|
Name |
Accession |
Description |
Interval |
E-value |
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
41-934 |
5.43e-35 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 145.00 E-value: 5.43e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 41 VEREYELSVVSDLVRRTAAGHPGLLLVEGQEGIGKTTLLRSLAELARAQGLRVLEARGERTGRQTPFAVAHALLHPYL-- 118
Cdd:COG3899 290 VGREAELAALLAALERARAGRGELVLVSGEAGIGKSRLVRELARRARARGGRVLRGKCDQLERGVPYAPLAQALRALLgq 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 119 ---TDLEEGPALCDGPVAEAPGTAIAAGRAPYPVGHNNVVGWPEGTYDVLAGLHRTVRRISRPGPVLLVVDDAEQADAAS 195
Cdd:COG3899 370 lpeDELAAWRARLLAALGANGRLLADLLPELELQPAPPELDPEEARNRLFRALLRLLRALAAERPLVLVLDDLHWADPAS 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 196 LRFLAHTARRLSGMPVLLAVSRCPETDAPLLDEMAT-------RPLSSVLRLRPLTERGIG-LIARRLTGRSGDQEFLAA 267
Cdd:COG3899 450 LELLEFLLRRLRDLPLLLVGTYRPEEVPPAHPLRLLlaelrraGAGVTRLELGPLSREEVAaLVADLLGAAELPAELAEL 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 268 CLSATNGIPLLVTRLLAALHREGSPLTAAGIARAHLEDVALFGRRVVATLHQQ------PVALRAAQAMAVLGDGAPFAH 341
Cdd:COG3899 530 LVERTGGNPFFLEELLRALLEEGLLRFDGGGWRWDAALAALALPDTVVDLLAArldrlpPAARRVLRLAAVLGRRFDLEL 609
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 342 CAALALLDPAVFTRAVLTLDALGLV--SSPPGTEDWYFAHPPTRETVLADMSPQLLMSTHLRAARLLHDGGAP-----AE 414
Cdd:COG3899 610 LAAVLGLSEAELAAALEELVAAGLLvpRGDAGGGRYRFRHDLVREAAYASLPPEERRALHRRIARALEARGPEpleerLF 689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 415 QVAEHLRASGTTttePWARTVLREAARTASRRGAHEHAVELLRH---CVPEDADSVDDPALMVELGLSEVRSDP------ 485
Cdd:COG3899 690 ELAHHLNRAGER---DRAARLLLRAARRALARGAYAEALRYLERaleLLPPDPEEEYRLALLLELAEALYLAGRfeeaea 766
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 486 ---EAGIGRLLRALPLLTAPDRRLTVLTALIGAMVRTGQVPRAVELLR--IRRAEAVAAGEGPAGAHVLEAHLLLTSNTS 560
Cdd:COG3899 767 lleRALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGElaLALAERLGDRRLEARALFNLGFILHWLGPL 846
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 561 HRAFRQVLDAASFGLDPAPDTAGGRALLAARAVISVSRLDGVAESLAAARAVLLHGTPPADAPATLGSAAAVLLYTDRPD 640
Cdd:COG3899 847 REALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAA 926
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 641 EAETALRRLLEGADVLDDWQHATLLALCADAYERQGALDRALAATADALRGAPAEQTDSCRALARAVRLQTLLDRDQVAE 720
Cdd:COG3899 927 AAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAA 1006
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 721 AAALAPCGPVPPLEDGWQWNELLAARGRLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKAC 800
Cdd:COG3899 1007 AAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAA 1086
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 801 GELAEEAVDGARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVL 880
Cdd:COG3899 1087 ALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLLLAL 1166
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....
gi 1906722815 881 REALETAYALEAHQLYATARRALVATGARPRRPVSRGPAALTPGELQVARLAAA 934
Cdd:COG3899 1167 AALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAA 1220
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
41-213 |
1.78e-14 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 72.15 E-value: 1.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 41 VEREYELSVVSDLVRRTAAGHPGLLLVEGQEGIGKTTLLRSLAELARAQGLRVLEARGERTGRQTPFAVAHALLHPYLTD 120
Cdd:pfam13191 3 VGREEELEQLLDALDRVRSGRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSPLLEALTREGLLRQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 121 LEEGPALCDGPVAEAPGTAIAAGRAPYPVGHNnvvgwpegtyDVLAGLHRTVRRISRPG-PVLLVVDDAEQADAASLRFL 199
Cdd:pfam13191 83 LDELESSLLEAWRAALLEALAPVPELPGDLAE----------RLLDLLLRLLDLLARGErPLVLVLDDLQWADEASLQLL 152
|
170
....*....|....
