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Conserved domains on  [gi|1993278113|ref|WP_204918641|]
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MarR family transcriptional regulator [Microlunatus panaciterrae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
7-142 7.77e-18

DNA-binding transcriptional regulator, MarR family [Transcription];


:

Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 75.01  E-value: 7.77e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1993278113   7 TDDGDAIDDLAVALVVTCARFVRSSARMAADTEPTAV-WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAV 85
Cdd:COG1846     3 DEPDPAEERLGLLLRRLARALRRALDRALAELGLTPAqFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLV 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1993278113  86 QRVSDPLDGRVSLVSLTEAGRSRLAELRAGVAAALGPRLELLSTDRRAELRGAIETI 142
Cdd:COG1846    83 EREPDPEDRRAVLVRLTEKGRALLEEARPALEALLAELLAGLSEEELEALLRLLRRL 139
 
Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
7-142 7.77e-18

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 75.01  E-value: 7.77e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1993278113   7 TDDGDAIDDLAVALVVTCARFVRSSARMAADTEPTAV-WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAV 85
Cdd:COG1846     3 DEPDPAEERLGLLLRRLARALRRALDRALAELGLTPAqFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLV 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1993278113  86 QRVSDPLDGRVSLVSLTEAGRSRLAELRAGVAAALGPRLELLSTDRRAELRGAIETI 142
Cdd:COG1846    83 EREPDPEDRRAVLVRLTEKGRALLEEARPALEALLAELLAGLSEEELEALLRLLRRL 139
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
44-132 3.81e-16

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 69.16  E-value: 3.81e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1993278113   44 WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAVQRVSDPLDGRVSLVSLTEAGRSRLAELRAGVAAALGPR 123
Cdd:smart00347  13 FLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPSPEDRRSVLVSLTEEGRELIEQLLEARSETLAEL 92


                   ....*....
gi 1993278113  124 LELLSTDRR 132
Cdd:smart00347  93 LAGLTAEEQ 101
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 44-96 2.14e-08

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 47.93  E-value: 2.14e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1993278113  44 WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAVQRVSDPLDGRV 96
Cdd:pfam01047   6 FHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIERSRSPEDRRE 58
 
Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
7-142 7.77e-18

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 75.01  E-value: 7.77e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1993278113   7 TDDGDAIDDLAVALVVTCARFVRSSARMAADTEPTAV-WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAV 85
Cdd:COG1846     3 DEPDPAEERLGLLLRRLARALRRALDRALAELGLTPAqFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKGLV 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1993278113  86 QRVSDPLDGRVSLVSLTEAGRSRLAELRAGVAAALGPRLELLSTDRRAELRGAIETI 142
Cdd:COG1846    83 EREPDPEDRRAVLVRLTEKGRALLEEARPALEALLAELLAGLSEEELEALLRLLRRL 139
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
44-132 3.81e-16

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 69.16  E-value: 3.81e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1993278113   44 WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAVQRVSDPLDGRVSLVSLTEAGRSRLAELRAGVAAALGPR 123
Cdd:smart00347  13 FLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPSPEDRRSVLVSLTEEGRELIEQLLEARSETLAEL 92


                   ....*....
gi 1993278113  124 LELLSTDRR 132
Cdd:smart00347  93 LAGLTAEEQ 101
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 44-96 2.14e-08

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 47.93  E-value: 2.14e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1993278113  44 WRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAVQRVSDPLDGRV 96
Cdd:pfam01047   6 FHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIERSRSPEDRRE 58
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 40-95 4.75e-04

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 36.41  E-value: 4.75e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1993278113  40 PTAVWRAMAILEEHGAMRVSDFAVADRCTQPSATTMLQRLERSGAVQRVSDPLDGR 95
Cdd:pfam12802   4 TPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVEREPSPADRR 59
MntR COG1321
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
49-111 1.85e-03

Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];


Pssm-ID: 440932 [Multi-domain]  Cd Length: 135  Bit Score: 36.33  E-value: 1.85e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1993278113  49 ILEEHGAMRVSDfaVADR--CTQPSATTMLQRLERSGAVQRVSDpldgrvSLVSLTEAGRsRLAE 111
Cdd:COG1321    18 LSEEGGPVRTSD--IAERlgVSPPSVTEMLKKLEEKGLVEYEPY------GGITLTEEGR-ELAL 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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