|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
1-672 |
0e+00 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 1479.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 1 MRLNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGRKETRGLM 80
Cdd:PRK10919 1 MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLGRKEARGLM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 81 IATFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKELTEQWLENDKVLLQQLISTISNWKNDLIDPAGAAATARSER 160
Cdd:PRK10919 81 ISTFHTLGLDIIKREYAALGMKSNFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAGAKGER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 161 DKLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTVV 240
Cdd:PRK10919 161 DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 241 GDDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVITANNE 320
Cdd:PRK10919 241 GDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSANNE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 321 DHEAERVVGELIAHHFIKKTQYGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTNPDDDS 400
Cdd:PRK10919 321 EHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 401 AFLRIVNTPKREIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGLESLQRFTQWLAEIARLAEREPVAAVRDLIH 480
Cdd:PRK10919 401 AFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQTLSGRGYESLTRFTHWLAEIQRLAEREPVAAVRDLIH 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 481 GLDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSDLDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHAS 560
Cdd:PRK10919 481 GIDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHAS 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 561 KGLEFPYVFLVGMEEGLLPHQSSIDEDNVDEERRLAYVGITRAQRELFFTLCKERRQYGELVRPEPSRFLLELPQDDVVW 640
Cdd:PRK10919 561 KGLEFPYVYLVGMEEGLLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIW 640
|
650 660 670
....*....|....*....|....*....|..
gi 1878687111 641 ETERKVVSAQERMQKGQTNVANIRAMLAKAKG 672
Cdd:PRK10919 641 EQERKVVSAEERMQKGQSHLANLKAMLAAKRG 672
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
2-664 |
0e+00 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 1224.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 2 RLNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGRKETRGLMI 81
Cdd:TIGR01074 1 KLNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYLIQNCGYKARNIAAVTFTNKAAREMKERVAKTLGKGEARGLTI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 82 ATFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKELTEQWLENDKVLLQQLISTISNWKNDLIDPAGAAATARSERD 161
Cdd:TIGR01074 81 STFHTLGLDIIKREYNALGYKSNFSLFDETDQLALLKELTEGLIKDDKDLLDKLISTISNWKNDLLTPEQALASARGERE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 162 KLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTVVG 241
Cdd:TIGR01074 161 QTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARFTVVG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 242 DDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVITANNED 321
Cdd:TIGR01074 241 DDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIECNNEE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 322 HEAERVVGELIAHHFIKKTQYGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTNPDDDSA 401
Cdd:TIGR01074 321 HEAERIAGEIIAHKLVNKTQYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRLLVNPDDDAA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 402 FLRIVNTPKREIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGLESLQRFTQWLAEIARLAER-EPVAAVRDLIH 480
Cdd:TIGR01074 401 FLRIVNTPKREIGPATLEKLGELAMERNKSLFTASFDMGLLQTLSGRGYESLQRFTDWLVEIRRLAERsEPIEAVRSLIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 481 GLDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSDLDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHAS 560
Cdd:TIGR01074 481 DIDYENWLYETSPSPKAAEMRMKNVNTLFSWFKEMLEGDEEDEPMTLTQVVTRLTLRDMLERGEDEEELDQVQLMTLHAS 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 561 KGLEFPYVFLVGMEEGLLPHQSSIDEDNVDEERRLAYVGITRAQRELFFTLCKERRQYGELVRPEPSRFLLELPQDDVVW 640
Cdd:TIGR01074 561 KGLEFPYVFIVGMEEGILPHQSSIEEDNVEEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLDELPQEDLQW 640
|
650 660
....*....|....*....|....
gi 1878687111 641 ETERKVVSAQERMQKGQTNVANIR 664
Cdd:TIGR01074 641 EGDDPVVSAEEKMEKGQAHLANLR 664
|
|
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
1-665 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 839.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 1 MRLNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGRKeTRGLM 80
Cdd:COG0210 5 AGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRL-ARGLW 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 81 IATFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKELTEQW-LENDKVLLQQLISTISNWKNDLIDPAGAAAT-ARS 158
Cdd:COG0210 84 VGTFHSLALRILRRHAELLGLPPNFTILDGDDQLRLIKELLKELgLDEKRFPPRELLSLISRAKNEGLTPEELAELlAAD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 159 ERDKLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFT 238
Cdd:COG0210 164 PEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRNLC 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 239 VVGDDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVITAN 318
Cdd:COG0210 244 VVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYVAP 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 319 NEDHEAERVVGELIAHHFiKKTQYGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTNPDD 398
Cdd:COG0210 324 DEEEEARFVADEIRELHE-EGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYLRLLANPDD 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 399 DSAFLRIVNTPKREIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGLESLQRFTQWLAEIARLAEREPVA-AVRD 477
Cdd:COG0210 403 DVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDLGELAGLSGRAAKALRRFAELLEALRAAAERLPLEeLLEA 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 478 LIHGLDYESWLYETspSPKAAEMRMKNVNQLFSWMTEMLEGsdlDEPMTLTQVVTRFTLRDMMERGESEEelDQVQLMTL 557
Cdd:COG0210 483 LLDESGYEEELREE--AGEEAERRLENLEELVDAAARFEER---NPGASLEAFLEELALLSDLDAADEDE--DAVTLMTL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 558 HASKGLEFPYVFLVGMEEGLLPHQSSI-DEDNVDEERRLAYVGITRAQRELFFTLCKERRQYGELVRPEPSRFLLELPQD 636
Cdd:COG0210 556 HAAKGLEFPVVFLVGLEEGLFPHQRSLdDEEELEEERRLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELPEE 635
|
650 660
....*....|....*....|....*....