gi 1906722815 200 AHTARRLSGMPVLL 213
Cdd:pfam13191 153 AALLRLLESLPLLV 166
|
|
| HTH_LUXR |
smart00421 |
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon |
918-971 |
1.07e-13 |
|
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
Pssm-ID: 197715 [Multi-domain] Cd Length: 58 Bit Score: 66.40 E-value: 1.07e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1906722815 918 PAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:smart00421 1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQA 54
|
|
| GerE |
COG5905 |
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ... |
910-968 |
8.32e-12 |
|
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];
Pssm-ID: 444607 [Multi-domain] Cd Length: 76 Bit Score: 61.51 E-value: 8.32e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1906722815 910 PRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGR 968
Cdd:COG5905 2 MPSSSTSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNR 60
|
|
| GerE |
pfam00196 |
Bacterial regulatory proteins, luxR family; |
919-971 |
1.26e-10 |
|
Bacterial regulatory proteins, luxR family;
Pssm-ID: 425517 [Multi-domain] Cd Length: 57 Bit Score: 57.59 E-value: 1.26e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1906722815 919 AALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:pfam00196 1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVEL 53
|
|
| LuxR_C_like |
cd06170 |
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ... |
921-971 |
1.64e-10 |
|
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.
Pssm-ID: 99777 [Multi-domain] Cd Length: 57 Bit Score: 57.16 E-value: 1.64e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1906722815 921 LTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:cd06170 1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQL 51
|
|
| PRK10651 |
PRK10651 |
transcriptional regulator NarL; Provisional |
875-968 |
1.54e-05 |
|
transcriptional regulator NarL; Provisional
Pssm-ID: 182619 [Multi-domain] Cd Length: 216 Bit Score: 47.33 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 875 AARTVLREALEtayaleahQLYATARRAlvatgarPRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVET 954
Cdd:PRK10651 125 AGEMVLSEALT--------PVLAASLRA-------NRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKV 189
|
90
....*....|....
gi 1906722815 955 HLTSAYRKLGISGR 968
Cdd:PRK10651 190 HVKHMLKKMKLKSR 203
|
|
| PRK15369 |
PRK15369 |
two component system response regulator; |
918-963 |
5.77e-05 |
|
two component system response regulator;
Pssm-ID: 185267 [Multi-domain] Cd Length: 211 Bit Score: 45.45 E-value: 5.77e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1906722815 918 PAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKL 963
Cdd:PRK15369 147 PPLLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKL 192
|
|
| TMPK |
cd01672 |
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ... |
67-116 |
2.04e-03 |
|
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).
Pssm-ID: 238835 Cd Length: 200 Bit Score: 40.71 E-value: 2.04e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1906722815 67 VEGQEGIGKTTLLRSLAELARAQGLRVLEARgERTGRQTPFAVAHALLHP 116
Cdd:cd01672 5 FEGIDGAGKTTLIELLAERLEARGYEVVLTR-EPGGTPIGEAIRELLLDP 53
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG3899 |
COG3899 |
Predicted ATPase [General function prediction only]; |
41-934 |
5.43e-35 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443106 [Multi-domain] Cd Length: 1244 Bit Score: 145.00 E-value: 5.43e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 41 VEREYELSVVSDLVRRTAAGHPGLLLVEGQEGIGKTTLLRSLAELARAQGLRVLEARGERTGRQTPFAVAHALLHPYL-- 118
Cdd:COG3899 290 VGREAELAALLAALERARAGRGELVLVSGEAGIGKSRLVRELARRARARGGRVLRGKCDQLERGVPYAPLAQALRALLgq 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 119 ---TDLEEGPALCDGPVAEAPGTAIAAGRAPYPVGHNNVVGWPEGTYDVLAGLHRTVRRISRPGPVLLVVDDAEQADAAS 195
Cdd:COG3899 370 lpeDELAAWRARLLAALGANGRLLADLLPELELQPAPPELDPEEARNRLFRALLRLLRALAAERPLVLVLDDLHWADPAS 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 196 LRFLAHTARRLSGMPVLLAVSRCPETDAPLLDEMAT-------RPLSSVLRLRPLTERGIG-LIARRLTGRSGDQEFLAA 267
Cdd:COG3899 450 LELLEFLLRRLRDLPLLLVGTYRPEEVPPAHPLRLLlaelrraGAGVTRLELGPLSREEVAaLVADLLGAAELPAELAEL 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 268 CLSATNGIPLLVTRLLAALHREGSPLTAAGIARAHLEDVALFGRRVVATLHQQ------PVALRAAQAMAVLGDGAPFAH 341
