|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
18-442 |
1.29e-151 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 437.38 E-value: 1.29e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 18 MHKKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLG 97
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHLGSAAYLGAVALGTTIFNTLFWLFGFLRMGTTGLVAQALGAGDREEAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 98 LVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVI 177
Cdd:cd13136 81 ALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 178 ITNITNIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFGLICVYRIWAKKQLPSPWDLLKKtsHGLSRFVKLNRDIFLRS 257
Cdd:cd13136 161 VGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSRRLPSK--AALKRLFKLNRDIFIRT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 258 LCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVL 337
Cdd:cd13136 239 LALLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLGVLL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 338 TIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGKDMRNSMFVATCCFFVIFFLA-SSL 416
Cdd:cd13136 319 ALLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLPLLFLLvPLW 398
|
410 420
....*....|....*....|....*.
gi 1938527557 417 ENHALWLAMLSFMAMRGIGLGVLFVS 442
Cdd:cd13136 399 GNHGLWLALILFMLLRGLTLALRLPR 424
|
|
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
20-451 |
4.74e-126 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 372.92 E-value: 4.74e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:PRK10367 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:PRK10367 89 LVQPLLLALGAGALIALLRTPLIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFGLICVYRIWAKKQLPSPwdLLKKTSHG-LSRFVKLNRDIFLRSL 258
Cdd:PRK10367 169 NILNIVLDLWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKVLKLRGISLE--MLKTAWRGnFRRLLALNRDIMLRSL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 259 CLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVLT 338
Cdd:PRK10367 247 LLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFS 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 339 IVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGKDMRNSMFVATCCFFVIFFLASSLEN 418
Cdd:PRK10367 327 LVYALAGEHIIALLTSLPQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLPWLGN 406
|
410 420 430
....*....|....*....|....*....|...
gi 1938527557 419 HALWLAMLSFMAMRGIGLGVLFVSQWKKGEFLA 451
Cdd:PRK10367 407 HGLWLALTVFLALRGLSLAAIWRRHWRNGTWFA 439
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
13-439 |
1.98e-86 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 270.48 E-value: 1.98e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 13 LSNQAMHKKVLLLAIPMVLSNITVPLLGLVDAAVIGHLeHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGAND 92
Cdd:COG0534 1 LTEGPILKLLLRLALPIILGNLLQSLYGLVDTIFVGRL-GTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 93 GKQLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAP 172
Cdd:COG0534 80 REEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 173 MWVVIITNITNIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFGLICVYRiwAKKQLPSPWDLLKKTSHGLSRFVKLNRD 252
Cdd:COG0534 160 MIIMLIGNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFR--KRSLLRLRLRDLRPDRKILKRILRIGLP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 253 IFLRSLCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFN 332
Cdd:COG0534 238 AGLQQLAESLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 333 ICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGKDMRNSMFVATCCFFVIFFL 412
Cdd:COG0534 318 IGLLLALLLFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAY 397
|
410 420 430
....*....|....*....|....*....|
gi 1938527557 413 ASS---LENHALWLAMLSFMAMRGIGLGVL 439
Cdd:COG0534 398 LLAflgLGLTGVWLALPIGEVLRALLLLLR 427
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
28-370 |
1.64e-49 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 171.66 E-value: 1.64e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 28 PMVLSNITVPLLGLVDAAVIGHLEHSwYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLVFVQGVTMA 107
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHLGPV-DLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 108 LGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIITNITNIVLD 187
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 188 IVFVIGL--GWQVEGAAFASVMADYAGLTFGLICVYRiwaKKQLPSPWDLLKKTSHG-LSRFVKLNRDIFLRSLCLQATF 264
Cdd:TIGR00797 160 YILIFGKfgFLGIVGAALATVISYWLMFLLLLYYIKK---AKKIGLKWEGLLKPDWEvLKRLLKLGLPIAFRVILESLSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 265 TFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVLTIVFAIA 344
Cdd:TIGR00797 237 ALLALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILF 316
|
330 340
....*....|....*....|....*.
