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Conserved domains on  [gi|1865299825|ref|WP_177343916|]
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AAA family ATPase, partial [Klebsiella quasipneumoniae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13709 super family cl36287
conjugal transfer nickase/helicase TraI; Provisional
 1-113 2.48e-64

conjugal transfer nickase/helicase TraI; Provisional


The actual alignment was detected with superfamily member PRK13709:

Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 210.42  E-value: 2.48e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1865299825    1 TIQAQIRSGQLLNVPVAHGHGNDLLISRQTWDAEKSILTHVLEGKDAVAPLMDRVPASLMTDLTAGQRAATRMILESTDR 80
Cdd:PRK13709   906 EINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEGLTSGQRAATRMILESTDR 985

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1865299825   81 FTVVQGYAGVGKTTQFRAVMSAISLLPEETRPR 113
Cdd:PRK13709   986 FTVVQGYAGVGKTTQFRAVMSAVNTLPESERPR 1018
 
Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
 1-113 2.48e-64

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 210.42  E-value: 2.48e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1865299825    1 TIQAQIRSGQLLNVPVAHGHGNDLLISRQTWDAEKSILTHVLEGKDAVAPLMDRVPASLMTDLTAGQRAATRMILESTDR 80
Cdd:PRK13709   906 EINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEGLTSGQRAATRMILESTDR 985

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1865299825   81 FTVVQGYAGVGKTTQFRAVMSAISLLPEETRPR 113
Cdd:PRK13709   986 FTVVQGYAGVGKTTQFRAVMSAVNTLPESERPR 1018
TraI_TIGR TIGR02760
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ...
 2-113 1.54e-29

conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.


Pssm-ID: 274285 [Multi-domain]  Cd Length: 1960  Bit Score: 110.76  E-value: 1.54e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1865299825    2 IQAQIRSGQLLNVPVAHGHGN-DLLISRQTWDAEKSILTHVLEGKDAVAPLMDRVPA----SLMTDLTAGQRAATRMILE 76
Cdd:TIGR02760  954 IAAALKNRPKLYRLLSAEYGDgTRWTTRAALRTETSILLHILPGKETVTPLATRAQVflnlELLERLTHGQKQAIHLIIS 1033

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1865299825   77 STDRFTVVQGYAGVGKTTQFRAVMSAISLLPEETRPR 113
Cdd:TIGR02760 1034 TKDRFVAVQGLAGVGKTTMLESRYKPVLQAFESEQLQ 1070
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
 28-94 7.59e-09

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 51.52  E-value: 7.59e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1865299825  28 RQTWDAEKSILTHVLEGK------DAVAPLMDRVPASLMTDLTAGQRAATRMILeSTDRFTVVQGYAGVGKTT 94
Cdd:COG0507    84 TRLLEAEQRLARRLRRLArpaldeADVEAALAALEPRAGITLSDEQREAVALAL-TTRRVSVLTGGAGTGKTT 155
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
 66-103 2.32e-07

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 46.39  E-value: 2.32e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1865299825  66 GQRAATRMILEstDRFTVVQGYAGVGKTTQFRAVMSAI 103
Cdd:cd17933     1 EQKAAVRLVLR--NRVSVLTGGAGTGKTTTLKALLAAL 36
AAA_30 pfam13604
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 63-99 6.14e-07

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.


Pssm-ID: 433343 [Multi-domain]  Cd Length: 191  Bit Score: 45.63  E-value: 6.14e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1865299825  63 LTAGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAV 99
Cdd:pfam13604   2 LNAEQAAAVRALLTSGDRVAVLVGPAGTGKTTALKAL 38
 
Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
 1-113 2.48e-64

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 210.42  E-value: 2.48e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1865299825    1 TIQAQIRSGQLLNVPVAHGHGNDLLISRQTWDAEKSILTHVLEGKDAVAPLMDRVPASLMTDLTAGQRAATRMILESTDR 80
Cdd:PRK13709   906 EINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEGLTSGQRAATRMILESTDR 985

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1865299825   81 FTVVQGYAGVGKTTQFRAVMSAISLLPEETRPR 113
Cdd:PRK13709   986 FTVVQGYAGVGKTTQFRAVMSAVNTLPESERPR 1018
PRK14712 PRK14712
conjugal transfer nickase/helicase TraI; Provisional
 2-113 1.33e-47

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237796 [Multi-domain]  Cd Length: 1623  Bit Score: 162.34  E-value: 1.33e-47
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1865299825    2 IQAQIRSGQLLNVPVAHGHGNDLLISRQTWDAEKSILTHVLEGKDAVAPLMDRVPASLMTDLTAGQRAATRMILESTDRF 81
Cdd:PRK14712   775 INAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSGQRAATRMILETSDRF 854

                           90       100       110
                   ....*....|....*....|....*....|..
gi 1865299825   82 TVVQGYAGVGKTTQFRAVMSAISLLPEETRPR 113
Cdd:PRK14712   855 TVVQGYAGVGKTTQFRAVMSAVNMLPESERPR 886
TraI_TIGR TIGR02760
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ...
 2-113 1.54e-29

conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.


Pssm-ID: 274285 [Multi-domain]  Cd Length: 1960  Bit Score: 110.76  E-value: 1.54e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1865299825    2 IQAQIRSGQLLNVPVAHGHGN-DLLISRQTWDAEKSILTHVLEGKDAVAPLMDRVPA----SLMTDLTAGQRAATRMILE 76
Cdd:TIGR02760  954 IAAALKNRPKLYRLLSAEYGDgTRWTTRAALRTETSILLHILPGKETVTPLATRAQVflnlELLERLTHGQKQAIHLIIS 1033

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1865299825   77 STDRFTVVQGYAGVGKTTQFRAVMSAISLLPEETRPR 113
Cdd:TIGR02760 1034 TKDRFVAVQGLAGVGKTTMLESRYKPVLQAFESEQLQ 1070
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
 28-94 7.59e-09

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 51.52  E-value: 7.59e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1865299825  28 RQTWDAEKSILTHVLEGK------DAVAPLMDRVPASLMTDLTAGQRAATRMILeSTDRFTVVQGYAGVGKTT 94
Cdd:COG0507    84 TRLLEAEQRLARRLRRLArpaldeADVEAALAALEPRAGITLSDEQREAVALAL-TTRRVSVLTGGAGTGKTT 155
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
 66-103 2.32e-07

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 46.39  E-value: 2.32e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1865299825  66 GQRAATRMILEstDRFTVVQGYAGVGKTTQFRAVMSAI 103
Cdd:cd17933     1 EQKAAVRLVLR--NRVSVLTGGAGTGKTTTLKALLAAL 36
AAA_30 pfam13604
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 63-99 6.14e-07

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.


Pssm-ID: 433343 [Multi-domain]  Cd Length: 191  Bit Score: 45.63  E-value: 6.14e-07
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1865299825  63 LTAGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAV 99
Cdd:pfam13604   2 LNAEQAAAVRALLTSGDRVAVLVGPAGTGKTTALKAL 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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