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Conserved domains on  [gi|2005287079|ref|WP_206907660|]
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nucleoside triphosphate pyrophosphatase [Enterococcus sp. DIV0660C]

Protein Classification

Maf family protein( domain architecture ID 10785471)

multicopy associated filamentation (Maf) family protein is involved in septum formation and also has a role as a house-cleaning NTP pyrophosphatase

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0009117|GO:0047429|GO:0009146|GO:0000166
PubMed:  24210219
SCOP:  4000520

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 1-184 3.72e-85

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440193  Cd Length: 189  Bit Score: 248.80  E-value: 3.72e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQtEQTLVIASDTTVIHHQKILG 80
Cdd:COG0424     1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-PDALVLGADTVVVLDGRILG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  81 KPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERI-LAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:COG0424    80 KPADAEEARAMLRRLSGRTHRVHTGVALIDPGGRLWTrVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALV 159

                         170       180
                  ....*....|....*....|....*
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:COG0424   160 ERIEGSYSNVVGLPLIELLELLREL 184
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 1-184 3.72e-85

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 248.80  E-value: 3.72e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQtEQTLVIASDTTVIHHQKILG 80
Cdd:COG0424     1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-PDALVLGADTVVVLDGRILG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  81 KPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERI-LAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:COG0424    80 KPADAEEARAMLRRLSGRTHRVHTGVALIDPGGRLWTrVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALV 159

                         170       180
                  ....*....|....*....|....*
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:COG0424   160 ERIEGSYSNVVGLPLIELLELLREL 184
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 3-181 6.10e-79

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 232.75  E-value: 6.10e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQTLVIASDTTVIHHQKILGKP 82
Cdd:cd00555     1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPDALVIGADTVVVLDGRILGKP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  83 VDLADAKATLRSLSGETHQVYTAVVL-KSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVKE 161
Cdd:cd00555    81 KDREEAREMLKRLSGRTHEVYTGVALiDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGALIER 160

                         170       180
                  ....*....|....*....|
gi 2005287079 162 ISGDYYSIVGFPIGAVNQAL 181
Cdd:cd00555   161 IEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 3-184 1.08e-76

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 226.90  E-value: 1.08e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPID-GEDPIAYVQRMAYEKAQAVVeqqteqtlvIASDTTVIHhqkILGK 81
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKeDPAPEEYVLRLARAKAEALV---------IGADTVVVL---ILGK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  82 PVDLADAKATLRSLSGETHQVYTAVVL---KSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAF 158
Cdd:pfam02545  69 PKDEEEARAMLKRLSGRTHEVYTGVALinpGGGTGGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGAAL 148

                         170       180
                  ....*....|....*....|....*.
gi 2005287079 159 VKEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:pfam02545 149 VERIEGDYSNVVGLPLIELLRLLREL 174
PRK00648 PRK00648
Maf-like protein; Reviewed
 1-184 2.43e-64

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 196.28  E-value: 2.43e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPA-DIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQTLVIASDTTVIHHQKIL 79
Cdd:PRK00648    3 YKIILASSSPRRKEILEGFRIPFEVVPSpFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDELIITADTIVWYDGKVL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  80 GKPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:PRK00648   83 GKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGIQEWGGLIV 162

                         170       180
                  ....*....|....*....|....*
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:PRK00648  163 KKIEGSYYNVMGLPIQTLYEELKEL 187
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 1-182 5.50e-54

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 169.89  E-value: 5.50e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQtLVIASDTTVIHHQKILG 80
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELLADA-LIIGADTVVILDGEIYG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  81 KPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVK 160
Cdd:TIGR00172  82 KPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGAPLIK 161

                         170       180
                  ....*....|....*....|..
gi 2005287079 161 EISGDYYSIVGFPIGAVNQALK 182
Cdd:TIGR00172 162 KIDGDYSNVVGLPLEKLLGALR 183
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 1-184 3.72e-85

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 248.80  E-value: 3.72e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQtEQTLVIASDTTVIHHQKILG 80
Cdd:COG0424     1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-PDALVLGADTVVVLDGRILG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  81 KPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERI-LAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:COG0424    80 KPADAEEARAMLRRLSGRTHRVHTGVALIDPGGRLWTrVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGAALV 159

