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Conserved domains on  [gi|1889613895|ref|WP_182716731|]
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MULTISPECIES: TonB-dependent receptor [Pseudoalteromonas]

Protein Classification

TonB-dependent receptor( domain architecture ID 11446927)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0009279|GO:0055085
PubMed:  36944260|35464957
TCDB:  1.B.14

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
30-657 4.03e-62

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


:

Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 218.54  E-value: 4.03e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  30 VEKISVVGSATNLS----------ITAEEIEQYQASDLADIFRHSPSVSVGGSVGVAQKIYIRGVEDSL--LNITVDGAQ 97
Cdd:COG1629     1 LEEVVVTATRTDESlqdvpgsvsvISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGnrVLVLVDGVP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  98 QTSTLFHHIGRVTIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASYFSNDGTRLSTSVY 177
Cdd:COG1629    81 LNDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGSYGTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 178 GKlSDTWGVLGYFSTVDRENMEDGDGDTIYGtaadqdmMFIKASGELADNHHLSISIEKRDEEGD-------FSARPNWA 250
Cdd:COG1629   155 GG-NGKLAYRLSASYRDSDGYRDNSDSDRYN-------LRAKLGYQLGDDTRLTLSASYSDSDQDspgyltlAALRPRGA 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 251 VQEGDALYP---SEAERETYVANYIFSH-NNLLYLEATAY------------KTESSFNGGRFAWLADIDTYGLDIRNTS 314
Cdd:COG1629   227 MDDGTNPYSndtDDNTRDRYSLSLEYEHlGDGLKLSASAYyryddtdldsdfTPTPADGGTLEQTDFDNRTYGLELRLTY 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 315 ---IIDEHKFVYGVDYRNDEVSS------------GSAAGAKENSEQGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQ 379
Cdd:COG1629   307 dlgFGGKHTLLVGLDYQRQDLDGsgypldlgsgslPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDV 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 380 DilldeYYGTAITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTIDGYLYdgsdiPVADESLVPET 459
Cdd:COG1629   387 D-----DTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPY-----SVGNPDLKPET 456
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 460 VANIEASITYT--NENLSAKASIYNSSLDDVIFEGYEGNS-----VYNNIGTLETKGFEFDLAYRL-NSFDFFIGFSATD 531
Cdd:COG1629   457 STNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDsgfstYYTNAGKARSYGVELELSYQLtPGLSLNASYSYTD 536
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 532 TELDPRDGlysvsyDAIDINGYEFVGLGNSRGNtwvAGVDYDINTDAKVGFSVTKVDSldintlhQAVDLGWTDSLYtln 611
Cdd:COG1629   537 AKFDDDTD------GSADLDGNRLPGVPPLTAN---LGLTYEFPGGWSLGLGVRYVGD-------RYLDDANTQGAP--- 597
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*.
gi 1889613895 612 kPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYIDHSSVGDYSEVF 657
Cdd:COG1629   598 -GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
30-657 4.03e-62

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 218.54  E-value: 4.03e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  30 VEKISVVGSATNLS----------ITAEEIEQYQASDLADIFRHSPSVSVGGSVGVAQKIYIRGVEDSL--LNITVDGAQ 97
Cdd:COG1629     1 LEEVVVTATRTDESlqdvpgsvsvISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGnrVLVLVDGVP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  98 QTSTLFHHIGRVTIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASYFSNDGTRLSTSVY 177
Cdd:COG1629    81 LNDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGSYGTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 178 GKlSDTWGVLGYFSTVDRENMEDGDGDTIYGtaadqdmMFIKASGELADNHHLSISIEKRDEEGD-------FSARPNWA 250
Cdd:COG1629   155 GG-NGKLAYRLSASYRDSDGYRDNSDSDRYN-------LRAKLGYQLGDDTRLTLSASYSDSDQDspgyltlAALRPRGA 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 251 VQEGDALYP---SEAERETYVANYIFSH-NNLLYLEATAY------------KTESSFNGGRFAWLADIDTYGLDIRNTS 314
Cdd:COG1629   227 MDDGTNPYSndtDDNTRDRYSLSLEYEHlGDGLKLSASAYyryddtdldsdfTPTPADGGTLEQTDFDNRTYGLELRLTY 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 315 ---IIDEHKFVYGVDYRNDEVSS------------GSAAGAKENSEQGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQ 379
Cdd:COG1629   307 dlgFGGKHTLLVGLDYQRQDLDGsgypldlgsgslPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDV 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 380 DilldeYYGTAITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTIDGYLYdgsdiPVADESLVPET 459
Cdd:COG1629   387 D-----DTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPY-----SVGNPDLKPET 456
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 460 VANIEASITYT--NENLSAKASIYNSSLDDVIFEGYEGNS-----VYNNIGTLETKGFEFDLAYRL-NSFDFFIGFSATD 531
Cdd:COG1629   457 STNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDsgfstYYTNAGKARSYGVELELSYQLtPGLSLNASYSYTD 536
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 532 TELDPRDGlysvsyDAIDINGYEFVGLGNSRGNtwvAGVDYDINTDAKVGFSVTKVDSldintlhQAVDLGWTDSLYtln 611
Cdd:COG1629   537 AKFDDDTD------GSADLDGNRLPGVPPLTAN---LGLTYEFPGGWSLGLGVRYVGD-------RYLDDANTQGAP--- 597
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*.
gi 1889613895 612 kPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYIDHSSVGDYSEVF 657
Cdd:COG1629   598 -GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
44-678 1.13e-61

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 218.82  E-value: 1.13e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  44 ITAEEIEQYQASDLADIFRHSPS-VSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHH----IGRVTIDPDLLQQ 118
Cdd:TIGR01786  28 ISREQLKSQQVRNLRDLLRYEPGvSVVEGGRGGSQGINIRGLDKNRVAVLVDGIRQNTSYGGQgstfYAINSIDPELIKS 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 119 IDVQAGAGEATSGPGAIGGSIRFKTKDAQDLLNQGEQFGGRVKASYFSNDGTRLSTSVYGKLSDTWGVLGYFSTVDRENM 198
Cdd:TIGR01786 108 IEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSSANNRFTQSVAAAGRNDDVDALVQATYRRGHEL 187
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 199 EDGDGDTIYGTAADQDMM---------FIKASGELADNHHLSISIEKRDEEGD---FSARPNWAVQEGDALYPS---EAE 263
Cdd:TIGR01786 188 KNGNKANIGNESKRSKPNpsdyksqsfLAKLGWQLNDAHRLGLSLEYTQTDYDepeMTNTSYLTKPLGAPLLSStvvLGD 267
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 264 RETYVANYIFSHN---------------NLLYLEATAYKTESSFNG-------GRFAWLADIDTYGLDIRNTSIIDEHK- 320
Cdd:TIGR01786 268 SKTRDRRTGLDYElnpdnswldtvklalDKQYIQLYNYLNATSASDypgvdknGRYKDKYDYYTLGFDTNNKIEFSVHSl 347
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 321 -FVYGVDYRNDEVSSGSAAGAKENSE-------------QGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQDilLDEY 386
Cdd:TIGR01786 348 sLTYGLDRFKDKVSTGDSRRNLPTAAynlygyegenrpvKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPK--ADES 425
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 387 ygtaITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTIDGYLYDGSDIPVADESLVPETVANIEAS 466
Cdd:TIGR01786 426 ----KDYGAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGGPYTFLPNPNLKPETSKNWEIG 501
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 467 ITYTNENLSAKASIYNSSLDDVIFEGYE-----------GNSVYN--NIGTLETKGFEFDLAYRLNSFDFFIGFSATDTE 533
Cdd:TIGR01786 502 INLHFDQLDFKVSYFRNDYKDFIDLGIGvtakgnmaqvgSNTITNyvNIDNARIRGIELSGRYDLGSFFSGPDGWTTTLK 581
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 534 ldprdGLYSVSYDaIDINGYefvgLGNSRGNTWVAGVDYDI-NTDAKVGFSVT-----KVDSLDINTLHQAVDLGWTDSL 607
Cdd:TIGR01786 582 -----YGYTKGKD-SDTNPW----LNAITPLKVVLGLGYDHpDEKWGVGLTLTfsgakDAVDAYATYYENGEAAKAGPLR 651
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1889613895 608 YtlnkPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYIDHSSVGdysEVFGTVVGPYESGRDIRLSISYQF 678
Cdd:TIGR01786 652 T----PSYTVVDLYGYYKPNKNLTLRFGVYNLLDRKYTTWESAR---QAGPLATGYTAPGRNYKASVEYKF 715
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
43-678 1.95e-51

