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Conserved domains on  [gi|1926907368|ref|WP_193646390|]
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cell wall hydrolase [Bacillus cereus]

Protein Classification

cell wall hydrolase( domain architecture ID 11467324)

cell wall hydrolase similar to Bacillus proteins SleB and CwlJ, which are spore cortex-lytic enzymes involved in the depolymerization of cortex peptidoglycan during germination

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CwlJ COG3773
Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, ...
 4-131 5.61e-43

Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442987  Cd Length: 124  Bit Score: 138.00  E-value: 5.61e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1926907368   4 IPYNESDVDLLARLIRAEAEGEGRQGEQLVGCVVVNRVFCDCldFKqiRTVRDAVYQsPGGFEAVQYGYFYQRARESEKE 83
Cdd:COG3773     1 IAYSDSDLDLLARAIYAEARGEPYEGQVAVAAVVLNRVRSPR--FP--NTICGVVYQ-PGQFSPVCDGQINRPPEEEARR 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1926907368  84 IARRVLQGEWRWPARWALWYFRPVGACPPQWYNQPFAGQFKSHCFYEP 131
Cdd:COG3773    76 AARDALNGWRRDPTGGALYFHNPATVTPSWARSRPKTARIGNHVFYRP 123
 
Name Accession Description Interval E-value
CwlJ COG3773
Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, ...
 4-131 5.61e-43

Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442987  Cd Length: 124  Bit Score: 138.00  E-value: 5.61e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1926907368   4 IPYNESDVDLLARLIRAEAEGEGRQGEQLVGCVVVNRVFCDCldFKqiRTVRDAVYQsPGGFEAVQYGYFYQRARESEKE 83
Cdd:COG3773     1 IAYSDSDLDLLARAIYAEARGEPYEGQVAVAAVVLNRVRSPR--FP--NTICGVVYQ-PGQFSPVCDGQINRPPEEEARR 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1926907368  84 IARRVLQGEWRWPARWALWYFRPVGACPPQWYNQPFAGQFKSHCFYEP 131
Cdd:COG3773    76 AARDALNGWRRDPTGGALYFHNPATVTPSWARSRPKTARIGNHVFYRP 123
Hydrolase_2 pfam07486
Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most ...
 24-129 1.68e-21

Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance Swiss:P50739 is expressed during sporulation as an inactive form and then deposited on the cell outer cortex. During germination the the enzyme is activated and hydrolyses the cortex. A similar role is carried out by the partially redundant Swiss:P42249. It is not clear whether these enzymes are amidases or peptidases.


Pssm-ID: 462179  Cd Length: 101  Bit Score: 82.57  E-value: 1.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1926907368  24 GEGRQGEQLVGCVVVNRVFcDClDFKQirTVRDAVYQsPGGFEAVQYGYFYQRARESEKEIARRVLQGeWRWPARWALWY 103
Cdd:pfam07486   1 GEPYEGQVAVANVILNRVR-SP-RFPN--TICGVVYQ-PGQFSPVCDGRINLPPSEEAIRAARDALAG-ERDPTGGALYF 74

                          90       100
                  ....*....|....*....|....*...
gi 1926907368 104 FRPVGAcPPQWYNQ--PFAGQFKSHCFY 129
Cdd:pfam07486  75 HNPSVA-PSSWIWSrgVRTARIGNHVFY 101
 
Name Accession Description Interval E-value
CwlJ COG3773
Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, ...
 4-131 5.61e-43

Cell wall hydrolase CwlJ, involved in spore germination [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442987  Cd Length: 124  Bit Score: 138.00  E-value: 5.61e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1926907368   4 IPYNESDVDLLARLIRAEAEGEGRQGEQLVGCVVVNRVFCDCldFKqiRTVRDAVYQsPGGFEAVQYGYFYQRARESEKE 83
Cdd:COG3773     1 IAYSDSDLDLLARAIYAEARGEPYEGQVAVAAVVLNRVRSPR--FP--NTICGVVYQ-PGQFSPVCDGQINRPPEEEARR 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1926907368  84 IARRVLQGEWRWPARWALWYFRPVGACPPQWYNQPFAGQFKSHCFYEP 131
Cdd:COG3773    76 AARDALNGWRRDPTGGALYFHNPATVTPSWARSRPKTARIGNHVFYRP 123
Hydrolase_2 pfam07486
Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most ...
 24-129 1.68e-21

Cell Wall Hydrolase; These enzymes have been implicated in cell wall hydrolysis, most extensively in Bacillus subtilis. For instance Swiss:P50739 is expressed during sporulation as an inactive form and then deposited on the cell outer cortex. During germination the the enzyme is activated and hydrolyses the cortex. A similar role is carried out by the partially redundant Swiss:P42249. It is not clear whether these enzymes are amidases or peptidases.


Pssm-ID: 462179  Cd Length: 101  Bit Score: 82.57  E-value: 1.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1926907368  24 GEGRQGEQLVGCVVVNRVFcDClDFKQirTVRDAVYQsPGGFEAVQYGYFYQRARESEKEIARRVLQGeWRWPARWALWY 103
Cdd:pfam07486   1 GEPYEGQVAVANVILNRVR-SP-RFPN--TICGVVYQ-PGQFSPVCDGRINLPPSEEAIRAARDALAG-ERDPTGGALYF 74

                          90       100
                  ....*....|....*....|....*...
gi 1926907368 104 FRPVGAcPPQWYNQ--PFAGQFKSHCFY 129
Cdd:pfam07486  75 HNPSVA-PSSWIWSrgVRTARIGNHVFY 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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