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Conserved domains on  [gi|1863112389|ref|WP_176551567|]
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transposase, partial [Escherichia coli]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IS66_access_TnpA super family cl45815
IS66-like element accessory protein TnpA;
1-107 3.12e-17

IS66-like element accessory protein TnpA;


The actual alignment was detected with superfamily member NF038385:

Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 73.21  E-value: 3.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGrvsrrlpVTTSSDTGVELLPVEITPD-EQKEPVAAIAPS 79
Cdd:NF038385   93 FKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRNGL-------LQPDNEQETALLPVTLTPEpDPTIPVPAQDPE 165

                          90       100
                  ....*....|....*....|....*...
gi 1863112389  80 LStstQTRVSASSCKVEFRHGNMTLENP 107
Cdd:NF038385  166 QQ---NTTADSLCCELVLPAGTLRLFGP 190
 
Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
1-107 3.12e-17

IS66-like element accessory protein TnpA;


Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 73.21  E-value: 3.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGrvsrrlpVTTSSDTGVELLPVEITPD-EQKEPVAAIAPS 79
Cdd:NF038385   93 FKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRNGL-------LQPDNEQETALLPVTLTPEpDPTIPVPAQDPE 165

                          90       100
                  ....*....|....*....|....*...
gi 1863112389  80 LStstQTRVSASSCKVEFRHGNMTLENP 107
Cdd:NF038385  166 QQ---NTTADSLCCELVLPAGTLRLFGP 190
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-64 5.87e-11

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 54.55  E-value: 5.87e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGRVSRRLP-VTTSSDTGVELLPVEI 64
Cdd:COG2963    12 FKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPGDgRTTPEQAEIRRLRKEL 76
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 1-38 6.60e-08

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 46.19  E-value: 6.60e-08
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQ 38
Cdd:pfam01527  11 FKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYE 48
transpos_IS3 NF033516
IS3 family transposase;
1-44 9.73e-08

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 48.72  E-value: 9.73e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGRVS 44
Cdd:NF033516    2 FKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAA 45
 
Name Accession Description Interval E-value
IS66_access_TnpA NF038385
IS66-like element accessory protein TnpA;
1-107 3.12e-17

IS66-like element accessory protein TnpA;


Pssm-ID: 439678 [Multi-domain]  Cd Length: 190  Bit Score: 73.21  E-value: 3.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGrvsrrlpVTTSSDTGVELLPVEITPD-EQKEPVAAIAPS 79
Cdd:NF038385   93 FKIRLVEQTLQPGACVAQIARENGINDNLLFNWRHLYRNGL-------LQPDNEQETALLPVTLTPEpDPTIPVPAQDPE 165

                          90       100
                  ....*....|....*....|....*...
gi 1863112389  80 LStstQTRVSASSCKVEFRHGNMTLENP 107
Cdd:NF038385  166 QQ---NTTADSLCCELVLPAGTLRLFGP 190
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
1-64 5.87e-11

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 54.55  E-value: 5.87e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGRVSRRLP-VTTSSDTGVELLPVEI 64
Cdd:COG2963    12 FKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYREGGLGGFPGDgRTTPEQAEIRRLRKEL 76
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 1-38 6.60e-08

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 46.19  E-value: 6.60e-08
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQ 38
Cdd:pfam01527  11 FKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYE 48
transpos_IS3 NF033516
IS3 family transposase;
1-44 9.73e-08

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 48.72  E-value: 9.73e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1863112389   1 FKLQMVKLASQLGASVARIAREHDINDNLLFKWLRLWQNEGRVS 44
Cdd:NF033516    2 FKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRGGGEAA 45
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
 1-42 2.47e-04

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 36.42  E-value: 2.47e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1863112389   1 FKLQMVKLASQlGASVARIAREHDINDNLLFKWLRLWQNEGR 42
Cdd:pfam13518   1 ERLKIVLLALE-GESIKEAARLFGISRSTVYRWIRRYREGGL 41
HTH_23 pfam13384
Homeodomain-like domain;
2-41 1.94e-03

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 34.17  E-value: 1.94e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1863112389   2 KLQMVKLASQlGASVARIAREHDINDNLLFKWLRLWQNEG 41
Cdd:pfam13384   7 RARALLLLAE-GLSVKEIAELLGVSRRTVYRWLKRYNEEG 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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