                         170       180
                  ....*....|....*....|....*
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:COG0424   160 ERIEGSYSNVVGLPLIELLELLREL 184
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 3-181 6.10e-79

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 232.75  E-value: 6.10e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQTLVIASDTTVIHHQKILGKP 82
Cdd:cd00555     1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPDALVIGADTVVVLDGRILGKP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  83 VDLADAKATLRSLSGETHQVYTAVVL-KSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVKE 161
Cdd:cd00555    81 KDREEAREMLKRLSGRTHEVYTGVALiDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGALIER 160

                         170       180
                  ....*....|....*....|
gi 2005287079 162 ISGDYYSIVGFPIGAVNQAL 181
Cdd:cd00555   161 IEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 3-184 1.08e-76

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 226.90  E-value: 1.08e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPID-GEDPIAYVQRMAYEKAQAVVeqqteqtlvIASDTTVIHhqkILGK 81
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKeDPAPEEYVLRLARAKAEALV---------IGADTVVVL---ILGK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  82 PVDLADAKATLRSLSGETHQVYTAVVL---KSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAF 158
Cdd:pfam02545  69 PKDEEEARAMLKRLSGRTHEVYTGVALinpGGGTGGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGAAL 148

                         170       180
                  ....*....|....*....|....*.
gi 2005287079 159 VKEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:pfam02545 149 VERIEGDYSNVVGLPLIELLRLLREL 174
PRK00648 PRK00648
Maf-like protein; Reviewed
 1-184 2.43e-64

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 196.28  E-value: 2.43e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPA-DIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQTLVIASDTTVIHHQKIL 79
Cdd:PRK00648    3 YKIILASSSPRRKEILEGFRIPFEVVPSpFVEESYPYSLDPEEITLELARLKAEAVRSDLFPDELIITADTIVWYDGKVL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  80 GKPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:PRK00648   83 GKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGIQEWGGLIV 162

                         170       180
                  ....*....|....*....|....*
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALKEF 184
Cdd:PRK00648  163 KKIEGSYYNVMGLPIQTLYEELKEL 187
PRK00078 PRK00078
Maf-like protein; Reviewed
 1-183 3.63e-57

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 178.00  E-value: 3.63e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPI-AYVQRMAYEKAQAVVEQ-QTEQTLVIASDTTVIHHQKI 78
Cdd:PRK00078    1 MKIILASASERRQELLKRILEDFQVIVSDFDESSVPFKGNIeSYVMNLAEGKARSVSKKlDQESSIVIGCDTIVAFNGKV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  79 LGKPVDLADAKATLRSLSGETHQVYTAVVL--KSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAG 156
Cdd:PRK00078   81 LGKPKDEEDAFEMLKALSGNEHEVYSGIAIldTKSNKIIKDFVCTEVKFSKLTDRQIRKYINTGEPMDKAGAYGIQGKGG 160

                         170       180
                  ....*....|....*....|....*..
gi 2005287079 157 AFVKEISGDYYSIVGFPIGAVNQALKE 183
Cdd:PRK00078  161 VFVEEINGCYYNVVGLPLNKLYKMLEE 187
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 1-182 5.50e-54

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 169.89  E-value: 5.50e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQtLVIASDTTVIHHQKILG 80
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELLADA-LIIGADTVVILDGEIYG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  81 KPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVK 160
Cdd:TIGR00172  82 KPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGAPLIK 161

                         170       180
                  ....*....|....*....|..
gi 2005287079 161 EISGDYYSIVGFPIGAVNQALK 182
Cdd:TIGR00172 162 KIDGDYSNVVGLPLEKLLGALR 183
PRK14368 PRK14368
Maf-like protein; Provisional
 3-182 4.73e-49

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 157.63  E-value: 4.73e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEqQTEQTLVIASDTTVIHHQKILGKP 82
Cdd:PRK14368    7 IVLASASPRRSELLASAGIEFDVVPADIPEEPLPGEEPVDHVLRLAREKARAAAA-LAEGRFFIGADTIVVCDGEIMGKP 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  83 VDLADAKATLRSLSGETHQVYTAVVLKSKEREErILAQAEVT---FYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:PRK14368   86 KDEADAVRMLKKLSGVPHEVITGFAVYDRERDG-CVTKAVRTkvfFKPLRDEEIRDYIATGCPMDKAGAYAIQGGAAHMV 164

