIN--------PSALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALL 232
Cdd:COG0601   158 KLGWLPVSGrvspwedfLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1860023047 233 PVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRLQ 307
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-307 3.06e-98

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 291.97  E-value: 3.06e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIKFqnpDLGLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDF 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALL---GPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  81 GYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSF 160
Cdd:COG0601    78 GTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 161 QLRWIPVIN--------PSALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALL 232
Cdd:COG0601   158 KLGWLPVSGrvspwedfLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1860023047 233 PVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRLQ 307
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-314 1.20e-55

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 182.97  E-value: 1.20e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIKFQNPDLGLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDF 80
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  81 GYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSF 160
Cdd:PRK10352   81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 161 QLRWIPVINPSALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGL 240
Cdd:PRK10352  161 YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGM 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1860023047 241 LLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRLQSIAGGHR 314
Cdd:PRK10352  241 HIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA 314
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 116-306 2.82e-19

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 83.50  E-value: 2.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 116 AFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSFqlrwipvinpSALQGLILPVITVAIPISAPLAQIL 195
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL----------SILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 196 LRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVA 275
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1860023047 276 VLQAVVMISALAFVLINLLVDALMPLFDPRL 306
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 98-296 2.20e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.30  E-value: 2.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  98 LPATLQLALLGFALATIIAFALAALSRLPAlRFLRSVLQSVPALFISLPTFWLGIALIQLFSFQLRWipvinpSALQGLI 177
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKR-GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------GILPGLG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 178 LPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFG 257
Cdd:cd06261    74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1860023047 258 LSGVGQLTqqaVNNQDVAVLQAVVMISALAFVLINLLVD 296
Cdd:cd06261   154 GEAPGPGT---GLLLIFAILFPGDLGVAAAVALILLLLS 189
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-307 3.06e-98

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 291.97  E-value: 3.06e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIKFqnpDLGLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDF 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALL---GPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  81 GYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSF 160
Cdd:COG0601    78 GTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 161 QLRWIPVIN--------PSALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALL 232
Cdd:COG0601   158 KLGWLPVSGrvspwedfLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALI 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1860023047 233 PVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRLQ 307
Cdd:COG0601   238 PVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-314 1.20e-55

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 182.97  E-value: 1.20e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIKFQNPDLGLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDF 80
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  81 GYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSF 160
Cdd:PRK10352   81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 161 QLRWIPVINPSALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGL 240
Cdd:PRK10352  161 YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGM 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1860023047 241 LLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRLQSIAGGHR 314
Cdd:PRK10352  241 HIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA 314
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 22-304 1.51e-47

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 161.81  E-value: 1.51e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  22 LSFFLLQVLPGD-AVLIKFQNPDlglsPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDFGYSVQAGVPVSEQLISNLPA 100
Cdd:PRK15081   22 LVFLFVHLLPGDpARLAAGPEAD----AQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVSRRPVSEEIASRFMP 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 101 TLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSFQLRWIPVINPSALQGLILPV 180
Cdd:PRK15081   98 TLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLPTVGADSWQHYILPS 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 181 ITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFGLSG 260
Cdd:PRK15081  178 LTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPG 257

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1860023047 261 VGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDP 304
Cdd:PRK15081  258 LGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINP 301
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
60-304 3.63e-45

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 155.77  E-value: 3.63e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  60 ADNPLWQQYVHTLLAMLRGDFGYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVP 139
Cdd:COG4168    36 SDASLFSGYLFYLQNLLQGDFGISSINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLS 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 140 ALFISLPTFWLGIALIQLFSFQLRWIPV---INP----------------------------SALQGLILPVITVAIPIS 188
Cdd:COG4168   116 LLGFSIPVFWLALLLILFFSLNLGWLPVsgrYNLlyeippvtgfalidawlsdspyrlkaiqSALQHLILPTLVLAVAPT 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 189 APLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQA 268
Cdd:COG4168   196 TEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINA 275

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1860023047 269 VNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDP 304
Cdd:COG4168   276 IRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNP 311
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-307 1.10e-40

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 144.57  E-value: 1.10e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIkfQNPDLGLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDF 80
Cdd:PRK10914    1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMI--MAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  81 GYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSF 160
Cdd:PRK10914   79 GISLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 161 QLRWIPV------------INP-------------------SALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVA 209
Cdd:PRK10914  159 HWNLTPVsgrvsdmvflddSNPltgfmlidtaiwgedgnfiDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIR 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 210 VARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFV 289
Cdd:PRK10914  239 TARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMII 318

                         330
                  ....*....|....*...
gi 1860023047 290 LINLLVDALMPLFDPRLQ 307
Cdd:PRK10914  319 LVNLLVDLLYGVVNPRIR 336
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-307 7.76e-38

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 136.35  E-value: 7.76e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGdavlikfqNPDLG---LSPDQIAEMRLAYGADNPLWQQYVHTLLAMLR 77
Cdd:PRK09471    1 MLKFILRRCLEAIPTLFILITISFFMMRLAPG--------SPFTGertLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAH 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  78 GDFGYSVQ-AGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQ 156
Cdd:PRK09471   73 GDFGPSFKyKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 157 LFSFQLRWIPV--INPSALQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPV 234
Cdd:PRK09471  153 IFAITLHWLPGggWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPV 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1860023047 235 LNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRLQ 307
Cdd:PRK09471  233 LSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK15110 PRK15110
peptide ABC transporter permease SapB;
64-304 1.26e-28

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 112.09  E-value: 1.26e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  64 LWQQYVHTLLAMLRGDFGYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALAALSRLPALRFLRSVLQSVPALFI 143
Cdd:PRK15110   40 LWDAWVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGF 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 144 SLPTFWLGIALIQLFSFQLRWIPV---------INP----------------------SALQGLILPVITVAIPISAPLA 192
Cdd:PRK15110  120 SIPVFWLALLLTLFFSLTLGWLPVsgrfdllyeVKPvtgfalidawlsdspwrdemimSAIRHMILPVITLAVAPTTEVI 199

