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Conserved domains on  [gi|1997949837|ref|WP_206383111|]
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type III pantothenate kinase, partial [Acidithiobacillus sp. PG05]

Protein Classification

CoaX family protein( domain architecture ID 10003942)

CoaX family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CoaX COG1521
Pantothenate kinase type III [Coenzyme transport and metabolism];
13-166 8.27e-48

Pantothenate kinase type III [Coenzyme transport and metabolism];


:

Pssm-ID: 441130 [Multi-domain]  Cd Length: 250  Bit Score: 155.32  E-value: 8.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  13 VPHDYHPPESLGFDRRCCLLAAAMDYpGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLN 91
Cdd:COG1521    92 LKNAYDNPEELGADRIANAVAARELY-GGPLLVVDFGTATTFDVVdADGEYLGGAIAPGLGLSLEALHQRTAKLPLVELE 170

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997949837  92 APAEMLGNDTSNAIQAGVIHLFADALRGAITDFRQ-YSPQARILITGGDAERWQPGIAGSL-YQPHLLLRGFYLWIR 166
Cdd:COG1521   171 KPPSVIGKNTVEAIQSGVVYGYAGLIEGLIERIKEeLGEDPKVIATGGDAPLLAPELKTIDiVDPDLVLEGLRLIYE 247
 
Name Accession Description Interval E-value
CoaX COG1521
Pantothenate kinase type III [Coenzyme transport and metabolism];
13-166 8.27e-48

Pantothenate kinase type III [Coenzyme transport and metabolism];


Pssm-ID: 441130 [Multi-domain]  Cd Length: 250  Bit Score: 155.32  E-value: 8.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  13 VPHDYHPPESLGFDRRCCLLAAAMDYpGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLN 91
Cdd:COG1521    92 LKNAYDNPEELGADRIANAVAARELY-GGPLLVVDFGTATTFDVVdADGEYLGGAIAPGLGLSLEALHQRTAKLPLVELE 170

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997949837  92 APAEMLGNDTSNAIQAGVIHLFADALRGAITDFRQ-YSPQARILITGGDAERWQPGIAGSL-YQPHLLLRGFYLWIR 166
Cdd:COG1521   171 KPPSVIGKNTVEAIQSGVVYGYAGLIEGLIERIKEeLGEDPKVIATGGDAPLLAPELKTIDiVDPDLVLEGLRLIYE 247
ASKHA_NBD_PanK-III cd24015
nucleotide-binding domain (NBD) of type III pantothenate kinase (PanK-III) and similar ...
 16-164 7.58e-45

nucleotide-binding domain (NBD) of type III pantothenate kinase (PanK-III) and similar proteins; PanK (EC 2.7.1.33), also called pantothenic acid kinase, is the first enzyme in the Coenzyme A (CoA) biosynthetic pathway. It catalyzes the phosphorylation of pantothenate (vitamin B5) to form 4'-phosphopantothenate at the expense of a molecule of adenosine triphosphate (ATP), which is the rate-limiting step in CoA biosynthesis. It cannot utilize a phosphoryl donor other than ATP. Three distinct types of PanK have been identified, PanK-I, PanK-II and PanK-III. The model corresponds to PanK-III that belongs to the ASKHA (Acetate and Sugar Kinases/Hsc70/Actin) superfamily of phosphotransferases, all members of which share a common characteristic five-stranded beta sheet occurring in both the N- and C-terminal domains.


Pssm-ID: 466865 [Multi-domain]  Cd Length: 241  Bit Score: 147.41  E-value: 7.58e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  16 DYHPPESLGFDRrCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAPA 94
Cdd:cd24015    91 AYDNPKELGADR-LANAVAAAKLYGRPVIVVDFGTATTIDLVdAEGEFLGGAIAPGIELSLKALHQRTAKLPSVELIKPK 169

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1997949837  95 EMLGNDTSNAIQAGVIHLFADALRGAITDFRQ-YSPQARILITGGDAERWQPGI-AGSLYQPHLLLRGFYLW 164
Cdd:cd24015   170 KVIGKNTEEAIQSGVFYGYAGLIEGIIERLKKeLGGDAKVILTGGDAKLVAPYLePIDIYDPDLTLKGLKLI 241
PRK13320 PRK13320
type III pantothenate kinase;
16-160 1.47e-40

type III pantothenate kinase;


