|
Name |
Accession |
Description |
Interval |
E-value |
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
3-220 |
4.99e-118 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 335.47 E-value: 4.99e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELT 82
Cdd:COG1136 2 SPLLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 83 KYRRDHVGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAK 157
Cdd:COG1136 82 RLRRRHIGFVFQFFNLLPELTALENVALPLLLAGVSrkerrERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVN 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 158 RPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIAR 220
Cdd:COG1136 162 RPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAARADRVIRLRDGRIVS 224
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
7-218 |
6.27e-107 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 307.11 E-value: 6.27e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRR 86
Cdd:cd03255 2 ELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:cd03255 82 RHIGFVFQSFNLLPDLTALENVELPLLLAGVPkkerrERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPKI 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:cd03255 162 ILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEYADRIIELRDGKI 218
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-227 |
3.34e-87 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 257.75 E-value: 3.34e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE 80
Cdd:COG4181 4 SSAPIIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYRRDHVGFVFQFYNLVPSLTAYENVALVTEVAKSP---MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAK 157
Cdd:COG4181 84 RARLRARHVGFVFQSFQLLPTLTALENVMLPLELAGRRdarARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFAT 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 158 RPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIARVRTNEVR 227
Cdd:COG4181 164 EPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAARCDRVLRLRAGRLVEDTAATAA 233
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
12-226 |
1.23e-76 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 230.71 E-value: 1.23e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 12 TKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdHVGF 91
Cdd:COG2884 8 SKRYPGG---REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYLRR-RIGV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 92 VFQFYNLVPSLTAYENVALVTEVAKSPMRPA-----DALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:COG2884 84 VFQDFRLLPDRTVYENVALPLRVTGKSRKEIrrrvrEVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLLADE 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNRqLGTTTVIITHNAS-IQGVADRVLFFADGRIARVRTNEV 226
Cdd:COG2884 164 PTGNLDPETSWEIMELLEEINR-RGTTVLIATHDLElVDRMPKRVLELEDGRLVRDEARGV 223
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
9-218 |
1.18e-73 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 223.23 E-value: 1.18e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdH 88
Cdd:cd03258 5 KNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKARR-R 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:cd03258 84 IGMIFQHFNLLSSRTVFENVALPLEIAGVPKaeieeRVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKVLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:cd03258 164 CDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEvVKRICDRVAVMEKGEV 219
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
9-218 |
1.19e-73 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 226.88 E-value: 1.19e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDh 88
Cdd:COG1135 5 ENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAARRK- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:COG1135 84 IGMIFQHFNLLSSRTVAENVALPLEIAGVPKaeirkRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPKVLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:COG1135 164 CDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDvVRRICDRVAVLENGRI 219
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
7-218 |
1.18e-70 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 216.01 E-value: 1.18e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeLEDRELTKYRR 86
Cdd:COG1126 3 EIENLHKSF--GDLEV--LKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLT-DSKKDINKLRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dHVGFVFQFYNLVPSLTAYENV--ALVTeVAKspMRPADA-------LALVGLEERMHHFPAQLSGGEQQRVAIARAIAK 157
Cdd:COG1126 78 -KVGMVFQQFNLFPHLTVLENVtlAPIK-VKK--MSKAEAeeramelLERVGLADKADAYPAQLSGGQQQRVAIARALAM 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 158 RPAVLLCDEPTGALDSktgiRVIEALLGVNRQL---GTTTVIITHN---AsiQGVADRVLFFADGRI 218
Cdd:COG1126 154 EPKVMLFDEPTSALDP----ELVGEVLDVMRDLakeGMTMVVVTHEmgfA--REVADRVVFMDGGRI 214
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-231 |
8.67e-70 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 214.57 E-value: 8.67e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldltELEDRE 80
Cdd:COG1116 3 AAAPALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEV--------LVDGKP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYRRDhVGFVFQFYNLVPSLTAYENVALVTEVAKSPMRPA-----DALALVGLEERMHHFPAQLSGGEQQRVAIARAI 155
Cdd:COG1116 75 VTGPGPD-RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERrerarELLELVGLAGFEDAYPHQLSGGMRQRVAIARAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 156 AKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNasiqgV------ADRVLFFAD--GRIARV------ 221
Cdd:COG1116 154 ANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHD-----VdeavflADRVVVLSArpGRIVEEidvdlp 228
|
250
....*....|..
gi 1869873813 222 --RTNEVRREAA 231
Cdd:COG1116 229 rpRDRELRTSPE 240
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-219 |
2.43e-66 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 208.80 E-value: 2.43e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEL--ED 78
Cdd:COG3842 1 MAMPALELENVSKRY--GDV--TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLppEK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 79 ReltkyrrdHVGFVFQFYNLVPSLTAYENVA--L-VTEVAKSPMRP--ADALALVGLEERMHHFPAQLSGGEQQRVAIAR 153
Cdd:COG3842 77 R--------NVGMVFQDYALFPHLTVAENVAfgLrMRGVPKAEIRArvAELLELVGLEGLADRYPHQLSGGQQQRVALAR 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 154 AIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNasiQG----VADRVLFFADGRIA 219
Cdd:COG3842 149 ALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHD---QEealaLADRIAVMNDGRIE 215
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
6-218 |
6.59e-66 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 202.76 E-value: 6.59e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 6 FSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeLEDRELTKYR 85
Cdd:cd03262 1 IEIKNLHKSFGDFHV----LKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLT-DDKKNINELR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 RdHVGFVFQFYNLVPSLTAYENVAL-VTEVAKSPMRPADALAL-----VGLEERMHHFPAQLSGGEQQRVAIARAIAKRP 159
Cdd:cd03262 76 Q-KVGMVFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALellekVGLADKADAYPAQLSGGQQQRVAIARALAMNP 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 160 AVLLCDEPTGALDSKtgirVIEALLGVNRQL---GTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:cd03262 155 KVMLFDEPTSALDPE----LVGEVLDVMKDLaeeGMTMVVVTHEMGfAREVADRVIFMDDGRI 213
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-218 |
6.68e-66 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 203.67 E-value: 6.68e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVKVHalNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE 80
Cdd:COG1127 1 MSEPMIEVRNLTKSF--GDRVVL--DGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYRRdHVGFVFQFYNLVPSLTAYENVALvtevaksPMR-----PAD--------ALALVGLEERMHHFPAQLSGGEQQ 147
Cdd:COG1127 77 LYELRR-RIGMLFQGGALFDSLTVFENVAF-------PLRehtdlSEAeirelvleKLELVGLPGAADKMPSELSGGMRK 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 148 RVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG1127 149 RVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDlDSAFAIADRVAVLADGKI 220
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
9-218 |
1.35e-65 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 206.58 E-value: 1.35e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDh 88
Cdd:PRK11153 5 KNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKARRQ- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:PRK11153 84 IGMIFQHFNLLSSRTVFDNVALPLELAGTPkaeikARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:PRK11153 164 CDEATSALDPATTRSILELLKDINRELGLTIVLITHEmDVVKRICDRVAVIDAGRL 219
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
9-221 |
1.28e-64 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 199.67 E-value: 1.28e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSgevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELedrelTKYRRDh 88
Cdd:cd03259 4 KGLSKTYGS----VRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGV-----PPERRN- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:cd03259 74 IGMVFQDYALFPHLTVAENIAFGLKLRGVPkaeirARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARV 221
Cdd:cd03259 154 LDEPLSALDAKLREELREELKELQRELGITTIYVTHDqEEALALADRIAVMNEGRIVQV 212
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
7-225 |
4.36e-64 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 198.46 E-value: 4.36e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEledreltkyRR 86
Cdd:cd03293 2 EVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG---------PG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:cd03293 73 PDRGYVFQQDALLPWLTVLDNVALGLELQGVPKaeareRAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS--IQgVADRVLFFA--DGRIARVRTNE 225
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDeaVF-LADRVVVLSarPGRIVAEVEVD 219
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
4-218 |
1.12e-63 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 198.36 E-value: 1.12e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 4 AVFSAKALTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTK 83
Cdd:COG3638 1 PMLELRNLSKRYPGG---TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 84 YRRDhVGFVFQFYNLVPSLTAYENV------------ALVTEVAKS-PMRPADALALVGLEERMHHFPAQLSGGEQQRVA 150
Cdd:COG3638 78 LRRR-IGMIFQQFNLVPRLSVLTNVlagrlgrtstwrSLLGLFPPEdRERALEALERVGLADKAYQRADQLSGGQQQRVA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 151 IARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:COG3638 157 IARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLaRRYADRIIGLRDGRV 225
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
11-217 |
2.56e-62 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 194.00 E-value: 2.56e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdHVG 90
Cdd:TIGR02673 7 VSKAYPGG---VAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPLLRR-RIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVA-----KSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:TIGR02673 83 VVFQDFRLLPDRTVYENVALPLEVRgkkerEIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLAD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 166 EPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:TIGR02673 163 EPTGNLDPDLSERILDLLKRLNKR-GTTVIVATHDLSlVDRVAHRVIILDDGR 214
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
11-219 |
5.04e-60 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 188.93 E-value: 5.04e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdHVG 90
Cdd:cd03256 6 LSKTYPNG---KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRR-QIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVaLVTEVA-KSPMR-------PAD------ALALVGLEERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:cd03256 82 MIFQQFNLIERLSVLENV-LSGRLGrRSTWRslfglfpKEEkqralaALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVLFFADGRIA 219
Cdd:cd03256 161 QQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLaREYADRIVGLKDGRIV 224
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
12-218 |
1.05e-59 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 187.23 E-value: 1.05e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 12 TKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdHVGF 91
Cdd:cd03292 7 TKTYPNG---TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRR-KIGV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 92 VFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:cd03292 83 VFQDFRLLPDRNVYENVAFALEVTGVPpreirKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADE 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNrQLGTTTVIITHNASIqgVAD---RVLFFADGRI 218
Cdd:cd03292 163 PTGNLDPDTTWEIMNLLKKIN-KAGTTVVVATHAKEL--VDTtrhRVIALERGKL 214
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
9-217 |
1.36e-59 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 185.47 E-value: 1.36e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVsgevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTkyRRDH 88
Cdd:cd03229 4 KNVSKRYG----QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPP--LRRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVtevakspmrpadalalvgleermhhfpaqLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:cd03229 78 IGMVFQDFALFPHLTVLENIALG-----------------------------LSGGQQQRVALARALAMDPDVLLLDEPT 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGR 217
Cdd:cd03229 129 SALDPITRREVRALLKSLQAQLGITVVLVTHDlDEAARLADRVVVLRDGK 178
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
7-218 |
1.55e-59 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 187.33 E-value: 1.55e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELeDRELTKYRR 86
Cdd:cd03257 3 EVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKL-SRRLRKIRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQ--FYNLVPSLTAYENVA-----LVTEVAKSPMRPADALALVGL---EERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:cd03257 82 KEIQMVFQdpMSSLNPRMTIGEQIAeplriHGKLSKKEARKEAVLLLLVGVglpEEVLNRYPHELSGGQRQRVAIARALA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:cd03257 162 LNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGvVAKIADRVAVMYAGKI 224
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-218 |
2.18e-59 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 195.12 E-value: 2.18e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVK-VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDR 79
Cdd:COG1123 256 AAEPLLEVRNLSKRYPVRGKGgVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRR 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELTKYRRdHVGFVFQ--FYNLVPSLTAYENVAL------VTEVAKSPMRPADALALVGLEER-MHHFPAQLSGGEQQRVA 150
Cdd:COG1123 336 SLRELRR-RVQMVFQdpYSSLNPRMTVGDIIAEplrlhgLLSRAERRERVAELLERVGLPPDlADRYPHELSGGQRQRVA 414
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 151 IARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG1123 415 IARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDlAVVRYIADRVAVMYDGRI 483
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
9-218 |
3.21e-59 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 186.55 E-value: 3.21e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdH 88
Cdd:cd03261 4 RGLTKSF--GGRTV--LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLRR-R 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVAL------------VTEVAkspmrpADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:cd03261 79 MGMLFQSGALFDSLTVFENVAFplrehtrlseeeIREIV------LEKLEAVGLRGAEDLYPAELSGGMKKRVALARALA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:cd03261 153 LDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDlDTAFAIADRIAVLYDGKI 215
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
9-218 |
4.45e-59 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 189.90 E-value: 4.45e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsGevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkyrRDh 88
Cdd:COG3839 7 ENVSKSY--G--GVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD-----RN- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:COG3839 77 IAMVFQSYALYPHMTVYENIAFPLKLRKVPkaeidRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNasiQ----GVADRVLFFADGRI 218
Cdd:COG3839 157 LDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTHD---QveamTLADRIAVMNDGRI 212
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
2-218 |
7.38e-59 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 185.75 E-value: 7.38e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 2 SEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREL 81
Cdd:PRK10584 3 AENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 82 TKYRRDHVGFVFQFYNLVPSLTAYENVALVTEV-----AKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:PRK10584 83 AKLRAKHVGFVFQSFMLIPTLNALENVELPALLrgessRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK10584 163 GRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRLRLVNGQL 224
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
6-219 |
5.22e-58 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 183.30 E-value: 5.22e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 6 FSAKALTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyr 85
Cdd:COG1122 1 IELENLSFSYPGG---TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLREL---- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 RDHVGFVFQFYN--LVpSLTAYENVAL--------VTEVAKspmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAI 155
Cdd:COG1122 74 RRKVGLVFQNPDdqLF-APTVEEDVAFgpenlglpREEIRE---RVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 156 AKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:COG1122 150 AMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDlVAELADRVIVLDDGRIV 213
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
9-218 |
7.66e-57 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 180.96 E-value: 7.66e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdH 88
Cdd:TIGR02315 5 ENLSKVYPNG---KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKLRR-R 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVaLVTEVAKSP--------------MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARA 154
Cdd:TIGR02315 81 IGMIFQHYNLIERLTVLENV-LHGRLGYKPtwrsllgrfseedkERALSALERVGLADKAYQRADQLSGGQQQRVAIARA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 155 IAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:TIGR02315 160 LAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLaKKYADRIVGLKAGEI 224
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
11-218 |
7.74e-57 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 180.78 E-value: 7.74e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVG 90
Cdd:PRK11629 11 LCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKspMRPADA-------LALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:PRK11629 91 FIYQFHHLLPDFTALENVAMPLLIGK--KKPAEInsralemLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVL 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK11629 169 ADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRL 223
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
9-223 |
9.78e-57 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 180.13 E-value: 9.78e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGevkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreltKYRRdH 88
Cdd:cd03300 4 ENVSKFYGGF----VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLP-----PHKR-P 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:cd03300 74 VNTVFQNYALFPHLTVFENIAFGLRLKKLPkaeikERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIARVRT 223
Cdd:cd03300 154 LDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEeALTMSDRIAVMNKGKIQQIGT 214
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
23-223 |
1.51e-56 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 183.42 E-value: 1.51e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDL-TELEDREltkyRRdhVGFVFQFYNLVPS 101
Cdd:COG1118 16 TLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRE----RR--VGFVFQHYALFPH 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVALVTEVAKSPMRPADA-----LALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKtg 176
Cdd:COG1118 90 MTVAENIAFGLRVRPPSKAEIRArveelLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPFGALDAK-- 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 177 IRV-IEALL-GVNRQLGTTTVIITHNasiQ----GVADRVLFFADGRIARVRT 223
Cdd:COG1118 168 VRKeLRRWLrRLHDELGGTTVFVTHD---QeealELADRVVVMNQGRIEQVGT 217
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
4-231 |
3.92e-56 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 189.16 E-value: 3.92e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 4 AVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTK 83
Cdd:PRK10535 3 ALLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 84 YRRDHVGFVFQFYNLVPSLTAYENVALV-----TEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKR 158
Cdd:PRK10535 83 LRREHFGFIFQRYHLLSHLTAAQNVEVPavyagLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNG 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 159 PAVLLCDEPTGALDSKTGIRVIeALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIARVRTNEVRREAA 231
Cdd:PRK10535 163 GQVILADEPTGALDSHSGEEVM-AILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAQEKVNVA 234
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
23-212 |
6.51e-56 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 177.42 E-value: 6.51e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQFYNLVPSL 102
Cdd:TIGR03608 12 VILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRREKLGYLFQNFALIENE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYEN--VALV-TEVAKSPMRPA--DALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:TIGR03608 92 TVEENldLGLKyKKLSKKEKREKkkEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADEPTGSLDPKNRD 171
|
170 180 190
....*....|....*....|....*....|....*
gi 1869873813 178 RVIEALLGVNRQlGTTTVIITHNASIQGVADRVLF 212
Cdd:TIGR03608 172 EVLDLLLELNDE-GKTIIIVTHDPEVAKQADRVIE 205
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
9-219 |
2.14e-55 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 177.21 E-value: 2.14e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLT--ELEDRELtkyrR 86
Cdd:PRK09493 5 KNVSKHF--GPTQV--LHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpKVDERLI----R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQFYNLVPSLTAYENVAL-VTEVAKSPMRPADALAL-----VGLEERMHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:PRK09493 77 QEAGMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARellakVGLAERAHHYPSELSGGQQQRVAIARALAVKPK 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 161 VLLCDEPTGALDSKTGIRViealLGVNRQL---GTTTVIITHNASI-QGVADRVLFFADGRIA 219
Cdd:PRK09493 157 LMLFDEPTSALDPELRHEV----LKVMQDLaeeGMTMVIVTHEIGFaEKVASRLIFIDKGRIA 215
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
24-223 |
7.63e-55 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 175.61 E-value: 7.63e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkyrrDHVGFVFQFYNLVPSLT 103
Cdd:cd03296 17 ALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE------RNVGFVFQHYALFRHMT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAKSPMRPADA---------LALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSK 174
Cdd:cd03296 91 VFDNVAFGLRVKPRSERPPEAeirakvhelLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAK 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 175 TGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARVRT 223
Cdd:cd03296 171 VRKELRRWLRRLHDELHVTTVFVTHDqEEALEVADRVVVMNKGRIEQVGT 220
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
7-217 |
8.97e-55 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 174.58 E-value: 8.97e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrR 86
Cdd:cd03225 1 ELKNLSFSYPDGARP--ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKEL----R 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQ-----FYNLvpslTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:cd03225 75 RKVGLVFQnpddqFFGP----TVEEEVAFGLENLGLPeeeieERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:cd03225 151 MDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDlLLELADRVIVLEDGK 211
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
7-225 |
1.12e-53 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 173.07 E-value: 1.12e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkYRR 86
Cdd:COG1124 3 EVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKA---FRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DhVGFVFQFY--NLVPSLTAYENVA---LVTEVAKSPMRPADALALVGLEER-MHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:COG1124 80 R-VQMVFQDPyaSLHPRHTVDRILAeplRIHGLPDREERIAELLEQVGLPPSfLDRYPHQLSGGQRQRVAIARALILEPE 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 161 VLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARVRTNE 225
Cdd:COG1124 159 LLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDlAVVAHLCDRVAVMQNGRIVEELTVA 224
|
|
| ABC_MetN |
TIGR02314 |
D-methionine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding ... |
9-218 |
1.14e-53 |
|
D-methionine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of the D-methionine ABC transporter complex. Known members belong to the Proteobacteria.
Pssm-ID: 131367 [Multi-domain] Cd Length: 343 Bit Score: 175.84 E-value: 1.14e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdH 88
Cdd:TIGR02314 5 SNITKVFHQGTKTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTSGSVIVDGQDLTTLSNSELTKARR-Q 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:TIGR02314 84 IGMIFQHFNLLSSRTVFGNVALPLELDNTPkdeikRKVTELLALVGLGDKHDSYPSNLSGGQKQRVAIARALASNPKVLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:TIGR02314 164 CDEATSALDPATTQSILELLKEINRRLGLTILLITHEMDvVKRICDCVAVISNGEL 219
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
24-223 |
1.35e-53 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 176.00 E-value: 1.35e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltkyRRDHvGFVFQFYNLVPSLT 103
Cdd:TIGR03265 19 ALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRLPPQ-----KRDY-GIVFQSYALFPNLT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVA--LVT------EVAKspmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:TIGR03265 93 VADNIAygLKNrgmgraEVAE---RVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLDEPLSALDARV 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 176 GIRVIEALLGVNRQLGTTTVIITHNasiQ----GVADRVLFFADGRIARVRT 223
Cdd:TIGR03265 170 REHLRTEIRQLQRRLGVTTIMVTHD---QeealSMADRIVVMNHGVIEQVGT 218
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
7-232 |
3.75e-53 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 171.01 E-value: 3.75e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYvsGevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeledRELTKYRR 86
Cdd:COG1131 2 EVRGLTKRY--G--DKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVA----RDPAEVRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dHVGFVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:COG1131 74 -RIGYVPQEPALYPDLTVRENLRFFARLYGLPRkeareRIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPEL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGRIARVRT-NEVRREAAE 232
Cdd:COG1131 153 LILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEeAERLCDRVAIIDKGRIVADGTpDELKARLLE 224
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
21-221 |
1.80e-52 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 168.59 E-value: 1.80e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkyrRDhVGFVFQFYNLVP 100
Cdd:cd03301 12 NVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD-----RD-IAMVFQNYALYP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:cd03301 86 HMTVYDNIAFGLKLRKVPKdeideRVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKL 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 176 GIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARV 221
Cdd:cd03301 166 RVQMRAELKRLQQRLGTTTIYVTHDqVEAMTMADRIAVMNDGQIQQI 212
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
24-225 |
5.09e-51 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 166.66 E-value: 5.09e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQFYNLVPSLT 103
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVFQSFALLPHRT 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIR 178
Cdd:cd03294 119 VLENVAFGLEVQGVPRaereeRAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRRE 198
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 179 VIEALLGVNRQLGTTTVIITH--NASIQgVADRVLFFADGRIARVRTNE 225
Cdd:cd03294 199 MQDELLRLQAELQKTIVFITHdlDEALR-LGDRIAIMKDGRLVQVGTPE 246
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
1-223 |
7.42e-51 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 169.36 E-value: 7.42e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEL--ED 78
Cdd:PRK09452 10 SLSPLVELRGISKSFDGKEV----ISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVpaEN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 79 ReltkyrrdHVGFVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIAR 153
Cdd:PRK09452 86 R--------HVNTVFQSYALFPHMTVFENVAFGLRMQKTPAaeitpRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIAR 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 154 AIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNasiQGVA----DRVLFFADGRIARVRT 223
Cdd:PRK09452 158 AVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHD---QEEAltmsDRIVVMRDGRIEQDGT 228
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
11-225 |
8.98e-50 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 162.86 E-value: 8.98e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEVkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVG 90
Cdd:cd03295 6 VTKRYGGGKK---AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVEL----RRKIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEER--MHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:cd03295 79 YVIQQIGLFPHMTVEENIALVPKLLKWPkekirERADELLALVGLDPAefADRYPHELSGGQQQRVGVARALAADPPLLL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNasIQG---VADRVLFFADGRIARVRTNE 225
Cdd:cd03295 159 MDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHD--IDEafrLADRIAIMKNGEIVQVGTPD 221
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
18-231 |
1.36e-48 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 162.95 E-value: 1.36e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 18 GEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkyrrDHVGFVFQFYN 97
Cdd:PRK10851 13 GRTQV--LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD------RKVGFVFQHYA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 LVPSLTAYENVALVTEVAKSPMRPADA---------LALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:PRK10851 85 LFRHMTVFDNIAFGLTVLPRRERPNAAaikakvtqlLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPF 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRIARVRT-NEVRREAA 231
Cdd:PRK10851 165 GALDAQVRKELRRWLRQLHEELKFTSVFVTHDQeEAMEVADRVVVMSQGNIEQAGTpDQVWREPA 229
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
7-211 |
2.42e-48 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 161.37 E-value: 2.42e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTL-LNIMGGLDRP--TSGSLFFRDLDLTELEDRELTK 83
Cdd:COG0444 3 EVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLaRAILGLLPPPgiTSGEILFDGEDLLKLSEKELRK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 84 YRRDHVGFVFQ--FYNLVPSLTAYEnvaLVTEVAKS--PMRPADA-------LALVGL---EERMHHFPAQLSGGEQQRV 149
Cdd:COG0444 83 IRGREIQMIFQdpMTSLNPVMTVGD---QIAEPLRIhgGLSKAEAreraielLERVGLpdpERRLDRYPHELSGGMRQRV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 150 AIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVL 211
Cdd:COG0444 160 MIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDlGVVAEIADRVA 222
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
21-221 |
2.91e-48 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 158.50 E-value: 2.91e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGL-----DRPTSGSLFFRDLDLTELEDRELTKYRRdhVGFVFQF 95
Cdd:cd03260 12 DKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDVLELRRR--VGMVFQK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLVPsLTAYENVA----LVTEVAKSPM--RPADALALVGLEERMHH--FPAQLSGGEQQRVAIARAIAKRPAVLLCDEP 167
Cdd:cd03260 90 PNPFP-GSIYDNVAyglrLHGIKLKEELdeRVEEALRKAALWDEVKDrlHALGLSGGQQQRLCLARALANEPEVLLLDEP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 168 TGALDSkTGIRVIEALLgvnRQLG--TTTVIITHN-ASIQGVADRVLFFADGRIARV 221
Cdd:cd03260 169 TSALDP-ISTAKIEELI---AELKkeYTIVIVTHNmQQAARVADRTAFLLNGRLVEF 221
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
25-218 |
5.83e-48 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 156.90 E-value: 5.83e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreLTKYRRdHVGFVFQfynlVPSL-- 102
Cdd:COG4619 16 LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMP---PPEWRR-QVAYVPQ----EPALwg 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 -TAYENVALVTEVAKSPMRPADALAL---VGLEERMHHFPA-QLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:COG4619 88 gTVRDNLPFPFQLRERKFDRERALELlerLGLPPDILDKPVeRLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTR 167
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1869873813 178 RVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG4619 168 RVEELLREYLAEEGRAVLWVSHDpEQIERVADRVLTLEAGRL 209
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
9-218 |
1.18e-47 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 157.60 E-value: 1.18e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffRDLDLTELEDRELTKYR--- 85
Cdd:PRK11264 7 KNLVKKFHGQTV----LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTI--RVGDITIDTARSLSQQKgli 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 ---RDHVGFVFQFYNLVPSLTAYENV---ALVteVAKSPMRPADA-----LALVGLEERMHHFPAQLSGGEQQRVAIARA 154
Cdd:PRK11264 81 rqlRQHVGFVFQNFNLFPHRTVLENIiegPVI--VKGEPKEEATArarelLAKVGLAGKETSYPRRLSGGQQQRVAIARA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 155 IAKRPAVLLCDEPTGALDSKtgirVIEALLGVNRQLGT---TTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:PRK11264 159 LAMRPEVILFDEPTSALDPE----LVGEVLNTIRQLAQekrTMVIVTHEMSFaRDVADRAIFMDQGRI 222
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
9-218 |
1.74e-47 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 156.71 E-value: 1.74e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEvkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD--LDLT-ELEDRELTKYR 85
Cdd:COG4161 6 KNINCFYGSHQ----ALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGhqFDFSqKPSEKAIRLLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 RDhVGFVFQFYNLVPSLTAYENV--------ALVTEVAKSpmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAK 157
Cdd:COG4161 82 QK-VGMVFQQYNLWPHLTVMENLieapckvlGLSKEQARE--KAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMM 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 158 RPAVLLCDEPTGALDSKTGIRVIEALLGVNrQLGTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:COG4161 159 EPQVLLFDEPTAALDPEITAQVVEIIRELS-QTGITQVIVTHEVEFaRKVASQVVYMEKGRI 219
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
40-225 |
2.64e-47 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 158.81 E-value: 2.64e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 40 LLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELedrelTKYRRdHVGFVFQFYNLVPSLTAYENVALVTEVAKSPM 119
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNV-----PPHLR-HINMVFQSYALFPHMTVEENVAFGLKMRKVPR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 120 -----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTT 194
Cdd:TIGR01187 75 aeikpRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQLGITF 154
|
170 180 190
....*....|....*....|....*....|..
