|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1043 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1093.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 1 MKFSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 81 FSQgTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPekTHDTAYLSNYA 160
Cdd:COG0841 81 TST-SSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSD--DLDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 161 DLNIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQpisndsQFQILLNVK 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGG------DREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 241 GRLNSIEEFEQVIIKVGDeGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNF 320
Cdd:COG0841 232 GRLKTPEEFENIVIRTND-GSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 321 PTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFG 400
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 401 LVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITIST 480
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 481 IISAFNSLTLSPALAALLLKSHDAKPDaftrllnklfgRWLFKPFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVGG 560
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKK-----------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 561 TIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLSvnGFTNSPNSGIVFTPL 640
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFS--GGGSGSNSGTIFVTL 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 641 ESFDKRTdpsQSAMAIAAQLNKRFAAIDEAFVAVFPPPPiQGLGTTGGFKLQIEDRankGFEALFNSLQAVIGKAQQDPA 720
Cdd:COG0841 618 KPWDERD---RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQGD---DLEELAAAAEKLLAALRQIPG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 721 LMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLKVR 800
Cdd:COG0841 691 LVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVR 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 801 NRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLAD-TLPTGIEYEWTEVTYQQVLAG 879
Cdd:COG0841 771 TPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESF 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 880 NTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFAK 959
Cdd:COG0841 851 SSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFAN 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 960 DRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLVTN 1039
Cdd:COG0841 931 QLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDR 1010
|
....
gi 1889614193 1040 KKEK 1043
Cdd:COG0841 1011 LRRR 1014
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1037 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1037.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 3 FSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 83 QgTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADL 162
Cdd:pfam00873 81 Q-SSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 163 NIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLgaqpisNDSQFQILLNVKGR 242
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 243 LNSIEEFEQVIIKVGDeGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPT 322
Cdd:pfam00873 234 LQSAEDFEKIIVKNQD-GSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 323 GVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLV 402
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 403 LAIGIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTI 481
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLeENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 482 ISAFNSLTLSPALAALLLKSHDAKPDaftrllnklfgRWLFKPFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVGGT 561
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH-----------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 562 IKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLSVNGFTNSPNSGIVFTPLE 641
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLK 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 642 SFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIED-RANKGFEALFNSLQAVIGKAQQDPA 720
Cdd:pfam00873 622 PWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 721 LMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLKVR 800
Cdd:pfam00873 702 LSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 801 NRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLAD-TLPTGIEYEWTEVTYQQVLAG 879
Cdd:pfam00873 782 NPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvKLPPGYGYTWTGQFEQEQLAG 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 880 NTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFAK 959
Cdd:pfam00873 862 NSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFAN 941
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1889614193 960 D-RHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLV 1037
Cdd:pfam00873 942 ElREQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1049 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1001.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 3 FSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 83 QGTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 163 NIKDEIARLPGVGDIRMFGAgKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDSQFQILLNVKGR 242
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 243 LNSIEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPT 322
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 323 GVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLV 402
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 403 LAIGIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTI 481
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 482 ISAFNSLTLSPALAALLLKSHD--AKPDAFTRLLNklfgrWlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVG 559
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKPIEkgEHHEKKGGFFG-----W----FNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVG 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 560 GTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFpglSVNGFT---NSPNSGIV 636
Cdd:TIGR00915 551 GMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVF---TVNGFSfagRGQNMGMA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 637 FTPLESFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQ 716
Cdd:TIGR00915 628 FIRLKDWEERTGKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 717 QDPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILN 796
Cdd:TIGR00915 708 QNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINK 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 797 LKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKvLADTLPTGIEYEWTEVTYQQV 876
Cdd:TIGR00915 788 WYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEA-IAQKLPPGFGFSWTGMSYEER 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 877 LAGNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVE 956
Cdd:TIGR00915 867 LSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVE 946
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 957 FAKDRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYML 1036
Cdd:TIGR00915 947 FAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVV 1026
|
1050
....*....|....*.