Pssm-ID: 237348 [Multi-domain]  Cd Length: 244  Bit Score: 136.53  E-value: 1.47e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  16 DYHPPESLGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAPA 94
Cdd:PRK13320   89 DYDTPETLGADRLALCAGARYLFPGKNVLAIDAGTAITYDVLdSEGVYLGGLISPGLEMRFKALHEFTARLPLVTIEGPI 168

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997949837  95 EMLGNDTSNAIQAGVIHLFADALRGAITDFRQYSPQARILITGGDAERWQPGIAGSLY-QPHLLLRG 160
Cdd:PRK13320  169 PLIGRSTEECIRSGVVWGCVAEIEGLIEAYKSKLPELLVILTGGDAPFLASRLKNTIFaDEHAVLKG 235
Pan_kinase pfam03309
Type III pantothenate kinase; Type III pantothenate kinase catalyzes the phosphorylation of ...
 13-121 1.59e-32

Type III pantothenate kinase; Type III pantothenate kinase catalyzes the phosphorylation of pantothenate (Pan), the first step in the universal pathway of CoA biosynthesis.


Pssm-ID: 460881 [Multi-domain]  Cd Length: 205  Bit Score: 114.97  E-value: 1.59e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  13 VPHDYHPPESLGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLN 91
Cdd:pfam03309  94 LRNRYDNPKELGADRWVNAVAARELYPGKPLIVVDFGTATTFDAVsADGEYLGGAIAPGIGLSLDALAQGTAKLPRVEIT 173

                          90       100       110
                  ....*....|....*....|....*....|
gi 1997949837  92 APAEMLGNDTSNAIQAGVIHLFADALRGAI 121
Cdd:pfam03309 174 RPGSVIGKNTVEAIQSGILYGYAGLVEGII 203
baf TIGR00671
pantothenate kinase, type III; This model describes a family of proteins found in a single ...
 14-160 7.03e-28

pantothenate kinase, type III; This model describes a family of proteins found in a single copy in at least ten different early completed bacterial genomes. The only characterized member of the family is Bvg accessory factor (Baf), a protein required, in addition to the regulatory operon bvgAS, for heterologous transcription of the Bordetella pertussis toxin operon (ptx) in E. coli. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 273210 [Multi-domain]  Cd Length: 243  Bit Score: 103.71  E-value: 7.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  14 PHDYHPPESLGFDRRCCLLAAAMDYpGQDSIVIDMGTAITIDLLAG-GHFRGGRILPGIAMSLRGLHEGTALLPEVVLNA 92
Cdd:TIGR00671  90 PNLYKSPKELGIDRVANALAAIKFY-GFNVVVVDAGTALTIDLVDQeGKFLGGAIAPGLGISLHALKDRAAALPKFEIAR 168

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1997949837  93 PAEMLGNDTSNAIQAGVIHLFADALRGAITDFRQYSPQ-ARILITGGDAERWQPGIAGSLYQPHLLLRG 160
Cdd:TIGR00671 169 PDEVLGKSTREAVQSGAVYGVLGLIQGLLKDWKKYFKRkFAVVITGGDGKYLSAFLPFSIYDPHLTVEG 237
 
Name Accession Description Interval E-value
CoaX COG1521
Pantothenate kinase type III [Coenzyme transport and metabolism];
13-166 8.27e-48

Pantothenate kinase type III [Coenzyme transport and metabolism];


Pssm-ID: 441130 [Multi-domain]  Cd Length: 250  Bit Score: 155.32  E-value: 8.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  13 VPHDYHPPESLGFDRRCCLLAAAMDYpGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLN 91
Cdd:COG1521    92 LKNAYDNPEELGADRIANAVAARELY-GGPLLVVDFGTATTFDVVdADGEYLGGAIAPGLGLSLEALHQRTAKLPLVELE 170