gi 1869873813 195 VIITHNAS-IQGVADRVLFFADGRIARVRTNE 225
Cdd:TIGR01187 155 VFVTHDQEeAMTMSDRIAIMRKGKIAQIGTPE 186
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
11-223 |
7.22e-47 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 157.17 E-value: 7.22e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEVkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyRRdHVG 90
Cdd:COG1125 7 VTKRYPDGTV---AVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDGEDIRDLDPVEL---RR-RIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKSPMRPADA-----LALVGL--EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:COG1125 80 YVIQQIGLFPHMTVAENIATVPRLLGWDKERIRArvdelLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPPILL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNasIQ---GVADRVLFFADGRIARVRT 223
Cdd:COG1125 160 MDEPFGALDPITREQLQDELLRLQRELGKTIVFVTHD--IDealKLGDRIAVMREGRIVQYDT 220
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-218 |
8.21e-47 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 161.99 E-value: 8.21e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVSGEVkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGGLDRP--TSGSLFFRDLDLTELEDR 79
Cdd:COG1123 2 TPLLEVRDLSVRYPGGDV--PAVDGVSLTIAPGETVALVGESGSGKSTLALaLMGLLPHGgrISGEVLLDGRDLLELSEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 EltkyRRDHVGFVFQ--FYNLVPsLTAYENVALVTEVAKSPMRPA-----DALALVGLEERMHHFPAQLSGGEQQRVAIA 152
Cdd:COG1123 80 L----RGRRIGMVFQdpMTQLNP-VTVGDQIAEALENLGLSRAEArarvlELLEAVGLERRLDRYPHQLSGGQRQRVAIA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 153 RAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG1123 155 MALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDlGVVAEIADRVVVMDDGRI 221
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
3-217 |
1.99e-46 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 153.74 E-value: 1.99e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYV---SGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD----LDLTE 75
Cdd:COG4778 2 TTLLEVENLSKTFTlhlQGGKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHdggwVDLAQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 76 LEDRELTKYRRDHVGFVFQFYNLVPSLTAYENVA-----LVTEVAKSPMRPADALALVGLEERMHH-FPAQLSGGEQQRV 149
Cdd:COG4778 82 ASPREILALRRRTIGYVSQFLRVIPRVSALDVVAeplleRGVDREEARARARELLARLNLPERLWDlPPATFSGGEQQRV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 150 AIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:COG4778 162 NIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEvREAVADRVVDVTPFS 229
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
29-219 |
2.61e-46 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 153.37 E-value: 2.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 29 DLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreltKYRRDhVGFVFQFYNLVPSLTAYENV 108
Cdd:COG3840 19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALP-----PAERP-VSMLFQENNLFPHLTVAQNI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 109 AL-------VTEVAKSpmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARA-IAKRPaVLLCDEPTGALDSktGIR-- 178
Cdd:COG3840 93 GLglrpglkLTAEQRA--QVEQALERVGLAGLLDRLPGQLSGGQRQRVALARClVRKRP-ILLLDEPFSALDP--ALRqe 167
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1869873813 179 VIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIA 219
Cdd:COG3840 168 MLDLVDELCRERGLTVLMVTHDpEDAARIADRVLLVADGRIA 209
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
16-219 |
9.99e-46 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 151.68 E-value: 9.99e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 16 VSGEVKVHALNeVDLEITEkEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQF 95
Cdd:cd03297 6 IEKRLPDFTLK-IDFDLNE-EVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDSRKKINLPPQQRKIGLVFQQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLVPSLTAYENVALVTEVaKSPM----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:cd03297 84 YALFPHLNVRENLAFGLKR-KRNRedriSVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSAL 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 172 DSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:cd03297 163 DRALRLQLLPELKQIKKNLNIPVIFVTHDLSeAEYLADRIVVMEDGRLQ 211
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
7-221 |
1.01e-45 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 153.09 E-value: 1.01e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldltELEDRELTKYRR 86
Cdd:COG4525 5 TVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEI--------TLDGVPVTGPGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHvGFVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:COG4525 77 DR-GVVFQKDALLPWLNVLDNVAFGLRLRGVPKaerraRAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRF 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHnaSIqgvaDRVLFFAD---------GRIARV 221
Cdd:COG4525 156 LLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITH--SV----EEALFLATrlvvmspgpGRIVER 218
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
24-218 |
2.63e-45 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 151.32 E-value: 2.63e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD--LDL-TELEDRELTKYRRDhVGFVFQFYNLVP 100
Cdd:PRK11124 17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGnhFDFsKTPSDKAIRELRRN-VGMVFQQYNLWP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENV--------ALVTEVAKSpmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:PRK11124 96 HLTVQQNLieapcrvlGLSKDQALA--RAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALD 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 173 SKTGIRVIEALLGVnRQLGTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:PRK11124 174 PEITAQIVSIIREL-AETGITQVIVTHEVEVaRKTASRVVYMENGHI 219
|
|
| tungstate_WtpC |
NF040840 |
tungstate ABC transporter ATP-binding protein WtpC; |
16-232 |
3.45e-45 |
|
tungstate ABC transporter ATP-binding protein WtpC;
Pssm-ID: 468779 [Multi-domain] Cd Length: 347 Bit Score: 154.08 E-value: 3.45e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 16 VSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEL--EDRELtkyrrdhvGFVF 93
Cdd:NF040840 7 LSKDWKEFKLRDISLEVKEGEYFIILGPSGAGKTVLLELIAGIWPPDSGKIYLDGKDITNLppEKRGI--------AYVY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 94 QFYNLVPSLTAYENVALVTEVAKSPM----RPADALA-LVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:NF040840 79 QNYMLFPHKTVFENIAFGLKLRKVPKeeieRKVKEIMeLLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLGTTTVIITHN--ASIQgVADRVLFFADGRIARV-RTNEV-RREAAE 232
Cdd:NF040840 159 SALDVQTRDELIREMKRWHREFGFTAIHVTHNfeEALS-LADRVGIMLNGRLSQVgDVREVfRRPKNE 225
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
25-215 |
7.39e-45 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 149.92 E-value: 7.39e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdldlteLEDRELTKYRRDHVgFVFQFYNLVPSLTA 104
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVI--------LEGKQITEPGPDRM-VVFQNYSLLPWLTV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEVAKSPMRPA-------DALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:TIGR01184 72 RENIALAVDRVLPDLSKSerraiveEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151
|
170 180 190
....*....|....*....|....*....|....*...
gi 1869873813 178 RVIEALLGVNRQLGTTTVIITHNasiqgvADRVLFFAD 215
Cdd:TIGR01184 152 NLQEELMQIWEEHRVTVLMVTHD------VDEALLLSD 183
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
5-219 |
8.83e-45 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 150.19 E-value: 8.83e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 5 VFSAKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKy 84
Cdd:COG1120 1 MLEAENLSVGY--GGRPV--LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELAR- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 85 rrdHVGFVFQFYNLVPSLTAYENVALvtevAKSPMRP-------------ADALALVGLEERMHHFPAQLSGGEQQRVAI 151
Cdd:COG1120 76 ---RIAYVPQEPPAPFGLTVRELVAL----GRYPHLGlfgrpsaedreavEEALERTGLEHLADRPVDELSGGERQRVLI 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 152 ARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITH--NASIQgVADRVLFFADGRIA 219
Cdd:COG1120 149 ARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHdlNLAAR-YADRLVLLKDGRIV 217
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
9-217 |
1.44e-44 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 147.14 E-value: 1.44e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDH 88
Cdd:cd03228 4 KNVSFSYPGRPKPV--LKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESL----RKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVpSLTAYENValvtevakspmrpadalalvgleermhhfpaqLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:cd03228 78 IAYVPQDPFLF-SGTIRENI--------------------------------LSGGQRQRIAIARALLRDPPILILDEAT 124
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 169 GALDSKTGIRVIEALLgvNRQLGTTTVIITHNASIQGVADRVLFFADGR 217
Cdd:cd03228 125 SALDPETEALILEALR--ALAKGKTVIVIAHRLSTIRDADRIIVLDDGR 171
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
25-168 |
2.36e-44 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 145.87 E-value: 2.36e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNLVPSLTA 104
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSL----RKEIGYVFQDPQLFPRLTV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 105 YENVALVTEV-----AKSPMRPADALALVGLE----ERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:pfam00005 77 RENLRLGLLLkglskREKDARAEEALEKLGLGdladRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
7-218 |
5.29e-44 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 148.41 E-value: 5.29e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFF----------RDLDLTEL 76
Cdd:COG4598 10 EVRDLHKSFGDLEV----LKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVggeeirlkpdRDGELVPA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 77 EDRELTKYRRdHVGFVFQFYNLVPSLTAYENVALV-TEVAKSPMRPADA-----LALVGLEERMHHFPAQLSGGEQQRVA 150
Cdd:COG4598 86 DRRQLQRIRT-RLGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAEAIEraealLAKVGLADKRDAYPAHLSGGQQQRAA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 151 IARAIAKRPAVLLCDEPTGALDSKtgiRVIEaLLGVNRQL---GTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:COG4598 165 IARALAMEPEVMLFDEPTSALDPE---LVGE-VLKVMRDLaeeGRTMLVVTHEMGFaRDVSSHVVFLHQGRI 232
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
7-218 |
6.99e-44 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 145.23 E-value: 6.99e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYvsGevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeledRELTKYRR 86
Cdd:cd03230 2 EVRNLSKRY--G--KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIK----KEPEEVKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dHVGFVFQFYNLVPSLTAYENValvtevakspmrpadalalvgleermhhfpaQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:cd03230 74 -RIGYLPEEPSLYENLTVRENL-------------------------------KLSGGMKQRLALAQALLHDPELLILDE 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNRQlGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:cd03230 122 PTSGLDPESRREFWELLRELKKE-GKTILLSSHIlEEAERLCDRVAILNNGRI 173
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
25-225 |
1.03e-43 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 147.10 E-value: 1.03e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltkyRRDhVGFVFQFYNLVPSLTA 104
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPE-----KRD-ISYVPQNYALFPHMTV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVA-----LVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRV 179
Cdd:cd03299 89 YKNIAyglkkRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 180 IEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARVRTNE 225
Cdd:cd03299 169 REELKKIRKEFGVTVLHVTHDfEEAWALADKVAIMLNGKLIQVGKPE 215
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
22-225 |
2.14e-43 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 146.04 E-value: 2.14e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRrdhVGFVFQFYNLVPS 101
Cdd:cd03219 13 LVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLG---IGRTFQIPRLFPE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVAL---------------VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:cd03219 90 LTVLENVMVaaqartgsglllaraRREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDE 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNRQlGTTTVIITHN-ASIQGVADRVLFF------ADGRIARVRTNE 225
Cdd:cd03219 170 PAAGLNPEETEELAELIRELRER-GITVLLVEHDmDVVMSLADRVTVLdqgrviAEGTPDEVRNNP 234
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
4-199 |
3.91e-43 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 144.54 E-value: 3.91e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 4 AVFSAKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltk 83
Cdd:COG4133 1 MMLEAENLSCRR--GERLL--FSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARED---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 84 yRRDHVGFVFQFYNLVPSLTAYENVALVTE---VAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:COG4133 73 -YRRRLAYLGHADGLKPELTVRENLRFWAAlygLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAP 151
|
170 180 190
....*....|....*....|....*....|....*....
gi 1869873813 161 VLLCDEPTGALDsKTGIRVIEALLGVNRQLGTTTVIITH 199
Cdd:COG4133 152 LWLLDEPFTALD-AAGVALLAELIAAHLARGGAVLLTTH 189
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
11-219 |
8.46e-43 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 145.65 E-value: 8.46e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeleDRELTKYRRDHVG 90
Cdd:TIGR04520 6 VSFSYPESEKP--ALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTL---DEENLWEIRKKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQfyN----LVpSLTAYENVALVTE---VAKSPMRP--ADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:TIGR04520 81 MVFQ--NpdnqFV-GATVEDDVAFGLEnlgVPREEMRKrvDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDI 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIA 219
Cdd:TIGR04520 158 IILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVLADRVIVMNKGKIV 215
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
8-229 |
1.62e-42 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 144.23 E-value: 1.62e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVsgevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltkyRRD 87
Cdd:COG4555 4 VENLSKKYG----KVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPRE-----ARR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 HVGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVL 162
Cdd:COG4555 75 QIGVLPDERGLYDRLTVRENIRYFAELYGLFdeelkKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVL 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 163 LCDEPTGALD--SKTGIR-VIEALlgvnRQLGTTTVIITHNAS-IQGVADRVLFFADGRIARVRTNEVRRE 229
Cdd:COG4555 155 LLDEPTNGLDvmARRLLReILRAL----KKEGKTVLFSSHIMQeVEALCDRVVILHKGKVVAQGSLDELRE 221
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
2-230 |
4.13e-42 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 143.26 E-value: 4.13e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 2 SEAVFSAKALTKTYvsGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDrel 81
Cdd:COG0411 1 SDPLLEVRGLTKRF--GGLV--AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPP--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 82 tkYRRDHVGFV--FQFYNLVPSLTAYENVAL----------VTEVAKSPMRPA----------DALALVGLEERMHHFPA 139
Cdd:COG0411 74 --HRIARLGIArtFQNPRLFPELTVLENVLVaaharlgrglLAALLRLPRARReereareraeELLERVGLADRADEPAG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 140 QLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADR--VLFF--- 213
Cdd:COG0411 152 NLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDlVMGLADRivVLDFgrv 231
|
250
....*....|....*...
gi 1869873813 214 -ADGRIARVRTNEVRREA 230
Cdd:COG0411 232 iAEGTPAEVRADPRVIEA 249
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
21-217 |
5.72e-42 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 140.07 E-value: 5.72e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQfynlvp 100
Cdd:cd00267 11 GRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEEL----RRRIGYVPQ------ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 sltayenvalvtevakspmrpadalalvgleermhhfpaqLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVI 180
Cdd:cd00267 81 ----------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLL 120
|
170 180 190
....*....|....*....|....*....|....*...
gi 1869873813 181 EALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:cd00267 121 ELLRELAEE-GRTVIIVTHDPElAELAADRVIVLKDGK 157
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
27-220 |
7.38e-42 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 145.63 E-value: 7.38e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDldlTELEDRE----LTKYRRdHVGFVFQFYNLVPSL 102
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGG---EVLQDSArgifLPPHRR-RIGYVFQEARLFPHL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYENVALV---TEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRV 179
Cdd:COG4148 93 SVRGNLLYGrkrAPRAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEI 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 180 IEALLGVNRQLGTTTVIITHnaSIQGV---ADRVLFFADGRIAR 220
Cdd:COG4148 173 LPYLERLRDELDIPILYVSH--SLDEVarlADHVVLLEQGRVVA 214
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
24-219 |
8.40e-42 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 150.75 E-value: 8.40e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ----FYNlv 99
Cdd:COG2274 490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASL----RRQIGVVLQdvflFSG-- 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 pslTAYENVALVTEVAkSPMRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:COG2274 564 ---TIRENITLGDPDA-TDEEIIEAARLAGLHDFIEALPmgydtvvgeggSNLSGGQRQRLAIARALLRNPRILILDEAT 639
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 169 GALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRIA 219
Cdd:COG2274 640 SALDAETEAIILENLRRLLK--GRTVIIIAHRLSTIRLADRIIVLDKGRIV 688
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
9-218 |
1.28e-41 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 142.12 E-value: 1.28e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELedreltkyrRDH 88
Cdd:PRK11247 16 NAVSKRYGERTV----LNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEA---------RED 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTevaKSPMRPA--DALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:PRK11247 83 TRLMFQDARLLPWKKVIDNVGLGL---KGQWRDAalQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDE 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:PRK11247 160 PLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSeAVAMADRVLLIEEGKI 212
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
11-218 |
1.54e-41 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 141.17 E-value: 1.54e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEvkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdHVG 90
Cdd:PRK10908 7 VSKAYLGGR---QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRR-QIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:PRK10908 83 MIFQDHHLLMDRTVYDNVAIPLIIAGASgddirRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLAD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 166 EPTGALDSKTGIRVIEALLGVNRqLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:PRK10908 163 EPTGNLDDALSEGILRLFEEFNR-VGVTVLMATHDIGlISRRSYRMLTLSDGHL 215
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
1-210 |
1.86e-41 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 143.72 E-value: 1.86e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTY-VSGEV------KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDL 73
Cdd:COG4608 3 MAEPLLEVRDLKKHFpVRGGLfgrtvgVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 74 TELEDRELTKYRRDhVGFVFQ--FYNLVPSLTAYENVALVTEV-----AKSPM-RPADALALVGL-EERMHHFPAQLSGG 144
Cdd:COG4608 83 TGLSGRELRPLRRR-MQMVFQdpYASLNPRMTVGDIIAEPLRIhglasKAERReRVAELLELVGLrPEHADRYPHEFSGG 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 145 EQQRVAIARAIAKRPAVLLCDEPTGALD-SktgIR--VIEALLGVNRQLGTTTVIITHNAS-IQGVADRV 210
Cdd:COG4608 162 QRQRIGIARALALNPKLIVCDEPVSALDvS---IQaqVLNLLEDLQDELGLTYLFISHDLSvVRHISDRV 228
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
5-218 |
6.05e-41 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 140.12 E-value: 6.05e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 5 VFSAKALTKTYVsgevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLL---NIMGGL--DRPTSGSLFFRDLDLTElEDR 79
Cdd:TIGR00972 1 AIEIENLNLFYG----EKEALKNINLDIPKNQVTALIGPSGCGKSTLLrslNRMNDLvpGVRIEGKVLFDGQDIYD-KKI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELTKYRRdHVGFVFQFYNLVPsLTAYENVAL------------VTEVAKSPMRPAdalAL-VGLEERMHHFPAQLSGGEQ 146
Cdd:TIGR00972 76 DVVELRR-RVGMVFQKPNPFP-MSIYDNIAYgprlhgikdkkeLDEIVEESLKKA---ALwDEVKDRLHDSALGLSGGQQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 147 QRVAIARAIAKRPAVLLCDEPTGALDSKTGIRvIEALLgvnRQLGT--TTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:TIGR00972 151 QRLCIARALAVEPEVLLLDEPTSALDPIATGK-IEELI---QELKKkyTIVIVTHNmQQAARISDRTAFFYDGEL 221
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-231 |
6.76e-41 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 139.84 E-value: 6.76e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEledre 80
Cdd:COG1121 2 MMMPAIELENLTVSY--GGRPV--LEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRR----- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 ltkyRRDHVGFVFQFYNLVPS--LTAYENVALVTEVAKSPMRP---------ADALALVGLEERMHHFPAQLSGGEQQRV 149
Cdd:COG1121 73 ----ARRRIGYVPQRAEVDWDfpITVRDVVLMGRYGRRGLFRRpsradreavDEALERVGLEDLADRPIGELSGGQQQRV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 150 AIARAIAKRPAVLLCDEPTGALDSKTgIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARVRTNEVRR 228
Cdd:COG1121 149 LLARALAQDPDLLLLDEPFAGVDAAT-EEALYELLRELRREGKTILVVTHDlGAVREYFDRVLLLNRGLVAHGPPEEVLT 227
|
...
gi 1869873813 229 EAA 231
Cdd:COG1121 228 PEN 230
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
7-220 |
6.44e-40 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 136.55 E-value: 6.44e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGevkvHALNEVDLEITEKeVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDreltKYRR 86
Cdd:cd03264 2 QLENLTKRYGKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQ----KLRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dHVGFVFQFYNLVPSLTAYENV---ALVTEVAKS--PMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:cd03264 73 -RIGYLPQEFGVYPNFTVREFLdyiAWLKGIPSKevKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALlgvnRQLGTTTVII--THNAS-IQGVADRVLFFADGRIAR 220
Cdd:cd03264 152 LIVDEPTAGLDPEERIRFRNLL----SELGEDRIVIlsTHIVEdVESLCNQVAVLNKGKLVF 209
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
24-219 |
7.73e-40 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 144.15 E-value: 7.73e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ----Fynlv 99
Cdd:COG1132 355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESL----RRQIGVVPQdtflF---- 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 pSLTAYENVAL----VT--EVAkspmrpaDALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVL 162
Cdd:COG1132 427 -SGTIRENIRYgrpdATdeEVE-------EAAKAAQAHEFIEALPdgydtvvgergVNLSGGQRQRIAIARALLKDPPIL 498
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 163 LCDEPTGALDSKTGIRVIEALLGVNRqlGTTTVIITHN-ASIQGvADRVLFFADGRIA 219
Cdd:COG1132 499 ILDEATSALDTETEALIQEALERLMK--GRTTIVIAHRlSTIRN-ADRILVLDDGRIV 553
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
29-219 |
1.10e-39 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 136.08 E-value: 1.10e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 29 DLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELE--DREltkyrrdhVGFVFQFYNLVPSLTAYE 106
Cdd:cd03298 18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPpaDRP--------VSMLFQENNLFAHLTVEQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 107 NVALvtevAKSP---MRPAD------ALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:cd03298 90 NVGL----GLSPglkLTAEDrqaievALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRA 165
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1869873813 178 RVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:cd03298 166 EMLDLVLDLHAETKMTVLMVTHQPEdAKRLAQRVVFLDNGRIA 208
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
21-219 |
1.63e-39 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 135.64 E-value: 1.63e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTkyrRDHVGFVFQFYNLVP 100
Cdd:cd03224 12 KSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERA---RAGIGYVPEGRRIFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVALVTEV---AKSPMRPADALALV-GLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTG 176
Cdd:cd03224 89 ELTVEENLLLGAYArrrAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIV 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 177 IRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:cd03224 169 EEIFEAIRELRDE-GVTILLVEQNARfALEIADRAYVLERGRVV 211
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
11-200 |
2.25e-38 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 136.89 E-value: 2.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYvSGEvkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELedrelTKYRRDhVG 90
Cdd:PRK11607 25 LTKSF-DGQ---HAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHV-----PPYQRP-IN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:PRK11607 95 MMFQSYALFPHMTVEQNIAFGLKQDKLPkaeiaSRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLD 174
|
170 180 190
....*....|....*....|....*....|....*
gi 1869873813 166 EPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN 200
Cdd:PRK11607 175 EPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHD 209
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
7-218 |
2.28e-38 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 131.40 E-value: 2.28e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKyrr 86
Cdd:cd03214 1 EVENLSVGYGGRTV----LDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELAR--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dHVGFVFQfynlvpsltayenvalvtevakspmrpadALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:cd03214 74 -KIAYVPQ-----------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDE 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN---ASIqgVADRVLFFADGRI 218
Cdd:cd03214 124 PTSHLDIAHQIELLELLRRLARERGKTVVMVLHDlnlAAR--YADRVILLKDGRI 176
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
7-223 |
3.14e-38 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 139.51 E-value: 3.14e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrR 86
Cdd:COG4988 338 ELEDVSFSYPGGRP---ALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASW----R 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQFyNLVPSLTAYENVALVTEVAkSPMRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAI 155
Cdd:COG4988 411 RQIAWVPQN-PYLFAGTIRENLRLGRPDA-SDEELEAALEAAGLDEFVAALPdgldtplgeggRGLSGGQAQRLALARAL 488
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 156 AKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRIARVRT 223
Cdd:COG4988 489 LRDAPLLLLDEPTAHLDAETEAEILQALRRLAK--GRTVILITHRLALLAQADRILVLDDGRIVEQGT 554
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
11-218 |
3.54e-38 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 132.24 E-value: 3.54e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYvsGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLteLEDReltKYRRDHVG 90
Cdd:cd03263 6 LTKTY--KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSI--RTDR---KAARQSLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKSPMRPADALAL-----VGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:cd03263 79 YCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVElllrvLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 166 EPTGALDSKTGIRVIEALLGVnrQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:cd03263 159 EPTSGLDPASRRAIWDLILEV--RKGRSIILTTHSMDeAEALCDRIAIMSDGKL 210
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
9-218 |
4.13e-38 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 135.62 E-value: 4.13e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeleDRELTKyrRDh 88
Cdd:PRK11432 10 KNITKRFGSNTV----IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT---HRSIQQ--RD- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVAL---VTEVAKSPM--RPADALALV---GLEERmhhFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:PRK11432 80 ICMVFQSYALFPHMSLGENVGYglkMLGVPKEERkqRVKEALELVdlaGFEDR---YVDQISGGQQQRVALARALILKPK 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 161 VLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQ-GVADRVLFFADGRI 218
Cdd:PRK11432 157 VLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAfAVSDTVIVMNKGKI 215
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
23-218 |
1.76e-37 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 131.31 E-value: 1.76e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLL---NIMggLDR-P---TSGSLFFRDLDLTElEDRELTKYRRdHVGFVFQF 95
Cdd:COG1117 25 QALKDINLDIPENKVTALIGPSGCGKSTLLrclNRM--NDLiPgarVEGEILLDGEDIYD-PDVDVVELRR-RVGMVFQK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLVPsLTAYENVA----LVTEVAKSPM--RPADALALVGL-EE---RMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:COG1117 101 PNPFP-KSIYDNVAyglrLHGIKSKSELdeIVEESLRKAALwDEvkdRLKKSALGLSGGQQQRLCIARALAVEPEVLLMD 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 166 EPTGALDSKTGIRvIEALLgvnRQLGT--TTVIITHN---ASiqGVADRVLFFADGRI 218
Cdd:COG1117 180 EPTSALDPISTAK-IEELI---LELKKdyTIVIVTHNmqqAA--RVSDYTAFFYLGEL 231
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
9-199 |
7.38e-37 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 132.27 E-value: 7.38e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsgEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkyrRDh 88
Cdd:PRK11650 7 QAVRKSY---DGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPAD-----RD- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:PRK11650 78 IAMVFQNYALYPHMSVRENMAYGLKIRGMPkaeieERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAVFL 157
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1869873813 164 CDEPTGALDSKtgIRV-----IEALlgvNRQLGTTTVIITH 199
Cdd:PRK11650 158 FDEPLSNLDAK--LRVqmrleIQRL---HRRLKTTSLYVTH 193
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
21-218 |
7.76e-37 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 128.86 E-value: 7.76e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ----FY 96
Cdd:cd03245 16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADL----RRNIGYVPQdvtlFY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 97 NlvpslTAYENVALVTEVAKSPmRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:cd03245 92 G-----TLRDNITLGAPLADDE-RILRAAELAGVTDFVNKHPngldlqigergRGLSGGQRQAVALARALLNDPPILLLD 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 166 EPTGALDSKTGIRVIEALlgvnRQL--GTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:cd03245 166 EPTSAMDMNSEERLKERL----RQLlgDKTLIIITHRPSLLDLVDRIIVMDSGRI 216
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
24-225 |
1.76e-36 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 134.89 E-value: 1.76e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ----FYNlv 99
Cdd:COG4987 350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDL----RRRIAVVPQrphlFDT-- 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 pslTAYENVALVTEVAkSPMRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:COG4987 424 ---TLRENLRLARPDA-TDEELWAALERVGLGDWLAALPdgldtwlgeggRRLSGGERRRLALARALLRDAPILLLDEPT 499
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 169 GALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRIARVRTNE 225
Cdd:COG4987 500 EGLDAATEQALLADLLEALA--GRTVLLITHRLAGLERMDRILVLEDGRIVEQGTHE 554
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-228 |
2.46e-36 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 134.04 E-value: 2.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKT-TLLNIMGGLDRP---TSGSLFFRDLDLTEL 76
Cdd:COG4172 2 MSMPLLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILRLLPDPaahPSGSILFDGQDLLGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 77 EDRELTKYRRDHVGFVFQ--FYNLVPSLTAYENVALVTEVaKSPMRPADA-------LALVGL---EERMHHFPAQLSGG 144
Cdd:COG4172 82 SERELRRIRGNRIAMIFQepMTSLNPLHTIGKQIAEVLRL-HRGLSGAAAraralelLERVGIpdpERRLDAYPHQLSGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 145 EQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVLFFADGRIarVRT 223
Cdd:COG4172 161 QRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVvRRFADRVAVMRQGEI--VEQ 238
|
....*
gi 1869873813 224 NEVRR 228
Cdd:COG4172 239 GPTAE 243
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
21-219 |
7.47e-36 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 126.64 E-value: 7.47e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGgLDRPTSGSLFFRDLDLTELEDRELTkyrRDHVGFVFQFYNLV 99
Cdd:COG0410 15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKaISG-LLPPRSGSIRFDGEDITGLPPHRIA---RLGIGYVPEGRRIF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 PSLTAYENVALVTEVAKSPMRPADALALVG-----LEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTgaldsk 174
Cdd:COG0410 91 PSLTVEENLLLGAYARRDRAEVRADLERVYelfprLKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPS------ 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 175 TGI------RVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:COG0410 165 LGLapliveEIFEIIRRLNRE-GVTILLVEQNARfALEIADRAYVLERGRIV 215
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
23-211 |
3.82e-35 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 124.18 E-value: 3.82e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEledreltkyRRDHVGFVFQFYNLVPS- 101
Cdd:cd03235 13 PVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEK---------ERKRIGYVPQRRSIDRDf 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 -LTAYENVALVTEVAKSPMRPAD---------ALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:cd03235 84 pISVRDVVLMGLYGHKGLFRRLSkadkakvdeALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGV 163
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1869873813 172 DSKTGIRVIEALLGVNRQlGTTTVIITHN-ASIQGVADRVL 211
Cdd:cd03235 164 DPKTQEDIYELLRELRRE-GMTILVVTHDlGLVLEYFDRVL 203
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
22-218 |
1.21e-34 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 129.42 E-value: 1.21e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTL-LNIMGGLdrPTSGSLFFRDLDLTELEDRELTKYRRdHVGFVFQ--FYNL 98
Cdd:COG4172 299 VKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLI--PSEGEIRFDGQDLDGLSRRALRPLRR-RMQVVFQdpFGSL 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLTAYENVA---LVTEVAKSP----MRPADALALVGL-EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGA 170
Cdd:COG4172 376 SPRMTVGQIIAeglRVHGPGLSAaerrARVAEALEEVGLdPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSA 455
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 171 LDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG4172 456 LDVSVQAQILDLLRDLQREHGLAYLFISHDlAVVRALAHRVMVMKDGKV 504
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
24-200 |
2.31e-34 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 123.27 E-value: 2.31e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldltELEDRELTKYRRDHvGFVFQFYNLVPSLT 103
Cdd:PRK11248 16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSI--------TLDGKPVEGPGAER-GVVFQNEGLLPWRN 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIR 178
Cdd:PRK11248 87 VQDNVAFGLQLAGVEkmqrlEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQ 166
|
170 180
....*....|....*....|..