gi 1938527557 345 GSSLINMITTIPDVKSQAEVYLPWLI 370
Cdd:TIGR00797 317 REFIARLFTNDPEVLELAAIYLIFVA 342
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
20-447 |
4.24e-41 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 151.53 E-value: 4.24e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLehswylGGVALGGTMI-SVTFWLLGFLRMSTTG----LAAQSYGANDGK 94
Cdd:cd13133 5 REILKIALPLVLSMLSQTVMGFTDRAFLGRL------SEVALAASGPaGVLYFAILMLFFGLSSgvqvFVAQYNGAGRYS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 95 QLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMW 174
Cdd:cd13133 79 RIGRVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 175 VVIITNITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLTFGLICVYRiwakkqlpspwdLLKKTSHGLSRFVKLN 250
Cdd:cd13133 159 ANLVMVVVNIVLDYALIFGKLgfpaMGIAGAAIATVIAEAVSLLFFLLLLFR------------RKNRRRFGLRRAWRFD 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 251 RDIFLR-----------SLCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDEL 319
Cdd:cd13133 227 RELLRRilrlglpsglqFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 320 NQSLIGTFFWSFNICLVLTIVFAIAGSSLINMITTIPDVkSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGK-DMRNS 398
Cdd:cd13133 307 MRVTRRGLKLALAYMLLLGILFLLFPELLLSIFTPGADF-ALIAELAVPLLRFVAAYILFDALALVFAGALRGAgDTRFV 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1938527557 399 MFVATCCFFVIFFLASSLEN------HALWLAMLSFMAMrgigLGVLFVSQWKKG 447
Cdd:cd13133 386 MLAELIVAWLYLLPPAYLLVvlgaglAGAWTVETVYVIV----LALIFLLRFRSG 436
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
20-445 |
1.78e-39 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 147.27 E-value: 1.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSwYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRLGAE-AIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd13137 80 LGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIGL----GWQVEGAAFASVMADYAGLTFGLICVYRIWAKKQLPSPWDLLKKtsHGLSRFVKLNRDIFL 255
Cdd:cd13137 160 NVLNIVLDYVLIFGLwgfpGLGVAGAALATVISRVVGALLLLFLLLRGRLPIKISFKGFRLDR--KIIKKLLRIGLPAGL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 256 RSLCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICL 335
Cdd:cd13137 238 EQLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 336 VLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGAtkgKDMRNSMFVATCCFFV------- 408
Cdd:cd13137 318 LLGLLLFIFAPPLASLFTPDPEVIELGVLYLRIVALSQPFLAISFVLSGALRGA---GDTRPPLIINLISMWLvrlplay 394
|
410 420 430
....*....|....*....|....*....|....*...
gi 1938527557 409 IFFLASSLENHALWLAMLSFMAMRGIGLGVLFVS-QWK 445
Cdd:cd13137 395 LLGFVLGLGLTGIWLAMFVDTIVRAILLLYRFRKgKWK 432
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
26-440 |
6.33e-38 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 142.85 E-value: 6.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 26 AIPMVLSNITVPLLGLVDAAVIGHLEHSWYlGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLVFVQGVT 105
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLGDAL-AAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 106 MALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIITNITNIV 185
Cdd:cd12082 80 LAILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNIL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 186 LDIVFVIGLG---WQVEGAAFASVMADYAGLTFGLICVyrIWAKKQLPSPWDLLKKTSHGLSRFVKLNRDIFLRSLCLQA 262
Cdd:cd12082 160 LDPLLIFGLGppeLGIAGAALATVISYVIGALLLLIYL--RKGKKILKFKLSLLKPDLELLRRLLRIGLPSAIQNSLLSL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 263 TFTFMTFQGASF-GDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVLTIVF 341
Cdd:cd12082 238 GLLIIVAIVAAFgGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 342 AIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGAtkgKDMRNSMFVATCCFFVIFFLAS------S 415
Cdd:cd12082 318 LLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAA---GRTLKSLIVSLLSYWVVRLPLAyvlaylG 394
|
410 420
....*....|....*....|....*
gi 1938527557 416 LENHALWLAMLSFMAMRGIGLGVLF 440
Cdd:cd12082 395 LGLYGIWLALVISLILAALVLLLFF 419
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
20-445 |
4.80e-37 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 140.29 E-value: 4.80e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13138 3 KTLLLFALPLLLSNLLQQLYNLVDLLIVGQFLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd13138 83 VGTLLVLFLILGIVLTILGLLFAPPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVIIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFGLICVYRiwAKKQLPSPWDLLKKTSHGLSRFVKLNRDIFLRSLC 259
Cdd:cd13138 163 CVLNIILDLLFIAVFHMGVAGAALATVIAQAISVLLALYYLRK--KKLPFKLSLKDFRFDKEILKEILKIGLPSALQQSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 260 LQATFTFMTFQGASFGDDVVAANAV---LMSFLMIIsygMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLV 336
Cdd:cd13138 241 VSISFLIINSIVNSYGVVASAAYGIankINSFAFLP---PSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 337 LTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGKDMRNSMFVATCCFFVIF-FLASS 415
Cdd:cd13138 318 IILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLaYLLSR 397
|
410 420 430
....*....|....*....|....*....|....