gi 1878687111 637 DVVWETERKVVSAQERMQKGQTNVANIRA 665
Cdd:COG0210 636 LLEWVRPKAEAAAAAASAAAALPASGAGA 664
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
3-645 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 612.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 3 LNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGrKETRGLMIA 82
Cdd:TIGR01073 5 LNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLG-PVAEDIWIS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 83 TFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKE-LTEQWLENDKVLLQQLISTISNWKNDLIDPAGAAATARSERD 161
Cdd:TIGR01073 84 TFHSMCVRILRRDIDRIGINRNFSIIDPTDQLSLMKTiLKDKNLDPKKFEPRSILGTISNAKNELLPPEDFAKEATNYFE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 162 KLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTVVG 241
Cdd:TIGR01073 164 KVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRFRNLCVVG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 242 DDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVITANNED 321
Cdd:TIGR01073 244 DADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITYYEADTER 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 322 HEAERVVGELIAHHFIKKTQYGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTNPDDDSA 401
Cdd:TIGR01073 324 DEAQFVAGEIDKLVKNGERKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLRVIANPDDDLS 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 402 FLRIVNTPKREIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGLESLQRFTQWLAEIARLAEREPVAAVRDLIhg 481
Cdd:TIGR01073 404 LLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEIDEIGGLAAKSANALLAFATMIENLRQQQEYLSPTELVEEV-- 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 482 LDYESWL----YETSPSpkaAEMRMKNVNQLfswMTEMLEGSDLDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTL 557
Cdd:TIGR01073 482 LDKSGYRemlkAEKTEE---AQSRLENLDEF---LSVTKEFEDESEDKSLIDFLTDLALVSDLDELEETEEGGAVTLMTL 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 558 HASKGLEFPYVFLVGMEEGLLPHQSSI-DEDNVDEERRLAYVGITRAQRELFFTLCKERRQYGELVRPEPSRFLLELPQD 636
Cdd:TIGR01073 556 HAAKGLEFPVVFLIGMEEGVFPHSRSLmDEKELEEERRLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLNEIPAE 635
|
....*....
gi 1878687111 637 DVVWETERK 645
Cdd:TIGR01073 636 LLETASTGR 644
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
3-636 |
1.29e-169 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 502.48 E-value: 1.29e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 3 LNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGRKeTRGLMIA 82
Cdd:PRK11773 10 LNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGTS-QGGMWVG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 83 TFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKEL-TEQWLENDKVLLQQLISTISNWKND-----LIDPAGAAATa 156
Cdd:PRK11773 89 TFHGLAHRLLRAHWQDANLPQDFQILDSDDQLRLLKRLiKALNLDEKQWPPRQAQWYINGQKDEglrpqHIQSYGDPVE- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 157 rserdKLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRAR 236
Cdd:PRK11773 168 -----QTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDTGK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 237 FTVVGDDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVIT 316
Cdd:PRK11773 243 VMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISLYC 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 317 ANNEDHEAERVVGEliahhfIKKTQ-----YGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLR 391
Cdd:PRK11773 323 AFNELDEARFVVER------IKTWQdnggaLSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLR 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 392 VLTNPDDDSAFLRIVNTPKREIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGLESLQRFTQWLAEIARLAEREP 471
Cdd:PRK11773 397 LIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKVLAGRAASALQRFIELIDALAQETADMP 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 472 VAAVRDLI---HGLdYEswLYETSPSPKaAEMRMKNVNQLFSwMTEMLEGSDLDEPMT-LTQVVTRFTLrdmmERGES-- 545
Cdd:PRK11773 477 LHEQTDRVikdSGL-RA--MYEQEKGEK-GQARIENLEELVT-ATRQFSYPDEDEDLTpLQAFLSHAAL----EAGEGqa 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 546 EEELDQVQLMTLHASKGLEFPYVFLVGMEEGLLPHQSSIDE-DNVDEERRLAYVGITRAQRELFFTLCKERRQYGELVRP 624
Cdd:PRK11773 548 DAHEDAVQLMTLHSAKGLEFPLVFIVGMEEGLFPSQMSLEEgGRLEEERRLAYVGITRAMQKLTLTYAESRRLYGKEVYH 627
|
650
....*....|..
gi 1878687111 625 EPSRFLLELPQD 636
Cdd:PRK11773 628 RPSRFIREIPEE 639
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
3-658 |
2.76e-158 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 473.14 E-value: 2.76e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 3 LNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGrKETRGLMIA 82
Cdd:TIGR01075 5 LNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLG-TSARGMWIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 83 TFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKELTEQWLENDKVLL-QQLISTISNWKNDLIDPAGAAA-TARSER 160
Cdd:TIGR01075 84 TFHGLAHRLLRAHHLDAGLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPpRQAMWYINNQKDEGLRPSHIQAfDNPVER 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 161 DklFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTVV 240
Cdd:TIGR01075 164 T--WIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGNVMIV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 241 GDDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVITANNE 320
Cdd:TIGR01075 242 GDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYSAFNE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 321 DHEAERVVGEliahhfIKKTQ-----YGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTN 395
Cdd:TIGR01075 322 LDEARFVVSR------IKTWQrnggaLDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIAN 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 396 PDDDSAFLRIVNTPKREIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGLESLQRFTQWLAEIARLAEREPVAAV 475
Cdd:TIGR01075 396 RNDDAAFERVINTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEKVLAGRAASALQRFVELIEALANETADMPLHVQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 476 RDLI---HGLdYEswLYETSPSPKaAEMRMKNVNQLFSWMTEMLEGSDLDEPMTLTQVVTRFTLrdmmERGE--SEEELD 550
Cdd:TIGR01075 476 TDHVikdSGL-RE--MYQQEKGEK-GQARIENLEELVTATRQFSLPENDEDMTPLTAFLSHAAL----EAGEgqADAGQD 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 551 QVQLMTLHASKGLEFPYVFLVGMEEGLLPHQSSIDE-DNVDEERRLAYVGITRAQRELFFTLCKERRQYGELVRPEPSRF 629
Cdd:TIGR01075 548 AVQLMTLHSAKGLEFPLVFLVGMEEGMFPSQMSLDEgGRLEEERRLAYVGITRAMQKLTITYAETRRLYGKEVYHIPSRF 627
|
650 660
....*....|....*....|....*....