gi 1869873813 179 VIEALLGVNRQLGTTTVIITHN 200
Cdd:PRK11248 167 MQTLLLKLWQETGKQVLLITHD 188
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
7-223 |
3.56e-34 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 123.26 E-value: 3.56e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVS-GEVKVHA----LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREL 81
Cdd:PRK10419 5 NVSGLSHHYAHgGLSGKHQhqtvLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 82 TKYRRDhVGFVFQfynlvPSLTAYENVALVTEVAKSPMR------PADALA-------LVGL-EERMHHFPAQLSGGEQQ 147
Cdd:PRK10419 85 KAFRRD-IQMVFQ-----DSISAVNPRKTVREIIREPLRhllsldKAERLArasemlrAVDLdDSVLDKRPPQLSGGQLQ 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 148 RVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIARVRT 223
Cdd:PRK10419 159 RVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRlVERFCQRVMVMDNGQIVETQP 235
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
27-219 |
1.25e-33 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 123.68 E-value: 1.25e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQFYNLVPSLTAYE 106
Cdd:TIGR02142 15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFLPPEKRRIGYVFQEARLFPHLSVRG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 107 NVAL---VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEAL 183
Cdd:TIGR02142 95 NLRYgmkRARPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYL 174
|
170 180 190
....*....|....*....|....*....|....*..
gi 1869873813 184 LGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:TIGR02142 175 ERLHAEFGIPILYVSHSLQeVLRLADRVVVLEDGRVA 211
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
2-229 |
1.84e-33 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 125.52 E-value: 1.84e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 2 SEAVFSAKALTKTYvSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDldltelEDREL 81
Cdd:COG1129 1 AEPLLEMRGISKSF-GG---VKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDG------EPVRF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 82 TKYR--RDH-VGFVFQFYNLVPSLTAYENVALVTEVAKSPM--------RPADALALVGLEERMHHFPAQLSGGEQQRVA 150
Cdd:COG1129 71 RSPRdaQAAgIAIIHQELNLVPNLSVAENIFLGREPRRGGLidwramrrRARELLARLGLDIDPDTPVGDLSVAQQQLVE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 151 IARAIAKRPAVLLCDEPTGALDSKTgirvIEALLGVNRQL---GTTTVIITHN-ASIQGVADRVLFFADGR-IARVRTNE 225
Cdd:COG1129 151 IARALSRDARVLILDEPTASLTERE----VERLFRIIRRLkaqGVAIIYISHRlDEVFEIADRVTVLRDGRlVGTGPVAE 226
|
....
gi 1869873813 226 VRRE 229
Cdd:COG1129 227 LTED 230
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
3-234 |
2.23e-33 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 125.69 E-value: 2.23e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVS---GEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD----LDLTE 75
Cdd:TIGR03269 277 EPIIKVRNVSKRYISvdrGVVK--AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVgdewVDMTK 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 76 LEDRELTKYRRdHVGFVFQFYNLVPSLTAYENVA------LVTEVAKspMRPADALALVGLEER-----MHHFPAQLSGG 144
Cdd:TIGR03269 355 PGPDGRGRAKR-YIGILHQEYDLYPHRTVLDNLTeaigleLPDELAR--MKAVITLKMVGFDEEkaeeiLDKYPDELSEG 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 145 EQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIarVRT 223
Cdd:TIGR03269 432 ERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDfVLDVCDRAALMRDGKI--VKI 509
|
250
....*....|.
gi 1869873813 224 NEVRREAAELT 234
Cdd:TIGR03269 510 GDPEEIVEELT 520
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
9-218 |
2.93e-33 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 119.24 E-value: 2.93e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVsgevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDreltkyRRDH 88
Cdd:cd03268 4 NDLTKTYG----KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIE------ALRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENV---ALVTEVAKSpmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:cd03268 74 IGALIEAPGFYPNLTARENLrllARLLGIRKK--RIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILD 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 166 EPTGALDSKtGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:cd03268 152 EPTNGLDPD-GIKELRELILSLRDQGITVLISSHLLSeIQKVADRIGIINKGKL 204
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
19-218 |
4.36e-33 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 119.57 E-value: 4.36e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 19 EVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNImggLDR---PTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ- 94
Cdd:cd03249 15 DVPI--LKGLSLTIPPGKTVALVGSSGCGKSTVVSL---LERfydPTSGEILLDGVDIRDLNLRWL----RSQIGLVSQe 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 95 ---FYNlvpslTAYENVAL-----VTEVAKSPMRPADALALV-----GLEERMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:cd03249 86 pvlFDG-----TIAENIRYgkpdaTDEEVEEAAKKANIHDFImslpdGYDTLVGERGSQLSGGQKQRIAIARALLRNPKI 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALlgVNRQLGTTTVIITHN-ASIQGvADRVLFFADGRI 218
Cdd:cd03249 161 LLLDEATSALDAESEKLVQEAL--DRAMKGRTTIVIAHRlSTIRN-ADLIAVLQNGQV 215
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
9-221 |
6.55e-33 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 122.06 E-value: 6.55e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsGEVKVHalNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELE--DREltkyrr 86
Cdd:PRK11000 7 RNVTKAY--GDVVIS--KDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPpaERG------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dhVGFVFQFYNLVPSLTAYENVAL--------VTEVAKSPMRPADALALVGLEERMhhfPAQLSGGEQQRVAIARAIAKR 158
Cdd:PRK11000 77 --VGMVFQSYALYPHLSVAENMSFglklagakKEEINQRVNQVAEVLQLAHLLDRK---PKALSGGQRQRVAIGRTLVAE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 159 PAVLLCDEPTGALDSktGIRV---IEaLLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARV 221
Cdd:PRK11000 152 PSVFLLDEPLSNLDA--ALRVqmrIE-ISRLHKRLGRTMIYVTHDqVEAMTLADKIVVLDAGRVAQV 215
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
8-225 |
9.11e-33 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 118.24 E-value: 9.11e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVSGEvkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeledRELTKYRRd 87
Cdd:cd03265 3 VENLVKKYGDFE----AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVV----REPREVRR- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 HVGFVFQFYNLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVL 162
Cdd:cd03265 74 RIGIVFQDLSVDDELTGWENLYIHARLYGVPgaerrERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 163 LCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRIARVRTNE 225
Cdd:cd03265 154 FLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMeEAEQLCDRVAIIDHGRIIAEGTPE 217
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
3-199 |
9.15e-33 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 119.35 E-value: 9.15e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVSGEvkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGL---DRpTSGS---LFFRDLDLTEL 76
Cdd:PRK09984 2 QTIIRVEKLAKTFNQHQ----ALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDK-SAGShieLLGRTVQREGR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 77 EDRELTKyRRDHVGFVFQFYNLVPSLTAYENVaLVTEVAKSPM--------------RPADALALVGLEERMHHFPAQLS 142
Cdd:PRK09984 77 LARDIRK-SRANTGYIFQQFNLVNRLSVLENV-LIGALGSTPFwrtcfswftreqkqRALQALTRVGMVHFAHQRVSTLS 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 143 GGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITH 199
Cdd:PRK09984 155 GGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLH 211
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-216 |
1.15e-32 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 119.11 E-value: 1.15e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVsgevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLL---NIMGGL--DRPTSGSLFFRDLDLte 75
Cdd:PRK14239 1 MTEPILQVSDLSVYYN----KKKALNSVSLDFYPNEITALIGPSGSGKSTLLrsiNRMNDLnpEVTITGSIVYNGHNI-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 76 LEDRELTKYRRDHVGFVFQFYNLVPsLTAYENV------------ALVTEVAKSPMRPADALALVglEERMHHFPAQLSG 143
Cdd:PRK14239 75 YSPRTDTVDLRKEIGMVFQQPNPFP-MSIYENVvyglrlkgikdkQVLDEAVEKSLKGASIWDEV--KDRLHDSALGLSG 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 144 GEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLgtTTVIITHN---ASiqGVADRVLFFADG 216
Cdd:PRK14239 152 GQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDDY--TMLLVTRSmqqAS--RISDRTGFFLDG 223
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
29-219 |
1.97e-32 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 117.76 E-value: 1.97e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 29 DLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDldltelEDRELTKYRRDHVGFVFQFYNLVPSLTAYENV 108
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNG------QDHTTTPPSRRPVSMLFQENNLFSHLTVAQNI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 109 AL-------VTEVAKSPMRpaDALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIE 181
Cdd:PRK10771 93 GLglnpglkLNAAQREKLH--AIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLT 170
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1869873813 182 ALLGVNRQLGTTTVIITHN----ASIqgvADRVLFFADGRIA 219
Cdd:PRK10771 171 LVSQVCQERQLTLLMVSHSledaARI---APRSLVVADGRIA 209
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-218 |
2.30e-32 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 118.96 E-value: 2.30e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE 80
Cdd:PRK13635 1 MKEEIIRVEHISFRY--PDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LtkyrRDHVGFVFQFY-NLVPSLTAYENVALVTE---VAKSPM--RPADALALVGLEERMHHFPAQLSGGEQQRVAIARA 154
Cdd:PRK13635 79 V----RRQVGMVFQNPdNQFVGATVQDDVAFGLEnigVPREEMveRVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGV 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 155 IAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK13635 155 LALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQADRVIVMNKGEI 218
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
11-223 |
7.06e-32 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 120.14 E-value: 7.06e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEVKvhalnEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVG 90
Cdd:PRK10070 35 LEKTGLSLGVK-----DASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:PRK10070 110 MVFQSFALMPHMTVLDNTAFGMELAGINAeerreKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMD 189
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 166 EPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRIARVRT 223
Cdd:PRK10070 190 EAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLdEAMRIGDRIAIMQNGEVVQVGT 248
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
1-218 |
9.76e-32 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 116.61 E-value: 9.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLT------ 74
Cdd:PRK10619 1 MSENKLNVIDLHKRYGEHEV----LKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINlvrdkd 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 75 ---ELEDRELTKYRRDHVGFVFQFYNLVPSLTAYENV------ALVTEVAKSPMRPADALALVGLEERMH-HFPAQLSGG 144
Cdd:PRK10619 77 gqlKVADKNQLRLLRTRLTMVFQHFNLWSHMTVLENVmeapiqVLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGG 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 145 EQQRVAIARAIAKRPAVLLCDEPTGALDSKtgirVIEALLGVNRQL---GTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:PRK10619 157 QQQRVSIARALAMEPEVLLFDEPTSALDPE----LVGEVLRIMQQLaeeGKTMVVVTHEMGFaRHVSSHVIFLHQGKI 230
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
11-233 |
1.26e-31 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 117.07 E-value: 1.26e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSG---EVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTElEDRELTKYRRd 87
Cdd:PRK13637 8 LTHIYMEGtpfEKK--ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITD-KKVKLSDIRK- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 HVGFVFQF--YNLVPSlTAYENVA-----LVTEVAKSPMRPADALALVGL--EERMHHFPAQLSGGEQQRVAIARAIAKR 158
Cdd:PRK13637 84 KVGLVFQYpeYQLFEE-TIEKDIAfgpinLGLSEEEIENRVKRAMNIVGLdyEDYKDKSPFELSGGQKRRVAIAGVVAME 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 159 PAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIARVRT-NEVRREAAEL 233
Cdd:PRK13637 163 PKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEdVAKLADRIIVMNKGKCELQGTpREVFKEVETL 239
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
8-220 |
1.67e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 117.11 E-value: 1.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVSG---EVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSL--FFRD------LDLTEL 76
Cdd:PRK13651 5 VKNIVKIFNKKlptELK--ALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewIFKDeknkkkTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 77 EDREL----TKYR--------RDHVGFVFQF--YNLVPSLT----AYENVALVTEVAKSPMRPADALALVGL-EERMHHF 137
Cdd:PRK13651 83 VLEKLviqkTRFKkikkikeiRRRVGVVFQFaeYQLFEQTIekdiIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQRS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 138 PAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNA-SIQGVADRVLFFADG 216
Cdd:PRK13651 163 PFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQ-GKTIILVTHDLdNVLEWTKRTIFFKDG 241
|
....
gi 1869873813 217 RIAR 220
Cdd:PRK13651 242 KIIK 245
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
24-221 |
2.88e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 115.86 E-value: 2.88e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLteleDRELTKYRRDHVGFVFQFY-NLVPSL 102
Cdd:PRK13632 24 ALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITI----SKENLKEIRKKIGIIFQNPdNQFIGA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYENVALVTE---VAKSPMRP--ADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:PRK13632 100 TVEDDIAFGLEnkkVPPKKMKDiiDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNPEIIIFDESTSMLDPKGKR 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 178 RVIEALLGVnRQLGTTTVI-ITHNASIQGVADRVLFFADGRIARV 221
Cdd:PRK13632 180 EIKKIMVDL-RKTRKKTLIsITHDMDEAILADKVIVFSEGKLIAQ 223
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
6-229 |
4.53e-31 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 114.18 E-value: 4.53e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 6 FSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELedrELTKYR 85
Cdd:cd03218 1 LRAENLSKRYGKRKV----VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKL---PMHKRA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 RDHVGFVFQFYNLVPSLTAYENVALVTEVAKSP----MRPADA-LALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:cd03218 74 RLGIGYLPQEASIFRKLTVEENILAVLEIRGLSkkerEEKLEElLEEFHITHLRKSKASSLSGGERRRVEIARALATNPK 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 161 VLLCDEPTGALDSKTgIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADR--VLF----FADGRIARVRTNEVRRE 229
Cdd:cd03218 154 FLLLDEPFAGVDPIA-VQDIQKIIKILKDRGIGVLITDHNVReTLSITDRayIIYegkvLAEGTPEEIAANELVRK 228
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
6-219 |
6.23e-31 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 111.75 E-value: 6.23e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 6 FSAKALTKTYVSgevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRdldlteledreltkyr 85
Cdd:cd03216 1 LELRGITKRFGG----VKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVD---------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 rdhvGFVFQFYNlvpsltayenvalvtevakspmrPADALALvGLEerMHHfpaQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:cd03216 61 ----GKEVSFAS-----------------------PRDARRA-GIA--MVY---QLSVGERQMVEIARALARNARLLILD 107
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 166 EPTGALDSKTgirvIEALLGVNRQL---GTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:cd03216 108 EPTAALTPAE----VERLFKVIRRLraqGVAVIFISHRLDeVFEIADRVTVLRDGRVV 161
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
25-219 |
2.19e-30 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 112.36 E-value: 2.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRP---TSGSLFFRDldlteledRELTKYR-RDHVGFVFQFYNLVP 100
Cdd:cd03234 23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGggtTSGQILFNG--------QPRKPDQfQKCVAYVRQDDILLP 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVA---------LVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:cd03234 95 GLTVRETLTytailrlprKSSDAIRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 172 DSKTGIRVIEALlgvnRQLGTT--TVIIT-HN--ASIQGVADRVLFFADGRIA 219
Cdd:cd03234 175 DSFTALNLVSTL----SQLARRnrIVILTiHQprSDLFRLFDRILLLSSGEIV 223
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
2-218 |
3.03e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 113.26 E-value: 3.03e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 2 SEAVFSAKALTKTYVSGE--VKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDr 79
Cdd:PRK13633 1 MNEMIKCKNVSYKYESNEesTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEEN- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 elTKYRRDHVGFVFQFY-NLVPSLTAYENVALVTE---VAKSPMRPA--DALALVGLEERMHHFPAQLSGGEQQRVAIAR 153
Cdd:PRK13633 80 --LWDIRNKAGMVFQNPdNQIVATIVEEDVAFGPEnlgIPPEEIRERvdESLKKVGMYEYRRHAPHLLSGGQKQRVAIAG 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 154 AIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK13633 158 ILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVEADRIIVMDSGKV 222
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
15-218 |
5.48e-30 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 110.42 E-value: 5.48e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 15 YVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEledreltKYRRDHVGFV-- 92
Cdd:cd03226 6 SFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKA-------KERRKSIGYVmq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 93 ---FQFYnlvpSLTAYENVAL-VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:cd03226 79 dvdYQLF----TDSVREELLLgLKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPT 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:cd03226 155 SGLDYKNMERVGELIRELAAQ-GKAVIVITHDYEfLAKVCDRVLLLANGAI 204
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
7-200 |
9.00e-30 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 111.72 E-value: 9.00e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEV-KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDreltkYR 85
Cdd:COG1101 3 ELKNLSKTFNPGTVnEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPE-----YK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 R-DHVGFVFQ--FYNLVPSLTAYENVALVTEVAKS-PMRPA----------DALALV--GLEERMHHFPAQLSGGEQQRV 149
Cdd:COG1101 78 RaKYIGRVFQdpMMGTAPSMTIEENLALAYRRGKRrGLRRGltkkrrelfrELLATLglGLENRLDTKVGLLSGGQRQAL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 150 AIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN 200
Cdd:COG1101 158 SLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHN 208
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
27-211 |
9.79e-30 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 110.26 E-value: 9.79e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGG-LDRP--TSGSLFFRDLDLTEL--EDReltkyrrdHVGFVFQFYNLVPS 101
Cdd:COG4136 19 PLSLTVAPGEILTLMGPSGSGKSTLLAAIAGtLSPAfsASGEVLLNGRRLTALpaEQR--------RIGILFQDDLLFPH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENV--ALVTEVAKS--PMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:COG4136 91 LSVGENLafALPPTIGRAqrRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRA 170
|
170 180 190
....*....|....*....|....*....|....
gi 1869873813 178 RVIEALLGVNRQLGTTTVIITHNASIQGVADRVL 211
Cdd:COG4136 171 QFREFVFEQIRQRGIPALLVTHDEEDAPAAGRVL 204
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
25-218 |
1.03e-29 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 108.84 E-value: 1.03e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNLVPSLTA 104
Cdd:cd03246 18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNEL----GDHVGYLPQDDELFSGSIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 yENValvtevakspmrpadalalvgleermhhfpaqLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKtGIRVIEALL 184
Cdd:cd03246 94 -ENI--------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVE-GERALNQAI 139
|
170 180 190
....*....|....*....|....*....|....
gi 1869873813 185 GVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:cd03246 140 AALKAAGATRIVIAHRPETLASADRILVLEDGRV 173
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
4-219 |
1.31e-29 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 109.18 E-value: 1.31e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 4 AVFSAKALTKTYVSGEVKVHA--LNEVDLEITEKEVVVLLGPSGSGKTTLLNI-MGGLDRP-TSGSLFFRDldltelEDR 79
Cdd:cd03213 2 VTLSFRNLTVTVKSSPSKSGKqlLKNVSGKAKPGELTAIMGPSGAGKSTLLNAlAGRRTGLgVSGEVLING------RPL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELTKYRRdHVGFVFQFYNLVPSLTAYENVALvtevakspmrpadALALVGleermhhfpaqLSGGEQQRVAIARAIAKRP 159
Cdd:cd03213 76 DKRSFRK-IIGYVPQDDILHPTLTVRETLMF-------------AAKLRG-----------LSGGERKRVSIALELVSNP 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 160 AVLLCDEPTGALDSKTGIRVIEALLGVnRQLGTTTVIITHNASIQ--GVADRVLFFADGRIA 219
Cdd:cd03213 131 SLLFLDEPTSGLDSSSALQVMSLLRRL-ADTGRTIICSIHQPSSEifELFDKLLLLSQGRVI 191
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
25-219 |
4.37e-29 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 109.43 E-value: 4.37e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYR---RDHVGFVFQFynlvps 101
Cdd:COG4559 17 LDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRavlPQHSSLAFPF------ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 lTAYENVAL-----VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA-------KRPAVLLCDEPTG 169
Cdd:COG4559 91 -TVEEVVALgraphGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTS 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 170 ALDsktgIRVIEALLGVNRQL---GTTTVIITH--NASIQgVADRVLFFADGRIA 219
Cdd:COG4559 170 ALD----LAHQHAVLRLARQLarrGGGVVAVLHdlNLAAQ-YADRILLLHQGRLV 219
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
18-234 |
7.27e-29 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 108.85 E-value: 7.27e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 18 GEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGL-----DRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFV 92
Cdd:PRK14247 14 GQVEV--LDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMDVIEL----RRRVQMV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 93 FQFYNLVPSLTAYENVAL---VTEVAKSPM----RPADALALVGLEE----RMHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:PRK14247 88 FQIPNPIPNLSIFENVALglkLNRLVKSKKelqeRVRWALEKAQLWDevkdRLDAPAGKLSGGQQQRLCIARALAFQPEV 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLgtTTVIITH-NASIQGVADRVLFFADGRIARV-RTNEV-RREAAELT 234
Cdd:PRK14247 168 LLADEPTANLDPENTAKIESLFLELKKDM--TIVLVTHfPQQAARISDYVAFLYKGQIVEWgPTREVfTNPRHELT 241
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
24-234 |
9.00e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 109.72 E-value: 9.00e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQFynlvPSLT 103
Cdd:PRK13634 22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNKKLKPLRKKVGIVFQF----PEHQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALvTEVAKSPM-----------RPADALALVGL-EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PRK13634 98 LFEETVE-KDICFGPMnfgvseedakqKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 172 DSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIARVRT-NEVRREAAELT 234
Cdd:PRK13634 177 DPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEdAARYADQIVVMHKGTVFLQGTpREIFADPDELE 241
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
24-218 |
9.02e-29 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 108.09 E-value: 9.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ----FYNlv 99
Cdd:cd03251 17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASL----RRQIGLVSQdvflFND-- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 pslTAYENVALVTEVAkSPMRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:cd03251 91 ---TVAENIAYGRPGA-TREEVEEAARAANAHEFIMELPegydtvigergVKLSGGQRQRIAIARALLKDPPILILDEAT 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 169 GALDSKTGIRVIEAL--LGVNRqlgtTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:cd03251 167 SALDTESERLVQAALerLMKNR----TTFVIAHRLSTIENADRIVVLEDGKI 214
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
23-221 |
9.45e-29 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 108.78 E-value: 9.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGL-----DRPTSGS--LFFRDLDLTELEDRELtkyrRDHVGFVFQF 95
Cdd:PRK14267 18 HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEvrLFGRNIYSPDVDPIEV----RREVGMVFQY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLVPSLTAYENVA-------LVTEVAKSPMRPADALALVGL----EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLC 164
Cdd:PRK14267 94 PNPFPHLTIYDNVAigvklngLVKSKKELDERVEWALKKAALwdevKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLM 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 165 DEPTGALDSKTGIRVIEALLGVNRQLgtTTVIITHN-ASIQGVADRVLFFADGRIARV 221
Cdd:PRK14267 174 DEPTANIDPVGTAKIEELLFELKKEY--TIVLVTHSpAQAARVSDYVAFLYLGKLIEV 229
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
24-211 |
2.02e-28 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 111.99 E-value: 2.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdrelTKYRRDHVGFVFQFYNLVPSlT 103
Cdd:TIGR02857 337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADAD----ADSWRDQIAWVPQHPFLFAG-T 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAkSPMRPADALALVGLEE------RMHHFP-----AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:TIGR02857 412 IAENIRLARPDA-SDAEIREALERAGLDEfvaalpQGLDTPigeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLD 490
|
170 180 190
....*....|....*....|....*....|....*....
