|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-908 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1446.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 1 MAKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 81 TSDDSGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDGRMSKEDLTNYVAS 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 161 HVLDPLSRVNGVGQTLLLGSQFSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGTPAKPGTVLQATITESTLL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 241 RTPEQFGNILLKVNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPHG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 321 LVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 401 AIGLLVDDAIVVVENVERVMAEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 481 SVLVALILTPALCATILKPVPQGHHEEKK-GFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLP 559
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKgGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 560 KSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLTSAEKDVVDSVFTVNGFSFAGRGQNAGLVFVKLKPYEQRQRS 639
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 640 DQKVQALIGRTFAHYSTYKDAMVIPFNPPSIPELGTAAGFDFELTDNAGLGHEALMAARGQLLGMAAKDPALALVRPNGL 719
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGL 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 720 NDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDtDGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGMVP 799
Cdd:TIGR00915 721 EDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFID-RGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 800 FSAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASKLPEGIGYSWTGLSFQEIQSGSQAPILYAIS 879
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900
....*....|....*....|....*....
gi 1956089783 880 ILVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGI 908
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-908 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 1343.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 1 MAKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 81 TSDDSGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDGRMSKEDLTNYVAS 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 161 HVLDPLSRVNGVGQTLLLGSQFSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGTPAKPGTVLQATITESTLL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 241 RTPEQFGNILLKVNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPHG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 321 LVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 401 AIGLLVDDAIVVVENVERVMAEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 481 SVLVALILTPALCATILKPVPQGHH-EEKKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLP 559
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHgEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 560 KSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLTSAEKDVVDSVFTVNGFSFAGRGQNAGLVFVKLKPYEQRQRS 639
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 640 DQKVQALIGRTFAHYSTYKDAMVIPFNPPSIPELGTAAGFDFELTDNAGLGHEALMAARGQLLGMAAKDP-ALALVRPNG 718
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPdMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 719 LNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDTdGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGMV 798
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDR-GRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMV 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 799 PFSAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASKLPEGIGYSWTGLSFQEIQSGSQAPILYAI 878
Cdd:PRK15127 800 PFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAI 879
|
890 900 910
....*....|....*....|....*....|
gi 1956089783 879 SILVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:PRK15127 880 SLIVVFLCLAALYESWSIPFSVMLVVPLGV 909
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-908 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1285.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 1 MAKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSS 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 81 TSDDSGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDGRMSKEDLTNYVAS 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 161 HVLDPLSRVNGVGQTLLLGSQFSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGTPAKPGTVLQATITESTLL 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 241 RTPEQFGNILLKVNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPHG 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 321 LVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 401 AIGLLVDDAIVVVENVERVMAEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVL 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 481 SVLVALILTPALCATILKPVPQGHHEEKKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLPK 560
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 561 SFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLTSAEKDVVDSVFTVNGFSFAGRGQNAGLVFVKLKPYEQRQRSD 640
Cdd:PRK10555 561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSKT 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 641 QKVQALIGRTFAHYSTYKDAMVIPFNPPSIPELGTAAGFDFELTDNAGLGHEALMAARGQLLGMAAKDPALALVRPNGLN 720
Cdd:PRK10555 641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTRVRHNGLD 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 721 DTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDTdGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGMVPF 800
Cdd:PRK10555 721 DSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDR-GRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPF 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 801 SAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASKLPEGIGYSWTGLSFQEIQSGSQAPILYAISI 880
Cdd:PRK10555 800 SAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISL 879
|
890 900
....*....|....*....|....*...
gi 1956089783 881 LVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:PRK10555 880 LVVFLCLAALYESWSVPFSVMLVVPLGV 907
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-908 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1103.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 1 MAKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 81 TSDDsGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDGRMSKEDLTNYVAS 160
Cdd:pfam00873 81 QSSY-GLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 161 HVLDPLSRVNGVGQ-TLLLGSQFSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIggtpakPGTVLQATITESTL 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDvQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 240 LRTPEQFGNILLKvNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPH 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 320 GLVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 400 LAIGLLVDDAIVVVENVERVMAEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMV 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 480 LSVLVALILTPALCATILKPVPQGHHeekKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLP 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH---GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIP 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 560 KSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLTsaEKDVVDSVFTVNGFSFAG--RGQNAGLVFVKLKPYEQRQ 637
Cdd:pfam00873 550 TEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILK--EKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERP 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 638 RSDQKVQALIGRTFAHYSTYKDAMVIPFNPPSIPELGTAAGFDFELTD-NAGLGHEALMAARGQLLGMAAKDPALALVRP 716
Cdd:pfam00873 628 GPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGLSDVRS 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 717 NGLNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDtDGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGG 796
Cdd:pfam00873 708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPE-GGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGK 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 797 MVPFSAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASK--LPEGIGYSWTGLSFQEIQSGSQAPI 874
Cdd:pfam00873 787 MIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPI 866
|
890 900 910
....*....|....*....|....*....|....
gi 1956089783 875 LYAISILVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:pfam00873 867 LIALALLVVFLVLAALYESWSDPLSIMLTVPLAL 900
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-908 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1033.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 1 MAKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 81 TSDDsGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDgrMSKEDLTNYVAS 160
Cdd:COG0841 83 TSSE-GSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 161 HVLDPLSRVNGVGQTLLLGS-QFSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGTpakpgtVLQATITESTL 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGG------DREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 240 LRTPEQFGNILLKVNqDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPH 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 320 GLVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 400 LAIGLLVDDAIVVVENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMV 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 480 LSVLVALILTPALCATILKPvpqGHHEEKKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLP 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKP---HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 560 KSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLtsAEKDVVDSVFTVNGFSFAGRGQNAGLVFVKLKPYEQRQRS 639
Cdd:COG0841 549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEIL--LEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRS 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 640 dqkVQALIGRTFAHYSTYKDAMVIPFNPPSiPELGTAAGFDFELTdnaGLGHEALMAARGQLLGMAAKDPALALVRPNGL 719
Cdd:COG0841 627 ---ADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSDLQ 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 720 NDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDtDGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGMVP 799
Cdd:COG0841 700 LGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNR-GGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVP 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 800 FSAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASK--LPEGIGYSWTGLSFQEIQSGSQAPILYA 877
Cdd:COG0841 779 LSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFL 858
|
890 900 910
....*....|....*....|....*....|.
