|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
24-277 |
4.23e-74 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 227.39 E-value: 4.23e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 24 DRTQQKQGDGKSDSRRSEGPRDGLVRLYGLHTVRAALDNPqRRIKHMRVTRNAAARLE--LGEPSALPFPVEIVEPRAID 101
Cdd:COG0566 3 SPSNPRVKDLRKLRDKKYREEEGLFLAEGRHAVEEALKAG-REIEELLVTEGALDRLAelLALAKAAGIPVYEVSREVLD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 102 GLTGpDAVHQGVLIEAEPLKPRPLGDL----EGAGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAK 177
Cdd:COG0566 82 KLSG-TETHQGVLAVVRPPEYADLEDLlaeaGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 178 AASGALEHIDHLTVRNLAEALEELSAAGFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPG 257
Cdd:COG0566 161 ASAGALFHVPVARVTNLADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAG 240
|
250 260
....*....|....*....|
gi 1998276797 258 AIRSLNVSNAAAVSLYAARQ 277
Cdd:COG0566 241 GVESLNVAVAAAILLYEAAR 260
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
133-275 |
2.43e-56 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 177.96 E-value: 2.43e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLD 212
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 213 SDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA 275
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
49-277 |
4.91e-48 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 159.82 E-value: 4.91e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 49 RLYGLHTVRAALDNPQRrIKHMRVTRNAAARLELGEPSALPFPVEIVEPRAIDGLTgPDAVHQGVLIEAEPLKPRPLGDL 128
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQR-VFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLT-KGGNHQGIAAKVKPILYKDLNDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 129 ------EGAGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELS 202
Cdd:TIGR00186 81 yktaksKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKLK 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1998276797 203 AAGFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA-RQ 277
Cdd:TIGR00186 161 ESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIkRQ 236
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
132-273 |
3.08e-44 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 146.91 E-value: 3.08e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 132 GLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHS-PSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIG 210
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSaDPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 211 LDSDGPAQLEATFAaDRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLY 273
Cdd:pfam00588 81 TSLGGKSLYEIDFP-KKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
50-280 |
2.44e-34 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 124.31 E-value: 2.44e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 50 LYGLHTVRAALDN-PQRRIKHMRVTRNAAARLE--LGEPSALPFPVEIVEPRAIDGLTGpDAVHQGVLIEAEPLKPRPLG 126
Cdd:PRK11181 5 IYGIHAVQALLERaPERFIEVFVLKGREDKRLLplINELEAQGIVIQLANRQTLDEKAE-GAVHQGIIARVKPGRQLQEN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 127 DLEG------AGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEE 200
Cdd:PRK11181 84 DLPDllasleQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLARTMRM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 201 LSAAGFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLY-AARQYL 279
Cdd:PRK11181 164 LQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFeAVRQRS 243
|
.
gi 1998276797 280 G 280
Cdd:PRK11181 244 A 244
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
50-119 |
2.68e-11 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 57.93 E-value: 2.68e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1998276797 50 LYGLHTVRAALDNPqRRIKHMRVTRNAAARLE--LGEPSALPFPVEIVEPRAIDGLTGpDAVHQGVLIEAEP 119
Cdd:smart00967 1 IEGRHAVEEALKSG-RRIKELYLTEGRAERLKelLKLAKERGIKVIEVSKKELDKLSG-TANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
24-277 |
4.23e-74 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 227.39 E-value: 4.23e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 24 DRTQQKQGDGKSDSRRSEGPRDGLVRLYGLHTVRAALDNPqRRIKHMRVTRNAAARLE--LGEPSALPFPVEIVEPRAID 101
Cdd:COG0566 3 SPSNPRVKDLRKLRDKKYREEEGLFLAEGRHAVEEALKAG-REIEELLVTEGALDRLAelLALAKAAGIPVYEVSREVLD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 102 GLTGpDAVHQGVLIEAEPLKPRPLGDL----EGAGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAK 177
Cdd:COG0566 82 KLSG-TETHQGVLAVVRPPEYADLEDLlaeaGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 178 AASGALEHIDHLTVRNLAEALEELSAAGFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPG 257
Cdd:COG0566 161 ASAGALFHVPVARVTNLADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAG 240
|
250 260
....*....|....*....|