gi 1869873813 173 SKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVL 211
Cdd:TIGR02857 491 AETEAEVLEALRALAQ--GRTVLLVTHRLALAALADRIV 527
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
1-219 |
2.04e-28 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 109.28 E-value: 2.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTY------VSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLT 74
Cdd:PRK11308 1 SQQPLLQAIDLKKHYpvkrglFKPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 75 ElEDRELTKYRRDHVGFVFQfyNLVPSL--------TAYENVALVTEVAKSPMRP--ADALALVGLE-ERMHHFPAQLSG 143
Cdd:PRK11308 81 K-ADPEAQKLLRQKIQIVFQ--NPYGSLnprkkvgqILEEPLLINTSLSAAERREkaLAMMAKVGLRpEHYDRYPHMFSG 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 144 GEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:PRK11308 158 GQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSvVEHIADEVMVMYLGRCV 234
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-233 |
2.28e-28 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 111.66 E-value: 2.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSgevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRdldlteleDRE 80
Cdd:COG3845 1 MMPPALELRGITKRFGG----VVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILID--------GKP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LT-----KYRRDHVGFVFQFYNLVPSLTAYENVALVTEVAKSPMRPADALA--LVGLEERMhHFP-------AQLSGGEQ 146
Cdd:COG3845 69 VRirsprDAIALGIGMVHQHFMLVPNLTVAENIVLGLEPTKGGRLDRKAARarIRELSERY-GLDvdpdakvEDLSVGEQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 147 QRVAIARAIAKRPAVLLCDEPTGALdskTGIRViEALLGVNRQL---GTTTVIITHN-ASIQGVADRVLFFADGR-IARV 221
Cdd:COG3845 148 QRVEILKALYRGARILILDEPTAVL---TPQEA-DELFEILRRLaaeGKSIIFITHKlREVMAIADRVTVLRRGKvVGTV 223
|
250
....*....|...
gi 1869873813 222 RTNEV-RREAAEL 233
Cdd:COG3845 224 DTAETsEEELAEL 236
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
8-219 |
3.53e-28 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 106.30 E-value: 3.53e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDlTELEDRELtkyrRD 87
Cdd:cd03266 4 ADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFD-VVKEPAEA----RR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 HVGFVFQFYNLVPSLTAYENVALVTEVAKspMRPADALA-------LVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:cd03266 79 RLGFVSDSTGLYDRLTARENLEYFAGLYG--LKGDELTArleeladRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 161 VLLCDEPTGALD---SKTGIRVIEALlgvnRQLGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:cd03266 157 VLLLDEPTTGLDvmaTRALREFIRQL----RALGKCILFSTHIMQeVERLCDRVVVLHRGRVV 215
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
25-218 |
3.63e-28 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 107.09 E-value: 3.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSG---SLFFRDLDLTELedRELtkyrRDHVGFV--FQFYNLV 99
Cdd:COG1119 19 LDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGndvRLFGERRGGEDV--WEL----RKRIGLVspALQLRFP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 PSLTAyENVAL------------VTEVAKspMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEP 167
Cdd:COG1119 93 RDETV-LDVVLsgffdsiglyrePTDEQR--ERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILDEP 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 168 TGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS--IQGVaDRVLFFADGRI 218
Cdd:COG1119 170 TAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEeiPPGI-THVLLLKDGRV 221
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
25-219 |
4.60e-28 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 106.78 E-value: 4.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYR---RDHVGFVFQFynlvps 101
Cdd:PRK13548 18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRavlPQHSSLSFPF------ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 lTAYENVAL-----VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA------KRPAVLLCDEPTGA 170
Cdd:PRK13548 92 -TVEEVVAMgraphGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSA 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 171 LDsktgIRVIEALLGVNRQL----GTTTVIITH--NASIQgVADRVLFFADGRIA 219
Cdd:PRK13548 171 LD----LAHQHHVLRLARQLaherGLAVIVVLHdlNLAAR-YADRIVLLHQGRLV 220
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
8-218 |
5.35e-28 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 107.09 E-value: 5.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVSGEVkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLtELEDRELTKYRRD 87
Cdd:PRK13639 4 TRDLKYSYPDGTE---ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPI-KYDKKSLLEVRKT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 hVGFVFQfyNLVPSL---TAYENVAL--------VTEVAKspmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:PRK13639 80 -VGIVFQ--NPDDQLfapTVEEDVAFgplnlglsKEEVEK---RVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNASIQGV-ADRVLFFADGRI 218
Cdd:PRK13639 154 MKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKE-GITIIISTHDVDLVPVyADKVYVMSDGKI 215
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
21-218 |
7.78e-28 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 105.77 E-value: 7.78e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNLVP 100
Cdd:cd03254 15 KKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSL----RSMIGVVLQDTFLFS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SlTAYENVALVTEVAKSPmRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:cd03254 91 G-TIMENIRLGRPNATDE-EVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIARAMLRDPKILILDEATS 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 170 ALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:cd03254 169 NIDTETEKLIQEALEKLMK--GRTSIIIAHRLSTIKNADKILVLDDGKI 215
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
22-225 |
1.22e-27 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 109.89 E-value: 1.22e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLD--RPTSGSLFFR------------------------------ 69
Cdd:TIGR03269 13 KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIIYHvalcekcgyverpskvgepcpvcggtlepe 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 70 DLDLTELEDRELTKYRRdHVGFVFQ-FYNLVPSLTAYENVALVTEVA-----KSPMRPADALALVGLEERMHHFPAQLSG 143
Cdd:TIGR03269 93 EVDFWNLSDKLRRRIRK-RIAIMLQrTFALYGDDTVLDNVLEALEEIgyegkEAVGRAVDLIEMVQLSHRITHIARDLSG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 144 GEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITH-NASIQGVADRVLFFADGRIARVR 222
Cdd:TIGR03269 172 GEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHwPEVIEDLSDKAIWLENGEIKEEG 251
|
...
gi 1869873813 223 TNE 225
Cdd:TIGR03269 252 TPD 254
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
25-223 |
1.98e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 105.97 E-value: 1.98e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFY-NLVPSLT 103
Cdd:PRK13650 23 LNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDI----RHKIGMVFQNPdNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTE---VAKSPM--RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIR 178
Cdd:PRK13650 99 VEDDVAFGLEnkgIPHEEMkeRVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRLE 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 179 VIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIARVRT 223
Cdd:PRK13650 179 LIKTIKGIRDDYQMTVISITHDLDEVALSDRVLVMKNGQVESTST 223
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
14-220 |
2.59e-27 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 109.07 E-value: 2.59e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 14 TYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKyrrdHVGFVF 93
Cdd:COG4618 337 TVVPPGSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGR----HIGYLP 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 94 QFYNLVPSlTAYENVALVTEVakspmRPADALA---LVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRP 159
Cdd:COG4618 413 QDVELFDG-TIAENIARFGDA-----DPEKVVAaakLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDP 486
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 160 AVLLCDEPTGALDSkTGIR-VIEALLGVnRQLGTTTVIITHNASIQGVADRVLFFADGRIAR 220
Cdd:COG4618 487 RLVVLDEPNSNLDD-EGEAaLAAAIRAL-KARGATVVVITHRPSLLAAVDKLLVLRDGRVQA 546
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
24-218 |
3.82e-27 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 105.20 E-value: 3.82e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQFynlvPSLT 103
Cdd:PRK13643 21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQF----PESQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALvTEVAKSPMR-----------PADALALVGL-EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PRK13643 97 LFEETVL-KDVAFGPQNfgipkekaekiAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGL 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 172 DSKTGIRVIEALLGVNrQLGTTTVIITH-NASIQGVADRVLFFADGRI 218
Cdd:PRK13643 176 DPKARIEMMQLFESIH-QSGQTVVLVTHlMDDVADYADYVYLLEKGHI 222
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
25-225 |
3.82e-27 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 103.85 E-value: 3.82e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreLTKYRRdHVGFVFQ---------F 95
Cdd:cd03253 17 LKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVT---LDSLRR-AIGVVPQdtvlfndtiG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLV---PSLTAYE--NVALVTEVAKSPMRPADALA-LVGleERmhhfPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:cd03253 93 YNIRygrPDATDEEviEAAKAAQIHDKIMRFPDGYDtIVG--ER----GLKLSGGEKQRVAIARAILKNPPILLLDEATS 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 170 ALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRIARVRTNE 225
Cdd:cd03253 167 ALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVNADKIIVLKDGRIVERGTHE 220
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
3-218 |
1.04e-26 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 102.80 E-value: 1.04e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeledrELT 82
Cdd:COG1137 1 MMTLEAENLVKSYGKRTV----VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDIT-----HLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 83 KYRRDHVGF--------VFQfynlvpSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRV 149
Cdd:COG1137 72 MHKRARLGIgylpqeasIFR------KLTVEDNILAVLELRKLSkkereERLEELLEEFGITHLRKSKAYSLSGGERRRV 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 150 AIARAIAKRPAVLLCDEPTGALD--SKTGIRVIEALLgVNRQLGtttVIIT-HNA-SIQGVADRVLFFADGRI 218
Cdd:COG1137 146 EIARALATNPKFILLDEPFAGVDpiAVADIQKIIRHL-KERGIG---VLITdHNVrETLGICDRAYIISEGKV 214
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
9-233 |
1.42e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 103.28 E-value: 1.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDH 88
Cdd:PRK13647 8 EDLHFRYKDG---TKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWV----RSK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYN-LVPSLTAYENVA---LVTEVAKSPM--RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVL 162
Cdd:PRK13647 81 VGLVFQDPDdQVFSSTVWDDVAfgpVNMGLDKDEVerRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVI 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 163 LCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHNASIQGV-ADRVLFFADGRI-----ARVRTNEVRREAAEL 233
Cdd:PRK13647 161 VLDEPMAYLDPRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEwADQVIVLKEGRVlaegdKSLLTDEDIVEQAGL 236
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
6-218 |
3.08e-26 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 100.08 E-value: 3.08e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 6 FSAKALTKTYvsGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltkyR 85
Cdd:cd03247 1 LSINNVSFSY--PEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKA-----L 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 RDHVGFVFQFYNLVpSLTAYENVAlvtevakspmrpadalalvgleermhhfpAQLSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:cd03247 74 SSLISVLNQRPYLF-DTTLRNNLG-----------------------------RRFSGGERQRLALARILLQDAPIVLLD 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 166 EPTGALDSKTGIRVIEALLGVNRqlGTTTVIITHNasIQGV--ADRVLFFADGRI 218
Cdd:cd03247 124 EPTVGLDPITERQLLSLIFEVLK--DKTLIWITHH--LTGIehMDKILFLENGKI 174
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
24-225 |
3.88e-26 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 101.99 E-value: 3.88e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTkyrRDHVGFVFQFYNLVPSLT 103
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIA---RMGVVRTFQHVRLFREMT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYEN--VA--------LVTEVAKSP-MRPADALAL---------VGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:PRK11300 97 VIENllVAqhqqlktgLFSGLLKTPaFRRAESEALdraatwlerVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILM 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLF------FADGRIARVRTNE 225
Cdd:PRK11300 177 LDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKlVMGISDRIYVvnqgtpLANGTPEEIRNNP 245
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
15-211 |
4.20e-26 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 100.94 E-value: 4.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 15 YVSGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkYRRdHVGFVFQ 94
Cdd:PRK10247 15 YLAGDAKI--LNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEI---YRQ-QVSYCAQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 95 fynlVPSL---TAYENVALVTEVAK---SPMRPADALALVGLEERMHHFP-AQLSGGEQQRVAIARAIAKRPAVLLCDEP 167
Cdd:PRK10247 89 ----TPTLfgdTVYDNLIFPWQIRNqqpDPAIFLDDLERFALPDTILTKNiAELSGGEKQRISLIRNLQFMPKVLLLDEI 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 168 TGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVL 211
Cdd:PRK10247 165 TSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINHADKVI 208
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
23-218 |
4.25e-26 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 101.06 E-value: 4.25e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreltKYRRDH--VGFVFQFYNLVP 100
Cdd:TIGR03410 14 HILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLP-----PHERARagIAYVPQGREIFP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVALVTEVAKSPMR--PADALALVG-LEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTgaldskTGI 177
Cdd:TIGR03410 89 RLTVEENLLTGLAALPRRSRkiPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPT------EGI 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 178 ---------RVIEALlgvNRQLGTTTVIITHNASI-QGVADRVLFFADGRI 218
Cdd:TIGR03410 163 qpsiikdigRVIRRL---RAEGGMAILLVEQYLDFaRELADRYYVMERGRV 210
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
5-218 |
4.33e-26 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 101.20 E-value: 4.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 5 VFSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeledrELTKY 84
Cdd:TIGR04406 1 TLVAENLIKSYKKRKV----VNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDIT-----HLPMH 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 85 RRDHVGFVF--QFYNLVPSLTAYENVALVTEVAKSPMRPADALALVGLEERMH-----HFPAQ-LSGGEQQRVAIARAIA 156
Cdd:TIGR04406 72 ERARLGIGYlpQEASIFRKLTVEENIMAVLEIRKDLDRAEREERLEALLEEFQishlrDNKAMsLSGGERRRVEIARALA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 157 KRPAVLLCDEPTGALDSktgIRV--IEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRI 218
Cdd:TIGR04406 152 TNPKFILLDEPFAGVDP---IAVgdIKKIIKHLKERGIGVLITDHNVrETLDICDRAYIISDGKV 213
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
24-220 |
4.47e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 102.13 E-value: 4.47e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQFynlvPSLT 103
Cdd:PRK13649 22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIRKKVGLVFQF----PESQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALvTEVAKSPM-----------RPADALALVGL-EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PRK13649 98 LFEETVL-KDVAFGPQnfgvsqeeaeaLAREKLALVGIsESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGL 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 172 DSKtGIRVIEALLGVNRQLGTTTVIITH-NASIQGVADRVLFFADGRIAR 220
Cdd:PRK13649 177 DPK-GRKELMTLFKKLHQSGMTIVLVTHlMDDVANYADFVYVLEKGKLVL 225
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
9-218 |
6.91e-26 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 105.18 E-value: 6.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDH 88
Cdd:TIGR02203 334 RNVTFRYPGRDRP--ALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASL----RRQ 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSlTAYENVA------LVTEVAKSPMRPADALALV-----GLEERMHHFPAQLSGGEQQRVAIARAIAK 157
Cdd:TIGR02203 408 VALVSQDVVLFND-TIANNIAygrteqADRAEIERALAAAYAQDFVdklplGLDTPIGENGVLLSGGQRQRLAIARALLK 486
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 158 RPAVLLCDEPTGALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:TIGR02203 487 DAPILILDEATSALDNESERLVQAALERLMQ--GRTTLVIAHRLSTIEKADRIVVMDDGRI 545
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
24-218 |
1.24e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 100.83 E-value: 1.24e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdrELTKYRRdHVGFVFQ------FYN 97
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFS--KLQGIRK-LVGIVFQnpetqfVGR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 LVPSLTAY--ENVALV-TEVAKspmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSK 174
Cdd:PRK13644 94 TVEEDLAFgpENLCLPpIEIRK---RVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPD 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 175 TGIRVIEALLGVNRQlGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK13644 171 SGIAVLERIKKLHEK-GKTIVYITHNLEELHDADRIIVMDRGKI 213
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
11-218 |
1.80e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 100.65 E-value: 1.80e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSgevKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYrrdhVG 90
Cdd:PRK13652 9 LCYSYSG---SKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKF----VG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQ------FYNLVPSLTAYENVALVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLC 164
Cdd:PRK13652 82 LVFQnpddqiFSPTVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 165 DEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:PRK13652 162 DEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDlVPEMADYIYVMDKGRI 216
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1-217 |
2.06e-25 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 101.34 E-value: 2.06e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKT-TLLNIMGGLDRP--TSGSLFFRDLDLTELE 77
Cdd:PRK09473 8 QADALLDVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMGLLAANgrIGGSATFNGREILNLP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 78 DRELTKYRRDHVGFVFQfyNLVPSLTAYENVA-LVTEV-------AKS-----PMRPADALALVGLEERMHHFPAQLSGG 144
Cdd:PRK09473 88 EKELNKLRAEQISMIFQ--DPMTSLNPYMRVGeQLMEVlmlhkgmSKAeafeeSVRMLDAVKMPEARKRMKMYPHEFSGG 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 145 EQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGR 217
Cdd:PRK09473 166 MRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDlGVVAGICDKVLVMYAGR 239
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
4-218 |
2.08e-25 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 101.36 E-value: 2.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 4 AVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKT-TLLNIMGGLDRP---TSGSLFFRDLDLTELEDR 79
Cdd:PRK11022 2 ALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPgrvMAEKLEFNGQDLQRISEK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELTKYRRDHVGFVFQ--FYNLVPSLTAYENVALVTEV------AKSPMRPADALALVGL---EERMHHFPAQLSGGEQQR 148
Cdd:PRK11022 82 ERRNLVGAEVAMIFQdpMTSLNPCYTVGFQIMEAIKVhqggnkKTRRQRAIDLLNQVGIpdpASRLDVYPHQLSGGMSQR 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 149 VAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:PRK11022 162 VMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDlALVAEAAHKIIVMYAGQV 232
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
24-213 |
6.49e-25 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 98.70 E-value: 6.49e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLL---NIMGGL--DRPTSGSLFFRDLDLTElEDRELTKYRRdHVGFVFQFYNL 98
Cdd:PRK14243 25 AVKNVWLDIPKNQITAFIGPSGCGKSTILrcfNRLNDLipGFRVEGKVTFHGKNLYA-PDVDPVEVRR-RIGMVFQKPNP 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSlTAYENVAL----------VTEVAKSPMRPA-------DALALVGLeermhhfpaQLSGGEQQRVAIARAIAKRPAV 161
Cdd:PRK14243 103 FPK-SIYDNIAYgaringykgdMDELVERSLRQAalwdevkDKLKQSGL---------SLSGGQQQRLCIARAIAVQPEV 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLgtTTVIITHNASIQG-VADRVLFF 213
Cdd:PRK14243 173 ILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAArVSDMTAFF 223
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
25-220 |
9.18e-25 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 98.75 E-value: 9.18e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLT-ELEDRELTKYRRDhVGFVFQFynlvPSLT 103
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpETGNKNLKKLRKK-VSLVFQF----PEAQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALvTEVAKSPM------RPADALAL-----VGL-EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PRK13641 98 LFENTVL-KDVEFGPKnfgfseDEAKEKALkwlkkVGLsEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGL 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 172 DSKTGIRVIEALLGVNRQlGTTTVIITHNA-SIQGVADRVLFFADGRIAR 220
Cdd:PRK13641 177 DPEGRKEMMQLFKDYQKA-GHTVILVTHNMdDVAEYADDVLVLEHGKLIK 225
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
3-226 |
9.33e-25 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 98.37 E-value: 9.33e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVS-----GEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDldlTELE 77
Cdd:COG4167 2 SALLEVRNLSKTFKYrtglfRRQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILING---HKLE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 78 DRElTKYRRDHVGFVFQFYN--LVPSLTayenvalVTEVAKSPMRPA-------------DALALVGL-EERMHHFPAQL 141
Cdd:COG4167 79 YGD-YKYRCKHIRMIFQDPNtsLNPRLN-------IGQILEEPLRLNtdltaeereerifATLRLVGLlPEHANFYPHML 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 142 SGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVLFFADGR-IA 219
Cdd:COG4167 151 SSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKLGISYIYVSQHLGIvKHISDKVLVMHQGEvVE 230
|
....*..
gi 1869873813 220 RVRTNEV 226
Cdd:COG4167 231 YGKTAEV 237
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
24-218 |
1.11e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 98.28 E-value: 1.11e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQfyN----LV 99
Cdd:PRK13648 24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKL----RKHIGIVFQ--NpdnqFV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 PSLTAY------ENVALVTEVAKSpmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDS 173
Cdd:PRK13648 98 GSIVKYdvafglENHAVPYDEMHR--RVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDP 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 174 KTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK13648 176 DARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTV 220
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
3-218 |
1.23e-24 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 97.98 E-value: 1.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVSGEvkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD-----LDLTELE 77
Cdd:TIGR02323 1 KPLLQVSGLSKSYGGGK----GCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYIMrsgaeLELYQLS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 78 DRELTKYRRDHVGFVFQFynlvPSLTAYENVALVTEVAKSPMRPAD-------ALALVGLEE------RMHHFPAQLSGG 144
Cdd:TIGR02323 77 EAERRRLMRTEWGFVHQN----PRDGLRMRVSAGANIGERLMAIGArhygnirATAQDWLEEveidptRIDDLPRAFSGG 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 145 EQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:TIGR02323 153 MQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLGLAVIIVTHDlGVARLLAQRLLVMQQGRV 227
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-218 |
2.31e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 97.61 E-value: 2.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFF--RDLDLTELED 78
Cdd:PRK13636 1 MEDYILKVEELNYNYSDG---THALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFdgKPIDYSRKGL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 79 RELtkyrRDHVGFVFQFY-NLVPSLTAYENVALVTEVAKSP-----MRPADALALVGLEERMHHFPAQLSGGEQQRVAIA 152
Cdd:PRK13636 78 MKL----RESVGMVFQDPdNQLFSASVYQDVSFGAVNLKLPedevrKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 153 RAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGV-ADRVLFFADGRI 218
Cdd:PRK13636 154 GVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLyCDNVFVMKEGRV 220
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
24-211 |
2.34e-24 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 95.38 E-value: 2.34e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlteledrelTKYRRDHVGFVFQFYNLVPSL- 102
Cdd:NF040873 7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV---------------RRAGGARVAYVPQRSEVPDSLp 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 -TAYENVALVTEVAKSPMRP---------ADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:NF040873 72 lTVRDLVAMGRWARRGLWRRltrddraavDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLD 151
|
170 180 190
....*....|....*....|....*....|....*....
gi 1869873813 173 SKTgIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVL 211
Cdd:NF040873 152 AES-RERIIALLAEEHARGATVVVVTHDLELVRRADPCV 189
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
28-201 |
2.43e-24 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 95.50 E-value: 2.43e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 28 VDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltkyRRDHVGFVFQFYNLVPSLTAYEN 107
Cdd:TIGR01189 19 LSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDE-----PHENILYLGHLPGLKPELSALEN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 108 VALVTEVAKSPMR-PADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDsKTGIRVIEALLGV 186
Cdd:TIGR01189 94 LHFWAAIHGGAQRtIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALD-KAGVALLAGLLRA 172
|
170
....*....|....*
gi 1869873813 187 NRQLGTTTVIITHNA 201
Cdd:TIGR01189 173 HLARGGIVLLTTHQD 187
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-217 |
3.40e-24 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 100.16 E-value: 3.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKT-TLLNIMGGLDRP----TSGSLFFRDLDLTE 75
Cdd:PRK15134 1 MTQPLLAIENLSVAFRQQQTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLLH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 76 LEDRELTKYRRDHVGFVFQ--------FYNLVPSLtaYENVAL----VTEVAKSPMrpADALALVGLEE---RMHHFPAQ 140
Cdd:PRK15134 81 ASEQTLRGVRGNKIAMIFQepmvslnpLHTLEKQL--YEVLSLhrgmRREAARGEI--LNCLDRVGIRQaakRLTDYPHQ 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVLFFADGR 217
Cdd:PRK15134 157 LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIvRKLADRVAVMQNGR 234
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
27-172 |
3.45e-24 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 98.41 E-value: 3.45e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE-LTKYRRdHVGFVFQFYNLVPSLTAY 105
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGIcLPPEKR-RIGYVFQDARLFPHYKVR 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 106 ENvaLVTEVAKSpMRP--ADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:PRK11144 95 GN--LRYGMAKS-MVAqfDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLD 160
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
16-218 |
3.69e-24 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 100.04 E-value: 3.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 16 VSGEVKVH-----------ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtky 84
Cdd:PRK13657 331 VKGAVEFDdvsfsydnsrqGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASL--- 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 85 rRDHVGFVFQFYNLVpSLTAYENVALVTEVA-KSPMRPA--DALALVGLEERMHHFPA-------QLSGGEQQRVAIARA 154
Cdd:PRK13657 408 -RRNIAVVFQDAGLF-NRSIEDNIRVGRPDAtDEEMRAAaeRAQAHDFIERKPDGYDTvvgergrQLSGGERQRLAIARA 485
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 155 IAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK13657 486 LLKDPPILILDEATSALDVETEAKVKAALDELMK--GRTTFIIAHRLSTVRNADRILVFDNGRV 547
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
24-218 |
4.23e-24 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 97.39 E-value: 4.23e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDL-TELEDRELTKYRRDHVGFVFQF--YNL-- 98
Cdd:PRK13645 26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpANLKKIKEVKRLRKEIGLVFQFpeYQLfq 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 --VPSLTAYENVALVTEVAKSPMRPADALALVGL-EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:PRK13645 106 etIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKG 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 176 GIRVIEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRI 218
Cdd:PRK13645 186 EEDFINLFERLNKEYKKRIIMVTHNMdQVLRIADEVIVMHEGKV 229
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
25-218 |
4.61e-24 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 96.70 E-value: 4.61e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDL---TELEDRELTKYRRdHVGFVFQFYNLVPs 101
Cdd:PRK14271 37 LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLggrSIFNYRDVLEFRR-RVGMLFQRPNPFP- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVALVTEVAKSPMRP-----ADA-LALVGL----EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PRK14271 115 MSIMDNVLAGVRAHKLVPRKefrgvAQArLTEVGLwdavKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSAL 194
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 172 DSKTGIRVIEALLGVNRQLgtTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:PRK14271 195 DPTTTEKIEEFIRSLADRL--TVIIVTHNlAQAARISDRAALFFDGRL 240
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
23-219 |
6.13e-24 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 99.74 E-value: 6.13e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYrrdhVGFVFQFYNLVPSL 102
Cdd:TIGR00955 39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSGSVLLNGMPIDAKEMRAI----SAYVQQDDLFIPTL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYEN------VALVTEVAKSPMRPA-----DALAL-------VGLEERMHhfpaQLSGGEQQRVAIARAIAKRPAVLLC 164
Cdd:TIGR00955 115 TVREHlmfqahLRMPRRVTKKEKRERvdevlQALGLrkcantrIGVPGRVK----GLSGGERKRLAFASELLTDPPLLFC 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 165 DEPTGALDSKTGIRVIEALLGVNrQLGTTTVIITHNAS--IQGVADRVLFFADGRIA 219
Cdd:TIGR00955 191 DEPTSGLDSFMAYSVVQVLKGLA-QKGKTIICTIHQPSseLFELFDKIILMAEGRVA 246
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
24-219 |
9.14e-24 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 95.25 E-value: 9.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreLTKYRRdHVGFVFQfYNLVPSLT 103
Cdd:cd03252 17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALAD---PAWLRR-QVGVVLQ-ENVLFNRS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALvTEVAKSPMRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:cd03252 92 IRDNIAL-ADPGMSMERVIEAAKLAGAHDFISELPegydtivgeqgAGLSGGQRQRIAIARALIHNPRILIFDEATSALD 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 173 SKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRIA 219
Cdd:cd03252 171 YESEHAIMRNMHDICA--GRTVIIIAHRLSTVKNADRIIVMEKGRIV 215
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
27-218 |
1.03e-23 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 95.60 E-value: 1.03e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRdHVGFVFQFYNLVPSLTAYE 106
Cdd:PRK11831 25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRK-RMSMLFQSGALFTDMNVFD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 107 NVA--------LVTEVAKSP-MRPADALALVGLEERMhhfPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:PRK11831 104 NVAyplrehtqLPAPLLHSTvMMKLEAVGLRGAAKLM---PSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMG 180
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1869873813 178 RVIEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRI 218
Cdd:PRK11831 181 VLVKLISELNSALGVTCVVVSHDVpEVLSIADHAYIVADKKI 222
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
22-218 |
1.14e-23 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 94.71 E-value: 1.14e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffRDLDLTELEDREltKYRRdHVGFVF-QFYNLVP 100
Cdd:cd03267 34 VEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEV--RVAGLVPWKRRK--KFLR-RIGVVFgQKTQLWW 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVALVTEVAKSPMRPA----DALA-LVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:cd03267 109 DLPVIDSFYLLAAIYDLPPARFkkrlDELSeLLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVA 188
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 176 GIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:cd03267 189 QENIRNFLKEYNRERGTTVLLTSHYmKDIEALARRVLVIDKGRL 232
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
27-199 |
1.48e-23 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 93.72 E-value: 1.48e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDReltkYRRD-----HVGFVfqfynlVPS 101
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDE----YHQDllylgHQPGI------KTE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVALVTEVAKSPMRPA--DALALVGLEERMHHFPAQLSGGEQQRVAIAR-AIAKRPAVLLcDEPTGALDsKTGIR 178
Cdd:PRK13538 89 LTALENLRFYQRLHGPGDDEAlwEALAQVGLAGFEDVPVRQLSAGQQRRVALARlWLTRAPLWIL-DEPFTAID-KQGVA 166
|
170 180
....*....|....*....|.