gi 1938527557 416 LENH---ALWLAML-SFMAMRGIGLGVLFVSQWK 445
Cdd:cd13138 398 LTGLglfGIWLAMPiSNILSAIICIIYYRKGRWK 431
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
20-389 |
4.92e-33 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 129.54 E-value: 4.92e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSwYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13134 3 LSLFALAWPIFIELLLQMLLGTIDTFMLSRYSDN-AVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd13134 82 AGVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLIM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLTFGLICVYRiwAKKQLPSPWDLLKKTSHGLSRFVKLNRDIFL 255
Cdd:cd13134 162 NILNIVGNYLLIFGWFglpkLGVAGVAISTVISRAVGLVLLFILLFR--KLKIRFRLKDLRPFPKKLLKKILKIGLPSAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 256 RSLCLQATFTFMTFQGASFGDDVVAANA---VLMSFLMIISYGMdgfAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFN 332
Cdd:cd13134 240 EELSYNLSQTVITAFIARLGTAALAARTyasNISMFVFLFSLAI---GQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLL 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1938527557 333 ICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGA 389
Cdd:cd13134 317 VSLAVALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNIVLIGSLRAA 373
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
20-440 |
6.34e-32 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 126.09 E-value: 6.34e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHlehswYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSY-----GANDGK 94
Cdd:cd13143 4 KLFLKFALPAIIGMLVNGLYNIVDGIFVGH-----GVGALALAAVNLVFPIIMLLMALGLMIGVGGASLisrrlGAGDRE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 95 QLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMW 174
Cdd:cd13143 79 KANRIFSTALLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAML 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 175 VVIITNITNIVLDIVFVIGLGWQVEGAAFASVMADYAGltFGLICVYRIWAKKQLPSPWDLLKKTSHGLSRFVKLNRDIF 254
Cdd:cd13143 159 GMLIGAVLNIILDPLFIFVLGLGIAGAALATVIAQLIS--LLLLLLYFFRGKSLLKLSLLRFKLSLKIIKEILALGFPSF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 255 LRSLCLQATFTFMTFQGASF-GDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNI 333
Cdd:cd13143 237 LMQLSSSVVTIVLNLTLLGYgGDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 334 CLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGKdmrNSMFVA---TCCFFV-- 408
Cdd:cd13143 317 GLVLFLILLLFPEQIVSLFTDDPELIALAARILRIFLLAFPLAGINIVLSGYFQAIGKAK---RAALLSllrQGLFLIpl 393
|
410 420 430
....*....|....*....|....*....|...
gi 1938527557 409 IFFLASSLENHALWLAM-LSFMAMRGIGLGVLF 440
Cdd:cd13143 394 LLILPRLFGLDGIWLAFpLAEILTLLLALILLK 426
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
20-446 |
7.12e-26 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 109.13 E-value: 7.12e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEhSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRLG-ADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLhSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd13131 82 VRQGLWLALLLSLPLMLL-LWLAPPILPLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIG------LGwqVEGAAFASVMADYAGLTFGLICV--------YRIWAKKQLPSpWDLLKKtshglsr 245
Cdd:cd13131 161 LVLNIPLNYVLIFGkfglpaLG--GAGAGLATAIVYWLMFLALAFYIrrhkrfrrYRLFARFWRPD-WARLKE------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 246 FVKLNRDIFLRSLCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIG 325
Cdd:cd13131 231 LLRLGLPIGLTIFFEVSLFAAVALLMGRLGTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDPADARRAGLV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 326 TFFWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLpwliampLVSMWCFLLDGIFV---GATKG-KDMRNSMFV 401
Cdd:cd13131 311 GLGLGVGFAALTALLLLLFPEQIAGLYTNDPAVIALAASLL-------VFAALFQLFDGIQVvaaGALRGyKDTRVPFLL 383
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1938527557 402 ATCCFFVI-FFLASSLENHA------LWLAMLSFMAMRGIGLGVLFVSQWKK 446
Cdd:cd13131 384 ALISYWGIgLPLGYLLAFTTglgafgVWIGLIIGLALAAILLLWRFRRLQRR 435
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
20-366 |
4.99e-25 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 106.93 E-value: 4.99e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSwYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13139 14 RAIFLLAIPMVLEMVMESLFAVVDLYFVSRLGAL-AIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEGAGFA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd13139 93 AVQAILLGVALSLILSILGYFFAEDILSLMGASPAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAMRSLWLA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLTFGLICVYRIW-----AKKQLPSPWDLLKKtshglsrFVKLN 250
Cdd:cd13139 173 NGLNIILDPLFIFGLGpipaMGVTGAAIATTIGRSIGVLYQLYHLFKGKgriqiRRRHLKLDWAIIKK-------IIKIA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 251 RDIFLRSLCLQATFTFMTFQGASFGDDVVAANAV---LMSFLMIISYGMdgfAYAMEAMVGKAIGAKDKDELNQSLIGTF 327
Cdd:cd13139 246 VGGILQFLIASSSWIFLVRIIAEFGSTALAGYTIairIIMFALLPAWGL---SNAAATLVGQNLGAGQPDRAEKSVWRAG 322
|
330 340 350
....*....|....*....|....*....|....*....