Cdd:COG3899 530 LVERTGGNPFFLEELLRALLEEGLLRFDGGGWRWDAALAALALPDTVVDLLAArldrlpPAARRVLRLAAVLGRRFDLEL 609
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 342 CAALALLDPAVFTRAVLTLDALGLV--SSPPGTEDWYFAHPPTRETVLADMSPQLLMSTHLRAARLLHDGGAP-----AE 414
Cdd:COG3899 610 LAAVLGLSEAELAAALEELVAAGLLvpRGDAGGGRYRFRHDLVREAAYASLPPEERRALHRRIARALEARGPEpleerLF 689
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 415 QVAEHLRASGTTttePWARTVLREAARTASRRGAHEHAVELLRH---CVPEDADSVDDPALMVELGLSEVRSDP------ 485
Cdd:COG3899 690 ELAHHLNRAGER---DRAARLLLRAARRALARGAYAEALRYLERaleLLPPDPEEEYRLALLLELAEALYLAGRfeeaea 766
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 486 ---EAGIGRLLRALPLLTAPDRRLTVLTALIGAMVRTGQVPRAVELLR--IRRAEAVAAGEGPAGAHVLEAHLLLTSNTS 560
Cdd:COG3899 767 lleRALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGElaLALAERLGDRRLEARALFNLGFILHWLGPL 846
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 561 HRAFRQVLDAASFGLDPAPDTAGGRALLAARAVISVSRLDGVAESLAAARAVLLHGTPPADAPATLGSAAAVLLYTDRPD 640
Cdd:COG3899 847 REALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAA 926
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 641 EAETALRRLLEGADVLDDWQHATLLALCADAYERQGALDRALAATADALRGAPAEQTDSCRALARAVRLQTLLDRDQVAE 720
Cdd:COG3899 927 AAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAA 1006
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 721 AAALAPCGPVPPLEDGWQWNELLAARGRLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKAC 800
Cdd:COG3899 1007 AAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAA 1086
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 801 GELAEEAVDGARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVL 880
Cdd:COG3899 1087 ALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLLLAL 1166
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....
gi 1906722815 881 REALETAYALEAHQLYATARRALVATGARPRRPVSRGPAALTPGELQVARLAAA 934
Cdd:COG3899 1167 AALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAA 1220
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
41-213 |
1.78e-14 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 72.15 E-value: 1.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 41 VEREYELSVVSDLVRRTAAGHPGLLLVEGQEGIGKTTLLRSLAELARAQGLRVLEARGERTGRQTPFAVAHALLHPYLTD 120
Cdd:pfam13191 3 VGREEELEQLLDALDRVRSGRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSPLLEALTREGLLRQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 121 LEEGPALCDGPVAEAPGTAIAAGRAPYPVGHNnvvgwpegtyDVLAGLHRTVRRISRPG-PVLLVVDDAEQADAASLRFL 199
Cdd:pfam13191 83 LDELESSLLEAWRAALLEALAPVPELPGDLAE----------RLLDLLLRLLDLLARGErPLVLVLDDLQWADEASLQLL 152
|
170
....*....|....
gi 1906722815 200 AHTARRLSGMPVLL 213
Cdd:pfam13191 153 AALLRLLESLPLLV 166
|
|
| HTH_LUXR |
smart00421 |
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon |
918-971 |
1.07e-13 |
|
helix_turn_helix, Lux Regulon; lux regulon (activates the bioluminescence operon
Pssm-ID: 197715 [Multi-domain] Cd Length: 58 Bit Score: 66.40 E-value: 1.07e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1906722815 918 PAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:smart00421 1 LASLTPREREVLRLLAEGLTNKEIAERLGISEKTVKTHLSNIMRKLGVRSRTQA 54
|
|
| GerE |
COG5905 |
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell ... |
910-968 |
8.32e-12 |
|
Spore transcriptional regulator GerE (stand-alone HTH domain) [Cell cycle control, cell division, chromosome partitioning, Transcription];
Pssm-ID: 444607 [Multi-domain] Cd Length: 76 Bit Score: 61.51 E-value: 8.32e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1906722815 910 PRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGR 968
Cdd:COG5905 2 MPSSSTSHPSLLTKREREVLELLAEGLTNKEIARQLFISEKTVKNHVSNILRKLGVRNR 60
|
|
| CitB |
COG2197 |
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal ... |
877-971 |
9.44e-12 |
|
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription];
Pssm-ID: 441799 [Multi-domain] Cd Length: 131 Bit Score: 63.37 E-value: 9.44e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 877 RTVLREALETAYALEAHQLYATARRAL-VATGARP-------RRPVSRGPAA----LTPGELQVARLAAAGDSNVDISRT 944
Cdd:COG2197 14 REGLRALLEAEPDIEVVGEAADGEEALeLLEELRPdvvlldiRMPGMDGLEAlrrlLTPREREVLRLLAEGLSNKEIAER 93
|
90 100
....*....|....*....|....*..