gi 1889614193 1037 VTN---KKEKAQENTH 1049
Cdd:TIGR00915 1027 VRRlfkRKAHEKEMSV 1042
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
6-1047 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 774.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 6 FFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQGT 85
Cdd:PRK15127 4 FFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 86 SDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADLNIK 165
Cdd:PRK15127 84 STGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 166 DEIARLPGVGDIRMFGAgKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDSQFQILLNVKGRLNS 245
Cdd:PRK15127 164 DPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 246 IEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPTGVE 325
Cdd:PRK15127 243 TEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 326 YDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLVLAI 405
Cdd:PRK15127 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 406 GIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTIISA 484
Cdd:PRK15127 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 485 FNSLTLSPALAALLLK-----SHDAKPDAFtrllnklFGrWlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVG 559
Cdd:PRK15127 483 LVALILTPALCATMLKpiakgDHGEGKKGF-------FG-W----FNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVV 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 560 GTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIAL--EVPGVAHTVAFPGLSVNGftNSPNSGIVF 637
Cdd:PRK15127 551 GMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLtkEKNNVESVFAVNGFGFAG--RGQNTGIAF 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 638 TPLESFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQQ 717
Cdd:PRK15127 629 VSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAK 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 718 DP-ALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILN 796
Cdd:PRK15127 709 HPdMLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGD 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 797 LKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKvLADTLPTGIEYEWTEVTYQQV 876
Cdd:PRK15127 789 WYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEE-LASKLPTGVGYDWTGMSYQER 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 877 LAGNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVE 956
Cdd:PRK15127 868 LSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVE 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 957 FAKDRHD-SGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYM 1035
Cdd:PRK15127 948 FAKDLMDkEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFV 1027
|
1050
....*....|..
gi 1889614193 1036 LVTNKKEKAQEN 1047
Cdd:PRK15127 1028 VVRRRFSRKNED 1039
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1037 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 712.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 4 SHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQ 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 84 gTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDL-TMVVHLYSPEKthDTAYLSNYADL 162
Cdd:NF033617 81 -SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTpIMYIGLTSEEM--PRGQLTDYAER 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 163 NIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQ----PISNDSQfqilln 238
Cdd:NF033617 158 VLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDsvvsTVRANDQ------ 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 239 vkgrLNSIEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSK 318
Cdd:NF033617 232 ----LKTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 319 NFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSL 398
Cdd:NF033617 308 TLPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 399 FGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITI 478
Cdd:NF033617 388 MALVLAIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAG 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 479 STIISAFNSLTLSPALAALLLKSHDaKPDAFTRLlnklfgrwlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALV 558
Cdd:NF033617 468 AVIISGIVALTLTPMMCSRLLKANE-KPGRFARA------------VDRFFDGLTARYGRGLKWVLKHRPLTLVVALATL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 559 GGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLsvnGFTNSPNSGIVFT 638
Cdd:NF033617 535 ALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGV---GGNPGDNTGFGII 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 639 PLESFDKRTDpsqSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGlGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQQD 718
Cdd:NF033617 612 NLKPWDERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKS 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 719 PALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLK 798
Cdd:NF033617 688 PQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIY 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 799 VRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLADTLPTGIEYEWTEVTYQQVLA 878
Cdd:NF033617 768 VRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEE 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 879 GNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFA 958
Cdd:NF033617 848 GSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFA 927
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 959 KD-RHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLV 1037
Cdd:NF033617 928 NElQRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1043 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1093.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 1 MKFSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 81 FSQgTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPekTHDTAYLSNYA 160
Cdd:COG0841 81 TST-SSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSD--DLDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 161 DLNIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQpisndsQFQILLNVK 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGG------DREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 241 GRLNSIEEFEQVIIKVGDeGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNF 320
Cdd:COG0841 232 GRLKTPEEFENIVIRTND-GSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 321 PTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFG 400
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 401 LVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITIST 480
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 481 IISAFNSLTLSPALAALLLKSHDAKPDaftrllnklfgRWLFKPFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVGG 560
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKK-----------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 561 TIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLSvnGFTNSPNSGIVFTPL 640
Cdd:COG0841 540 SVLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFS--GGGSGSNSGTIFVTL 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 641 ESFDKRTdpsQSAMAIAAQLNKRFAAIDEAFVAVFPPPPiQGLGTTGGFKLQIEDRankGFEALFNSLQAVIGKAQQDPA 720
Cdd:COG0841 618 KPWDERD---RSADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQGD---DLEELAAAAEKLLAALRQIPG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 721 LMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLKVR 800
Cdd:COG0841 691 LVDVRSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVR 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 801 NRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLAD-TLPTGIEYEWTEVTYQQVLAG 879
Cdd:COG0841 771 TPDGEMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESF 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 880 NTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFAK 959
Cdd:COG0841 851 SSLGLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFAN 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 960 DRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLVTN 1039
Cdd:COG0841 931 QLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDR 1010
|
....