gi 1938527557 328 FWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYL 366
Cdd:cd13139 323 KYNMVFLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEAL 361
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
20-370 |
1.02e-22 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 99.67 E-value: 1.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEhSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRIS-IRYYSAVGNVTTPFNTITGFLGSISIGFTILGSQSVGAKDIKRINDY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd13135 80 AISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGIIK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIG-LGW---QVEGAAFASVMADYAGLTFGLICVYRIWAKKQLPSPWDLLKKTSHGLSRFVKLNRDIFL 255
Cdd:cd13135 160 NLLNVILDYVLIFGnFGFprlGIIGAAIATTIANVLNLIILVYLCRKIKKLTFKLSNTKVLKANIRPYKFTIKLGLPLGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 256 RSLCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICL 335
Cdd:cd13135 240 EEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGLLIYI 319
|
330 340 350
....*....|....*....|....*....|....*
gi 1938527557 336 VLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLI 370
Cdd:cd13135 320 AAAIVFLAFPYKILSLFTNDPELINYSIPYLIFII 354
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
13-446 |
2.69e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 95.72 E-value: 2.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 13 LSNQAMHKKVLLLAIPMVLSNITVPLLGLVDAAVIGHLehswylGGVALGGTMIS--VTFWLLGF---LRMSTTGLAAQS 87
Cdd:cd13142 4 ILEGSILRTLLKLAWPIIVSNLLQVAYNLADTFWLGRL------GADAVAAPSISwpLIFLFISLgggLTVAGTALVAQY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 88 YGANDGKQLGLVFVQGVTMALGFAGVF-LLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGT 166
Cdd:cd13142 78 TGAGDYDKANKVAGQTFSFVIILSLILaVLGYILSRPLLLLLIGAPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 167 QNAKAPMWVVIITNITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLTFGLICVYR------IWAKKQLPSpWDLL 236
Cdd:cd13142 158 GDTKTPMKIMFGSVLLNVILDPLLIFGIGpfpgLGVAGAALATVISRGIAAVIGLYLLFKgrvglkISLRDLKPD-WEWL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 237 KKTshglsrfVKLNRDIFLRSLCLQATFTFMTFQGASFGDDVVAANAV---LMSFLMIISYGMdgfAYAMEAMVGKAIGA 313
Cdd:cd13142 237 KKI-------FRIGLPSSIEQSARALGFTVMTALVAGFGTVVVAAYGIgnrIISLVFLPAFGL---ARATSTMVGQNLGA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 314 KDKDELNQSLIGTFFWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPwLIAMPLVSM-WCFLLDGIFVGATKg 392
Cdd:cd13142 307 GQIDRAEEIVKKAALLIFLILVIGGVLAFLFAEPIVRVFINDPEVIKEGADFLR-IVAPSFPFFgLFQVINGAFRGSGH- 384
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1938527557 393 kdMRNSMFVATCCFFVI-----FFLA--SSLENHALWLAM-LSFMAMRGIGLGVLFVSQWKK 446
Cdd:cd13142 385 --TLTAMIISILRLWVIriplaYLLAyvLGLGVTGIWIAMaISNIVAALIALAWFKRGTWKK 444
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
28-189 |
9.39e-19 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 83.00 E-value: 9.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 28 PMVLSNITVPLLGLVDAAVIGHLeHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLVFVQGVTMA 107
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHL-GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 108 LGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIITNITNIVLD 187
Cdd:pfam01554 80 LLLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLN 159
|
..
