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Conserved domains on  [gi|1876456502|ref|WP_180344223|]
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tetratricopeptide repeat protein [Aeromonas allosaccharophila]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 708416)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 141-355 1.99e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.64  E-value: 1.99e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 141 LQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLA 220
Cdd:COG3914     6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 221 GLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLS---GYQPDLAsnmDYYATWAGLTQELGQN 297
Cdd:COG3914    86 LLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRralALNPDFA---EAYLNLGEALRRLGRL 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1876456502 298 ADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL-LHGNLGEASTNWL 355
Cdd:COG3914   163 EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALeLDPDNADAHSNLL 221
PRK07003 super family cl35530
DNA polymerase III subunit gamma/tau;
62-196 4.08e-04

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07003:

Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.53  E-value: 4.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  62 PVVAASEVVAPDAVTPDVVTRAAAPVSQSEPVEVA----------AALPLPSQDEVNDEAGEGDSGDTADGAPFDASSDV 131
Cdd:PRK07003  402 VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAdrgddaadgdAPVPAKANARASADSRCDERDAQPPADSGSASAPA 481

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1876456502 132 DESEPtDEELQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLR 196
Cdd:PRK07003  482 SDAPP-DAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAAR 545
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 141-355 1.99e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.64  E-value: 1.99e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 141 LQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLA 220
Cdd:COG3914     6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 221 GLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLS---GYQPDLAsnmDYYATWAGLTQELGQN 297
Cdd:COG3914    86 LLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRralALNPDFA---EAYLNLGEALRRLGRL 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1876456502 298 ADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL-LHGNLGEASTNWL 355
Cdd:COG3914   163 EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALeLDPDNADAHSNLL 221
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 186-350 1.31e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.96  E-value: 1.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 186 ATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQ 265
Cdd:TIGR02917 506 ARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKK 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 266 ALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL-LH 344
Cdd:TIGR02917 586 ALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALeLK 665


                  ....*.
gi 1876456502 345 GNLGEA 350
Cdd:TIGR02917 666 PDNTEA 671
TPR_19 pfam14559
Tetratricopeptide repeat;
193-256 6.84e-06

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 43.34  E-value: 6.84e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1876456502 193 GSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARL 256
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
62-196 4.08e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.53  E-value: 4.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  62 PVVAASEVVAPDAVTPDVVTRAAAPVSQSEPVEVA----------AALPLPSQDEVNDEAGEGDSGDTADGAPFDASSDV 131
Cdd:PRK07003  402 VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAdrgddaadgdAPVPAKANARASADSRCDERDAQPPADSGSASAPA 481

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1876456502 132 DESEPtDEELQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLR 196
Cdd:PRK07003  482 SDAPP-DAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAAR 545
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 176-342 8.04e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 38.14  E-value: 8.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  176 KELAALAERKATTAMAKGsLRDAQDN--YYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLL 253
Cdd:PRK11447   565 QELAQRLQSDQVLETANR-LRDSGKEaeAEALLRQQPPSTRIDLTLADWAQQRGDYAAARAAYQRVLTREPGNADARLGL 643

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  254 ARLAISEGQQQQALGWLSgyQPDLASNMDYYA------TWAGLtqelGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDG 327
Cdd:PRK11447   644 IEVDIAQGDLAAARAQLA--KLPATANDSLNTqrrvalAWAAL----GDTAAAQRTFNRLIPQAKSQPPSMESALVLRDA 717

                          170       180
                   ....*....|....*....|.
gi 1876456502  328 ------QGHSQRALDAYRNAL 342
Cdd:PRK11447   718 arfeaqTGQPQQALETYKDAM 738
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 141-355 1.99e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.64  E-value: 1.99e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 141 LQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLA 220
Cdd:COG3914     6 LLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 221 GLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLS---GYQPDLAsnmDYYATWAGLTQELGQN 297
Cdd:COG3914    86 LLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRralALNPDFA---EAYLNLGEALRRLGRL 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1876456502 298 ADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL-LHGNLGEASTNWL 355
Cdd:COG3914   163 EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALeLDPDNADAHSNLL 221
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 139-321 7.81e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 72.72  E-value: 7.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 139 EELQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQ 218
Cdd:COG3914    38 AAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFN 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 219 LAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQA---LGWLSGYQPDLAsnmDYYATWAGLTQELG 295
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAiaaLRRALELDPDNA---EALNNLGNALQDLG 194