gi 1889614193 1040 KKEK 1043
Cdd:COG0841 1011 LRRR 1014
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1037 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1037.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 3 FSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 83 QgTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADL 162
Cdd:pfam00873 81 Q-SSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 163 NIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLgaqpisNDSQFQILLNVKGR 242
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 243 LNSIEEFEQVIIKVGDeGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPT 322
Cdd:pfam00873 234 LQSAEDFEKIIVKNQD-GSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 323 GVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLV 402
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 403 LAIGIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTI 481
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLeENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 482 ISAFNSLTLSPALAALLLKSHDAKPDaftrllnklfgRWLFKPFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVGGT 561
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH-----------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGS 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 562 IKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLSVNGFTNSPNSGIVFTPLE 641
Cdd:pfam00873 542 VWLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLK 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 642 SFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIED-RANKGFEALFNSLQAVIGKAQQDPA 720
Cdd:pfam00873 622 PWKERPGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 721 LMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLKVR 800
Cdd:pfam00873 702 LSDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 801 NRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLAD-TLPTGIEYEWTEVTYQQVLAG 879
Cdd:pfam00873 782 NPYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvKLPPGYGYTWTGQFEQEQLAG 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 880 NTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFAK 959
Cdd:pfam00873 862 NSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFAN 941
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1889614193 960 D-RHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLV 1037
Cdd:pfam00873 942 ElREQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLF 1020
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1049 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1001.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 3 FSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 83 QGTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 163 NIKDEIARLPGVGDIRMFGAgKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDSQFQILLNVKGR 242
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 243 LNSIEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPT 322
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 323 GVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLV 402
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 403 LAIGIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTI 481
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 482 ISAFNSLTLSPALAALLLKSHD--AKPDAFTRLLNklfgrWlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVG 559
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKPIEkgEHHEKKGGFFG-----W----FNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVG 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 560 GTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFpglSVNGFT---NSPNSGIV 636
Cdd:TIGR00915 551 GMVFLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVF---TVNGFSfagRGQNMGMA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 637 FTPLESFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQ 716
Cdd:TIGR00915 628 FIRLKDWEERTGKENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 717 QDPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILN 796
Cdd:TIGR00915 708 QNPALTRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINK 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 797 LKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKvLADTLPTGIEYEWTEVTYQQV 876
Cdd:TIGR00915 788 WYVRNASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEA-IAQKLPPGFGFSWTGMSYEER 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 877 LAGNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVE 956
Cdd:TIGR00915 867 LSGSQAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVE 946
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 957 FAKDRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYML 1036
Cdd:TIGR00915 947 FAKELMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVV 1026
|
1050
....*....|....*.
gi 1889614193 1037 VTN---KKEKAQENTH 1049
Cdd:TIGR00915 1027 VRRlfkRKAHEKEMSV 1042
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
6-1047 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 774.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 6 FFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQGT 85
Cdd:PRK15127 4 FFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 86 SDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADLNIK 165
Cdd:PRK15127 84 STGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 166 DEIARLPGVGDIRMFGAgKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDSQFQILLNVKGRLNS 245
Cdd:PRK15127 164 DPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 246 IEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPTGVE 325
Cdd:PRK15127 243 TEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 326 YDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLVLAI 405
Cdd:PRK15127 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 406 GIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTIISA 484
Cdd:PRK15127 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 485 FNSLTLSPALAALLLK-----SHDAKPDAFtrllnklFGrWlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVG 559
Cdd:PRK15127 483 LVALILTPALCATMLKpiakgDHGEGKKGF-------FG-W----FNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVV 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 560 GTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIAL--EVPGVAHTVAFPGLSVNGftNSPNSGIVF 637
Cdd:PRK15127 551 GMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLtkEKNNVESVFAVNGFGFAG--RGQNTGIAF 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 638 TPLESFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQQ 717
Cdd:PRK15127 629 VSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAK 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 718 DP-ALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILN 796
Cdd:PRK15127 709 HPdMLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGD 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 797 LKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKvLADTLPTGIEYEWTEVTYQQV 876
Cdd:PRK15127 789 WYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEE-LASKLPTGVGYDWTGMSYQER 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 877 LAGNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVE 956
Cdd:PRK15127 868 LSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVE 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 957 FAKDRHD-SGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYM 1035
Cdd:PRK15127 948 FAKDLMDkEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFV 1027
|
1050
....*....|..
gi 1889614193 1036 LVTNKKEKAQEN 1047
Cdd:PRK15127 1028 VVRRRFSRKNED 1039
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
4-1037 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 770.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 4 SHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQ 83
Cdd:PRK10555 2 ANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 84 GTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADLN 163
Cdd:PRK10555 82 SSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 164 IKDEIARLPGVGDIRMFGAgKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDSQFQILLNVKGRL 243
Cdd:PRK10555 162 IQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 244 NSIEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPTG 323
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 324 VEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLVL 403
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 404 AIGIVVDDAIVVVENVERNI-EKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTII 482
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 483 SAFNSLTLSPALAALLLK-----SHDAKpdaftrllnKLFGRWlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIAL 557
Cdd:PRK10555 481 SVLVAMILTPALCATLLKplkkgEHHGQ---------KGFFGW----FNRMFNRNAERYEKGVAKILHRSLRWILIYVLL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 558 VGGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALE-----VPGVAHTV-AFPGlsvngfTNSP 631
Cdd:PRK10555 548 LGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFThekdnVMSVFATVgSGPG------GNGQ 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 632 NSGIVFTPLESFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIEDRANKGFEALFNSLQAV 711
Cdd:PRK10555 622 NVARMFIRLKDWDERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 712 IGKAQQDPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDP 791
Cdd:PRK10555 702 LALAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLP 781
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 792 DQILNLKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKvLADTLPTGIEYEWTEV 871
Cdd:PRK10555 782 DDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMES-LVKQLPNGFGLEWTAM 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 872 TYQQVLAGNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNA 951
Cdd:PRK10555 861 SYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNA 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 952 ILMVEFAKDRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTP 1031
Cdd:PRK10555 941 ILIVEFANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVP 1020
|
....*.