gi 1869873813 179 VIEALLGVNRQLGTTTVIITH 199
Cdd:PRK13538 167 RLEALLAQHAEQGGMVILTTH 187
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-218 |
2.09e-23 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 94.61 E-value: 2.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGevkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD-----LDLTE 75
Cdd:PRK11701 2 MDQPLLSVRGLTKLYGPR----KGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMrdgqlRDLYA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 76 LEDRELTKYRRDHVGFVFQfyN----LVPSLTAYENV-----AL-------VTEVAkspmrpADALALVGLE-ERMHHFP 138
Cdd:PRK11701 78 LSEAERRRLLRTEWGFVHQ--HprdgLRMQVSAGGNIgerlmAVgarhygdIRATA------GDWLERVEIDaARIDDLP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 139 AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGR 217
Cdd:PRK11701 150 TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDlAVARLLAHRLLVMKQGR 229
|
.
gi 1869873813 218 I 218
Cdd:PRK11701 230 V 230
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
21-230 |
4.09e-23 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 93.40 E-value: 4.09e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTeleDRELTKYRRDHVGFVFQFYNLVP 100
Cdd:PRK11614 17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDIT---DWQTAKIMREAVAIVPEGRRVFS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVAL---VTEVAKSPMRPADALALVG-LEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTG 176
Cdd:PRK11614 94 RMTVEENLAMggfFAERDQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLGLAPIII 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 177 IRVIEALLGVnRQLGTTTVIITHNAS-IQGVADRVLFFADGRI------ARVRTNEVRREA 230
Cdd:PRK11614 174 QQIFDTIEQL-REQGMTIFLVEQNANqALKLADRGYVLENGHVvledtgDALLANEAVRSA 233
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
28-218 |
5.84e-23 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 96.84 E-value: 5.84e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 28 VDLEITEKEVVVLLGPSGSGKTTLLN-IMGGLdrPTSGSLFFRDLDLTELEdreLTKYRRdHVGFVFQfyNlvPSL---T 103
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNaLLGFL--PYQGSLKINGIELRELD---PESWRK-HLSWVGQ--N--PQLphgT 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAkSPMRPADALALVGLEERMHHFP-----------AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:PRK11174 439 LRDNVLLGNPDA-SDEQLQQALENAWVSEFLPLLPqgldtpigdqaAGLSVGQAQRLALARALLQPCQLLLLDEPTASLD 517
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1869873813 173 SKTGIRVIEALLGVNRqlGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK11174 518 AHSEQLVMQALNAASR--RQTTLMVTHQLEDLAQWDQIWVMQDGQI 561
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
24-200 |
6.79e-23 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 96.28 E-value: 6.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNLVPSlT 103
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEV----RRRVSVCAQDAHLFDT-T 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAkSPMRPADALALVGLEE-----------RMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:TIGR02868 425 VRENLRLARPDA-TDEELWAALERVGLADwlralpdgldtVLGEGGARLSGGERQRLALARALLADAPILLLDEPTEHLD 503
|
170 180
....*....|....*....|....*...
gi 1869873813 173 SKTGIRVIEALLGVNRqlGTTTVIITHN 200
Cdd:TIGR02868 504 AETADELLEDLLAALS--GRTVVLITHH 529
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
9-230 |
8.46e-23 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 92.84 E-value: 8.46e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKyrrdH 88
Cdd:COG4604 5 KNVSKRY--GGKVV--LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAK----R 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALvtevAKSP-----MRPAD------ALALVGLEERMHHFPAQLSGGEQQRVAIARAIAK 157
Cdd:COG4604 77 LAILRQENHINSRLTVRELVAF----GRFPyskgrLTAEDreiideAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQ 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 158 RPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN---ASiqGVADRVLFFADGRIARV-RTNEVRREA 230
Cdd:COG4604 153 DTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDinfAS--CYADHIVAMKDGRVVAQgTPEEIITPE 227
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
21-210 |
1.06e-22 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 94.20 E-value: 1.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGGLD---RPTSGSLFFRDLDLTELEDRELTKYRRDHVGFVFQ-- 94
Cdd:COG4170 19 RVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKaICGITKdnwHVTADRFRWNGIDLLKLSPRERRKIIGREIAMIFQep 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 95 FYNLVPSLTAYENV--ALVTEVAKSPM------RPADALAL---VGL---EERMHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:COG4170 99 SSCLDPSAKIGDQLieAIPSWTFKGKWwqrfkwRKKRAIELlhrVGIkdhKDIMNSYPHELTEGECQKVMIAMAIANQPR 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 161 VLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRV 210
Cdd:COG4170 179 LLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDlESISQWADTI 229
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
25-226 |
1.06e-22 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 92.80 E-value: 1.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDR------PTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNL 98
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIFQIDAIKL----RKEVGMVFQQPNP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLTAYENVAL------VTEVAKSPMRPADALALVGL----EERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:PRK14246 102 FPHLSIYDNIAYplkshgIKEKREIKKIVEECLRKVGLwkevYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPT 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLgtTTVIITHN-ASIQGVADRVLFFADGRIARV-RTNEV 226
Cdd:PRK14246 182 SMIDIVNSQAIEKLITELKNEI--AIVIVSHNpQQVARVADYVAFLYNGELVEWgSSNEI 239
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-216 |
1.08e-22 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 95.62 E-value: 1.08e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSgevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE 80
Cdd:PRK09700 1 MATPYISMAGIGKSFGP----VHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYrrdHVGFVFQFYNLVPSLTAYENVAL------------VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQR 148
Cdd:PRK09700 77 AAQL---GIGIIYQELSVIDELTVLENLYIgrhltkkvcgvnIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQM 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 149 VAIARAIAKRPAVLLCDEPTGALDSKTgirvIEALLGVNRQL---GTTTVIITHN-ASIQGVADRVLFFADG 216
Cdd:PRK09700 154 LEIAKTLMLDAKVIIMDEPTSSLTNKE----VDYLFLIMNQLrkeGTAIVYISHKlAEIRRICDRYTVMKDG 221
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
3-218 |
1.67e-22 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 90.18 E-value: 1.67e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTyvsgevkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELt 82
Cdd:cd03215 2 EPVLEVRGLSVK--------GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDA- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 83 kyRRDHVGFV---FQFYNLVPSLTAYENVALvtevakspmrpadalalvgleermhhfPAQLSGGEQQRVAIARAIAKRP 159
Cdd:cd03215 73 --IRAGIAYVpedRKREGLVLDLSVAENIAL---------------------------SSLLSGGNQQKVVLARWLARDP 123
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 160 AVLLCDEPTGALDSKTgIRVIEALLGVNRQLGTTTVII-THNASIQGVADRVLFFADGRI 218
Cdd:cd03215 124 RVLILDEPTRGVDVGA-KAEIYRLIRELADAGKAVLLIsSELDELLGLCDRILVMYEGRI 182
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
24-211 |
2.89e-22 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 92.85 E-value: 2.89e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDhVGFVFQ--FYNLVPS 101
Cdd:PRK15079 36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRSD-IQMIFQdpLASLNPR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVALVTEVAKSPMRPADA-------LALVGLEERM-HHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDS 173
Cdd:PRK15079 115 MTIGEIIAEPLRTYHPKLSRQEVkdrvkamMLKVGLLPNLiNRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDV 194
|
170 180 190
....*....|....*....|....*....|....*....
gi 1869873813 174 KTGIRVIEALLGVNRQLGTTTVIITHNASI-QGVADRVL 211
Cdd:PRK15079 195 SIQAQVVNLLQQLQREMGLSLIFIAHDLAVvKHISDRVL 233
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
25-219 |
9.28e-22 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 93.35 E-value: 9.28e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ---------F 95
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASL----RAAIGIVPQdtvlfndtiA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLvpsltAYENV----ALVTEVAKspmrpadaLAlvgleeRMHHFPAQ---------------LSGGEQQRVAIARAIA 156
Cdd:COG5265 450 YNI-----AYGRPdaseEEVEAAAR--------AA------QIHDFIESlpdgydtrvgerglkLSGGEKQRVAIARTLL 510
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIEALLGVNRqlGTTTVIITHNAS-IQGvADRVLFFADGRIA 219
Cdd:COG5265 511 KNPPILIFDEATSALDSRTERAIQAALREVAR--GRTTLVIAHRLStIVD-ADEILVLEAGRIV 571
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
25-213 |
1.10e-21 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 90.10 E-value: 1.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTL---LNIMGGLDRPT--SGSLFFRDLDLTElEDRELTKYRRdHVGFVFQFYNLV 99
Cdd:PRK14258 23 LEGVSMEIYQSKVTAIIGPSGCGKSTFlkcLNRMNELESEVrvEGRVEFFNQNIYE-RRVNLNRLRR-QVSMVHPKPNLF 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 PsLTAYENVAL------------VTEVAKSPMRPADALALVglEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEP 167
Cdd:PRK14258 101 P-MSVYDNVAYgvkivgwrpkleIDDIVESALKDADLWDEI--KHKIHKSALDLSGGQQQRLCIARALAVKPKVLLMDEP 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 168 TGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFF 213
Cdd:PRK14258 178 CFGLDPIASMKVESLIQSLRLRSELTMVIVSHNlHQVSRLSDFTAFF 224
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
21-218 |
1.47e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 91.07 E-value: 1.47e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELT------------KYRRDH 88
Cdd:PRK13631 38 ELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNNHELitnpyskkiknfKELRRR 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQF--YNL----VPSLTAYENVALVTEVAKSPMRPADALALVGLEER-MHHFPAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:PRK13631 118 VSMVFQFpeYQLfkdtIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLDDSyLERSPFGLSGGQKRRVAIAGILAIQPEI 197
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 162 LLCDEPTGALDSKtGIRVIEALLGVNRQLGTTTVIITHNA-SIQGVADRVLFFADGRI 218
Cdd:PRK13631 198 LIFDEPTAGLDPK-GEHEMMQLILDAKANNKTVFVITHTMeHVLEVADEVIVMDKGKI 254
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
1-218 |
1.93e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 89.86 E-value: 1.93e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE 80
Cdd:PRK13640 1 MKDNIVEFKHVSFTY--PDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKITVDGITLTAKT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYRrDHVGFVFQFY-NLVPSLTAYENVALVTE---VAKSPMRP--ADALALVGLEERMHHFPAQLSGGEQQRVAIARA 154
Cdd:PRK13640 79 VWDIR-EKVGIVFQNPdNQFVGATVGDDVAFGLEnraVPRPEMIKivRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGI 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 155 IAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK13640 158 LAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANMADQVLVLDDGKL 221
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
24-218 |
2.17e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 89.84 E-value: 2.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLT-ELEDRELTKYRRDhVGFVFQFynlvPSL 102
Cdd:PRK13646 22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIThKTKDKYIRPVRKR-IGMVFQF----PES 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYE------------NVALVTEVAKSpmRPADALALVGLEER-MHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:PRK13646 97 QLFEdtvereiifgpkNFKMNLDEVKN--YAHRLLMDLGFSRDvMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTA 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 170 ALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:PRK13646 175 GLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNeVARYADEVIVMKEGSI 224
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
7-218 |
3.98e-21 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 87.34 E-value: 3.98e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYvsGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFrdldltelEDRELTKYRR 86
Cdd:cd03269 2 EVENVTKRF--GRVT--ALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLF--------DGKPLDIAAR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQFYNLVPSLTAYENVALVTEVAKspMRPADALALV-------GLEERMHHFPAQLSGGEQQRVAIARAIAKRP 159
Cdd:cd03269 70 NRIGYLPEERGLYPKMKVIDQLVYLAQLKG--LKKEEARRRIdewlerlELSEYANKRVEELSKGNQQKVQFIAAVIHDP 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 160 AVLLCDEPTGALDSkTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:cd03269 148 ELLILDEPFSGLDP-VNVELLKDVIRELARAGKTVILSTHQmELVEELCDRVLLLNKGRA 206
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
28-200 |
7.82e-21 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 86.47 E-value: 7.82e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 28 VDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKY--RRDhvgfvfqfyNLVPSLTAY 105
Cdd:PRK13539 21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAEACHYlgHRN---------AMKPALTVA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 106 ENVALVTEV-AKSPMRPADALALVGLeERMHHFPAQ-LSGGEQQRVAIAR-AIAKRPAVLLcDEPTGALDSkTGIRVIEA 182
Cdd:PRK13539 92 ENLEFWAAFlGGEELDIAAALEAVGL-APLAHLPFGyLSAGQKRRVALARlLVSNRPIWIL-DEPTAALDA-AAVALFAE 168
|
170
....*....|....*...
gi 1869873813 183 LLGVNRQLGTTTVIITHN 200
Cdd:PRK13539 169 LIRAHLAQGGIVIAATHI 186
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
7-218 |
8.12e-21 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 88.99 E-value: 8.12e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTY--------VSGEVK---------VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffR 69
Cdd:COG4586 3 EVENLSKTYrvyekepgLKGALKglfrreyreVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEV--R 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 70 DLDLTELEDREltKYRRdHVGFVF-QFYNLVPSLTAYENVALVTEVAKSPMRPA----DALA-LVGLEERMHHFPAQLSG 143
Cdd:COG4586 81 VLGYVPFKRRK--EFAR-RIGVVFgQRSQLWWDLPAIDSFRLLKAIYRIPDAEYkkrlDELVeLLDLGELLDTPVRQLSL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 144 GEQQRVAIARAIAKRPAVLLCDEPTGALD--SKTGIRviEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG4586 158 GQRMRCELAAALLHRPKILFLDEPTIGLDvvSKEAIR--EFLKEYNRERGTTILLTSHDmDDIEALCDRVIVIDHGRI 233
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
36-218 |
8.70e-21 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 90.55 E-value: 8.70e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 36 EVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDreltKYRRDHVGFVFQFYNLVpSLTAYENVAL-VTEV 114
Cdd:TIGR00958 508 EVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDH----HYLHRQVALVGQEPVLF-SGSVRENIAYgLTDT 582
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 115 AKSPMRPADALALV---------GLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKtgirvIEALLG 185
Cdd:TIGR00958 583 PDEEIMAAAKAANAhdfimefpnGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAE-----CEQLLQ 657
|
170 180 190
....*....|....*....|....*....|....
gi 1869873813 186 VNRQLGTTTVI-ITHNASIQGVADRVLFFADGRI 218
Cdd:TIGR00958 658 ESRSRASRTVLlIAHRLSTVERADQILVLKKGSV 691
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
25-220 |
1.09e-20 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 87.04 E-value: 1.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGGLD-RPTSGSLFFRDLDLTELEDREltkyR-RDHVGFVFQ------- 94
Cdd:COG0396 16 LKGVNLTIKPGEVHAIMGPNGSGKSTLAKvLMGHPKyEVTSGSILLDGEDILELSPDE----RaRAGIFLAFQypveipg 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 95 --FYNLVpsLTAYENVALVTEVAKSPMRPA-DALALVGLEERMhhfpAQ------LSGGEQQRVAIARAIAKRPAVLLCD 165
Cdd:COG0396 92 vsVSNFL--RTALNARRGEELSAREFLKLLkEKMKELGLDEDF----LDryvnegFSGGEKKRNEILQMLLLEPKLAILD 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 166 EPTGALDsktgirvIEAL----LGVN--RQLGTTTVIITHNASI--QGVADRVLFFADGRIAR 220
Cdd:COG0396 166 ETDSGLD-------IDALrivaEGVNklRSPDRGILIITHYQRIldYIKPDFVHVLVDGRIVK 221
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
7-217 |
1.57e-20 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 84.04 E-value: 1.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlteledreltkyrr 86
Cdd:cd03221 2 ELENLSKTYGGKLL----LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIV-------------------- 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 dhvgfvfqfynlvpsltayenvalvtevakspmrpadalaLVGLEERMHHFPaQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:cd03221 58 ----------------------------------------TWGSTVKIGYFE-QLSGGEKMRLALAKLLLENPNLLLLDE 96
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 167 PTGALDSKTGIRVIEALLGVNRqlgtTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:cd03221 97 PTNHLDLESIEALEEALKEYPG----TVILVSHDRYfLDQVATKIIELEDGK 144
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
8-218 |
1.81e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 89.35 E-value: 1.81e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRdldlteledreltkyRRD 87
Cdd:COG0488 1 LENLSKSF--GGRPL--LDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIP---------------KGL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 HVGFVFQFYNLVPSLTAYENV--------ALVTEVAKSPMRPAD-----------------------------ALALVGL 130
Cdd:COG0488 62 RIGYLPQEPPLDDDLTVLDTVldgdaelrALEAELEELEAKLAEpdedlerlaelqeefealggweaearaeeILSGLGF 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 131 EERMHHFP-AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTgIRVIEALLgvnRQLGTTTVIITH-----NAsiq 204
Cdd:COG0488 142 PEEDLDRPvSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLES-IEWLEEFL---KNYPGTVLVVSHdryflDR--- 214
|
250
....*....|....
gi 1869873813 205 gVADRVLFFADGRI 218
Cdd:COG0488 215 -VATRILELDRGKL 227
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
25-218 |
1.81e-20 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 85.99 E-value: 1.81e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdLDLTELEDRElTKYRRDHVGFVFQ----FYNLVP 100
Cdd:cd03248 30 LQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVL---LDGKPISQYE-HKYLHSKVSLVGQepvlFARSLQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 SLTAYENVALVTEVAKSPMRPADALALV-----GLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:cd03248 106 DNIAYGLQSCSFECVKEAAQKAHAHSFIselasGYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAES 185
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1869873813 176 GIRVIEALLGVNRQlgTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:cd03248 186 EQQVQQALYDWPER--RTVLVIAHRLSTVERADQILVLDGGRI 226
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
24-217 |
3.15e-20 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 84.83 E-value: 3.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGGLDRpTSGSLFFRDldlteledreltkyrrdHVGFVFQFYNLVpSL 102
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSaLLGELEK-LSGSVSVPG-----------------SIAYVSQEPWIQ-NG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYENValvteVAKSPMRPA---DALALVGLEERMHHFPAQ-----------LSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:cd03250 81 TIRENI-----LFGKPFDEEryeKVIKACALEPDLEILPDGdlteigekginLSGGQKQRISLARAVYSDADIYLLDDPL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGR 217
Cdd:cd03250 156 SAVDAHVGRHIFENCILGLLLNNKTRILVTHQLQLLPHADQIVVLDNGR 204
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
11-210 |
3.20e-20 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 87.17 E-value: 3.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLD----RPTSGSLFFRDLDLTELEDRELTKYRR 86
Cdd:PRK15093 9 LTIEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTkdnwRVTADRMRFDDIDLLRLSPRERRKLVG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGFVFQFYN--LVPSltayENVA--LVTEVAKSPM-------------RPADALALVGLEER---MHHFPAQLSGGEQ 146
Cdd:PRK15093 89 HNVSMIFQEPQscLDPS----ERVGrqLMQNIPGWTYkgrwwqrfgwrkrRAIELLHRVGIKDHkdaMRSFPYELTEGEC 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 147 QRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRV 210
Cdd:PRK15093 165 QKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDlQMLSQWADKI 229
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
19-199 |
3.60e-20 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 85.40 E-value: 3.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 19 EVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGG--LDRPTSGSLFFRDLDLteleDRELTkyrrdhvgfvfqfy 96
Cdd:COG2401 40 VVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGalKGTPVAGCVDVPDNQF----GREAS-------------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 97 nLVPSLTAYENVALVTEVakspmrpadaLALVGLEERMHHF--PAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSK 174
Cdd:COG2401 102 -LIDAIGRKGDFKDAVEL----------LNAVGLSDAVLWLrrFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQ 170
|
170 180
....*....|....*....|....*
gi 1869873813 175 TGIRVIEALLGVNRQLGTTTVIITH 199
Cdd:COG2401 171 TAKRVARNLQKLARRAGITLVVATH 195
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
36-230 |
4.92e-20 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 85.28 E-value: 4.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 36 EVVVLLGPSGSGKTTLLNIMGGLdRPTSGSLFFRDLDLTELEDRELTKYR------RDHVGF--VFQFYNLvpsltAYEN 107
Cdd:COG4138 23 ELIHLIGPNGAGKSTLLARMAGL-LPGQGEILLNGRPLSDWSAAELARHRaylsqqQSPPFAmpVFQYLAL-----HQPA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 108 VALVTEVAKSPMRPADALALVGLEERMHHfpaQLSGGEQQRVAIARAIAK-------RPAVLLCDEPTGALDsktgIRVI 180
Cdd:COG4138 97 GASSEAVEQLLAQLAEALGLEDKLSRPLT---QLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLD----VAQQ 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 181 EALLGVNRQL---GTTTVIITH--NASIQGvADRVLFFADGR-IARVRTNEVRREA 230
Cdd:COG4138 170 AALDRLLRELcqqGITVVMSSHdlNHTLRH-ADRVWLLKQGKlVASGETAEVMTPE 224
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
25-220 |
6.28e-20 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 84.12 E-value: 6.28e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGGLD-RPTSGSLFFRDLDLTELEDREltkyR-RDHVGFVFQFYNLVPS 101
Cdd:cd03217 16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKtIMGHPKyEVTEGEILFKGEDITDLPPEE----RaRLGIFLAFQYPPEIPG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTayeNVALVTEVAKSpmrpadalalvgleermhhfpaqLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSkTGIRVIE 181
Cdd:cd03217 92 VK---NADFLRYVNEG-----------------------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDI-DALRLVA 144
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1869873813 182 ALLGVNRQLGTTTVIITHNASI--QGVADRVLFFADGRIAR 220
Cdd:cd03217 145 EVINKLREEGKSVLIITHYQRLldYIKPDRVHVLYDGRIVK 185
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
3-218 |
1.93e-19 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 82.70 E-value: 1.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPT---SGSLFFRDLDLTEledr 79
Cdd:cd03233 1 ASTLSWRNISFTTGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKE---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELTKYRRDHVgFVFQFYNLVPSLTAYENVALVtevakspmrpadalalvgLEERMHHFPAQLSGGEQQRVAIARAIAKRP 159
Cdd:cd03233 77 FAEKYPGEII-YVSEEDVHFPTLTVRETLDFA------------------LRCKGNEFVRGISGGERKRVSIAEALVSRA 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 160 AVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS--IQGVADRVLFFADGRI 218
Cdd:cd03233 138 SVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFVSLYQASdeIYDLFDKVLVLYEGRQ 198
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
20-219 |
1.96e-19 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 83.35 E-value: 1.96e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 20 VKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlteledreltkYRRDHVGFVFQF-YNL 98
Cdd:cd03220 33 GEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTV-----------------TVRGRVSSLLGLgGGF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLTAYENVALV--------TEVAKspmRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGA 170
Cdd:cd03220 96 NPELTGRENIYLNgrllglsrKEIDE---KIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAV 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 171 LDSKTGIRVIEALLGVNRQlGTTTVIITHN-ASIQGVADRVLFFADGRIA 219
Cdd:cd03220 173 GDAAFQEKCQRRLRELLKQ-GKTVILVSHDpSSIKRLCDRALVLEKGKIR 221
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
21-221 |
2.82e-19 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 86.06 E-value: 2.82e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDhVGFVFQ--FYNL 98
Cdd:PRK10261 336 EVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRD-IQFIFQdpYASL 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLTAYENVA--------LVTEVAKSpmRPADALALVGLE-ERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:PRK10261 415 DPRQTVGDSIMeplrvhglLPGKAAAA--RVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVS 492
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 170 ALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIARV 221
Cdd:PRK10261 493 ALDVSIRGQIINLLLDLQRDFGIAYLFISHDmAVVERISHRVAVMYLGQIVEI 545
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
9-217 |
3.15e-19 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 85.61 E-value: 3.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLdRPT---SGSLFFrdldlteleDRELTKYR 85
Cdd:NF040905 5 RGITKTF-PG---VKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV-YPHgsyEGEILF---------DGEVCRFK 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 --RD--HVGFVF--QFYNLVPSLTAYENVALVTEVAK--------SPMRPADALALVGLEERMHHFPAQLSGGEQQRVAI 151
Cdd:NF040905 71 diRDseALGIVIihQELALIPYLSIAENIFLGNERAKrgvidwneTNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEI 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 152 ARAIAKRPAVLLCDEPTGAL---DSktgirviEALLGVNRQL---GTTTVIITH--NaSIQGVADRVLFFADGR 217
Cdd:NF040905 151 AKALSKDVKLLILDEPTAALneeDS-------AALLDLLLELkaqGITSIIISHklN-EIRRVADSITVLRDGR 216
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
5-218 |
3.70e-19 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 85.50 E-value: 3.70e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 5 VFSAKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlteledreltky 84
Cdd:COG0488 315 VLELEGLSKSY--GDKTL--LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTV------------------ 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 85 RRDH---VGFVFQFY-NLVPSLTAYENVAlvtEVAKSpMRPADALALVGL----EERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:COG0488 373 KLGEtvkIGYFDQHQeELDPDKTVLDELR---DGAPG-GTEQEVRGYLGRflfsGDDAFKPVGVLSGGEKARLALAKLLL 448
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 157 KRPAVLLCDEPTGALDSKTgIRVIEALL----GvnrqlgtTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG0488 449 SPPNVLLLDEPTNHLDIET-LEALEEALddfpG-------TVLLVSHDrYFLDRVATRILEFEDGGV 507
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
25-200 |
4.25e-19 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 83.14 E-value: 4.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKyrrdHVGFVFQFYnLVPslta 104
Cdd:PRK11231 18 LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLAR----RLALLPQHH-LTP---- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 yENVALVTEVA--KSP-------MRPAD------ALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:PRK11231 89 -EGITVRELVAygRSPwlslwgrLSAEDnarvnqAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTT 167
|
170 180 190
....*....|....*....|....*....|.