gi 1906722815 945 LFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:COG2197 94 LGISERTVKTHVSNILRKLGVRNRTEL 120
|
|
| GerE |
pfam00196 |
Bacterial regulatory proteins, luxR family; |
919-971 |
1.26e-10 |
|
Bacterial regulatory proteins, luxR family;
Pssm-ID: 425517 [Multi-domain] Cd Length: 57 Bit Score: 57.59 E-value: 1.26e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1906722815 919 AALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:pfam00196 1 DSLSPREREVLRWLAAGKSNKEIADELGISEKTVKVHRSNIMRKLNVHSRVEL 53
|
|
| LuxR_C_like |
cd06170 |
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix ... |
921-971 |
1.64e-10 |
|
C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many are active as homodimers. Many are two domain proteins in which the DNA binding property of the C-terminal DNA binding domain is modulated by modifications of the N-terminal domain. For example in the case of Lux R which participates in the regulation of gene expression in response to fluctuations in cell-population density (quorum-sensing), a signaling molecule, the pheromone Acyl HSL (N-acyl derivatives of homoserine lactone), binds to the N-terminal domain and leads to LuxR dimerization. For others phophorylation of the N-terminal domain leads to multimerization, for example Escherichia coli NarL and Sinorhizobium melilot FixJ. NarL controls gene expression of many respiratory-related operons when environmental nitrate or nitrite is present under anerobic conditions. FixJ is involved in the transcriptional activation of nitrogen fixation genes. The group also includes small proteins which lack an N-terminal signaling domain, such as Bacillus subtilis GerE. GerE is dimeric and acts in conjunction with sigmaK as an activator or a repressor modulating the expression of various genes in particular those encoding the spore-coat. These LuxR family regulators may share a similar organization of their target binding sites. For example the LuxR dimer binds the lux box, a 20bp inverted repeat, GerE dimers bind two 12bp consensus sequences in inverted orientation having the central four bases overlap, and the NarL dimer binds two 7bp inverted repeats separated by 2 bp.
Pssm-ID: 99777 [Multi-domain] Cd Length: 57 Bit Score: 57.16 E-value: 1.64e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1906722815 921 LTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGL 971
Cdd:cd06170 1 LTPREREVLRLLAEGKTNKEIADILGISEKTVKTHLRNIMRKLGVKSRTQL 51
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
508-992 |
3.50e-10 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 64.51 E-value: 3.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 508 VLTALIGAMVRTGQVPRAVELLRIRRAEAVAAGEGPAGAHVL---------------------------EAHLLLTSNTS 560
Cdd:COG3321 802 VLTGLVRQCLAAAGDAVVLPSLRRGEDELAQLLTALAQLWVAgvpvdwsalypgrgrrrvplptypfqrEDAAAALLAAA 881
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 561 HRAFRQVLDAASFGLDPAPDTAGGRALLAARAVISVSRLDGVAESLAAARAVLLHGTPPADAPATLGSAAAVLLYTDRPD 640
Cdd:COG3321 882 LAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEA 961
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 641 EAETALRRLLEGADVLDDWQHATLLALCADAYERQGALDRALAATADALRGAPAEQTDSCRALARAVRLQTLLDRDQVAE 720
Cdd:COG3321 962 GALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAA 1041
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 721 AAALAPCGPVPPLEDGWQWNELLAARGRLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKAC 800
Cdd:COG3321 1042 AAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALLLLALLAALALAAAA 1121
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 801 GELAEEAVDGARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVL 880
Cdd:COG3321 1122 AALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALLLAALL 1201
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 881 REALETAYALEAHQLYATARRALVATGARPRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAY 960
Cdd:COG3321 1202 AALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALAALALLAAAAGLAALAAAAAAA 1281
|
490 500 510
....*....|....*....|....*....|..
gi 1906722815 961 RKLGISGRRGLRAALAADDPTIRAPGDGEPVE 992
Cdd:COG3321 1282 AAALALAAAAAAAAAALAALLAAAAAAAAAAA 1313
|
|
| CsgD |
COG2771 |
DNA-binding transcriptional regulator, CsgD family [Transcription]; |
803-978 |
1.11e-09 |
|
DNA-binding transcriptional regulator, CsgD family [Transcription];
Pssm-ID: 442052 [Multi-domain] Cd Length: 188 Bit Score: 59.00 E-value: 1.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 803 LAEEAVDGARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVLRE 882
Cdd:COG2771 10 LLALLLLLLALLALLLLLLLAALLLLLALLLLAALLLLAAAAAALAAALAAALLLGLLLLLLIALLLLLLLLLALLLLLA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 883 ALETAYALEAHQLYATARRALVATGARPRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRK 962
Cdd:COG2771 90 LLALLAALLARLAALLLALALAALLLAALARLLARAPGLTPREREVLRLLAEGLTLKEIARILGISERTVRTHLKRIYRK 169
|
170
....*....|....*.