gi 1889614193 1032 VFYMLV 1037
Cdd:PRK10555 1021 LFFVLV 1026
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
6-1037 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 738.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 6 FFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMfSQGT 85
Cdd:PRK09577 4 FFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYT-SATS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 86 SDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHDTAYLSNYADLNIK 165
Cdd:PRK09577 83 SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASANVL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 166 DEIARLPGVGDIRMFGAgKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDSQFQILLNVKGRLNS 245
Cdd:PRK09577 163 QALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPLKT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 246 IEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSKNFPTGVE 325
Cdd:PRK09577 242 PEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 326 YDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLVLAI 405
Cdd:PRK09577 322 YQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 406 GIVVDDAIVVVENVER-NIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITISTIISA 484
Cdd:PRK09577 402 GILVDDAIVVVENVERlMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSA 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 485 FNSLTLSPALAALLLKSHDAkpDAFTRllnklfgRWLFKPFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALVGGTIKL 564
Cdd:PRK09577 482 FLALSLTPALCATLLKPVDG--DHHEK-------RGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 565 FDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLSVNGftNSPNSGIVFTPLESFD 644
Cdd:PRK09577 553 FTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYG--EGPNGGMIFVTLKDWK 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 645 KRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQQDPALMGL 724
Cdd:PRK09577 631 ERKAARDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDL 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 725 YSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLKVRNRSG 804
Cdd:PRK09577 711 MFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQG 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 805 NMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKvLADTLPTGIEYEWTEVTYQQVLAGNTMVY 884
Cdd:PRK09577 791 EMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIER-IAATLPAGIGYAWSGQSFEERLSGAQAPM 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 885 VFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFAKDRHDS 964
Cdd:PRK09577 870 LFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQ 949
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1889614193 965 GLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLV 1037
Cdd:PRK09577 950 RMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1037 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 712.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 4 SHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQ 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 84 gTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDL-TMVVHLYSPEKthDTAYLSNYADL 162
Cdd:NF033617 81 -SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTpIMYIGLTSEEM--PRGQLTDYAER 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 163 NIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQ----PISNDSQfqilln 238
Cdd:NF033617 158 VLAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDsvvsTVRANDQ------ 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 239 vkgrLNSIEEFEQVIIKVGDEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLSK 318
Cdd:NF033617 232 ----LKTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 319 NFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLSL 398
Cdd:NF033617 308 TLPKNIKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 399 FGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTITI 478
Cdd:NF033617 388 MALVLAIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAG 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 479 STIISAFNSLTLSPALAALLLKSHDaKPDAFTRLlnklfgrwlfkpFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIALV 558
Cdd:NF033617 468 AVIISGIVALTLTPMMCSRLLKANE-KPGRFARA------------VDRFFDGLTARYGRGLKWVLKHRPLTLVVALATL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 559 GGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGLsvnGFTNSPNSGIVFT 638
Cdd:NF033617 535 ALLPLLYVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGV---GGNPGDNTGFGII 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 639 PLESFDKRTDpsqSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGlGTTGGFKLQIEDRANKGFEALFNSLQAVIGKAQQD 718
Cdd:NF033617 612 NLKPWDERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG-GAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKS 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 719 PALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNLK 798
Cdd:NF033617 688 PQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIY 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 799 VRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLADTLPTGIEYEWTEVTYQQVLA 878
Cdd:NF033617 768 VRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEE 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 879 GNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFA 958
Cdd:NF033617 848 GSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFA 927
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 959 KD-RHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLV 1037
Cdd:NF033617 928 NElQRHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1045 |
