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Conserved domains on  [gi|1995340955|ref|WP_205532515|]
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methyl-accepting chemotaxis protein [Salmonella enterica]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
180-640 2.30e-73

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 245.32  E-value: 2.30e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 180 NELAAYYSLLNLKEQAGVERALLSNIFSMDRFDDGQFSMFSDVVGQQDAWLTAARSFSTPVQAAELDKSLQSAEATRALE 259
Cdd:COG0840    44 ALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLLAAL 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 260 LRETAFNKAAEGGFGVNPTDWFNLQTQRIETLQKVENRAVDALQEHAALLAHNARVDWQSFLVISLVALLIAIAFAVMVA 339
Cdd:COG0840   124 LAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLS 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 340 RSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRT 418
Cdd:COG0840   204 RSITRPLRELLEVLERIaEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGA 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 419 DEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRV--------------SNEASQSMAEIRSSSEQI 484
Cdd:COG0840   284 EEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVveeavegieeiresVEETAETIEELGESSQEI 363

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 485 SQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELIN--------------QNMDK 550
Cdd:COG0840   364 GEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEeiqseteeaveameEGSEE 443

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 551 IGEGVARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEA 630
Cdd:COG0840   444 VEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEE 523

                         490
                  ....*....|
gi 1995340955 631 MSTLVDRFIV 640
Cdd:COG0840   524 LQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
180-640 2.30e-73

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 245.32  E-value: 2.30e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 180 NELAAYYSLLNLKEQAGVERALLSNIFSMDRFDDGQFSMFSDVVGQQDAWLTAARSFSTPVQAAELDKSLQSAEATRALE 259
Cdd:COG0840    44 ALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLLAAL 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 260 LRETAFNKAAEGGFGVNPTDWFNLQTQRIETLQKVENRAVDALQEHAALLAHNARVDWQSFLVISLVALLIAIAFAVMVA 339
Cdd:COG0840   124 LAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLS 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 340 RSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRT 418
Cdd:COG0840   204 RSITRPLRELLEVLERIaEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGA 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 419 DEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRV--------------SNEASQSMAEIRSSSEQI 484
Cdd:COG0840   284 EEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVveeavegieeiresVEETAETIEELGESSQEI 363

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 485 SQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELIN--------------QNMDK 550
Cdd:COG0840   364 GEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEeiqseteeaveameEGSEE 443

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 551 IGEGVARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEA 630
Cdd:COG0840   444 VEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEE 523

                         490
                  ....*....|
gi 1995340955 631 MSTLVDRFIV 640
Cdd:COG0840   524 LQELVSRFKL 533
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
321-638 5.67e-64

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 220.98  E-value: 5.67e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 321 LVISLVALLIAIAFAVMVarSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVV 399
Cdd:PRK15041  199 VMIVVLAVIFAVWFGIKA--SLVAPMNRLIDSIRHIaGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 400 LRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMAEIRS 479
Cdd:PRK15041  277 IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDIST 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 480 SSEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGVARVT 559
Cdd:PRK15041  357 SSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVE 436

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1995340955 560 ASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEAMSTLVDRF 638
Cdd:PRK15041  437 SAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVF 515
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 392-638 9.62e-53

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 182.10  E-value: 9.62e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  392 EIKSGAVVLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEAS 471
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  472 QSMAEIRSSSEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELIN------ 545
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKeiqeet 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  546 --------QNMDKIGEGVARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQA 617
Cdd:smart00283 161 neavaameESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|.
gi 1995340955  618 ASASQMLDGQSEAMSTLVDRF 638
Cdd:smart00283 241 SAAAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 419-618 4.02e-44

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 156.63  E-value: 4.02e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 419 DEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMAEIRSSSEQISQIVASIDEISFQT 498
Cdd:cd11386     1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 499 NLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGVARVTASGTALKAAAENTGRMKQY 578
Cdd:cd11386    81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1995340955 579 VSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAA 618
Cdd:cd11386   161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
NIT pfam08376
Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in ...
 59-303 2.65e-40

Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.