gi 1869873813 170 ALDSKTGIRVIeALLGVNRQLGTTTVIITHN 200
Cdd:PRK11231 168 YLDINHQVELM-RLMRELNTQGKTVVTVLHD 197
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
18-218 |
6.88e-19 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 84.51 E-value: 6.88e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 18 GEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKyrrdHVGFVFQFYN 97
Cdd:PRK09536 14 GDTTV--LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASR----RVASVPQDTS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 LvpsltAYE-NVALVTEVAKSPMR----PADALALVGLEERMHH-----FPAQ----LSGGEQQRVAIARAIAKRPAVLL 163
Cdd:PRK09536 88 L-----SFEfDVRQVVEMGRTPHRsrfdTWTETDRAAVERAMERtgvaqFADRpvtsLSGGERQRVLLARALAQATPVLL 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 164 CDEPTGALDSKTGIRVIEallgVNRQL---GTTTVIITHNASIQG-VADRVLFFADGRI 218
Cdd:PRK09536 163 LDEPTASLDINHQVRTLE----LVRRLvddGKTAVAAIHDLDLAArYCDELVLLADGRV 217
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
25-211 |
7.94e-19 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 84.47 E-value: 7.94e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGL--------DRPTSGSLFF------------RDL-----DLTELEDR 79
Cdd:COG4178 379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLwpygsgriARPAGARVLFlpqrpylplgtlREAllypaTAEAFSDA 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELtkyrrdhvgfvfqfynlvpsltayenvalvtevakspmrpADALALVGLE---ERMH---HFPAQLSGGEQQRVAIAR 153
Cdd:COG4178 459 EL----------------------------------------REALEAVGLGhlaERLDeeaDWDQVLSLGEQQRLAFAR 498
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 154 AIAKRPAVLLCDEPTGALDSKTGIRVIEALLgvnRQLGTTTVI-ITHNASIQGVADRVL 211
Cdd:COG4178 499 LLLHKPDWLFLDEATSALDEENEAALYQLLR---EELPGTTVIsVGHRSTLAAFHDRVL 554
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
23-218 |
1.96e-18 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 83.34 E-value: 1.96e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNImggLDR---PTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNLV 99
Cdd:PRK11160 354 PVLKGLSLQIKAGEKVALLGRTGCGKSTLLQL---LTRawdPQQGEILLNGQPIADYSEAAL----RQAISVVSQRVHLF 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 pSLTAYENVALVTEVAkSPMRPADALALVGLEERMHHFPA----------QLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:PRK11160 427 -SATLRDNLLLAAPNA-SDEALIEVLQQVGLEKLLEDDKGlnawlgeggrQLSGGEQRRLGIARALLHDAPLLLLDEPTE 504
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 170 ALDSKTGIRVIEALLGVNRqlGTTTVIITHNAsiQGVA--DRVLFFADGRI 218
Cdd:PRK11160 505 GLDAETERQILELLAEHAQ--NKTVLMITHRL--TGLEqfDRICVMDNGQI 551
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
3-229 |
2.17e-18 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 83.15 E-value: 2.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTktyVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELt 82
Cdd:COG3845 255 EVVLEVENLS---VRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRER- 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 83 kyRRDHVGFV---FQFYNLVPSLTAYENVALvTEVAKSPM--------RPADALAlvglEERMHHF---------PA-QL 141
Cdd:COG3845 331 --RRLGVAYIpedRLGRGLVPDMSVAENLIL-GRYRRPPFsrggfldrKAIRAFA----EELIEEFdvrtpgpdtPArSL 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 142 SGGEQQRVAIARAIAKRPAVLLCDEPTGALDsktgIRVIEAllgVNRQL------GTTTVIIthnaS-----IQGVADRV 210
Cdd:COG3845 404 SGGNQQKVILARELSRDPKLLIAAQPTRGLD----VGAIEF---IHQRLlelrdaGAAVLLI----SedldeILALSDRI 472
|
250 260
....*....|....*....|
gi 1869873813 211 LFFADGRI-ARVRTNEVRRE 229
Cdd:COG3845 473 AVMYEGRIvGEVPAAEATRE 492
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
9-218 |
2.35e-18 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 80.90 E-value: 2.35e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRD-----LDLTeledreltk 83
Cdd:COG1134 26 ELLLRRRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGrvsalLELG--------- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 84 yrrdhVGFvfqfynlVPSLTAYENVALV--------TEVAKspmRPADALALVGLEERMHHfPAQ-LSGGEQQRVAIARA 154
Cdd:COG1134 97 -----AGF-------HPELTGRENIYLNgrllglsrKEIDE---KFDEIVEFAELGDFIDQ-PVKtYSSGMRARLAFAVA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 155 IAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHN-ASIQGVADRVLFFADGRI 218
Cdd:COG1134 161 TAVDPDILLVDEVLAVGDAAFQKKCLARIRELRES-GRTVIFVSHSmGAVRRLCDRAIWLEKGRL 224
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
9-217 |
2.65e-18 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 82.95 E-value: 2.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYvsGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLdRPT---SGSLFFrdlDLTELEDRELTKYR 85
Cdd:TIGR02633 5 KGIVKTF--GGVK--ALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHgtwDGEIYW---SGSPLKASNIRDTE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 86 RDHVGFVFQFYNLVPSLTAYENVALVTEVAKSPMRPADALALVGLEERMHHFP----------AQLSGGEQQRVAIARAI 155
Cdd:TIGR02633 77 RAGIVIIHQELTLVPELSVAENIFLGNEITLPGGRMAYNAMYLRAKNLLRELQldadnvtrpvGDYGGGQQQLVEIAKAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 156 AKRPAVLLCDEPTGALDSKTgirvIEALLGVNRQL---GTTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:TIGR02633 157 NKQARLLILDEPSSSLTEKE----TEILLDIIRDLkahGVACVYISHKLNeVKAVCDTICVIRDGQ 218
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
19-220 |
1.02e-17 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 79.75 E-value: 1.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 19 EVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrDLDLTELEDRELTKYRRDhVGFVFQFY-N 97
Cdd:PRK13642 17 ESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKV---KIDGELLTAENVWNLRRK-IGMVFQNPdN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 LVPSLTAYENVALVTEVAKSPM-----RPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:PRK13642 93 QFVGATVEDDVAFGMENQGIPReemikRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLD 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 173 SKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIAR 220
Cdd:PRK13642 173 PTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAASSDRILVMKAGEIIK 220
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
2-217 |
1.12e-17 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 81.44 E-value: 1.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 2 SEAVFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKT-TLLNIMGGLDRP----TSGSLFFRD-----L 71
Cdd:PRK10261 9 ARDVLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQAgglvQCDKMLLRRrsrqvI 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 72 DLTELEDRELTKYRRDHVGFVFQ--FYNLVPSLTAYENVALVT---------EVAKSPMRPADALALVGLEERMHHFPAQ 140
Cdd:PRK10261 89 ELSEQSAAQMRHVRGADMAMIFQepMTSLNPVFTVGEQIAESIrlhqgasreEAMVEAKRMLDQVRIPEAQTILSRYPHQ 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQG-VADRVLFFADGR 217
Cdd:PRK10261 169 LSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAeIADRVLVMYQGE 246
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
23-200 |
1.23e-17 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 81.29 E-value: 1.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTT----LLNIMggldrPTSGSLFFRDLDLTELEDRELTKYRRdHVGFVFQFYN- 97
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLHNLNRRQLLPVRH-RIQVVFQDPNs 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 -LVPSLTAYENVALVTEVAKSPMRPA-------DALALVGLE-ERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:PRK15134 374 sLNPRLNVLQIIEEGLRVHQPTLSAAqreqqviAVMEEVGLDpETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPT 453
|
170 180 190
....*....|....*....|....*....|..
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLGTTTVIITHN 200
Cdd:PRK15134 454 SSLDKTVQAQILALLKSLQQKHQLAYLFISHD 485
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-217 |
2.39e-17 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 80.36 E-value: 2.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVKvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLdRPT---SGSLFFrdlDLTELE 77
Cdd:PRK13549 1 MMEYLLEMKNITKTF--GGVK--ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV-YPHgtyEGEIIF---EGEELQ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 78 DRELTKYRRDHVGFVFQFYNLVPSLTAYENVALVTEVAKSPM--------RPADALALVGLEERMHHFPAQLSGGEQQRV 149
Cdd:PRK13549 73 ASNIRDTERAGIAIIHQELALVKELSVLENIFLGNEITPGGImdydamylRAQKLLAQLKLDINPATPVGNLGLGQQQLV 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 150 AIARAIAKRPAVLLCDEPTGAL-DSKTGIrvieaLLGVNRQL---GTTTVIITHNAS-IQGVADRVLFFADGR 217
Cdd:PRK13549 153 EIAKALNKQARLLILDEPTASLtESETAV-----LLDIIRDLkahGIACIYISHKLNeVKAISDTICVIRDGR 220
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
4-200 |
2.60e-17 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 78.01 E-value: 2.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 4 AVFSAKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreLTK 83
Cdd:PRK10895 2 ATLTAKNLAKAYKGRRV----VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLP---LHA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 84 YRRDHVGFVFQFYNLVPSLTAYENVALVTEVAKSPMRPADALALVGLEERMH------HFPAQLSGGEQQRVAIARAIAK 157
Cdd:PRK10895 75 RARRGIGYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHiehlrdSMGQSLSGGERRRVEIARALAA 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1869873813 158 RPAVLLCDEPTGALDSKTGI---RVIEALlgvnRQLGTTTVIITHN 200
Cdd:PRK10895 155 NPKFILLDEPFAGVDPISVIdikRIIEHL----RDSGLGVLITDHN 196
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
31-229 |
2.86e-17 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 78.05 E-value: 2.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 31 EITEKEVVVLLGPSGSGKTTLLNIMGGLdRPTSGSLFFRDLDLTELEDRELTKYR-----RDHVGF---VFQFYNL-VPS 101
Cdd:PRK03695 18 EVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQPLEAWSAAELARHRaylsqQQTPPFampVFQYLTLhQPD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTA-YENVALVTEVAkspmrpadalALVGLEERMHHFPAQLSGGEQQRVAIA-------RAIAKRPAVLLCDEPTGALD- 172
Cdd:PRK03695 97 KTRtEAVASALNEVA----------EALGLDDKLGRSVNQLSGGEWQRVRLAavvlqvwPDINPAGQLLLLDEPMNSLDv 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 173 SKTGI--RVIEALLgvnrQLGTTTVIITH--NASIQGvADRVLFFADGR-IARVRTNEVRRE 229
Cdd:PRK03695 167 AQQAAldRLLSELC----QQGIAVVMSSHdlNHTLRH-ADRVWLLKQGKlLASGRRDEVLTP 223
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
7-235 |
3.16e-17 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 78.61 E-value: 3.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 7 SAKALTKTYvsGEVkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFrdldltelEDRELTKYRR 86
Cdd:COG4152 3 ELKGLTKRF--GDK--TAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLW--------DGEPLDPEDR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 87 DHVGfvfqfY-----NLVPSLTAYENVA----LvtevaKSpMRPADA-------LALVGLEERMHHFPAQLSGGEQQRVA 150
Cdd:COG4152 71 RRIG-----YlpeerGLYPKMKVGEQLVylarL-----KG-LSKAEAkrradewLERLGLGDRANKKVEELSKGNQQKVQ 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 151 IARAIAKRPAVLLCDEPTGALDSktgIRViEALLGVNRQL---GTTTVIITHN-ASIQGVADRVLFFADGR-IARVRTNE 225
Cdd:COG4152 140 LIAALLHDPELLILDEPFSGLDP---VNV-ELLKDVIRELaakGTTVIFSSHQmELVEELCDRIVIINKGRkVLSGSVDE 215
|
250
....*....|
gi 1869873813 226 VRREAAELTW 235
Cdd:COG4152 216 IRRQFGRNTL 225
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
25-217 |
3.17e-17 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 79.92 E-value: 3.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGldRPTSGSLFFRDLdlteLEDRELTKYRRDHVGFVFQFYNLVPSLTA 104
Cdd:PLN03211 84 LNGVTGMASPGEILAVLGPSGSGKSTLLNALAG--RIQGNNFTGTIL----ANNRKPTKQILKRTGFVTQDDILYPHLTV 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVT--EVAKS-----PMRPADA----LALVGLEERM--HHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PLN03211 158 RETLVFCSllRLPKSltkqeKILVAESviseLGLTKCENTIigNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGL 237
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 172 DSKTGIRVIEALLGVnRQLGTTTVIITHNAS--IQGVADRVLFFADGR 217
Cdd:PLN03211 238 DATAAYRLVLTLGSL-AQKGKTIVTSMHQPSsrVYQMFDSVLVLSEGR 284
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
25-211 |
4.39e-17 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 75.65 E-value: 4.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlteledrelTKYRRDHVGFVfqfynlvpslta 104
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRI---------------GMPEGEDLLFL------------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 yenvalvtevaksPMRP-------ADALAlvgleermhhFP--AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:cd03223 70 -------------PQRPylplgtlREQLI----------YPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEES 126
|
170 180 190
....*....|....*....|....*....|....*.
gi 1869873813 176 GIRVIEALlgvnRQLGTTTVIITHNASIQGVADRVL 211
Cdd:cd03223 127 EDRLYQLL----KELGITVISVGHRPSLWKFHDRVL 158
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
24-218 |
5.95e-17 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 79.29 E-value: 5.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdLDLTELEDRELTKYRrDHVGFVFQ----FYNLV 99
Cdd:PRK11176 358 ALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEIL---LDGHDLRDYTLASLR-NQVALVSQnvhlFNDTI 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 PSLTAY--ENVALVTEVAKSPmRPADALALV-----GLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:PRK11176 434 ANNIAYarTEQYSREQIEEAA-RMAYAMDFInkmdnGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALD 512
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 173 SKTGIRVIEAL--LGVNRqlgtTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK11176 513 TESERAIQAALdeLQKNR----TSLVIAHRLSTIEKADEILVVEDGEI 556
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-199 |
6.84e-17 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 77.92 E-value: 6.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvsGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELedre 80
Cdd:PRK13537 3 MSVAPIDFRNVEKRY--GDKLV--VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSR---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 lTKYRRDHVGFVFQFYNLVPSLTAYENVALVTE-----VAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAI 155
Cdd:PRK13537 75 -ARHARQRVGVVPQFDNLDPDFTVRENLLVFGRyfglsAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARAL 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 156 AKRPAVLLCDEPTGALDSKTGIRVIEALlgvnRQL---GTTTVIITH 199
Cdd:PRK13537 154 VNDPDVLVLDEPTTGLDPQARHLMWERL----RSLlarGKTILLTTH 196
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
25-218 |
1.45e-16 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 76.58 E-value: 1.45e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLtELEDRELTKYRRdHVGFVFQ------FYNL 98
Cdd:PRK13638 17 LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPL-DYSKRGLLALRQ-QVATVFQdpeqqiFYTD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLTAYENVALVTEVAKSPMRPADALALVGlEERMHHFPAQ-LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:PRK13638 95 IDSDIAFSLRNLGVPEAEITRRVDEALTLVD-AQHFRHQPIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRT 173
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1869873813 178 RVIEALLGVNRQlGTTTVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:PRK13638 174 QMIAIIRRIVAQ-GNHVIISSHDIDlIYEISDAVYVLRQGQI 214
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
25-199 |
2.95e-16 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 74.45 E-value: 2.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDreltKYRRDhVGFVFQFYNLVPSLTA 104
Cdd:cd03231 16 FSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRD----SIARG-LLYLGHAPGIKTTLSV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEVAkSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDsKTGIRVIEALL 184
Cdd:cd03231 91 LENLRFWHADH-SDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALD-KAGVARFAEAM 168
|
170
....*....|....*
gi 1869873813 185 GVNRQLGTTTVIITH 199
Cdd:cd03231 169 AGHCARGGMVVLTTH 183
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
3-226 |
3.44e-16 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 75.21 E-value: 3.44e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKT--YVSGEVK---VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdldlteLE 77
Cdd:PRK15112 2 ETLLEVRNLSKTfrYRTGWFRrqtVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELL--------ID 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 78 DRELT----KYRRDHVGFVFQfyNLVPSLTAYENVA--------LVTEVAKSPMRPA--DALALVGL-EERMHHFPAQLS 142
Cdd:PRK15112 74 DHPLHfgdySYRSQRIRMIFQ--DPSTSLNPRQRISqildfplrLNTDLEPEQREKQiiETLRQVGLlPDHASYYPHMLA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 143 GGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIIT-HNASIQGVADRVLFFADGRIA-R 220
Cdd:PRK15112 152 PGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTqHLGMMKHISDQVLVMHQGEVVeR 231
|
....*.
gi 1869873813 221 VRTNEV 226
Cdd:PRK15112 232 GSTADV 237
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
2-200 |
3.91e-16 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 75.21 E-value: 3.91e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 2 SEAVFSAKALTKTyVSGEVKVHALNevdLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREL 81
Cdd:PRK10575 8 SDTTFALRNVSFR-VPGRTLLHPLS---LTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 82 TKyrrdHVGFVFQFYNLVPSLTAYENVAlvteVAKSPMRPA-------------DALALVGLEERMHHFPAQLSGGEQQR 148
Cdd:PRK10575 84 AR----KVAYLPQQLPAAEGMTVRELVA----IGRYPWHGAlgrfgaadrekveEAISLVGLKPLAHRLVDSLSGGERQR 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 149 VAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN 200
Cdd:PRK10575 156 AWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHD 207
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
31-216 |
4.07e-16 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 74.75 E-value: 4.07e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 31 EITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSlffrdldltELEDRELTKYR-----RDHVGFVFQF-YNLVPSLta 104
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGD---------IEIELDTVSYKpqyikADYEGTVRDLlSSITKDF-- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEVAKsPMrpadalalvGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALL 184
Cdd:cd03237 90 YTHPYFKTEIAK-PL---------QIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIR 159
|
170 180 190
....*....|....*....|....*....|...
gi 1869873813 185 GVNRQLGTTTVIITHN-ASIQGVADRVLFFaDG 216
Cdd:cd03237 160 RFAENNEKTAFVVEHDiIMIDYLADRLIVF-EG 191
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
25-218 |
4.25e-16 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 76.68 E-value: 4.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQfYNLVPSLTA 104
Cdd:PRK10790 357 LQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVL----RQGVAMVQQ-DPVVLADTF 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEVakSPMRPADALALVGLEERMHHFPA-----------QLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDS 173
Cdd:PRK10790 432 LANVTLGRDI--SEEQVWQALETVQLAELARSLPDglytplgeqgnNLSVGQKQLLALARVLVQTPQILILDEATANIDS 509
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 174 KTGIRVIEALLGVNRQlgTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PRK10790 510 GTEQAIQQALAAVREH--TTLVVIAHRLSTIVEADTILVLHRGQA 552
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
1-200 |
5.29e-16 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 74.92 E-value: 5.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVkvhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE 80
Cdd:PRK15056 2 MQQAGIVVNDVTVTWRNGHT---ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYRRDHVGFVFQFYNLVPSLTA---YENVALVTEV-AKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIA 156
Cdd:PRK15056 79 LVAYVPQSEEVDWSFPVLVEDVVMmgrYGHMGWLRRAkKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIA 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 157 KRPAVLLCDEPTGALDSKTGIRVIeALLGVNRQLGTTTVIITHN 200
Cdd:PRK15056 159 QQGQVILLDEPFTGVDVKTEARII-SLLRELRDEGKTMLVSTHN 201
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
22-216 |
8.02e-16 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 75.81 E-value: 8.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldltELEDRELT-KYRRDH----VGFVFQFY 96
Cdd:PRK10762 17 VKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSI--------LYLGKEVTfNGPKSSqeagIGIIHQEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 97 NLVPSLTAYENVALVTEVA--------KSPMRPADAL-ALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEP 167
Cdd:PRK10762 89 NLIPQLTIAENIFLGREFVnrfgridwKKMYAEADKLlARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEP 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 168 TGAL-DSKTgirviEALLGVNRQL---GTTTVIITHN-ASIQGVADRVLFFADG 216
Cdd:PRK10762 169 TDALtDTET-----ESLFRVIRELksqGRGIVYISHRlKEIFEICDDVTVFRDG 217
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
10-200 |
1.11e-15 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 73.61 E-value: 1.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 10 ALTKTYVS-GEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlteledreltkyRRDH 88
Cdd:PRK09544 6 SLENVSVSfGQRRV--LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI------------------KRNG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 ---VGFVFQFYNLVPS--LTAYENVALVTEVAKSPMRPAdaLALVGlEERMHHFPAQ-LSGGEQQRVAIARAIAKRPAVL 162
Cdd:PRK09544 66 klrIGYVPQKLYLDTTlpLTVNRFLRLRPGTKKEDILPA--LKRVQ-AGHLIDAPMQkLSGGETQRVLLARALLNRPQLL 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 1869873813 163 LCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN 200
Cdd:PRK09544 143 VLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHD 180
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
25-201 |
1.24e-15 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 72.96 E-value: 1.24e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrDLDLTELEDREltkyRRDHVGFVFQFYNLVPSLTA 104
Cdd:PRK13543 27 FGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQI---QIDGKTATRGD----RSRFMAYLGHLPGLKADLST 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEV-AKSPMR-PADALALVGLEERMHHFPAQLSGGEQQRVAIARaIAKRPAVL-LCDEPTGALDSKtGIRVIE 181
Cdd:PRK13543 100 LENLHFLCGLhGRRAKQmPGSALAIVGLAGYEDTLVRQLSAGQKKRLALAR-LWLSPAPLwLLDEPYANLDLE-GITLVN 177
|
170 180
....*....|....*....|
gi 1869873813 182 ALLGVNRQLGTTTVIITHNA 201
Cdd:PRK13543 178 RMISAHLRGGGAALVTTHGA 197
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
22-223 |
2.52e-15 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 74.18 E-value: 2.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdLDLTELEDRELTKYRRDHVGFVFQFYNLVPS 101
Cdd:PRK11288 17 VKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSIL---IDGQEMRFASTTAALAAGVAIIYQELHLVPE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVAL--------VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDS 173
Cdd:PRK11288 94 MTVAENLYLgqlphkggIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSA 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 174 ktgiRVIEALLGVNRQL---GTTTVIITHN-ASIQGVADRVLFFADGRiaRVRT 223
Cdd:PRK11288 174 ----REIEQLFRVIRELraeGRVILYVSHRmEEIFALCDAITVFKDGR--YVAT 221
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
3-231 |
4.57e-15 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 73.51 E-value: 4.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTyvsgevkvHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTEL------ 76
Cdd:COG1129 254 EVVLEVEGLSVG--------GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRsprdai 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 77 --------EDReltkyRRDhvGfvfqfynLVPSLTAYENVALVT----------------EVAKSPM-----RPADALAL 127
Cdd:COG1129 326 ragiayvpEDR-----KGE--G-------LVLDLSIRENITLASldrlsrgglldrrrerALAEEYIkrlriKTPSPEQP 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 128 VGleermhhfpaQLSGGEQQRVAIARAIAKRPAVLLCDEPT-----GAldsKTGI-RVIEALlgvNRQlGTTTVIIThna 201
Cdd:COG1129 392 VG----------NLSGGNQQKVVLAKWLATDPKVLILDEPTrgidvGA---KAEIyRLIREL---AAE-GKAVIVIS--- 451
|
250 260 270
....*....|....*....|....*....|....