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997949837  92 APAEMLGNDTSNAIQAGVIHLFADALRGAITDFRQ-YSPQARILITGGDAERWQPGIAGSL-YQPHLLLRGFYLWIR 166
Cdd:COG1521   171 KPPSVIGKNTVEAIQSGVVYGYAGLIEGLIERIKEeLGEDPKVIATGGDAPLLAPELKTIDiVDPDLVLEGLRLIYE 247
ASKHA_NBD_PanK-III cd24015
nucleotide-binding domain (NBD) of type III pantothenate kinase (PanK-III) and similar ...
 16-164 7.58e-45

nucleotide-binding domain (NBD) of type III pantothenate kinase (PanK-III) and similar proteins; PanK (EC 2.7.1.33), also called pantothenic acid kinase, is the first enzyme in the Coenzyme A (CoA) biosynthetic pathway. It catalyzes the phosphorylation of pantothenate (vitamin B5) to form 4'-phosphopantothenate at the expense of a molecule of adenosine triphosphate (ATP), which is the rate-limiting step in CoA biosynthesis. It cannot utilize a phosphoryl donor other than ATP. Three distinct types of PanK have been identified, PanK-I, PanK-II and PanK-III. The model corresponds to PanK-III that belongs to the ASKHA (Acetate and Sugar Kinases/Hsc70/Actin) superfamily of phosphotransferases, all members of which share a common characteristic five-stranded beta sheet occurring in both the N- and C-terminal domains.


Pssm-ID: 466865 [Multi-domain]  Cd Length: 241  Bit Score: 147.41  E-value: 7.58e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  16 DYHPPESLGFDRrCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAPA 94
Cdd:cd24015    91 AYDNPKELGADR-LANAVAAAKLYGRPVIVVDFGTATTIDLVdAEGEFLGGAIAPGIELSLKALHQRTAKLPSVELIKPK 169

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1997949837  95 EMLGNDTSNAIQAGVIHLFADALRGAITDFRQ-YSPQARILITGGDAERWQPGI-AGSLYQPHLLLRGFYLW 164
Cdd:cd24015   170 KVIGKNTEEAIQSGVFYGYAGLIEGIIERLKKeLGGDAKVILTGGDAKLVAPYLePIDIYDPDLTLKGLKLI 241
PRK13320 PRK13320
type III pantothenate kinase;
16-160 1.47e-40

type III pantothenate kinase;


Pssm-ID: 237348 [Multi-domain]  Cd Length: 244  Bit Score: 136.53  E-value: 1.47e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  16 DYHPPESLGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAPA 94
Cdd:PRK13320   89 DYDTPETLGADRLALCAGARYLFPGKNVLAIDAGTAITYDVLdSEGVYLGGLISPGLEMRFKALHEFTARLPLVTIEGPI 168

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997949837  95 EMLGNDTSNAIQAGVIHLFADALRGAITDFRQYSPQARILITGGDAERWQPGIAGSLY-QPHLLLRG 160
Cdd:PRK13320  169 PLIGRSTEECIRSGVVWGCVAEIEGLIEAYKSKLPELLVILTGGDAPFLASRLKNTIFaDEHAVLKG 235
Pan_kinase pfam03309
Type III pantothenate kinase; Type III pantothenate kinase catalyzes the phosphorylation of ...
 13-121 1.59e-32

Type III pantothenate kinase; Type III pantothenate kinase catalyzes the phosphorylation of pantothenate (Pan), the first step in the universal pathway of CoA biosynthesis.


Pssm-ID: 460881 [Multi-domain]  Cd Length: 205  Bit Score: 114.97  E-value: 1.59e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  13 VPHDYHPPESLGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLN 91
Cdd:pfam03309  94 LRNRYDNPKELGADRWVNAVAARELYPGKPLIVVDFGTATTFDAVsADGEYLGGAIAPGIGLSLDALAQGTAKLPRVEIT 173

                          90       100       110
                  ....*....|....*....|....*....|
gi 1997949837  92 APAEMLGNDTSNAIQAGVIHLFADALRGAI 121
Cdd:pfam03309 174 RPGSVIGKNTVEAIQSGILYGYAGLVEGII 203
PRK13318 PRK13318
type III pantothenate kinase;
20-163 1.81e-32

type III pantothenate kinase;