Pssm-ID: 462453 [Multi-domain]  Cd Length: 227  Bit Score: 146.87  E-value: 2.65e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  59 VHQLQSERGMSAGFIGARGQKfrddlKFRDDLAAQRQLTDKVLATFKRLLTDTNkdlLQGNIAAPLKTFNESIQFLDSTR 138
Cdd:pfam08376   1 VHALQKERGLSAGYLASGGGG-----RFAAELAAQRAATDAALAALRAALAELA---LPARLADRLAALLRALDQLPALR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 139 TAISELTIDSPKASQFYTQTISDVLKFVGGMGHLSTSGSMVNELAAYYSLLNLKEQAGVERALLSNIFSMDRFDDGQFSM 218
Cdd:pfam08376  73 RQVDAGALSALEALAAYTELIAALLDLVDELAAGSPDPELARQLRALAALLRAKEAAGQERALLAAALAAGRFTAAEYRR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 219 FSDVVGQQDAWLTAARSFSTPVQAAELDKSLQSAEATRALELRETAfnkaaeggfgVNPTDWFNLQTQRIETLQKVENRA 298
Cdd:pfam08376 153 FLSLVAAQRAALAEFRAAATPEQRALYDATVTGPAVAAAERLRDRL----------VDAAAWFAASTARIDLLREVEDRL 222


                  ....*
gi 1995340955 299 VDALQ 303
Cdd:pfam08376 223 ADDLA 227
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 370-632 7.76e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 7.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  370 DELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEA 449
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  450 ERLIHSMERDVLEANrvsneasqsmaeirsssEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNL 529
Cdd:TIGR02168  781 EAEIEELEAQIEQLK-----------------EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  530 SQRcAREASQIRELINQNMDKIGEGVARVTAsgtALKAAAENTGRMKQYVSDIARAANEQSLGV----SQVHQALNQLEQ 605
Cdd:TIGR02168  844 EEQ-IEELSEDIESLAAEIEELEELIEELES---ELEALLNERASLEEALALLRSELEELSEELreleSKRSELRRELEE 919

                          250       260
                   ....*....|....*....|....*..
gi 1995340955  606 VTQQNAALVSQAASASQMLDGQSEAMS 632
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERLS 946
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
180-640 2.30e-73

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 245.32  E-value: 2.30e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 180 NELAAYYSLLNLKEQAGVERALLSNIFSMDRFDDGQFSMFSDVVGQQDAWLTAARSFSTPVQAAELDKSLQSAEATRALE 259
Cdd:COG0840    44 ALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALLALLELLLAAL 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 260 LRETAFNKAAEGGFGVNPTDWFNLQTQRIETLQKVENRAVDALQEHAALLAHNARVDWQSFLVISLVALLIAIAFAVMVA 339
Cdd:COG0840   124 LAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLS 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 340 RSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRT 418
Cdd:COG0840   204 RSITRPLRELLEVLERIaEGDLTVRIDVDSKDEIGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGA 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 419 DEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRV--------------SNEASQSMAEIRSSSEQI 484
Cdd:COG0840   284 EEQAASLEETAAAMEELSATVQEVAENAQQAAELAEEASELAEEGGEVveeavegieeiresVEETAETIEELGESSQEI 363

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 485 SQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELIN--------------QNMDK 550
Cdd:COG0840   364 GEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAEATKEIEELIEeiqseteeaveameEGSEE 443

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 551 IGEGVARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEA 630
Cdd:COG0840   444 VEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEE 523

                         490
                  ....*....|
gi 1995340955 631 MSTLVDRFIV 640
Cdd:COG0840   524 LQELVSRFKL 533
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
321-638 5.67e-64

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 220.98  E-value: 5.67e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 321 LVISLVALLIAIAFAVMVarSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVV 399
Cdd:PRK15041  199 VMIVVLAVIFAVWFGIKA--SLVAPMNRLIDSIRHIaGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 400 LRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMAEIRS 479
Cdd:PRK15041  277 IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDIST 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 480 SSEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGVARVT 559
Cdd:PRK15041  357 SSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVE 436

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1995340955 560 ASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEAMSTLVDRF 638
Cdd:PRK15041  437 SAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVF 515
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 317-638 7.35e-64

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 220.65  E-value: 7.35e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 317 WQsFLVISLVALLIAIAFAVMVARSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKS 395
Cdd:PRK15048  192 WQ-LAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIaGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVRE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 396 GAVVLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMA 475
Cdd:PRK15048  271 GSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMH 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 476 EIRSSSEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGV 555
Cdd:PRK15048  351 EIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGS 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 556 ARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEAMSTLV 635
Cdd:PRK15048  431 VLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAV 510


                  ...
gi 1995340955 636 DRF 638
Cdd:PRK15048  511 SAF 513
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
263-640 6.99e-62

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 214.55  E-value: 6.99e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 263 TAFNKAAEGGFGVNPTDWfnlqtqrietlQKVENRAVDALQEHAALLAHNARVdwqSFLVISLVALLIAIAFAVMVARSI 342
Cdd:PRK09793  149 TAPVQGSQNAFDVNFEAW-----------QLEINHVLEAASAQSQRNYQISAL---VFISMIIVAAIYISSALWWTRKMI 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 343 QQQL---NGTLKTIAemDGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRTD 419
Cdd:PRK09793  215 VQPLaiiGSHFDSIA--AGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTE 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 420 EQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMAEIRSSSEQISQIVASIDEISFQTN 499
Cdd:PRK09793  293 QQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQAGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTN 372