gi 1956089783 878 ISILVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:COG0841 859 LALLLVYLVLAAQFESFIQPLIILLTVPLAL 889
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-908 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1015.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 1 MAKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSS 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 81 TSDdSGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDGRMSKEDLTNYVAS 160
Cdd:PRK09577 81 TSS-AGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 161 HVLDPLSRVNGVGQTLLLGSQFSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGTPAKPGTVLQATITESTLL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 241 RTPEQFGNILLKVNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPHG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 321 LVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 401 AIGLLVDDAIVVVENVERVMAEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVL 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 481 SVLVALILTPALCATILKPVPQGHHeEKKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLPK 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHH-EKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPT 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 561 SFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLtsAEKDVVDSVFTVNGFSFAGRGQNAGLVFVKLKPYEQRQRSD 640
Cdd:PRK09577 559 AFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYL--RRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAAR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 641 QKVQALIGRTFAHYSTYKDAMVIPFNPPSIPELGTAAGFDFELTDNAGLGHEALMAARGQLLGMAAKDPALALVRPNGLN 720
Cdd:PRK09577 637 DHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDLMFAGTQ 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 721 DTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDTDgRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGMVPF 800
Cdd:PRK09577 717 DAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGS-QVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 801 SAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASKLPEGIGYSWTGLSFQEIQSGSQAPILYAISI 880
Cdd:PRK09577 796 AAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALSV 875
|
890 900
....*....|....*....|....*...
gi 1956089783 881 LVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:PRK09577 876 LVVFLALAALYESWSIPFAVMLVVPLGV 903
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-908 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 587.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 5 FIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSSTSDd 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSS- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 85 SGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVV--QQLGMQVtKSSSNWLMWFAFNSEDgrMSKEDLTNYVASHV 162
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEApdPPVYRKA-NSADTPIMYIGLTSEE--MPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 163 LDPLSRVNGVGQTLLLGSQ-FSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGtpakPGTVLqaTITESTLLR 241
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQrPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRG----DSVVS--TVRANDQLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 242 TPEQFGNILLKVNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPHGL 321
Cdd:NF033617 234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 322 VVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLA 401
Cdd:NF033617 314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 402 IGLLVDDAIVVVENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVLS 481
Cdd:NF033617 394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 482 VLVALILTPALCATILKpvpqgHHEEKKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLPKS 561
Cdd:NF033617 473 GIVALTLTPMMCSRLLK-----ANEKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 562 FLPDEDQGYMFMIVQTPSGStqettgkTLDNINTYLTSAEKDVVD--SVFTVNGFSFAGR--GQNAGLVFVKLKPYEQRQ 637
Cdd:NF033617 548 LAPSEDRGVIFGMIQAPQSI-------SLDYMSAKMRDVEKILSSdpEVQSLTSFNGVGGnpGDNTGFGIINLKPWDERD 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 638 RSDQKVQALIGRTFAHYSTykdAMVIPFNPPSIPeLGTAAGFDFELTDNAGLGHEALMAARGQLLGMAAKDPALALVRPN 717
Cdd:NF033617 621 VSAQEIIDRLRPKLAKVPG---MDLFLFPLQDLP-GGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSD 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 718 GLNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFlDTDGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGM 797
Cdd:NF033617 697 LQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTI-YTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 798 VPFSAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAA-MEALASKLPEGIGYSWTGLSFQEIQSGSQAPILY 876
Cdd:NF033617 776 VPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEAlDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLF 855
|
890 900 910
....*....|....*....|....*....|..
gi 1956089783 877 AISILVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:NF033617 856 LLALAAIYLVLAIQYESFVDPLTILSTVPLAG 887
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-908 |
1.64e-142 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 449.28 E-value: 1.64e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 5 FIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSSTSDD 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 85 SGnATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQQLGMQVTKSSSNWLMWFAFNSEDgrMSKEDLTNYVaSHVLD 164
Cdd:PRK09579 87 NF-SIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSEE--MSNPQITDYL-SRVIQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 165 P-LSRVNGVGQTLLLGSQ-FSMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIggtpakPGTVLQATITESTLLRT 242
Cdd:PRK09579 163 PkLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEV------KGEYVVTSINASTELKS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 243 PEQFGNILLKVNQDgSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYFPHGLV 322
Cdd:PRK09579 237 AEAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 323 VHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAI 402
Cdd:PRK09579 316 VSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAI 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 403 GLLVDDAIVVVENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVLSV 482
Cdd:PRK09579 396 GLVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISG 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 483 LVALILTPALCATILKpvpqgHHEEKKGFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVGVMFTRLPKSF 562
Cdd:PRK09579 475 IVALTLSPMMCALLLR-----HEENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 563 LPDEDQGYMFMIVQTPSGStqettgkTLDNINTYLTSAEKDVVD-----SVFTVNGFSfagrGQNAGLVFVKLKPYEQRQ 637