                         170       180
                  ....*....|....*....|...
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALK 182
Cdd:PRK14368  165 RKIDGSYTNVVGLPLCEVVEALR 187
PRK14363 PRK14363
Maf-like protein; Provisional
 1-183 6.85e-47

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 152.36  E-value: 6.85e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPIdgEDPIAYVQRMAYEKAQAVVEQQ-TEQTLVIASDTTVIHHQKIL 79
Cdd:PRK14363    1 MRIILASSSPRRRQLMELLGIEFEVEKPDVEEEFL--ESPEETVRELSLRKAEWVFKKRkEEEILVIGSDTVVVLDGNIL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  80 GKPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFV 159
Cdd:PRK14363   79 GKPESLEEAKGMLKKLSGRWHVVYTGVAFVSSETKDVIVSSTKVRFRELPESVIDYYVEKYRPLDKAGAYGIQDFAAVFV 158

                         170       180
                  ....*....|....*....|....
gi 2005287079 160 KEISGDYYSIVGFPIGAVNQALKE 183
Cdd:PRK14363  159 EKIEGDFFTVVGFPLGMVWQYLYE 182
PRK01441 PRK01441
Maf-like protein; Reviewed
 2-174 1.62e-45

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 149.10  E-value: 1.62e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   2 KIILASQSPRRKELLSRLVSE-FAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQ-QTEQTL----VIASDTTVIHH 75
Cdd:PRK01441    6 KLVLASGSPRRVELLNQAGIEpDRLMPADIDETPKRAEHPRSLARRLSREKAEAALEAlQGDDDWrgayILAADTVVAVG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  76 QKILGKPVDLADAKATLRSLSGETHQVYTAVVLKSKEREER-ILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSF 154
Cdd:PRK01441   86 RRILPKAELVDEASQCLRLLSGRNHRVYTGVCLVTPDGKLRqKLVETRVRFKRLSREDIEAYLASGEWRGKAGGYAIQGI 165

                         170       180
                  ....*....|....*....|
gi 2005287079 155 AGAFVKEISGDYYSIVGFPI 174
Cdd:PRK01441  166 AGSFVVKLVGSYTNVVGLPL 185
PRK04694 PRK04694
Maf-like protein; Reviewed
 5-184 2.58e-44

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 145.49  E-value: 2.58e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   5 LASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQ---AVVEQQTEQTLVIASDTTVIHHQKILGK 81
Cdd:PRK04694    4 LASRSPRRRELLQRLDVPFQTLQLDVPEVRAADESPDHYVQRVALEKAHaglALVQAADADAIVLGSDTEVVLGERVFGK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  82 PVDLADAKATLRSLSGETHQVYTAVVLKSKER-EERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVK 160
Cdd:PRK04694   84 PVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRaPAQALVVSEVTFDLLDDAQIAAYAASGEPMGKAGAYAIQGRAERFIR 163

                         170       180
                  ....*....|....*....|....
gi 2005287079 161 EISGDYYSIVGFPIGAVNQALKEF 184
Cdd:PRK04694  164 HLSGSYSGVMGLPLYQTSQLLTAF 187
PRK14361 PRK14361
Maf-like protein; Provisional
 3-182 1.09e-42

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 141.22  E-value: 1.09e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPIDgEDPIAYVQRMAYEKAQAVVEQQTEqTLVIASDTTVIHHQKILGKP 82
Cdd:PRK14361    1 VILASGSPRRRELLENLGVPFQVVVSGEAEDSTE-TDPARLAAELALLKARAVARLHPD-AVVIAADTVVALGGVLLAKP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  83 VDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVKEI 162
Cdd:PRK14361   79 ADEAENEAFLRVLSGRTHQVYTGVAVLSRGTEQVGVERTDVTFRALTAAEISFYARSGEGLDKAGGYGIQGVGMALVSRV 158

                         170       180
                  ....*....|....*....|
gi 2005287079 163 SGDYYSIVGFPIGAVNQALK 182
Cdd:PRK14361  159 EGDYSNVVGFPLSLVIRLLR 178
PRK14364 PRK14364
Maf-like protein; Provisional
 5-182 1.20e-39