Pssm-ID: 237347 [Multi-domain]  Cd Length: 258  Bit Score: 116.01  E-value: 1.81e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  20 PESLGFDRRCCLLAAAMDYPGqDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAPAEMLG 98
Cdd:PRK13318  104 PKEVGADRIVNAVAAYELYGG-PLIVVDFGTATTFDVVsAKGEYLGGVIAPGINISADALFQRAAKLPRVEITKPDSVIG 182

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1997949837  99 NDTSNAIQAGVIHLFADALRGAITDFRQYSPQ-ARILITGGDAerwqPGIAGSL-----YQPHLLLRGFYL 163
Cdd:PRK13318  183 KNTVEAMQSGIYYGYVGLVEGIVKRIKEELGKdPKVIATGGLA----PLFAEESdtidiVDPDLTLKGLRL 249
PRK13331 PRK13331
pantothenate kinase; Reviewed
 22-160 1.17e-28

pantothenate kinase; Reviewed


Pssm-ID: 237353 [Multi-domain]  Cd Length: 251  Bit Score: 105.90  E-value: 1.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  22 SLGFDRRCCLLAAAMDYpGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAP-AEMLGN 99
Cdd:PRK13331   95 TLGIDRALALWGAGQTY-GFPCLVIDAGTALTFTGVdSDRTLVGGAILPGLGLQLRSLADKTAALPQVELPPPlPPRWAT 173

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1997949837 100 DTSNAIQAGVIHLFADALRGAITDFRQYSPQARILITGGDAER----WQ---PGIAGSLYQ-PHLLLRG 160
Cdd:PRK13331  174 NTQEAIQSGVIYTILAGLRDFIEDWLSLFPDGKIVLTGGDGELlhnyLQdldPELAQRLRVdPNLIFWG 242
baf TIGR00671
pantothenate kinase, type III; This model describes a family of proteins found in a single ...
 14-160 7.03e-28

pantothenate kinase, type III; This model describes a family of proteins found in a single copy in at least ten different early completed bacterial genomes. The only characterized member of the family is Bvg accessory factor (Baf), a protein required, in addition to the regulatory operon bvgAS, for heterologous transcription of the Bordetella pertussis toxin operon (ptx) in E. coli. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pantothenate and coenzyme A]


Pssm-ID: 273210 [Multi-domain]  Cd Length: 243  Bit Score: 103.71  E-value: 7.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  14 PHDYHPPESLGFDRRCCLLAAAMDYpGQDSIVIDMGTAITIDLLAG-GHFRGGRILPGIAMSLRGLHEGTALLPEVVLNA 92
Cdd:TIGR00671  90 PNLYKSPKELGIDRVANALAAIKFY-GFNVVVVDAGTALTIDLVDQeGKFLGGAIAPGLGISLHALKDRAAALPKFEIAR 168

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1997949837  93 PAEMLGNDTSNAIQAGVIHLFADALRGAITDFRQYSPQ-ARILITGGDAERWQPGIAGSLYQPHLLLRG 160
Cdd:TIGR00671 169 PDEVLGKSTREAVQSGAVYGVLGLIQGLLKDWKKYFKRkFAVVITGGDGKYLSAFLPFSIYDPHLTVEG 237
PRK13322 PRK13322
pantothenate kinase; Reviewed
 9-166 4.05e-26

pantothenate kinase; Reviewed


Pssm-ID: 237350 [Multi-domain]  Cd Length: 246  Bit Score: 99.25  E-value: 4.05e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837   9 FRRAVPH--------DYHPPESLGFDRRCCLLAAAMDYPGQdSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLH 79
Cdd:PRK13322   77 VVFAKVAaelagvrnGYEDPEQLGIDRWLALLGAFHLAKNA-CLVIDCGTAVTIDLVdADGQHLGGYICPGLYLMRDALR 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  80 EGTALLPEVVLNAPAEMLGNDTSNAIQAGVIHlfadALRGAITDFRQYSPQA-----RILITGGDAERWQPGIAGSLYQP 154
Cdd:PRK13322  156 THTRRIRYDDGTADSLSPGRNTVDAVERGCLL----MLRGFIESQLEQARELwgpdfEIFLTGGDAPLLADHLPQARVVP 231

