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Conserved domains on  [gi|1998155746|ref|WP_206513381|]
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MULTISPECIES: pyrBI operon leader peptide [Enterobacter]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PyrBI_leader super family cl23981
PyrBI operon leader peptide; This family consists of the pyrBI operon leader peptides. The ...
 1-26 4.92e-07

PyrBI operon leader peptide; This family consists of the pyrBI operon leader peptides. The expression of the pyrBI operon, which encodes the subunits of the pyrimidine biosynthetic enzyme aspartate transcarbamylase. is regulated primarily through a UTP-sensitive transcriptional attenuation control mechanism. In this mechanism, the concentration of UTP determines the extent of coupling between transcription and translation within the pyrBI leader region, hence determining the level of rho-independent transcriptional termination at an attenuator preceding the pyrB gene.


The actual alignment was detected with superfamily member PRK10224:

Pssm-ID: 305138  Cd Length: 44  Bit Score: 39.90  E-value: 4.92e-07
                         10        20
                 ....*....|....*....|....*.
gi 1998155746  1 MVKRVRHNVLQRLKSDAGLPFFFPLL 26
Cdd:PRK10224   1 MVQCVRHFVLPRLKKDAGLPFFFPLI 26
 
Name Accession Description Interval E-value
PRK10224 PRK10224
pyr operon leader peptide;
1-26 4.92e-07

pyr operon leader peptide;


Pssm-ID: 236664  Cd Length: 44  Bit Score: 39.90  E-value: 4.92e-07
                         10        20
                 ....*....|....*....|....*.
gi 1998155746  1 MVKRVRHNVLQRLKSDAGLPFFFPLL 26
Cdd:PRK10224   1 MVQCVRHFVLPRLKKDAGLPFFFPLI 26
PyrBI_leader pfam08052
PyrBI operon leader peptide; This family consists of the pyrBI operon leader peptides. The ...
 1-34 4.11e-06

PyrBI operon leader peptide; This family consists of the pyrBI operon leader peptides. The expression of the pyrBI operon, which encodes the subunits of the pyrimidine biosynthetic enzyme aspartate transcarbamylase. is regulated primarily through a UTP-sensitive transcriptional attenuation control mechanism. In this mechanism, the concentration of UTP determines the extent of coupling between transcription and translation within the pyrBI leader region, hence determining the level of rho-independent transcriptional termination at an attenuator preceding the pyrB gene.


Pssm-ID: 285317  Cd Length: 44  Bit Score: 37.63  E-value: 4.11e-06
                         10        20        30
                 ....*....|....*....|....*....|....
gi 1998155746  1 MVKRVRHNVLQRLKSDAGLPFFFPLLNlFPEPLI 34
Cdd:pfam08052  1 MVQCVRHFVLPRLKKDAGLPFFFPLIT-HSQPLI 33
 
Name Accession Description Interval E-value
PRK10224 PRK10224
pyr operon leader peptide;
1-26 4.92e-07

pyr operon leader peptide;


Pssm-ID: 236664  Cd Length: 44  Bit Score: 39.90  E-value: 4.92e-07
                         10        20
                 ....*....|....*....|....*.
gi 1998155746  1 MVKRVRHNVLQRLKSDAGLPFFFPLL 26
Cdd:PRK10224   1 MVQCVRHFVLPRLKKDAGLPFFFPLI 26
PyrBI_leader pfam08052
PyrBI operon leader peptide; This family consists of the pyrBI operon leader peptides. The ...
 1-34 4.11e-06

PyrBI operon leader peptide; This family consists of the pyrBI operon leader peptides. The expression of the pyrBI operon, which encodes the subunits of the pyrimidine biosynthetic enzyme aspartate transcarbamylase. is regulated primarily through a UTP-sensitive transcriptional attenuation control mechanism. In this mechanism, the concentration of UTP determines the extent of coupling between transcription and translation within the pyrBI leader region, hence determining the level of rho-independent transcriptional termination at an attenuator preceding the pyrB gene.


Pssm-ID: 285317  Cd Length: 44  Bit Score: 37.63  E-value: 4.11e-06
                         10        20        30
                 ....*....|....*....|....*....|....
gi 1998155746  1 MVKRVRHNVLQRLKSDAGLPFFFPLLNlFPEPLI 34
Cdd:pfam08052  1 MVQCVRHFVLPRLKKDAGLPFFFPLIT-HSQPLI 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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