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Conserved domains on  [gi|1890134322|ref|WP_182971115|]
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MULTISPECIES: type IV secretion system protein TraC [Aeromonas]

Protein Classification

type IV secretion system protein TraC( domain architecture ID 11486812)

type IV secretion system protein TraC is one of the proteins encoded by the transfer (tra) region of the F pilus assembly Type-IV secretion system for plasmid transfer; is required for the assembly of mature F-pilin subunits into extended F pili

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13721 PRK13721
conjugal transfer ATP-binding protein TraC; Provisional
27-861 0e+00

conjugal transfer ATP-binding protein TraC; Provisional


:

Pssm-ID: 237480 [Multi-domain]  Cd Length: 844  Bit Score: 1543.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  27 ILGDLHYPQLSSMLPYRFYDADSGLYVNKSTVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQI 106
Cdd:PRK13721    1 VLGEMSFPQFSRLLPYRDYDQESGLFMNDTTMGFMLEAIPLNGANESIVEALDHMLRTKLPRGIPLCIHLMSSKLVGDRI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 107 DHGIAQFSWQGKHAERFNRITRAFYHSAAHGRFGSPT--NLPLTLRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASL 184
Cdd:PRK13721   81 EYGLREFSWSGEQAERFNAITRAYYMRAALTQFPLPEgmNLPLTLRHYRVFISYCSPSKKKSRADILEMENLVKIIRASL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 185 ESAKIATAQVDQTAFVNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLLLTLdAGDGQKSRARIMNF 264
Cdd:PRK13721  161 QGASITTQTVDAQAFISIVREMINHRPDSLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGL-RENGRNSTARILNF 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 265 MLEQNPDLFMLWQGGDNISNLLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWG 344
Cdd:PRK13721  240 HLAKNPEIAFLWQMADNYSNLLNPELSISCPFILTLTLEVEDQVKTQSEANLKYMDLEKKSKTSYAKWFPSVEKEAKEWG 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 345 SLRENLNSNSSCLVRYFFNLTAFCPDDEEAALICEQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEGLWDDLKASG 424
Cdd:PRK13721  320 ELRQRLGSNQSSLVSYFLNITAFCPDNNETALEVEQDILNSFRKNGFELISPRFNHMRNFLTCLPFMAGEGLFKDLKEAG 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 425 ATSRAESTQAVNLLPLVADNRLCQSGLLAPSYRNQLAFLDIFDTGLGNTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGS 504
Cdd:PRK13721  400 VVQRAESFNVANLMPLVADNPLTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGGF 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 505 VWVFDMGDGYKSFCENVGGTYLDGQNLKFNPFANITNIHASGERIRDQLSVLASPNGKLDEVHEDLLLRGILNAWKDKQQ 584
Cdd:PRK13721  480 AVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERIRDQLSVMASPNGNLDEVHEGLLLQAVRASWLAKKN 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 585 KARIDDVVAFLKTERDLDHYANSASITSRMDEIIELLGKYCSTGIYGEFFNSDSPSLTDDANMVVLELGGLQDKPSLLVA 664
Cdd:PRK13721  560 RARIDDVVDFLKNARDSEQYADSPTIRSRLDEMIVLLDQYTANGTYGEYFNSDEPSLRDDARMVVLELGGLEDRPSLLVA 639
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 665 VMFSLIIYIEDKMYRSDRSLKKVCCIDEGWKLLNFKNDKVGSFIETGYRTVRRHTGSFITISQNIKDFDADDASSAAKAA 744
Cdd:PRK13721  640 VMFSLIIYIENRMYRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSDKASSAARAA 719
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 745 WGNSAFKVVLKQDASEFKIYNQNRPNQFSELERLAISRFGDAKDQWFSSFMLRINDTSSFHRLFVDPLSRAMFSSNGKDF 824
Cdd:PRK13721  720 WGNSSYKIILKQSAKEFAKYNQLYPDQFSPLERDMIGGFGAAKDQWFSSFLLQVENHSSWHRLFVDPLSRAMYSSDGPDF 799
                         810       820       830
                  ....*....|....*....|....*....|....*..
gi 1890134322 825 EFLQQRRAEGVDIHDAVYELALLRFPDEMEALASWHH 861
Cdd:PRK13721  800 EFVQQKRKEGLSIHEAVWQLAWKKFGPEMASLEAWLE 836
 