gi 1906722815 963 LGISGRRGLRAALAAD 978
Cdd:COG2771 170 LGVSSRAELVALALRL 185
|
|
| COG3903 |
COG3903 |
Predicted ATPase [General function prediction only]; |
585-987 |
7.20e-08 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443109 [Multi-domain] Cd Length: 933 Bit Score: 56.56 E-value: 7.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 585 RALLAARAVISVSRLDGVAESLAAARAVLLHGTPPADAPATLGSAAAVLLYTDRPDEAETALRRLLEGADVLDDWQHATL 664
Cdd:COG3903 504 RAAAELRGPDQLAWLARLDAEHDNLRAALRWALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERALAAAGEAAAALA 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 665 LALCADAYERQGALDRALAATADALRGAPAEQTDSCRALARAVRLQTLLDRDQVAEAAALAPCGPVPPLEDGWQWNELLA 744
Cdd:COG3903 584 AAAALAAAAAAARAAAAAAAAAAAAAAAAAAAAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 663
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 745 ARGRLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKACGELAEEAVDGARRAQLPCALGAGL 824
Cdd:COG3903 664 AALAAAAAAAAAAAAAAAAAAAALAAAAAALAAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAA 743
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 825 ELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVLREALETAYALEAHQLYATARRALV 904
Cdd:COG3903 744 ALALAAAAAAAAAAAAAAALAAAAAAAALAALLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAA 823
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 905 ATGARPRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRGLRAALAADDPTIRA 984
Cdd:COG3903 824 AAAAAALAAALAAAAAAAAAAAAAAAAAAALAAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAA 903
|
...
gi 1906722815 985 PGD 987
Cdd:COG3903 904 ALA 906
|
|
| MalT |
COG2909 |
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription]; |
811-975 |
1.55e-06 |
|
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription];
Pssm-ID: 442153 [Multi-domain] Cd Length: 184 Bit Score: 49.70 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 811 ARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRiarGRAlYVSGRTEAARTVLREALETAYAL 890
Cdd:COG2909 31 ASRTDPLARLRARLELRADDLRREEAAALLRRRLLPLSEEDAARLAERTE---GWA-RLALDPEEALALLERLLALAEAA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 891 EAHQLYATARRALvatgarprrpvSRGPAALTPGElqvARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGRRG 970
Cdd:COG2909 107 GRLLLRALALRAL-----------GDREEALAALR---RRLLAEGLSNKEIAERLFISVNTVKTHLRNIYRKLGVRSRTE 172
|
....*
gi 1906722815 971 LRAAL 975
Cdd:COG2909 173 AVARA 177
|
|
| FixJ |
COG4566 |
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal ... |
879-966 |
1.94e-06 |
|
DNA-binding response regulator, FixJ family, consists of REC and HTH domains [Signal transduction mechanisms, Transcription];
Pssm-ID: 443623 [Multi-domain] Cd Length: 196 Bit Score: 49.33 E-value: 1.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 879 VLREALETAYALEAHQLYATARRALVATGArprrpvsrgpAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTS 958
Cdd:COG4566 106 ALLDAVRRALARDRARRAERARRAELRARL----------ASLTPREREVLDLVVAGLSNKQIARELGISPRTVEVHRAN 175
|
....*...
gi 1906722815 959 AYRKLGIS 966
Cdd:COG4566 176 VMEKLGAR 183
|
|
| PRK10651 |
PRK10651 |
transcriptional regulator NarL; Provisional |
875-968 |
1.54e-05 |
|
transcriptional regulator NarL; Provisional
Pssm-ID: 182619 [Multi-domain] Cd Length: 216 Bit Score: 47.33 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 875 AARTVLREALEtayaleahQLYATARRAlvatgarPRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVET 954
Cdd:PRK10651 125 AGEMVLSEALT--------PVLAASLRA-------NRATTERDVNQLTPRERDILKLIAQGLPNKMIARRLDITESTVKV 189
|
90
....*....|....
gi 1906722815 955 HLTSAYRKLGISGR 968
Cdd:PRK10651 190 HVKHMLKKMKLKSR 203
|
|
| EntF |
COG1020 |
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ... |
177-599 |
3.83e-05 |
|
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440643 [Multi-domain] Cd Length: 1329 Bit Score: 47.93 E-value: 3.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 177 RPGPVLLVVDDAEQADAASLRFLAHTARRLSGMPVLLAVsrcpetdAPLLDEMATRPLSSVLRLRPLTERGIGLIARRLT 256
Cdd:COG1020 909 APGDKRLVAYVVPEAGAAAAAALLRLALALLLPPYMVPA-------AVVLLLPLPLTGNGKLDRLALPAPAAAAAAAAAA 981
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 257 GRSGDQEFLAACLSATNGIPLLVTRLLAALHREGSPLTAAGIARAHLEDVALFGRRVVATLHQQPVALRAAQAMAVLGDG 336
Cdd:COG1020 982 PPAEEEEEEAALALLLLLVVVVGDDDFFFFGGGLGLLLLLALARAARLLLLLLLLLLLFLAAAAAAAAAAAAAAAAAAAA 1061
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 337 APFAHCAALALLDPAVFTRAVLTLDALGLVSSPPGTEDWYFAHPPTRETVLADMSPQLLMSTHLRAARLLHDGGAPAEQV 416
Cdd:COG1020 1062 PLAAAAAPLPLPPLLLSLLALLLALLLLLALLALLALLLLLLLLLLLLALLLLLALLLALLAALRARRAVRQEGPRLRLL 1141
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 417 AEHLRASGTTTTEPWARTVLREAARTASRRGAHEHAVELLRHCVPEDADSVDDPALMVELGLSEVRSDPEAGIGRLLRAL 496
Cdd:COG1020 1142 VALAAALALAALLALLLAAAAAAAELLAAAALLLLLALLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 1221
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 497 PLLTAPDRRLTVLTALIGAMVRTGQVPRAVELLRIRRAEAVAAGEGPAGAHVLEAHLLLTSNTSHRAFRQVLDAASFGLD 576
Cdd:COG1020 1222 LLLAAAAAALLALALLLALLALAALLALAALAALAAALLALALALLALALLLLALALLLPALARARAARTARALALLLLL 1301
|
410 420
....*....|....*....|...
