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Conserved domains on  [gi|1970150486|ref|WP_202861940|]
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type VI secretion system lipoprotein TssJ [Klebsiella oxytoca]

Protein Classification

type VI secretion lipoprotein TssJ( domain architecture ID 10007514)

type VI secretion lipoprotein TssJ is an outer membrane-associated component that forms the core complex with TssL and TssM inner-membrane proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3521 COG3521
Predicted component of the type VI protein secretion system [Intracellular trafficking, ...
 1-179 4.28e-49

Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442743  Cd Length: 168  Bit Score: 156.28  E-value: 4.28e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486   1 MLRITSIKRSTLLLIPLM--LTGCGLTQKisdgtssvVKSVFYKPVKTLHLDVTGRAELNTDERENASfsqPVMVWVYQL 78
Cdd:COG3521     1 MKKRLKRLARLLLLLLLLllLAGCGSTQK--------VTVIFYKQPTTLHLTLTAAPDLNPDANGRPS---PVVVRVYQL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  79 RDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASLDMPMDERTQFIAVVGLFRAPDmvRNDWKLVLRRDDLEP 158
Cdd:COG3521    70 KDDSAFESADFFALLDDDEEALGADLLSVKELTLLPGESKTLDLPLDPEARYIGVVALFRDPD--GARWRLVIPVPELDS 147

                         170       180
                  ....*....|....*....|.
gi 1970150486 159 DKPRVIEASQHRLTLQPKKDD 179
Cdd:COG3521   148 DGKLTIELGGNAITLVPEKEV 168
 
Name Accession Description Interval E-value
COG3521 COG3521
Predicted component of the type VI protein secretion system [Intracellular trafficking, ...
 1-179 4.28e-49

Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442743  Cd Length: 168  Bit Score: 156.28  E-value: 4.28e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486   1 MLRITSIKRSTLLLIPLM--LTGCGLTQKisdgtssvVKSVFYKPVKTLHLDVTGRAELNTDERENASfsqPVMVWVYQL 78
Cdd:COG3521     1 MKKRLKRLARLLLLLLLLllLAGCGSTQK--------VTVIFYKQPTTLHLTLTAAPDLNPDANGRPS---PVVVRVYQL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  79 RDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASLDMPMDERTQFIAVVGLFRAPDmvRNDWKLVLRRDDLEP 158
Cdd:COG3521    70 KDDSAFESADFFALLDDDEEALGADLLSVKELTLLPGESKTLDLPLDPEARYIGVVALFRDPD--GARWRLVIPVPELDS 147

                         170       180
                  ....*....|....*....|.
gi 1970150486 159 DKPRVIEASQHRLTLQPKKDD 179
Cdd:COG3521   148 DGKLTIELGGNAITLVPEKEV 168
T6SS-SciN pfam12790
Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of ...
 45-169 1.67e-30

Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of E coli is the production of toxins which it produces from dedicated machineries called secretion systems. Seven secretion systems have been described, which assemble from 3 to up to more than 20 subunits. These secretion systems derive from or have co-evolved with bacterial organelles such as ABC transporters (type I), type IV pili (type 2), flagella (type 3), or conjugative machines (type IV). The type VI secretion system (T6SS) is present in most pathogens that have contact with animals, plants, or humans. SciN is a lipoprotein tethered to the outer membrane and expressed in the periplasm of E coli and is essential for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation.


Pssm-ID: 432786  Cd Length: 120  Bit Score: 107.29  E-value: 1.67e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  45 KTLHLDVTGRAELNTDERENASfsqPVMVWVYQLRDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASLDMPM 124
Cdd:pfam12790   1 TTLDLTLVAAADLNPDENGRPS---PVVVRVYQLKDDSAFNAADFFSLYDDDKAALGADLVAVDEFILRPGETRTLSLPL 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1970150486 125 DERTQFIAVVGLFRAPDmvRNDWKLVLRRDDLEPDKPRVIEASQH 169
Cdd:pfam12790  78 DPGARYVGVVAAYRDLD--NARWRLVIPIPEAGEKNPLTVELDAN 120
VI_chp_3 TIGR03352
type VI secretion lipoprotein, VC_A0113 family; Work by Mougous, et al. (2006), describes ...
 41-164 3.80e-15

type VI secretion lipoprotein, VC_A0113 family; Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274535  Cd Length: 130  Bit Score: 68.05  E-value: 3.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  41 YKPVKTLHLDVTGRAELNTDERENASfsqPVMVWVYQLRDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASL 120
Cdd:TIGR03352   6 PKEPTYVTLTLTAAPDVNPDADGRAS---PVVVRVYELKSDTKFEAADFFALTEDAKKALGDDLIETDEIILLPGEKRKI 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1970150486 121 DMPMDERTQFIAVVGLFRAPDMVRndWKLVLRRDDLEPDKPRVI 164
Cdd:TIGR03352  83 TITLDEGTRYIGVVAAYRDIDNAE--WRVVYKVPPKGKYTIDVM 124
 