gi 1998276797 258 AIRSLNVSNAAAVSLYAARQ 277
Cdd:COG0566 241 GVESLNVAVAAAILLYEAAR 260
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
133-275 |
2.43e-56 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 177.96 E-value: 2.43e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLD 212
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 213 SDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA 275
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
49-277 |
4.91e-48 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 159.82 E-value: 4.91e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 49 RLYGLHTVRAALDNPQRrIKHMRVTRNAAARLELGEPSALPFPVEIVEPRAIDGLTgPDAVHQGVLIEAEPLKPRPLGDL 128
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQR-VFILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLT-KGGNHQGIAAKVKPILYKDLNDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 129 ------EGAGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELS 202
Cdd:TIGR00186 81 yktaksKKQPFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTITKLK 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1998276797 203 AAGFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA-RQ 277
Cdd:TIGR00186 161 ESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIkRQ 236
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
132-273 |
3.08e-44 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 146.91 E-value: 3.08e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 132 GLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHS-PSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIG 210
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSaDPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 211 LDSDGPAQLEATFAaDRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLY 273
Cdd:pfam00588 81 TSLGGKSLYEIDFP-KKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
133-275 |
3.33e-39 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 134.09 E-value: 3.33e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLD 212
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 213 SDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA 275
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
133-274 |
3.06e-35 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 124.17 E-value: 3.06e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLD 212
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGTS 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1998276797 213 SDGPA-QLEATFAADRIA---------LVLGAEGKGLRQKTRDTVTALARLDMPGA-----IRSLNVSNAAAVSLYA 274
Cdd:cd18105 81 APPSAsSDKKTIPANELSelllekptiLVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGILLHS 157
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
50-280 |
2.44e-34 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 124.31 E-value: 2.44e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 50 LYGLHTVRAALDN-PQRRIKHMRVTRNAAARLE--LGEPSALPFPVEIVEPRAIDGLTGpDAVHQGVLIEAEPLKPRPLG 126
Cdd:PRK11181 5 IYGIHAVQALLERaPERFIEVFVLKGREDKRLLplINELEAQGIVIQLANRQTLDEKAE-GAVHQGIIARVKPGRQLQEN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 127 DLEG------AGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEE 200
Cdd:PRK11181 84 DLPDllasleQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTNLARTMRM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 201 LSAAGFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLY-AARQYL 279
Cdd:PRK11181 164 LQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFeAVRQRS 243
|
.
gi 1998276797 280 G 280
Cdd:PRK11181 244 A 244
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
133-275 |
4.90e-26 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 99.95 E-value: 4.90e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLD 212
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIYLCGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIALE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998276797 213 SDGPAQ-LEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA 275
Cdd:cd18097 81 TTENSVpLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
134-275 |
5.90e-24 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 94.21 E-value: 5.90e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 134 VLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGL-- 211
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLel 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1998276797 212 DSDGPAQLEATFAAD-RIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA 275
Cdd:cd18082 81 TDGSIPLSEFKFKKPkKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
132-277 |
1.17e-22 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 91.37 E-value: 1.17e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 132 GLVLVLDQVTDPHNVGAIMRSAVAFGVNALVttARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGL 211