gi 1906722815 577 PAPDTAGGRALLAARAVISVSRL 599
Cdd:COG1020 1302 ALLLLLALALALLLLLLLLLALL 1324
|
|
| COG3903 |
COG3903 |
Predicted ATPase [General function prediction only]; |
270-667 |
3.88e-05 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443109 [Multi-domain] Cd Length: 933 Bit Score: 47.70 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 270 SATNGIPLLVTRLLAALHREGSPLTAAGIARAHLEDV-ALFGRRVVATLHQQPVALRAAQAMAVLGDGAPFAHCAALALL 348
Cdd:COG3903 535 ALAHGDAELALRLAAALAPFWFLRGLLREGRRWLERAlAAAGEAAAALAAAAALAAAAAAARAAAAAAAAAAAAAAAAAA 614
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 349 DPAVFTRAVLTLDALGLVSSPPGTEDWYFAHPPTRETVLADMSPQLLMSTHLRAARLLHDGGAPAEQVAEHLRASGTTTT 428
Cdd:COG3903 615 AAAAAAAALLLLAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAALAAAAAAL 694
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 429 EPWARTVLREAARTASRRGAHEHAVELLRHCVPEDADSVDDPALMVELGLSEVRSDPEAGIGRLLRALPLLTAPDRRLTV 508
Cdd:COG3903 695 AAAAAAAALAAAAAAALAAAAAAAAAAAAAAALLAAAAAAALAAAAAAAALALAAAAAAAAAAAAAAALAAAAAAAALAA 774
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 509 LTALIGAMVRTGQVPRAVELLRIRRAEAVAAGEGPAGAHVLEAHLLLTSNTSHRAFRQVLDAASFGLDPAPDTAGGRALL 588
Cdd:COG3903 775 LLLALAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAALAAALAAAAAAAAAAAAAAAAAAAL 854
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1906722815 589 AARAVISVSRLDGVAESLAAARAVLLHGTPPADAPATLGSAAAVLLYTDRPDEAETALRRLLEGADVLDDWQHATLLAL 667
Cdd:COG3903 855 AAALAAAAAAAAAAALAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAALAAAAAAAAAAALAAAAAAAAAAAAAAAA 933
|
|
| PRK15369 |
PRK15369 |
two component system response regulator; |
918-963 |
5.77e-05 |
|
two component system response regulator;
Pssm-ID: 185267 [Multi-domain] Cd Length: 211 Bit Score: 45.45 E-value: 5.77e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 1906722815 918 PAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKL 963
Cdd:PRK15369 147 PPLLTPRERQILKLITEGYTNRDIAEQLSISIKTVETHRLNMMRKL 192
|
|
| PRK10100 |
PRK10100 |
transcriptional regulator CsgD; |
919-968 |
1.95e-04 |
|
transcriptional regulator CsgD;
Pssm-ID: 182241 [Multi-domain] Cd Length: 216 Bit Score: 43.71 E-value: 1.95e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1906722815 919 AALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGR 968
Cdd:PRK10100 154 ALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNR 203
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
633-897 |
2.27e-04 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 44.33 E-value: 2.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 633 LLYTDRPDEAETALRRLLEgadvLDDWQHATLLALcADAYERQGALDRALAATADALRGAPaEQTDSCRALARAVRLQTL 712
Cdd:COG2956 18 YLLNGQPDKAIDLLEEALE----LDPETVEAHLAL-GNLYRRRGEYDRAIRIHQKLLERDP-DRAEALLELAQDYLKAGL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 713 LDR--DQVAEAAALAPCGPvppledgwqwnELLAARGRLRLAEGDAPAALVDLTEAgerqrawQRLSPAVSSWWYWAGRA 790
Cdd:COG2956 92 LDRaeELLEKLLELDPDDA-----------EALRLLAEIYEQEGDWEKAIEVLERL-------LKLGPENAHAYCELAEL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 791 YAVLGNMKACGELAEEAVD---GARRAQLpcALGaglELLAAARGEDGALPLLEEAeavLTATPARLAltrVRIARGRAL 867
Cdd:COG2956 154 YLEQGDYDEAIEALEKALKldpDCARALL--LLA---ELYLEQGDYEEAIAALERA---LEQDPDYLP---ALPRLAELY 222
|
250 260 270
....*....|....*....|....*....|
gi 1906722815 868 YVSGRTEAARTVLREALETAYALEAHQLYA 897
Cdd:COG2956 223 EKLGDPEEALELLRKALELDPSDDLLLALA 252
|
|
| PRK04841 |
PRK04841 |
HTH-type transcriptional regulator MalT; |
920-968 |
1.11e-03 |
|
HTH-type transcriptional regulator MalT;
Pssm-ID: 235315 [Multi-domain] Cd Length: 903 Bit Score: 43.01 E-value: 1.11e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1906722815 920 ALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYRKLGISGR 968