Name Accession Description Interval E-value
COG3521 COG3521
Predicted component of the type VI protein secretion system [Intracellular trafficking, ...
 1-179 4.28e-49

Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442743  Cd Length: 168  Bit Score: 156.28  E-value: 4.28e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486   1 MLRITSIKRSTLLLIPLM--LTGCGLTQKisdgtssvVKSVFYKPVKTLHLDVTGRAELNTDERENASfsqPVMVWVYQL 78
Cdd:COG3521     1 MKKRLKRLARLLLLLLLLllLAGCGSTQK--------VTVIFYKQPTTLHLTLTAAPDLNPDANGRPS---PVVVRVYQL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  79 RDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASLDMPMDERTQFIAVVGLFRAPDmvRNDWKLVLRRDDLEP 158
Cdd:COG3521    70 KDDSAFESADFFALLDDDEEALGADLLSVKELTLLPGESKTLDLPLDPEARYIGVVALFRDPD--GARWRLVIPVPELDS 147

                         170       180
                  ....*....|....*....|.
gi 1970150486 159 DKPRVIEASQHRLTLQPKKDD 179
Cdd:COG3521   148 DGKLTIELGGNAITLVPEKEV 168
T6SS-SciN pfam12790
Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of ...
 45-169 1.67e-30

Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113; One of the virulence mechanisms of E coli is the production of toxins which it produces from dedicated machineries called secretion systems. Seven secretion systems have been described, which assemble from 3 to up to more than 20 subunits. These secretion systems derive from or have co-evolved with bacterial organelles such as ABC transporters (type I), type IV pili (type 2), flagella (type 3), or conjugative machines (type IV). The type VI secretion system (T6SS) is present in most pathogens that have contact with animals, plants, or humans. SciN is a lipoprotein tethered to the outer membrane and expressed in the periplasm of E coli and is essential for T6S-dependent secretion of the Hcp-like SciD protein and for biofilm formation.


Pssm-ID: 432786  Cd Length: 120  Bit Score: 107.29  E-value: 1.67e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  45 KTLHLDVTGRAELNTDERENASfsqPVMVWVYQLRDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASLDMPM 124
Cdd:pfam12790   1 TTLDLTLVAAADLNPDENGRPS---PVVVRVYQLKDDSAFNAADFFSLYDDDKAALGADLVAVDEFILRPGETRTLSLPL 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1970150486 125 DERTQFIAVVGLFRAPDmvRNDWKLVLRRDDLEPDKPRVIEASQH 169
Cdd:pfam12790  78 DPGARYVGVVAAYRDLD--NARWRLVIPIPEAGEKNPLTVELDAN 120
VI_chp_3 TIGR03352
type VI secretion lipoprotein, VC_A0113 family; Work by Mougous, et al. (2006), describes ...
 41-164 3.80e-15

type VI secretion lipoprotein, VC_A0113 family; Work by Mougous, et al. (2006), describes IAHP-related loci as a type VI secretion system (). This protein family is associated with type VI secretion loci, although not treated explicitly by Mougous, et al. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274535  Cd Length: 130  Bit Score: 68.05  E-value: 3.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1970150486  41 YKPVKTLHLDVTGRAELNTDERENASfsqPVMVWVYQLRDRKAFDHLLYQQLASEGDNAAGNELLASHSLVVKPGADASL 120
Cdd:TIGR03352   6 PKEPTYVTLTLTAAPDVNPDADGRAS---PVVVRVYELKSDTKFEAADFFALTEDAKKALGDDLIETDEIILLPGEKRKI 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1970150486 121 DMPMDERTQFIAVVGLFRAPDMVRndWKLVLRRDDLEPDKPRVI 164
Cdd:TIGR03352  83 TITLDEGTRYIGVVAAYRDIDNAE--WRVVYKVPPKGKYTIDVM 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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