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 188.81  E-value: 1.95e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  43 SITAEEIEQYQASDLADIFRHSP-SVSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHHIGRV-TIDPDLLQQID 120
Cdd:cd01347     4 VITAEDIEKQPATSLADLLRRIPgVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLnTIPPELIERVE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 121 VQAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASY-----FSNDGTRLSTSVYGKLSDTWGVLGYFSTVDR 195
Cdd:cd01347    84 VLKGPSSALYGSGAIGGVVNIITKRPTD------EFGGSVTAGYgsdnsGSSGGGGFDVSGALADDGAFGARLYGAYRDG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 196 ENMEDGDGDTiYGTAADQDMMFIKASGELADNHHLSISIE--KRDEEGDFSARPN-----------WAVQEGDALYPSEA 262
Cdd:cd01347   158 DGTIDGDGQA-DDSDEERYNVAGKLDWRPDDDTRLTLDAGyqDQDADGPGGTLPAngtgsslgggpSSNTNGDRDWDYRD 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 263 eRETYVANYIFSHN----------NLLYLEATAYKTESSFNGGRFAWLA-----------DIDTYGLDIRNTSIID---- 317
Cdd:cd01347   237 -RYRKRASLGLEHDlndtgwtlraNLSYSYTDNDGDPLILNGGNNAAGGdlgrsgysserDTTQLGFDAGLNAPFGtgpv 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 318 EHKFVYGVDYRNDEVSSgsaagakenseqgSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQdilldeyYGTAITESASS 397
Cdd:cd01347   316 AHTLTLGVEYRREELDE-------------KQTALYAQDTIELTDDLTLTLGLRYDHYDQDS-------KDTIAGGTTAK 375
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 398 LDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFtidGYLYDGSDIPVADESLVPETVANIEASITYTNEN-LSA 476
Cdd:cd01347   376 KSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY---GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDgLTL 452
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 477 KASIYNSSLDDVIFEGYEGN-----SVYNNIGTLETKGFEFDLAYRLN-SFDFFIGFSATDTELDPRDGlysvsydaiDI 550
Cdd:cd01347   453 SAALFRIDIKNEIVSTPTNTglglvTVYVNGGKARIRGVELEASYDLTdGLGLTGSYTYTDTEVKRTDG---------AT 523
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 551 NGYEFVGLGNSRGNtwvAGVDYDINTDA-KVGFSVTKVDSldintlHQAVDLGWTDSLYTlnkPSYTTVDLYGQWNVTNA 629
Cdd:cd01347   524 TGNRLPGIPKHTAN---LGLDYELPDEGlTAGGGVRYRGK------QYADTANGNNTVKV---PGYTLVDLSASYQFTKN 591
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*....
gi 1889613895 630 LLFNVAVTNLFNELYIDHSSVGDYSevfgtVVGPYESGRDIRLSISYQF 678
Cdd:cd01347   592 LTLRLGVNNLFDKDYYTSLSVRGSG-----LYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
305-677 2.48e-28

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 119.10  E-value: 2.48e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 305 TYGLDIRNTSIIDEHKFVYGVDYRNDEVSSGSAAGA------KENSEQGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFK 378
Cdd:pfam00593 124 ELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPanpsssSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTD 203
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 379 QDilldeyyGTAITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTiDGYLYDGSDIPVADESLVPE 458
Cdd:pfam00593 204 GD-------DGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYG-SGSGGGGGAVAGGNPDLKPE 275
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 459 TVANIEASITYTNENLSAKASIYNSSLDDVIFEGYEGN------SVYNNIGTLETKGFEFDLAYRLNSFDFFIG-FSATD 531
Cdd:pfam00593 276 TSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPglggtvYTYTNVGKARIRGVELELSGRLWGLGLSGGgYTYTD 355
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 532 TELDprdglysvsyDAIDINGYEfvgLGNSRGNTWVAGVDYDINTDA-KVGFSVTKVDSldintlhqaVDLGWTDSLYTL 610
Cdd:pfam00593 356 ADDD----------ADADDTGNP---LPNVPRHTANLGLTYDFPLGGwGARLGARYVGS---------GERRYGDAANTF 413
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1889613895 611 NKPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYidhssVGDYSEVFGTVVGPYESGRDIRLSISYQ 677
Cdd:pfam00593 414 KTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYY-----KRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
PRK13486 PRK13486
TonB-dependent receptor;
1-678 1.79e-12

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 70.44  E-value: 1.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   1 MKKLALMSAICASFSSP--IYAQELAKNTASVEKISVVGSATNLS-ITAEEIEQYQASDLADIFR--HSPSVSVGGSVGV 75
Cdd:PRK13486    3 ITTLASVVIPCLGFSASsiAAAEDVMIVSASGYEKKLTNAAASVSvISQEELQSSQYHDLAEALRsvEGVDVESGTGKTG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  76 AQKIYIRGVEDSLLNITVDGAQQ------TSTLFHHIGRVTIDP-DLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQD 148
Cdd:PRK13486   83 GLEISIRGMPASYTLILIDGVRQggssdvTPNGFSAMNTGFMPPlAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNAD 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 149 llnqgeqfggrvKASYFSNDGTRLSTSvygklsDTWGVLGYFSTVDRENMEDGDGD-TIYGTAADQDMMFIKAsgeLADN 227
Cdd:PRK13486  163 ------------KWLSSVNAGLNLQES------NKWGNSSQFNFWSSGPLVDDSVSlQVRGSTQQRQGSSVTS---LSDT 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 228 HHLSISIEKRDEEGDFSARPNWAVQEGDALYPS-EAERETY------VANYIFSHNNLLYLE----ATAYKTESSF---- 292
Cdd:PRK13486  222 AATRIPYPTESQNYNLGARLDWKASEQDVLWFDmDTTRQRYdnrdgqLGSLTGGYDRTLRYErnkiSAGYDHTFTFgtwk 301
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 293 ---------NGGR----------FAWLADIDTyglDIRNTSII----------DEHKFVYGVDYRNDEVSSGSA-AGAKE 342
Cdd:PRK13486  302 sylnwneteNKGRelvrsvlkrdKWGLAGQPR---ELKESNLIlnsllltplgESHLVTVGGEFQSSSMKDGVVlASTGE 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 343 NSEQGSvLGVYAQGYSDITPQLLLSYGVRFDSYkfkqdilldEYYGTAITESASslddnelsfnigLAYDINDAWT---- 418
Cdd:PRK13486  379 TFRQKS-WSVFAEDEWHLTDALALTAGSRYEHH---------EQFGGHFSPRAY------------LVWDVADAWTlkgg 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 419 VGLGYAEAARGkQIGDGftIDGYLYDGSDIPVADESLVPETVANIEASITYTNEN-LSAKAS---------IYNSSLDDv 488
Cdd:PRK13486  437 VTTGYKAPRMG-QLHKG--ISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAgLNANVTgfmtdfsnkIVSYSIND- 512
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 489 ifegyeGNSVYNNIGTLETKGFEFDLAYRLNSFDFFIGFSATDTELDPRDglysvsydaidingyefvglGNSRGNTWVA 568
Cdd:PRK13486  513 ------NTNSYVNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRD--------------------GDNKGAPLSY 566
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 569 GVDYDINtdAKVGFSVTKvdslDINTLHQAVDLGWT-------DSLYTLNKPSY----------TTVDLYGQWNVTNALL 631
Cdd:PRK13486  567 TPEHMVN--AKLNWQITE----EVASWLGARYRGKTprftqnySSLSAVQKKVYdekgeylkawTVVDAGLSWKMTDALT 640
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1889613895 632 FNVAVTNLFNELYIDHS---------SVGDYSEVFGTVVGPYESGRDIRLSISYQF 678
Cdd:PRK13486  641 LNAAVNNLLNKDYSDVSlysagkstlYAGDYFQTGSSTTGYVIPERNYWMSLNYQF 696
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
30-657 4.03e-62