gi 1878687111 630 LLELPQDDVVWETERKVVSAQERMQKGQT 658
Cdd:TIGR01075 628 IRELPEECLHEVRLRAQVSRPTNLGRVGT 656
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
3-266 |
1.05e-108 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 329.59 E-value: 1.05e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 3 LNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGRKETRGLMIA 82
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGKAELSELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 83 TFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKELTEQ-WLENDKVLLQQ--LISTISNWKNDLIDPAGAAATARSE 159
Cdd:pfam00580 81 TFHSFCLRILRKYANRIGLLPNFSILDELDQLALLKELLEKdRLNLDPKLLRKleLKELISKAKNRLLSPEELQQGAADP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 160 RDKLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTV 239
Cdd:pfam00580 161 RDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENLFL 240
|
250 260
....*....|....*....|....*..
gi 1878687111 240 VGDDDQSIYSWRGARPQNLVLLQQDFP 266
Cdd:pfam00580 241 VGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
1-617 |
1.57e-92 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 305.73 E-value: 1.57e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 1 MRLNPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGR------- 73
Cdd:COG1074 4 PPWTDAQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIRERLAEaadledp 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 74 -KETR---------------GLMIATFHTLGLEIIKREYVALGMKSNFSLFDDQDQMAL-------------------LK 118
Cdd:COG1074 84 dLEELararrrlaralenldRAAISTIHSFCQRLLREFAFEAGLDPNFELLDDAEALLLeeavddllreayapldalaLA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 119 ELTEQWLENDKVL-------------------LQQLISTISNWKNDLIDPAGAAATARSERD-----------KLFVHCY 168
Cdd:COG1074 164 RLLDAFGRDDDSLeelllalyklrsrpdwleeLAELDEALEALREALLKAKEALAALREALAaaaapllaallRLLAAVL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 169 SLYHDHLRACNVLDFDDLILLPTLLLKQN--AEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVG----TRARFTVVGD 242
Cdd:COG1074 244 ARYERRKRERGLLDFDDLLHRALRLLRDEdaPWVAERLRERYRHILVDEFQDTSPLQWEILRRLAGealaDGRTLFLVGD 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 243 DDQSIYSWRGARPQNLVLLQQDFPA---LDVIKLEQNYRSSGRILKAANiliannpHVFEKRL---FSELGYGD------ 310
Cdd:COG1074 324 PKQSIYRFRGADPELFLEARRALEGrvdGERLTLTTNFRSTPEVVDAVN-------ALFAQLMgagFGEIPYEPvealrp 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 311 ------ELKVITANNE------DHEAERVVGE----LIAHHFIKKT----QYGDYAILYRGNHQARLFEKMLMQNRIPYR 370
Cdd:COG1074 397 gaypavELWPLEPDDVseedarEREARAVAARirrlLAEGTTVEGGgrpvRPGDIAVLVRTRSEAAAIARALKAAGIPVA 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 371 ISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPkreIGPATMKKLGEWAGQRNKGLFSASFdlglsqtltgRGL 450
Cdd:COG1074 477 ASDRLSLFESPEVRDLLALLRALLNPEDDLALAAVLRSP---LFGLSDEDLAALAADRKGESLWEAL----------RAY 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 451 ESLQRFTQWLAEIARLAEREPVAA-VRDLIHGLDYESWLYETSpspkAAEMRMKNVNQLFSWMtEMLEGSDLDEPMTLTQ 529
Cdd:COG1074 544 ERLARALERLRALRELARRLGLAElLERLLEETGLLERLLALP----GGERRLANLLHLDELL-QLALEYEQTGGPGLAG 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 530 VVTRftLRDMMERGESEEEL------DQVQLMTLHASKGLEFPYVFLVgmeegllPHQSSIDEDNVDEERRLAYVGITRA 603
Cdd:COG1074 619 FLRW--LERLIEDGGDEEKRrlesdaDAVRIMTIHKSKGLEFPVVFLP-------ALRERARAEELAEELRLLYVALTRA 689
|
730
....*....|....