                         170
                  ....*....|..
gi 1997949837 155 HLLLRGFYLWIR 166
Cdd:PRK13322  232 DLVFVGLAQYCP 243
PRK13328 PRK13328
type III pantothenate kinase;
17-160 1.66e-22

type III pantothenate kinase;


Pssm-ID: 237352 [Multi-domain]  Cd Length: 255  Bit Score: 90.07  E-value: 1.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  17 YHPPESLGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPEVVL----- 90
Cdd:PRK13328   94 YREPAQLGSDRWAGLIGARAAFPGEHLLIATFGTATTLDALrADGRFAGGLILPGLALMMRALARHTAQLPTLDVdaasa 173

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1997949837  91 -NAPAEMLGNDTSNAIQAGVIHLFADALRGAITDF-RQYSPQARILITGGDAERWQPGIAGSL-YQPHLLLRG 160
Cdd:PRK13328  174 aAGAVAPFADDTPDAISAGCLAAQAGLIERAWRDLaARWQAPVRLVLSGGAADAVAPALTVPHtRHDNLVLLG 246
PRK13321 PRK13321
type III pantothenate kinase;
13-166 2.80e-21

type III pantothenate kinase;


Pssm-ID: 237349 [Multi-domain]  Cd Length: 256  Bit Score: 86.85  E-value: 2.80e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  13 VPHDYHPPESLGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLLAG-GHFRGGRILPGIAMSLRGLHEGTALLPEVVLN 91
Cdd:PRK13321   96 LKIRYDNPREVGADRIVNAVAARRLYPDRNLIVVDFGTATTFDCVSGkGEYLGGAICPGILISMEALSQKTAKLPRVEIA 175

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1997949837  92 APAEMLGNDTSNAIQAGVIHLFADALRGAITDFRQYSPQ-ARILITGGDAERWQPGIAG-SLYQPHLLLRGF-YLWIR 166
Cdd:PRK13321  176 KPPSAIGKSTVSSIQSGLYYGYAGLVEGIVARIKAELGGpPRVIATGGFASLIAKESRCfDHVDPDLLLEGLrILYQM 253
PRK13329 PRK13329
pantothenate kinase; Reviewed
 17-145 2.78e-15

pantothenate kinase; Reviewed


Pssm-ID: 183979 [Multi-domain]  Cd Length: 249  Bit Score: 70.79  E-value: 2.78e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  17 YHPPESLGFDRRCCLLAAaMDYPGQDSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLP---EVVLNA 92
Cdd:PRK13329   96 YDHPARLGADRWVALIGA-RHGPARPCLVVMVGTAVTVDALdADGEFLGGLILPGHGLMLRALESGTAGLHvptGEVREF 174

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1997949837  93 PaemlgNDTSNAIQAGVIHlfadALRGAITD-FRQYSPQA----RILITGGDAERWQP 145
Cdd:PRK13329  175 P-----TNTSDALTSGGTQ----AIAGAVERmFRHLAQHCgaepECLLTGGAAWKLAP 223
PRK13324 PRK13324
type III pantothenate kinase;
23-160 5.87e-14

type III pantothenate kinase;


Pssm-ID: 106284 [Multi-domain]  Cd Length: 258  Bit Score: 67.34  E-value: 5.87e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  23 LGFDRRCCLLAAAMDYPGQDSIVIDMGTAITIDLLA-GGHFRGGRILPGIAMSLRGLHEGTALLPEVVLNAPAEMLGNDT 101
Cdd:PRK13324  106 VGADRIASCISAIADHPNKDLLIIDLGTATTFDLVTkDKKYLSGSIMPGVKLSLNALCQGASQLSSVTIVKPEVAIGYDT 185

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837 102 SNAIQAGVIHLFADALRGAIT-DFRQYSPQARILITGGDAERWQPGIAGSLYQPHLLLRG 160
Cdd:PRK13324  186 KTNIRSGLYYGHLGALKELKRrSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPDLILRG 245
PRK13333 PRK13333
type III pantothenate kinase;
21-160 4.77e-12

type III pantothenate kinase;