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 218.54  E-value: 4.03e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  30 VEKISVVGSATNLS----------ITAEEIEQYQASDLADIFRHSPSVSVGGSVGVAQKIYIRGVEDSL--LNITVDGAQ 97
Cdd:COG1629     1 LEEVVVTATRTDESlqdvpgsvsvISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGnrVLVLVDGVP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  98 QTSTLFHHIGRVTIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASYFSNDGTRLSTSVY 177
Cdd:COG1629    81 LNDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGSYGTYRASLSLS 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 178 GKlSDTWGVLGYFSTVDRENMEDGDGDTIYGtaadqdmMFIKASGELADNHHLSISIEKRDEEGD-------FSARPNWA 250
Cdd:COG1629   155 GG-NGKLAYRLSASYRDSDGYRDNSDSDRYN-------LRAKLGYQLGDDTRLTLSASYSDSDQDspgyltlAALRPRGA 226
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 251 VQEGDALYP---SEAERETYVANYIFSH-NNLLYLEATAY------------KTESSFNGGRFAWLADIDTYGLDIRNTS 314
Cdd:COG1629   227 MDDGTNPYSndtDDNTRDRYSLSLEYEHlGDGLKLSASAYyryddtdldsdfTPTPADGGTLEQTDFDNRTYGLELRLTY 306
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 315 ---IIDEHKFVYGVDYRNDEVSS------------GSAAGAKENSEQGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQ 379
Cdd:COG1629   307 dlgFGGKHTLLVGLDYQRQDLDGsgypldlgsgslPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDV 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 380 DilldeYYGTAITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTIDGYLYdgsdiPVADESLVPET 459
Cdd:COG1629   387 D-----DTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPY-----SVGNPDLKPET 456
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 460 VANIEASITYT--NENLSAKASIYNSSLDDVIFEGYEGNS-----VYNNIGTLETKGFEFDLAYRL-NSFDFFIGFSATD 531
Cdd:COG1629   457 STNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDsgfstYYTNAGKARSYGVELELSYQLtPGLSLNASYSYTD 536
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 532 TELDPRDGlysvsyDAIDINGYEFVGLGNSRGNtwvAGVDYDINTDAKVGFSVTKVDSldintlhQAVDLGWTDSLYtln 611
Cdd:COG1629   537 AKFDDDTD------GSADLDGNRLPGVPPLTAN---LGLTYEFPGGWSLGLGVRYVGD-------RYLDDANTQGAP--- 597
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*.
gi 1889613895 612 kPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYIDHSSVGDYSEVF 657
Cdd:COG1629   598 -GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
44-678 1.13e-61

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 218.82  E-value: 1.13e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  44 ITAEEIEQYQASDLADIFRHSPS-VSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHH----IGRVTIDPDLLQQ 118
Cdd:TIGR01786  28 ISREQLKSQQVRNLRDLLRYEPGvSVVEGGRGGSQGINIRGLDKNRVAVLVDGIRQNTSYGGQgstfYAINSIDPELIKS 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 119 IDVQAGAGEATSGPGAIGGSIRFKTKDAQDLLNQGEQFGGRVKASYFSNDGTRLSTSVYGKLSDTWGVLGYFSTVDRENM 198
Cdd:TIGR01786 108 IEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSSANNRFTQSVAAAGRNDDVDALVQATYRRGHEL 187
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 199 EDGDGDTIYGTAADQDMM---------FIKASGELADNHHLSISIEKRDEEGD---FSARPNWAVQEGDALYPS---EAE 263
Cdd:TIGR01786 188 KNGNKANIGNESKRSKPNpsdyksqsfLAKLGWQLNDAHRLGLSLEYTQTDYDepeMTNTSYLTKPLGAPLLSStvvLGD 267
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 264 RETYVANYIFSHN---------------NLLYLEATAYKTESSFNG-------GRFAWLADIDTYGLDIRNTSIIDEHK- 320
Cdd:TIGR01786 268 SKTRDRRTGLDYElnpdnswldtvklalDKQYIQLYNYLNATSASDypgvdknGRYKDKYDYYTLGFDTNNKIEFSVHSl 347
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 321 -FVYGVDYRNDEVSSGSAAGAKENSE-------------QGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQDilLDEY 386
Cdd:TIGR01786 348 sLTYGLDRFKDKVSTGDSRRNLPTAAynlygyegenrpvKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPK--ADES 425
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 387 ygtaITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTIDGYLYDGSDIPVADESLVPETVANIEAS 466
Cdd:TIGR01786 426 ----KDYGAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGGPYTFLPNPNLKPETSKNWEIG 501
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 467 ITYTNENLSAKASIYNSSLDDVIFEGYE-----------GNSVYN--NIGTLETKGFEFDLAYRLNSFDFFIGFSATDTE 533
Cdd:TIGR01786 502 INLHFDQLDFKVSYFRNDYKDFIDLGIGvtakgnmaqvgSNTITNyvNIDNARIRGIELSGRYDLGSFFSGPDGWTTTLK 581
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 534 ldprdGLYSVSYDaIDINGYefvgLGNSRGNTWVAGVDYDI-NTDAKVGFSVT-----KVDSLDINTLHQAVDLGWTDSL 607
Cdd:TIGR01786 582 -----YGYTKGKD-SDTNPW----LNAITPLKVVLGLGYDHpDEKWGVGLTLTfsgakDAVDAYATYYENGEAAKAGPLR 651
                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1889613895 608 YtlnkPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYIDHSSVGdysEVFGTVVGPYESGRDIRLSISYQF 678
Cdd:TIGR01786 652 T----PSYTVVDLYGYYKPNKNLTLRFGVYNLLDRKYTTWESAR---QAGPLATGYTAPGRNYKASVEYKF 715
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
4-630 6.65e-61

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 214.72  E-value: 6.65e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   4 LALMSAICASFSSPIYAQELAKNTASVEKISVVGSATNLS----------ITAEEIEQYQASDLADIFRHSP--SVSVGG 71
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSlsdapasvsvITAEEIEKLGATDLADALRLLPgvSVTRSG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  72 SVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHHIGRV-TIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDll 150
Cdd:COG4771    81 GRGGSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDLsYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTD-- 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 151 nqgeQFGGRVKASYFSNDGTRLSTSV-YGKLSDTWGVLGYFSTVDRENMEDGDGDTIYG-TAADQDMMFIKASGELADNH 228
Cdd:COG4771   159 ----ELEGSVSLGYGSNGNGTYSGSLsLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGnSGYERYNLNAKLGYRLSDNH 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 229 HLSISIEKRDEE---GDFSARPNWAVQEGDALYPSEAERETYVANYIFSHNNllYLEATAYKTESSFNGGRFAWLA---- 301
Cdd:COG4771   235 RLSLSGGYSRQDrdgGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNGDLGD--NLDLSLYYSRTDRDSTNGSLGGstgs 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 302 ----DIDTYGLDIRNTSIIDE-HKFVYGVDYRNDEVSSGSAAGAKENSEQgsVLGVYAQGYSDITPQLLLSYGVRFDSYk 376
Cdd:COG4771   313 fsdsDDTTYGLELDLTYPLGGnHTLTLGAEYRYDDLDSSSFLGGADASRD--TYGLFAQDEWKLTDKLTLTAGLRYDYY- 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 377 fkqdilldEYYGTAitesasslDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTidGYLYDGSDIPVADESLV 456
Cdd:COG4771   390 --------STFGAS--------NYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYG--SGTGTPGRYVLGNPDLK 451
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 457 PETVANIEASITY--TNENLSAKASIYNSSLDDVIFEGYEGN-----SVYNNIGTLETKGFEFDLAYRLNS-FDFFIGFS 528
Cdd:COG4771   452 PETSDNYELGLEYrlGNGGLSLSLTGFYTDIKDLIVLVPVGPgpgdvLQYENVGKARTYGLELELKYRLGKgLTLTASYT 531
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 529 ATDTELDprdglysvsydaidiNGYEFVGLGNSRGNTWVAGVDYDINTDAKVGFSVTKVDSLDINTlhqavdlgwTDSLY 608
Cdd:COG4771   532 YLDSKID---------------DGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTP---------PSGRL 587
                         650       660
                  ....*....|....*....|..
gi 1889613895 609 TLNKPSYTTVDLYGQWNVTNAL 630
Cdd:COG4771   588 EGYTPGYTLLDLRASYKLTKNL 609
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
20-678 9.19e-61