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 133.20  E-value: 1.20e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   5 LASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVeQQTEQTLVIASDTTVIHHQKILGKPVD 84
Cdd:PRK14364    1 LASSSPRRRELLQQLGLNFEIYSPDIDESVHEGELVHQYVERLAREKAQAVL-NIFPDSVIIAADTSLGLDGQIIGKPDS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  85 LADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVKEISG 164
Cdd:PRK14364   80 KQHAFDIWKQLSGRWHDVFSGICIATQQQILSQVVQTQVEFASLTTQDMEDYWATGEPVGKAGAYAIQGIASQYIPKIQG 159

                         170
                  ....*....|....*...
gi 2005287079 165 DYYSIVGFPIGAVNQALK 182
Cdd:PRK14364  160 SYSNVVGLPLYEFSQLFK 177
PRK14367 PRK14367
Maf-like protein; Provisional
 5-174 3.46e-39

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 132.50  E-value: 3.46e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   5 LASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQ--QTEQTL----VIASDTTVIHHQKI 78
Cdd:PRK14367    6 LGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTALTLfcETNGTMpdfpLITADTCVVSDGII 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  79 LGKPVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAF 158
Cdd:PRK14367   86 LGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIGGIF 165

                         170
                  ....*....|....*.
gi 2005287079 159 VKEISGDYYSIVGFPI 174
Cdd:PRK14367  166 IQSIEGSFSGIMGLPV 181
PRK14362 PRK14362
Maf-like protein; Provisional
 3-174 1.10e-37

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 128.83  E-value: 1.10e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFA-IQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQtLVIASDTTVIHHQKILGK 81
Cdd:PRK14362   14 VVLASGSPRRREFLEQMGLPFEvILPGAAEPSPIEGEQPEAYARRAAEAKARAVAADHAGR-LVIAADTVVALDGMILGK 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  82 PVDLADAKATLRSLSGETHQVYTAV-VLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVK 160
Cdd:PRK14362   93 PADRADALSMLRRLAGRTHEVVSACcVVLPDGGREVFHAITRVTMWDWPEAALAAYVATGEPSDKAGAYGIQGIGAFLVR 172

                         170
                  ....*....|....
gi 2005287079 161 EISGDYYSIVGFPI 174
Cdd:PRK14362  173 SIEGSWSNVVGLPV 186
PRK14366 PRK14366
Maf-like protein; Provisional
 3-174 7.83e-37

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 126.45  E-value: 7.83e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRL-VSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQtLVIASDTTVIHHQKILGK 81
Cdd:PRK14366    7 LILASSSKQRLALLEQIgVVPGEIVSPDIDESPLKKELPKDYSIRMAKEKAEKVQSLRPDK-FVLGADTVVCCGRRILLK 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  82 PVDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAE-VTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVK 160
Cdd:PRK14366   86 AETEEQAEEYLELLSGRRHRVYTSVCLYTPGGKLHIRSVVTvVKFKRLSKQEIKYYIASGEWKGKAGGCNIQGLAGKFVL 165

                         170
                  ....*....|....
gi 2005287079 161 EISGDYYSIVGFPI 174
Cdd:PRK14366  166 SINGSYSSIIGLPL 179
PRK14365 PRK14365
Maf-like protein; Provisional
 2-183 1.20e-36

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 126.09  E-value: 1.20e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   2 KIILASQSPRRKELLSRLVSE-FAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVeQQTEQTLVIASDTTVIHHQKILG 80
Cdd:PRK14365    3 RIILASASPRRKELLKQLIGDnFLVYPSSYEEPPQPGLDPEELLLKHSLEKARDVA-KHFDSGIIISADTSVFCNGEVLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  81 KPVDLADAKATLRSLSGETHQVYTAVVL----KSKEREERILAQAEVTfyPLTEKEIDTYLATGDYQDKAGSYGIQSFAG 156
Cdd:PRK14365   82 KPASPENAEEMLEKLSGRKFLVITGLTVldldSGKEISEIESTDVWMT--ELSREQILAYVRTGEPLDKAGAFAIQGKGA 159