gi 1869873813 202 S----IQGVADRVLFFADGRIARvrtnEVRREAA 231
Cdd:COG1129 452 SelpeLLGLSDRILVMREGRIVG----ELDREEA 481
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
15-216 |
7.04e-15 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 70.04 E-value: 7.04e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 15 YVSGeVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGgldrPTSGSLFFRDLdlteledreLTKYRRDHVGFVFQ 94
Cdd:cd03238 2 TVSG-ANVHNLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGL----YASGKARLISF---------LPKFSRNKLIFIDQ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 95 FYNLVpsltayenvalvtevakspmrpADALALVGLEERMhhfpAQLSGGEQQRVAIARAIAKRP--AVLLCDEPTGALD 172
Cdd:cd03238 68 LQFLI----------------------DVGLGYLTLGQKL----STLSGGELQRVKLASELFSEPpgTLFILDEPSTGLH 121
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 173 SKTGIRVIEALLGVnRQLGTTTVIITHNASIQGVADRVLFFADG 216
Cdd:cd03238 122 QQDINQLLEVIKGL-IDLGNTVILIEHNLDVLSSADWIIDFGPG 164
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-199 |
7.60e-15 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 72.56 E-value: 7.60e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYvSGEVKVhalNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrdldlTELEDRE 80
Cdd:PRK13536 37 MSTVAIDLAGVSKSY-GDKAVV---NGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKI-------TVLGVPV 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYR--RDHVGFVFQFYNLVPSLTAYENVALVTEVAKSPMRPADA-----LALVGLEERMHHFPAQLSGGEQQRVAIAR 153
Cdd:PRK13536 106 PARARlaRARIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAvipslLEFARLESKADARVSDLSGGMKRRLTLAR 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 154 AIAKRPAVLLCDEPTGALDSKTGIRVIEALlgvnRQL---GTTTVIITH 199
Cdd:PRK13536 186 ALINDPQLLILDEPTTGLDPHARHLIWERL----RSLlarGKTILLTTH 230
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
28-226 |
2.39e-14 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 70.11 E-value: 2.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 28 VDLEITEKEVVVLLGPSGSGKTtlLNIMGGLD------RPTSGSLFfrdLDLTELEDRELtkyRRDHVGFVFQ----FYN 97
Cdd:PRK10418 22 VSLTLQRGRVLALVGGSGSGKS--LTCAAALGilpagvRQTAGRVL---LDGKPVAPCAL---RGRKIATIMQnprsAFN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 LVPSLTAYenvalVTEVAKSPMRPAD------ALALVGLEER---MHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:PRK10418 94 PLHTMHTH-----ARETCLALGKPADdatltaALEAVGLENAarvLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPT 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 169 GALDSKTGIRVIEALLGVNRQLGTTTVIITHNasiQGV----ADRVLFFADGRIarVRTNEV 226
Cdd:PRK10418 169 TDLDVVAQARILDLLESIVQKRALGMLLVTHD---MGVvarlADDVAVMSHGRI--VEQGDV 225
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
25-199 |
3.18e-14 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 68.82 E-value: 3.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLteleDRELTKYRRdHVGFVFQFYNLVPSLTA 104
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCTYQK-QLCFVGHRSGINPYLTL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTgIRVIEALL 184
Cdd:PRK13540 92 RENCLYDIHFSPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELS-LLTIITKI 170
|
170
....*....|....*
gi 1869873813 185 GVNRQLGTTTVIITH 199
Cdd:PRK13540 171 QEHRAKGGAVLLTSH 185
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
1-213 |
1.18e-13 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 69.43 E-value: 1.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKVHALnevdlEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLffrDLDLT------ 74
Cdd:COG1245 337 EEETLVEYPDLTKSYGGFSLEVEGG-----EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEV---DEDLKisykpq 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 75 ELE-DRELTkyrrdhvgfVFQF-YNLVPSltAYENVALVTEVAKsPMrpadalalvGLEERMHHFPAQLSGGEQQRVAIA 152
Cdd:COG1245 409 YISpDYDGT---------VEEFlRSANTD--DFGSSYYKTEIIK-PL---------GLEKLLDKNVKDLSGGELQRVAIA 467
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 153 RAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFF 213
Cdd:COG1245 468 ACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDHDiYLIDYISDRLMVF 529
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
24-218 |
1.42e-13 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 69.66 E-value: 1.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDL-TELEdreltkYRRDHVGFVFQFYNLVPSL 102
Cdd:TIGR01257 945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIeTNLD------AVRQSLGMCPQHNILFHHL 1018
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYENVALVTEVAKSPMRPAD-----ALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGI 177
Cdd:TIGR01257 1019 TVAEHILFYAQLKGRSWEEAQlemeaMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRR 1098
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 178 RVIEALLgvNRQLGTTTVIITHN---ASIQGvaDRVLFFADGRI 218
Cdd:TIGR01257 1099 SIWDLLL--KYRSGRTIIMSTHHmdeADLLG--DRIAIISQGRL 1138
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
1-200 |
2.02e-13 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 67.70 E-value: 2.02e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVKV-HALNevdLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDR 79
Cdd:PRK10253 1 MTESVARLRGEQLTLGYGKYTVaENLT---VEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 80 ELTkyRRdhVGFVFQFYNLVPSLTAYENVALvtevAKSPMRP---------ADALALVGLEERMHHFPAQ----LSGGEQ 146
Cdd:PRK10253 78 EVA--RR--IGLLAQNATTPGDITVQELVAR----GRYPHQPlftrwrkedEEAVTKAMQATGITHLADQsvdtLSGGQR 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 147 QRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN 200
Cdd:PRK10253 150 QRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHD 203
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
5-216 |
3.25e-13 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 65.73 E-value: 3.25e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 5 VFSAKALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGldRPTSGSlffRDLDLTeLEDRELTKY 84
Cdd:cd03232 3 VLTWKNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAG--RKTAGV---ITGEIL-INGRPLDKN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 85 RRDHVGFVFQFYNLVPSLTAYEnvalvtevaksPMRPADALALVGLEERmhhfpaqlsggeqQRVAIARAIAKRPAVLLC 164
Cdd:cd03232 77 FQRSTGYVEQQDVHSPNLTVRE-----------ALRFSALLRGLSVEQR-------------KRLTIGVELAAKPSILFL 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 165 DEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITH--NASIQGVADRVLFFADG 216
Cdd:cd03232 133 DEPTSGLDSQAAYNIVRFLKKLADS-GQAILCTIHqpSASIFEKFDRLLLLKRG 185
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
5-219 |
3.95e-13 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 67.77 E-value: 3.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 5 VFSAKALTKTYvSGevkVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFF---RDLDLTELEDREL 81
Cdd:PRK15439 11 LLCARSISKQY-SG---VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIggnPCARLTPAKAHQL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 82 TKYrrdhvgFVFQFYNLVPSLTAYENVAL-VTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPA 160
Cdd:PRK15439 87 GIY------LVPQEPLLFPNLSVKENILFgLPKRQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 161 VLLCDEPTGAL---DSKTGIRVIEALLgvnrQLGTTTVIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:PRK15439 161 ILILDEPTASLtpaETERLFSRIRELL----AQGVGIVFISHKLPeIRQLADRISVMRDGTIA 219
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
24-219 |
6.78e-13 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 65.59 E-value: 6.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQ----F---- 95
Cdd:cd03244 19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL----RSRISIIPQdpvlFsgti 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 -YNLVPsLTAYENVALVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSK 174
Cdd:cd03244 95 rSNLDP-FGEYSDEELWQALERVGLKEFVESLPGGLDTVVEEGGENLSVGQRQLLCLARALLRKSKILVLDEATASVDPE 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 175 TGiRVIEALLGVNRQlGTTTVIITHNasIQGVA--DRVLFFADGRIA 219
Cdd:cd03244 174 TD-ALIQKTIREAFK-DCTVLTIAHR--LDTIIdsDRILVLDKGRVV 216
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
10-213 |
8.00e-13 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 67.14 E-value: 8.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 10 ALTKTYVSGEVKVHALnevdlEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFrDLDLTeledreltkY----- 84
Cdd:PRK13409 345 DLTKKLGDFSLEVEGG-----EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDP-ELKIS---------Ykpqyi 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 85 RRDHVGFVFQFYNLVPSltAYENVALVTEVAKsPMrpadalalvGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLC 164
Cdd:PRK13409 410 KPDYDGTVEDLLRSITD--DLGSSYYKSEIIK-PL---------QLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLL 477
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1869873813 165 DEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFF 213
Cdd:PRK13409 478 DEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDHDiYMIDYISDRLMVF 527
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
25-219 |
1.05e-12 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 67.11 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLnimggldrptsGSLffrdldLTELEDRELTKYRRDHVGFVFQfYNLVPSLTA 104
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLL-----------QSL------LSQFEISEGRVWAERSIAYVPQ-QAWIMNATV 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEvaKSPMRPADALALVGLEERMHHFPA-----------QLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDS 173
Cdd:PTZ00243 738 RGNILFFDE--EDAARLADAVRVSQLEADLAQLGGgleteigekgvNLSGGQKARVSLARAVYANRDVYLLDDPLSALDA 815
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1869873813 174 KTGIRVIEALLgVNRQLGTTTVIITHNASIQGVADRVLFFADGRIA 219
Cdd:PTZ00243 816 HVGERVVEECF-LGALAGKTRVLATHQVHVVPRADYVVALGDGRVE 860
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
24-231 |
2.82e-12 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 65.38 E-value: 2.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdLDLTELEDRELTKYRRdHVGFVFQFYNLVPSLT 103
Cdd:PRK10522 338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEIL---LDGKPVTAEQPEDYRK-LFSAVFTDFHLFDQLL 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENvalvteVAKSPMRPADALALVGLEERMHH-----FPAQLSGGEQQRVAIARAIAKRPAVLLCDEptGALDSKTGIR 178
Cdd:PRK10522 414 GPEG------KPANPALVEKWLERLKMAHKLELedgriSNLKLSKGQKKRLALLLALAEERDILLLDE--WAADQDPHFR 485
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 179 VI--EALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIARVrTNEVRREAA 231
Cdd:PRK10522 486 REfyQVLLPLLQEMGKTIFAISHDDHYFIHADRLLEMRNGQLSEL-TGEERDAAS 539
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
40-199 |
4.26e-12 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 64.96 E-value: 4.26e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 40 LLGPSGSGKTTLLNIMGGLDRPTSGslffrdldltelEDRELTKYRrdhVGFVFQFYNLVPSLTAYENVAL-VTEVAKSP 118
Cdd:TIGR03719 36 VLGLNGAGKSTLLRIMAGVDKDFNG------------EARPQPGIK---VGYLPQEPQLDPTKTVRENVEEgVAEIKDAL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 119 MR-----------PADALALVG----LEERMHHFPA------------------------QLSGGEQQRVAIARAIAKRP 159
Cdd:TIGR03719 101 DRfneisakyaepDADFDKLAAeqaeLQEIIDAADAwdldsqleiamdalrcppwdadvtKLSGGERRRVALCRLLLSKP 180
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1869873813 160 AVLLCDEPTGALDSKTgIRVIEALLgvnRQLGTTTVIITH 199
Cdd:TIGR03719 181 DMLLLDEPTNHLDAES-VAWLERHL---QEYPGTVVAVTH 216
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
40-172 |
8.78e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 63.98 E-value: 8.78e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 40 LLGPSGSGKTTLLNIMGGLDRPTSGslffrdldltelEDRELTKYRrdhVGFVFQFYNLVPSLTAYENVAL-VTEVAK-- 116
Cdd:PRK11819 38 VLGLNGAGKSTLLRIMAGVDKEFEG------------EARPAPGIK---VGYLPQEPQLDPEKTVRENVEEgVAEVKAal 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 117 -----------SPMRPADALA--LVGLEERMHHFPA------------------------QLSGGEQQRVAIARAIAKRP 159
Cdd:PRK11819 103 drfneiyaayaEPDADFDALAaeQGELQEIIDAADAwdldsqleiamdalrcppwdakvtKLSGGERRRVALCRLLLEKP 182
|
170
....*....|...
gi 1869873813 160 AVLLCDEPTGALD 172
Cdd:PRK11819 183 DMLLLDEPTNHLD 195
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
25-219 |
1.01e-11 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 64.20 E-value: 1.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMggldrptsgslffrdldLTELEDRELTKYRRDHVGFVFQfYNLVPSLTA 104
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSAL-----------------LAEMDKVEGHVHMKGSVAYVPQ-QAWIQNDSL 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENV----ALVTEVAKSPMrpaDALALV--------GLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:TIGR00957 716 RENIlfgkALNEKYYQQVL---EACALLpdleilpsGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVD 792
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 173 SKTGIRVIEALLGVNRQL-GTTTVIITHNASIQGVADRVLFFADGRIA 219
Cdd:TIGR00957 793 AHVGKHIFEHVIGPEGVLkNKTRILVTHGISYLPQVDVIIVMSGGKIS 840
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
25-218 |
1.19e-11 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 62.54 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGlDRPTS---------GSLFFRDLDLTELEDRELTKYR-----RDHVG 90
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG-DLTGGgaprgarvtGDVTLNGEPLAAIDAPRLARLRavlpqAAQPA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNLVpSLTAYENVALVTEVAKSPMRPAD-ALALVGLEERMHHFPAQLSGGEQQRVAIARAIAK---------RPA 160
Cdd:PRK13547 96 FAFSAREIV-LLGRYPHARRAGALTHRDGEIAWqALALAGATALVGRDVTTLSGGELARVQFARVLAQlwpphdaaqPPR 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 161 VLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGV-ADRVLFFADGRI 218
Cdd:PRK13547 175 YLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARhADRIAMLADGAI 233
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
24-168 |
1.26e-11 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 63.61 E-value: 1.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGS--LFFRDLDLTELEDReltkyRRdhVGFVFQFYNLVPS 101
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEawLFGQPVDAGDIATR-----RR--VGYMSQAFSLYGE 353
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 102 LTAYENVAL------VTEvAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:NF033858 354 LTVRQNLELharlfhLPA-AEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPT 425
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
27-219 |
2.41e-11 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 62.76 E-value: 2.41e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 27 EVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDREltkyrRDHVGFVF-----QFYNLVPS 101
Cdd:PRK15439 281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQ-----RLARGLVYlpedrQSSGLYLD 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVALVTEVAKSP-MRPADALALVgleERMHHF----------PAQ-LSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:PRK15439 356 APLAWNVCALTHNRRGFwIKPARENAVL---ERYRRAlnikfnhaeqAARtLSGGNQQKVLIAKCLEASPQLLIVDEPTR 432
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 170 ALDskTGIRV-IEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGRIA 219
Cdd:PRK15439 433 GVD--VSARNdIYQLIRSIAAQNVAVLFISSDlEEIEQMADRVLVMHQGEIS 482
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
25-211 |
2.65e-11 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 62.66 E-value: 2.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGG---LDrptSGSLFF-RDLDLTELEDREltkyRRDHVGFVFQFY---- 96
Cdd:PRK11147 19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILNGevlLD---DGRIIYeQDLIVARLQQDP----PRNVEGTVYDFVaegi 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 97 -NLVPSLTAYEnvALVTEVAKSPM------------------------RPADALALVGLEERMHHfpAQLSGGEQQRVAI 151
Cdd:PRK11147 92 eEQAEYLKRYH--DISHLVETDPSeknlnelaklqeqldhhnlwqlenRINEVLAQLGLDPDAAL--SSLSGGWLRKAAL 167
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 152 ARAIAKRPAVLLCDEPTGALDsktgIRVIEALLGVNRQLGTTTVIITHNAS-IQGVADRVL 211
Cdd:PRK11147 168 GRALVSNPDVLLLDEPTNHLD----IETIEWLEGFLKTFQGSIIFISHDRSfIRNMATRIV 224
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
3-232 |
3.58e-11 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 62.11 E-value: 3.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKtYVSGEVKvhalnEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRE-- 80
Cdd:PRK09700 263 ETVFEVRNVTS-RDRKKVR-----DISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDav 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 ------LTKYRRDHvGFVfqfynlvPSLTAYENVALVTEVAKSPMRPADALalvgLEERMHHFPAQ-------------- 140
Cdd:PRK09700 337 kkgmayITESRRDN-GFF-------PNFSIAQNMAISRSLKDGGYKGAMGL----FHEVDEQRTAEnqrellalkchsvn 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 -----LSGGEQQRVAIARAIAKRPAVLLCDEPTGALD--SKTGIrviealLGVNRQLGTTTVIITHNAS----IQGVADR 209
Cdd:PRK09700 405 qniteLSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDvgAKAEI------YKVMRQLADDGKVILMVSSelpeIITVCDR 478
|
250 260
....*....|....*....|...
gi 1869873813 210 VLFFADGRIARVRTNevRREAAE 232
Cdd:PRK09700 479 IAVFCEGRLTQILTN--RDDMSE 499
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
21-210 |
7.23e-11 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 59.96 E-value: 7.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTL----LNIMGGLDRPTSGSLFFR---------DLDLTE-------LEDRE 80
Cdd:cd03270 7 REHNLKNVDVDIPRNKLVVITGVSGSGKSSLafdtIYAEGQRRYVESLSAYARqflgqmdkpDVDSIEglspaiaIDQKT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 81 LTKYRRDHVGFVFQFYNLVPSLtaYENVALVTEVakspmrpaDALALVGLEE-RMHHFPAQLSGGEQQRVAIARAI-AKR 158
Cdd:cd03270 87 TSRNPRSTVGTVTEIYDYLRLL--FARVGIRERL--------GFLVDVGLGYlTLSRSAPTLSGGEAQRIRLATQIgSGL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 159 PAVL-LCDEPTGALDSKTGIRVIEALLGVnRQLGTTTVIITHNASIQGVADRV 210
Cdd:cd03270 157 TGVLyVLDEPSIGLHPRDNDRLIETLKRL-RDLGNTVLVVEHDEDTIRAADHV 208
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
37-219 |
8.28e-11 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 61.10 E-value: 8.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 37 VVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDldlteledreltkyrRDHVGFVFQFY-NLVPSLTAYENVALVTEVA 115
Cdd:TIGR03719 350 IVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGE---------------TVKLAYVDQSRdALDPNKTVWEEISGGLDII 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 116 KSPMRPADALALVGL--------EERMhhfpAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTgIRVIE-ALLgv 186
Cdd:TIGR03719 415 KLGKREIPSRAYVGRfnfkgsdqQKKV----GQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDLDVET-LRALEeALL-- 487
|
170 180 190
....*....|....*....|....*....|...
gi 1869873813 187 nrQLGTTTVIITHnasiqgvaDRvlFFADgRIA 219
Cdd:TIGR03719 488 --NFAGCAVVISH--------DR--WFLD-RIA 507
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
24-219 |
9.81e-11 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 60.88 E-value: 9.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLnimggldrptsgSLFFRDLDLTE----LEDRELTKYRRDHVGFVFQFYNLV 99
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLL------------SLIQRHFDVSEgdirFHDIPLTKLQLDSWRSRLAVVSQT 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 100 PSL---TAYENVAL---------VTEVAKSPMRPADALAL-VGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:PRK10789 398 PFLfsdTVANNIALgrpdatqqeIEHVARLASVHDDILRLpQGYDTEVGERGVMLSGGQKQRISIARALLLNAEILILDD 477
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1869873813 167 PTGALDSKTGIRVIEALlgvnRQLGTT-TVIIT-HNASIQGVADRVLFFADGRIA 219
Cdd:PRK10789 478 ALSAVDGRTEHQILHNL----RQWGEGrTVIISaHRLSALTEASEILVMQHGHIA 528
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
25-218 |
1.62e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 60.37 E-value: 1.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGldrptsgslffrdlDLTELEDRELTKyrRDHVGFVFQFyNLVPSLTA 104
Cdd:PLN03232 633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLG--------------ELSHAETSSVVI--RGSVAYVPQV-SWIFNATV 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 105 YENVALVTEVakSPMRPADALALVGLEERMHHFPAQ-----------LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDS 173
Cdd:PLN03232 696 RENILFGSDF--ESERYWRAIDVTALQHDLDLLPGRdlteigergvnISGGQKQRVSMARAVYSNSDIYIFDDPLSALDA 773
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 174 KTGIRVIEALLGVNRQlGTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PLN03232 774 HVAHQVFDSCMKDELK-GKTRVLVTNQLHFLPLMDRIILVSEGMI 817
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
20-218 |
2.60e-10 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 59.74 E-value: 2.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 20 VKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMG----GLDRPTSGSLFFRDLDLTELEdreltKYRRDHVGFVFQF 95
Cdd:TIGR00956 72 KTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDGITPEEIK-----KHYRGDVVYNAET 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 96 YNLVPSLTAYENvaLVTeVAKspMR-PADALALVGLEERMHH----------------------FPAQLSGGEQQRVAIA 152
Cdd:TIGR00956 147 DVHFPHLTVGET--LDF-AAR--CKtPQNRPDGVSREEYAKHiadvymatyglshtrntkvgndFVRGVSGGERKRVSIA 221
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 153 RAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNAS--IQGVADRVLFFADGRI 218
Cdd:TIGR00956 222 EASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSqdAYELFDKVIVLYEGYQ 289
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
25-199 |
3.92e-10 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 58.11 E-value: 3.92e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGldRP----TSGSLFFRDLDLTELEDREltkyrRDHVG--FVFQFYNL 98
Cdd:CHL00131 23 LKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG--HPaykiLEGDILFKGESILDLEPEE-----RAHLGifLAFQYPIE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLT-------AYENVAlvTEVAKSPMRP-------ADALALVGLEERMHH------FpaqlSGGEQQRVAIARAIAKR 158
Cdd:CHL00131 96 IPGVSnadflrlAYNSKR--KFQGLPELDPlefleiiNEKLKLVGMDPSFLSrnvnegF----SGGEKKRNEILQMALLD 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1869873813 159 PAVLLCDEPTGALDsktgirvIEAL----LGVNRQLGTTT--VIITH 199
Cdd:CHL00131 170 SELAILDETDSGLD-------IDALkiiaEGINKLMTSENsiILITH 209
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
36-203 |
4.86e-10 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 57.76 E-value: 4.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 36 EVVVLLGPSGSGKTTLLNIMGGLDRPTSGSL-----------FFRDldlTELEDReLTKYRRDHVGFVF--QFYNLVPSL 102
Cdd:cd03236 27 QVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppdwdeildEFRG---SELQNY-FTKLLEGDVKVIVkpQYVDLIPKA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYENVALVTEVAKSPMRP--ADALALVGLEERMhhfPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSK---TGI 177
Cdd:cd03236 103 VKGKVGELLKKKDERGKLDelVDQLELRHVLDRN---IDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKqrlNAA 179
|
170 180
....*....|....*....|....*.
gi 1869873813 178 RVIEALLgvnrQLGTTTVIITHNASI 203
Cdd:cd03236 180 RLIRELA----EDDNYVLVVEHDLAV 201
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
63-213 |
6.70e-10 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 58.89 E-value: 6.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 63 SGSLFFRDLDLTELEDRELtkyrRDHVGFVFQfYNLVPSLTAYENVALVTEVA-KSPMRPADALAlvGLEERMHHFPAQ- 140
Cdd:PTZ00265 1276 SGKILLDGVDICDYNLKDL----RNLFSIVSQ-EPMLFNMSIYENIKFGKEDAtREDVKRACKFA--AIDEFIESLPNKy 1348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 ----------LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGvADR 209
Cdd:PTZ00265 1349 dtnvgpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRiASIKR-SDK 1427
|
....
gi 1869873813 210 VLFF 213
Cdd:PTZ00265 1428 IVVF 1431
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
9-216 |
8.11e-10 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 56.96 E-value: 8.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRRDH 88
Cdd:cd03290 1 VQVTNGYFSWGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVpSLTAYENVALVTEVAKS---------PMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRP 159
Cdd:cd03290 81 VAYAAQKPWLL-NATVEENITFGSPFNKQrykavtdacSLQPDIDLLPFGDQTEIGERGINLSGGQRQRICVARALYQNT 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 160 AVLLCDEPTGALDSKTGIRVI-EALLGVNRQLGTTTVIITHNASIQGVADRVLFFADG 216
Cdd:cd03290 160 NIVFLDDPFSALDIHLSDHLMqEGILKFLQDDKRTLVLVTHKLQYLPHADWIIAMKDG 217
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
35-218 |
1.35e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 55.07 E-value: 1.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 35 KEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrrdhvgfvfqfynlvpsltayenvalvtev 114
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQ--------------------------------- 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 115 akspmrpadalalvGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIE----ALLGVNRQL 190
Cdd:smart00382 49 --------------LLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLleelRLLLLLKSE 114
|
170 180
....*....|....*....|....*...
gi 1869873813 191 GTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:smart00382 115 KNLTVILTTNDEKDLGPALLRRRFDRRI 142
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
22-215 |
2.10e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.35 E-value: 2.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDltELEDRELtKYRRDHVGFVFQ----FYN 97
Cdd:PTZ00265 398 VEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDSH--NLKDINL-KWWRSKIGVVSQdpllFSN 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 98 LVP-----SLTAYENVALVTEVAKSP-------------------------MRPADALALVGLEER-------------- 133
Cdd:PTZ00265 475 SIKnnikySLYSLKDLEALSNYYNEDgndsqenknkrnscrakcagdlndmSNTTDSNELIEMRKNyqtikdsevvdvsk 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 134 ---MHHF---------------PAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTV 195
Cdd:PTZ00265 555 kvlIHDFvsalpdkyetlvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITI 634
|
250 260
....*....|....*....|
gi 1869873813 196 IITHNASIQGVADRVLFFAD 215
Cdd:PTZ00265 635 IIAHRLSTIRYANTIFVLSN 654
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
25-227 |
2.94e-09 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 56.56 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGlDRPTSGS----LFFRdldlteledreltkyRR----------DHVG 90
Cdd:PRK10938 276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG-DHPQGYSndltLFGR---------------RRgsgetiwdikKHIG 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 FVFQFYNL---VPS------LTAY-ENVALVTEVAKSPMRPADA-LALVGLEERMHHFPAQ-LSGGEQQRVAIARAIAKR 158
Cdd:PRK10938 340 YVSSSLHLdyrVSTsvrnviLSGFfDSIGIYQAVSDRQQKLAQQwLDILGIDKRTADAPFHsLSWGQQRLALIVRALVKH 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 159 PAVLLCDEPTGALDsktgirvieallGVNRQL-----------GTTTVI-ITHNA--SIQGVADRVLFFADGRIARVRTN 224
Cdd:PRK10938 420 PTLLILDEPLQGLD------------PLNRQLvrrfvdvliseGETQLLfVSHHAedAPACITHRLEFVPDGDIYRYVQT 487
|
...
gi 1869873813 225 EVR 227
Cdd:PRK10938 488 KLN 490
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
26-166 |
3.35e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 54.88 E-value: 3.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 26 NEVDLEIT--EKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEdreltkyrRDHVGFVFQFYNLVPSLT 103
Cdd:PRK13541 15 NLFDLSITflPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIA--------KPYCTYIGHNLGLKLEMT 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 104 AYENVALVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:PRK13541 87 VFENLKFWSEIYNSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDE 149
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
10-213 |
3.89e-09 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 54.12 E-value: 3.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 10 ALTKTYVSGEVKVHALnevdlEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSlffrdldlTELeDRELTKYRRDHV 89
Cdd:cd03222 5 DCVKRYGVFFLLVELG-----VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDN--------DEW-DGITPVYKPQYI 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 90 gfvfqfynlvpsltayenvalvtevakspmrpadalalvgleermhhfpaQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:cd03222 71 --------------------------------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSA 100
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 170 ALDSKTGIRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFF 213
Cdd:cd03222 101 YLDIEQRLNAARAIRRLSEEGKKTALVVEHDlAVLDYLSDRIHVF 145
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
3-216 |
4.94e-09 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 56.27 E-value: 4.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 3 EAVFSAKALTKTY-VSGEVKVhALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGldRPTSG---------------SL 66
Cdd:TIGR00956 757 EDIFHWRNLTYEVkIKKEKRV-ILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAE--RVTTGvitggdrlvngrpldSS 833
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 67 FFR--------DLDLTELEDRELTKYRrdhvgfvfQFYNLVPSLTAYENVALVTEVAKSPMRPADALALVGLeermhhfP 138
Cdd:TIGR00956 834 FQRsigyvqqqDLHLPTSTVRESLRFS--------AYLRQPKSVSKSEKMEYVEEVIKLLEMESYADAVVGV-------P 898
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 139 AQ-LSGGEQQRVAIARAIAKRPAVLL-CDEPTGALDSKTGIRVIEALlgvnRQL---GTTTVIITHNASIQGVA--DRVL 211
Cdd:TIGR00956 899 GEgLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKLM----RKLadhGQAILCTIHQPSAILFEefDRLL 974
|
....*
gi 1869873813 212 FFADG 216
Cdd:TIGR00956 975 LLQKG 979
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
28-228 |
9.82e-09 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 54.80 E-value: 9.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 28 VDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfrdLDLTELEDRELTKYrRDHVGFVFQFYNLVPSLTAYEN 107
Cdd:COG4615 351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEIL---LDGQPVTADNREAY-RQLFSAVFSDFHLFDRLLGLDG 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 108 VALVTEVakspmrpADALALVGLEERMH----HF-PAQLSGGEQQRVAIARAIA-KRPaVLLCDEptGALDSKTGIRVI- 180
Cdd:COG4615 427 EADPARA-------RELLERLELDHKVSvedgRFsTTDLSQGQRKRLALLVALLeDRP-ILVFDE--WAADQDPEFRRVf 496
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1869873813 181 -EALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIARVRTNEVRR 228
Cdd:COG4615 497 yTELLPELKARGKTVIAISHDDRYFDLADRVLKMDYGKLVELTGPAALA 545
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
25-216 |
1.48e-08 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 53.71 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLL-NIMGGLDrPTSGSLffrdldlteledreltkYRRDHVGFVFQFYNLVPSlT 103
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLmLILGELE-PSEGKI-----------------KHSGRISFSSQFSWIMPG-T 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENValVTEVAKSPMRPADALALVGLEERMHHFPAQ-----------LSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:cd03291 114 IKENI--IFGVSYDEYRYKSVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYLD 191
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 173 SKTGIRVIEALLgVNRQLGTTTVIITHNASIQGVADRVLFFADG 216
Cdd:cd03291 192 VFTEKEIFESCV-CKLMANKTRILVTSKMEHLKKADKILILHEG 234
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
1-223 |
1.95e-08 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 53.97 E-value: 1.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 1 MSEAVFSAKALTKTYVSGEVK----VHALNEVDLEITEKEVVVLLGPSGSG--KTTLLNIMGGLD---RPTSGSLFF--- 68
Cdd:NF000106 1 MTRKTISNGARNAVEVRGLVKhfgeVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*GPDagrRPWRF*TWCanr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 69 RDLDLTELEDRELTKYRRDhvgfvfqfynlvpSLTAYENVALVTEVAKSPMRPADA-----LALVGLEERMHHFPAQLSG 143
Cdd:NF000106 81 RALRRTIG*HRPVR*GRRE-------------SFSGRENLYMIGR*LDLSRKDARAradelLERFSLTEAAGRAAAKYSG 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 144 GEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHN-------ASIQGVADRVLFFADG 216
Cdd:NF000106 148 GMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYmeeaeqlAHELTVIDRGRVIADG 226
|
....*..