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 215.33  E-value: 9.19e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  20 AQELAKNTASVEKISvvgsatnlsitAEEIEQYQASDLADIFRHSPS-VSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQ 98
Cdd:TIGR01785  12 RQVLSEAPASVSVIS-----------GEQIESKQANNLADALNTVPGvDVTGGGRPPGQSINIRGLQDNRVLVVVDGARQ 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  99 -TSTLFHHIGRVTIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDLLNQGEQFGGRVKASYFS-NDGTRLSTSV 176
Cdd:TIGR01785  81 nYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLAKLSYGSnNNSFGGSVAV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 177 YGKLSDTWGVLGYFSTVDRENMEDGDGDTIYGTAADQDMMFIKASGELADNHHLSISI----EKRDEEGDFSARPNWAVQ 252
Cdd:TIGR01785 161 AGRLDDNLDALVAATYRDGGNYRNGNKEEATNSAYVQKNLLAKLGWQLDDAQRLEFSYftteGSLDEAQNSGPGTEYVLG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 253 EGDALYPSEAERETYVANYIFS--HNNLLYLEATAYKTESSFN-------GGRFAWlADIDTYGLDIRNTS---IIDEHK 320
Cdd:TIGR01785 241 SSSTLLASSTRDRSATLTYNWTpeDNPWLDATASLYYNRTENDndrsargVGREEG-YQYTTYGATLQNTSrfdVASWST 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 321 FVYGVDYRNDEVSSGSAAGAKENSE-------QGSVLGVYAQG-YSDITPQLLLSYGVRFDSYKFKQDilldeyygTAIT 392
Cdd:TIGR01785 320 LTYGVDWMKDKRRTESFDPNSVTTIvpnppsaKEYFFGLFLQDnIPLLDDRLTLSAGLRYDHYKLSPK--------TTAD 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 393 ESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGF-TIDGYLYDGSDIPVADESLVPETVANIEASITYTN 471
Cdd:TIGR01785 392 TEAVDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYgTGDHPGTPGGYTFAPNPNLKPETSKTWELGANLSF 471
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 472 EN-------LSAKASIYNSSLDDVIFEGYEG----------NSVYNNIGTLETKGFEFDLAYRLNsfDFFIGFSATDTel 534
Cdd:TIGR01785 472 DNllldndqLQFKVAYFYNDVKDFIDLTIGVtdnvtagmnnITQYVNIDGARIRGIEASASYDAG--LWATGLSYGYT-- 547
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 535 dprdglysvsyDAIDINGYEfvGLGNSRGNTWVAGVDYDI-NTDAKVGFSVTKVDSLDINTlhQAVDLGwtdSLYTLNKP 613
Cdd:TIGR01785 548 -----------IGKDQNTNQ--WLSNIPPLKLVVTVGYRFpDRRLDLGAKAAYYERQSESP--TTEDVA---ANGLLTTP 609
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1889613895 614 SYTTVDLYGQWNVT--NALLFNVAVTNLFNELYIDHSSVgdysevfgTVVGPyesGRDIRLSISYQF 678
Cdd:TIGR01785 610 GYTVVDLYATYQPNavKGLTVRFGVNNLTDRKYTPAQSV--------PGAGP---GRNFKGSVKYQF 665
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
43-678 1.95e-51

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 188.81  E-value: 1.95e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  43 SITAEEIEQYQASDLADIFRHSP-SVSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHHIGRV-TIDPDLLQQID 120
Cdd:cd01347     4 VITAEDIEKQPATSLADLLRRIPgVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLnTIPPELIERVE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 121 VQAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASY-----FSNDGTRLSTSVYGKLSDTWGVLGYFSTVDR 195
Cdd:cd01347    84 VLKGPSSALYGSGAIGGVVNIITKRPTD------EFGGSVTAGYgsdnsGSSGGGGFDVSGALADDGAFGARLYGAYRDG 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 196 ENMEDGDGDTiYGTAADQDMMFIKASGELADNHHLSISIE--KRDEEGDFSARPN-----------WAVQEGDALYPSEA 262
Cdd:cd01347   158 DGTIDGDGQA-DDSDEERYNVAGKLDWRPDDDTRLTLDAGyqDQDADGPGGTLPAngtgsslgggpSSNTNGDRDWDYRD 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 263 eRETYVANYIFSHN----------NLLYLEATAYKTESSFNGGRFAWLA-----------DIDTYGLDIRNTSIID---- 317
Cdd:cd01347   237 -RYRKRASLGLEHDlndtgwtlraNLSYSYTDNDGDPLILNGGNNAAGGdlgrsgysserDTTQLGFDAGLNAPFGtgpv 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 318 EHKFVYGVDYRNDEVSSgsaagakenseqgSVLGVYAQGYSDITPQLLLSYGVRFDSYKFKQdilldeyYGTAITESASS 397
Cdd:cd01347   316 AHTLTLGVEYRREELDE-------------KQTALYAQDTIELTDDLTLTLGLRYDHYDQDS-------KDTIAGGTTAK 375
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 398 LDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFtidGYLYDGSDIPVADESLVPETVANIEASITYTNEN-LSA 476
Cdd:cd01347   376 KSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY---GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDgLTL 452
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 477 KASIYNSSLDDVIFEGYEGN-----SVYNNIGTLETKGFEFDLAYRLN-SFDFFIGFSATDTELDPRDGlysvsydaiDI 550
Cdd:cd01347   453 SAALFRIDIKNEIVSTPTNTglglvTVYVNGGKARIRGVELEASYDLTdGLGLTGSYTYTDTEVKRTDG---------AT 523
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 551 NGYEFVGLGNSRGNtwvAGVDYDINTDA-KVGFSVTKVDSldintlHQAVDLGWTDSLYTlnkPSYTTVDLYGQWNVTNA 629
Cdd:cd01347   524 TGNRLPGIPKHTAN---LGLDYELPDEGlTAGGGVRYRGK------QYADTANGNNTVKV---PGYTLVDLSASYQFTKN 591
                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*....
gi 1889613895 630 LLFNVAVTNLFNELYIDHSSVGDYSevfgtVVGPYESGRDIRLSISYQF 678
Cdd:cd01347   592 LTLRLGVNNLFDKDYYTSLSVRGSG-----LYGYYGPGRTYYLSVSYKF 635
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
44-678 2.22e-42

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 162.97  E-value: 2.22e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  44 ITAEEIEQYQASDLADIFRHSPSVSVGGSVGVAQK--IYIRGV--EDSLLNITVDGAQQTSTlfhhIGRVTIDPDLLQQI 119
Cdd:TIGR01783   9 ITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFgnITIRGFglEVDIDNVYLDGVPLLSR----GNLAIVDPAMVERV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 120 DVQAGAGEATSGPGAIGGSIRFKTKDAQDLLNQGEQFGgrvkASYFSNDGTRLSTSVYGKLSDTWGVLGYFSTVDRENME 199
Cdd:TIGR01783  85 EVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFG----AGTRSGYRTAFDLGGPLGADGTFRGRLNGARQDGDSFY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 200 DGDGDTIYgtaadqdmmFIKASGELADNHHLSISIEKRDeEGDFSARPNWAVQEGDALYPSEAERETYV----------- 268
Cdd:TIGR01783 161 DGAGEETR---------LGATATDWQLDDRTLLRLGAYY-QKERDRGGYGGLPASGGTSGRDLSSDRYLgtssnrnyddr 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 269 --------ANYIFSHNNLLYLEATAYKTES-SFNGGRFAWLADIDTYGL-------DIRNTSIID-----------EHKF 321
Cdd:TIGR01783 231 eylsyglsLEYQFNDVWTGKQNLRYSYFDTdSNQVQASGYSSDGGLFGRsltvvnvKQDRVQIDAgldgefetgpiEHDL 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 322 VYGVDYRN---------DEVSSGSAAGAKENSEQGSVlGVYAQGYSDITPQ----------------LLLSYGVRFDSYK 376
Cdd:TIGR01783 311 LLGVSYGQrttnrfnntGYPSDNIYSLTATSSARTDI-GDSPKDRALSSTTkalngvalqrilladkWTLTLGGRYDSVD 389
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 377 FKQDIlldeyygtAITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTIdgylydgsdipVADESLV 456
Cdd:TIGR01783 390 VKSNN--------GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAG-----------NSGDILE 450
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 457 PETVANIEASITYTNEN-LSAKASIYNSSLDDVIFEGYEGNSVYNNIGTLETKGFEFDLAYRL-NSFDFFIGFSATDTEL 534
Cdd:TIGR01783 451 PEKGKNYELGVRYDLGDsLLATAALFRITKDNQLVQDPVNGTFSVNAGKTRNRGVELEARGYLtPGLSLSAGYTYTDAEF 530
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 535 dprdglysvsYDAIDIN--GYEFVGLGNSRGNTWVAGVDYDINTDAKVGFSVTKVDSLDIntlhqavdlgwtDSLYTLNK 612
Cdd:TIGR01783 531 ----------TEDTNGDtqGNTVPFVPKHTASLWASYAPPVGDNGLTLGGGVQYTGKAYV------------DGGNTGKV 588
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1889613895 613 PSYTTVDLYGQWNVTNALLFNVA--VTNLFNELYIDHSSvgDYSEVFGTVVGPyesGRDIRLSISYQF 678
Cdd:TIGR01783 589 PSYTVVDLSVRYDLTKKKNLTLAlnVNNLFDRDYYTSGY--RWGPSAYIYPGA---PRTVGLSVSYDF 651
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
43-678 3.23e-39