gi 1878687111 604 QRELFFTLCKERRQ 617
Cdd:COG1074 690 RDRLVLSGAVKKKD 703
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
271-614 |
4.74e-81 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 261.57 E-value: 4.74e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 271 IKLEQNYRSSGRILKAANILIANNPHV----FEKRLFSELGYGDELKVITANNEDHEAERVVGELIAHHFiKKTQYGDYA 346
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRatiyPKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVA-RDEKYNDIA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 347 ILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATMKKLGEwag 426
Cdd:pfam13361 80 VLTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIRE--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 427 QRNKGLFSASFDLGLSQTLTGRGLESLQR------------FTQWLAEIARLAE-------------------REPVAAV 475
Cdd:pfam13361 157 YKKRGLRLSDFINPDTLTYGDPFVIALEQdnivvfdvettgLDTTEDEIIQIAAiklnkkgvviesferflrlKKPVGDS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 476 RDLIHGLDYESWLYETSPSPKAAEM--RMKNVNQLFSWMTEMLEGSDLDEPMT-LTQVVTRFTLRDMMERGESEEEldQV 552
Cdd:pfam13361 237 LQVHGFSDEFLQENGETPAEALRDFleKLENLRELYSILREYDDIEETPEPEDaLRNFLEIATLSNSELEGSDIKE--RI 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1878687111 553 QLMTLHASKGLEFPYVFLVGMEEGLLPHQ-SSIDEDNVDEERRLAYVGITRAQRELFFTLCKE 614
Cdd:pfam13361 315 PIMTIHQAKGLEFDTVFLAGLEEGIFPSYrSIKDEGNLEEERRLFYVAITRAKKRLYISYSKS 377
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
4-277 |
9.89e-77 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 243.58 E-value: 9.89e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 4 NPSQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGRKETRGLMIAT 83
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEQLASGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 84 FHTLGLEIIKREYvalgmksnfslfDDQDQMALLKELTEQwlendkvllqqlistisnwkndlidpagaaatarserdkl 163
Cdd:cd17932 81 FHSFALRILRRYG------------DFDDLLLYALELLEE---------------------------------------- 108
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 164 fvhcyslyhdhlracnvldfddlillptlllkqNAEVRERWQNRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTVVGDD 243
Cdd:cd17932 109 ---------------------------------NPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDD 155
|
250 260 270
....*....|....*....|....*....|....
gi 1878687111 244 DQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNY 277
Cdd:cd17932 156 DQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
5-608 |
5.24e-33 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 136.37 E-value: 5.24e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 5 PSQQHAVeFVTGP-CLVLAGAGSGKTRVITNKIAHLIRQcGYQAKHIAAVTFTNKAAREMKERVA--------QTLGRKE 75
Cdd:TIGR02785 4 DEQWQAI-YTRGQdILVSASAGSGKTAVLVERIIRKITR-GVDVDRLLVVTFTNAAAREMKERIAealekelvQEPNSKH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 76 TRGLM-------IATFHTLGLEIIKREYVALGMKSNFSLFDDQDQMALLKE--------------------LTEQ----- 123
Cdd:TIGR02785 82 LRRQLallntanISTLHSFCLKVIRKHYYLLDLDPSFRILTDTEQLLLIKEvlddvfeeeyykedkeaffeLVDNfsgdr 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 124 ------------------------WLEN--------------DKVLLQQLISTISN------------------------ 141
Cdd:TIGR02785 162 sddglrdlilqlydfsrstpnpekWLNNlaeayevkekftieSLKLQQQIKELLKNeleglqeklqralelfmaedglap 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 142 --------------------------------------------WKNDLIDPAGAAATARSERDKLFVHCYSLY-----H 172
Cdd:TIGR02785 242 rlenfqldlqnideliqeslaqadwnelrkavaafkfknlkaakGDEEDADLLEEADKLREEAKKQLEKLKTDYftrseE 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 173 DHLRAC----------------------------NVLDFDDLI----LLPTLLLKQNAEVRERWQNRLRYLLVDEYQDTN 220
Cdd:TIGR02785 322 DHLRIMqemkpvvktlvqlvkdfierfgaekrekNILDFSDLEhyalQILTNENESPSEAAEFYREKFHEVLVDEYQDTN 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 221 TSQYELIKLLV----GTRARFtVVGDDDQSIYSWRGARPQNLVLLQQDFPALD-----VIKLEQNYRSSGRILKAANili 291
Cdd:TIGR02785 402 LVQESILQLVKrgpeEEGNLF-MVGDVKQSIYRFRQADPLLFLEKYHRFAQEGeehgkRIDLAENFRSRAEVLDTTN--- 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 292 annpHVFEKRLFSELG---YGDELKVI-----------------------TANNEDH--------------EAERVVGE- 330
Cdd:TIGR02785 478 ----FLFKQLMDEEVGeidYDEEAQLKfgaakypenpdnkteellyekllIEEAEEEeideeaeildkaqqEATMVAERi 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 331 --LIAHHF---------IKKTQYGDYAILYRGNHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLTNPDDD 399
Cdd:TIGR02785 554 kaLIKEGFkvydkktgtYRPVTYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQD 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 400 SAFLRIVNTPkreIGPATMKKLGEWAGQRNKGLFSASFDLGLSQTLTGRGL-ESLQRFTQWLAEIARLAEREPVAavrDL 478
Cdd:TIGR02785 634 IPLVAVLRSP---IVGFDENELALIRLENKDSSYYEAVKDYVKAGLIEDELyEKLNTFLDSLQKWREFARTHSVS---EL 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 479 IHGLDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSDldepMTLTQVVtRFtLRDMMERGE-------SEEELDQ 551
Cdd:TIGR02785 708 IWKIYNDTGYYDYVGGLPGGKQRQANLYALYERARQYESTSF----KGLFQFI-RF-IERMQERQKdlasavaVGEAENA 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 552 VQLMTLHASKGLEFPYVFLVGM----------EEGLLPHQSSIDEDNVD-------------------------EERRLA 596
Cdd:TIGR02785 782 VRLMTIHKSKGLEFPVVFVLGMgkqfnkqdlnSSYLLDRQLGLGIKYIDpqerlsypslpkvaikqkmkrellsEEMRVL 861
|
890
....*....|..