Name Accession Description Interval E-value
PRK13721 PRK13721
conjugal transfer ATP-binding protein TraC; Provisional
27-861 0e+00

conjugal transfer ATP-binding protein TraC; Provisional


Pssm-ID: 237480 [Multi-domain]  Cd Length: 844  Bit Score: 1543.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  27 ILGDLHYPQLSSMLPYRFYDADSGLYVNKSTVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQI 106
Cdd:PRK13721    1 VLGEMSFPQFSRLLPYRDYDQESGLFMNDTTMGFMLEAIPLNGANESIVEALDHMLRTKLPRGIPLCIHLMSSKLVGDRI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 107 DHGIAQFSWQGKHAERFNRITRAFYHSAAHGRFGSPT--NLPLTLRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASL 184
Cdd:PRK13721   81 EYGLREFSWSGEQAERFNAITRAYYMRAALTQFPLPEgmNLPLTLRHYRVFISYCSPSKKKSRADILEMENLVKIIRASL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 185 ESAKIATAQVDQTAFVNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLLLTLdAGDGQKSRARIMNF 264
Cdd:PRK13721  161 QGASITTQTVDAQAFISIVREMINHRPDSLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGL-RENGRNSTARILNF 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 265 MLEQNPDLFMLWQGGDNISNLLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWG 344
Cdd:PRK13721  240 HLAKNPEIAFLWQMADNYSNLLNPELSISCPFILTLTLEVEDQVKTQSEANLKYMDLEKKSKTSYAKWFPSVEKEAKEWG 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 345 SLRENLNSNSSCLVRYFFNLTAFCPDDEEAALICEQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEGLWDDLKASG 424
Cdd:PRK13721  320 ELRQRLGSNQSSLVSYFLNITAFCPDNNETALEVEQDILNSFRKNGFELISPRFNHMRNFLTCLPFMAGEGLFKDLKEAG 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 425 ATSRAESTQAVNLLPLVADNRLCQSGLLAPSYRNQLAFLDIFDTGLGNTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGS 504
Cdd:PRK13721  400 VVQRAESFNVANLMPLVADNPLTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGGF 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 505 VWVFDMGDGYKSFCENVGGTYLDGQNLKFNPFANITNIHASGERIRDQLSVLASPNGKLDEVHEDLLLRGILNAWKDKQQ 584
Cdd:PRK13721  480 AVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERIRDQLSVMASPNGNLDEVHEGLLLQAVRASWLAKKN 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 585 KARIDDVVAFLKTERDLDHYANSASITSRMDEIIELLGKYCSTGIYGEFFNSDSPSLTDDANMVVLELGGLQDKPSLLVA 664
Cdd:PRK13721  560 RARIDDVVDFLKNARDSEQYADSPTIRSRLDEMIVLLDQYTANGTYGEYFNSDEPSLRDDARMVVLELGGLEDRPSLLVA 639
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 665 VMFSLIIYIEDKMYRSDRSLKKVCCIDEGWKLLNFKNDKVGSFIETGYRTVRRHTGSFITISQNIKDFDADDASSAAKAA 744
Cdd:PRK13721  640 VMFSLIIYIENRMYRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSDKASSAARAA 719
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 745 WGNSAFKVVLKQDASEFKIYNQNRPNQFSELERLAISRFGDAKDQWFSSFMLRINDTSSFHRLFVDPLSRAMFSSNGKDF 824
Cdd:PRK13721  720 WGNSSYKIILKQSAKEFAKYNQLYPDQFSPLERDMIGGFGAAKDQWFSSFLLQVENHSSWHRLFVDPLSRAMYSSDGPDF 799
                         810       820       830
                  ....*....|....*....|....*....|....*..
gi 1890134322 825 EFLQQRRAEGVDIHDAVYELALLRFPDEMEALASWHH 861
Cdd:PRK13721  800 EFVQQKRKEGLSIHEAVWQLAWKKFGPEMASLEAWLE 836
TraC-F-type TIGR02746
type-IV secretion system protein TraC; The protein family described here is common among the F, ...
40-846 0e+00

type-IV secretion system protein TraC; The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.