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPA-------NLDYLNAYTDEFTPIFKSfpeyySSFQINGFN----GVQSGIGGFLLKPWNERE 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 638 RSDQKVQALIGRTFAHYSTYKdamVIPFNPPSIPelGTAAGFDFELTDNAGLGHEALMAARGQLLGMAAKDPALALVRPN 717
Cdd:PRK09579 619 RTQMELLPLVQAKLEEIPGLQ---IFGFNLPSLP--GTGEGLPFQFVINTANDYESLLQVAQRVKQRAQESGKFAFLDID 693
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 718 GLNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFlDTDGRIKKVYVQSDAPFRMTPEDMNIWYVRNSSGGM 797
Cdd:PRK09579 694 LAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRF-TIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQL 772
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 798 VPFSAFSSGHWIYGSPKLERYNGVSSIEIQG----QAAEGKSTGQAMAAMEAlasklPEGIGYSWTGLSFQEIQSGSQAP 873
Cdd:PRK09579 773 LPLSTLITLSDRARPRQLNQFQQLNSAIISGfpivSMGEAIETVQQIAREEA-----PEGFAFDYAGASRQYVQEGSALW 847
|
890 900 910
....*....|....*....|....*....|....*
gi 1956089783 874 ILYAISILVVFLCLAALYESWSIPFSVIMVVPLGV 908
Cdd:PRK09579 848 VTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSI 882
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-906 |
2.68e-96 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 325.44 E-value: 2.68e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 3 KFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSSTS 82
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 83 DdSGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQVVQ-QLGmQVTkSSSNWLMWFAFNSEDGRMSKEDLTNyVASH 161
Cdd:COG3696 87 R-FGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTpELG-PIS-TGLGEIYQYTLESDPGKYSLMELRT-LQDW 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 162 VLDP-LSRVNGVGQTLLLG---SQFsmRIWLDPTRLTNYGLTPIDVSTAItQQNVQIAGGQI---GGTpakpgtvlQATI 234
Cdd:COG3696 163 VIRPqLRSVPGVAEVNSFGgfvKQY--QVLVDPAKLRAYGLTLDDVIEAL-ERNNANVGGGYierGGQ--------EYLV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 235 TESTLLRTPEQFGNILLKvNQDGSQVRLKDVGRAALGSENYTFDTKYMGQ-PTAGLGIQLATGANALATATALRAKIDEL 313
Cdd:COG3696 232 RGIGLIRSLEDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEgEVVGGIVLMLKGENALEVIEAVKAKLAEL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 314 SKYFPHGLVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTL 393
Cdd:COG3696 311 KPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 394 SMFGLVLAIGLLVDDAIVVVENVERVMAE-----EGLSPKEATRKAMSQITGALV-GVALVLsAVFVPV-AFSGgsV-GA 465
Cdd:COG3696 391 SLGGLAIDFGIIVDGAVVMVENILRRLEEnraagTPRERLEVVLEAAREVRRPIFfATLIII-LVFLPIfTLEG--VeGK 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 466 IYRQFSLTIVSAMVLSVLVALILTPALCATILKpvpqGHHEEKKgffGWFNRTFDRsrdRYTGGVNHVIRRSGRWLVIYL 545
Cdd:COG3696 468 LFRPMALTVIFALLGALLLSLTLVPVLASLLLR----GKVPEKE---NPLVRWLKR---LYRPLLRWALRHPKLVLAVAL 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 546 AVFIAVGVMFTRLPKSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLtsaeKDV--VDSVftvngFSFAGR---- 619
Cdd:COG3696 538 VLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERIL----KSFpeVESV-----VSRTGRaeda 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 620 ----GQNAGLVFVKLKPYEQ--RQRSDQKVQALIGRTFAhystykdamVIP-----FNPP---SIPEL--GTAA------ 677
Cdd:COG3696 609 tdpmGVNMSETFVILKPRSEwrSGRTKEELIAEMREALE---------QIPgvnfnFSQPiqmRVDELlsGVRAdvavki 679
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 678 -GFDFELTDNAGLGHEALMAA-RGqllgmaAKDpaLALVRPNGLndtPQYKVDIDREKANALGVTAAAIDQTFSIAWASQ 755
Cdd:COG3696 680 fGDDLDVLRRLAEQIEAVLKTvPG------AAD--VQVERVTGL---PQLDIRIDRDAAARYGLNVADVQDVVETAIGGK 748
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 756 YVNNFLDTDGRIkKVYVQSDAPFRMTPEDM-NIwYVRNSSGGMVPFSAFSSGHWIYGSPKLERYNG---------VSSIE 825
Cdd:COG3696 749 AVGQVYEGERRF-DIVVRLPEELRDDPEAIrNL-PIPTPSGAQVPLSQVADIEVVEGPNQISRENGrrrivvqanVRGRD 826
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 826 IQGQAAEgkstgqamaAMEALAS--KLPEGIGYSWTGlSFQEIQSGSQ--ApILYAISILVVFLCLAALYESWSIPFSVI 901
Cdd:COG3696 827 LGSFVAE---------AQAKVAEqvKLPPGYYIEWGG-QFENLQRATArlA-IVVPLALLLIFLLLYLAFGSVRDALLIL 895
|
....*
gi 1956089783 902 MVVPL 906
Cdd:COG3696 896 LNVPF 900
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-905 |
7.04e-85 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 293.94 E-value: 7.04e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 5 FIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSSTSDd 84
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSS- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 85 SGNATITLTFSPGTNPDVAQVQVQNKLSLATPNLPQvvqqlGMQVTKS------SSNWLMWFAFNSEDgrMSKEDLTNYV 158
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPS-----GMPSRPTyrkanpSDAPIMILTLTSDT--YSQGQLYDFA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 159 ASHVLDPLSRVNGVGQTLLLGSQF-SMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIggtpakPGTVLQATITES 237
Cdd:PRK10614 159 STQLAQTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAV------EDGTHRWQIQTN 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 238 TLLRTPEQFGNILLKVNQdGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYF 317
Cdd:PRK10614 233 DELKTAAEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 318 PHGLVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFG 397
Cdd:PRK10614 312 PAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMA 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 398 LVLAIGLLVDDAIVVVENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSA 477
Cdd:PRK10614 392 LTIATGFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVA 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 478 MVLSVLVALILTPALCATILKPVPQGHHEEKKGffgwFNRTFDRSRDRYTGGVNHVIRRSgRWLVIYLAVFIAVGV-MFT 556
Cdd:PRK10614 471 IGISLLVSLTLTPMMCAWLLKSSKPREQKRLRG----FGRMLVALQQGYGRSLKWVLNHT-RWVGVVLLGTIALNVwLYI 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 557 RLPKSFLPDEDQGYMFMIVQT-PSGSTQETTGKTLDNINtyLTSAEKDvVDSvftVNGFSFAGRgQNAGLVFVKLKPYEQ 635
Cdd:PRK10614 546 SIPKTFFPEQDTGRLMGFIQAdQSISFQAMRGKLQDFMK--IIRDDPA-VDN---VTGFTGGSR-VNSGMMFITLKPLSE 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 636 RQRSDQKVqalIGRTFAHYSTYKDA--MVIPFNPPSIPELGTAAGFDFEL-TDNAGlgheALMAARGQLLGMAAKDPALA 712
Cdd:PRK10614 619 RSETAQQV---IDRLRVKLAKEPGAnlFLMAVQDIRVGGRQSNASYQYTLlSDDLA----ALREWEPKIRKALAALPELA 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 713 LVRPNGLNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDTDGRIkKVYVQSDAPFRMTPEDMNIWYVRN 792
Cdd:PRK10614 692 DVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQY-KVVMEVDPRYTQDISALEKMFVIN 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 793 SSGGMVPFSAFSsgHWiygspklERYNGVSSIEIQGQAA---------EGKSTGQAMAAMEALASKL--PEGI--GYSWT 859
Cdd:PRK10614 771 NEGKAIPLSYFA--KW-------QPANAPLSVNHQGLSAastisfnlpTGKSLSDASAAIERAMTQLgvPSTVrgSFAGT 841
|
890 900 910 920
....*....|....*....|....*....|....*....|....*.