gi 1938527557 188 IV 189
Cdd:pfam01554 160 YL 161
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
19-369 |
1.73e-17 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 84.11 E-value: 1.73e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 19 HKKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSwylgGVALGGTmISVTFWLL-GFLRMSTTG---LAAQSYGANDGK 94
Cdd:cd13140 4 LKTLLRLALPIMGTSFIQMAYNLTDMFWVGRLGSD----AVAAVGT-AGFFVWLAyALALLSKIGaqvKVSQSIGAKDEK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 95 QLGLVFVQGVTMALGFAGVFLLLHSLVADL---VFSLSSASdqVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKA 171
Cdd:cd13140 79 EARKYARNALQLNLLLGILYGLLLLLFAKPligFFNLGDAE--VISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 172 PMWVVIITNITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLtfgLICVYRIWAKKQLPSPWDLLKKTS-HGLSRF 246
Cdd:cd13140 157 PFIINAIGLVLNIILDPLLIFGFGpfpaLGVAGAALATVLAQAIVF---LLFLYALKKKKGLFLKIRILKRPDrKYIKEI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 247 VKLNRDIFLRSlCLQATFT-FMTFQGASFGDDVVAANAVlMSFLMIISYGM-DGFAYAMEAMVGKAIGAKDKDELNQSLI 324
Cdd:cd13140 234 LKLGLPVALQS-ILFALISmILARIIASFGPVAIAAQKV-GSQIESISWMTaEGFSTALAAFVGQNYGAGKYDRIRKGYK 311
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1938527557 325 GTFFWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWL 369
Cdd:cd13140 312 TALKIASAIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRIL 356
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
21-440 |
4.08e-17 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 83.05 E-value: 4.08e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 21 KVLL-LAIPMVLSNITVPLLGLVDAAVIGHL-EHSwyLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGL 98
Cdd:cd13144 8 RLLLtMSIPAMISMLFQALYNIVDSIFVARLgENA--LTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 99 VFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVII 178
Cdd:cd13144 86 AANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIAQLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 179 TNITNIVLDIVFVIGL----GWQVEGAAFASVmadyAGLTFGLICVYRIWAKKQLPSPWDLlkKTSHGLSRFVKLNRDIF 254
Cdd:cd13144 166 GAIINIILDPILIFGLfgfpAMGIAGAAIATV----IGQILAMFLAFFFLLRKNKDVQPDL--RLFRPSLRIIKEIYAVG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 255 LRSLCLQATFTFMTFQG----ASFGDDVVAANAV---LMSFLMIISYGMDGfayAMEAMVGKAIGAKDKDELNQSLIGTF 327
Cdd:cd13144 240 LPSIIMQAISSVMVFGLnkilAGFGPTAVAVFGIyfkLQSFVFMPVFGLNN---GLIPIVAYNYGAGNKDRIREAIKYAI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 328 FWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGkdmRNSMFVATCCFF 407
Cdd:cd13144 317 LIAVVIMLAGGLLFQLFPDQLLGLFNASEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRG---VYSLIISVARQL 393
|
410 420 430
....*....|....*....|....*....|....*...
gi 1938527557 408 VI-----FFLASSLENHALWLAMLSFMAMRGIGLGVLF 440
Cdd:cd13144 394 VVllplaWLLAKMFGLNGVWWSFPIAEIVSFLLSLLFL 431
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
20-439 |
2.59e-16 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 80.69 E-value: 2.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEhSWYLGGVALGGTMISVT-FWLLGFLRMSTTGLAAQSYGANDGKQLGL 98
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLG-KLELAAASLASSFANVTgFSILLGLASALDTLCGQAFGAKNYKLVGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 99 VFVQGVTMALGFAGVFLLLHsLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVII 178
Cdd:cd13132 82 YLQRALVILLLCCVPISLLW-LNTEPILLLLGQDPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVYISLV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 179 TNITNIVLDIVFVIGLGWQVEGAAFASVMADYagLTFGLICVYRIWAKKQLPSPWDLLKKTSHGLSRFVKLNRDIFLrSL 258
Cdd:cd13132 161 ALLLNILLNYLLVFVLGLGFIGAALATSISYW--LIVVLLLLYIFFSKGHKATWGGFSREAFRGWGPFLKLAIPSAL-ML 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 259 CLQA-TFTFMTFQGASFGDDV-VAANAVLM---SFLMIISYgmdGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNI 333
Cdd:cd13132 238 CLEWwAFEILVLLAGLLPGTVaLAAQSICLtttSLLYMIPL---GISIAASVRVGNELGAGNPKRAKLAAIVALILSLVI 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 334 CLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGAtkGKDMRnSMFVATCCFFVI---- 409
Cdd:cd13132 315 GVVVAILLLVLRDVWAYLFTSDEEVIALVADLLPILALFQIFDGLQAVLSGVLRGC--GRQKL-GAYVNLVAYYLIglpv 391
|
410 420 430
....*....|....*....|....*....|...