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 153.49  E-value: 3.23e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  43 SITAEEIEQYQASDLADIFRHSP-SVSVGGSVGVAQKIYIRGVEDSLlNITVDGAQQTstlfhhiGRVTIDPDLLQQIDV 121
Cdd:COG4774    15 VVTRELIEDQGATSLADALRNVPgVTFGAGEGGNGDSFSIRGFSASG-DIYVDGLRDP-------GQYRRDTFNLERVEV 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 122 QAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASYFSNDGTRLSTSVYGKLSDTWGVlgyfstvdRENMEDG 201
Cdd:COG4774    87 LKGPASVLYGRGSPGGVINLVTKRPTD------EPFTEVTLTYGSDGQRRATLDVNGPLGDDLAY--------RLNGMYR 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 202 DGDT-IYGTAADQDMMFIKASGELADNHHLSISIEKRDEEGdfsaRPNWAVQEGDALYPSEAERETY------------- 267
Cdd:COG4774   153 DSDSyRDGVDNDRWGIAPSLTWRLGDRTRLTLDYEYQDDDR----TPDYGVPAVANGRPVDVDRSTFygqpddysdsetd 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 268 VANYIFSH---------NNLLYLEATAYKTESSFNGGRFAWLADIDTYGLDIRNTSIID-------------EHKFVYGV 325
Cdd:COG4774   229 SATLRLEHdfndnwtlrNALRYSDYDRDYRNTYPTGGNATGTVTRSAYRRDQDNDTLSNqtdltgkfdtggvKHTLLAGV 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 326 DYRNDEVSS------------------------GSAAGAKENSEQGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFkqdi 381
Cdd:COG4774   309 EYSREDSDNarysgggtaptvnlynpvygapvtGPTLGGADNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDT---- 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 382 lldEYYGTAITESASSLDDNELSFNIGLAYDINDAWTVglgYAEAARGKQIGDGFtidgylydgSDIPVADESLVPETVA 461
Cdd:COG4774   385 ---DYTDRTTGATTSSYDDSAFSPRAGLVYKPTPNLSL---YASYSTSFNPGGGA---------PSLSNAGQALDPEKSR 449
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 462 NIEASITYT--NENLSAKASIYNSSLDDVIFEGYEGNSVYNNIGTLETKGFEFDLAYRLN-SFDFFIGFSATDTELDprd 538
Cdd:COG4774   450 QYEVGVKWDllDGRLSLTAALFRIEKTNVRTTDPANPGVYVQTGEQRSRGVELEATGELTpGWSVLAGYTYLDAEIT--- 526
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 539 glysvSYDAIDINGYEFVGLGNSRGNTWVagvDYDINTDA-KVGFSVTKVDSLdintlhqavdlgWTDSLYTLNKPSYTT 617
Cdd:COG4774   527 -----KSANAANVGNRLPNVPRHSASLWT---TYDLPLPGlTLGGGVRYVGSR------------YADAANTVKLPSYTR 586
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1889613895 618 VDLYGQWNVTNALLFNVAVTNLFNELYIDHSSVGDYSevfgtVVGPyesGRDIRLSISYQF 678
Cdd:COG4774   587 FDAGASYRLNKNLTLRLNVNNLTDKRYYASAYGSGYV-----TPGA---PRTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
43-678 1.57e-38

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 151.97  E-value: 1.57e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  43 SITAEEIEQYQASDLADIFRHSP-SVSVGGSVGVAQKIYIRGVEDSllNITVDGAQQTSTlfhhiGRVTIDPDLLQQIDV 121
Cdd:COG4773    71 VVTRQLIEDQGATTLDDALRNVPgVTVSSYDGGGRDSFSIRGFSID--NYLRDGLPLGGF-----GGGQPDTANLERVEV 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 122 QAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASYFSNDGTRLSTSVYGKLSDTWGVLGYFSTVDREN---M 198
Cdd:COG4773   144 LKGPAGLLYGAGSPGGLVNLVTKRPTA------EPQGEVSLSAGSWDTYRATADVGGPLNEDGTLRYRLNAAYEDGdsfR 217
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 199 EDGDGDTIYGTAAdqdmmfikASGELADNHHLSISIE--KRDEEGDFSARPnwaVQEGDALYPSEA---------ERETY 267
Cdd:COG4773   218 DGVDNRRTLIAPS--------LDWDLTDDTTLTLGAEyqDDDSTGDRGFLP---LDGTLLDLPRSTnlgepwdyyDTETT 286
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 268 VANYIFSH--------------------NNLLYLEATAYKTESSFNGGRFAWLADIDTYGLDIRNTSIID----EHKFVY 323
Cdd:COG4773   287 TLFAELEHrfnddwslranarysdsdrdGRSAYAYGAPDAATGTLTRYASARDGDSRSDSLDANLNGKFEtgglEHTLLV 366
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 324 GVDYRNDEVSSGSAA----------------------GAKENSEQgsvLGVYAQGYSDITPQLLLSYGVRFDSYKFKQDi 381
Cdd:COG4773   367 GADYSRYDSDSDSATagtiniynpvygnlpepdfdasDTDTTTRQ---TGLYAQDQISLTDRLSLLLGGRYDWYETDST- 442
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 382 lldeyygTAITESASSLDDNELSFNIGLAYDINDAWTVglgYAEAARGKQIGDGFTIDGylydgsdipvadESLVPETVA 461
Cdd:COG4773   443 -------NRLGGSTTSYDDSAFTPRAGLVYDLTPGLSL---YASYSESFEPQSGADNNG------------NPLDPETGK 500
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 462 NIEASI--TYTNENLSAKASIYNSSLDDVIFEGYEGNSVYNNIGTLETKGFEFDLAYRL-NSFDFFIGFSATDTEldprd 538
Cdd:COG4773   501 QYEAGVkgELFDGRLNATLAVFDITQKNVATTDPDNPNFYVQVGEVRSRGVELELSGELtPGLNLIAGYTYTDAK----- 575
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 539 glysVSYDAIDINGYEFVGLGNSRGNTWVagvDYDINTDA----KVGFSVTKVDSLdintlhqavdlgWTDSLYTLNKPS 614
Cdd:COG4773   576 ----ITKDADALEGKRLTNVPRHTASLWT---TYRFPSGAlkglGLGGGVRYVGER------------YGDAANTFTLPS 636
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1889613895 615 YTTVDLYGQWNVTNALLFNVAVTNLFNELYIdhSSVGDYSEVFgtvvgpYESGRDIRLSISYQF 678
Cdd:COG4773   637 YTLVDAGARYDLGKNWTLQLNVNNLFDKKYY--ASSGSRGYVY------YGAPRNVRLSLSYKF 692
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
305-677 2.48e-28

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 119.10  E-value: 2.48e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 305 TYGLDIRNTSIIDEHKFVYGVDYRNDEVSSGSAAGA------KENSEQGSVLGVYAQGYSDITPQLLLSYGVRFDSYKFK 378
Cdd:pfam00593 124 ELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPanpsssSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTD 203
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 379 QDilldeyyGTAITESASSLDDNELSFNIGLAYDINDAWTVGLGYAEAARGKQIGDGFTiDGYLYDGSDIPVADESLVPE 458
Cdd:pfam00593 204 GD-------DGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYG-SGSGGGGGAVAGGNPDLKPE 275
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 459 TVANIEASITYTNENLSAKASIYNSSLDDVIFEGYEGN------SVYNNIGTLETKGFEFDLAYRLNSFDFFIG-FSATD 531
Cdd:pfam00593 276 TSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPglggtvYTYTNVGKARIRGVELELSGRLWGLGLSGGgYTYTD 355
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 532 TELDprdglysvsyDAIDINGYEfvgLGNSRGNTWVAGVDYDINTDA-KVGFSVTKVDSldintlhqaVDLGWTDSLYTL 610
Cdd:pfam00593 356 ADDD----------ADADDTGNP---LPNVPRHTANLGLTYDFPLGGwGARLGARYVGS---------GERRYGDAANTF 413
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1889613895 611 NKPSYTTVDLYGQWNVTNALLFNVAVTNLFNELYidhssVGDYSEVFGTVVGPYESGRDIRLSISYQ 677
Cdd:pfam00593 414 KTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYY-----KRYYSSGGGNLGGYPGPGRTFYLGLSYK 475
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
7-678 2.88e-27