                         170       180
                  ....*....|....*....|....*..
gi 2005287079 157 AFVKEISGDYYSIVGFPIGAVNQALKE 183
Cdd:PRK14365  160 VLVEKIEGDFFNVVGLPLFRLGKILEK 186
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 3-125 1.34e-32

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 113.36  E-value: 1.34e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVS-EFAIQPADIDETPIDGEdPIAYVQRMAYEKAQAVVEQqTEQTLVIASDTTVIHHQKILGK 81
Cdd:cd00985     1 LILASGSPRRLEELKQIGGiEFEVLPSDIDETGLKGE-PEDTVEELALLKARAVAER-LPDAPVIADDTGLVVDGRPGGK 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2005287079  82 PVDLADAKATLRSLSGETHQVYTAVVLKSKEREERI-LAQAEVTF 125
Cdd:cd00985    79 PARFAEALEMLRGLSGRTAEFVTAVALVDPDGKIITfEGETEGKI 123
PRK02141 PRK02141
Maf-like protein; Reviewed
 2-184 1.73e-28

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 105.22  E-value: 1.73e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   2 KIILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQ--TLVIASDTTVIHHQKIL 79
Cdd:PRK02141   10 RLILASSSRYRRELLERLRLPFDVVSPDIDETPLAGETPAATALRLAAAKARAVAATIDAPpgALVIGSDQVATFDGLQI 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  80 GKPVDLADAKATLRSLSGETHQVYTAVVL--KSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGA 157
Cdd:PRK02141   90 GKPGTHERALAQLQAMRGRTVEFHSALCLydSRTGETQSEDVVTRVRFRTLTDAELDAYLRAETPYDVAGSAKSEGLGIA 169

                         170       180
                  ....*....|....*....|....*...
gi 2005287079 158 FVKEI-SGDYYSIVGFPIGAVNQALKEF 184
Cdd:PRK02141  170 LLDAIdSDDPTALVGLPLIALTRMLRAA 197
PRK02478 PRK02478
Maf-like protein; Reviewed
 1-183 9.27e-27

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 100.58  E-value: 9.27e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   1 MKIILASQSPRRKELLSRLVSEFAIQPADIDETPI------DGEDPIAYVQRMAYEKAQAVVEQQTEqTLVIASDTTVIH 74
Cdd:PRK02478    3 VKLILASKSPFRRALLENAGLEFSAAAADIDERAVeapleeSGATPEDVALVLAEAKAIDVSERFPG-ALVIGCDQTMSL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  75 HQKILGKPVDLADAKATLRSLSGETHQVYTAVVL-KSKEREERILAQAEVTFYPLTEKEIDTYLATgdYQDKA----GSY 149
Cdd:PRK02478   82 GDEVFHKPKDMEEARRHLQKLSGKTHQLNSAVVLvRDGKVLWRHVSIAHMTMRDLDAGFIGRHLAR--VGEKAlssvGAY 159

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2005287079 150 -----GIQSFagafvKEISGDYYSIVGFPIGAVNQALKE 183
Cdd:PRK02478  160 qlegeGIQLF-----EKIEGDYFTILGLPLLPLLAKLRE 193
PRK04056 PRK04056
septum formation inhibitor Maf;
3-185 5.53e-25

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 95.41  E-value: 5.53e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079   3 IILASQSPRRKELLSRLVSEFAIQPADIDETPIDGEDPIAYVQRMAYEKAQAVVEQQTEQTLVIASDTTVIHHQKILGKP 82
Cdd:PRK04056    2 IILASSSSTRANLLKEAGIEFEQKSLDFDEESIKKTSPKEFVYLAVKGKLEQFLKKYGNECNLLVADSVVSCGNKILRKA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2005287079  83 VDLADAKATLRSLSGETHQVYTAVVLKSKEREERILAQAEVTFYPLTEKEIDTYLATGDYQDKAGSYGIQSFAGAFVKEI 162
Cdd:PRK04056   82 KDKEEAREMLKLQSGNEISVLTCMILKSPEKEWLDLSVTTYRFKKFDEDDLEKYLESGLWQGKAGACMVEGFHKKYIKSV 161

                         170       180
                  ....*....|....*....|...
gi 2005287079 163 SGDYYSIVGFPIgavnQALKEFL 185
Cdd:PRK04056  162 SGNESTAMGLNV----EKLKGFL 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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