gi 1938527557 410 -FFLA--SSLENHALWLAMLSFMAMRGIGLGVL 439
Cdd:cd13132 392 gLLLAfvLGLGLKGLWIGLIAGLILQAVILLLI 424
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
20-369 |
1.40e-15 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 78.50 E-value: 1.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLehswylGGVALGGtmISVTFWLLGFLRMSTTGLA-------AQSYGAND 92
Cdd:cd13149 9 RHLIKLTLPMIFGILAMLIFNLTDTFFVGKL------GTKELAA--ISFTFPVVLFLNSLTIGLGigasaviSRAIGAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 93 GKQLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAP 172
Cdd:cd13149 81 RNKAKRLATDSLILSLLLSVIVSLLGLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 173 MWVVIITNITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLTFGLicvYRIWAKKQLPSPWDLLKK-TSHGLSRFV 247
Cdd:cd13149 161 SLVMLGAALVNVILDPILIFGFGpipgMGIAGAAIATVISRALGLGAAL---YFLHYHHRLIDFSEPSLKaLFRSWKDIL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 248 KLNRDIFLRSLCLQATFTFMTFQGASFGDDVVAANAV---LMSFLMIISYGMDGfayAMEAMVGKAIGAKDKDELNQSLI 324
Cdd:cd13149 238 SIGIPAALSNILTPLSAAFITALVATYGPAAVAAFGVatrIESFAFIIVMALSS---ALGPFVGQNWGAGQYERVQEGLK 314
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1938527557 325 GTFFWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWL 369
Cdd:cd13149 315 ISLKFSLIYGAILGIVLALFAGWLASLFSAEPEVIELITLYLLIV 359
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
25-376 |
7.88e-13 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 69.74 E-value: 7.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 25 LAIPMVLSNITVPLLGLVDAAVIGHL--EHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLVFVQ 102
Cdd:cd13146 13 LALPILIGQLFQLLYNITDTIWISMIdpSDPALVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGAQRAKELDQAADS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 103 GVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIITNIT 182
Cdd:cd13146 93 GLALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMMAMLIGTVV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 183 NIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFgLICVYRIwAKKQLPSPWDLLKKTSHGLSRFVKLNRDIFLRSLCLQA 262
Cdd:cd13146 173 NIVLDPILIFVFDMGVKGAALATVLAQAISLLY-LLYVFLI-GKSNVTIHIKLSNISSSVIVEILRVGLPQMLLQLISSI 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 263 TFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVLTIVFA 342
Cdd:cd13146 251 SFLIYNRIIIDIDPVAMTAFTLVGRLDQFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVILGIVVVLVLVLGYV 330
|
330 340 350
....*....|....*....|....*....|....*
gi 1938527557 343 IAGSSLINMITTIPDVKSQAEVYLPWL-IAMPLVS 376
Cdd:cd13146 331 LVAPWLFSLFTTVPEVVAYAVLQVRTMaLALPFVA 365
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
20-368 |
2.02e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 68.50 E-value: 2.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLeHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd13141 11 KHIISMALPIAIGMIIQTLYFLVDLYFVGQL-GDAALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRKDQGEANAV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSiraWSAPAALTNFVILGW---LLGTQNAKAPMWVV 176
Cdd:cd13141 90 FNQSLLLAAVLGLVVLVLGYLFGRLYLETLAADAATVEAATTYLY---WFIPSLALQFILTVLgaaLRGTGIVKPFMVIQ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 177 IITNITNIVLDIVFVIGLG----WQVEGAAFASVMADYAGLTfgLICVYRIWAKKQLPSPWDLLKktshglsrfvkLNRD 252
Cdd:cd13141 167 ILAVLLNIILAPILITGWGtgraLGVAGAGLASSISVAIAVV--LLLYYFLRLEKYLRLDLALWR-----------PDLP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 253 IFLRSLCLQ----ATFTFMTFQGAS-------FGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQ 321
Cdd:cd13141 234 TWKRLLKIGlpsgGEFLLTFVYMAViywalrpFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRE 313
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1938527557 322 SLIGTFFWSFNICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPW 368
Cdd:cd13141 314 TFRITAILTTALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRY 360
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
20-343 |
1.03e-10 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 63.33 E-value: 1.03e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAA-VIGhlehswyLGGVALG--GTMISVTFWLLGF---LRMSTTGLAAQSYGANDG 93
Cdd:cd13147 9 KAIIKLSIPMIIAMLLQTLYNLVDAIwVAG-------LGADALAaiGFVFPLFMIIIGLgngLGAGASSAISRRIGAKDK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 94 KQLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDqVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPM 173
Cdd:cd13147 82 EGADNAAVHSILLGLIISIILTIVLLPFLEPILVLMGAGE-VLDLAVDYGRIIFLGSIFLIFNNVAYGILRGEGDTKRAM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 174 WVVIITNITNIVLDIVFVIGLGWQVEGAAFASVMadyAGLTFGLICVYRIWAKKQLpspwdLLKKTSHGLSRFVKLNRDI 253
Cdd:cd13147 161 YAMVAGSILNIILDPIFIYTLGLGIAGAAWATVI---SMLISSLVLLYWFFVKKDT-----YVSLSLKNFKFDKKIVKDI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 254 F---LRSLCLQATFTFMTFQGASF-----GDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIG 325
Cdd:cd13147 233 LkvgIPASLEQLIMSVLMIILNLIlvivaGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLKTAYNY 312
|
330
....*....|....*...
gi 1938527557 326 TFFWSFNICLVLTIVFAI 343
Cdd:cd13147 313 SIKLGLIIELIIAILIFI 330
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
253-413 |
2.89e-10 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 58.73 E-value: 2.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 253 IFLRSLCLQATFTFMTFQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFN 332
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 333 ICLVLTIVFAIAGSSLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGAtkgKDMRNSMFVATCCFFVIFFL 412
Cdd:pfam01554 82 LSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQ---GDTKPPMYINIISLLLNIPL 158
|
.
