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Conserved domains on  [gi|1987806660|ref|WP_204209581|]
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MULTISPECIES: TetR/AcrR family transcriptional regulator [Bacillota]

Protein Classification

TetR/AcrR family transcriptional regulator( domain architecture ID 11442015)

TetR/AcrR family transcriptional regulator may control genes involved in one of a variety of processes including antibiotic production, osmotic stress response, efflux pump expression, and multidrug resistance

CATH:  1.10.10.60|1.10.357.10
Gene Ontology:  GO:0003700|GO:0003677|GO:0006355
PubMed:  23602932
SCOP:  4000333

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
3-129 7.39e-12

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


:

Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 60.30  E-value: 7.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1987806660   3 RKGADISKILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLIIQATAYCMAKVEEDF--MAKAPTSFEDI 80
Cdd:COG1309     3 RREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALeeALAAEDPRERL 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1987806660  81 ERFLNEMPHLTAKLHGKKYRFMYQVYSSPKYREQGKEFFKGVNVRYKEY 129
Cdd:COG1309    83 RALLRAYLEFLAENPALARLLLAEAAELPELRAALRALLRRLRALLAEL 131
 
Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
3-129 7.39e-12

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 60.30  E-value: 7.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1987806660   3 RKGADISKILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLIIQATAYCMAKVEEDF--MAKAPTSFEDI 80
Cdd:COG1309     3 RREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALeeALAAEDPRERL 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1987806660  81 ERFLNEMPHLTAKLHGKKYRFMYQVYSSPKYREQGKEFFKGVNVRYKEY 129
Cdd:COG1309    83 RALLRAYLEFLAENPALARLLLAEAAELPELRAALRALLRRLRALLAEL 131
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
11-57 7.87e-06

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 41.24  E-value: 7.87e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1987806660  11 ILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLIIQA 57
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLEAL 47
ScbR_bind_reg NF041196
ScbR family autoregulator-binding transcription factor;
11-67 1.41e-04

ScbR family autoregulator-binding transcription factor;


Pssm-ID: 469100 [Multi-domain]  Cd Length: 191  Bit Score: 40.66  E-value: 1.41e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1987806660  11 ILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLiiqatayCMAKVEE 67
Cdd:NF041196   11 ILEAAAEVFDERGYAAATISDILERAGVTKGALYFHFSSKEAL-------ARAVLEE 60
PRK15008 PRK15008
HTH-type transcriptional regulator RutR; Provisional
 5-55 2.74e-04

HTH-type transcriptional regulator RutR; Provisional


Pssm-ID: 184970 [Multi-domain]  Cd Length: 212  Bit Score: 40.30  E-value: 2.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1987806660   5 GADISKILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLII 55
Cdd:PRK15008   17 SAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYI 67
 
Name Accession Description Interval E-value
AcrR COG1309
DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];
3-129 7.39e-12

DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA [Transcription];


Pssm-ID: 440920 [Multi-domain]  Cd Length: 156  Bit Score: 60.30  E-value: 7.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1987806660   3 RKGADISKILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLIIQATAYCMAKVEEDF--MAKAPTSFEDI 80
Cdd:COG1309     3 RREATRERILDAALELFAEKGYEGTSVRDIAARAGVSKGTLYRHFGSKEELLLAVLERLLEELLAALeeALAAEDPRERL 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1987806660  81 ERFLNEMPHLTAKLHGKKYRFMYQVYSSPKYREQGKEFFKGVNVRYKEY 129
Cdd:COG1309    83 RALLRAYLEFLAENPALARLLLAEAAELPELRAALRALLRRLRALLAEL 131
TetR_N pfam00440
Bacterial regulatory proteins, tetR family;
11-57 7.87e-06

Bacterial regulatory proteins, tetR family;


Pssm-ID: 425684 [Multi-domain]  Cd Length: 47  Bit Score: 41.24  E-value: 7.87e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1987806660  11 ILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLIIQA 57
Cdd:pfam00440   1 ILDAARELFAERGYDATTVREIAKRAGVSKGALYRYFGSKEELLEAL 47
ScbR_bind_reg NF041196
ScbR family autoregulator-binding transcription factor;
11-67 1.41e-04

ScbR family autoregulator-binding transcription factor;


Pssm-ID: 469100 [Multi-domain]  Cd Length: 191  Bit Score: 40.66  E-value: 1.41e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1987806660  11 ILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLiiqatayCMAKVEE 67
Cdd:NF041196   11 ILEAAAEVFDERGYAAATISDILERAGVTKGALYFHFSSKEAL-------ARAVLEE 60
PRK15008 PRK15008
HTH-type transcriptional regulator RutR; Provisional
 5-55 2.74e-04

HTH-type transcriptional regulator RutR; Provisional


Pssm-ID: 184970 [Multi-domain]  Cd Length: 212  Bit Score: 40.30  E-value: 2.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1987806660   5 GADISKILEACFDTFCEYGLENTGMLKLSEASGITNGGLIYHFGSKDNLII 55
Cdd:PRK15008   17 SAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYI 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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