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 500 LLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGVARVTASGTALKAAAENTGRMKQYV 579
Cdd:PRK09793  373 ILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMTDIVSSVTRVNDIM 452

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1995340955 580 SDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEAMSTLVDRFIV 640
Cdd:PRK09793  453 GEIASASEEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 392-638 9.62e-53

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 182.10  E-value: 9.62e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  392 EIKSGAVVLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEAS 471
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  472 QSMAEIRSSSEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELIN------ 545
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKeiqeet 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  546 --------QNMDKIGEGVARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQA 617
Cdd:smart00283 161 neavaameESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|.
gi 1995340955  618 ASASQMLDGQSEAMSTLVDRF 638
Cdd:smart00283 241 SAAAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 419-618 4.02e-44

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 156.63  E-value: 4.02e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 419 DEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMAEIRSSSEQISQIVASIDEISFQT 498
Cdd:cd11386     1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 499 NLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGVARVTASGTALKAAAENTGRMKQY 578
Cdd:cd11386    81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1995340955 579 VSDIARAANEQSLGVSQVHQALNQLEQVTQQNAALVSQAA 618
Cdd:cd11386   161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
NIT pfam08376
Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in ...
 59-303 2.65e-40

Nitrate and nitrite sensing; The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.


Pssm-ID: 462453 [Multi-domain]  Cd Length: 227  Bit Score: 146.87  E-value: 2.65e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  59 VHQLQSERGMSAGFIGARGQKfrddlKFRDDLAAQRQLTDKVLATFKRLLTDTNkdlLQGNIAAPLKTFNESIQFLDSTR 138
Cdd:pfam08376   1 VHALQKERGLSAGYLASGGGG-----RFAAELAAQRAATDAALAALRAALAELA---LPARLADRLAALLRALDQLPALR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 139 TAISELTIDSPKASQFYTQTISDVLKFVGGMGHLSTSGSMVNELAAYYSLLNLKEQAGVERALLSNIFSMDRFDDGQFSM 218
Cdd:pfam08376  73 RQVDAGALSALEALAAYTELIAALLDLVDELAAGSPDPELARQLRALAALLRAKEAAGQERALLAAALAAGRFTAAEYRR 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 219 FSDVVGQQDAWLTAARSFSTPVQAAELDKSLQSAEATRALELRETAfnkaaeggfgVNPTDWFNLQTQRIETLQKVENRA 298
Cdd:pfam08376 153 FLSLVAAQRAALAEFRAAATPEQRALYDATVTGPAVAAAERLRDRL----------VDAAAWFAASTARIDLLREVEDRL 222


                  ....*
gi 1995340955 299 VDALQ 303
Cdd:pfam08376 223 ADDLA 227
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 461-607 3.51e-32

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 122.54  E-value: 3.51e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 461 LEANRVSNEASQSMAEIRSSSEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNLSQRCAREASQI 540
Cdd:pfam00015  12 QDGGKEVANVVGQMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERSAQAAKEI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 541 RELIN--------------QNMDKIGEGVARVTASGTALKAAAENTGRMKQYVSDIARAANEQSLGVSQVHQALNQLEQV 606
Cdd:pfam00015  92 EALIIeiqkqtndstasieSTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQAVARMDQV 171


                  .
gi 1995340955 607 T 607
Cdd:pfam00015 172 T 172
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 319-557 2.46e-10

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 63.06  E-value: 2.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 319 SFLVISLVALLIAIAFAVMVARSIQQQLNGTLKTIAE-----MDGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEI 393
Cdd:COG5000     6 LFLLLLLLIALLLLLLALWLALLLARRLTRPLRRLAEatravAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 394 KSGAV----VLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNE 469
Cdd:COG5000    86 EERRRyletILENLPAGVIVLDADGRITLANPAAERLLGIPLEELIGKPLEELLPELDLAELLREALERGWQEEIELTRD 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 470 ASQSMAeIRSSSEQISQIVASIDEISfqtnllalnAAVEAARAGELGKGFAVVATEVRN-----------LSQRCAREAS 538
Cdd:COG5000   166 GRRTLL-VRASPLRDDGYVIVFDDIT---------ELLRAERLAAWGELARRIAHEIKNpltpiqlsaerLRRKLADKLE 235

                         250
                  ....*....|....*....
gi 1995340955 539 QIRELINQNMDKIGEGVAR 557
Cdd:COG5000   236 EDREDLERALDTIIRQVDR 254
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
107-640 5.58e-05