gi 1938527557 413 A 413
Cdd:pfam01554 159 N 159
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
20-409 |
2.37e-08 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 55.97 E-value: 2.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEhSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:PRK01766 12 RQLLALALPILLAQVAQTAMGFVDTVMAGGVS-ATDLAAVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERIAHQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:PRK01766 91 VRQGLWLALFLSVLIMLVLYNAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGKTKPTMVIGFLG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 180 NITNIVLDIVFVIG------LGWQVEGAAFASVMADYAGLTFGLICV------YRIWAKKQLPSpWDLLKktshglsRFV 247
Cdd:PRK01766 171 LLINIPLNYIFIYGkfgfpeLGGVGCGVATAIVYWVMFLAMLIYIKRarrfrdFRLFKGLYKPD-WAVIK-------RLL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 248 KLNRDIFLRSLCLQATFTFMTFQGASFGDDVVAANAVLMSF----LMI-ISYGMdgfayAMEAMVGKAIGAKDKDELNQ- 321
Cdd:PRK01766 243 KLGLPIGLAIFFEVSLFAVVTLLVSPLGTVTVAAHQIALNFssllFMLpLSLAM-----ALTIRVGFELGAGRTLDARQy 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 322 SLIG-TFFWSFNICLVLTIVF---AIAGsslinMITTIPDVKSQAEVYLpwliampLVSMWCFLLDGIFV---GATKG-K 393
Cdd:PRK01766 318 AYIGlAVGLGMALLTAIFLVLfreQIAL-----LYTDDPEVVALASHLL-------LFAALFQFSDAIQVigsGALRGyK 385
|
410
....*....|....*.
gi 1938527557 394 DMRNSMFVATCCFFVI 409
Cdd:PRK01766 386 DTRVIFFITFIAYWVL 401
|
|
| PRK10189 |
PRK10189 |
EmmdR/YeeO family multidrug/toxin efflux MATE transporter; |
25-402 |
4.74e-08 |
|
EmmdR/YeeO family multidrug/toxin efflux MATE transporter;
Pssm-ID: 182293 [Multi-domain] Cd Length: 478 Bit Score: 55.13 E-value: 4.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 25 LAIPMVLSNITVPLLGLVDAAVIghlehSWY----LGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLVF 100
Cdd:PRK10189 34 LAVPIFIENLCVLLMGVLSTFLV-----SWLgkeaMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARAAA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 101 VQGVTMALGFAGVFLLLHSLVADLVFSL--SSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVII 178
Cdd:PRK10189 109 RQSLVIMTLFAVLLAVLIHFFGEQIIDLvaGDATPEVKALALTYLELTVWSYPAAAITLIGSGALRGAGNTKIPLLINGG 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 179 TNITNIVLDIVFVIGL-GWQ---VEGAAFASVMADYAG-------LTFGLICVYRIWAKkqlpspwdllkktshglSRFV 247
Cdd:PRK10189 189 MNILNIIISSILIYGLfSWQglgFVGAGLGLTISRYIGavaiiwvLMIGFNPALRISLK-----------------SYFK 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 248 KLNRDIFLR--SLCLQATFTFMTFQG---------ASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGakdK 316
Cdd:PRK10189 252 PLNFAIIWEvmGIGIPASIESVLFNGgklltqmfvAGMGTSVIAGNFIAFSIAALINLPGNALGSASTIITGTRLG---K 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 317 DELNQS--LIGTFFWSFNICLVLTIVFAIAGSSLI-NMITTIPDVKsQAEVYLPWLIA--MPLVSMWCFLLDGiFVGAtk 391
Cdd:PRK10189 329 GQIAQAerQLRHVFWLSTLGLTAIAWLSAPFAGLLaSFYTQDPDVK-HVVKILIWLNAlfMPIWAASWVLPAG-LKGA-- 404
|
410
....*....|.