Pssm-ID: 274279 [Multi-domain]  Cd Length: 797  Bit Score: 762.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  40 LPYRFYDADSGLYVNKSTVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQIDHGIAQFSWQGKH 119
Cdd:TIGR02746   2 LPYRAYDEESGIFMNRHSMGFGLELTPLSGADESLVESLSSLLRTDLPEGTDIQVLLWGSPQIGPFLDRNEEQFSQNGGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 120 AERFNRITRAFYHSAAHGRFGspTNLPLTLRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASLESAKIATAQVDQTAF 199
Cdd:TIGR02746  82 LEKLARNRVKYYLNAAQKGFF--KNSGVTLRDFRLFLSVSIPFKSPNEDVIQELRSLRERIESTLRSAGFGCRRVDAEDL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 200 VNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLllTLDAGDGQK-SRARIMNFMLEQNPDLFMLWQG 278
Cdd:TIGR02746 160 LSLVREMLNPDPDSIHPWPISYDPNQLLRDQIVDPDTDLEVHEGGL--EVDHEDNQGeVKTRIRVFSIKRFPEEFTLWQT 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 279 GDNISNLLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWGSLRENLNSNSSCLV 358
Cdd:TIGR02746 238 GNLIGDLLNPSLQITCPFLLSFTVRVEDQVKKKAKATAKAKDLNKQAKSSMAKWVPSLEKKLKEIKYLREAIASGGDSLV 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 359 RYFFNLTAFCPDDEEAALicEQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEGLWDDLKASGATSRAESTQAVNLL 438
Cdd:TIGR02746 318 SMYYNVLLFTNPDNLRRD--VEAAKSSFRKNGFDLAEDKRIQLQAFLAALPFNPTEGLFEDLKKAGRVRTLSSANAVNLL 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 439 PLVADNRLC-QSGLLAPSYRNQLAFLDIFDTGLgnTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGSVWVFDMGDGYKSF 517
Cdd:TIGR02746 396 PLIADWKGTkGSGLLLPTRRGQLSAFDPFDSDS--TNYNIAVVGGSGAGKSFFMQELIVDNLSRGGKVWVIDVGRSYKKL 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 518 CENVGGTYLDG---QNLKFNPFA--NITNIHASGERIRDQLSVLASPNGKLDEVHEDLLLRGILNAWKDKQQKARIDDVV 592
Cdd:TIGR02746 474 CEMLGGTYIEFspeSNICLNPFTgnNVTEIDDEIDQITALIALMASPEGGLSDEQRSTLEEAILAAWKEYGNEATITDVQ 553
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 593 AFLKTERDLDHYansasitSRMDEIIELLGKYCSTGIYGEFFNSDSpSLTDDANMVVLELGGLQDKPSLLVAVMFSLIIY 672
Cdd:TIGR02746 554 DALQQLEDDEND-------PRIKDLGKMLNPYTSHGVYGRYFNGPN-NLDFSNRFVVLELEELEDRPDLQAVVLFSLMVR 625
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 673 IEDKMYRSDRSLKKVCCIDEGWKLLNFKNDKVGSFIETGYRTVRRHTGSFITISQNIkdfDADDASSAAKAAWGNSAFKV 752
Cdd:TIGR02746 626 ITGEMYLTPRKRRKICIIDEAWSLLDGANPQAADFIETGYRRARKYGGAFITITQGI---EDFYSSPEARAAYANSDWKI 702
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 753 VLKQDASEFKIYNQNRPNQFSELERLAISRFGDAKDQwFSSFMLRINDTSSFHRLFVDPLSRAMFSSNGKDFEFLQQRRA 832
Cdd:TIGR02746 703 ILRQSAESIAKLKAENPFTFSPFEKRLIKSLRTAKGA-FSELLIRSGEGSSVHRLFVDPFSRVLFSTDGPEFEEVEELRE 781
                         810
                  ....*....|....
gi 1890134322 833 EGVDIHDAVYELAL 846
Cdd:TIGR02746 782 QGLSLEEAIEQLAQ 795
VirB4 COG3451
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ...
285-834 6.48e-99

Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442674 [Multi-domain]  Cd Length: 546  Bit Score: 318.81  E-value: 6.48e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 285 LLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWGSLRENLNSNSSCLVRYFFNL 364
Cdd:COG3451    26 LLDPLLQLPCEFIVTQSFTPLDKDEALKKLKRKRRRLESKRKSEQALVDDDAESQAEDAEEALDELQSGGERLGEVHLTL 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 365 TAFCPDDEEAALICeQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEglwdDLKASGATSRAestqAVNLLPLVADN 444
Cdd:COG3451   106 TVFADDLEELEEAV-REVESALQSAGFTLVRETLNQEEAFLSSLPGNFDY----RLRRRLLTTSN----LAALFPFHSFE 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 445 RLCQSGL-LAPSYRNQLAFLDIFDtglGNTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGSVWVFDMGDGYKSFCENVGG 523
Cdd:COG3451   177 LGDPWGIyLLNTRSGTPVFFDFHD---GLDNGNTLILGPSGSGKSFLLKLLLLQLLRYGARIVIFDPGGSYEILVRALGG 253
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 524 TYLD---GQNLKFNPFAnITNIHASGERIRDQLSVLASPNGK-LDEVHEDLLLRGILNAWKDKQQKAR--IDDVVAFLKT 597
Cdd:COG3451   254 TYIDlspGSPTGLNPFD-LEDTEEKRDFLLELLELLLGREGEpLTPEERAAIDRAVRALYRRADPEERttLSDLYELLKE 332
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 598 ERDLDhyansasitsrmdEIIELLGKYCSTGIYGEFFNSDSPSLTDDANMVVLELGGLQDKPSLLVAVMFSLIIYIEDKM 677
Cdd:COG3451   333 QPEAK-------------DLAARLEPYTKGGSYGWLFDGPTNLDLSDARFVVFDLTELLDNPELRPPVLLYLLHRIWNRL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 678 YRSDRSLKKVCCIDEGWKLLnfKNDKVGSFIETGYRTVRRHTGSFITISQNIKdfdADDASSAAKAAWGNSAFKVVLKQD 757
Cdd:COG3451   400 RKNNDGRPTLIVIDEAWLLL--DNPAFAEFLEEWLKTLRKYNGAVIFATQSVE---DFLSSPIAEAIIENSATKILLPQP 474
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1890134322 758 ASEFKIYNQNRpnQFSELERLAISRFGDAKDQwfssFMLRINDTSSFHRLFVDPLSRAMFSSNGKDFEFLQQRRAEG 834
Cdd:COG3451   475 KADIEDYAELL--GLSERELELIRSAGRGKRD----FLIKQGNGSVVFRLDLSPEELALLSTKPEEVAILDELRAEH 545
TraC_F_IV pfam11130
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a ...
34-271 1.13e-42

TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process.


Pssm-ID: 431669 [Multi-domain]  Cd Length: 232  Bit Score: 155.13  E-value: 1.13e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  34 PQLSSMLPYRFYDADSGLYVNK-STVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQIDHGIAQ 112
Cdd:pfam11130   1 PSFSDLLPYVAYDPETGLFLNEdGSVGFVFELSPLGGADESVRDTLESLLSDDLPDGTPVQFLLFASPDIGPYLDRLRDY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 113 -FSWQGKHAERFNRITRAFYHSAAHGRFGSPTNLPLtlRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASLESAKIAT 191
Cdd:pfam11130  81 rLGEQGGHLRAIARPRGLFLDSGVTGSLSADWRGQL--RRFRLVLSRKVPGKADLPTPIEALNELRDRLEASLRSAGLAA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 192 AQVDQTAFVNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLLLtldagDGQKSRaRIMNFMLEQNPD 271
Cdd:pfam11130 159 RRLDPDDLIAWLRRWLNPDPSASWDPPADYDPDKDIAEQILDSDPRLDVEAGRLYF-----DGEPHR-AVRVLSLRRFPE 232
 
Name Accession Description Interval E-value
PRK13721 PRK13721
conjugal transfer ATP-binding protein TraC; Provisional
27-861 0e+00

conjugal transfer ATP-binding protein TraC; Provisional


Pssm-ID: 237480 [Multi-domain]  Cd Length: 844  Bit Score: 1543.52  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  27 ILGDLHYPQLSSMLPYRFYDADSGLYVNKSTVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQI 106
Cdd:PRK13721    1 VLGEMSFPQFSRLLPYRDYDQESGLFMNDTTMGFMLEAIPLNGANESIVEALDHMLRTKLPRGIPLCIHLMSSKLVGDRI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 107 DHGIAQFSWQGKHAERFNRITRAFYHSAAHGRFGSPT--NLPLTLRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASL 184
Cdd:PRK13721   81 EYGLREFSWSGEQAERFNAITRAYYMRAALTQFPLPEgmNLPLTLRHYRVFISYCSPSKKKSRADILEMENLVKIIRASL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 185 ESAKIATAQVDQTAFVNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLLLTLdAGDGQKSRARIMNF 264
Cdd:PRK13721  161 QGASITTQTVDAQAFISIVREMINHRPDSLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGL-RENGRNSTARILNF 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 265 MLEQNPDLFMLWQGGDNISNLLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWG 344
Cdd:PRK13721  240 HLAKNPEIAFLWQMADNYSNLLNPELSISCPFILTLTLEVEDQVKTQSEANLKYMDLEKKSKTSYAKWFPSVEKEAKEWG 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 345 SLRENLNSNSSCLVRYFFNLTAFCPDDEEAALICEQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEGLWDDLKASG 424
Cdd:PRK13721  320 ELRQRLGSNQSSLVSYFLNITAFCPDNNETALEVEQDILNSFRKNGFELISPRFNHMRNFLTCLPFMAGEGLFKDLKEAG 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 425 ATSRAESTQAVNLLPLVADNRLCQSGLLAPSYRNQLAFLDIFDTGLGNTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGS 504
Cdd:PRK13721  400 VVQRAESFNVANLMPLVADNPLTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGGF 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 505 VWVFDMGDGYKSFCENVGGTYLDGQNLKFNPFANITNIHASGERIRDQLSVLASPNGKLDEVHEDLLLRGILNAWKDKQQ 584
Cdd:PRK13721  480 AVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERIRDQLSVMASPNGNLDEVHEGLLLQAVRASWLAKKN 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 585 KARIDDVVAFLKTERDLDHYANSASITSRMDEIIELLGKYCSTGIYGEFFNSDSPSLTDDANMVVLELGGLQDKPSLLVA 664
Cdd:PRK13721  560 RARIDDVVDFLKNARDSEQYADSPTIRSRLDEMIVLLDQYTANGTYGEYFNSDEPSLRDDARMVVLELGGLEDRPSLLVA 639
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 665 VMFSLIIYIEDKMYRSDRSLKKVCCIDEGWKLLNFKNDKVGSFIETGYRTVRRHTGSFITISQNIKDFDADDASSAAKAA 744
Cdd:PRK13721  640 VMFSLIIYIENRMYRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSDKASSAARAA 719
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 745 WGNSAFKVVLKQDASEFKIYNQNRPNQFSELERLAISRFGDAKDQWFSSFMLRINDTSSFHRLFVDPLSRAMFSSNGKDF 824
Cdd:PRK13721  720 WGNSSYKIILKQSAKEFAKYNQLYPDQFSPLERDMIGGFGAAKDQWFSSFLLQVENHSSWHRLFVDPLSRAMYSSDGPDF 799
                         810       820       830
                  ....*....|....*....|....*....|....*..
gi 1890134322 825 EFLQQRRAEGVDIHDAVYELALLRFPDEMEALASWHH 861
Cdd:PRK13721  800 EFVQQKRKEGLSIHEAVWQLAWKKFGPEMASLEAWLE 836
TraC-F-type TIGR02746
type-IV secretion system protein TraC; The protein family described here is common among the F, ...
40-846 0e+00

type-IV secretion system protein TraC; The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.