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 193 QILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQ 272
Cdd:PRK15110  200 RLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQ 279

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1860023047 273 DVAVLQAVVMISALAFVLINLLVDALMPLFDP 304
Cdd:PRK15110  280 DYAAISAGVMVVGSLVIIVNVLSDILGAMANP 311
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 1-306 1.57e-24

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 101.75  E-value: 1.57e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGDAVLIKFQNPDL-----------------------------------G 45
Cdd:PRK15133    1 MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEFgqagglpgaggegvrashaqtgvgnisdsnyrggrG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  46 LSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGDFGYSVQAGVPVSEQLISNLPATLQLALLGFALATIIAFALA---AL 122
Cdd:PRK15133   81 LDPEVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGirkAV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 123 SRLPALRFLRSVLQSVPalfISLPTFWLGIALIQLFS-------FQLRWIPVINPSALQ----------GLILPVITVAI 185
Cdd:PRK15133  161 RNGSRFDVWSSAFIIIG---YAIPAFLFAILLIVFFAggsyfdlFPLRGLVSANFDSLPwyqkitdylwHITLPVLATVI 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 186 PISAPLAQILLRS-IDQVSTQpFVAVARAKGASESHVLWHHVMRNALLPVlnVAGL---LLGELIAGALITETVFGLSGV 261
Cdd:PRK15133  238 GGFAALTMLTKNSfLDEIRKQ-YVVTARAKGVSEKNILWKHVFRNAMLLV--IAGFpatFISMFFTGSLLIEVMFSLNGL 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 1860023047 262 GQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDALMPLFDPRL 306
Cdd:PRK15133  315 GLLGYEATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 116-306 2.82e-19

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 83.50  E-value: 2.82e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 116 AFALAALSRLPALRFLRSVLQSVPALFISLPTFWLGIALIQLFSFqlrwipvinpSALQGLILPVITVAIPISAPLAQIL 195
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL----------SILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 196 LRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFGLSGVGQLTQQAVNNQDVA 275
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1860023047 276 VLQAVVMISALAFVLINLLVDALMPLFDPRL 306
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 98-296 2.20e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.30  E-value: 2.20e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  98 LPATLQLALLGFALATIIAFALAALSRLPAlRFLRSVLQSVPALFISLPTFWLGIALIQLFSFQLRWipvinpSALQGLI 177
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKR-GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------GILPGLG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 178 LPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGALITETVFG 257
Cdd:cd06261    74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1860023047 258 LSGVGQLTqqaVNNQDVAVLQAVVMISALAFVLINLLVD 296
Cdd:cd06261   154 GEAPGPGT---GLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-105 6.68e-10

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 55.69  E-value: 6.68e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047   1 MQRSLLRRVGQSVLVLWAAFTLSFFLLQVLPGD-AVLIKFQNpdlgLSPDQIAEMRLAYGADNPLWQQYVHTLLAMLRGD 79
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDpARLACGKN----CTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGR 76

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1860023047  80 ------------FGYSVQAGVPVSEQLISNLPATLQLA 105
Cdd:pfam19300  77 dfgavghcpapcLGYSFANNEPVWDTIMDRFPTTLSLA 114
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 91-298 1.19e-06

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 48.99  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  91 SEQLISNLPATLQLALLGFALATIIAFALAALSRLpaLRFLRSVLQSVPALFISLPTF-WLGIALIqlfsfqlrWIPVIN 169
Cdd:COG0600    56 SGELWEHLLASLLRVLLGFALAALLGVPLGLLLGL--SRLLRRLLDPLLVFLRPIPPLaLAPLLIL--------WFGIGE 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 170 PSAlqglilpVITVAIPISAPLAQILLRSIDQVSTQpFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGELIAGA 249
Cdd:COG0600   126 ASK-------IFVIFLGAFFPILLNTAAGVRSVDPE-LLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGL 197

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1860023047 250 LITETVFGLSGVGQLTQQAVNNQDVAVLQAVVMISALAFVLINLLVDAL 298
Cdd:COG0600   198 VVAELLGASSGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLL 246
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 93-262 7.71e-06

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 46.64  E-value: 7.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047  93 QLISNLPATLQLALLGFALATIIAFALAALSRLpALRFLRSVLQSVPALFISLPTFWLGIALIQLFSfqlrwipvinpsa 172
Cdd:COG1173    73 RLLYGARISLLVGLLAVLIALVIGVLLGLLAGY-FGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG------------- 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 173 lQGLILPVITVAIPISAPLAQILLRSIDQVSTQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLllgeLIAGALIT 252
Cdd:COG1173   139 -PGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATL----GIASAILA 213

                         170
                  ....*....|
gi 1860023047 253 ETVFGLSGVG 262
Cdd:COG1173   214 EAGLSFLGLG 223
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
177-307 4.20e-03

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 38.26  E-value: 4.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1860023047 177 ILPVITVAIPISAPLAQILLRSIDQvstQPFVAVARAKGASESHVLWHHVMRNALLPVLNVAGLLLGeliaGALITETVF 256
Cdd:PRK09881  160 MLAIAIVRIPFYVRLARGQALVVRQ---YTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIG----SAILMAATL 232

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1860023047 257 GLSGVGQLTQQAVNNQDVAVLQ--------------AVVMISALAFvliNLLVDALMPLFDPRLQ 307
Cdd:PRK09881  233 GFIGLGAQQPSAEWGAMVANGRnyvldqwwycafpgAAILLTAVGF---NLFGDGIRDLLDPKAG 294
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH