|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
3-1042 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 1374.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 3 PSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTS 82
Cdd:PRK10503 12 PSRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 83 SSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVENRL 162
Cdd:PRK10503 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 163 APKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQ 242
Cdd:PRK10503 172 AQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYR 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 243 NLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILAD 322
Cdd:PRK10503 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSD 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 323 RTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDD 402
Cdd:PRK10503 332 RTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDD 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 403 AIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLT 482
Cdd:PRK10503 412 AIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLT 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 483 PMMSARLLRPETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGLVQ 562
Cdd:PRK10503 492 PMMCARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQ 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 563 VITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGANASLNTGRMQITLKPFAQRHASATEVIARLGDLNRQV 642
Cdd:PRK10503 572 GTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAKV 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 643 PGITAYMQPVQDLTIEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGRLG 722
Cdd:PRK10503 652 PGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLG 731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 723 VTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTTsatgtaatttvqVPLSSVAQIV 802
Cdd:PRK10503 732 ISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGV------------VPLSSIATIE 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 803 ERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTMYI 882
Cdd:PRK10503 800 QRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYI 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 883 VLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQGLDPRAAIHQ 962
Cdd:PRK10503 880 VLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQ 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 963 ASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFARMAQRWRERRGVKRET 1042
Cdd:PRK10503 960 ACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHEEE 1039
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1027 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1200.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 4 SRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSS 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 84 SSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVENRLA 163
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 164 PKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQN 243
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 244 LIIAWK-NGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILAD 322
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 323 RTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDD 402
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 403 AIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLT 482
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 483 PMMSARLLRpeTEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGLVQ 562
Cdd:NF033617 481 PMMCSRLLK--ANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIF 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 563 VITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGaNASLNTGRMQITLKPFAQRHASATEVIARLGDLNRQV 642
Cdd:NF033617 559 GMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGG-NPGDNTGFGIINLKPWDERDVSAQEIIDRLRPKLAKV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 643 PGITAYMQPVQDLTIEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGRLG 722
Cdd:NF033617 638 PGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 723 VTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTtsatgtaatttvQVPLSSVAQIV 802
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGK------------LVPLSTLAKIE 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 803 ERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKaEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTMYI 882
Cdd:NF033617 786 ERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALD-QAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYL 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 883 VLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQGLDPRAAIHQ 962
Cdd:NF033617 865 VLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQ 944
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1891041650 963 ASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFAR 1027
Cdd:NF033617 945 AAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1032 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1088.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 1 MNPSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 81 TSSSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLpMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVEN 160
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 161 RLAPKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAE 240
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 241 YQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQIL 320
Cdd:COG0841 240 FENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 321 ADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVV 400
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 401 DDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLT 480
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 481 LTPMMSARLLRPETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGL 560
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 561 VQVITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGANASLNTGRMQITLKPFAQRHASATEVIARLGDLNR 640
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 641 QVPGITAYMQPVQDltiEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGR 720
Cdd:COG0841 640 KIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAA 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 721 LGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTtsatgtaatttvQVPLSSVAQ 800
Cdd:COG0841 717 LGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGE------------MVPLSSVAT 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 801 IVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTM 880
Cdd:COG0841 785 IEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLV 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 881 YIVLGVLYESYIHPVTILSTLPSA---------------------------GVgallalliggldlgiiaiigivlligi 933
Cdd:COG0841 865 YLVLAAQFESFIQPLIILLTVPLAligallgllltgtplniysqiglimliGI--------------------------- 917
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 934 VKKNAIMMIDFAlEAEREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLL 1013
Cdd:COG0841 918 VVKNAILLVDFA-NQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLL 996
|
1050
....*....|....*....
gi 1891041650 1014 TLFTTPVIYLGFARMAQRW 1032
Cdd:COG0841 997 TLFVVPVLYVLLDRLRRRL 1015
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1026 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 953.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 3 PSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 83 SSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPmPPVYSKVNPADAPVMTIAVTSP--SLPVIKVHDLVEN 160
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQ-RPGISVIKTSLGPIMVLAVTSPdgSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 161 RLAPKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAE 240
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 241 YQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQIL 320
Cdd:pfam00873 240 FEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 321 ADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVV 400
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 401 DDAIVMIENIARYVEE-GDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSL 479
Cdd:pfam00873 400 DDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 480 TLTPMMSARLLRPETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTG 559
Cdd:pfam00873 480 TLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 560 LVQVITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGV--DGANASLNTGRMQITLKPFAQR---HASATEVIAR 634
Cdd:pfam00873 560 VFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFafSGDNNGPNSGDAFISLKPWKERpgpEKSVQALIER 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 635 LGDLNRQVPGITAYMQPVQDLTIED--RVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQ 712
Cdd:pfam00873 640 LRKALKQIPGANVFLFQPIQLRGLGtiSGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVN 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 713 IDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPgsttttsatgtaATTTVQ 792
Cdd:pfam00873 720 IDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR------------NPYGKM 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 793 VPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFL 872
Cdd:pfam00873 788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPIL 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 873 ILAAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQ 952
Cdd:pfam00873 868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQE 947
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1891041650 953 GLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFA 1026
Cdd:pfam00873 948 GKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
4-1023 |
5.62e-154 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 485.39 E-value: 5.62e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 4 SRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSS 83
Cdd:TIGR00915 2 AKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 84 SSG-GASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVysKVNPA-DAPVMTIAVTSP--SLPVIKVHDLVE 159
Cdd:TIGR00915 82 SDSdGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGV--RVEKAsSNFLMVIGLVSDdgSMTKEDLSDYAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 160 NRLAPKLSQVDGVGLVSIAGGRRpAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSF------DGAQRASTIDAND 233
Cdd:TIGR00915 160 SNMVDPLSRLEGVGDVQLFGSQY-AMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavPGQQLNATIIAQT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 234 QLRSAAEYQNLII-AWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLP 312
Cdd:TIGR00915 239 RLQTPEQFENILLkVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 313 ASIDVQILADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMAL 392
Cdd:TIGR00915 319 QGMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAM 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 393 TISTGFVVDDAIVMIENIARYV-EEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAI 471
Cdd:TIGR00915 399 VLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 472 LISAFVSLTLTPMMSARLLRP----ETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVV 547
Cdd:TIGR00915 479 ALSVLVALILTPALCATMLKPiekgEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVR 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 548 VPKGFFPVQDTGLVQVITEATQSTSfdamSERQQR-LAEV---FLKDPdVDHIASFIGVDG---ANASLNTGRMQITLKP 620
Cdd:TIGR00915 559 LPTSFLPDEDQGVFMTIVQLPAGAT----AERTQAvLAQVtkyLLAKE-KANVESVFTVNGfsfAGRGQNMGMAFIRLKD 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 621 FAQRHASATEVIARLGDLNRQVPGIT-AYMQPVQDLTIEDRVSKTQYQFLL---SSPDSTDLQKANDALLARLKQLPQLA 696
Cdd:TIGR00915 634 WEERTGKENSVFAIAGRATGHFMQIKdAMVIAFVPPAILELGNATGFDFFLqdrAGLGHEALLQARNQLLGLAAQNPALT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 697 DVASDLQNQGLQAWVQIDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPgs 776
Cdd:TIGR00915 714 RVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVR-- 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 777 ttttsatgtaATTTVQVPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQ 856
Cdd:TIGR00915 792 ----------NASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGM 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 857 GAAEAFSNSLSSTLFLIlaAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKK 936
Cdd:TIGR00915 862 SYEERLSGSQAPALYAL--SLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAK 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 937 NAIMMIDFALEAeREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLF 1016
Cdd:TIGR00915 940 NAILIVEFAKEL-MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIF 1018
|
....*..
gi 1891041650 1017 TTPVIYL 1023
Cdd:TIGR00915 1019 FVPLFYV 1025
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
198-486 |
1.34e-05 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 49.39 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 198 GLSLDDVRSAIasanvNQAKGSFdgAQRASTIDANDQLRSAaeYQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADT 277
Cdd:NF037998 339 LMKIDEVFKVL-----NGLILSF--NDKTTTSNFNQYLDEK--IKNYILNNDTINGTKTGAGAGSNTNSNQLIVATSTET 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 278 TPGVILNVQRQPGANVIQTVDRVKallpklqgTLPASIDVQILAdrtttirASVddteIELL-LAIALVVAVIFLFLRSG 356
Cdd:NF037998 410 IARTIEALINQTTSGFTFKVNGIS--------EFNPVVTLLMLI-------ASI----IFLLiLAIAIMIYLLFAYRLLG 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 357 SATLIPSVAvplSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTII 436
Cdd:NF037998 471 LFAIIIALT---SISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKRSIEESFKIANKETIGII 547
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1891041650 437 slTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLTPMMS 486
Cdd:NF037998 548 --VDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMI 595
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
3-1042 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 1374.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 3 PSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTS 82
Cdd:PRK10503 12 PSRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 83 SSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVENRL 162
Cdd:PRK10503 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 163 APKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQ 242
Cdd:PRK10503 172 AQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYR 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 243 NLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILAD 322
Cdd:PRK10503 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSD 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 323 RTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDD 402
Cdd:PRK10503 332 RTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDD 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 403 AIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLT 482
Cdd:PRK10503 412 AIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLT 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 483 PMMSARLLRPETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGLVQ 562
Cdd:PRK10503 492 PMMCARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQ 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 563 VITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGANASLNTGRMQITLKPFAQRHASATEVIARLGDLNRQV 642
Cdd:PRK10503 572 GTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAKV 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 643 PGITAYMQPVQDLTIEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGRLG 722
Cdd:PRK10503 652 PGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLG 731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 723 VTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTTsatgtaatttvqVPLSSVAQIV 802
Cdd:PRK10503 732 ISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGV------------VPLSSIATIE 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 803 ERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTMYI 882
Cdd:PRK10503 800 QRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYI 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 883 VLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQGLDPRAAIHQ 962
Cdd:PRK10503 880 VLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQ 959
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 963 ASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFARMAQRWRERRGVKRET 1042
Cdd:PRK10503 960 ACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHEEE 1039
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1027 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1200.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 4 SRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSS 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 84 SSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVENRLA 163
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 164 PKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQN 243
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 244 LIIAWK-NGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILAD 322
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 323 RTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDD 402
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 403 AIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLT 482
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 483 PMMSARLLRpeTEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGLVQ 562
Cdd:NF033617 481 PMMCSRLLK--ANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIF 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 563 VITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGaNASLNTGRMQITLKPFAQRHASATEVIARLGDLNRQV 642
Cdd:NF033617 559 GMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGG-NPGDNTGFGIINLKPWDERDVSAQEIIDRLRPKLAKV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 643 PGITAYMQPVQDLTIEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGRLG 722
Cdd:NF033617 638 PGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 723 VTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTtsatgtaatttvQVPLSSVAQIV 802
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGK------------LVPLSTLAKIE 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 803 ERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKaEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTMYI 882
Cdd:NF033617 786 ERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALD-QAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYL 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 883 VLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQGLDPRAAIHQ 962
Cdd:NF033617 865 VLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQ 944
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1891041650 963 ASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFAR 1027
Cdd:NF033617 945 AAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1032 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1088.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 1 MNPSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 81 TSSSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLpMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVEN 160
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 161 RLAPKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAE 240
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 241 YQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQIL 320
Cdd:COG0841 240 FENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 321 ADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVV 400
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 401 DDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLT 480
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 481 LTPMMSARLLRPETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGL 560
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 561 VQVITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGANASLNTGRMQITLKPFAQRHASATEVIARLGDLNR 640
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 641 QVPGITAYMQPVQDltiEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGR 720
Cdd:COG0841 640 KIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAA 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 721 LGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTtsatgtaatttvQVPLSSVAQ 800
Cdd:COG0841 717 LGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGE------------MVPLSSVAT 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 801 IVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTM 880
Cdd:COG0841 785 IEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLV 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 881 YIVLGVLYESYIHPVTILSTLPSA---------------------------GVgallalliggldlgiiaiigivlligi 933
Cdd:COG0841 865 YLVLAAQFESFIQPLIILLTVPLAligallgllltgtplniysqiglimliGI--------------------------- 917
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 934 VKKNAIMMIDFAlEAEREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLL 1013
Cdd:COG0841 918 VVKNAILLVDFA-NQLREEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLL 996
|
1050
....*....|....*....
gi 1891041650 1014 TLFTTPVIYLGFARMAQRW 1032
Cdd:COG0841 997 TLFVVPVLYVLLDRLRRRL 1015
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
7-1036 |
0e+00 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 1039.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 7 FIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSSSSG 86
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 87 GASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVENRLAPKL 166
Cdd:PRK10614 87 GSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 167 SQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQNLII 246
Cdd:PRK10614 167 SQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLII 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 247 AWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILADRTTT 326
Cdd:PRK10614 247 HYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPT 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 327 IRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVM 406
Cdd:PRK10614 327 IRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 407 IENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLTPMMS 486
Cdd:PRK10614 407 LENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMC 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 487 ARLLRPETEQKHSRLgTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGLVQVITE 566
Cdd:PRK10614 487 AWLLKSSKPREQKRL-RGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFIQ 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 567 ATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGvdgaNASLNTGRMQITLKPFAQRHASATEVIARLGDLNRQVPGIT 646
Cdd:PRK10614 566 ADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG----GSRVNSGMMFITLKPLSERSETAQQVIDRLRVKLAKEPGAN 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 647 AYMQPVQDLTIEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDREAAGRLGVTVS 726
Cdd:PRK10614 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQ 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 727 SIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVpgsttttsatgtAATTTVQVPLSSVAQIVERPA 806
Cdd:PRK10614 722 AANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFV------------INNEGKAIPLSYFAKWQPANA 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 807 ALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFLILAAVVTMYIVLGV 886
Cdd:PRK10614 790 PLSVNHQGLSAASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGI 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 887 LYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQGLDPRAAIHQASLL 966
Cdd:PRK10614 870 LYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIFQACLL 949
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 967 RFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFARMAQRWRERR 1036
Cdd:PRK10614 950 RFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKP 1019
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1026 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 953.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 3 PSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 83 SSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPmPPVYSKVNPADAPVMTIAVTSP--SLPVIKVHDLVEN 160
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQ-RPGISVIKTSLGPIMVLAVTSPdgSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 161 RLAPKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAE 240
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 241 YQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQIL 320
Cdd:pfam00873 240 FEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 321 ADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVV 400
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 401 DDAIVMIENIARYVEE-GDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSL 479
Cdd:pfam00873 400 DDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 480 TLTPMMSARLLRPETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTG 559
Cdd:pfam00873 480 TLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 560 LVQVITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGV--DGANASLNTGRMQITLKPFAQR---HASATEVIAR 634
Cdd:pfam00873 560 VFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFafSGDNNGPNSGDAFISLKPWKERpgpEKSVQALIER 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 635 LGDLNRQVPGITAYMQPVQDLTIED--RVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQ 712
Cdd:pfam00873 640 LRKALKQIPGANVFLFQPIQLRGLGtiSGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVN 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 713 IDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPgsttttsatgtaATTTVQ 792
Cdd:pfam00873 720 IDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR------------NPYGKM 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 793 VPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAAEAFSNSLSSTLFL 872
Cdd:pfam00873 788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPIL 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 873 ILAAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQ 952
Cdd:pfam00873 868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQE 947
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1891041650 953 GLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFA 1026
Cdd:pfam00873 948 GKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
4-1023 |
5.62e-154 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 485.39 E-value: 5.62e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 4 SRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSS 83
Cdd:TIGR00915 2 AKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 84 SSG-GASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVysKVNPA-DAPVMTIAVTSP--SLPVIKVHDLVE 159
Cdd:TIGR00915 82 SDSdGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGV--RVEKAsSNFLMVIGLVSDdgSMTKEDLSDYAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 160 NRLAPKLSQVDGVGLVSIAGGRRpAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSF------DGAQRASTIDAND 233
Cdd:TIGR00915 160 SNMVDPLSRLEGVGDVQLFGSQY-AMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavPGQQLNATIIAQT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 234 QLRSAAEYQNLII-AWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLP 312
Cdd:TIGR00915 239 RLQTPEQFENILLkVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 313 ASIDVQILADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMAL 392
Cdd:TIGR00915 319 QGMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAM 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 393 TISTGFVVDDAIVMIENIARYV-EEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAI 471
Cdd:TIGR00915 399 VLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAM 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 472 LISAFVSLTLTPMMSARLLRP----ETEQKHSRLGTWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVV 547
Cdd:TIGR00915 479 ALSVLVALILTPALCATMLKPiekgEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVR 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 548 VPKGFFPVQDTGLVQVITEATQSTSfdamSERQQR-LAEV---FLKDPdVDHIASFIGVDG---ANASLNTGRMQITLKP 620
Cdd:TIGR00915 559 LPTSFLPDEDQGVFMTIVQLPAGAT----AERTQAvLAQVtkyLLAKE-KANVESVFTVNGfsfAGRGQNMGMAFIRLKD 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 621 FAQRHASATEVIARLGDLNRQVPGIT-AYMQPVQDLTIEDRVSKTQYQFLL---SSPDSTDLQKANDALLARLKQLPQLA 696
Cdd:TIGR00915 634 WEERTGKENSVFAIAGRATGHFMQIKdAMVIAFVPPAILELGNATGFDFFLqdrAGLGHEALLQARNQLLGLAAQNPALT 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 697 DVASDLQNQGLQAWVQIDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPgs 776
Cdd:TIGR00915 714 RVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVR-- 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 777 ttttsatgtaATTTVQVPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQ 856
Cdd:TIGR00915 792 ----------NASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGM 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 857 GAAEAFSNSLSSTLFLIlaAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKK 936
Cdd:TIGR00915 862 SYEERLSGSQAPALYAL--SLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAK 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 937 NAIMMIDFALEAeREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLF 1016
Cdd:TIGR00915 940 NAILIVEFAKEL-MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIF 1018
|
....*..
gi 1891041650 1017 TTPVIYL 1023
Cdd:TIGR00915 1019 FVPLFYV 1025
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
29-1036 |
3.65e-147 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 466.81 E-value: 3.65e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 29 YRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSSSSGGASVITLRFSLGLSLDVAEQEV 108
Cdd:COG3696 31 LRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSISRFGLSVVTVIFEDGTDIYWARQLV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 109 QAAINAGSNLLPSDlpmppvyskVNPADAP-------VMTIAVTSPSlpviKVHDLVENR------LAPKLSQVDGVGLV 175
Cdd:COG3696 111 LERLQQVREQLPAG---------VTPELGPistglgeIYQYTLESDP----GKYSLMELRtlqdwvIRPQLRSVPGVAEV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 176 SIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQNLIIAWKNGNPLR 255
Cdd:COG3696 178 NSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSLEDIENIVVKTRNGTPVL 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 256 LSDVAQIVDDAEnLRL--AAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILADRTTTIRASVDD 333
Cdd:COG3696 258 LRDVAEVRIGPA-PRRgaATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVKIVPFYDRSDLIDRAIHT 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 334 TEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIENIARY 413
Cdd:COG3696 337 VTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVENILRR 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 414 VEE------GDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLTPMMSA 487
Cdd:COG3696 417 LEEnraagtPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLAS 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 488 RLLRPETEQKHSRLGTWfgekfeaMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTG--LVQVIT 565
Cdd:COG3696 497 LLLRGKVPEKENPLVRW-------LKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGdlLVMATL 569
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 566 EAtqSTSFDAMSERQQRLAEVFLKDPDVDHIASFIG---VDGANASLNTGRMQITLKPFAQRHASAT--EVIARLGDLNR 640
Cdd:COG3696 570 PP--GISLEESVELGQQVERILKSFPEVESVVSRTGraeDATDPMGVNMSETFVILKPRSEWRSGRTkeELIAEMREALE 647
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 641 QVPGIT-AYMQPvqdltIEDRV------SKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQI 713
Cdd:COG3696 648 QIPGVNfNFSQP-----IQMRVdellsgVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRI 722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 714 DREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTtsatgtaatttvQV 793
Cdd:COG3696 723 DRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGA------------QV 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 794 PLSSVAQIVERPAALAINHVAQFPAATISFNLPpGVALGDAVQAIKAE-QAKLDLPISVETSFQGAAEAFSNSLSSTLFL 872
Cdd:COG3696 791 PLSQVADIEVVEGPNQISRENGRRRIVVQANVR-GRDLGSFVAEAQAKvAEQVKLPPGYYIEWGGQFENLQRATARLAIV 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 873 ILAAVVTMYIVLGVLYESYIHPVTILSTLPSA---------------------------GVGALlalliggldlgiiaii 925
Cdd:COG3696 870 VPLALLLIFLLLYLAFGSVRDALLILLNVPFAliggvlalwlrgmplsvsagvgfialfGVAVL---------------- 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 926 givlligivkkNAIMMIDFALEAeREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVG 1005
Cdd:COG3696 934 -----------NGVVLVSYINQL-RAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIG 1001
|
1050 1060 1070
....*....|....*....|....*....|.
gi 1891041650 1006 GLIVSQLLTLFTTPVIYlgfaRMAQRWRERR 1036
Cdd:COG3696 1002 GLITSTLLTLLVLPALY----LLFGRRRLRR 1028
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1027 |
2.39e-137 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 440.43 E-value: 2.39e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 1 MNPSRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 81 TSSSSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPmPPVYSKVNPADAPVMTIAVTSPSLPVIKVHDLVEN 160
Cdd:PRK09579 81 TSVSRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAE-DPVLSKEAADASALMYISFYSEEMSNPQITDYLSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 161 RLAPKLSQVDGVGLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAE 240
Cdd:PRK09579 160 VIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 241 YQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQIL 320
Cdd:PRK09579 240 FAAIPVKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 321 ADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVV 400
Cdd:PRK09579 320 YDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 401 DDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLT 480
Cdd:PRK09579 400 DDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 481 LTPMMSARLLRPetEQKHSRLGTWFGEKFEAMIQGYGRALDWVLD-RPVLTLLGFAATLALTALLyVVVPKGFFPVQDTG 559
Cdd:PRK09579 480 LSPMMCALLLRH--EENPSGLAHRLDRLFERLKQRYQRALHGTLNtRPVVLVFAVIVLALIPVLL-KFTQSELAPEEDQG 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 560 LVQVITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIGVDGanasLNTGRMQITLKPFAQRHASATEVIARLGDLN 639
Cdd:PRK09579 557 IIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNG----VQSGIGGFLLKPWNERERTQMELLPLVQAKL 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 640 RQVPG--ITAYMQPVQDLTIEDrvskTQYQFLLSSP-DSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQIDRE 716
Cdd:PRK09579 633 EEIPGlqIFGFNLPSLPGTGEG----LPFQFVINTAnDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRA 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 717 AAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTTsatgtaatttvqVPLS 796
Cdd:PRK09579 709 KAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQL------------LPLS 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 797 SVAQIVERPAALAINHVAQFPAATISFNlpPGVALGDA---VQAIKAEQAkldlPISVETSFQGAAEAFSNSLSSTLFLI 873
Cdd:PRK09579 777 TLITLSDRARPRQLNQFQQLNSAIISGF--PIVSMGEAietVQQIAREEA----PEGFAFDYAGASRQYVQEGSALWVTF 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 874 LAAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFALEAEREQG 953
Cdd:PRK09579 851 GLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQG 930
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1891041650 954 LDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYLGFAR 1027
Cdd:PRK09579 931 LSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAK 1004
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
4-1035 |
1.69e-127 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 414.63 E-value: 1.69e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 4 SRPFIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSS 83
Cdd:PRK09577 2 ARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSAT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 84 SSGGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVYSKvNPADAPVMTIAVTSPS--LPVIKVHDLVENR 161
Cdd:PRK09577 82 SSAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVE-KAADNIQLIVSLTSDDgrLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 162 LAPKLSQVDGVGLVSIAGGRRpAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSF------DGAQRASTIDANDQL 235
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGAEY-AMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIgrsavpDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 236 RSAAEYQNLIIAWK-NGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPAS 314
Cdd:PRK09577 240 KTPEDFGAIALRARaDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 315 IDVQILADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTI 394
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 395 STGFVVDDAIVMIENIAR-YVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILI 473
Cdd:PRK09577 400 AIGILVDDAIVVVENVERlMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 474 SAFVSLTLTPMMSARLLRPETEQKHSRLG--TWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKG 551
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHHEKRGffGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 552 FFPVQDTGLVQVITEATQSTSfdaMSERQQRLAEV---FLKDPDVDHIASFIGVDGANASLNTGRMQITLKPFAQRHASA 628
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTP---LAETMQSVREVesyLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAAR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 629 TEVIARLGDLNRQ---VPGITAY---MQPVQDLTiedrvSKTQYQFLLSSPDSTD---LQKANDALLARLKQLPQLADVA 699
Cdd:PRK09577 637 DHVQAIVARINERfagTPNTTVFamnSPALPDLG-----STSGFDFRLQDRGGLGyaaFVAAREQLLAEGAKDPALTDLM 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 700 SDLQNQGLQAWVQIDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTT 779
Cdd:PRK09577 712 FAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGE 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 780 TsatgtaatttvqVPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSFQGAA 859
Cdd:PRK09577 792 M------------VPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFE 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 860 EAFSNSLSSTLFLIlaAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAI 939
Cdd:PRK09577 860 ERLSGAQAPMLFAL--SVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAI 937
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 940 MMIDFA--LEAEREQGLDpraAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFT 1017
Cdd:PRK09577 938 LIVEVAkdLVAQRMSLAD---AALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFL 1014
|
1050
....*....|....*...
gi 1891041650 1018 TPVIYLGFARMAQRWRER 1035
Cdd:PRK09577 1015 VPLFFVVVGRLFDVGPRR 1032
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
7-1023 |
2.05e-111 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 371.08 E-value: 2.05e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 7 FIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSSSSG 86
Cdd:PRK10555 5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 87 -GASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVysKVNPA-DAPVMTIAVTSP--SLPVIKVHDLVENRL 162
Cdd:PRK10555 85 tGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGV--TVRKTgDTNILTIAFVSTdgSMDKQDIADYVASNI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 163 APKLSQVDGVGLVSiAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKG------SFDGAQRASTIDANDQLR 236
Cdd:PRK10555 163 QDPLSRVNGVGDID-AYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGqlggtpSVDKQALNATINAQSLLQ 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 237 SAAEYQNLII-AWKNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASI 315
Cdd:PRK10555 242 TPEQFRDITLrVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 316 DVQILADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTIS 395
Cdd:PRK10555 322 EYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 396 TGFVVDDAIVMIENIARYV-EEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILIS 474
Cdd:PRK10555 402 IGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 475 AFVSLTLTPMMSARLLRP-ETEQKHSRLG--TWFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKG 551
Cdd:PRK10555 482 VLVAMILTPALCATLLKPlKKGEHHGQKGffGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPTS 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 552 FFPVQDTGL----VQVITEATQSTSFDAMserqQRLAEVFLKDP--DVDHIASFIGVDGANASLNTGRMQITLKPFAQRH 625
Cdd:PRK10555 562 FLPLEDRGMfttsVQLPSGSTQQQTLKVV----EKVEKYYFTHEkdNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 626 A---SATEVIARLGDLNRQV----------PGITAYMQPVQ-DLTIEDRVSKTQyqfllsspdsTDLQKANDALLARLKQ 691
Cdd:PRK10555 638 SktgTSFAIIERATKAFNKIkearviasspPAISGLGSSAGfDMELQDHAGAGH----------DALMAARNQLLALAAK 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 692 LPQLADVASDLQNQGLQAWVQIDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGL 771
Cdd:PRK10555 708 NPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLW 787
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 772 YVPGSTTTtsatgtaatttvQVPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISV 851
Cdd:PRK10555 788 YVRNKDGG------------MVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGL 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 852 ETSFQGAAEAFSNSLSSTLFLILAAVVtmYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLI 931
Cdd:PRK10555 856 EWTAMSYQERLSGAQAPALYAISLLVV--FLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVI 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 932 GIVKKNAIMMIDFALEAErEQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQ 1011
Cdd:PRK10555 934 GLSAKNAILIVEFANEMN-QKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISAT 1012
|
1050
....*....|..
gi 1891041650 1012 LLTLFTTPVIYL 1023
Cdd:PRK10555 1013 ILAIFFVPLFFV 1024
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
7-1034 |
9.17e-109 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 364.22 E-value: 9.17e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 7 FIERPVATSLLMLAILLAGLLAYRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSSS-S 85
Cdd:PRK15127 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 86 GGASVITLRFSLGLSLDVAEQEVQAAINAGSNLLPSDLPMPPVysKVNPADAPVMTIA---VTSPSLPVIKVHDLVENRL 162
Cdd:PRK15127 85 TGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGV--SVEKSSSSFLMVVgviNTDGTMTQEDISDYVAANM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 163 APKLSQVDGVGLVSIAGGRRpAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGA------QRASTIDANDQLR 236
Cdd:PRK15127 163 KDPISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTppvkgqQLNASIIAQTRLT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 237 SAAEYQNLIIAW-KNGNPLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASI 315
Cdd:PRK15127 242 STEEFGKILLKVnQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 316 DVQILADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTIS 395
Cdd:PRK15127 322 KIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 396 TGFVVDDAIVMIENIAR-YVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILIS 474
Cdd:PRK15127 402 IGLLVDDAIVVVENVERvMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 475 AFVSLTLTPMMSARLLRPETEQKHSRLGT----WFGEKFEAMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPK 550
Cdd:PRK15127 482 VLVALILTPALCATMLKPIAKGDHGEGKKgffgWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPS 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 551 GFFPVQDTGL----VQVITEATQstsfdamsERQQR-LAEV--FLKDPDVDHIASFIGVDG---ANASLNTGRMQITLKP 620
Cdd:PRK15127 562 SFLPDEDQGVfltmVQLPAGATQ--------ERTQKvLNEVtdYYLTKEKNNVESVFAVNGfgfAGRGQNTGIAFVSLKD 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 621 FAQRHASATEVIARLGDLNRQVPGITAYMQPVQDL-TIEDRVSKTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVA 699
Cdd:PRK15127 634 WADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLpAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDML 713
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 700 SDLQNQGL----QAWVQIDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPG 775
Cdd:PRK15127 714 VGVRPNGLedtpQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRA 793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 776 STTTtsatgtaatttvQVPLSSVAQIVERPAALAINHVAQFPAATISFNLPPGVALGDAVQAIKAEQAKLDLPISVETSF 855
Cdd:PRK15127 794 ADGQ------------MVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTG 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 856 QGAAEAFSNSLSSTLFLIlaAVVTMYIVLGVLYESYIHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVK 935
Cdd:PRK15127 862 MSYQERLSGNQAPALYAI--SLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSA 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 936 KNAIMMIDFALEAEREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTL 1015
Cdd:PRK15127 940 KNAILIVEFAKDLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAI 1019
|
1050
....*....|....*....
gi 1891041650 1016 FTTPVIYLGFARMAQRWRE 1034
Cdd:PRK15127 1020 FFVPVFFVVVRRRFSRKNE 1038
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
29-1047 |
3.04e-91 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 315.55 E-value: 3.04e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 29 YRLLPLSALPEVDYPTIQVTTLYPGASPDVISTTVTAPLERQFGQMPGLGQMTSSSSGGASVITLRFSLGLSLDVAEQEV 108
Cdd:TIGR00914 31 YNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYGLSQVTVIFKDGTDLYFARQLV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 109 QAAINAGSNLLPSDlpmppvyskVNPADAPVMT-------IAVTSPSLPVIK---VHDLVENR------LAPKLSQVDGV 172
Cdd:TIGR00914 111 NERLQQARDNLPEG---------VSPEMGPISTglgeiflYTVEAEEGARKKdggAYTLTDLRtiqdwiIRPQLRTVPGV 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 173 GLVSIAGGRRPAVRIQANPSTLAALGLSLDDVRSAIASANVNQAKGSFDGAQRASTIDANDQLRSAAEYQNLIIAWKNGN 252
Cdd:TIGR00914 182 AEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQSMDDIRNIVIATGEGV 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 253 PLRLSDVAQIVDDAENLRLAAWADTTPGVILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILADRTTTIRASVD 332
Cdd:TIGR00914 262 PIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVEIVTTYDRSQLVDAAIA 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 333 DTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTIstGFVVDDAIVMIENIAR 412
Cdd:TIGR00914 342 TVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGALDF--GLIVDGAVVIVENAHR 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 413 YVEEGD----------SPMEAAFKGSRQIG-FTIISLTVSLIaVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTL 481
Cdd:TIGR00914 420 RLAEAQhhhgrqltlkERLHEVFAASREVRrPLIFGQLIITL-VFLPIFTLTGVEGKMFHPMAFTVVLALAGAMILSLTF 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 482 TPMMSARLLRPETEQKHSRLGTWfgekfeaMIQGYGRALDWVLDRPVLTLLGFAATLALTALLYVVVPKGFFPVQDTGLV 561
Cdd:TIGR00914 499 VPAAVALFIRGKVAEKENRLMRV-------LKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSLNEGDL 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 562 QVITEATQSTSFDAMSERQQRLAEVFLKDPDVDHIASFIG---VDGANASLNTGRMQITLKPFAQ---RHASATEVIARL 635
Cdd:TIGR00914 572 AYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGtaeIATDPMPPNASDTYIILKPESQwpeGKKTKEDLIEEI 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 636 GDLNRQVPGIT-AYMQPVQdLTIEDRVS--KTQYQFLLSSPDSTDLQKANDALLARLKQLPQLADVASDLQNQGLQAWVQ 712
Cdd:TIGR00914 652 QEATVRIPGNNyEFTQPIQ-MRFNELISgvRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAADVKVEQTTGLPYLTVE 730
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 713 IDREAAGRLGVTVSSIDTALYNAFGQRLISTIYTQASQYRVVLEAASEFRSGPRALEGLYVPGSTTTTSATGtaatttvQ 792
Cdd:TIGR00914 731 IDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSEDARKQ-------F 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 793 VPLSSVAQIVERPAALAINHVAQFPAATISFNLPpGVALGDAV-QAIKAEQAKLDLPISVETSFQGAaeaFSNSLSSTLF 871
Cdd:TIGR00914 804 IPLSDVADLRVSPGPNQISRENGKRRVVVSANVR-GRDLGSFVdDAKKAIAEQVKLPPGYWITWGGQ---FEQLQSATKR 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 872 LILAAVVTMYIVLGVLYESY---IHPVTILSTLPSAGVGALLALLIGGLDLGIIAIIGIVLLIGIVKKNAIMMIDFaLEA 948
Cdd:TIGR00914 880 LQIVVPVTLLLIFVLLYAAFgnvKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF-IRK 958
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 949 EREQGLDPRAAIHQASLLRFRPILMTTMAALLGALPLMLGTGVGHELRHPLGVTMVGGLIVSQLLTLFTTPVIYlgfaRM 1028
Cdd:TIGR00914 959 LLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALY----RL 1034
|
1050
....*....|....*....
gi 1891041650 1029 AqrWRERRGVKRETRAAAQ 1047
Cdd:TIGR00914 1035 V--HRRRHKGRKEHEPLEG 1051
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
281-534 |
1.02e-19 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 94.93 E-value: 1.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 281 VILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQI---LADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGS 357
Cdd:COG1033 164 IVVTLDPDPLSSDLDRKEVVAEIRAIIAKYEDPGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLR 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 358 ATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIIS 437
Cdd:COG1033 244 GVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLL 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 438 LTVSLIAVLIPLLFMgDVvgRLFHEFAITLAVAILISAFVSLTLTPMMSARLLRPETEQKHSRLGTWFGEKFEAMIqgyg 517
Cdd:COG1033 324 TSLTTAIGFLSLLFS-DI--PPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLA---- 396
|
250
....*....|....*..
gi 1891041650 518 ralDWVLDRPVLTLLGF 534
Cdd:COG1033 397 ---RFVLRRPKVILVVA 410
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
281-497 |
3.12e-17 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 87.22 E-value: 3.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 281 VILNVQRQPGANVIQTVDRVKALLPKLQGTLPASIDVQILADRTTTIRASVDDTEIE-LLLAIALVVAVIFLFLRSGSAT 359
Cdd:COG1033 553 VTVRLKDLDSEEIKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINESVIESQIRsLLLALLLIFLLLLLAFRSLRLG 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 360 LIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLT 439
Cdd:COG1033 633 LISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTS 712
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1891041650 440 VSLIAVLIPLLFMGdvvGRLFHEFAITLAVAILISAFVSLTLTPMMsARLLRPETEQK 497
Cdd:COG1033 713 LTLAAGFGVLLFSS---FPPLADFGLLLALGLLVALLAALLLLPAL-LLLLDPRIAKK 766
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
295-533 |
7.75e-11 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 66.33 E-value: 7.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 295 QTVDRVKALLPKLQGTLPASIDVQI---LADRTTTIRASVDDTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLV 371
Cdd:COG2409 129 EAAEAVDALRDAVAAAPAPGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVG 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 372 GTFGVMYLAG--FSINNLTLMALT-ISTGFVVDDAIVMienIARYVEE---GDSPMEAAFKGSRQIGFTIIS--LTVslI 443
Cdd:COG2409 209 VALGLLALLAafTDVSSFAPNLLTmLGLGVGIDYALFL---VSRYREElraGEDREEAVARAVATAGRAVLFsgLTV--A 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 444 AVLIPLLFMGDVVgrlFHEFAITLAVAILISAFVSLTLTP----MMSARLLRPeteqkhsrLGTWFGEKFEAMIQGYGRA 519
Cdd:COG2409 284 IALLGLLLAGLPF---LRSMGPAAAIGVAVAVLAALTLLPallaLLGRRVFWP--------RRPRRRRAAAPESGFWRRL 352
|
250
....*....|....