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 117.34  E-value: 2.88e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   7 MSAICASFSSPIYAQELAKNTAsVEKISVVGSATNLS-----------ITAEEIEQYQASDLADIFRHSPSVSVGGSVGV 75
Cdd:COG4772     1 MRRALAAALLLAAAAAAEAATT-LETVVVTGSRAAEArlkdvpgsvsvVDREELENQAATSLREVLRRVPGVNVQEEDGF 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  76 AQ--KIYIRGV-----------EDSLLnITVDGAQQTSTLFHHigrvtiDPDLLQQIDVQAGAGEATSGPGAIGGSIRFK 142
Cdd:COG4772    80 GLrpNIGIRGLgprrsrgitllEDGIP-IAPAPYGDPAAYYFP------DLERMERIEVLRGAAALRYGPQTVGGAINFV 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 143 TKDAQdllnqgEQFGGRVKASYFSNDGTRLSTSVygklSDTWGVLGYFSTVDRENmedGDGDTiYGTAADQDMMFIKASG 222
Cdd:COG4772   153 TRTIP------TAFGGELRVTGGSFGYRRTHASV----GGTVGNFGYLVEYSRKR---GDGFR-DNSGFDINDFNAKLGY 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 223 ELADNHHLSISIEKRDEEG---------DFSARPNWAVQEGDALypsEAERETYVANYIFSHNNLLYLEATAYKTESSFN 293
Cdd:COG4772   219 RLSDRQELTLKFQYYDEDAntpggltdaQFDADPRQSYRPADQF---DTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRN 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 294 GGRFAWLADID--------------TYGLDIRNTSIID----EHKFVYGVDYRNDEVSSGSAAGAKENSEQGSVLG---- 351
Cdd:COG4772   296 WYIRQNTADPNtpglglrgnprgyrSYGIEPRLTHRFElggvPHTLEVGLRYHREEEDRKQYVNTYGQGRSGAGLRrdrr 375
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 352 -------VYAQGYSDITPQLLLSYGVRFDSYKFKQDILLDEYYGTAITESASSlddNELSFNIGLAYDINDAWTVglgYA 424
Cdd:COG4772   376 fsadalaAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRYSTRTGGDDSGSNSY---SEFLPGLGLLYQLTDNLQL---YA 449
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 425 EAARG---KQIGDGFTIDGylydgsdipvADESLVPETVANIEASITYT-NENLSAKASIYNSSLDDVIFEGYEGN---S 497
Cdd:COG4772   450 NVSRGfepPTFGDLAYGNG----------GNPDLKPEKSWNYELGTRGRiGNGLSAEVALFYIDYDNELGSCSAAGgdrS 519
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 498 VYNNIGTLETKGFEFDLAYRL-----NSFDFFIGFSATDTELDprdglysvSYDAIDINGYEFVGLgnSRgNTWVAGVDY 572
Cdd:COG4772   520 TFTNAGETRHQGLELALDYDLlkgggLGLPLFAAYTYTDAEFT--------SDFGPVFAGNRLPYV--PR-HQLTAGLGY 588
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 573 DiNTDAKVGFSVTKVDSldintlhQAVDLGWTDSLYTLNK-PSYTTVDLYGQWNVTNALLFNVAVTNLFNELYIdhSSVG 651
Cdd:COG4772   589 E-HGGWTANLNGRYVSE-------QFTDAANTVADGSFGKiPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYI--ASRA 658
                         730       740
                  ....*....|....*....|....*..
gi 1889613895 652 DYSEvFGTVVGPyesGRDIRLSISYQF 678
Cdd:COG4772   659 PNYA-AGIRPGP---PRTVYAGLRLKF 681
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
31-299 4.58e-18

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 84.92  E-value: 4.58e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  31 EKISVVGSATNlSITAEEIEQYQASDLADIFRHSP--SVSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHHIGR 108
Cdd:COG4206    10 QSKSDLTGSVT-VIDAEELERSGATSLADALRRVPgvQVSSSGGPGSAASISIRGLGSNQTLVLIDGVPLNDPSLGGVDL 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 109 VTIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDllnqgeQFGGRVKASYFSNDGTRLSTSVYGKlSDTWGVLG 188
Cdd:COG4206    89 SLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKK------GFKGSVSASYGSFGTRRLSASLSGG-AGKFSYSL 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 189 YFSTVDRENMEDGDGDTIYGTAADQDMMFIKASGELADNHHLSISIEKRDEEGDFSARPNWAVQEGDAL----YPSEAER 264
Cdd:COG4206   162 SASYRRSDGYRYNDPDLRNNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSERGYPGAVGSDRNLRLSLsleyKLSDGWS 241
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1889613895 265 ETYVANYIFSHNNLLYLEATAYKTESSFNGGRFAW 299
Cdd:COG4206   242 LLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
31-137 1.99e-15

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 72.30  E-value: 1.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  31 EKISVVGSATnlSITAEEIEQYQASDLADIFRHSP-SVSVGGSVGVAQKIYIRGVEDSLLNITVDGAQQTSTLFHHIGRV 109
Cdd:pfam07715   1 DLRDTPGSVS--VVTAEDIEDQGATNLADALRGVPgVSVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGGGGSVDLN 78
                          90       100
                  ....*....|....*....|....*...
gi 1889613895 110 TIDPDLLQQIDVQAGAGEATSGPGAIGG 137
Cdd:pfam07715  79 SIDPEDIERVEVLKGPASALYGSGAIGG 106
PRK13486 PRK13486
TonB-dependent receptor;
1-678 1.79e-12

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 70.44  E-value: 1.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   1 MKKLALMSAICASFSSP--IYAQELAKNTASVEKISVVGSATNLS-ITAEEIEQYQASDLADIFR--HSPSVSVGGSVGV 75
Cdd:PRK13486    3 ITTLASVVIPCLGFSASsiAAAEDVMIVSASGYEKKLTNAAASVSvISQEELQSSQYHDLAEALRsvEGVDVESGTGKTG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  76 AQKIYIRGVEDSLLNITVDGAQQ------TSTLFHHIGRVTIDP-DLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQD 148
Cdd:PRK13486   83 GLEISIRGMPASYTLILIDGVRQggssdvTPNGFSAMNTGFMPPlAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNAD 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 149 llnqgeqfggrvKASYFSNDGTRLSTSvygklsDTWGVLGYFSTVDRENMEDGDGD-TIYGTAADQDMMFIKAsgeLADN 227
Cdd:PRK13486  163 ------------KWLSSVNAGLNLQES------NKWGNSSQFNFWSSGPLVDDSVSlQVRGSTQQRQGSSVTS---LSDT 221
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 228 HHLSISIEKRDEEGDFSARPNWAVQEGDALYPS-EAERETY------VANYIFSHNNLLYLE----ATAYKTESSF---- 292
Cdd:PRK13486  222 AATRIPYPTESQNYNLGARLDWKASEQDVLWFDmDTTRQRYdnrdgqLGSLTGGYDRTLRYErnkiSAGYDHTFTFgtwk 301
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 293 ---------NGGR----------FAWLADIDTyglDIRNTSII----------DEHKFVYGVDYRNDEVSSGSA-AGAKE 342
Cdd:PRK13486  302 sylnwneteNKGRelvrsvlkrdKWGLAGQPR---ELKESNLIlnsllltplgESHLVTVGGEFQSSSMKDGVVlASTGE 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 343 NSEQGSvLGVYAQGYSDITPQLLLSYGVRFDSYkfkqdilldEYYGTAITESASslddnelsfnigLAYDINDAWT---- 418
Cdd:PRK13486  379 TFRQKS-WSVFAEDEWHLTDALALTAGSRYEHH---------EQFGGHFSPRAY------------LVWDVADAWTlkgg 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 419 VGLGYAEAARGkQIGDGftIDGYLYDGSDIPVADESLVPETVANIEASITYTNEN-LSAKAS---------IYNSSLDDv 488
Cdd:PRK13486  437 VTTGYKAPRMG-QLHKG--ISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNPAgLNANVTgfmtdfsnkIVSYSIND- 512
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 489 ifegyeGNSVYNNIGTLETKGFEFDLAYRLNSFDFFIGFSATDTELDPRDglysvsydaidingyefvglGNSRGNTWVA 568
Cdd:PRK13486  513 ------NTNSYVNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRD--------------------GDNKGAPLSY 566
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 569 GVDYDINtdAKVGFSVTKvdslDINTLHQAVDLGWT-------DSLYTLNKPSY----------TTVDLYGQWNVTNALL 631
Cdd:PRK13486  567 TPEHMVN--AKLNWQITE----EVASWLGARYRGKTprftqnySSLSAVQKKVYdekgeylkawTVVDAGLSWKMTDALT 640
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1889613895 632 FNVAVTNLFNELYIDHS---------SVGDYSEVFGTVVGPYESGRDIRLSISYQF 678
Cdd:PRK13486  641 LNAAVNNLLNKDYSDVSlysagkstlYAGDYFQTGSSTTGYVIPERNYWMSLNYQF 696
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
7-642 3.67e-10