Pssm-ID: 183981 [Multi-domain]  Cd Length: 206  Bit Score: 61.10  E-value: 4.77e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  21 ESLGFDRR--CCLLAaamdypgqDSIVIDMGTAITIDLLAGGHFRGGRILPGIAMSLRGLHEGTALL-----PEVVLNAp 93
Cdd:PRK13333   70 QGLGIDRIaaCYAIE--------DGVVVDAGSAITVDIMSNGIHLGGFILPGIAAYKKAYKKISPRLkqpfnAQISLDA- 140

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1997949837  94 aemLGNDTSNAIQAGVIhlfadalRGAITDFRQYSPQARILITGGDAERWQPGIAGSLYQPHLLLRG 160
Cdd:PRK13333  141 ---LPQNTRDAISYGVI-------KSIILLIEKLAKNKKIYFTGGDGKFLSKFFPNAIYDERLVFRG 197
PRK13327 PRK13327
type III pantothenate kinase;
17-164 1.63e-10

type III pantothenate kinase;


Pssm-ID: 183977 [Multi-domain]  Cd Length: 242  Bit Score: 57.54  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  17 YHPPESLGFDRRCCLLAAAMDYPgqdSIVIDMGTAITIDLL-AGGHFRGGRILPGIAMSLRGLHEGTALLPeVVLNAPAE 95
Cdd:PRK13327   91 YADPSRFGVDRFLALLGARGDAP---VLVVGVGTALTIDLLgADGLHHGGRIAASPTTMREALHARAVQLP-ASGGDYVE 166

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1997949837  96 mLGNDTSNAIQAG----VIHLFADALRGAitdFRQYSPQARILITGGDAERWQPGIAGSLYQPHLLLRGFYLW 164
Cdd:PRK13327  167 -FANDTDDALTSGcdgaAVALIERSLQHA---HRSLGQPVRLLVHGGGAPPLLPLLPDAEFRPALVLDGLATW 235
PRK13326 PRK13326
type III pantothenate kinase;
23-160 4.49e-09

type III pantothenate kinase;


Pssm-ID: 237351  Cd Length: 262  Bit Score: 53.64  E-value: 4.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  23 LGFDRRCCLLAAAMDYPGQDSIVIDMGTAITI------DLLAGGHFRGGRILpgiamSLRGLHEGTALLPEVVLNAPAEM 96
Cdd:PRK13326  108 LGSDVFANLVGAIEYYNINDALVVDLGTACTIfavsrqDGILGGLINGGPFT-----NLNALLDNAYLLKDFNLSVPKNL 182

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1997949837  97 LGNDTSNAIQAGVIHLFADALRGAITDFRQ-YSPQARILITGGDAERWQPGIAGS-LYQPHLLLRG 160
Cdd:PRK13326  183 LGLSTSDSVNSGVIYQYKYLIEGVYHDLKRnYDREFNLIITGGNSNLILPLISVDfIFNLYLTLEG 248
PRK13325 PRK13325
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/type III pantothenate kinase;
12-142 1.07e-04

bifunctional biotin--[acetyl-CoA-carboxylase] ligase/type III pantothenate kinase;


Pssm-ID: 183976 [Multi-domain]  Cd Length: 592  Bit Score: 41.62  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1997949837  12 AVPHDYHPPESLGFDRRCCLLAAAMdYPGQDSIVIDMGTAITIDLLAG-GHFRGGRILPGIAMSLRGLHEGTAllpevVL 90
Cdd:PRK13325  421 GIRNHYRHPEEHGSDRWFNALGSRR-FSRNACVVVSCGTAVTVDALTDdGHYLGGTIMPGFHLMKESLAVRTA-----NL 494

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1997949837  91 NAPAEM---LGNDTSNAIQAGVIHLFADA---LRGAITDFRQYSPQARILITGGDAER 142
Cdd:PRK13325  495 NRHAGKrypFPTTTGNAVASGMMDAVCGSvmmMHGRLKEKTGAGKPVDVIITGGGAAK 552
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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