gi 1891041650 520 LDWVLDRPVLTLLG 533
Cdd:COG2409 353 ARAVVRRPVPVLVA 366
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
309-482 |
1.25e-09 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 61.53 E-value: 1.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 309 GTLPASIdvQILADRT---TTIRASVDDTEIELLLAIALVVAviFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSin 385
Cdd:TIGR01129 224 GALPAPL--QILEERTigpSLGADSIEAGIKAGLIGLVLVLV--FMILYYRLFGLIAAIALVINIVLILAILSAFGAT-- 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 386 nLTL-----MALTIstGFVVDDAIVMIENIARYVEEGDSP---MEAAFKGSRQigfTIISLTV-SLIAVLIPLLF-MGDV 455
Cdd:TIGR01129 298 -LTLpgiagLILTI--GMAVDANVLIYERIKEELRLGKSVrqaIEAGFERAFS---TIFDANItTLIAALILYVFgTGPV 371
|
170 180
....*....|....*....|....*..
gi 1891041650 456 VGrlfheFAITLAVAILISAFVSLTLT 482
Cdd:TIGR01129 372 KG-----FAVTLAIGIIASLFTALVFT 393
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
309-491 |
1.31e-08 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 58.59 E-value: 1.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 309 GTLPASIDVQiladRTTTI-----RASVDDTEIELLLAIALVVAVIFLFLRsgsatlIPSVAVPLSLVG----TFGVMYL 379
Cdd:COG0342 247 GALPAPLEIV----EERTVgptlgADSIEKGLIAGLIGLLLVALFMLLYYR------LPGLVANIALALnvvlLLGVLSL 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 380 AGFsinNLTL-----MALTISTGfvVDDAIVMIEniaRYVEE---GDSP---MEAAFKGSRqigFTII-SLTVSLIAVLI 447
Cdd:COG0342 317 LGA---TLTLpgiagIILTIGMA--VDANVLIFE---RIREElraGRSLraaIEAGFKRAF---STILdANVTTLIAAVV 385
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1891041650 448 pLLFM--GDVVGrlfheFAITLAVAILISAFVSLTLTPMMSARLLR 491
Cdd:COG0342 386 -LFVLgtGPVKG-----FAVTLILGILISMFTAVPVTRPLLNLLLG 425
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
326-479 |
4.93e-08 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 54.18 E-value: 4.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 326 TIRASVDDTEIE---LLLAIALVVAVIFLFLRSGSATLIPSVAVPLS-LVGTFGVMYLAGFSINNLTLMALTISTGFVVD 401
Cdd:TIGR00916 36 TVGPTLGGELIKagiIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 402 DAIV----MIENIARYveEGDSPMEAAFKGSRQIGFTIISLTV-SLIAVLIPLLFMGDVVgrlfHEFAITLAVAILISAF 476
Cdd:TIGR00916 116 DTVVifdrIREELRKY--KGRTFREAINLGINQTLSRIIDTNVtTLLAVLALYVFGGGAI----KGFALTLGIGVIAGTY 189
|
...
gi 1891041650 477 VSL 479
Cdd:TIGR00916 190 SSI 192
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
309-491 |
7.38e-08 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 56.78 E-value: 7.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 309 GTLPASIDVQiladRTTTIRAS-----VDDTEIELLLAIALVVavIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFS 383
Cdd:PRK13024 242 GALPAPLKII----ESRSVGPTlgqdaIDAGIIAGIIGFALIF--LFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAV 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 384 INNLTLMALTISTGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTII--SLTvSLIAVLIplLFM---GDVVGr 458
Cdd:PRK13024 316 LTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILdsNIT-TLIAAAI--LFFfgtGPVKG- 391
|
170 180 190
....*....|....*....|....*....|...
gi 1891041650 459 lfheFAITLAVAILISAFVSLTLTPMMSARLLR 491
Cdd:PRK13024 392 ----FATTLIIGILASLFTAVFLTRLLLELLVK 420
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
309-485 |
9.76e-08 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 56.00 E-value: 9.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 309 GTLPASidVQILADRT-------TTIRASVddteIELLLAIALVVAVIFLFLR-SGsatLIPSVAVPLSLVGTFGVMYLA 380
Cdd:PRK05812 273 GALPAP--LEIVEERTigpslgaDSIRAGL----IAGLIGLALVLLFMILYYRlFG---LIANIALVANLVLILAVLSLL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 381 GFSinnLTL-----MALTIstGFVVDDAIVMIENIARYVEEGDSP---MEAAFKGSRQigfTII-SLTVSLIAVLIpLLF 451
Cdd:PRK05812 344 GAT---LTLpgiagIVLTI--GMAVDANVLIFERIREELREGRSLrsaIEAGFKRAFS---TILdSNITTLIAAII-LYA 414
|
170 180 190
....*....|....*....|....*....|....*.