gi 1956089783 860 GLSFQEIQSgSQApILYAISILVVFLCLAALYESWSIPFSVIMVVP 905
Cdd:PRK10614 842 AQVFQETMN-SQL-ILILAAIATVYIVLGILYESYVHPLTILSTLP 885
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
2-905 |
1.13e-80 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 282.39 E-value: 1.13e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 2 AKFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQ---MSGLDNflyM 78
Cdd:PRK10503 13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQfgqMSGLKQ---M 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 79 SSTSddSGNAT-ITLTFSPGTNPDVAQVQVQNKLSLATPNLPQvvqQLGMQVTKSSSNW----LMWFAFNSEDGRMSK-E 152
Cdd:PRK10503 90 SSQS--SGGASvITLQFQLTLPLDVAEQEVQAAINAATNLLPS---DLPNPPVYSKVNPadppIMTLAVTSTAMPMTQvE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 153 DLtnyVASHVLDPLSRVNGVGQTLLLGSQF-SMRIWLDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIGGtPAKpgtvlQ 231
Cdd:PRK10503 165 DM---VETRVAQKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG-PTR-----A 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 232 ATITESTLLRTPEQFGNILLKVnQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKID 311
Cdd:PRK10503 236 VTLSANDQMQSAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLP 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 312 ELSKYFPHGLVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSIN 391
Cdd:PRK10503 315 QLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSIN 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 392 TLSMFGLVLAIGLLVDDAIVVVENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFS 471
Cdd:PRK10503 395 NLTLMALTIATGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 472 LTIVSAMVLSVLVALILTPALCATILKPVPQGHHEEkkgFFGWFNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAV 551
Cdd:PRK10503 474 VTLAVAILISAVVSLTLTPMMCARMLSQESLRKQNR---FSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLT 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 552 GVMFTRLPKSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLTsaeKD-VVDSVFTVNGFSFAGRGQNAGLVFVKL 630
Cdd:PRK10503 551 VLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVIL---QDpAVQSLTSFVGVDGTNPSLNSARLQINL 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 631 KPYEQRqrsDQKVQALIGRTFAHYSTYKDAMVI--PFNPPSIPELGTAAGFDFELTDNAglgHEALMAARGQLLGMAAKD 708
Cdd:PRK10503 628 KPLDER---DDRVQKVIARLQTAVAKVPGVDLYlqPTQDLTIDTQVSRTQYQFTLQATS---LDALSTWVPKLMEKLQQL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 709 PALALVRPNGLNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLdTDGRIKKVYVQSDAPFRMTPEDMNIW 788
Cdd:PRK10503 702 PQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIY-TQANQYRVVLEHNTENTPGLAALDTI 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 789 YVRNSSGGMVPFSAFSSGHWIYGSPKLERYNGVSSIEIQGQAAEGKSTGQAMAAMEALASKL--PEGIGYSWTG--LSFQ 864
Cdd:PRK10503 781 RLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnlPADITTQFQGstLAFQ 860
|
890 900 910 920
....*....|....*....|....*....|....*....|.
gi 1956089783 865 EIQSGSQAPILYAisILVVFLCLAALYESWSIPFSVIMVVP 905
Cdd:PRK10503 861 SALGSTVWLIVAA--VVAMYIVLGVLYESFIHPITILSTLP 899
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
16-906 |
1.48e-51 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 196.52 E-value: 1.48e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 16 AIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYPGASAKTVEDTVTQVIEQQMSGLDNFLYMSSTSDdSGNATITLTFS 95
Cdd:TIGR00914 20 TLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSR-YGLSQVTVIFK 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 96 PGTNPDVAQVQVQNKLSLATPNLPQ-VVQQLGMQVTksSSNWLMWFAFNSEDGrMSKEDLTNY-------VASHVLDP-L 166
Cdd:TIGR00914 99 DGTDLYFARQLVNERLQQARDNLPEgVSPEMGPIST--GLGEIFLYTVEAEEG-ARKKDGGAYtltdlrtIQDWIIRPqL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 167 SRVNGVGQTLLLG---SQFSMRIwlDPTRLTNYGLTPIDVSTAITQQNVQIAGGQIggtpakpgtvlqATITESTLLRTP 243
Cdd:TIGR00914 176 RTVPGVAEVNSIGgyvKQFLVAP--DPEKLAAYGLSLADVVNALERNNQNVGAGYI------------ERRGEQYLVRAP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 244 EQ------FGNILLKvNQDGSQVRLKDVGRAALGSENYTFDTKYMGQPTAGLGIQLATGANALATATALRAKIDELSKYF 317
Cdd:TIGR00914 242 GQvqsmddIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 318 PHGLVVHYPYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFG 397
Cdd:TIGR00914 321 PEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 398 lvLAIGLLVDDAIVVVENVERVMAE----EGLSPKEATR-----KAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYR 468
Cdd:TIGR00914 401 --LDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFH 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 469 QFSLTIVSAMVLSVLVALILTPALCATILKpvpqGHHEEKKgffgwfNRTFDRSRDRYTGGVNHVIRRSGRWLVIYLAVF 548
Cdd:TIGR00914 479 PMAFTVVLALAGAMILSLTFVPAAVALFIR----GKVAEKE------NRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 549 IAVGVMFTRLPKSFLPDEDQGYMFMIVQTPSGSTQETTGKTLDNINTYLTSAEKdvVDSVFTVNGFSFAGRGQ---NAGL 625
Cdd:TIGR00914 549 VLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPE--VARVFAKTGTAEIATDPmppNASD 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 626 VFVKLKPYEQ----RQRSDQKVQALIGRTFAHYSTYKDamvipFNPP---SIPELGTAAGFDFEL----TDNAGLGHEAl 694
Cdd:TIGR00914 627 TYIILKPESQwpegKKTKEDLIEEIQEATVRIPGNNYE-----FTQPiqmRFNELISGVRSDVAVkvfgDDLDDLDATA- 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 695 maarGQLLGMAAKDPALALVRPNGLNDTPQYKVDIDREKANALGVTAAAIDQTFSIAWASQYVNNFLDTDGRIKKVyVQS 774
Cdd:TIGR00914 701 ----EKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIV-IRL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 775 DAPFRMTPEDMNIWYVR--NSSGGM---VPFSAFSSGHWIYGSPKLERYNGVSSIEIQGQaAEGKSTGQAMA-AMEALAS 848
Cdd:TIGR00914 776 PESLRESPQALRQLPIPlpLSEDARkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSAN-VRGRDLGSFVDdAKKAIAE 854
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1956089783 849 --KLPEGIGYSWTGlSFQEIQSGSQA-PILYAISILVVFLCLAALYESWSIPFSVIMVVPL 906
Cdd:TIGR00914 855 qvKLPPGYWITWGG-QFEQLQSATKRlQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPF 914
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
311-568 |
5.46e-19 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 92.23 E-value: 5.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 311 DELSKYFPHGLVVHY---PYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAG 387
Cdd:COG1033 188 AIIAKYEDPGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLG 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 388 FSINTLSM--FGLVLAIGllVDDAIVVVENVERVMAeEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSggSVGA 465
Cdd:COG1033 268 IPLSPLTIlvPPLLLAIG--IDYGIHLLNRYREERR-KGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFS--DIPP 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 466 IyRQFSLTIVSAMVLSVLVALILTPALCATILKPVPQGHHEEKKGFFGWFNRTFDRsrdrytggvnHVIRRSGRWLVIYL 545
Cdd:COG1033 343 I-RDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLAR----------FVLRRPKVILVVAL 411
|
250 260
....*....|....*....|....*...