                         170       180
                  ....*....|....*....|....*.
gi 1876456502 296 QNADAAALYVKLLRQQPDQGRWWLGL 321
Cdd:COG3914   195 RLEEAIAAYRRALELDPDNADAHSNL 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 186-350 1.31e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.96  E-value: 1.31e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 186 ATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQ 265
Cdd:TIGR02917 506 ARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKK 585

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 266 ALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL-LH 344
Cdd:TIGR02917 586 ALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALeLK 665


                  ....*.
gi 1876456502 345 GNLGEA 350
Cdd:TIGR02917 666 PDNTEA 671
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 171-342 1.61e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.06  E-value: 1.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 171 VELSAKELAALAERkATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFR 250
Cdd:COG2956    69 LERDPDRAEALLEL-AQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAY 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 251 LLLARLAISEGQQQQALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGH 330
Cdd:COG2956   148 CELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGD 227

                         170
                  ....*....|..
gi 1876456502 331 SQRALDAYRNAL 342
Cdd:COG2956   228 PEEALELLRKAL 239
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 190-342 4.48e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.52  E-value: 4.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 190 MAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGW 269
Cdd:COG2956    53 RRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEV 132

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1876456502 270 LSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL 342
Cdd:COG2956   133 LERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL 205
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 177-314 9.06e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.13  E-value: 9.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 177 ELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARL 256
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1876456502 257 AISEGQQQQALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQ 314
Cdd:COG4783    82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 185-342 1.50e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 1.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 185 KATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQ 264
Cdd:COG2956    14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1876456502 265 QALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL 342
Cdd:COG2956    94 RAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 144-311 4.46e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 59.74  E-value: 4.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 144 ELYAELAAEQQAVASAprkpgvlkiETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLL 223
Cdd:COG2956   118 EIYEQEGDWEKAIEVL---------ERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 224 YGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLSGYQpDLASNMDYYATWAGLTQELGQNADAAAL 303
Cdd:COG2956   189 LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL-ELDPSDDLLLALADLLERKEGLEAALAL 267


                  ....*...
gi 1876456502 304 YVKLLRQQ 311
Cdd:COG2956   268 LERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 215-342 6.85e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 6.85e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 215 AREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLSGYQPDLASNMDYYATWAGLTQEL 294
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1876456502 295 GQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL 342
Cdd:COG4783    86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 171-342 9.18e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 9.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 171 VELSAKELAALaERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFR 250
Cdd:COG2956   103 LELDPDDAEAL-RLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARAL 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 251 LLLARLAISEGQQQQALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQgRWWLGLGVAEDGQGH 330
Cdd:COG2956   182 LLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEG 260

                         170
                  ....*....|..
gi 1876456502 331 SQRALDAYRNAL 342
Cdd:COG2956   261 LEAALALLERQL 272
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 136-268 9.53e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.10  E-value: 9.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 136 PTDEELQPEL---YAELAAEQQAVASAPRKPGvlkietveLSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYN 212
Cdd:TIGR02917  87 YPKNQVLPLLaraYLLQGKFQQVLDELPGKTL--------LDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRS 158

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1876456502 213 QGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALG 268
Cdd:TIGR02917 159 LYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALA 214
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
171-358 4.75e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.17  E-value: 4.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 171 VELSAKELAALAERkATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFR 250
Cdd:COG0457     1 LELDPDDAEAYNNL-GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEAL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 251 LLLARLAISEGQQQQALGWlsgYQPDLASNMDYYATWAGLT---QELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDG 327
Cdd:COG0457    80 NNLGLALQALGRYEEALED---YDKALELDPDDAEALYNLGlalLELGRYDEAIEAYERALELDPDDADALYNLGIALEK 156

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1876456502 328 QGHSQRALDAYRNALLHGNLGEASTNWLEQR 358
Cdd:COG0457   157 LGRYEEALELLEKLEAAALAALLAAALGEAA 187
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
189-270 5.61e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.09  E-value: 5.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 189 AMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQlLEEGIRLDPQQADFRLLLARLAISEGQQQQALG 268
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                  ..
gi 1876456502 269 WL 270
Cdd:COG3063    81 YL 82
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 231-342 7.27e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.69  E-value: 7.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 231 EARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQ 310
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1876456502 311 QPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL 342
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 206-319 1.09e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 1.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 206 LAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLS---GYQPDlasNMD 282
Cdd:COG4235    10 LAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLEralALDPD---NPE 86

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1876456502 283 YYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWL 319
Cdd:COG4235    87 ALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 186-292 1.37e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 186 ATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQ 265
Cdd:COG4235    24 GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAE 103