Cdd:PRK04841 838 PLTQREWQVLGLIYSGYSNEQIAGELDVAATTIKTHIRNLYQKLGIAHR 886
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
428-860 |
1.94e-03 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 42.10 E-value: 1.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 428 TEPWARTVLREAARTASRRGAHEHAVELLRHCVPEDADSVDDPALMVELGLSEVRSDPEAGIGRLLRALPLLTAPDRRLT 507
Cdd:COG5635 503 EDPRWREVLLLLAGLLDDVKQIKELIDALLARDDAAALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLL 582
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 508 VLTALIGAMVRTGQVPRAVELLRIRRAEAVAAGEGPAGAHVLEAHLLLTSNTSHRAFRQVLDAASFGLDPAPDTAGGRAL 587
Cdd:COG5635 583 LLLLALLLALLALDLGLAALLLLLLLLLLLLLLLALALLLALLLLLLLLLLAELLLLALLALVLLSLLLASRLLLITLLL 662
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 588 LAARAVISVSRLDGVAESLAAARAVLLHGTPPADAPATLGSAAAVLLYTDRPDEAETALRRLLEGADVLDDWQHATLLAL 667
Cdd:COG5635 663 LAAASAALLLLLLLLLAELLLALLALASLLLLLLLALALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLA 742
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 668 CADAYERQGALDRALAATADALRGAPAEQTDSCRALARAVRLQTLLDRDQVAEAAALAPCGPVPPLEDGWQWNELLAARG 747
Cdd:COG5635 743 LALLLAGALLLESSALLAVLLASLLLALLLLSLLLLLVLLLALALLASLLLALLLLILLLVLLGSLLLLRLLDDLALLLL 822
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 748 RLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKACGELAEEAVDGARRAQLPCALGAGLELL 827
Cdd:COG5635 823 LALAAARLLLSSLALVALELARASLGASLVLLALLLATLLLLLLLLLALALALLSLLSLSSLALLSLLGLLLALSLLALL 902
|
410 420 430
....*....|....*....|....*....|...
gi 1906722815 828 AAARGEDGALPLLEEAEAVLTATPARLALTRVR 860
Cdd:COG5635 903 LLSLSLALAALLLAAREALTLDRLLSLASLLLA 935
|
|
| TMPK |
cd01672 |
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ... |
67-116 |
2.04e-03 |
|
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).
Pssm-ID: 238835 Cd Length: 200 Bit Score: 40.71 E-value: 2.04e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1906722815 67 VEGQEGIGKTTLLRSLAELARAQGLRVLEARgERTGRQTPFAVAHALLHP 116
Cdd:cd01672 5 FEGIDGAGKTTLIELLAERLEARGYEVVLTR-EPGGTPIGEAIRELLLDP 53
|
|
| EntF |
COG1020 |
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites ... |
580-977 |
2.13e-03 |
|
EntF, seryl-AMP synthase component of non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 440643 [Multi-domain] Cd Length: 1329 Bit Score: 42.15 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 580 DTAGGRALLAARAVISVSRLDGVAESLAAARAVLLH------------------GTPPADAPATLGSAAAVLLYTDRPDE 641
Cdd:COG1020 907 EDAPGDKRLVAYVVPEAGAAAAAALLRLALALLLPPymvpaavvlllplpltgnGKLDRLALPAPAAAAAAAAAAPPAEE 986
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 642 AETALRRLLEGADVLDDWQHATLLALCADAYERQGALDRALAATADALRGAPAEQTDSCRALARAVRLQTLLDRDQVAEA 721
Cdd:COG1020 987 EEEEAALALLLLLVVVVGDDDFFFFGGGLGLLLLLALARAARLLLLLLLLLLLFLAAAAAAAAAAAAAAAAAAAAPLAAA 1066
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 722 AALAPCGPVPPLEDGWQWNELLAARGRLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKACG 801
Cdd:COG1020 1067 AAPLPLPPLLLSLLALLLALLLLLALLALLALLLLLLLLLLLLALLLLLALLLALLAALRARRAVRQEGPRLRLLVALAA 1146
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 802 ELAEEAVDGARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVLR 881
Cdd:COG1020 1147 ALALAALLALLLAAAAAAAELLAAAALLLLLALLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLAA 1226
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 882 EALETAYALEAHQLYATARRALVATGARPRRPVSRGPAALTPGELQVARLAAAGDSNVDISRTLFVTQRTVETHLTSAYR 961
Cdd:COG1020 1227 AAAALLALALLLALLALAALLALAALAALAAALLALALALLALALLLLALALLLPALARARAARTARALALLLLLALLLL 1306
|
410
....*....|....*.