gi 1956089783 546 AVFIAVGVMFTRL-----PKSFLPDEDQ 568
Cdd:COG1033 412 VLAVVSLYGISRLkveydFEDYLPEDSP 439
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
337-496 |
1.76e-18 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 90.69 E-value: 1.76e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 337 IEEVVKTLIEG----IVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVV 412
Cdd:COG1033 600 NESVIESQIRSlllaLLLIFLLLLLAFRSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHF 679
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 413 VENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGgsvGAIYRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:COG1033 680 LSRYREER-RKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSS---FPPLADFGLLLALGLLVALLAALLLLPAL 755
|
....
gi 1956089783 493 CATI 496
Cdd:COG1033 756 LLLL 759
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-492 |
2.87e-16 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 84.00 E-value: 2.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 3 KFFIDRPIFAWVIAIVLMLAGVASIFKMPIAQYPTIAPPTIQIQANYP-GASAKTVEDTVTQVIE--QQMSGLDNFLYMS 79
Cdd:COG0841 520 RWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQIIVSVQLPpGTSLERTEAVVRQVEEilLEVPEVESVFSVV 599
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 80 STSDDSG---NATITLTFSPGTNPDVAQVQVQNKLSLATPNLPqvvqqlGMQVtksssnwlmwFAFNSEDGRMSK----- 151
Cdd:COG0841 600 GFSGGGSgsnSGTIFVTLKPWDERDRSADEIIARLREKLAKIP------GARV----------FVFQPPAGGLGSgapie 663
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 152 --------EDLTNyVASHVLDPLSRVNGVGQ---TLLLGSQfSMRIWLDPTRLTNYGLTPIDVSTAitqqnVQIA-GGQI 219
Cdd:COG0841 664 vqlqgddlEELAA-AAEKLLAALRQIPGLVDvrsDLQLGKP-ELQLDIDREKAAALGVTVADVAST-----LRAAlGGRY 736
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 220 GGTPAKPGT----VLQAtitESTLLRTPEQFGNILLKvNQDGSQVRLKDVGRAalgSENYTFD--TKYMGQPTAGLGIQL 293
Cdd:COG0841 737 VNDFNRGGReydvRVQA---PEEDRNSPEDLENLYVR-TPDGEMVPLSSVATI---EEGTGPSsiNRYNGQRSVTVSANL 809
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 294 ATGANALATATALRAKIDELSkyFPHGLVVHYPYDTtpfvrLSIEEVVKTLIEGIVLVFLVMYLFL----QNLRATIIPT 369
Cdd:COG0841 810 APGVSLGEALAAIEELAAELK--LPPGVSIEFTGQA-----EEEQESFSSLGLAFLLALLLVYLVLaaqfESFIQPLIIL 882
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 370 IAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMaEEGLSPKEATRKA---------MSQITg 440
Cdd:COG0841 883 LTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLR-EEGMSLREAILEAarlrlrpilMTSLA- 960
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|..
gi 1956089783 441 ALVGValvlsavfVPVAFSGGSVGAIYRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:COG0841 961 TILGL--------LPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVL 1004
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
347-492 |
4.17e-14 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 76.95 E-value: 4.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 347 GIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMAEEGLS 426
Cdd:pfam00873 871 ALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKS 950
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1956089783 427 PKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:pfam00873 951 LEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVF 1016
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
311-568 |
8.81e-11 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 65.56 E-value: 8.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 311 DELSKYFPHGLVVHY---PYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAI----- 382
Cdd:COG2409 139 DAVAAAPAPGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLlalla 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 383 --MGVAGFSINTLSMfgLVLAIGllVDDAIVVV----ENVERvmaeeGLSPKEATRKAMSQitgalVGVALVLSAVFVPV 456
Cdd:COG2409 219 afTDVSSFAPNLLTM--LGLGVG--IDYALFLVsryrEELRA-----GEDREEAVARAVAT-----AGRAVLFSGLTVAI 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 457 AFSGGSVG--AIYRQFSLTIVSAMVLSVLVALILTPALCATIlkpvpqGHHeekkgFFGWFNRTFDRSRDRYTGG----V 530
Cdd:COG2409 285 ALLGLLLAglPFLRSMGPAAAIGVAVAVLAALTLLPALLALL------GRR-----VFWPRRPRRRRAAAPESGFwrrlA 353
|
250 260 270
....*....|....*....|....*....|....*...