                          90       100
                  ....*....|....*....|....*..
gi 1876456502 266 ALGWLSGYQPDLASNMDYYATWAGLTQ 292
Cdd:COG4235   104 AIAAWQKLLALLPADAPARLLEASIAE 130
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 185-342 1.72e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 1.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 185 KATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQ 264
Cdd:TIGR02917 471 LGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEE 550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 265 QALGWLSgyqPDLASNMDYYATWAGLTQ---ELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNA 341
Cdd:TIGR02917 551 EAVAWLE---KAAELNPQEIEPALALAQyylGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKL 627


                  .
gi 1876456502 342 L 342
Cdd:TIGR02917 628 L 628
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 141-270 3.93e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 3.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 141 LQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLA 220
Cdd:COG5010    16 LLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLA 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1876456502 221 GLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWL 270
Cdd:COG5010    96 LLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAAL 145
TPR_19 pfam14559
Tetratricopeptide repeat;
193-256 6.84e-06

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 43.34  E-value: 6.84e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1876456502 193 GSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARL 256
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
184-343 1.06e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 46.15  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 184 RKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQ 263
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 264 QQALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNALL 343
Cdd:COG0457   161 EEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
186-362 2.44e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.38  E-value: 2.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 186 ATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQ 265
Cdd:COG0457    49 GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 266 ALGWLSGYQPDLASNMDYYATWAGLTQELGQNADAAALYVKLLRQqpdQGRWWLGLGVAEDGQGHSQRALDAYRNALLHG 345
Cdd:COG0457   129 AIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA---ALAALLAAALGEAALALAAAEVLLALLLALEQ 205

                         170
                  ....*....|....*..
gi 1876456502 346 NLGEASTNWLEQRIGQL 362
Cdd:COG0457   206 ALRKKLAILTLAALAEL 222
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
222-313 4.95e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.69  E-value: 4.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 222 LLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLSGYQPDlASNMDYYATWAGLTQELGQNADAA 301
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLD-PNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|..
gi 1876456502 302 ALYVKLLRQQPD 313
Cdd:COG3063    80 AYLERALELDPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 186-266 2.34e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.06  E-value: 2.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 186 ATTAMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQ 265
Cdd:COG3914   153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEV 232


                  .
gi 1876456502 266 A 266
Cdd:COG3914   233 Y 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 218-342 2.42e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.41  E-value: 2.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 218 QLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWlsgYQPDLASNMDYYATWAGLTQ---EL 294
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRI---HQKLLERDPDRAEALLELAQdylKA 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1876456502 295 GQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL 342
Cdd:COG2956    90 GLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLL 137
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
62-196 4.08e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.53  E-value: 4.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  62 PVVAASEVVAPDAVTPDVVTRAAAPVSQSEPVEVA----------AALPLPSQDEVNDEAGEGDSGDTADGAPFDASSDV 131
Cdd:PRK07003  402 VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAdrgddaadgdAPVPAKANARASADSRCDERDAQPPADSGSASAPA 481

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1876456502 132 DESEPtDEELQPELYAELAAEQQAVASAPRKPGVLKIETVELSAKELAALAERKATTAMAKGSLR 196
Cdd:PRK07003  482 SDAPP-DAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAAR 545
TPR_19 pfam14559
Tetratricopeptide repeat;
226-290 9.49e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.18  E-value: 9.49e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1876456502 226 EGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLSGYQPDLASNMDYYATWAGL 290
Cdd:pfam14559   1 EGDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 168-342 1.08e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 168 IETVELSAKELAALAERKATTAMAKGSLRDAQDNYYDVLAHDPYNQGAReQLAGLLYGEGRLTEARQLLEEGIRLDPQQA 247
Cdd:TIGR02917 692 AKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTLEAWLKTHPNDA 770

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 248 DFRLLLARLAISEGQQQQAlgwLSGYQPDLASNMDYYATWAGLTQELGQNADAAAL-YV-KLLRQQPDQGRWWLGLGVAE 325
Cdd:TIGR02917 771 VLRTALAELYLAQKDYDKA---IKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRALeYAeRALKLAPNIPAILDTLGWLL 847

                         170
                  ....*....|....*..
gi 1876456502 326 DGQGHSQRALDAYRNAL 342
Cdd:TIGR02917 848 VEKGEADRALPLLRKAV 864
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 190-270 1.13e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 40.37  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 190 MAKGSLRDAQDNYYDVL--------AHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRL----DPQQA-DFRLLLARL 256
Cdd:pfam17874  91 RAQGRLHQALETYQQALqlardhglQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLgrqwEPDAAvDAYVLLARI 170