gi 1869873813 217 RIARVRT 223
Cdd:NF000106 227 KVDELKT 233
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
40-199 |
2.15e-08 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 53.74 E-value: 2.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 40 LLGPSGSGKTTLLNIMGGLDRPTSGSLF-------------------FRDLDLTELEDREL--TKYRRDHVgfvfqfYNL 98
Cdd:PRK15064 32 LIGANGCGKSTFMKILGGDLEPSAGNVSldpnerlgklrqdqfafeeFTVLDTVIMGHTELweVKQERDRI------YAL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 vPSLTA--YENVA-LVTEVAK-----SPMRPADALALVGLEERMHHFP-AQLSGGEQQRVAIARAIAKRPAVLLCDEPTG 169
Cdd:PRK15064 106 -PEMSEedGMKVAdLEVKFAEmdgytAEARAGELLLGVGIPEEQHYGLmSEVAPGWKLRVLLAQALFSNPDILLLDEPTN 184
|
170 180 190
....*....|....*....|....*....|
gi 1869873813 170 ALDSKTgIRVIEALLgvnRQLGTTTVIITH 199
Cdd:PRK15064 185 NLDINT-IRWLEDVL---NERNSTMIIISH 210
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
34-199 |
6.08e-08 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 52.48 E-value: 6.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 34 EKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSL-----------FFRDldlTELEDReLTKYRRDHVGFVF--QFYNLVP 100
Cdd:COG1245 98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYdeepswdevlkRFRG---TELQDY-FKKLANGEIKVAHkpQYVDLIP 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 101 S---------LTAYENVALVTEVAKspmrpadalaLVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:COG1245 174 KvfkgtvrelLEKVDERGKLDELAE----------KLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYL 243
|
170 180 190
....*....|....*....|....*....|.
gi 1869873813 172 DSKTGIRVIEALlgvnRQL---GTTTVIITH 199
Cdd:COG1245 244 DIYQRLNVARLI----RELaeeGKYVLVVEH 270
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
141-218 |
6.75e-08 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 52.31 E-value: 6.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALD--SKtgiRVIEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADGR 217
Cdd:PRK10762 396 LSGGNQQKVAIARGLMTRPKVLILDEPTRGVDvgAK---KEIYQLINQFKAEGLSIILVSSEmPEVLGMSDRILVMHEGR 472
|
.
gi 1869873813 218 I 218
Cdd:PRK10762 473 I 473
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
24-223 |
1.01e-07 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 50.87 E-value: 1.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 24 ALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELtkyrRDHVGFVFQFYNLVpSLT 103
Cdd:cd03369 23 VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDL----RSSLTIIPQDPTLF-SGT 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENVALVTEVAKSPMRPADALALVGLeermhhfpaQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTgirviEAL 183
Cdd:cd03369 98 IRSNLDPFDEYSDEEIYGALRVSEGGL---------NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYAT-----DAL 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1869873813 184 L-GVNRQL--GTTTVIITHNasIQGVA--DRVLFFADGRIARVRT 223
Cdd:cd03369 164 IqKTIREEftNSTILTIAHR--LRTIIdyDKILVMDAGEVKEYDH 206
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
124-211 |
1.80e-07 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 51.37 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 124 ALALVGLEermhHFP-----AQLSGGEQQRVAIAR---AIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQlGTTTV 195
Cdd:PRK00635 792 ALCSLGLD----YLPlgrplSSLSGGEIQRLKLAYellAPSKKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQ-GHTVV 866
|
90
....*....|....*.
gi 1869873813 196 IITHNASIQGVADRVL 211
Cdd:PRK00635 867 IIEHNMHVVKVADYVL 882
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
139-218 |
2.01e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 51.08 E-value: 2.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 139 AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD--SKTGI-RVIEALLgvnrQLGTTTVIITHN-ASIQGVADRVLFFA 214
Cdd:PRK13549 404 ARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDvgAKYEIyKLINQLV----QQGVAIIVISSElPEVLGLSDRVLVMH 479
|
....
gi 1869873813 215 DGRI 218
Cdd:PRK13549 480 EGKL 483
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
25-203 |
2.05e-07 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 50.17 E-value: 2.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLD--RPTSGSLFFRDLDLTELEDRELTKyrrDHVGFVFQFYNLVPSL 102
Cdd:PRK09580 17 LRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRAG---EGIFMAFQYPVEIPGV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TA--YENVALVTEVAKSPMRPADALALVGL-EERMH--HFPAQL---------SGGEQQRVAIARAIAKRPAVLLCDEPT 168
Cdd:PRK09580 94 SNqfFLQTALNAVRSYRGQEPLDRFDFQDLmEEKIAllKMPEDLltrsvnvgfSGGEKKRNDILQMAVLEPELCILDESD 173
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1869873813 169 GALDsktgirvIEALL----GVN--RQLGTTTVIITHNASI 203
Cdd:PRK09580 174 SGLD-------IDALKivadGVNslRDGKRSFIIVTHYQRI 207
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
11-200 |
2.35e-07 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 51.17 E-value: 2.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 11 LTKTYvSGeVKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGslffrdlDLTELEDRELTKYRRDH-- 88
Cdd:TIGR01257 1943 LTKVY-SG-TSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSG-------DATVAGKSILTNISDVHqn 2013
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 VGFVFQFYNLVPSLTAYENVALVTEVAKSPMRPADALA-----LVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLL 163
Cdd:TIGR01257 2014 MGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVAnwsiqSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVL 2093
|
170 180 190
....*....|....*....|....*....|....*..
gi 1869873813 164 CDEPTGALDSKTGIRVIEALLGVNRQlGTTTVIITHN 200
Cdd:TIGR01257 2094 LDEPTTGMDPQARRMLWNTIVSIIRE-GRAVVLTSHS 2129
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
23-218 |
2.55e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 50.89 E-value: 2.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRdldlteledreltkyrRDHVGFVFQFyNLVPSL 102
Cdd:PLN03130 631 PTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELPPRSDASVVI----------------RGTVAYVPQV-SWIFNA 693
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 TAYENVALVTEVakSPMRPADALALVGLEERMHHFPA-----------QLSGGEQQRVAIARAIAKRPAVLLCDEPTGAL 171
Cdd:PLN03130 694 TVRDNILFGSPF--DPERYERAIDVTALQHDLDLLPGgdlteigergvNISGGQKQRVSMARAVYSNSDVYIFDDPLSAL 771
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 172 DSKTGIRVIEALLgvNRQL-GTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PLN03130 772 DAHVGRQVFDKCI--KDELrGKTRVLVTNQLHFLSQVDRIILVHEGMI 817
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
37-199 |
2.69e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 50.58 E-value: 2.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 37 VVVLLGPSGSGKTTLLNIMGGLDRPTSGSL-----------FFRDldlTELEDReLTKYRRDHVGFVF--QFYNLVPSL- 102
Cdd:PRK13409 101 VTGILGPNGIGKTTAVKILSGELIPNLGDYeeepswdevlkRFRG---TELQNY-FKKLYNGEIKVVHkpQYVDLIPKVf 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 103 --TAYENVALVTEVAKspmrpADALA-LVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRV 179
Cdd:PRK13409 177 kgKVRELLKKVDERGK-----LDEVVeRLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNV 251
|
170 180
....*....|....*....|..
gi 1869873813 180 IEALlgvnRQL--GTTTVIITH 199
Cdd:PRK13409 252 ARLI----RELaeGKYVLVVEH 269
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
139-218 |
2.71e-07 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 50.59 E-value: 2.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 139 AQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDskTGIRV-IEALLGVNRQLGTTTVIITHN-ASIQGVADRVLFFADG 216
Cdd:TIGR02633 402 GRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVD--VGAKYeIYKLINQLAQEGVAIIVVSSElAEVLGLSDRVLVIGEG 479
|
..
gi 1869873813 217 RI 218
Cdd:TIGR02633 480 KL 481
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
42-219 |
3.16e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 50.50 E-value: 3.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 42 GPSGSGKTTLLNIMGGLDRPTSGslffrdldltELEDRELTKyrrdhVGFVFQFY-NLVPSLTAYENV---ALVTEVAKS 117
Cdd:PRK11819 357 GPNGAGKSTLFKMITGQEQPDSG----------TIKIGETVK-----LAYVDQSRdALDPNKTVWEEIsggLDIIKVGNR 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 118 PM-----------RPADALALVGleermhhfpaQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTgIRVIE-ALLg 185
Cdd:PRK11819 422 EIpsrayvgrfnfKGGDQQKKVG----------VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVET-LRALEeALL- 489
|
170 180 190
....*....|....*....|....*....|....
gi 1869873813 186 vnrQLGTTTVIITHnasiqgvaDRvlFFADgRIA 219
Cdd:PRK11819 490 ---EFPGCAVVISH--------DR--WFLD-RIA 509
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
40-184 |
3.77e-07 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 50.33 E-value: 3.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 40 LLGPSGSGKTTLLNIMGGLDRPTSGSLFFRdldlTELEDRELTKYRRDhvgfvfqfynLVPSLTAYENVA------LVTE 113
Cdd:PRK11147 350 LIGPNGCGKTTLLKLMLGQLQADSGRIHCG----TKLEVAYFDQHRAE----------LDPEKTVMDNLAegkqevMVNG 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 114 VAK-----------SPMR---PADAlalvgleermhhfpaqLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTgIRV 179
Cdd:PRK11147 416 RPRhvlgylqdflfHPKRamtPVKA----------------LSGGERNRLLLARLFLKPSNLLILDEPTNDLDVET-LEL 478
|
....*
gi 1869873813 180 IEALL 184
Cdd:PRK11147 479 LEELL 483
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
141-211 |
1.10e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 48.86 E-value: 1.10e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 141 LSGGEQQRVAIARAIAKR---PAVLLCDEPTGAL---DSKTGIRVIEALLGvnrqLGTTTVIITHNASIQGVADRVL 211
Cdd:TIGR00630 830 LSGGEAQRIKLAKELSKRstgRTLYILDEPTTGLhfdDIKKLLEVLQRLVD----KGNTVVVIEHNLDVIKTADYII 902
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
141-231 |
1.14e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 48.75 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALD--SKTGI-RVIEALlgvnRQLGTTTVIITHN-ASIQGVADRVLFFADG 216
Cdd:PRK11288 397 LSGGNQQKAILGRWLSEDMKVILLDEPTRGIDvgAKHEIyNVIYEL----AAQGVAVLFVSSDlPEVLGVADRIVVMREG 472
|
90
....*....|....*
gi 1869873813 217 RIArvrtNEVRREAA 231
Cdd:PRK11288 473 RIA----GELAREQA 483
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
141-229 |
1.22e-06 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 48.57 E-value: 1.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFADGRIAR 220
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAG 471
|
90
....*....|
gi 1869873813 221 -VRTNEVRRE 229
Cdd:PRK10982 472 iVDTKTTTQN 481
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
29-211 |
1.25e-06 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 47.60 E-value: 1.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 29 DLEIT-EKEVVVLLGPSGSGKTTLLN-----IMGGLDRPTSGSLFFRD------------LDLTELEDRELTKYRrdhvg 90
Cdd:cd03240 15 RSEIEfFSPLTLIVGQNGAGKTTIIEalkyaLTGELPPNSKGGAHDPKliregevraqvkLAFENANGKKYTITR----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 91 fvfqfynlvpSLTAYENVALVtevakspmRPADALALVgleERMhhfPAQLSGGEQQ------RVAIARAIAKRPAVLLC 164
Cdd:cd03240 90 ----------SLAILENVIFC--------HQGESNWPL---LDM---RGRCSGGEKVlasliiRLALAETFGSNCGILAL 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 165 DEPTGALDS----KTGIRVIEALLG-VNRQLgtttVIITHNASIQGVADRVL 211
Cdd:cd03240 146 DEPTTNLDEenieESLAEIIEERKSqKNFQL----IVITHDEELVDAADHIY 193
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
25-216 |
1.30e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 48.75 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLN-IMGgldrptsgslffrdldltELEDRELTKYRRDHVGFVFQFYNLVPSlT 103
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMmIMG------------------ELEPSEGKIKHSGRISFSPQTSWIMPG-T 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 104 AYENValVTEVAKSPMRPADALALVGLEERMHHFPAQ-----------LSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:TIGR01271 503 IKDNI--IFGLSYDEYRYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1869873813 173 SKTGIRVIEALLgVNRQLGTTTVIITHNASIQGVADRVLFFADG 216
Cdd:TIGR01271 581 VVTEKEIFESCL-CKLMSNKTRILVTSKLEHLKKADKILLLHEG 623
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
141-211 |
1.91e-06 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 47.61 E-value: 1.91e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1869873813 141 LSGGEQQRVAIARAIAKR---PAVLLCDEPTgaldskTGIRV--IEALLGVNRQL---GTTTVIITHNASIQGVADRVL 211
Cdd:cd03271 170 LSGGEAQRIKLAKELSKRstgKTLYILDEPT------TGLHFhdVKKLLEVLQRLvdkGNTVVVIEHNLDVIKCADWII 242
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
17-217 |
4.75e-06 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 47.05 E-value: 4.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 17 SGEVKVHALNevdLEITEKEVVVLLGPSGSGKTTLLNIMGGLdRPTSGSLffrdldlteledreLTKYRRDHVGFVFQfy 96
Cdd:TIGR00954 463 NGDVLIESLS---FEVPSGNNLLICGPNGCGKSSLFRILGEL-WPVYGGR--------------LTKPAKGKLFYVPQ-- 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 97 nlvpslTAYENVALVTEVAKSPMRPAD-------------ALALVGLE---ERMHHFPA------QLSGGEQQRVAIARA 154
Cdd:TIGR00954 523 ------RPYMTLGTLRDQIIYPDSSEDmkrrglsdkdleqILDNVQLThilEREGGWSAvqdwmdVLSGGEKQRIAMARL 596
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 155 IAKRPAVLLCDEPTGALdsktGIRVIEALLGVNRQLGTTTVIITHNASIQGVADRVLFFaDGR 217
Cdd:TIGR00954 597 FYHKPQFAILDECTSAV----SVDVEGYMYRLCREFGITLFSVSHRKSLWKYHEYLLYM-DGR 654
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
38-219 |
6.12e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 46.78 E-value: 6.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 38 VVLLGPSGSGKTTLLNIMGGLDRPTSGSLFfRDLDLteledrELTKYRRDHV-GFVFQFYNLVPSLTAYENValvtevak 116
Cdd:PLN03073 538 IAMVGPNGIGKSTILKLISGELQPSSGTVF-RSAKV------RMAVFSQHHVdGLDLSSNPLLYMMRCFPGV-------- 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 117 sPMRPADA-LALVGLEERMHHFPA-QLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDsktgIRVIEALLGVNRQLGTTT 194
Cdd:PLN03073 603 -PEQKLRAhLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD----LDAVEALIQGLVLFQGGV 677
|
170 180
....*....|....*....|....*.
gi 1869873813 195 VIITHNAS-IQGVADRVLFFADGRIA 219
Cdd:PLN03073 678 LMVSHDEHlISGSVDELWVVSEGKVT 703
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
25-218 |
7.19e-06 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 46.32 E-value: 7.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 25 LNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSL-----------------FFRDLD-----LTELEDRELT 82
Cdd:PRK10636 328 LDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIglakgiklgyfaqhqleFLRADEsplqhLARLAPQELE 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 83 KYRRDHVG-FVFQFYNlvpsltayenvalVTEVAkspmrpadalalvgleermhhfpAQLSGGEQQRVAIARAIAKRPAV 161
Cdd:PRK10636 408 QKLRDYLGgFGFQGDK-------------VTEET-----------------------RRFSGGEKARLVLALIVWQRPNL 451
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 162 LLCDEPTGALDSKTGIRVIEALLGVNRQLgtttVIITHNAS-IQGVADRVLFFADGRI 218
Cdd:PRK10636 452 LLLDEPTNHLDLDMRQALTEALIDFEGAL----VVVSHDRHlLRSTTDDLYLVHDGKV 505
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
23-66 |
9.64e-06 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 45.58 E-value: 9.64e-06
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSL 66
Cdd:PRK13546 38 FALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV 81
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
141-200 |
1.13e-05 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 45.79 E-value: 1.13e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1869873813 141 LSGGEQQRVAIARAIAKR---PAVLLCDEPTgaldskTG-----IRVieaLLGVNRQL---GTTTVIITHN 200
Cdd:COG0178 827 LSGGEAQRVKLASELSKRstgKTLYILDEPT------TGlhfhdIRK---LLEVLHRLvdkGNTVVVIEHN 888
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
140-200 |
1.23e-05 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 44.27 E-value: 1.23e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1869873813 140 QLSGGEQQRVAIA-----RAIAKRPAVLLcDEPTGALDSKTGIRVIEALLGvNRQLGTTTVIITHN 200
Cdd:cd03227 77 QLSGGEKELSALAlilalASLKPRPLYIL-DEIDRGLDPRDGQALAEAILE-HLVKGAQVIVITHL 140
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
23-66 |
1.97e-05 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 44.88 E-value: 1.97e-05
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSL 66
Cdd:PRK13545 38 YALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV 81
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
22-217 |
2.07e-05 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 44.72 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 22 VHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKyrrDHVGFVFQFYNLVPS 101
Cdd:PRK10982 11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALE---NGISMVHQELNLVLQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 102 LTAYENVALvtevAKSPMRpadalALVGLEERMHH-----FP------------AQLSGGEQQRVAIARAIAKRPAVLLC 164
Cdd:PRK10982 88 RSVMDNMWL----GRYPTK-----GMFVDQDKMYRdtkaiFDeldididprakvATLSVSQMQMIEIAKAFSYNAKIVIM 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1869873813 165 DEPTGALDSKTgirvIEALLGVNRQL---GTTTVIITHNA-SIQGVADRVLFFADGR 217
Cdd:PRK10982 159 DEPTSSLTEKE----VNHLFTIIRKLkerGCGIVYISHKMeEIFQLCDEITILRDGQ 211
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
32-218 |
3.52e-05 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 44.58 E-value: 3.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 32 ITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTE--LED--RELTKYRRDHVGFVFQF-YNLVPsLTAYE 106
Cdd:PLN03232 1259 VSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgLTDlrRVLSIIPQSPVLFSGTVrFNIDP-FSEHN 1337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 107 NVALVTEVAKSPMRPADALALVGLEERMHHFPAQLSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGIRVIEALLGV 186
Cdd:PLN03232 1338 DADLWEALERAHIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRTDSLIQRTIREE 1417
|
170 180 190
....*....|....*....|....*....|..
gi 1869873813 187 NRQlgTTTVIITHNASIQGVADRVLFFADGRI 218
Cdd:PLN03232 1418 FKS--CTMLVIAHRLNTIIDCDKILVLSSGQV 1447
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
21-168 |
6.81e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 43.57 E-value: 6.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRDLDLTELEDRELTKYRrdhVGFVFQFY--NL 98
Cdd:NF033858 13 KTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAVCPR---IAYMPQGLgkNL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 99 VPSLTAYENVAL--------VTEVAKspmRPADALALVGLE---ERmhhfPA-QLSGGEQQRVAIARAIAKRPAVLLCDE 166
Cdd:NF033858 90 YPTLSVFENLDFfgrlfgqdAAERRR---RIDELLRATGLApfaDR----PAgKLSGGMKQKLGLCCALIHDPDLLILDE 162
|
..
gi 1869873813 167 PT 168
Cdd:NF033858 163 PT 164
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
138-200 |
9.07e-05 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 43.14 E-value: 9.07e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 138 PA-QLSGGEQQRVAIARAIAKRPA-----VLlcDEPTgaldskTGIRV--IEALLGV-NR--QLGTTTVIITHN 200
Cdd:PRK00349 827 PAtTLSGGEAQRVKLAKELSKRSTgktlyIL--DEPT------TGLHFedIRKLLEVlHRlvDKGNTVVVIEHN 892
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
9-198 |
1.09e-04 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 42.15 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLdRPTSGSLffrDLDLTELEDRELTKYRRdh 88
Cdd:cd03289 6 KDLTAKYTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-LNTEGDI---QIDGVSWNSVPLQKWRK-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 vGF------VFQF-----YNLVP-SLTAYENVALVTEVakspmrpadalalVGLEERMHHFPAQL-----------SGGE 145
Cdd:cd03289 78 -AFgvipqkVFIFsgtfrKNLDPyGKWSDEEIWKVAEE-------------VGLKSVIEQFPGQLdfvlvdggcvlSHGH 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1869873813 146 QQRVAIARAIAKRPAVLLCDEPTGALDSKTgIRVIEALLgvNRQLGTTTVIIT 198
Cdd:cd03289 144 KQLMCLARSVLSKAKILLLDEPSAHLDPIT-YQVIRKTL--KQAFADCTVILS 193
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
26-201 |
1.41e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 41.53 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 26 NEVDLEiteKEVVVLLGPSGSGKTTLLN-IMGGL-DRPTSGSLFFRDL----------DLT-ELEDRELTKYRRDhvGFV 92
Cdd:COG0419 17 ETIDFD---DGLNLIVGPNGAGKSTILEaIRYALyGKARSRSKLRSDLinvgseeasvELEfEHGGKRYRIERRQ--GEF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 93 FQFYNLVPS-----------LTAYENVALVTEVAKSPMRP--ADALALVGLEE----RMHHF--PAQLSGGEQQRVAIAR 153
Cdd:COG0419 92 AEFLEAKPSerkealkrllgLEIYEELKERLKELEEALESalEELAELQKLKQeilaQLSGLdpIETLSGGERLRLALAD 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1869873813 154 AIAkrpavLLCDepTGALDSKTGIRVIEALlgvnRQLGtttvIITHNA 201
Cdd:COG0419 172 LLS-----LILD--FGSLDEERLERLLDAL----EELA----IITHVI 204
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
9-175 |
1.42e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 42.59 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 9 KALTKTYVSGEVKVhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLdRPTSGSLffrDLDLTELEDRELTKYRRDh 88
Cdd:TIGR01271 1221 QGLTAKYTEAGRAV--LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEI---QIDGVSWNSVTLQTWRKA- 1293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 89 vgfvfqfYNLVPsltayENVALVTEVAKSPMRPADALA---------LVGLEERMHHFPAQL-----------SGGEQQR 148
Cdd:TIGR01271 1294 -------FGVIP-----QKVFIFSGTFRKNLDPYEQWSdeeiwkvaeEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQL 1361
|
170 180
....*....|....*....|....*..
gi 1869873813 149 VAIARAIAKRPAVLLCDEPTGALDSKT 175
Cdd:TIGR01271 1362 MCLARSILSKAKILLLDEPSAHLDPVT 1388
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
8-183 |
2.35e-04 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 41.80 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVSGEVkvhaLNEVDLEITEKEVVVLLGPSGSGKTTLLNIMGGLDRPTSGSLFFRdldltelEDRELTKYRRD 87
Cdd:PRK15064 322 VENLTKGFDNGPL----FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWS-------ENANIGYYAQD 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 88 HVgfvFQFYNlvpSLTAYENVALVTEVAKspmrpaDALALVGLEERMHhFPAQ--------LSGGEQQRVAIARAIAKRP 159
Cdd:PRK15064 391 HA---YDFEN---DLTLFDWMSQWRQEGD------DEQAVRGTLGRLL-FSQDdikksvkvLSGGEKGRMLFGKLMMQKP 457
|
170 180
....*....|....*....|....
gi 1869873813 160 AVLLCDEPTGALDsktgIRVIEAL 183
Cdd:PRK15064 458 NVLVMDEPTNHMD----MESIESL 477
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
141-210 |
2.45e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 41.92 E-value: 2.45e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1869873813 141 LSGGEQQRVAIARAI-AKRPAVL-LCDEPTGALDSKTGIRVIEALLGVnRQLGTTTVIITHNASIQGVADRV 210
Cdd:TIGR00630 489 LSGGEAQRIRLATQIgSGLTGVLyVLDEPSIGLHQRDNRRLINTLKRL-RDLGNTLIVVEHDEDTIRAADYV 559
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
139-211 |
4.93e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 40.97 E-value: 4.93e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1869873813 139 AQLSGGEQQRVAIARAI-AKRPAVL-LCDEPTGAL---DSKTGIRVIEALlgvnRQLGTTTVIITHNASIQGVADRVL 211
Cdd:PRK00635 475 ATLSGGEQERTALAKHLgAELIGITyILDEPSIGLhpqDTHKLINVIKKL----RDQGNTVLLVEHDEQMISLADRII 548
|
|
| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
8-84 |
7.29e-04 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 39.30 E-value: 7.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 8 AKALTKTYVSGEVKVHALNEVD-------LEITEKEVVVLLGPSGSGKTTLLN-IMGGLDRPTSG--------------- 64
Cdd:cd01854 51 LEELLEIYEKLGYPVLAVSAKTgegldelRELLKGKTSVLVGQSGVGKSTLLNaLLPELVLATGEiseklgrgrhttthr 130
|
90 100 110
....*....|....*....|....*....|...
gi 1869873813 65 SLF-------------FRDLDLTELEDRELTKY 84
Cdd:cd01854 131 ELFplpgggliidtpgFRELGLLHIDPEELAEY 163
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
120-172 |
8.04e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 40.23 E-value: 8.04e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1869873813 120 RPADALALVGLEERMHHFPA-QLSGGEQQRVAIARAIAKRPAVLLCDEPTGALD 172
Cdd:PLN03073 323 RAASILAGLSFTPEMQVKATkTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
21-51 |
2.68e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 38.46 E-value: 2.68e-03
10 20 30
....*....|....*....|....*....|.
gi 1869873813 21 KVHALNEVDLEITEKEVVVLLGPSGSGKTTL 51
Cdd:TIGR00630 8 REHNLKNIDVEIPRDKLVVITGLSGSGKSSL 38
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
20-53 |
4.01e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 38.07 E-value: 4.01e-03
10 20 30
....*....|....*....|....*....|....
gi 1869873813 20 VKVHALNEVDLEITEKEVVVLLGPSGSGKTTLLN 53
Cdd:TIGR00630 619 ARENNLKNITVSIPLGLFTCITGVSGSGKSTLIN 652
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
141-219 |
5.36e-03 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 37.62 E-value: 5.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALDSKTGiRVIEALlgVNRQLGTTTVI-ITHNASIQGVADRVLFFADGRIA 219
Cdd:TIGR00957 1422 LSVGQRQLVCLARALLRKTKILVLDEATAAVDLETD-NLIQST--IRTQFEDCTVLtIAHRLNTIMDYTRVIVLDKGEVA 1498
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
141-231 |
5.57e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 37.46 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1869873813 141 LSGGEQQRVAIARAIAKRPAVLLCDEPTGALD--SKTGIRVIeallgVNrQL---GTTTVIIThnaS----IQGVADRVL 211
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDvgAKYEIYTI-----IN-ELaaeGKGVIVIS---SelpeLLGMCDRIY 475
|
90 100
....*....|....*....|
gi 1869873813 212 FFADGRIarvrTNEVRREAA 231
Cdd:NF040905 476 VMNEGRI----TGELPREEA 491
|
|
| FlhF |
TIGR03499 |
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility] |
7-50 |
5.64e-03 |
|
flagellar biosynthetic protein FlhF; [Cellular processes, Chemotaxis and motility]
Pssm-ID: 274609 [Multi-domain] Cd Length: 282 Bit Score: 37.31 E-value: 5.64e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1869873813 7 SAKALTKTYVSGEVKVHALNEVDLEitEKEVVVLLGPSGSGKTT 50
Cdd:TIGR03499 168 DAWRWLREALEGMLPVKPEEDPILE--QGGVIALVGPTGVGKTT 209
|
|
| AAA_29 |
pfam13555 |
P-loop containing region of AAA domain; |
23-52 |
7.11e-03 |
|
P-loop containing region of AAA domain;
Pssm-ID: 433304 [Multi-domain] Cd Length: 61 Bit Score: 34.11 E-value: 7.11e-03
10 20 30
....*....|....*....|....*....|
gi 1869873813 23 HALNEVDLEITEKEVVVLLGPSGSGKTTLL 52
Cdd:pfam13555 10 GTFDGHTIPIDPRGNTLLTGPSGSGKSTLL 39
|
|
| |