gi 1878687111 597 YVGITRAQRELF 608
Cdd:TIGR02785 862 YVALTRAKEKLI 873
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
12-635 |
4.84e-29 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 123.70 E-value: 4.84e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 12 EFVTGPclvlagAGSGKTRVITNKIAHLIRQcgyqaKHIAAVTFTNKAAREMKERVAQTLGRKETRGLMIATFHTLGLEI 91
Cdd:COG3857 1 RFILGR------AGSGKTTYLLEEIKEELKE-----GKPIILLVPEQMTFQAERALLKRLGLGGSIRAQVLSFSRLAWRV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 92 IKReyvaLGMKSNFSLFDDQDQMAL---LKELTEQW-----LENDKVLLQQLISTISNWKNDLIDPAGAAATARSERDKL 163
Cdd:COG3857 70 LQE----TGGATRPLLSDAGKRMLLrkiLEEHKDELkvfarAADKPGFIEQLAELITELKRYGITPEDLEEAAELLKEKL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 164 --FVHCYSLYHDHLRAcNVLDFDDLILLPTLLLKQNAEVRERwqnrlrYLLVDEYQDTNTSQYELIKLLVGTRARFTV-- 239
Cdd:COG3857 146 rdLALIYEAYEEKLAG-RYIDSEDLLRLLAEKLEKSEFLEGA------EIYIDGFTDFTPQELELLEALLKKAKEVTItl 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 240 -VGDDDQSIYS---------WRGARPQNLVLLQQDFPALDviKLEQNYRSSGRILKAANIliannphvfekrlfselgyg 309
Cdd:COG3857 219 tLDPDELDLFSatgetyerlLELAKENGVEVEFKKSPELA--HLERNLFAYPPEEEPEGI-------------------- 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 310 delKVITANNEDHEAERVVGELIAHHFIKKTQYGDYAILYRG-NHQARLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLA 388
Cdd:COG3857 277 ---EIIEAANRRAEVEAVAREIRRLVREEGYRYRDIAVVVRDlEAYAPLIERVFAEYGIPYFIDEKRPLSHHPLVELILS 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 389 YLRVLTNPDDDSAFLRIVNTP-KREIGPATMKKLGEW---AGQRNKGLFSASFDLGLSQTLTGRG-LESLQRFTQWLAE- 462
Cdd:COG3857 354 LLELVRSNFRYEDVFRLLKTGlLRPLSREEIDRLENYvlaYGIRGRRWLERYLEEEEELTDEEEEdLERLNELRDRLLEp 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 463 IARLAE--------REPVAAVRDLIHGLDYESWLYETSPSPKAAEMRMKN-----VNQLFSWMTEMLEGSDlDEPMTLTQ 529
Cdd:COG3857 434 LLPLRErlkkaktvREWAEALYEFLEELGVPEKLEEWREAEEAGDLEEAReheqaWNALIELLDELVEVLG-DEKLSLEE 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 530 VVTrfTLRDMMER---GESEEELDQVQLMTLHASKGLEFPYVFLVGMEEGLLP---HQSSI------------------- 584
Cdd:COG3857 513 FLR--ILESGLEEltfGLIPPSLDQVQVGGLDRARGLDFKAVFVLGLNEGVFParpREDGLlsdeererlnelglelppt 590
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 1878687111 585 DEDNVDEERRLAYVGITRAQRELFFTLCKERRQYGELvrpEPSRFLLELPQ 635
Cdd:COG3857 591 SRERLLEERFLFYRALTRASERLYLSYPLADEEGKAL---LPSPLIDRLRE 638
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
279-610 |
1.51e-28 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 111.55 E-value: 1.51e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 279 SSGRILKAANILIANNPHVFEKRLFSELGYGDELKVITANNEDHEAERVVGELIAHHFIKKTQYGDYAILYRGNHQARLF 358
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGPVQYSDIAILVRTNRQARVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 359 EKMLMqnripyrisggtsffsrpeikdllaylrvltnpdddsaflrivntpkreigpatmkklgewagqrnkglfsasfd 438
Cdd:cd18807 81 EEALR--------------------------------------------------------------------------- 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 439 lglsqtltgrgleslqrftqwlaeiarlaerepvaavrdlihgldyeswlyetspspkaaemrmknvnqlfswmtemleg 518
Cdd:cd18807 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 519 sdldepmtltqvvtrftlrdmmergeseeeldqVQLMTLHASKGLEFPYVFLVGMEEGLLPHQSS-----IDEDNVDEER 593
Cdd:cd18807 86 ---------------------------------VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASyhaakEDEERLEEER 132
|
330
....*....|....*..