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 46.26  E-value: 5.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 107 LLTDTNKDLLQGNIAAPLKTFNESIQFLDSTRTAISELTIDSPKASQFYTQTISDVLKFVGGMGHLSTSGSMVNELAAYY 186
Cdd:COG2770     1 LLLLLLALLLLLLLLLLLLLLAGALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 187 SLLNLKEQAGVERALLSNIFSMDRFDDGQFSMFSDVVGQQDAWLTAARSFSTPVQAAELDKSLQSAEATRALELRETAFN 266
Cdd:COG2770    81 LLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLAL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 267 KAAEGGFGVNPTDWFNLQTQRIETLQKVENRAVDALQEHAALLAHNARVDWQSFLVISLVALLIAIAFAVMVARSIQQQL 346
Cdd:COG2770   161 AAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 347 NGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRTDEQAASI 425
Cdd:COG2770   241 RRLAEAARRIaAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLAL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 426 VETAASMEQISTAITQTADNASEAERLIHSMERDVLEANRVSNEASQSMAEIRSSSEQISQIVASIDEISFQTNLLALNA 505
Cdd:COG2770   321 LLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAA 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 506 AVEAARAGELGKGFAVVATEVRNLSQRCAREASQIRELINQNMDKIGEGVARVTASGTALKAAAENTGRMKQYVSDIARA 585
Cdd:COG2770   401 ALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLL 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1995340955 586 ANEQSLGVSQVHQALNQLEQVTQQNAALVSQAASASQMLDGQSEAMSTLVDRFIV 640
Cdd:COG2770   481 LAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVAEELLEL 535
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 319-546 6.98e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 6.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 319 SFLVISLVALLIAIAFAVmVARSIQQQLNGTLKTIAEMDGDLTRRLDVPGS--DELSALNRAYNQAIENIQHIVQEIKSG 396
Cdd:COG4942     3 KLLLLALLLALAAAAQAD-AAAEAEAELEQLQQEIAELEKELAALKKEEKAllKQLAALERRIAALARRIRALEQELAAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 397 AVVLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEAERLIHSMerdvleaNRVSNEASQSMAE 476
Cdd:COG4942    82 EAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL-------KYLAPARREQAEE 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955 477 IRSSSEQISQIVASIDEIsfQTNLLALNAAVEAARAgELGKGFAVVATEVRNLSQRCAREASQIRELINQ 546
Cdd:COG4942   155 LRADLAELAALRAELEAE--RAELEALLAELEEERA-ALEALKAERQKLLARLEKELAELAAELAELQQE 221
HAMP pfam00672
HAMP domain;
337-388 2.43e-04

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 39.14  E-value: 2.43e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1995340955 337 MVARSIQQQLNGTLKTIAEM-DGDLTRRLDVPGSDELSALNRAYNQAIENIQH 388
Cdd:pfam00672   1 LLARRILRPLRRLAEAARRIaSGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
344-391 2.77e-04

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 39.15  E-value: 2.77e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 1995340955  344 QQLNGTLKTIAemDGDLTRRLDVPGSDELSALNRAYNQAIENIQHIVQ 391
Cdd:smart00304   8 RRLAEAAQRIA--DGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 344-386 1.88e-03

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 36.27  E-value: 1.88e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1995340955 344 QQLNGTLKTIAEmdGDLTRRLDVPGSDELSALNRAYNQAIENI 386
Cdd:cd06225     5 RRLTEAARRIAE--GDLDVRVPVRSKDEIGELARAFNQMAERL 45
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 370-632 7.76e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 7.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  370 DELSALNRAYNQAIENIQHIVQEIKSGAVVLRSASSDIAAGNQDLAQRTDEQAASIVETAASMEQISTAITQTADNASEA 449
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  450 ERLIHSMERDVLEANrvsneasqsmaeirsssEQISQIVASIDEISFQTNLLALNAAVEAARAGELGKGFAVVATEVRNL 529
Cdd:TIGR02168  781 EAEIEELEAQIEQLK-----------------EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1995340955  530 SQRcAREASQIRELINQNMDKIGEGVARVTAsgtALKAAAENTGRMKQYVSDIARAANEQSLGV----SQVHQALNQLEQ 605
Cdd:TIGR02168  844 EEQ-IEELSEDIESLAAEIEELEELIEELES---ELEALLNERASLEEALALLRSELEELSEELreleSKRSELRRELEE 919

                          250       260
                   ....*....|....*....|....*..
gi 1995340955  606 VTQQNAALVSQAASASQMLDGQSEAMS 632
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERLS 946
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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