Cdd:cd18092 16 DLTVVLENVHDPHNASAVLRTCDAFGVQDVH--VIEPKNKFKKNRGVAMGADKWLDVHRHDSTEECLAALKEQGYRIVAT 93
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1998276797 212 D-SDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAARQ 277
Cdd:cd18092 94 SlSPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQR 160
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
134-272 |
2.84e-20 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 89.07 E-value: 2.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 134 VLVLDQVTDPHNVGAIMRSAVAFGVNALVTTaRHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLDS 213
Cdd:PRK10864 200 VLALEDVGNPHNLGGIMRSCAHFGVKGVVVQ-DAALLESGAAIRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSS 278
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1998276797 214 DGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSL 272
Cdd:PRK10864 279 HKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLL 337
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
133-277 |
7.11e-17 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 75.31 E-value: 7.11e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALV----TTARHSPSesgvLAKAASGALehidhLTVR----NLAEALEELSAA 204
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVIlcdpKTDLFNPN----VIRASLGAV-----FTLPvaeaSSEETLAWLKEN 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1998276797 205 GFQTIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLY-AARQ 277
Cdd:cd18104 72 KIRILATTPKAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYeALRQ 145
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
133-273 |
1.62e-15 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 71.80 E-value: 1.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALV---TTArhSPSESGVLaKAASGALEHIdHLTVRNLAEALEELSAAgFQTI 209
Cdd:cd18109 1 LTLALDGIQDPGNLGTIIRTADWFGIRQIIcspDTV--DPYNPKVV-QASMGSIFRV-QIHYTDLPALLAELKKA-FPVY 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1998276797 210 GLDSDGPAQLEATFAADRIaLVLGAEGKGLRQKTRDTVTalARLDMPGAIR---SLNVSNAAAVSLY 273
Cdd:cd18109 76 GADLDGENLYEFTLPEKGI-LVMGNEGHGISPEVLKLLT--HRLTIPRYGKgaeSLNVAVATAILLS 139
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
133-274 |
1.14e-14 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 69.17 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNA--LVTTARHSPSEsgvlakaASGALehiDHLTVR---NLAEALEELSAAGFQ 207
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEvhLVGRRKFNPFG-------AMGTD---RHVKFRhfdTLAEAKEYLKERGIR 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1998276797 208 TIGLD-SDGPAQLEATFAADRIALVLGAEGKGLRQKTrdtvtaLARLDMPGAI-------RSLNVSNAAAVSLYA 274
Cdd:cd18096 71 LVGVEiVPGAEPIETHPFPGDTAFVLGNEGTGLSDEQ------LAICDGFVYIpqygsgtASLNVSVAASIVLHH 139
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
133-275 |
1.32e-14 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 69.34 E-value: 1.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAA-----GFQ 207
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPSNRELEDWVEARkargtPLQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1998276797 208 TIGLDSDGPAQLEATFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYAA 275
Cdd:cd18107 81 LVGTDEHGDHQIADHDFTRPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYEA 148
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
133-273 |
5.01e-12 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 62.16 E-value: 5.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALE-HIDHLTVRNLAEALEELSAAGFQTIGL 211
Cdd:cd18091 1 LIVVASLIDKPPNLGGLCRTCEIFGVSKLVLPNLAVVEDKQFKALSVSAEKWlPIEEVKPEDLLPYLKEKKQEGYTIVGL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1998276797 212 DSDGPAQLEATFAADR-IALVLGAEGKGLrqktrdTVTALARLD------MPGAIRSLNVSNAAAVSLY 273
Cdd:cd18091 81 EQTANSVSLHDFQFPKkTVLVLGNEKEGI------PAELLSLLDvcveipQLGVIRSLNVHVSGAIAIY 143
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
133-277 |
2.39e-11 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 61.93 E-value: 2.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALvtTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTigld 212
Cdd:PRK11081 20 LTVCMEQVHKPHNVSAIIRTADAVGVHEV--HAVWPGSRMRTMGSTAAGSNSWVQVKTHRTIGDAVAHLKGQGMQI---- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 213 sdgpaqLEATFAADRI-----------ALVLGAEGKGLRQKtrdtvtALARLD------MPGAIRSLNVSNAAAVSLY-A 274
Cdd:PRK11081 94 ------LATHLSDTAVdfreidytrptCILMGQEKTGISQE------ALALADqdiiipMIGMVQSLNVSVASALILYeA 161
|
...
gi 1998276797 275 ARQ 277
Cdd:PRK11081 162 QRQ 164
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
50-119 |
2.68e-11 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 57.93 E-value: 2.68e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1998276797 50 LYGLHTVRAALDNPqRRIKHMRVTRNAAARLE--LGEPSALPFPVEIVEPRAIDGLTGpDAVHQGVLIEAEP 119