gi 1878687111 594 RLAYVGITRAQRELFFT 610
Cdd:cd18807 133 RLLYVALTRAKKELYLV 149
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
3-325 |
1.55e-28 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 121.60 E-value: 1.55e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 3 LNPSQQHAVefVTGP--CLVLAGAGSGKTRVITNKIAHLIRQCGYQAKHIAAVTFTNKAAREMKERVAQTLGrkeTRGLM 80
Cdd:PRK11054 197 LNPSQARAV--VNGEdsLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDERIRERLG---TEDIT 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 81 IATFHTLGLEIIKR-EYVALGMkSNFSLFDDQDQMALLKELTEQ-------------WLE-------------NDKVLLQ 133
Cdd:PRK11054 272 ARTFHALALHIIQQgSKKVPVI-SKLENDSKARHALLIAEWRKQcsekkaqakgwrqWLTeelqwdvpegnfwDDEKLQR 350
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 134 QLISTISNW----------KNDLIDPAGAAATAR-SERDKLFVHCYSLYHDHLRACNVLDFDDLILLPTLLLKQNAEVRE 202
Cdd:PRK11054 351 RLASRLERWvslmrmhggsQAEMIAQAPEEVRDLfQKRLKLMAPLLKAWKKALKAENAVDFSGLIHQAVNYLEKGRFISP 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 203 rWqnrlRYLLVDEYQDTNTSQYELIKLLVGTRARFTV--VGDDDQSIYSWRGArpqNLVL---LQQDFPALDVIKLEQNY 277
Cdd:PRK11054 431 -W----KHILVDEFQDISPQRAALLAALRKQNSQTTLfaVGDDWQAIYRFSGA---DLSLttaFHERFGEGDRCHLDTTY 502
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1878687111 278 RSSGRILKAANILIANNPHVFEKRLFSeLGYGDELKVITANNEDHEAE 325
Cdd:PRK11054 503 RFNSRIGEVANRFIQQNPHQLKKPLNS-LTKGDKKAVTLLPEDQLEAL 549
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
171-621 |
1.05e-18 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 90.90 E-value: 1.05e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 171 YHDHLRACNVLDFDDLILLPTLLLKQNAE---VRERWQNRLRYLLVDEYQDTNTSQYELIKLL-----VGTRAR------ 236
Cdd:TIGR02784 351 YARLKKARGLLDFNDLIERTVALLARPGAgawVHYKLDRGIDHILVDEAQDTSPEQWDIIQALaeeffSGEGARsgvert 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 237 -FtVVGDDDQSIYSWRGARPQNLVLLQQDFPA--------LDVIKLEQNYRSSGRILKA-----ANI-----LIANNPHV 297
Cdd:TIGR02784 431 iF-AVGDEKQSIYSFQGADPERFAEERREFSRkvravgrkFEDLSLNYSFRSTPDVLAAvdlvfADPenargLSADSDAP 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 298 FEKRLFSELGYGDEL-----KVITANNE------DHE---------AERVVGElIAHHFIKKTQ---------YGDYAIL 348
Cdd:TIGR02784 510 VHEAFRDDLPGRVDLwdlisKEEGEEPEdwtdpvDELgerapevrlAERIAAE-IRAWLDRGTPipgrgravrPGDILVL 588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 349 YRgnHQARLFEKM---LMQNRIPyrISGG-----TSFFSrpeIKDLLAYLRVLTNPDDDSAFLRIVNTPkreigpatmkk 420
Cdd:TIGR02784 589 VR--KRDAFFSALiraLKRRGIP--VAGAdrlklTSHIA---VKDLMALGRFVLQPEDDLSLAALLKSP----------- 650
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 421 LGEWAGQRnkgLFSasfdlgLSQTLTGRGL-ESLQRFTQWLAEIARLAEREPVAAVRDLIHGLdYESWLyetspspKAAE 499
Cdd:TIGR02784 651 LFGLDEDD---LFR------LAAGRSGGSLwAALRRREAEFAATLAVLRDWLSLADFLTPFEF-YARLL-------GRDG 713
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 500 MRMKNVNQLFSwmtemlEGSD-LDEPMTLTQVVTRFTLRDM------MERG------ESEEELDQVQLMTLHASKGLEFP 566
Cdd:TIGR02784 714 GRRKLLARLGA------EAEDiLDEFLSQALAYERTGLPGLqaflswLEADdpeikrEMDQARDEVRVMTVHGAKGLEAP 787
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 567 YVFLV-------------------GMEEGLLPHQSSIDEDN--------------VDEERRLAYVGITRAQRELFFTLCK 613
Cdd:TIGR02784 788 VVFLVdtgskpfasqraplllatgGSGGKAPLWRPASAFDPslsaaarerlkeraEDEYRRLLYVAMTRAEDRLIVCGYR 867
|
....*...
gi 1878687111 614 ERRQYGEL 621
Cdd:TIGR02784 868 GKRESPKD 875
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
529-610 |
1.36e-15 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 72.47 E-value: 1.36e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 529 QVVTRF------TLRDMMERGESEEELDQVQLMTLHASKGLEFPYVFLVGMEEGllphqssidednvDEERRLAYVGITR 602
Cdd:cd18786 14 VVLTPYhrdrayLNQYLQGLSLDEFDLQLVGAITIDSSQGLTFDVVTLYLPTAN-------------SLTPRRLYVALTR 80
|
....*...
gi 1878687111 603 AQRELFFT 610
Cdd:cd18786 81 ARKRLVIY 88
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
7-251 |
7.78e-15 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 71.87 E-value: 7.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 7 QQHAVE--FVTGPCLVLAGAGSGKTRVITNKIAHLIRqCGYQAKHIAAVTFTNKAAREMKERVaqtlgrketrGLMIATF 84
Cdd:pfam13245 1 QREAVRtaLPSKVVLLTGGPGTGKTTTIRHIVALLVA-LGGVSFPILLAAPTGRAAKRLSERT----------GLPASTI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 85 HTLgleiikreyvalgmksnfslfddqdqmallkelteqwlendkvllqqlistisnwkndlidpagaaatarserdklf 164
Cdd:pfam13245 70 HRL----------------------------------------------------------------------------- 72
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 165 vhcyslyhdhlracnvLDFDDLILLPTLLLKQNAEVRErwqnrlrYLLVDEYQDTNT-SQYELIKLLVgTRARFTVVGDD 243
Cdd:pfam13245 73 ----------------LGFDDLEAGGFLRDEEEPLDGD-------LLIVDEFSMVDLpLAYRLLKALP-DGAQLLLVGDP 128
|
....*...