                          90
                  ....*....|....
gi 1876456502 257 AISEGQQQQALGWL 270
Cdd:pfam17874 171 ALAQGELEEALTLL 184
rne PRK10811
ribonuclease E; Reviewed
 59-191 2.63e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 40.02  E-value: 2.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502   59 QTHPVVAASEVVAPDAVTPDVVTRAAAPVSQSEPVEVAAALPlPSQDEVNDEAGEGDSGDTADGAPFDASSDVDESEPTD 138
Cdd:PRK10811   865 QVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQP-EEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVA 943

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1876456502  139 EELQP--ELYAELAAEQQAVASAP----RKPGVLKIETVELSAKELAALAERKATTAMA 191
Cdd:PRK10811   944 EHAEPvvEPQDETADIEEAAETAEvvvaEPEVVAQPAAPVVAEVAAEVETVTAVEPEVA 1002
rne PRK10811
ribonuclease E; Reviewed
 62-192 2.90e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 39.64  E-value: 2.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502   62 PVVAASEVVAPDAVTPDVVTRAAAPVSQSEPVEVAA-----------ALPLPSQDEVNDEAGEGDSGDTADGA-----PF 125
Cdd:PRK10811   874 PVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVvvvetthpeviAAPVTEQPQVITESDVAVAQEVAEHAepvvePQ 953

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1876456502  126 DASSDVDESEPTDEELQPElyAELAAEQQAVASAPRKPGVLKiETVELSAKELAALAE-----RKATTAMAK 192
Cdd:PRK10811   954 DETADIEEAAETAEVVVAE--PEVVAQPAAPVVAEVAAEVET-VTAVEPEVAPAQVPEatvehNHATAPMTR 1022
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 165-342 4.93e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 4.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 165 VLKIETVELSAKELAALAErkattaMAKGSLRDAQDNYYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDP 244
Cdd:TIGR02917 287 ALKSAPEYLPALLLAGASE------YQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDP 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 245 QQADFRLLLARLAISEGQ----------------------QQQALGWLSGYQP-----DL--ASNMDYYATWAGLTQEL- 294
Cdd:TIGR02917 361 DDPAALSLLGEAYLALGDfekaaeylakateldpenaaarTQLGISKLSQGDPseaiaDLetAAQLDPELGRADLLLILs 440

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1876456502 295 ----GQNADAAALYVKLLRQQPDQGRWWLGLGVAEDGQGHSQRALDAYRNAL 342
Cdd:TIGR02917 441 ylrsGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKAL 492
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 206-344 7.88e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 7.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 206 LAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLLARLAISEGQQQQALGWLSGYQPDLASNMDYYA 285
Cdd:TIGR02917  49 LQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLDDEGAAELL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502 286 TWAGLT------QELGQNADAAAL--------------YVKLLRQQPDQGR---------------WWLGLGVAEDGQGH 330
Cdd:TIGR02917 129 ALRGLAylglgqLELAQKSYEQALaidprslyaklglaQLALAENRFDEARalidevltadpgnvdALLLKGDLLLSLGN 208

                         170
                  ....*....|....
gi 1876456502 331 SQRALDAYRNALLH 344
Cdd:TIGR02917 209 IELALAAYRKAIAL 222
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 176-342 8.04e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 38.14  E-value: 8.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  176 KELAALAERKATTAMAKGsLRDAQDN--YYDVLAHDPYNQGAREQLAGLLYGEGRLTEARQLLEEGIRLDPQQADFRLLL 253
Cdd:PRK11447   565 QELAQRLQSDQVLETANR-LRDSGKEaeAEALLRQQPPSTRIDLTLADWAQQRGDYAAARAAYQRVLTREPGNADARLGL 643

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876456502  254 ARLAISEGQQQQALGWLSgyQPDLASNMDYYA------TWAGLtqelGQNADAAALYVKLLRQQPDQGRWWLGLGVAEDG 327
Cdd:PRK11447   644 IEVDIAQGDLAAARAQLA--KLPATANDSLNTqrrvalAWAAL----GDTAAAQRTFNRLIPQAKSQPPSMESALVLRDA 717

                          170       180
                   ....*....|....*....|.
gi 1876456502  328 ------QGHSQRALDAYRNAL 342
Cdd:PRK11447   718 arfeaqTGQPQQALETYKDAM 738
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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