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Conserved domains on  [gi|1997574809|ref|WP_206161172|]
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PTS transporter subunit EIIB, partial [Staphylococcus sp. EG-SA-2]

Protein Classification

PtsG2 family protein( domain architecture ID 10003285)

PtsG2 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PtsG2 COG1264
Phosphotransferase system IIB components [Carbohydrate transport and metabolism];
32-107 4.36e-30

Phosphotransferase system IIB components [Carbohydrate transport and metabolism];


:

Pssm-ID: 440876 [Multi-domain]  Cd Length: 76  Bit Score: 102.12  E-value: 4.36e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1997574809  32 QHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGkHSTQVIVGTHVQQVADEIEKHL 107
Cdd:COG1264     2 ELAKDILEALGGKENIVSVDHCATRLRVTVKDPSKVDEAALKKLGVKGVVKNG-GQVQVIIGPGVDKVADEIEKLL 76
 
Name Accession Description Interval E-value
PtsG2 COG1264
Phosphotransferase system IIB components [Carbohydrate transport and metabolism];
32-107 4.36e-30

Phosphotransferase system IIB components [Carbohydrate transport and metabolism];


Pssm-ID: 440876 [Multi-domain]  Cd Length: 76  Bit Score: 102.12  E-value: 4.36e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1997574809  32 QHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGkHSTQVIVGTHVQQVADEIEKHL 107
Cdd:COG1264     2 ELAKDILEALGGKENIVSVDHCATRLRVTVKDPSKVDEAALKKLGVKGVVKNG-GQVQVIIGPGVDKVADEIEKLL 76
PTS_IIB_glc cd00212
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ...
 31-107 3.55e-25

PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation


Pssm-ID: 238130 [Multi-domain]  Cd Length: 78  Bit Score: 89.90  E-value: 3.55e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1997574809  31 HQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHV-QQVADEIEKHL 107
Cdd:cd00212     1 EQLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLGGVKGVVKNGGQYQVIIGPGVaDVYKEAIKLLG 78
PRK10110 PRK10110
PTS maltose transporter subunit IICB;
37-104 2.65e-20

PTS maltose transporter subunit IICB;


Pssm-ID: 182245 [Multi-domain]  Cd Length: 530  Bit Score: 84.01  E-value: 2.65e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1997574809  37 ILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHVQQVADEIE 104
Cdd:PRK10110  455 ILEALGGADNIVSLDNCITRLRLSVKDMSLVDVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMA 522
PTS-II-BC-sucr TIGR01996
PTS system, sucrose-specific IIBC component; This model represents the fused enzyme II B and C ...
 29-105 4.31e-16

PTS system, sucrose-specific IIBC component; This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).


Pssm-ID: 131051  Cd Length: 461  Bit Score: 71.95  E-value: 4.31e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1997574809  29 KYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKI-KNAGAVGVTVNGKHsTQVIVGT-HVQQVADEIEK 105
Cdd:TIGR01996   1 NYQQVAKEILELLGGKDNIVSVAHCATRLRLVLKDESKIDKKAIeNLDGVKGTFFNSGQ-YQIIIGTgVVNKVYDEIVK 78
PTS_EIIB pfam00367
phosphotransferase system, EIIB;
36-66 3.09e-13

phosphotransferase system, EIIB;


Pssm-ID: 459785 [Multi-domain]  Cd Length: 32  Bit Score: 58.53  E-value: 3.09e-13
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1997574809  36 QILEGLGGQENIVNLTNCATRLRLELKDTSI 66
Cdd:pfam00367   2 EILEALGGKENIKSVDHCATRLRLTVKDESK 32
 
Name Accession Description Interval E-value
PtsG2 COG1264
Phosphotransferase system IIB components [Carbohydrate transport and metabolism];
32-107 4.36e-30

Phosphotransferase system IIB components [Carbohydrate transport and metabolism];


Pssm-ID: 440876 [Multi-domain]  Cd Length: 76  Bit Score: 102.12  E-value: 4.36e-30
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1997574809  32 QHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGkHSTQVIVGTHVQQVADEIEKHL 107
Cdd:COG1264     2 ELAKDILEALGGKENIVSVDHCATRLRVTVKDPSKVDEAALKKLGVKGVVKNG-GQVQVIIGPGVDKVADEIEKLL 76
PTS_IIB_glc cd00212
PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: ...
 31-107 3.55e-25

PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation


Pssm-ID: 238130 [Multi-domain]  Cd Length: 78  Bit Score: 89.90  E-value: 3.55e-25
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1997574809  31 HQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHV-QQVADEIEKHL 107
Cdd:cd00212     1 EQLAKDILEALGGKENIVSLDHCATRLRLTVKDESKVDEAALKKLGGVKGVVKNGGQYQVIIGPGVaDVYKEAIKLLG 78
PRK10110 PRK10110
PTS maltose transporter subunit IICB;
37-104 2.65e-20

PTS maltose transporter subunit IICB;


Pssm-ID: 182245 [Multi-domain]  Cd Length: 530  Bit Score: 84.01  E-value: 2.65e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1997574809  37 ILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHVQQVADEIE 104
Cdd:PRK10110  455 ILEALGGADNIVSLDNCITRLRLSVKDMSLVDVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMA 522
PTS-II-BC-sucr TIGR01996
PTS system, sucrose-specific IIBC component; This model represents the fused enzyme II B and C ...
 29-105 4.31e-16

PTS system, sucrose-specific IIBC component; This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).


Pssm-ID: 131051  Cd Length: 461  Bit Score: 71.95  E-value: 4.31e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1997574809  29 KYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKI-KNAGAVGVTVNGKHsTQVIVGT-HVQQVADEIEK 105
Cdd:TIGR01996   1 NYQQVAKEILELLGGKDNIVSVAHCATRLRLVLKDESKIDKKAIeNLDGVKGTFFNSGQ-YQIIIGTgVVNKVYDEIVK 78
PTS-II-ABC-beta TIGR01995
PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS ...
 30-103 5.96e-16

PTS system, beta-glucoside-specific IIABC component; This model represents a family of PTS enzyme II proteins in which all three domains are found in the same polypeptide chain and which appear to have a broad specificity for beta-glucosides including salicin (beta-D-glucose-1-salicylate) and arbutin (Hydroquinone-O-beta-D-glucopyranoside). These are distinct from the closely related sucrose-specific and trehalose-specific PTS transporters.


Pssm-ID: 273919 [Multi-domain]  Cd Length: 610  Bit Score: 71.61  E-value: 5.96e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1997574809  30 YHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHVQQVADEI 103
Cdd:TIGR01995   1 YQDLAKAIIENVGGKENIESVTHCATRLRFTLKDDAKADTEKLKKISGVITVVKSGGQYQVVIGNDVNDVYQAL 74
PRK09824 PRK09824
PTS system beta-glucoside-specific transporter subunits IIABC; Provisional
 29-99 1.29e-15

PTS system beta-glucoside-specific transporter subunits IIABC; Provisional


Pssm-ID: 236627 [Multi-domain]  Cd Length: 627  Bit Score: 70.90  E-value: 1.29e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1997574809  29 KYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHVQQV 99
Cdd:PRK09824    2 EYTELAREIVAGVGGADNIVSLMHCATRLRFKLKDNSKAQAEVLKKNPGVIMVVESGGQFQVVIGNHVADV 72
PRK11089 PRK11089
PTS system glucose-specific transporter subunits IIBC; Provisional
 20-94 5.03e-14

PTS system glucose-specific transporter subunits IIBC; Provisional


Pssm-ID: 182955 [Multi-domain]  Cd Length: 477  Bit Score: 66.28  E-value: 5.03e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1997574809  20 PG----ENDIKQSKYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKhSTQVIVGT 94
Cdd:PRK11089  384 PGredeTEDAKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVVAGS-GVQAIFGT 461
PTS_EIIB pfam00367
phosphotransferase system, EIIB;
36-66 3.09e-13

phosphotransferase system, EIIB;


Pssm-ID: 459785 [Multi-domain]  Cd Length: 32  Bit Score: 58.53  E-value: 3.09e-13
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1997574809  36 QILEGLGGQENIVNLTNCATRLRLELKDTSI 66
Cdd:pfam00367   2 EILEALGGKENIKSVDHCATRLRLTVKDESK 32
PRK10255 PRK10255
PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional
 14-105 5.87e-12

PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional


Pssm-ID: 182338 [Multi-domain]  Cd Length: 648  Bit Score: 60.27  E-value: 5.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997574809  14 VKDNIAPGENDIKQSKYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVG 93
Cdd:PRK10255  373 EDEIVTEEANSNTEEGLTQLATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDAMCKRLGASGVVKLNKQTIQVIVG 452

                          90
                  ....*....|..
gi 1997574809  94 THVQQVADEIEK 105
Cdd:PRK10255  453 AKAESIGDAMKK 464
PRK09702 PRK09702
PTS sugar transporter subunit IIB;
33-104 1.52e-11