gi 1906722815 962 KLGISGRRGLRAALAA 977
Cdd:COG1020 1307 LALALALLLLLLLLLA 1322
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
524-725 |
3.19e-03 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 41.52 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 524 RAVELLRIRRAEAVAAGEGPAGAHVLEAHLLLTSNTSHRAFRQVLDAASFGLDPAPDTAGGRALLAAR--AVISVSRLDG 601
Cdd:COG3914 14 AAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLelAALLLQALGR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 602 VAESLAAARAVLLHGTPPADAPATLGSAaavLLYTDRPDEAETALRRLLEgadvlDDWQHATLLALCADAYERQGALDRA 681
Cdd:COG3914 94 YEEALALYRRALALNPDNAEALFNLGNL---LLALGRLEEALAALRRALA-----LNPDFAEAYLNLGEALRRLGRLEEA 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1906722815 682 LAATADALRGAPaEQTDSCRALARAvrlqtLLDRDQVAEAAALA 725
Cdd:COG3914 166 IAALRRALELDP-DNAEALNNLGNA-----LQDLGRLEEAIAAY 203
|
|
| SPS1 |
COG0515 |
Serine/threonine protein kinase [Signal transduction mechanisms]; |
648-924 |
7.42e-03 |
|
Serine/threonine protein kinase [Signal transduction mechanisms];
Pssm-ID: 440281 [Multi-domain] Cd Length: 482 Bit Score: 40.00 E-value: 7.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 648 RLLEGADVLDDWQHATLLALCADAYERQGALDRALAATAD-ALRGAPAEQTDSCRALARAVRLQTLLDRDQVAEAAALAP 726
Cdd:COG0515 205 RPPFDGDSPAELLRAHLREPPPPPSELRPDLPPALDAIVLrALAKDPEERYQSAAELAAALRAVLRSLAAAAAAAAAAAA 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 727 CGPVPPLEDGWQWNELLAARGRLRLAEGDAPAALVDLTEAGERQRAWQRLSPAVSSWWYWAGRAYAVLGNMKACGELAEE 806
Cdd:COG0515 285 AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAAAAAAAAALAAAAAAAAAAAAAALLAAAAALAAAAAA 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1906722815 807 AVDGARRAQLPCALGAGLELLAAARGEDGALPLLEEAEAVLTATPARLALTRVRIARGRALYVSGRTEAARTVLREALET 886
Cdd:COG0515 365 AAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAAAARL 444
|
250 260 270
....*....|....*....|....*....|....*...
gi 1906722815 887 AYALEAHQLYATARRALVATGARPRRPVSRGPAALTPG 924
Cdd:COG0515 445 LAAAAAAAAAAAAAPLLAALLAAAALAAAAAAAALALA 482
|
|
| RecA-like_Thep1 |
cd19482 |
RecA-like domain of the nucleoside-triphosphatase THEP1 family; This family represents the ... |
65-102 |
7.65e-03 |
|
RecA-like domain of the nucleoside-triphosphatase THEP1 family; This family represents the THEP1 family ATPase domain. It includes nucleoside-triphosphatase THEP 1 from Aquifex aeolicus (aaTHEP1) a nucleoside-phosphatase, with activity towards ATP, GTP, CTP, TTP and UTP; and which may hydrolyze nucleoside diphosphates with lower efficiency. The catalytic function of aaTHEP1 remains unclear, it may be a DNA/RNA modifying enzyme. Human THEP1 (hsTHEP1) may have a general function in many human tissues, as it is widely expressed in most examined tissues (such as in brain, heart, lymph node, skin, pancreas); it is especially highly expressed in embryonic and various tumor tissues. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410890 [Multi-domain] Cd Length: 164 Bit Score: 38.35 E-value: 7.65e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1906722815 65 LLVEGQEGIGKTTLLRSLAELARAQGLRV-----LEAR--GERTG 102
Cdd:cd19482 1 IFITGPPGVGKTTLVLKVAELLKESGLKVggfytPEVRegGKRIG 45
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