gi 1878687111 244 DQSIYSWR 251
Cdd:pfam13245 129 DQLPSVGP 136
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
206-277 |
2.85e-14 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 69.82 E-value: 2.85e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1878687111 206 NRLRYLLVDEYQDTNTSQYELIKLLVGTRARFTVVGDDDQSIYSWRGARPQNLVLLQQ-----DFPALDVIKLEQNY 277
Cdd:cd17914 45 AQLDNILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAVLAKICNEQSlftrlVRLGVSLIRLQVQY 121
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
22-608 |
6.16e-14 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 75.39 E-value: 6.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 22 AGAGSGKTRVITNK-IAHLIRqcGYQAKHIAAVTFTNKAAREMKERVAQT---LGRKETRGLMIATFHTLGL---EII-K 93
Cdd:PRK13909 5 ASAGSGKTFALSVRfLALLFK--GANPSEILALTFTKKAANEMKERIIDTllnLEKEKEESELNELEEKLGLskeELLnK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 94 REYVA---------------------------LGMKSNFSLFDDQDQMA---LLKELTEQ----------WLENDKV--- 130
Cdd:PRK13909 83 RDKVYqeflnselkistidaffqkilrkfclnLGLSPDFSIKEDTKEELnekFLSALSKEellellafikQCESKKNnsf 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 131 --LLQQLI---STISNWKNDLIDPA---------------------GAAATAR--------------------------- 157
Cdd:PRK13909 163 feLLEKLYeknNELKLFEKAKNPIEfdeekfleelrslkqqiqsieTASKNAKkafkkedfeellnssktwlekeseyry 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 158 ----------SERDKL---------------FVHCYSLY-------HDHLRACNVLDFDDLILLPTLLLKQNAEVRE--- 202
Cdd:PRK13909 243 fkklyneeldAEFEELknalkryydakenykLSKLFKLLqlykeakNELNKKKNALDFDDISKKVYELLGEEEIDKDfly 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 203 -RWQNRLRYLLVDEYQDTNTSQYELIKLLV----------GTRARFtVVGDDDQSIYSWRGARPQNLVLLQQDFPaLDVI 271
Cdd:PRK13909 323 fRLDSKISHILIDEFQDTSVLQYKILLPLIdeiksgegqkKFRSFF-YVGDVKQSIYRFRGGKKELFDKVSKDFK-QKVD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 272 KLEQNYRSSGRILKAAN-ILIANNPHVFEKRLFS--ELGYgdeLKVITANNEDHE-AERV---VGELIAHHfikkTQYGD 344
Cdd:PRK13909 401 NLDTNYRSAPLIVDFVNeVFKKKYKNYKTQYAEQhkSGGY---VEVVEVADESEElLEQLlqeIQFLLEKG----IDPDD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 345 YAILYRGNHQA-RLFEKMLMQNRIPYRISGGTSFFSRPEIKDLLAYLRVLtnpdddsaflrivntpkreigpatmkklge 423
Cdd:PRK13909 474 IAILCWTNDDAlEIKEFLQEQFGIKAVTESSAKLINQPEVKALIEALKYC------------------------------ 523
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 424 wagqrnkgLFSASFDLGLSQTLTGrglESLQRFTQWLaeiarLAEREPVAAVRDLIH--GLDYESWL--YETSpspkaae 499
Cdd:PRK13909 524 --------LFGEEIYKHNVLKLLG---KEPDKIPSFL-----PKEESVAEFVKKLIEelKLYDENLLkfLELA------- 580
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 500 MRMKNVNqlfswmtEMLEGSD-LDEPMtltqvvtrftlrdmmergeSEEELDQVQLMTLHASKGLEFPYVFLVGM----- 573
Cdd:PRK13909 581 SGYEDIE-------EFLFKLEpCDKEI-------------------ASEESKGVQIMTVHKSKGLEFEHVIVCDRlgkpn 634
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1878687111 574 --EEGLLPHQSSIDED----------NVDEERRLA----------------YVGITRAQRELF 608
Cdd:PRK13909 635 sdSSNLLFEYDGIELWqiyyrikgreNFDKDYARAlekekalkyeeeinvlYVAFTRAKNSLI 697
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
209-331 |
4.50e-13 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 72.59 E-value: 4.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 209 RYLLVDEYQDTNTSQYELIKLLVGTRaRFTVVGDDDQSIYSWRGARPQNLVLLQQDFPALDVIKLEQNYRSSGRILKAAN 288
Cdd:COG3973 471 GHVVVDEAQDLSPMQWRVLKRRFPSA-SFTIVGDLAQAIHPYRGAESWEEVLEPLGGDRARLVELTKSYRSTAEIMEFAN 549
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1878687111 289 -ILIANNPHVFEKRLFSELgyGDELKVITANNEDHEAERVVGEL 331
Cdd:COG3973 550 rVLRAAGPDLPPPESVRRH--GEPPRVVRVPSEAELAAAVVEAV 591
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
7-376 |
2.53e-10 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 63.31 E-value: 2.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 7 QQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRQcgYQAKHIAAVTFTNKAAREMKERVAQTLGR----KETRGLMIA 82
Cdd:COG3972 165 ERIARSIPDGPQRIRGVAGSGKTVLLAAKAAYLALK--HPGWRILVTCFNRSLADHLRDLIPRFLRRfsngEPEDNVKLI 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 83 TFHTLGLEIIKReyvaLGMKSNFSLFDDQDQMALLKELTEQwlendkvllqqlistisnwkndlidpagaaATARSERDK 162
Cdd:COG3972 243 VFHAWGGKLLKQ----YGIPPLTFSQPNEAFDEACKALLEA------------------------------IQGEIIPPI 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 163 lfvhcyslyhdhlracnvldFDdlillptlllkqnaevrerwqnrlrYLLVDEYQDTNTSQYELI-KLLVGTRARFTVVG 241
Cdd:COG3972 289 --------------------YD-------------------------AILIDEAQDFEPEFLRLLyQLLKPPKKRLIWAY 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 242 DDDQSIYSwrgaRPQNLVLLQQDFPALDVIkLEQNYRSSGRILKAAN----------ILIANNP----------HVFEKR 301
Cdd:COG3972 324 DEAQNIYG----RKIPSAGGIPAGIGRDTI-LKKNYRNTRPILTFAHafgmgllrppGLLQGDAedyeverpgdKVTLIR 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 302 LFSELGY-GDELKVITANNEDHEAERVVGELIahHFIK--KTQYGDYAILYRGNHQARLFE----KMLMQNRIPYRISGG 374
Cdd:COG3972 399 PPEPAGRkGPLPEFKKYDDRAEELEAIAEEIK--KNLRdeGLRPSDIAVIYLGNNEAKELGdrlaAALERQGIDSYIAGA 476
|
..