1.75e-149 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 471.63 E-value: 1.75e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 1 MKFSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 81 fsqgTSDGRM---TLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVAEKSSPDLTMVVHLYSPEKTHdtAYLS 157
Cdd:PRK09579 81 ----TSVSRQnfsIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSEEMSN--PQIT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 158 NYADLNIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISNDsqfqilL 237
Cdd:PRK09579 155 DYLSRVIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTS------I 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 238 NVKGRLNSIEEFEQVIIKVGDEGQLtRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLS 317
Cdd:PRK09579 229 NASTELKSAEAFAAIPVKTSGDSRV-LLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELE 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 318 KNFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLS 397
Cdd:PRK09579 308 SQLPPNLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLT 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 398 LFGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTIT 477
Cdd:PRK09579 388 LLAMVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLA 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 478 ISTIISAFNSLTLSPALAALLLKsHDAKPDAFTRLLnklfgrwlfkpfNRVFNRGAKGYEKLVQKLIRMTVVVMVAYIAL 557
Cdd:PRK09579 468 GAVIISGIVALTLSPMMCALLLR-HEENPSGLAHRL------------DRLFERLKQRYQRALHGTLNTRPVVLVFAVIV 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 558 VGGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVahtvaFPGLSVNGFtNSPNSGIVF 637
Cdd:PRK09579 535 LALIPVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEY-----YSSFQINGF-NGVQSGIGG 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 638 TPLESFDKRtdpSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTtgGFKLQIEDRANKGFEALFNSLQAVIGKAQQ 717
Cdd:PRK09579 609 FLLKPWNER---ERTQMELLPLVQAKLEEIPGLQIFGFNLPSLPGTGE--GLPFQFVINTANDYESLLQVAQRVKQRAQE 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 718 DPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADADYRLDPDQILNL 797
Cdd:PRK09579 684 SGKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNY 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 798 KVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPApgYSSDQAQVAIEKVLADTLPTGIEYEWTEVTYQQVL 877
Cdd:PRK09579 764 YVKNEQGQLLPLSTLITLSDRARPRQLNQFQQLNSAIISGFPI--VSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQ 841
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 878 AGNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEF 957
Cdd:PRK09579 842 EGSALWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEF 921
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 958 AKD-RHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYML 1036
Cdd:PRK09579 922 ANQlRHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTL 1001
|
....*....
gi 1889614193 1037 VTNKKEKAQ 1045
Cdd:PRK09579 1002 LAKPDAAPG 1010
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
4-1036 |
5.69e-117 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 385.62 E-value: 5.69e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 4 SHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQ 83
Cdd:PRK10503 13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 84 gTSDGRMTLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGV---VAEKSSPDLTMVVhlyspekTHDTAYLSNYA 160
Cdd:PRK10503 93 -SSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVyskVNPADPPIMTLAV-------TSTAMPMTQVE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 161 DL---NIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLGAQPISndsqfqILL 237
Cdd:PRK10503 165 DMvetRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRA------VTL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 238 NVKGRLNSIEEFEQVIIKVGDeGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVRETMARLS 317
Cdd:PRK10503 239 SANDQMQSAEEYRQLIIAYQN-GAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 318 KNFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLS 397
Cdd:PRK10503 318 ESLPKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLT 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 398 LFGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALTIT 477
Cdd:PRK10503 398 LMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 478 ISTIISAFNSLTLSPALAALLLKSHD-AKPDAFTRllnklfgrwlfkPFNRVFNRGAKGYEKLVQKLIR---MTVVVMVA 553
Cdd:PRK10503 478 VAILISAVVSLTLTPMMCARMLSQESlRKQNRFSR------------ASERMFDRVIAAYGRGLAKVLNhpwLTLSVALS 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 554 YIALvggTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFPGlsVNGFTNSPNS 633
Cdd:PRK10503 546 TLLL---TVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG--VDGTNPSLNS 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 634 GIVFTPLESFDKRTDPSQsamAIAAQLNKRFAAIDEAFVAVfppPPIQGLG-------TTGGFKLQiedraNKGFEALFN 706
Cdd:PRK10503 621 ARLQINLKPLDERDDRVQ---KVIARLQTAVAKVPGVDLYL---QPTQDLTidtqvsrTQYQFTLQ-----ATSLDALST 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 707 SLQAVIGKAQQDPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADAD 786
Cdd:PRK10503 690 WVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 787 YRLDPDQILNLKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAI---EKVLAdtLPTG 863
Cdd:PRK10503 770 NTPGLAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAImdtEKTLN--LPAD 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 864 I--EYEWTEVTYQQVLaGNTmVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALI 941
Cdd:PRK10503 848 IttQFQGSTLAFQSAL-GST-VWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGII 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 942 VLVALASKNAILMVEFA-KDRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMI 1020
Cdd:PRK10503 926 LLIGIVKKNAIMMIDFAlAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLI 1005
|
1050
....*....|....*.