Pssm-ID: 274279 [Multi-domain]  Cd Length: 797  Bit Score: 762.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  40 LPYRFYDADSGLYVNKSTVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQIDHGIAQFSWQGKH 119
Cdd:TIGR02746   2 LPYRAYDEESGIFMNRHSMGFGLELTPLSGADESLVESLSSLLRTDLPEGTDIQVLLWGSPQIGPFLDRNEEQFSQNGGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 120 AERFNRITRAFYHSAAHGRFGspTNLPLTLRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASLESAKIATAQVDQTAF 199
Cdd:TIGR02746  82 LEKLARNRVKYYLNAAQKGFF--KNSGVTLRDFRLFLSVSIPFKSPNEDVIQELRSLRERIESTLRSAGFGCRRVDAEDL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 200 VNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLllTLDAGDGQK-SRARIMNFMLEQNPDLFMLWQG 278
Cdd:TIGR02746 160 LSLVREMLNPDPDSIHPWPISYDPNQLLRDQIVDPDTDLEVHEGGL--EVDHEDNQGeVKTRIRVFSIKRFPEEFTLWQT 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 279 GDNISNLLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWGSLRENLNSNSSCLV 358
Cdd:TIGR02746 238 GNLIGDLLNPSLQITCPFLLSFTVRVEDQVKKKAKATAKAKDLNKQAKSSMAKWVPSLEKKLKEIKYLREAIASGGDSLV 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 359 RYFFNLTAFCPDDEEAALicEQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEGLWDDLKASGATSRAESTQAVNLL 438
Cdd:TIGR02746 318 SMYYNVLLFTNPDNLRRD--VEAAKSSFRKNGFDLAEDKRIQLQAFLAALPFNPTEGLFEDLKKAGRVRTLSSANAVNLL 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 439 PLVADNRLC-QSGLLAPSYRNQLAFLDIFDTGLgnTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGSVWVFDMGDGYKSF 517
Cdd:TIGR02746 396 PLIADWKGTkGSGLLLPTRRGQLSAFDPFDSDS--TNYNIAVVGGSGAGKSFFMQELIVDNLSRGGKVWVIDVGRSYKKL 473
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 518 CENVGGTYLDG---QNLKFNPFA--NITNIHASGERIRDQLSVLASPNGKLDEVHEDLLLRGILNAWKDKQQKARIDDVV 592
Cdd:TIGR02746 474 CEMLGGTYIEFspeSNICLNPFTgnNVTEIDDEIDQITALIALMASPEGGLSDEQRSTLEEAILAAWKEYGNEATITDVQ 553
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 593 AFLKTERDLDHYansasitSRMDEIIELLGKYCSTGIYGEFFNSDSpSLTDDANMVVLELGGLQDKPSLLVAVMFSLIIY 672
Cdd:TIGR02746 554 DALQQLEDDEND-------PRIKDLGKMLNPYTSHGVYGRYFNGPN-NLDFSNRFVVLELEELEDRPDLQAVVLFSLMVR 625
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 673 IEDKMYRSDRSLKKVCCIDEGWKLLNFKNDKVGSFIETGYRTVRRHTGSFITISQNIkdfDADDASSAAKAAWGNSAFKV 752
Cdd:TIGR02746 626 ITGEMYLTPRKRRKICIIDEAWSLLDGANPQAADFIETGYRRARKYGGAFITITQGI---EDFYSSPEARAAYANSDWKI 702
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 753 VLKQDASEFKIYNQNRPNQFSELERLAISRFGDAKDQwFSSFMLRINDTSSFHRLFVDPLSRAMFSSNGKDFEFLQQRRA 832
Cdd:TIGR02746 703 ILRQSAESIAKLKAENPFTFSPFEKRLIKSLRTAKGA-FSELLIRSGEGSSVHRLFVDPFSRVLFSTDGPEFEEVEELRE 781
                         810
                  ....*....|....
gi 1890134322 833 EGVDIHDAVYELAL 846
Cdd:TIGR02746 782 QGLSLEEAIEQLAQ 795
VirB4 COG3451
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ...
285-834 6.48e-99

Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442674 [Multi-domain]  Cd Length: 546  Bit Score: 318.81  E-value: 6.48e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 285 LLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWGSLRENLNSNSSCLVRYFFNL 364
Cdd:COG3451    26 LLDPLLQLPCEFIVTQSFTPLDKDEALKKLKRKRRRLESKRKSEQALVDDDAESQAEDAEEALDELQSGGERLGEVHLTL 105
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 365 TAFCPDDEEAALICeQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEglwdDLKASGATSRAestqAVNLLPLVADN 444
Cdd:COG3451   106 TVFADDLEELEEAV-REVESALQSAGFTLVRETLNQEEAFLSSLPGNFDY----RLRRRLLTTSN----LAALFPFHSFE 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 445 RLCQSGL-LAPSYRNQLAFLDIFDtglGNTNYNMAVSGTSGAGKTGLVQPILRSVLDSGGSVWVFDMGDGYKSFCENVGG 523
Cdd:COG3451   177 LGDPWGIyLLNTRSGTPVFFDFHD---GLDNGNTLILGPSGSGKSFLLKLLLLQLLRYGARIVIFDPGGSYEILVRALGG 253
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 524 TYLD---GQNLKFNPFAnITNIHASGERIRDQLSVLASPNGK-LDEVHEDLLLRGILNAWKDKQQKAR--IDDVVAFLKT 597
Cdd:COG3451   254 TYIDlspGSPTGLNPFD-LEDTEEKRDFLLELLELLLGREGEpLTPEERAAIDRAVRALYRRADPEERttLSDLYELLKE 332
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 598 ERDLDhyansasitsrmdEIIELLGKYCSTGIYGEFFNSDSPSLTDDANMVVLELGGLQDKPSLLVAVMFSLIIYIEDKM 677
Cdd:COG3451   333 QPEAK-------------DLAARLEPYTKGGSYGWLFDGPTNLDLSDARFVVFDLTELLDNPELRPPVLLYLLHRIWNRL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 678 YRSDRSLKKVCCIDEGWKLLnfKNDKVGSFIETGYRTVRRHTGSFITISQNIKdfdADDASSAAKAAWGNSAFKVVLKQD 757
Cdd:COG3451   400 RKNNDGRPTLIVIDEAWLLL--DNPAFAEFLEEWLKTLRKYNGAVIFATQSVE---DFLSSPIAEAIIENSATKILLPQP 474
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1890134322 758 ASEFKIYNQNRpnQFSELERLAISRFGDAKDQwfssFMLRINDTSSFHRLFVDPLSRAMFSSNGKDFEFLQQRRAEG 834
Cdd:COG3451   475 KADIEDYAELL--GLSERELELIRSAGRGKRD----FLIKQGNGSVVFRLDLSPEELALLSTKPEEVAILDELRAEH 545
TraC_F_IV pfam11130
TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a ...
34-271 1.13e-42