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 63.10  E-value: 3.67e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   7 MSAICASFSSPIYAQELAKntasVEKISVVGS----------ATNLSITAEEIEQYQASDLADIFRhSPSVSVGGSVGVA 76
Cdd:PRK13484   11 IAVMCSAVISSGYASSDKK----EDTLVVTASgftqqlrnapASVSVITSEQLQKKPVSDLVDAVK-DVEGISITGGNEK 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  77 QKIYIRGVEDSLLNITVDGAQQTSTLFHHIGRVT-----IDP-DLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQDLL 150
Cdd:PRK13484   86 PDISIRGLSGDYTLILVDGRRQSGRESRPNGSGGfeagfIPPvEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNNQT 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 151 NQGE-QFGGRVKASYFSNDGTRLSTSVYGKL-SDTWGVLGYFSTVDRENmedgdgDTI-YGTAAdQDMMFIKASGELADN 227
Cdd:PRK13484  166 WDGVlGLGGIIQEHGKFGNSTTNDFYLSGPLiKDKLGLQLYGGMNYRKE------DSIsQGTPA-KDNKNITATLQFTPT 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 228 HHLSISIEKRDEEGDFSARPNWAVQE----GDALYPSEaERETY--VANYIFSHNN---LLYLEATAY--------KTES 290
Cdd:PRK13484  239 ESQKFVFEYGKNNQVHTLTPGESLDAwtmrGNLKQPNS-KRETHnsRSHWVAAWNAqgeILHPEIAVYqekvirevKSGK 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 291 --SFNGGRFAWLA---DIDTYGLDIRNTSIIDEHKFVYGVDYRNDEVSSGSAAGAKEnSEQGSVL----GVYAQGYSDIT 361
Cdd:PRK13484  318 kdKYNHWDLNYESrkpEITNTIIDAKVTAFLPENVLTIGGQFQHAELRDDSATGKKT-TETQSVSikqkAVFIENEYAAT 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 362 PQLLLSYGVRFDSYkfkqdilldEYYGTAITESASSLddnelsfniglaYDINDAWTVGLGYAEAARG---KQIGDGFti 438
Cdd:PRK13484  397 DSLALTGGLRLDNH---------EIYGSYWNPRLYAV------------YNLTDNLTLKGGIAKAFRApsiREVSPGF-- 453
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 439 dGYLYD-GSDIPVADESLVPETVANIEASITYTNEN-LSAKASIYNSSLDDVIFEGYEGNS---------VYNNIGTLET 507
Cdd:PRK13484  454 -GTLTQgGASIMYGNRDLKPETSVTEEIGIIYSNDSgFSASATLFNTDFKNKLTSYDIGTKdpvtglntfIYDNVGEANI 532
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 508 KGFEfdLAYRLNSFDFFiGFSATDTELDPRDGLYSVSYDAIDINGYEFVGLGNSRGNtwvAGVDYDINTD----AKVGFS 583
Cdd:PRK13484  533 RGVE--LATQIPVYDKW-HVSANYTFTDSRRKSDDESLNGKSLKGEPLERTPRHAAN---AKLEWDYTQDitfySSLNYT 606
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1889613895 584 VTKVDSLDINtlhqavdlGWTDSLYtlnKPSYTTVDLYGQWNVTNALLFNVAVTNLFNE 642
Cdd:PRK13484  607 GKQIWAAQRN--------GAKVPRV---RNGFTSMDIGLNYQILPDTLINFAVLNVTDR 654
PRK13483 PRK13483
ligand-gated channel protein;
1-678 8.76e-09

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 58.63  E-value: 8.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   1 MKKLALMSAICASFSSPIYAQelAKNTASVEKISVVGS----------ATNLSITAEEIEQYQASDLADIFRHSPSVSVG 70
Cdd:PRK13483    6 AQVISALCLLPAVFVTHALAQ--AAPDKTMETVVVTASgyeqqirdapASISVITREDLENRFYRDLTDALLDVPGVVVT 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  71 GSVGVaQKIYIRGVEDSLLNITVDGAQQTStlfhhigRVT--------ID----PDL--LQQIDVQAGAGEATSGPGAIG 136
Cdd:PRK13483   84 GGGDR-TDISLRGMGSQYTLILVDGKRQSS-------RETrpnsdgpgVEqawtPPLaaIERIEVIRGPMSSLYGSDAIG 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 137 GSIRFKT-KDAQDLlnQGE-QFGGRVKASyfSNDGTRLSTSVY--GKL-SDTWGVLGYFSTVDRENmedgdgDTIYGTAA 211
Cdd:PRK13483  156 GVINIITrKVPNEW--QGEvRLDTTLQEN--SDSGNVYQANFFvnGPLiKDLLGLQLYGQYTQREE------DDIEGGYR 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 212 DQDMMFIKASGELADNHHLSISIE------KRDEEGDFSARPNWAVQE-GDALYPSEAERETYVANYIFSHN-NLLYLEA 283
Cdd:PRK13483  226 DKDARSLTAKLALTPNEDHDIMLEvgtsnqERDSTVGKTVAPLAPGEScGRRGCPESSTTEYERSTVSLSHTgRWDFGTS 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 284 TAY-KTESSFNGGRfawlaDIDTYGLDIRNTSII---DEHKFVYGVDYR----NDEVSSGSAAGAKENSEQGSvlgVYAQ 355
Cdd:PRK13483  306 DTYiQHEEFDNKSR-----EMKIKNTDFQSSLVAplgQEHTLTFGAAYNhqdlTDETSNQISDLTDISRTQWA---VFSE 377
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 356 GYSDITPQLLLSYGVRFDSykfkqdillDEYYGtaitesasslddNELSFNIGLAYDINDAWTVGLGYAEAARGK----- 430
Cdd:PRK13483  378 DEWRIADDFALTGGLRLDH---------DENFG------------GHVSPRVYGVWNLAPSWTVKGGVSTGFRAPslrqt 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 431 -----QIGDGftidGYLYDGSDipvadesLVPETVANIEASITY-TNENLSAKASIYNSSLDDVIF-------------- 490
Cdd:PRK13483  437 tpdwgQVSRG----GNIYGNPD-------LKPETSLNKELGLYYdLGSGLTASLTVFYNEFKDKITrvacpatqctdgpn 505
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 491 EGYEGNSVYNNIGTLETKGFEFDLAYRLNSFDFFIGfSATDTELDPRDGLY---------------SVSYDAIDingyef 555
Cdd:PRK13483  506 QFGADPTTYVNIDEAVTQGVEASLSYPITSTLSLSG-NYTYTDSEQKSGAYkgsplnqlpkhlfqaSLNWEPTD------ 578
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 556 vglgnsRGNTWvAGVDYDINTDAKVGfsvtkvdsldintlhqavdlGWTDSlyTLNKPSYTTVDLYGQWNVTNALLFNVA 635
Cdd:PRK13483  579 ------RLNSW-ARVNYRGEESQPTT--------------------GPSSS--SFIAPSYTFLDLGANYQLTDNLKLSAG 629
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|...
gi 1889613895 636 VTNLFNELYidhssvgDYSEvFGTVvgpyESGRDIRLSISYQF 678
Cdd:PRK13483  630 IYNLFDKEI-------NYEE-YGYV----EDGRRYWLGMTYSF 660
PRK14050 PRK14050
TonB-dependent siderophore receptor;
80-675 4.67e-06