Cdd:smart00967 1 IEGRHAVEEALKSG-RRIKELYLTEGRAERLKelLKLAKERGIKVIEVSKKELDKLSG-TANHQGVVAVVKP 70
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
135-277 |
5.04e-11 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 59.39 E-value: 5.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 135 LVLDQVTDPHNVGAIMRSAVAFGVNA-LVTTARHSPSESGVlaKAAsgALEHIDHLTVR---NLAEALEELSAAGFqtIG 210
Cdd:cd18094 2 IVLYEPEIPQNTGNIARTCAATGARLhLIEPLGFSLDDKRL--KRA--GLDYWDHVDLTvhdSWEAFLEALPPGRL--FL 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 211 LDSDGPAQL-EATFAADrIALVLGAEGKGLRQKTRDTVT-ALARLDMPGAIRSLNVSNAAAVSLYAA-RQ 277
Cdd:cd18094 76 FTTKGTKPYtDFDFKPG-DYLVFGRESTGLPEEILDAFPdRRLRIPMRPKVRSLNLSNSVAIVLYEAlRQ 144
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
134-273 |
2.41e-10 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 57.89 E-value: 2.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 134 VLVldQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTV-RNLAEALEELSAA-------- 204
Cdd:cd18093 4 VLV--EPQHPGNIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAEDVLENAKVyDTLEEALADCDLVvattarpr 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 205 GFQTIGLD-SDGPAQLEATFAADRIALVLGAEGKGLrqkTRDTV---TALARLDMPGAIRSLNVSNAAAVSLY 273
Cdd:cd18093 82 GLRRPLLTpRELAELLKEHAAGGKVALVFGREDSGL---TNEELalcDLLVTIPTNPEYPSLNLAQAVAIVLY 151
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
133-273 |
4.84e-09 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 53.79 E-value: 4.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 133 LVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARH-SPSESGVLaKAASGAleHIDHLTVRNL-AEALEELSAAGFQTIG 210
Cdd:cd18106 1 LTVICDNIRDPGNLGSILRSAAAAGCSKVLLTKGCvDPWEPKVL-RAGAGA--HFRLPIYGNLsWDDIPNYLPDDSKVFL 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1998276797 211 LDSDGPAQL--EATFAADRIALVLGAEGKGLRQKTRDtvtaLARLD--------MPGAIRSLNVSNAAAVSLY 273
Cdd:cd18106 78 ADNNLPVQPydSIDYCSGPIVLVIGGETHGVSPEAYK----LAHSTggsrvhipLANGVDSLNSAVAASILLF 146
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
143-277 |
7.46e-09 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 53.50 E-value: 7.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 143 PHNVGAIMRSAVAFGVNA-LV------TTARHspsesgvLAKAAsgaLEHIDHLTVR---NLAEALEELSAAGFqtIGLD 212
Cdd:COG0219 12 PQNTGNIIRLCAATGARLhLIeplgfsLDDKK-------LKRAG---LDYWELVDLTvhdSWEAFLEALPGGRL--FLFT 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1998276797 213 SDGPAQL-EATFAADRIaLVLGAEGKGLRQKTRDT-VTALARLDMPGAIRSLNVSNAAAVSLYAA-RQ 277
Cdd:COG0219 80 TKGTKPYtDVDYQPGDV-LLFGRETAGLPEEVLAApADQRLRIPMRPGVRSLNLSNAVAIVLYEAlRQ 146
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
134-274 |
7.80e-08 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 50.55 E-value: 7.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 134 VLVLDQVTDPHNVGAIMRSAVAFGVNALVTTARHSPSESGVLAKAASGALEHIDHLTVRNLAEALEELSAAGFQTIGLDS 213
Cdd:cd18108 2 VVVLDGVRIVGNIGAIVRTSLALGAAGIVLVDSDLATVADRRLLRASRGYVFSLPVVLADREEAVAFLRDNDIPLMTLDA 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1998276797 214 DGPAQLEA-TFAADRIALVLGAEGKGLRQKTRDTVTALARLDMPGAIRSLNVSNAAAVSLYA 274
Cdd:cd18108 82 DGDVPVKElGDRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
137-273 |
6.40e-07 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 47.64 E-value: 6.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 137 LDQVTDPHNVGAIMRSAVAFGVNALVTT----ARHSPSeSGVLAKAASGALEHIDhlTVRNLAEALEElsaaGFQTIGLD 212
Cdd:cd18098 5 IENPKTPKNVGTLWRAAGCLGASFVFTIgaryKRRKQS-TDTSKAWRHIPLFHYD--DLEDLAEPLPF----GAVLVAVE 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1998276797 213 SDGPAQLEATFA-ADRIALVLGAEGKGLRQKTRDTVTALARLdmPGAIrSLNVSNAAAVSLY 273
Cdd:cd18098 78 LTEGATPLPDFKhPDRAVYLLGPEDGGLPQEVLARCHHVVYL--PTRG-SLNVAVAGSIVLY 136
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
50-121 |
6.47e-07 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 46.08 E-value: 6.47e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1998276797 50 LYGLHTVRAALDNPqRRIKHMRVTRNAAA---RLELGEPSALPFPVEIVEPRAIDGLTGpDAVHQGVLIEAEPLK 121
Cdd:pfam08032 2 IYGRHAVLEALKSG-PEIKKLYLTEGRRDprlKELLKLAKERGIKVEEVDRKKLDKLSG-TANHQGVVAEVKPYE 74
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
131-273 |
2.50e-04 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 41.64 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 131 AGLVLVLDQVTDPHNVGAIMRSAVAFGVNALVTTA-RHSPSESGVlaKAASGALEHIDHLTV-RNLAEALEELS-----A 203
Cdd:COG0565 2 DNIRVVLVEPQHPGNIGAAARAMKNFGLSDLRLVNpRGWPDEEAR--AMASGADDVLENARVvDTLEEALADCDlvvgtT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1998276797 204 AGFQTIGLDSDGPAQ----LEATFAADRIALVLGAEGKGLrqkTRDtvtALARLDMPGAI------RSLNVSNAAAVSLY 273
Cdd:COG0565 80 ARPRELRKPVLTPREaaeeLLARAAGGKVALVFGRERSGL---TNE---ELALCDALVTIptnpeyPSLNLAQAVQVVAY 153
|
|
| |