gi 1889614193 1021 GVTVFGLLFTPVFYML 1036
Cdd:PRK10503 1006 VSQVLTLFTTPVIYLL 1021
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
1-1050 |
1.58e-107 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 359.43 E-value: 1.58e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 1 MKFSHFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQ---EINGTENM 77
Cdd:PRK10614 1 MKFFALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERslgRIAGVNEM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 78 LYMFSQGTSdgRMTLTvtFALGTDLDRAQVQVQNRVNSALPRLPEEVQRLGVVaEKSSPDLTMVVHLYSPEKTHDTAYLS 157
Cdd:PRK10614 81 TSSSSLGST--RIILQ--FDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTY-RKANPSDAPIMILTLTSDTYSQGQLY 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 158 NYADLNIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLgaqpisNDSQFQILL 237
Cdd:PRK10614 156 DFASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAV------EDGTHRWQI 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 238 NVKGRLNSIEEFEQVIIKVGDeGQLTRLSDIARV-DLGQDTYAlrAELDN-QPALAMPIFQRPGSNAIELSDQVRETMAR 315
Cdd:PRK10614 230 QTNDELKTAAEYQPLIIHYNN-GAAVRLGDVATVtDSVQDVRN--AGMTNaKPAILLMIRKLPEANIIQTVDRIRAKLPE 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 316 LSKNFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINT 395
Cdd:PRK10614 307 LRETIPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNN 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 396 LSLFGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGLSGQFYKQFALT 475
Cdd:PRK10614 387 LSLMALTIATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVT 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 476 ITISTIISAFNSLTLSPALAALLLKSHdaKPDAFTRLlnklfgrwlfKPFNRVFNRGAKGYEKLVQKLIRMTVVVMVAYI 555
Cdd:PRK10614 467 LSVAIGISLLVSLTLTPMMCAWLLKSS--KPREQKRL----------RGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLL 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 556 ALVGGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAhtvafpglSVNGFT--NSPNS 633
Cdd:PRK10614 535 GTIALNVWLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVD--------NVTGFTggSRVNS 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 634 GIVFTPLESFDKRTDpsqSAMAIAAQLNKRFAaiDEAFVAVFpPPPIQGLGTTGGfklqiEDRANKGFEALFNSLQA--- 710
Cdd:PRK10614 607 GMMFITLKPLSERSE---TAQQVIDRLRVKLA--KEPGANLF-LMAVQDIRVGGR-----QSNASYQYTLLSDDLAAlre 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 711 ---VIGKA-QQDPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGRTYQVNAQADAD 786
Cdd:PRK10614 676 wepKIRKAlAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPR 755
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 787 YRLDPDQILNLKVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYPSAELNGSPAPGYSSDQAQVAIEKVLAD-TLPTGI- 864
Cdd:PRK10614 756 YTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQlGVPSTVr 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 865 -EYEWTEVTYQQVLagNTMVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGV-WFvgsdNNIFTQIALI- 941
Cdd:PRK10614 836 gSFAGTAQVFQETM--NSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALeLF----NAPFSLIALIg 909
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 942 --VLVALASKNAILMVEFAKDRHDSG-LSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSG 1018
Cdd:PRK10614 910 imLLIGIVKKNAIMMVDFALEAQRNGnLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGG 989
|
1050 1060 1070
....*....|....*....|....*....|..
gi 1889614193 1019 MIGVTVFGLLFTPVFYMLVTNKKEKAQENTHD 1050
Cdd:PRK10614 990 LVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQ 1021
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
5-1047 |
1.81e-106 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 356.65 E-value: 1.81e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 5 HFFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEINGTENMLYMFSQ- 83
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIs 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 84 --GTSDgrmtLTVTFALGTDLDRAQVQVQNRVNSALPRLPEEVQ-RLGvvaekssPDLT------MVVhLYSPEKTHDTA 154
Cdd:COG3696 87 rfGLSV----VTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTpELG-------PISTglgeiyQYT-LESDPGKYSLM 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 155 YLSNYADLNIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLgaqpisNDSQFQ 234
Cdd:COG3696 155 ELRTLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYI------ERGGQE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 235 ILLNVKGRLNSIEEFEQVIIKVGDeGQLTRLSDIARVDLGqdtYALR---AELD-NQPALAMPIFQRPGSNAIELSDQVR 310
Cdd:COG3696 229 YLVRGIGLIRSLEDIENIVVKTRN-GTPVLLRDVAEVRIG---PAPRrgaATLNgEGEVVGGIVLMLKGENALEVIEAVK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 311 ETMARLSKNFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLG 390
Cdd:COG3696 305 AKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 391 VSINTLSLFGLVLAIGIVVDDAIVVVENVERNIEK------GLSPLEATRVAMSEVTGPIIAIALVLSAVFIPTAFITGL 464
Cdd:COG3696 385 ISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEEnraagtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGV 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 465 SGQFYKQFALTITISTIISAFNSltlspalaalllkshdakpdaFTrlLNKLFGRWLFK--------PFNRVFNRgakGY 536