gi 1956089783 531 NHVIRRSGRWLVIYLAVFIAVGVMFTRLPKSFlPDEDQ 568
Cdd:COG2409 354 RAVVRRPVPVLVAAVAVLLALALPALGLRLGL-PDADS 390
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
317-496 |
8.59e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 59.47 E-value: 8.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 317 FPHGLVVHYPYDttPFVRLSIEE------VVKTLIEGIVLVfLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSI 390
Cdd:TIGR00921 169 PPSGKFLDVTGS--PAINYDIERefgkdmGTTMAISGILVV-LVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 391 NTLSMFGLVLAIGLLVDDAIVVVENVERVMaEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGgsVGAIyRQF 470
Cdd:TIGR00921 246 YATTLLAVPMLIGVGIDYGIQTLNRYEEER-DIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSE--FPMV-SEF 321
|
170 180
....*....|....*....|....*.
gi 1956089783 471 SLTIVSAMVLSVLVALILTPALCATI 496
Cdd:TIGR00921 322 GLGLVAGLITAYLLTLLVLPALLQSI 347
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
336-492 |
7.03e-08 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 55.76 E-value: 7.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 336 SIEEVVKTLIEGIVLVFLVMYLFLQnlRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVEN 415
Cdd:TIGR01129 246 SIEAGIKAGLIGLVLVLVFMILYYR--LFGLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYER 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 416 VERVMAeEGLSPKEAT----RKAMSQITGAlvGVALVLSAVFVpVAFSGGSVgaiyRQFSLTIVSAMVLSVLVALILTPA 491
Cdd:TIGR01129 324 IKEELR-LGKSVRQAIeagfERAFSTIFDA--NITTLIAALIL-YVFGTGPV----KGFAVTLAIGIIASLFTALVFTRL 395
|
.
gi 1956089783 492 L 492
Cdd:TIGR01129 396 L 396
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
342-538 |
1.38e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 54.61 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 342 KTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAI---------MGVAGFSINTLSMfgLVLAIGllVDDAIVV 412
Cdd:pfam03176 146 LIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLvailahilgIGLSTFALNLLVV--LLIAVG--TDYALFL 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 413 VEnveRVMAE--EGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVgaiYRQFSLTIVSAMVLSVLVALILTP 490
Cdd:pfam03176 222 VS---RYREElrAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPV---FAQVGPTIAIGVLVDVLAALTLLP 295
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1956089783 491 ALCATIlkpvpqghheekkGFFGWFNRTFDRSRDRYTGGVNHVIRRSG 538
Cdd:pfam03176 296 ALLALL-------------GRWGLWPPKRDRTARWWRRIGRLVVRRPA 330
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
348-491 |
1.55e-07 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 55.41 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 348 IVLVFLVMYLFL----QNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMAEE 423
Cdd:NF033617 855 FLLALAAIYLVLaiqyESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQ 934
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1956089783 424 GLSPKEATRKA---------MSqiTGALVGVALvlsavfvPVAFSGGsVGAIYRQ-FSLTIVSAMVLSVLVALILTPA 491
Cdd:NF033617 935 GLSRREAIYQAaalrlrpilMT--TLAMLLGAI-------PLMLSTG-AGAESRFpLGIVIVGGLGVGTLFTLFVLPV 1002
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
347-491 |
1.79e-07 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 55.24 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 347 GIVLVFLVMYLFLQNLRATIIpTIAVPVV-LLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIvvvenverVMAEEGL 425
Cdd:COG4258 648 ALLLILLLLLLRLRSLRRALR-VLLPPLLaVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL--------FFTEGLL 718
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1956089783 426 SPKEATRkamsqitgALVGVAL-VLSAV--FVPVAFSggSVGAIyRQFSLTIVSAMVLSVLVALILTPA 491
Cdd:COG4258 719 DKGELAR--------TLLSILLaALTTLlgFGLLAFS--STPAL-RSFGLTVLLGILLALLLAPLLAPR 776
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
333-614 |
2.94e-07 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 54.62 E-value: 2.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 333 VRLSIEEVvKTLIEGI--------VLVFLVMYLFLQNLR--ATIIPTIAVPVVLLGTFAIMGVAgfSINTLSMFGLVLAI 402
Cdd:TIGR03480 257 VALSDEEL-ATVSEGAtvagllsfVLVLVLLWLALRSPRlvFAVLVTLIVGLILTAAFATLAVG--HLNLISVAFAVLFI 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 403 GLLVDDAIVVVenverVMAEEGLSPKEATRKAMSqITGALVGVALVLSAV--------FVPVAFSGGSvgaiyrqfSLTI 474
Cdd:TIGR03480 334 GLGVDFAIQFS-----LRYREERFRGGNHREALS-VAARRMGAALLLAALataagffaFLPTDYKGVS--------ELGI 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 475 VSA--MVLSVLVALILTPALCaTILKPVPQGHHEekkgffgwfnrtfdrsRDRYTGGVNHVIRRSGRWLVIylaVFIAVG 552
Cdd:TIGR03480 400 IAGtgMFIALFVTLTVLPALL-RLLRPPRRRKPP----------------GYATLAPLDAFLRRHRRPVLG---VTLILG 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 553 V---------------MFTRLPKS--------FLPDEDQGYMFMIVQTPSGSTQETTGKTLdnintyltsAEKDVVDSVF 609
Cdd:TIGR03480 460 IaalallpqlrfdfnpLNLQDPKTesvrtfleLLADPDTSPYSAEVLAPSAPEARALTERL---------EALPEVDQVV 530
|
....*
gi 1956089783 610 TVNGF 614
Cdd:TIGR03480 531 TLPDF 535
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
317-492 |
3.11e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.46 E-value: 3.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 317 FPHGLVVHY---PYDTTPFVRLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAG--FSIN 391
Cdd:TIGR00921 543 PPPGVKVGVtglPVAFAEMHELVNEGMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIGSGILWAIGLMGLRGipSFLA 622
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 392 TLSMFGLVLAIGllVDDAIVVVENVERVMAEegLSPKEATRKAMSQitgalVGVALVLSAVFVPVAFSG--GSVGAIYRQ 469
Cdd:TIGR00921 623 MATTISIILGLG--MDYSIHLAERYFEERKE--HGPKEAITHTMER-----TGPGILFSGLTTAGGFLSllLSHFPIMRN 693
|
170 180
....*....|....*....|...