gi 1891041650 452 M--GDVVGrlfheFAITLAVAILISAFVSLTLTPMM 485
Cdd:PRK05812 415 LgtGPVKG-----FAVTLGIGILTSMFTAITVTRAL 445
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
309-491 |
6.32e-07 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 53.47 E-value: 6.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 309 GTLPAsiDVQILADRTTTIRASVDDTEIELLLAI-ALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNL 387
Cdd:PRK13023 254 GALPQ--AVTVLEERTIASALGEDYASAAVLAALlAALVVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLA 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 388 TLMALTISTGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVS-LIAVLIPLLFMGDVVgrlfHEFAIT 466
Cdd:PRK13023 332 SIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVDANLTtLIAALVLFLLGSGTV----HGFALT 407
|
170 180
....*....|....*....|....*
gi 1891041650 467 LAVAILISAFVSLTLTPMMSARLLR 491
Cdd:PRK13023 408 VAIGIGTTLFTTLTFTRLLIAQWVR 432
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
338-483 |
9.56e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 52.29 E-value: 9.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 338 LLLAIALVVAVIFLFL--RSGSATLIPSVAVPLSLVGTFGVM----YLAGFSINNLT---LMALTISTGfvVDDAIVMIE 408
Cdd:pfam03176 146 LIEAVTLVVIFIILLIvyRSVVAALLPLLTVGLSLGAAQGLVailaHILGIGLSTFAlnlLVVLLIAVG--TDYALFLVS 223
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1891041650 409 NIARYVEEGDSPMEAAFKGSRQIGFTIislTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLTP 483
Cdd:pfam03176 224 RYREELRAGEDREEAVIRAVRGTGKVV---TAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLP 295
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
333-512 |
3.19e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 51.38 E-value: 3.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 333 DTEIELLLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIEniaR 412
Cdd:TIGR00921 194 DMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLN---R 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 413 YVEE---GDSPMEAAFKGSRQIGFTIIsltVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLTP--MMSA 487
Cdd:TIGR00921 271 YEEErdiGRAKGEAIVTAVRRTGRAVL---IALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPalLQSI 347
|
170 180
....*....|....*....|....*
gi 1891041650 488 RLLRPETEQKHSRLGTWFGEKFEAM 512
Cdd:TIGR00921 348 DIGREKVKKEIIAIGGKSSEIEEEL 372
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
198-486 |
1.34e-05 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 49.39 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 198 GLSLDDVRSAIasanvNQAKGSFdgAQRASTIDANDQLRSAaeYQNLIIAWKNGNPLRLSDVAQIVDDAENLRLAAWADT 277
Cdd:NF037998 339 LMKIDEVFKVL-----NGLILSF--NDKTTTSNFNQYLDEK--IKNYILNNDTINGTKTGAGAGSNTNSNQLIVATSTET 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 278 TPGVILNVQRQPGANVIQTVDRVKallpklqgTLPASIDVQILAdrtttirASVddteIELL-LAIALVVAVIFLFLRSG 356
Cdd:NF037998 410 IARTIEALINQTTSGFTFKVNGIS--------EFNPVVTLLMLI-------ASI----IFLLiLAIAIMIYLLFAYRLLG 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 357 SATLIPSVAvplSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTII 436
Cdd:NF037998 471 LFAIIIALT---SISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHLYKNKRSIEESFKIANKETIGII 547
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1891041650 437 slTVSLIAVLIPLLFMGDVVGRLFHEFAITLAVAILISAFVSLTLTPMMS 486
Cdd:NF037998 548 --VDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMI 595
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
339-483 |
2.71e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 48.29 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 339 LLAIALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIEniaRYVEEGD 418
Cdd:TIGR00921 574 IAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHLAE---RYFEERK 650
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1891041650 419 --SPMEAAFKGSRQIGFTII--SLTV-----SLIAVLIPLLfmgdvvgrlfHEFAITLAVAILISAFVSLTLTP 483
Cdd:TIGR00921 651 ehGPKEAITHTMERTGPGILfsGLTTaggflSLLLSHFPIM----------RNFGLVQGIGVLSSLTAALVVFP 714
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
309-491 |
3.71e-05 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 47.79 E-value: 3.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 309 GTLPASIDVqiLADRTTTIRASVDDTEIELLLA-IALVVAVIFLFLRSGSATLIPSVAVPLSLVGTFGVMYLAGFSinnL 387
Cdd:PRK14726 348 GALPATLTV--VEERTVGPGLGADSIAAGLVAGlIAAILVAALMIGFYGFLGVIAVIALIVNVVLIIAVLSLLGAT---L 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 388 TL-----MALTIstGFVVDDAIVMIENIARYVEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRlfhE 462
Cdd:PRK14726 423 TLpgiagIVLTI--GMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILIAAVILFFLGSGAVR---G 497
|
170 180
....*....|....*....|....*....
gi 1891041650 463 FAITLAVAILISAFVSLTLTPMMSARLLR 491
Cdd:PRK14726 498 FAVTLAVGILTTVFTAFTLTRSLVAVWLR 526
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
294-483 |
2.59e-04 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 45.14 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 294 IQTVDRVKALLPKLQGTLPASI--DVQILADrttTIRASVDDteieLLLAIALVVAVIF----LFLRSGSATLIPSVAVP 367
Cdd:COG2409 480 IDLVDRLRDAAAPALEGAEVLVggTTAVNID---ISDALADD----LPLVIPVVLGLIFllllLLFRSVVAPLKAVLTNL 552
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 368 LSLVGTFGVMYLA--------GFSINNLTLMALTISTGFVVddAIVMIENI---ARYVEE---GDSPMEAAFKGSRQIGF 433
Cdd:COG2409 553 LSLGAALGVLVLVfqhgwlllGFTPGPLDSFVPLLLFVILF--GLGMDYEVflvSRIREEydrGGGTREAVIRGLARTGR 630
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1891041650 434 TIISLTVSLIAVLIPLLFMGDVVgrlFHEFAITLAVAILISAF-VSLTLTP 483
Cdd:COG2409 631 VITSAALIMAAVFAAFATSPLVF---LKQIGFGLAVGVLLDAFvVRMLLVP 678
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
338-483 |
8.00e-04 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 43.50 E-value: 8.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 338 LLLAIALVVAVIFLFLrsgsATLIPSVAVPLSLV----GTFGVMYLAGFSINNLTLMALTISTGFVVDDAIVMIENIarY 413
Cdd:pfam02460 645 IVITLICMFIVCFLFI----PNPPCVFVITLAIAsidiGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHF--V 718
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 414 VEEGDSPMEAAFKGSRQIGFTIISLTVSLIAVLIPLLFMGDVVGRLfheFAITLAVAILISAFVSLTLTP 483
Cdd:pfam02460 719 RSRGDTPAERVVDALEALGWPVFQGGLSTILGVLVLLFVPSYMVVV---FFKTVFLVVAIGLLHGLFILP 785
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
266-478 |
2.53e-03 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 41.40 E-value: 2.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 266 AENLRLAAWADTTPGVILNVQRQPGANVIQTVDRvkallpklQGTLPASIDVqilaDRTTTIRASVDD-----TEIELLL 340
Cdd:PRK08343 202 ASGLASGPVVITVGSTGTTEEAKEEAKELYIHLR--------SGALPVKLDI----EGSGSVSPSLGEqfkkgSLIAGLL 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1891041650 341 AIALVVAVIFLFLRSgsatliPSVAVPLSLVGTFGVMYLAGFS--IN-NLTLMAL-----TISTGfvVDDAIVMIENIar 412
Cdd:PRK08343 270 ALLAVALVVFLRYRE------PRIALPMVITSLSEVIIILGFAalIGwQLDLASIagiiaVIGTG--VDDLIIITDEV-- 339
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1891041650 413 yVEEGDSPMEAAFKGSRQIGFTII-SLTVSLIAVLIPLLFMGdvVGRLfHEFAITLAVAILISAFVS 478
Cdd:PRK08343 340 -LHEGKVPSRKVFLSRIKRAFFIIfAAAATTIAAMSPLAVMG--LGDL-KGFAITTILGVLIGVLIT 402
|
|
| |