Cdd:COG3696 465 EGKLFRPMALTVIFALLGALLLS---------------------LT--LVPVLASLLLRgkvpekenPLVRWLKR---LY 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 537 EKLVQKLIRMTVVVMVAYIALVGGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHT 616
Cdd:COG3696 519 RPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESV 598
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 617 VAFPGlsvngftnSPNSGIVFTPLESFD-----KRTDPSQSAM---AIAAQLNKRFAAIDEAFVAVFPPppiqglgttgg 688
Cdd:COG3696 599 VSRTG--------RAEDATDPMGVNMSEtfvilKPRSEWRSGRtkeELIAEMREALEQIPGVNFNFSQP----------- 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 689 fklqIEDRANkgfEAL---------------FNSLQAvigKAQQDPALM----GLYSSFRIQV---PQMDIDIDREQALI 746
Cdd:COG3696 660 ----IQMRVD---ELLsgvradvavkifgddLDVLRR---LAEQIEAVLktvpGAADVQVERVtglPQLDIRIDRDAAAR 729
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 747 QGIPLDEVFNALQIYLG-----SVYVNDfnmfgRTYQVNAQADADYRLDPDQILNLKVRNRSGNMVPLGSVLTVTPTIGP 821
Cdd:COG3696 730 YGLNVADVQDVVETAIGgkavgQVYEGE-----RRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGP 804
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 822 DRVMHYNGYP----SAELNGSPAPGYSSD-QAQVAiEKVladTLPTGIEYEWT-EVTYQQVlAGNTMVYVFPLVVLLVFM 895
Cdd:COG3696 805 NQISRENGRRrivvQANVRGRDLGSFVAEaQAKVA-EQV---KLPPGYYIEWGgQFENLQR-ATARLAIVVPLALLLIFL 879
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 896 VLAAQYESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAILMVEFAKDRHDSGLSHLEAILEA 975
Cdd:COG3696 880 LLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEG 959
|
1050 1060 1070 1080 1090 1100 1110
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1889614193 976 CRMRLRPILMTSIAFTAGVVPLVLATGAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLVTNKKEKAQEN 1047
Cdd:COG3696 960 ALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
6-1046 |
6.01e-76 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 271.25 E-value: 6.01e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 6 FFIQRPIFAAMLSLVILIAGGISLFQLPVSEYPEVVPPTVVVTANYPGANPTVIAQTVATPLEQEI---NGTENMLYMFS 82
Cdd:TIGR00914 8 FSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMaglPGLETTRSLSR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 83 QGTSDgrmtLTVTFALGTDLDRAQVQVQNRVNSALPRLPEevqrlGVVAEKSsPDLTMV--VHLYSPE----------KT 150
Cdd:TIGR00914 88 YGLSQ----VTVIFKDGTDLYFARQLVNERLQQARDNLPE-----GVSPEMG-PISTGLgeIFLYTVEaeegarkkdgGA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 151 HDTAYLSNYADLNIKDEIARLPGVGDIRMFGAGKYSMRVWLNPDALAARELTATDVVTALRSQNQQVAAGSLgaqpisND 230
Cdd:TIGR00914 158 YTLTDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYI------ER 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 231 SQFQILLNVKGRLNSIEEFEQVIIKVGdEGQLTRLSDIARVDLGQDTYALRAELDNQPALAMPIFQRPGSNAIELSDQVR 310
Cdd:TIGR00914 232 RGEQYLVRAPGQVQSMDDIRNIVIATG-EGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVG 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 311 ETMARLSKNFPTGVEYDIVYDPTVFVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLG 390
Cdd:TIGR00914 311 DKLETINKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 391 VSINTLSLFGlvLAIGIVVDDAIVVVENVERNIEK-----GLSPLEATRV-----AMSEVTGPIIAIALVLSAVFIPTAF 460
Cdd:TIGR00914 391 ISANLMSLGA--LDFGLIVDGAVVIVENAHRRLAEaqhhhGRQLTLKERLhevfaASREVRRPLIFGQLIITLVFLPIFT 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 461 ITGLSGQFYKQFALTITISTIISAFNSLTLSPALAALLLKSHDAKPDaftrllnklfgrwlfkpfNRVFNRGAKGYEKLV 540
Cdd:TIGR00914 469 LTGVEGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKE------------------NRLMRVLKRRYEPLL 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 541 QKLIRMTVVVMVAYIALVGGTIKLFDTVPGGFIPQQDKQYLVAIAQLPDASSLDRTEDVLAQMQQIALEVPGVAHTVAFP 620
Cdd:TIGR00914 531 ERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKT 610
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 621 G-LSVNGFTNSPNSGIVFTPLESFDKRTDPSQSAMAIAAQLNKRFAAIDEAFVAVFPPPPIQGLGTTGGFKlqiEDRANK 699
Cdd:TIGR00914 611 GtAEIATDPMPPNASDTYIILKPESQWPEGKKTKEDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVR---SDVAVK 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 700 GFEALFNSL----QAVIGKAQQDPALMGLYSSFRIQVPQMDIDIDREQALIQGIPLDEVFNALQIYLGSVYVNDFNMFGR 775
Cdd:TIGR00914 688 VFGDDLDDLdataEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDR 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 776 TYQVNAQADADYRLDPDQILNL-----KVRNRSGNMVPLGSVLTVTPTIGPDRVMHYNGYP----SAELNGSPAPGYSSD 846
Cdd:TIGR00914 768 RFDIVIRLPESLRESPQALRQLpiplpLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRrvvvSANVRGRDLGSFVDD 847
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 847 QAQVAIEKVladTLPTGIEYEWTEvTYQQVLAGNT-MVYVFPLVVLLVFMVLAAQYESLRLPLAIILIVPMTIFSALLGV 925
Cdd:TIGR00914 848 AKKAIAEQV---KLPPGYWITWGG-QFEQLQSATKrLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFAL 923
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 926 WFVGSDNNIFTQIALIVLVALASKNAILMVEFAKDRHDSGLSHLEAILEACRMRLRPILMTSIAFTAGVVPLVLATGAGA 1005
Cdd:TIGR00914 924 WLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGA 1003
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|.