gi 1956089783 470 FSLTIVSAMVLSVLVALILTPAL 492
Cdd:TIGR00921 694 FGLVQGIGVLSSLTAALVVFPAL 716
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
348-501 |
5.99e-07 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 53.68 E-value: 5.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 348 IVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMAEEGLSP 427
Cdd:PRK09579 854 LAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSR 933
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1956089783 428 KEATRKAMS-QITGALVGVALVLSAVfVPVAFSGGSvGAIYR-QFSLTIVSAMVLSVLVALILTPALCATILKPVP 501
Cdd:PRK09579 934 REAIEEAAAiRLRPVLMTTAAMVFGM-VPLILATGA-GAVSRfDIGLVIATGMSIGTLFTLFVLPCIYTLLAKPDA 1007
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
348-498 |
2.63e-06 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 51.30 E-value: 2.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 348 IVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVeRVMAEEGLSP 427
Cdd:TIGR00914 888 LLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFI-RKLLEEGPSL 966
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1956089783 428 KEATRK-AMSQITGALVgVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVLSVLVALILTPALCATILK 498
Cdd:TIGR00914 967 DEAVYEgALTRVRPVLM-TALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHR 1037
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
348-492 |
3.58e-06 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 50.80 E-value: 3.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 348 IVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMaEEGLSP 427
Cdd:COG3696 874 LLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLR-AEGLDL 952
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1956089783 428 KEATRKamsqitGALVGV------ALVLSAVFVPVAFSGGsVGA-IYRQFSLTIVSAMVLSVLVALILTPAL 492
Cdd:COG3696 953 REAIIE------GALERLrpvlmtALVAALGLLPMALSTG-PGSeVQRPLATVVIGGLITSTLLTLLVLPAL 1017
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
336-486 |
5.79e-06 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 48.02 E-value: 5.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 336 SIEEVVKTLIEGIVLVFLVMYLFLQnLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVEN 415
Cdd:TIGR00916 45 LIKAGIIALLIGLVLVLLYMLLRYE-WRGAIAAIAALVHDVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDR 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1956089783 416 V-ERVMAEEGLSPKEATRKAMSQ-ITGALVGVALVLSAVFVPVAFSGGSVgaiyRQFSLTIVSAMVLSVLVAL 486
Cdd:TIGR00916 124 IrEELRKYKGRTFREAINLGINQtLSRIIDTNVTTLLAVLALYVFGGGAI----KGFALTLGIGVIAGTYSSI 192
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-492 |
6.58e-06 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 49.73 E-value: 6.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 336 SIEEVVKTLIEGIVLVFLVMYLFLQNLR-ATIIPTIAVPVVLLGTFAIMGVagfsinTLSM---FGLVLAIGLLVDDaiv 411
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFMLLYYRLPGlVANIALALNVVLLLGVLSLLGA------TLTLpgiAGIILTIGMAVDA--- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 412 vveNV---ERVMAE--EGLSPKEAT----RKAM-----SQITGALVGVALvlsavFVpvaFSGGSVgaiyRQFSLTIVSA 477
Cdd:COG0342 340 ---NVlifERIREElrAGRSLRAAIeagfKRAFstildANVTTLIAAVVL-----FV---LGTGPV----KGFAVTLILG 404
|
170
....*....|....*
gi 1956089783 478 MVLSVLVALILTPAL 492
Cdd:COG0342 405 ILISMFTAVPVTRPL 419
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
336-557 |
3.45e-05 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 47.53 E-value: 3.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 336 SIEEVVKTLIEGIVLVFLVMyLFLQNLrATIIPTIAVPVVLLGTFAIMGVAGFsinTLSM---FGLVLAIGLLVDDAIVV 412
Cdd:PRK13024 264 AIDAGIIAGIIGFALIFLFM-LVYYGL-PGLIANIALLLYIFLTLGALSSLGA---VLTLpgiAGLVLGIGMAVDANVLI 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 413 VENVErvmaEE---GLSPKEATRKAM---------SQITGALVGVALvlsavFVpvaFSGGSVgaiyRQFSLTIVSAMVL 480
Cdd:PRK13024 339 FERIK----EElrkGKSLKKAFKKGFknafstildSNITTLIAAAIL-----FF---FGTGPV----KGFATTLIIGILA 402
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1956089783 481 SVLVALILTPALCATILKpvpqgHHEEKKGFFGWFNRTFDRSRDRYTGGVN-HVIRRSGRWLVIYLAVFIA-VGVMFTR 557
Cdd:PRK13024 403 SLFTAVFLTRLLLELLVK-----RGDKKPFLFGVKKKKIHNINEGVTIFDRiDFVKKRKWFLIFSIVLVIAgIIIFFIF 476
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
337-492 |
1.67e-04 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 45.42 E-value: 1.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 337 IEEVVKTLIEGIVLVFLVM----YLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVV 412
Cdd:pfam02460 634 YLTILPSTIQNIVITLICMfivcFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHI 713
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 413 VENVERvmaEEGLSPKEATRKAMSQI-----TGALVGVALVLSAVFVPVafsggsvgAIYRQFSLTIVSAMVLSVLVALI 487
Cdd:pfam02460 714 AYHFVR---SRGDTPAERVVDALEALgwpvfQGGLSTILGVLVLLFVPS--------YMVVVFFKTVFLVVAIGLLHGLF 782
|
....*
gi 1956089783 488 LTPAL 492
Cdd:pfam02460 783 ILPII 787
|
|
| Stt3 |
COG1287 |
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, ... |
343-459 |
7.21e-04 |
|
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440898 [Multi-domain] Cd Length: 774 Bit Score: 43.24 E-value: 7.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 343 TLIEGIVLVFLVMYLFLQNLRATIIPTIAVP-VVLLGTFAIMGVA-----GFSINTLSMFGLVLAIGLLVddAIVVVENV 416
Cdd:COG1287 224 VLFVGILALFALLQLLLDLLRGRSPEYLAIVgAVSFAVAALLVLPfiprlGFSGTGLSLLQPLLALALAA--GTVFLAWL 301
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1956089783 417 ERVmaeegLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFS 459
Cdd:COG1287 302 ARE-----LERRDLPRLYYPAALVGLVAAGLALLAVLLPRVLA 339