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 49.80  E-value: 4.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  80 YIRGVEDSLLNITVDGAQQTSTLFhhiGRVTIDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDAQD---------LL 150
Cdd:PRK14050  125 YIRGFDATQTGVFLDGLNLFSYGF---GGFQIDPFMLERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDeplyyteigIN 201
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 151 NQGEQFGGRVKASYFSNDGT---RLSTSVYG--KLSD-------------TWG--------VLGYFSTVDRenMEDGDGD 204
Cdd:PRK14050  202 SYGNAFTGFDVGDKLSDDGTvryRVTGKVAGgdNYSDysedlrgfimpqiTYApddatsltVYGYLSGLDQ--VHVGNGF 279
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 205 TIY-GTAADQDMMFIKAS---GEL-ADNHHLSISIEKRDEEGDFSArpNWAVQEgDALYPSEAERETYVANYIFSHNNLL 279
Cdd:PRK14050  280 LPYvGTVVDAPFGKIDRDafyGEPdIDNGSYAQQMLGYEFSHEFDN--GWTFSQ-NARYGHLHKHEKGPYTYGYVGGATG 356
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 280 YLEATAykteSSFNGGRFAWLAD--IDTYGLDIRNTSIID----EHKFVYGVDY---RNDEV--SSGSAAGAKENSEQGS 348
Cdd:PRK14050  357 LPDPTG----PDYMLNRIGFEHRskVDSFSIDNRLEGEFDtgalTHNLLFGLDYkyyRLDQVqaCCGATPISATNPVYGT 432
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 349 V----------------LGVYAQGYSDITPQLLLSYGVRFDSYKFKQDILLDEYYGTaitesasslDDNELSFNIGLAYD 412
Cdd:PRK14050  433 TqganfvyldqiltqqqIGIYAQDQIRFGDGWLVTLNGRYDYVDTDSDARIGTSYES---------NDGALSGRAGLAYE 503
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 413 INDAWTvglGYAEAAR--GKQIGDGftidgylydgsdipVADESLVPETVANIEASITYtnenlsaKASIYNSSLDDVIF 490
Cdd:PRK14050  504 FDNGLT---PYVSAATffNPLVGTL--------------ASGPPLKPEEGEQYEAGIKY-------EPSFIDGLITASVF 559
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 491 EGYEGNSVYNN--------IGTLETKGFEFDLAYRLN-SFDFFIGFSATDTEldprdglysVSYDA-IDINGYEFVGLGN 560
Cdd:PRK14050  560 QITKKNVTVTDpltfastqLGEVRSRGFELEGKVNLDdNWKALASFTYTDLE---------ITEDAnPSLIGNSPYLVPE 630
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 561 SRGNTWvagVDYDINTDAKVGFsvtkvdSLDINTLHQAVDlgWTDSLYTLNKPSYTTVDL---YGQWNVTNALlfnvAVT 637
Cdd:PRK14050  631 TQASLW---LDYAVTDGAFEGV------SLGAGVRYQGES--WADEANTLKVPAATLFDAairYEKNDWGASL----NVA 695
                         650       660       670
                  ....*....|....*....|....*....|....*...
gi 1889613895 638 NLFNELYIdhssvgdySEVFGTVVGPYESGRDIRLSIS 675
Cdd:PRK14050  696 NLFDKEYV--------AGCQGLLVCGYGESRTITLKLS 725
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
1-678 7.59e-05

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 46.03  E-value: 7.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   1 MKKLALMSAICASFSSPIYAQELAKNTASVEKISVVGSAT--NLS--------ITAEEIEQYQASDLADIFRHSPSVSVG 70
Cdd:PRK10064    1 MFRLNPFVRVGLCASAISCAWPVLAVDDDGETMVVTASAVeqNLKdapasisvITQEDLQRKPVQNLKDVLKEVPGVQLT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  71 GSVGVAQKIYIRGVEDSLLNITVDGAQQTST--LFHHIGRVT--IDPDLLQQIDVQAGAGEATSGPGAIGGSIRFKTKDA 146
Cdd:PRK10064   81 NEGDNRKGVSIRGLDSSYTLILIDGKRVNSRnaVFRHNDFDLnwIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 147 qdllnqGEQFGGRVKASYF------SNDGTRLSTSVYGKLSDtwGVLG---YFSTVDRENMEDGDGDTIYGTAADQDMMF 217
Cdd:PRK10064  161 ------GQKWHGTVTVDTTiqehrdRGDTYNGQFFTSGPLID--GVLGmkaYGSLAKREKDDPQNSTTTDTGETPRIEGF 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 218 IKASG--ELA----DNHHLSISIEKRDEEGDfsarpnwavqeGDALYPSEAEREtyvaNYIFSHNNLLYLEATAYKTE-- 289
Cdd:PRK10064  233 TSRDGnvEFAwtpnQNHDFTAGYGFDRQDRD-----------SDSLDKNRLERQ----NYSLSHNGRWDYGNSELKYYge 297
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 290 --SSFNGGRFAWLADiDTYGLDIRNTSIIDE--HKFVYGVDYRNDEVSSGSA-AGAKENSEQGSVLGVYAQGYSDITPQL 364
Cdd:PRK10064  298 kvENKNPGNSSPITS-ESNSIDGKYTLPLTAinQFLTFGGEWRHDKLSDAVNlTGGTSSKTSASQYALFVEDEWRIFEPL 376
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 365 LLSYGVRFDSYkfkqdilldEYYGtaitesasslddNELSFNIGLAYDINDAWTVGLGYAEAARGK---QIGDGFTIDGy 441
Cdd:PRK10064  377 ALTTGVRMDDH---------ETYG------------DHWSPRAYLVYNATDTVTVKGGWATAFKAPsllQLSPDWTSNS- 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 442 lYDGSDIPVADESLVPETVANIEASITYTNEnlsakasiynssldDVIFEGYEG------NSVYNNIGTLETKgfEFDLA 515
Cdd:PRK10064  435 -CRGACKIVGSPDLKPETSESWELGLYYMGE--------------EGWLEGVESsvtvfrNDVDDRISISRTS--DVNAA 497
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 516 yrlNSFDFFIGFSAT-DTELDPRDGLYSVsyDAIDINGYEfvglgnsrgntwvAGVDYDINTDAKVGFSVTKVDSLDINT 594
Cdd:PRK10064  498 ---PGYQNFVGFETNgRGRRVPVFRYYNV--NKARIQGVE-------------TELKIPFNDEWKLSLNYTYNDGRDVSN 559
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895 595 ----------LHQA-VDLGWTD------SLY--------------TLNKPS-YTTVDLYGQWNVTNALLFNVAVTNLFNE 642
Cdd:PRK10064  560 genkplsdlpFHTAnGTLDWKPlaledwSFYvsgnytgqkradsaTAKTPGgYTIWNTGAAWQVTKDVKLRAGVLNLGDK 639
                         730       740       750
                  ....*....|....*....|....*....|....*.
gi 1889613895 643 lyidHSSVGDYSEVfgtvvgpyESGRDIRLSISYQF 678
Cdd:PRK10064  640 ----DLSRDDYSYN--------EDGRRYFMAVDYRF 663
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
2-148 3.30e-04

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 43.83  E-value: 3.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895   2 KKLALMSAICAS-FSSpiYAQELAKNTASV------EKISVVGSATNLsITAEEIEQYQASDLADIFRHSPSVSVGGSVG 74
Cdd:PRK10641    3 KKASLLTALSVTaFSG--WAQDTSPDTLVVtanrfqQPVSTVLAPTTV-VTRDDIDRWQSKSVNDVLRRLPGVDIAQNGG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889613895  75 VAQK--IYIRGVEDSLLNITVDGAQQTSTlfhhigRVTIDPD-------LLQQIDVQAGAGEATSGPGAIGGSIRFKTKD 145
Cdd:PRK10641   80 LGQLssLFIRGTNSSHVLVLIDGVRLNQA------GISGSADlsqipisLVQRIEYIRGPRSAVYGSDAIGGVVNIITTR 153

                  ...
gi 1889613895 146 AQD 148
Cdd:PRK10641  154 DKP 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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