gi 1889614193 1006 EMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLVTNKKEKAQE 1046
Cdd:TIGR00914 1004 EVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRRHKGRK 1044
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
319-487 |
2.24e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.68 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 319 NFPTGVEYDIVYDPTV---FVRGSIDAVIATLLEAIVLVVIVVIVFLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINT 395
Cdd:TIGR00921 168 NPPSGKFLDVTGSPAInydIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYA 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 396 LSLFGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEvTGPIIAIALVLSAVFIPTAFITGLsgQFYKQFALT 475
Cdd:TIGR00921 248 TTLLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRR-TGRAVLIALLTTSAGFAALALSEF--PMVSEFGLG 324
|
170
....*....|..
gi 1889614193 476 ITISTIISAFNS 487
Cdd:TIGR00921 325 LVAGLITAYLLT 336
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
901-1049 |
2.49e-05 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 48.32 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 901 YESLRLPLAIILIVPMTIFSALLGVWFVGSDNNIFTQIALIVLVALASKNAI-LMVEFAKDRHDsGLSHLEAILEACRMR 979
Cdd:COG1033 239 FRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIhLLNRYREERRK-GLDKREALREALRKL 317
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 980 LRPILMTSIAFTAGVvpLVLATgAGAEMRHAMGNAVFSGMIGVTVFGLLFTPVFYMLVTNKKEKAQENTH 1049
Cdd:COG1033 318 GPPVLLTSLTTAIGF--LSLLF-SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKK 384
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
365-485 |
1.06e-04 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 46.39 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 365 WRASIIPLIAVPISLIGTFAVMQWLGVSINTLSLFGLVLAIGIVVDDAIVVVENVERNIEKGLSPLEATRVAMSEVTGPI 444
Cdd:COG1033 629 LRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAI 708
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1889614193 445 IAIALVLSAVFIPTAFItglSGQFYKQFALTITISTIISAF 485
Cdd:COG1033 709 LFTSLTLAAGFGVLLFS---SFPPLADFGLLLALGLLVALL 746
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
361-456 |
2.29e-04 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 45.24 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 361 FLQTWRASIIPLIAVPISLIGTFAVMQWLGVSINTLS--LFGLVLAIGivvddaivvvenV----------ERNIEKGLS 428
Cdd:COG1033 238 FFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG------------IdygihllnryREERRKGLD 305
|
90 100
....*....|....*....|....*...
gi 1889614193 429 PLEATRVAMSEVTGPIIAIALVLSAVFI 456
Cdd:COG1033 306 KREALREALRKLGPPVLLTSLTTAIGFL 333
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
903-1044 |
1.02e-03 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 43.31 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1889614193 903 SLRLPLaiILIVPMtIFSALL--GVW-FVGSDNNIFTQIALIVLVALASKNAILMVEFAKDRHDSGLSHLEAILEACRMR 979
Cdd:COG1033 628 SLRLGL--ISLIPN-LLPILLtfGLMgLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTT 704
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1889614193 980 LRPILMTSIAFTAGVVPLVLATGAG-AEMRHAMGNAVFSGMIGVtvfgLLFTPVFYMLVTNKKEKA 1044
Cdd:COG1033 705 GKAILFTSLTLAAGFGVLLFSSFPPlADFGLLLALGLLVALLAA----LLLLPALLLLLDPRIAKK 766
|
|
| |