PTS sugar transporter subunit IIB;


Pssm-ID: 77355 [Multi-domain]  Cd Length: 161  Bit Score: 57.41  E-value: 1.52e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1997574809  33 HAIQILEGLGGQENIVNLTNCATRLRLELKDTS-IIDQQKIKNAGAVGVTVNGKhSTQVIVGTHVQQVADEIE 104
Cdd:PRK09702   72 QAAGILQALGGVGNISSINNCATRLRIALHDMSqTLDDEVFKKLGAHGVFRSGD-AIQVIIGLHVSQLREQLD 143
PRK09796 PRK09796
PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional
 30-105 5.48e-11

PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional


Pssm-ID: 182081  Cd Length: 472  Bit Score: 57.50  E-value: 5.48e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997574809  30 YHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKN-AGAVGVtVNGKHSTQVIVGTHVQQVADEIEK 105
Cdd:PRK09796    5 YAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDALIDSPTLKTiPGVLGV-VRSDNQCQVIIGNTVSQAFQEVVS 80
murP PRK09586
PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed
 36-107 1.10e-10

PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed


Pssm-ID: 181971 [Multi-domain]  Cd Length: 476  Bit Score: 56.61  E-value: 1.10e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1997574809  36 QILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKN-AGAVGVtVNGKHSTQVIVGTHVQQVADEIEKHL 107
Cdd:PRK09586   11 TILTRVGGPGNIASCGNCMTRLRLTLHDSSLVDPAAIKTiEGVKGV-ILSDDQVQVVLGPGKAQRAAKAMNEL 82
PRK11007 PRK11007
PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional
 26-99 1.62e-09

PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional


Pssm-ID: 182896  Cd Length: 473  Bit Score: 53.15  E-value: 1.62e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1997574809  26 KQSKYHQHAI-QILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTHVQQV 99
Cdd:PRK11007    1 MMSKINQQDIdRLIELVGGRENIATVSHCITRLRFVLNDPANADPKEIEQLPMVKGCFTNAGQFQVVIGTEVGDY 75
EIIB_glc TIGR00826
PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) ...
 37-93 2.09e-09

PTS system, glucose-like IIB component; The PTS Glucose-Glucoside (Glc) Family (TC 4.A.1) Bacterial PTS transporters transport and concomitantly phosphorylate their sugar substrates, and typically consist of multiple subunits or protein domains. The Glc family includes permeases specific for glucose, N-acetylglucosamine and a large variety of a- and b-glucosides. However, not all b-glucoside PTS permeases are in this class, as the cellobiose (Cel) b-glucoside PTS permease is in the Lac family (TC #4.A.3). These permeases show limited sequence similarity with members of the Fru family (TC #4.A.2). Several of the E. coli PTS permeases in the Glc family lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). Most of these permeases have the B and C domains linked together in a single polypeptide chain, and a cysteyl residue in the IIB domain is phosphorylated by direct phosphoryl transfer from IIAglc(his~P). Those permeases which lack a IIA domain include the maltose (Mal), arbutin-salicin-cellobiose (ASC), trehalose (Tre), putative glucoside (Glv) and sucrose (Scr) permeases of E. coli . Most, but not all Scr permeases of other bacteria also lack a IIA domain. This model is specific for the IIB domain of the Glc family PTS transporters. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids, Signal transduction, PTS]


Pssm-ID: 273288 [Multi-domain]  Cd Length: 88  Bit Score: 50.05  E-value: 2.09e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1997574809  37 ILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGkHSTQVIVG 93
Cdd:TIGR00826  33 QIQALGGTGNVNKVDACITRLRVGVADVSKVDDAVLKKLGAHGVNPLQ-RAVQVISG 88
PRK14905 PRK14905
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ...
 24-107 6.59e-09

triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional


Pssm-ID: 184898 [Multi-domain]  Cd Length: 355  Bit Score: 51.57  E-value: 6.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997574809  24 DIKQSKYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQQKIKNAGAVGVTVNGKHSTQVIVGTH-VQQVADE 102
Cdd:PRK14905  268 DPIIHKFSEIAIQLIDHLGGKDNISALTHCASRIRVMLRNDGHIDKSAIEKIDCVKGLFSIANQYQIILGAGiVEKIHEE 347


                  ....*
gi 1997574809 103 IEKHL 107
Cdd:PRK14905  348 MKALL 352
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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