TraC protein; This family of TraC proteins is conserved in Proteobacteria. TraC is a cytoplasmic, peripheral membrane protein and is one of the proteins encoded by the F transfer region of the conjugative plasmid that is required for the assembly of F pilin into the mature F pilus structure. F pili are filamentous appendages that help establish the physical contact between donor and recipient cells involved in the conjugation process.


Pssm-ID: 431669 [Multi-domain]  Cd Length: 232  Bit Score: 155.13  E-value: 1.13e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322  34 PQLSSMLPYRFYDADSGLYVNK-STVGFMLEATPLIGANEHIVQVLDDLVKSKLPRKVPISVHLVSTKVIGDQIDHGIAQ 112
Cdd:pfam11130   1 PSFSDLLPYVAYDPETGLFLNEdGSVGFVFELSPLGGADESVRDTLESLLSDDLPDGTPVQFLLFASPDIGPYLDRLRDY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 113 -FSWQGKHAERFNRITRAFYHSAAHGRFGSPTNLPLtlRDYRVYISYCAKAKKLDKTAITELSHLLKIVRASLESAKIAT 191
Cdd:pfam11130  81 rLGEQGGHLRAIARPRGLFLDSGVTGSLSADWRGQL--RRFRLVLSRKVPGKADLPTPIEALNELRDRLEASLRSAGLAA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 192 AQVDQTAFVNIINQMANHRPEQIIATPKNLQQYDELNFQCLDRSTSLEVKPDYLLLtldagDGQKSRaRIMNFMLEQNPD 271
Cdd:pfam11130 159 RRLDPDDLIAWLRRWLNPDPSASWDPPADYDPDKDIAEQILDSDPRLDVEAGRLYF-----DGEPHR-AVRVLSLRRFPE 232
DUF5934 pfam19357
Family of unknown function (DUF5934); This presumed domain found in type IV secretion system ...
282-440 1.04e-12

Family of unknown function (DUF5934); This presumed domain found in type IV secretion system proteins is functionally uncharacterized. This domain family is found in proteobacteria, and is approximately 170 amino acids in length. The family is found in association with pfam11130. There are two conserved sequence motifs: GWDL and QGEY.


Pssm-ID: 437189 [Multi-domain]  Cd Length: 172  Bit Score: 67.04  E-value: 1.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 282 ISNLLSPDLCVASPFVLTMTLEAEEQVSTQNEATRKFFDLDKKANSPYGKLFPGVGKQAQEWGSLRENLNSNSScLVRYF 361
Cdd:pfam19357   1 IGDMFNDKLRLPCPVATSLCLVYPDQEAASSKAGYKFMRTTSLADSKSARFLPQLKEQSAEWQHVQDELRQGRK-LVRAF 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1890134322 362 FNLTAFCPDDEEAAliCEQQVINTFKKNGLHLYSPVFMQMRNYLAMFPFCAGEGLWDDLKASGATSRAESTQAVNLLPL 440
Cdd:pfam19357  80 YSVTAFSPKGKGDA--HERTLKSVYKAAGWDLIDERYLQIMGLLAAMPLTLADGLASDLERMKRFRTMLTTTAANIAPL 156
HerA COG0433
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase ...
473-698 1.34e-11

Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains [Replication, recombination and repair];