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
348-492 |
1.11e-03 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 42.83 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 348 IVLVFLVMYLFLqnlRATIIPTIAVPVVLLGTFAIMGVA-----------GFSINTLSMFGLVLAIGLLV----DDAIVV 412
Cdd:COG2409 527 LGLIFLLLLLLF---RSVVAPLKAVLTNLLSLGAALGVLvlvfqhgwlllGFTPGPLDSFVPLLLFVILFglgmDYEVFL 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 413 VENVeRVMAEEGLSPKEATRKAMSQ----ITGAlvgvALVLSAVFvpVAFSGGSVGAIyRQFSLTIVSAMVL-SVLVALI 487
Cdd:COG2409 604 VSRI-REEYDRGGGTREAVIRGLARtgrvITSA----ALIMAAVF--AAFATSPLVFL-KQIGFGLAVGVLLdAFVVRML 675
|
....*
gi 1956089783 488 LTPAL 492
Cdd:COG2409 676 LVPAL 680
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
347-490 |
1.13e-03 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 42.79 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 347 GIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMaEEGLS 426
Cdd:TIGR00915 879 SLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELM-AQGKS 957
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1956089783 427 PKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVLSVLVALILTP 490
Cdd:TIGR00915 958 IVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVP 1021
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
350-496 |
1.20e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 42.92 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 350 LVFLVMYLFLQNLRAT-IIPTIAVPVVLLGTF-AIMGVA--GFSINTLSMFGLVLAIGLLVDDAIVVVEnVERVMAEEGL 425
Cdd:PRK09577 873 LSVLVVFLALAALYESwSIPFAVMLVVPLGVIgAVLGVTlrGMPNDIYFKVGLIATIGLSAKNAILIVE-VAKDLVAQRM 951
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1956089783 426 SPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAIYRQFSLTIVSAMVLSVLVALILTPALCATI 496
Cdd:PRK09577 952 SLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
310-490 |
1.73e-03 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 42.20 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 310 IDELSKYFPHGLvvhyPYDTTPFV---RLSIEEVVKTLIEGIVLVFLVMYLFLQNLRATIIPTIAVPVVLLGTFAIMGVA 386
Cdd:PRK15127 844 MEELASKLPTGV----GYDWTGMSyqeRLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFR 919
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 387 GFSINTLSMFGLVLAIGLLVDDAIVVVENVERVMAEEGLSPKEATRKAMSQITGALVGVALVLSAVFVPVAFSGGSVGAI 466
Cdd:PRK15127 920 GLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGA 999
|
170 180
....*....|....*....|....
gi 1956089783 467 YRQFSLTIVSAMVLSVLVALILTP 490
Cdd:PRK15127 1000 QNAVGTGVMGGMVTATVLAIFFVP 1023
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
347-552 |
5.28e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 40.47 E-value: 5.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 347 GIVLVFLVMYLFLQNLraTIIPTIAVPVVLLGTFAIMGVAGFSINTLSMFGLVLAIGLLVDDAIVVVENVeRVMAEEGLS 426
Cdd:PRK14726 381 AAILVAALMIGFYGFL--GVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERI-REEEKTGHS 457
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 427 PKEATRKAMSQITGALV--GVALVLSAVfvpVAFSGGSvGAIyRQFSLTIVSAMVLSVLVALILTPALCATIL---KPvp 501
Cdd:PRK14726 458 LIQALDRGFSRALATIVdaNVTILIAAV---ILFFLGS-GAV-RGFAVTLAVGILTTVFTAFTLTRSLVAVWLrrrRP-- 530
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1956089783 502 qghHEEKKGFFGWFnrtFDRSRDRYTGGVNHVIRRSGRWLVIYLAVFIAVG 552
Cdd:PRK14726 531 ---KHLPKGVRTGL---FEGANIRFMGIRRYVFTLSAALSLASLVLFATVG 575
|
|
| NhaP |
COG0025 |
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism]; |
345-488 |
7.05e-03 |
|
NhaP-type Na+/H+ or K+/H+ antiporter [Inorganic ion transport and metabolism];
Pssm-ID: 439796 [Multi-domain] Cd Length: 506 Bit Score: 39.95 E-value: 7.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 345 IEGIVLVFLVMYLF-------LQNLRATIIP-----TIAVPV-VLLGTFAIMGVAGFSINTLSMFGLVLAigllVDDAIV 411
Cdd:COG0025 54 LEPLLELFLPPLLFeaalnldLRELRRNGRPilrlaVVGVLLtTLAVALAAHWLLGLPLAAALLLGAILA----PTDPVA 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 412 VVENVERVMAEEGLspkeatrkaMSQITG-ALV--GVALVLSAVFVPVAFSGG-SVGAIYRQFSLTIVSAMVLSVLVALI 487
Cdd:COG0025 130 VSPILRRLGVPKRL---------RTILEGeSLLndATALVLFVLALAAALGGGfSLGEALLDFLLAILGGILVGLLLGWL 200
|
.
gi 1956089783 488 L 488
Cdd:COG0025 201 L 201
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
336-492 |
7.99e-03 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 39.82 E-value: 7.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 336 SIEEVVKTLIEGIVLVFLVMYLFLQnlRATIIPTIAVPVVLLGTFAIMGVAGFSInTL-SMFGLVLAIGLLVdDAIVVVe 414
Cdd:PRK05812 295 SIRAGLIAGLIGLALVLLFMILYYR--LFGLIANIALVANLVLILAVLSLLGATL-TLpGIAGIVLTIGMAV-DANVLI- 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 415 nVERVMAE--EGLSPKEAT----RKAM-----SQITGALVGVALvlsavFvpvAFSGGSVgaiyRQFSLTIVSAMVLSVL 483
Cdd:PRK05812 370 -FERIREElrEGRSLRSAIeagfKRAFstildSNITTLIAAIIL-----Y---ALGTGPV----KGFAVTLGIGILTSMF 436
|
....*....
gi 1956089783 484 VALILTPAL 492
Cdd:PRK05812 437 TAITVTRAL 445
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
373-490 |
8.31e-03 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 40.10 E-value: 8.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1956089783 373 PVVLLGTFAIMGV----------AGFSIntLSMFGLVLAIGLLVDDAIVVVENVERVMAEEGLSPKEAT--------RKA 434
Cdd:PRK10614 877 PLTILSTLPSAGVgallalelfnAPFSL--IALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIfqacllrfRPI 954
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1956089783 435 MSQITGALVGvALvlsavfvPVAFSGGSvGAIYRQ-FSLTIVSAMVLSVLVALILTP 490
Cdd:PRK10614 955 MMTTLAALFG-AL-------PLVLSGGD-GAELRQpLGITIVGGLVMSQLLTLYTTP 1002
|
|
| |