gi 1878687111 375 TS 376
Cdd:COG3972 477 RS 478
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
555-608 |
1.20e-08 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 51.42 E-value: 1.20e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1878687111 555 MTLHASKGLEFPYVFLVGMEEGllphqssiDEDNVDEERRLAYVGITRAQRELF 608
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLVDPDLT--------AHYHSMLRRRLLYTAVTRARKKLV 50
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
545-629 |
7.28e-07 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 52.29 E-value: 7.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 545 SEEELDQVQL---MTLHASKGLEFPYVFLVgmeeglLPHQSSIDEDnvdeeRRLAYVGITRAQRELffTLCKERRQYGEL 621
Cdd:COG0507 432 DPSELDQLELayaITVHKSQGSTFDRVILV------LPSEHSPLLS-----RELLYTALTRARELL--TLVGDRDALARA 498
|
....*...
gi 1878687111 622 VRPEPSRF 629
Cdd:COG0507 499 VRRDTARA 506
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
1-73 |
1.44e-06 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 51.13 E-value: 1.44e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1878687111 1 MRLNPSQQHAVEFV--TGPCLVLAG-AGSGKTRVItNKIAHLIRQCGYQakhIAAVTFTNKAAREMKERV---AQTLGR 73
Cdd:COG0507 123 ITLSDEQREAVALAltTRRVSVLTGgAGTGKTTTL-RALLAALEALGLR---VALAAPTGKAAKRLSESTgieARTIHR 197
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
18-97 |
1.53e-06 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 46.36 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 18 CLVLAGAGSGKTRVITNKIAHLIRqcgyQAKHIAAVTFTNKAAREMK---ERVAQTLGrkETRGLMIATFHTLGLEIIKR 94
Cdd:cd17912 2 ILHLGPTGSGKTLVAIQKIASAMS----SGKSVLVVTPTKLLAHEILiviDEIQ*ILD--PAAGWAWATRALLGLKAEKV 75
|
...
gi 1878687111 95 EYV 97
Cdd:cd17912 76 IGV 78
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
555-609 |
3.21e-05 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 42.55 E-value: 3.21e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 1878687111 555 MTLHASKGLEFPYVFLVgmeegllphqssIDEDNVDEERRLAYVGITRAQRELFF 609
Cdd:cd18809 36 MTIHKSQGSEFDRVIVV------------LPTSHPMLSRGLLYTALTRARKLLTL 78
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
2-73 |
2.19e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 42.55 E-value: 2.19e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1878687111 2 RLNPSQQHAVE-FVTGP---CLVLAGAGSGKTRVItNKIAHLIRQCGYQakhIAAVTFTNKAAREMKERV---AQTLGR 73
Cdd:pfam13604 1 TLNAEQAAAVRaLLTSGdrvAVLVGPAGTGKTTAL-KALREAWEAAGYR---VIGLAPTGRAAKVLGEELgipADTIAK 75
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
7-71 |
1.03e-03 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 40.23 E-value: 1.03e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 7 QQHAVEFVTGPCLVL--AGAGSGKTRVItNKIAHLIRQCGYQakhIAAVTFTNKAAREMKERV---AQTL 71
Cdd:cd17933 2 QKAAVRLVLRNRVSVltGGAGTGKTTTL-KALLAALEAEGKR---VVLAAPTGKAAKRLSESTgieASTI 67
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
542-603 |
1.46e-03 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 41.88 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 542 RGESEEELdqVQLMTLHASKGLEFPYVFL--VG---MEEGLLPH--QS-------SIDEDNV---DEER-----RLAYVG 599
Cdd:PRK10876 728 RLESDKHL--VQIVTIHKSKGLEYPLVWLpfITnfrVQDQAFYHdrHSfeavldlNAAEESValaEEERlaedlRLLYVA 805
|
....
gi 1878687111 600 ITRA 603
Cdd:PRK10876 806 LTRS 809
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
207-306 |
2.00e-03 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 41.49 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878687111 207 RLRY--LLVDEYQDTNTSQYELIKLLVGTRAR--FTVVGDDDQSIYSWRGARPQNLVLLQQDFPALdvIKLEQNYRSSGR 282
Cdd:PRK10876 375 RTRYpvAMIDEFQDTDPQQYRIFRRIYRHQPEtaLLLIGDPKQAIYAFRGADIFTYMKARSEVSAH--YTLDTNWRSAPG 452
|
90 100
....*....|....*....|....
gi 1878687111 283 ILKAANILIANNPHVFekrLFSEL 306
Cdd:PRK10876 453 MVNSVNKLFSQTDDPF---LFREI 473
|
|
| |