Pssm-ID: 440202 [Multi-domain]  Cd Length: 388  Bit Score: 67.32  E-value: 1.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 473 TNYNMAVSGTSGAGKTGLVQPILRSVLDSGGSVWVFDMGDGYKSFCENVGG-------TYLDGQNLKFNPFanitNIHAS 545
Cdd:COG0433    46 LNRHILILGATGSGKSNTLQVLLEELSRAGVPVLVFDPHGEYSGLAEPGAEradvgvfDPGAGRPLPINPW----DLFAT 121
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 546 GERIRDqlsvLASPNGKLDEVHEDLLLRGILNAWKDKQQKARIDDVVAFLKTERDLDHYANSAS------ITSRMDEIIE 619
Cdd:COG0433   122 ASELGP----LLLSRLDLNDTQRGVLREALRLADDKGLLLLDLKDLIALLEEGEELGEEYGNVSaasagaLLRRLESLES 197
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 620 LlgkycstgiyGEFFNSDSPSLTD----DANMVVLELGGLQDKpsLLVAVMFSLIIYIEDKMYRSDRSLKK----VCCID 691
Cdd:COG0433   198 A----------DGLFGEPGLDLEDllrtDGRVTVIDLSGLPEE--LQSTFVLWLLRELFEARPEVGDADDRklplVLVID 265

                  ....*..
gi 1890134322 692 EGWKLLN 698
Cdd:COG0433   266 EAHLLAP 272
P-loop_TraG pfam19044
TraG P-loop domain; This entry represents the P-loop domain found in the TraG conjugation ...
462-729 6.11e-11

TraG P-loop domain; This entry represents the P-loop domain found in the TraG conjugation protein.


Pssm-ID: 436917 [Multi-domain]  Cd Length: 413  Bit Score: 65.23  E-value: 6.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 462 FLDIFDTGLGN---TNYNMAVSGTSGAGKTGLVQPILRSVLDSGGSVWVFDMGDGYKSFCENVGG---TYLDGQNLKFNP 535
Cdd:pfam19044  14 HVDISDEPMKKgiiTNRNKFILGPSGSGKSFFTNHMVRSYYEQGAHVVLVDVGHSYKGLCELVGGyyfTYSEENPIRFNP 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 536 FanitnihasgerirdqlsvLASPNGKLDEVHEDLLLRGILNAWKDKQQKARIDDVVA---------------------- 593
Cdd:pfam19044  94 F-------------------YIGDGDVLDTEKKESIKTLLLALWKKDDESFTRSEYVAlsnaltlyyehlekdpdifpcf 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 594 -----FLKT------------ERDLDhyansasitsrMDEIIELLGKYCSTGIYGEFFNSdspsltdDANM-------VV 649
Cdd:pfam19044 155 ntfyeFLRDeylkvleedkvkEKDFD-----------IDNFLYVLRPYYKGGEFDYLLNA-------TENLdllnerfIV 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 650 LELGGLQDKPSLLVAVmfSLII---YIeDKMyrsdRSLK---KVCCIDEGWKLLnfKNDKVGSFIETGYRTVRRHTGSFI 723
Cdd:pfam19044 217 FELDNIKDHPILFPVV--TIIImevFI-SKM----RKLKgirKMILIEEAWKAI--AKEGMAEYIKYLFKTVRKFFGEAI 287

                  ....*.
gi 1890134322 724 TISQNI 729
Cdd:pfam19044 288 VVTQEV 293
DUF87 pfam01935
Helicase HerA, central domain; This entry represents the central domain found in archaeal ...
477-623 3.12e-03

Helicase HerA, central domain; This entry represents the central domain found in archaeal proteins such as DNA double-strand break repair helicase HerA (EC:3.6.4.12). HerA is a helicase which is able to utilize either 3' or 5' single-stranded DNA extensions for loading and subsequent DNA duplex unwinding. It forms a complex with NurA nuclease, this complex has the 5'-3' DNA end resection activity and is essential for cell viability in the crenarchaeon Sulfolobus islandicus. This domain includes the the central RecA-like catalytic core and a flanking four-helix bundle. The function of this prokaryotic domain is unknown. It contains several conserved aspartates and histidines that could be metal ligands.


Pssm-ID: 376671 [Multi-domain]  Cd Length: 220  Bit Score: 40.04  E-value: 3.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1890134322 477 MAVSGTSGAGKTGLVQPILRSVLDS-GGSVWVFDM-GDGYKSFCENVGGTYldgqnLKFNPFANITnIHASGERIRDQLS 554
Cdd:pfam01935  26 FAILGSTGSGKSNTVAVLLEELLEKkGATVLIFDPhGEYGTLFRDLGAENV-----NVITPDPELK-INPWLLSPEDLAD 99
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1890134322 555 VLASPNGKLDEVHEDLLLRGILNAWKDKQQKARIDDVVAFLktERDLDHYANSASiTSRMDEIIELLGK 623
Cdd:pfam01935 100 LLEELNLPNAEVQRSILEEALDQLKSEELGKLSIDELIEKI--LEELLTEAAELN-KLSNDAIRRVLDK 165
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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