gi 1938527557 392 gKDMRNSMFVA 402
Cdd:PRK10189 405 -RDARYAMWVS 414
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
14-340 |
1.03e-07 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 53.85 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 14 SNQAMHKKVLLLAIPMVLSNITVPLLGLVDAAVIGHlehswYLGGVALGGtmISVTFWLLGFLR-------MSTTGLAAQ 86
Cdd:PRK09575 6 MNQSIYRTFWRYTIPSIAAMLVNGLYQIVDGIFIGH-----YVGAEGLAG--INMAWPVIGIILgiglmvgMGTGSLLSI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 87 SYGANDGKQLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGT 166
Cdd:PRK09575 79 KRGEGDLEKAKRILTTGLLLLLLLGPIVSVILFLFADDFLRAQGAEGRTLELALQYIQVLIWGCLFTLGAIALPFLLRND 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 167 QNAKAPMWVVIITNITNIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFGLIcvYRIWAKKQLPSPWDLLKKTSHGLSRF 246
Cdd:PRK09575 159 ESPNLATGLMVIGALINIVLDYLFIGWLDWGLTGAAIATALAQLVVTVLGLG--YFFSSRANIRLTLKELRFNWSLAPKI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 247 VKLNRDiflrSLCLQATFTFM----TFQGASFGDDVVAANAVLMSFLMIISYGM-DGFAYAMEAMVGKAIGAKDKDELNQ 321
Cdd:PRK09575 237 VLLGSS----SFFMYLYGSFVvalhNRLFMEYGSALTVGAYAIVGYLMVLYYLVaEGIAEGMQPPVSYYFGARQYDNIKK 312
|
330
....*....|....*....
gi 1938527557 322 SLIGTFFWSFNICLVLTIV 340
Cdd:PRK09575 313 LLKLAMKVTVLAGIAWVLL 331
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
20-221 |
6.21e-07 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 51.56 E-value: 6.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 20 KKVLLLAIPMVLSNITVPLLGLVDAAVIGHLEHSWYLGGVALGGTMISVTFWLLGFLRMSTTGLAAQSYGANDGKQLGLV 99
Cdd:cd12082 219 RRLLRIGLPSAIQNSLLSLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRI 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 100 FVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIIT 179
Cdd:cd12082 299 TWVALLIGLLIGAVLGLLILLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLS 378
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1938527557 180 NITNIVLDIVFVIGLGWQVEGAAFASVMADYAGLTFGLICVY 221
Cdd:cd12082 379 YWVVRLPLAYVLAYLGLGLYGIWLALVISLILAALVLLLFFR 420
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
53-366 |
1.10e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 50.67 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 53 SWYLGGV---ALGGTMIS--VTFWLLGF---LRMSTTGLAAQSYGANDGKQLGLVFVQGVTMALGFAGVFLLLHSLVADL 124
Cdd:cd13145 33 TFFAGKIsteALAALSLSfpIFFIIIAIgvgIGTGTTALIGNALGAGDRRKARRYAAQGLSFGIILAILLTVIGLFAAPP 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 125 VFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFVILGWLLGTQNAKAPMWVVIITNITNIVLDIVFVIG----LGWQVEG 200
Cdd:cd13145 113 LFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYRNFLIIGFFLNIILDPLFIFGgggiPAMGVSG 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 201 AAFASVMADYAGLtfglicVYRIWAKKQLpspwdllkKTSHGLS-RFVKLNRDIF-----------LRSLCLQATFTFMT 268
Cdd:cd13145 193 IALATIISQFIGM------FYLLYKVRKS--------GIISGCRlRDFIPRLDVYkeilkqgfpasLNMMTIGLGIFVIT 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 269 FQGASFGDDVVAANAVLMSFLMIISYGMDGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVLTIVFAIAGSSL 348
Cdd:cd13145 259 YFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKYDRVRETYKKALKYGFVIMVVATVFLLFFAEPL 338
|
330
....*....|....*...
gi 1938527557 349 INMITTIPDVKSQAEVYL 366
Cdd:cd13145 339 MSLFTNDPAVIAIGAGYL 356
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
268-412 |
5.06e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 45.28 E-value: 5.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 268 TFQGASFGDDVVAANAV-LMSFLMIISYGMdGFAYAMEAMVGKAIGAKDKDELNQSLIGTFFWSFNICLVLTIVFAIAGS 346
Cdd:cd13145 33 TFFAGKISTEALAALSLsFPIFFIIIAIGV-GIGTGTTALIGNALGAGDRRKARRYAAQGLSFGIILAILLTVIGLFAAP 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1938527557 347 SLINMITTIPDVKSQAEVYLPWLIAMPLVSMWCFLLDGIFVGATKGKDMRNSMFVAtccFFVIFFL 412
Cdd:cd13145 112 PLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYRNFLIIG---FFLNIIL 174
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
79-194 |
5.80e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 38.84 E-value: 5.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1938527557 79 STTGLAAQSYGANDGKQLGLVFVQGVTMALGFAGVFLLLHSLVADLVFSLSSASDQVKHYGQQYFSIRAWSAPAALTNFV 158
Cdd:cd13141 294 AAPAIAGQNFGAGNYDRVRETFRITAILTTALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSWNFVAAGLVFT 373
|
90 100 110
....*....|....*....|....*....|....*.
gi 1938527557 159 ILGWLLGTQNAkapmWVVIITNITNIVLDIVFVIGL 194
Cdd:cd13141 374 CSGMFQALGNT----WPSLLSSASRLLTFALPVIWL 405
|
|
| |
